## Tue Dec 16 16:37:35 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WH3_bin.59.fa -m mmseqs --itype genome -o WH3_bin.59 --output_dir /data/result/bins/wyx/egg/WH3_bin.59 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WH3_k127_1001827_1	1479239.JQMU01000001_gene2266	0.0	1017.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2K0C4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
WH3_k127_1001827_0	1479239.JQMU01000001_gene2265	0.0	1093.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2TRWD@28211|Alphaproteobacteria,2JZVN@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0729 Outer membrane protein	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
WH3_k127_1001827_4	1248917.ANFX01000012_gene1855	9.444e-168	529.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2TQY8@28211|Alphaproteobacteria,2K00M@204457|Sphingomonadales	204457|Sphingomonadales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
WH3_k127_1001827_3	1248917.ANFX01000012_gene1854	2.625e-250	777.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K130@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
WH3_k127_1001827_5	1479239.JQMU01000001_gene2262	4.782e-157	500.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2K0B1@204457|Sphingomonadales	204457|Sphingomonadales	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WH3_k127_1001827_2	1479239.JQMU01000001_gene2261	4.295e-315	974.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2K1UV@204457|Sphingomonadales	204457|Sphingomonadales	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WH3_k127_1001827_6	1248917.ANFX01000012_gene1852	2.626e-141	455.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,2K1PD@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WH3_k127_1001827_7	1248917.ANFX01000012_gene1851	2.388e-48	177.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2UF4Z@28211|Alphaproteobacteria,2K60Q@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WH3_k127_10038245_1	1248917.ANFX01000029_gene2654	2.589e-44	162.0	COG1670@1|root,COG1670@2|Bacteria,1RK5M@1224|Proteobacteria,2UBIE@28211|Alphaproteobacteria,2K4T5@204457|Sphingomonadales	204457|Sphingomonadales	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH3_k127_10038245_0	629773.AORY01000002_gene1711	1.109e-100	341.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,2U2AF@28211|Alphaproteobacteria,2K116@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WH3_k127_10038245_2	450851.PHZ_c2188	7.858e-36	147.0	COG3279@1|root,COG3279@2|Bacteria,1R90R@1224|Proteobacteria,2UAG2@28211|Alphaproteobacteria,2KH5T@204458|Caulobacterales	204458|Caulobacterales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
WH3_k127_10055138_1	1248917.ANFX01000008_gene347	5.584e-136	435.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,2JZUG@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GIY-YIG,SpoU_methylase
WH3_k127_10055138_3	1248917.ANFX01000008_gene346	1.48e-91	301.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,2K3W4@204457|Sphingomonadales	204457|Sphingomonadales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WH3_k127_10055138_4	1248917.ANFX01000008_gene345	1.93e-28	116.0	2CK7K@1|root,301DG@2|Bacteria,1N7CB@1224|Proteobacteria,2UH47@28211|Alphaproteobacteria,2K78N@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10055138_0	1248917.ANFX01000008_gene344	3.844e-276	854.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria,2K0BB@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WH3_k127_10055138_2	1479239.JQMU01000001_gene2638	2.035e-97	320.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,2U94R@28211|Alphaproteobacteria,2K4KN@204457|Sphingomonadales	204457|Sphingomonadales	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WH3_k127_10055138_5	1479239.JQMU01000001_gene2639	2.486e-16	81.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,2K016@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH3_k127_10090308_0	1248917.ANFX01000013_gene1432	1.033e-222	696.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,2K02P@204457|Sphingomonadales	204457|Sphingomonadales	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WH3_k127_10090308_1	1248917.ANFX01000013_gene1431	3.852e-12	65.0	COG0352@1|root,COG0352@2|Bacteria,1RKGX@1224|Proteobacteria,2UB4W@28211|Alphaproteobacteria,2K57F@204457|Sphingomonadales	204457|Sphingomonadales	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
WH3_k127_10102320_2	1479239.JQMU01000001_gene2531	1.553e-06	52.0	COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,2TTK7@28211|Alphaproteobacteria,2K2EX@204457|Sphingomonadales	204457|Sphingomonadales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH3_k127_10102320_1	1479239.JQMU01000001_gene2530	5.824e-229	721.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TQWE@28211|Alphaproteobacteria,2K1JW@204457|Sphingomonadales	204457|Sphingomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WH3_k127_10102320_0	1479239.JQMU01000001_gene2529	7.657e-306	941.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TR00@28211|Alphaproteobacteria,2K2BN@204457|Sphingomonadales	204457|Sphingomonadales	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
WH3_k127_10105497_0	1479239.JQMU01000001_gene361	0.0	1340.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2K2HN@204457|Sphingomonadales	204457|Sphingomonadales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
WH3_k127_10105497_5	1479239.JQMU01000001_gene359	4.284e-98	326.0	COG0745@1|root,COG0745@2|Bacteria,1QU38@1224|Proteobacteria,2TVXD@28211|Alphaproteobacteria,2KAIR@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH3_k127_10105497_6	196490.AUEZ01000023_gene7145	1.279e-84	294.0	COG0671@1|root,COG0671@2|Bacteria,1MWK1@1224|Proteobacteria,2U0HJ@28211|Alphaproteobacteria,3JWVD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WH3_k127_10105497_2	1248917.ANFX01000009_gene233	1.356e-169	542.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,2K01W@204457|Sphingomonadales	204457|Sphingomonadales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WH3_k127_10105497_4	1248917.ANFX01000009_gene232	4.193e-119	386.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,2K1G1@204457|Sphingomonadales	204457|Sphingomonadales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WH3_k127_10105497_3	1479239.JQMU01000001_gene354	1.267e-140	453.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2K1QM@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WH3_k127_10105497_1	1479239.JQMU01000001_gene353	1.894e-290	898.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,2K0KU@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the GPI family	pgi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WH3_k127_10115189_9	1479239.JQMU01000001_gene1809	2.635e-55	199.0	2AMDQ@1|root,31C95@2|Bacteria,1P8HG@1224|Proteobacteria,2UX5A@28211|Alphaproteobacteria,2K7SX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10115189_8	1479239.JQMU01000001_gene1810	5.631e-100	328.0	COG1580@1|root,COG1580@2|Bacteria,1MYGB@1224|Proteobacteria,2UAY8@28211|Alphaproteobacteria,2K2E2@204457|Sphingomonadales	204457|Sphingomonadales	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
WH3_k127_10115189_3	1479239.JQMU01000001_gene1811	1.871e-145	468.0	COG1868@1|root,COG1868@2|Bacteria,1QAGH@1224|Proteobacteria,2UMVH@28211|Alphaproteobacteria,2K6C1@204457|Sphingomonadales	204457|Sphingomonadales	N	Type III flagellar switch regulator (C-ring) FliN C-term	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
WH3_k127_10115189_10	1479239.JQMU01000001_gene1812	1.959e-44	166.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2UHHH@28211|Alphaproteobacteria,2K5SF@204457|Sphingomonadales	204457|Sphingomonadales	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
WH3_k127_10115189_12	1479239.JQMU01000001_gene1813	1.353e-37	145.0	COG3190@1|root,COG3190@2|Bacteria,1N09F@1224|Proteobacteria,2UEGM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	Flagellar biogenesis protein	fliO	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
WH3_k127_10115189_6	1479239.JQMU01000001_gene1814	5.477e-124	402.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2TT93@28211|Alphaproteobacteria,2K12T@204457|Sphingomonadales	204457|Sphingomonadales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
WH3_k127_10115189_13	1479239.JQMU01000001_gene1815	2.54e-33	140.0	COG1987@1|root,COG1987@2|Bacteria,1Q2H4@1224|Proteobacteria,2UIHC@28211|Alphaproteobacteria,2KD9J@204457|Sphingomonadales	204457|Sphingomonadales	N	Bacterial export proteins, family 3	fliQ	-	-	-	-	-	-	-	-	-	-	-	Bac_export_3
WH3_k127_10115189_5	1479239.JQMU01000001_gene1816	2.072e-132	426.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2U4PM@28211|Alphaproteobacteria,2K205@204457|Sphingomonadales	204457|Sphingomonadales	N	Flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
WH3_k127_10115189_2	1479239.JQMU01000001_gene1817	1.334e-186	588.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2TS13@28211|Alphaproteobacteria,2K0RR@204457|Sphingomonadales	204457|Sphingomonadales	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
WH3_k127_10115189_1	1479239.JQMU01000001_gene1818	2.803e-212	668.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2TQNV@28211|Alphaproteobacteria,2K0ZT@204457|Sphingomonadales	204457|Sphingomonadales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
WH3_k127_10115189_11	1479239.JQMU01000001_gene1819	2.482e-41	155.0	COG1516@1|root,COG1516@2|Bacteria,1PNR2@1224|Proteobacteria,2V1AF@28211|Alphaproteobacteria,2KBAN@204457|Sphingomonadales	204457|Sphingomonadales	NOU	Flagellar protein FliS	-	-	-	-	-	-	-	-	-	-	-	-	FliS
WH3_k127_10115189_4	1248917.ANFX01000033_gene728	5.923e-143	467.0	COG0596@1|root,COG0596@2|Bacteria,1RD9Q@1224|Proteobacteria,2TW3W@28211|Alphaproteobacteria,2KEA4@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
WH3_k127_10115189_0	1479239.JQMU01000001_gene1821	1.983e-241	755.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,2U3NB@28211|Alphaproteobacteria,2K0X3@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
WH3_k127_10115189_7	1248917.ANFX01000033_gene725	3.309e-117	377.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,2K04T@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WH3_k127_10131669_1	1479239.JQMU01000001_gene1516	1.358e-119	387.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,2TUF8@28211|Alphaproteobacteria,2K6MZ@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
WH3_k127_10131669_5	237727.NAP1_11048	1.154e-64	228.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2UCM1@28211|Alphaproteobacteria,2K652@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Smr
WH3_k127_10131669_0	1479239.JQMU01000001_gene1669	3.998e-203	638.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,2K0IG@204457|Sphingomonadales	204457|Sphingomonadales	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
WH3_k127_10131669_2	1479239.JQMU01000001_gene1670	7.147e-114	370.0	COG4395@1|root,COG4395@2|Bacteria,1NCIX@1224|Proteobacteria,2TTDQ@28211|Alphaproteobacteria,2K0UG@204457|Sphingomonadales	204457|Sphingomonadales	S	import inner membrane translocase, subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
WH3_k127_10131669_3	1479239.JQMU01000001_gene1671	1.08e-99	329.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria,2K4QA@204457|Sphingomonadales	204457|Sphingomonadales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
WH3_k127_10131669_4	1122970.AUHC01000013_gene1098	3.326e-71	242.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,2K03M@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WH3_k127_10133352_2	1479239.JQMU01000001_gene2654	1.927e-53	189.0	COG1846@1|root,COG1846@2|Bacteria,1NYW3@1224|Proteobacteria,2UTVX@28211|Alphaproteobacteria,2K6HH@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
WH3_k127_10133352_0	1479239.JQMU01000001_gene2653	7.227e-253	801.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,2K00W@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WH3_k127_10133352_1	1248917.ANFX01000008_gene328	1.895e-77	266.0	2EJM3@1|root,33DC0@2|Bacteria,1NCX3@1224|Proteobacteria,2UFXE@28211|Alphaproteobacteria,2K6CI@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10133352_4	1479239.JQMU01000001_gene2651	5.811e-44	164.0	2AM8H@1|root,31C3B@2|Bacteria,1NP89@1224|Proteobacteria,2UN1P@28211|Alphaproteobacteria,2KDQZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10133352_5	1479239.JQMU01000001_gene2650	1.583e-40	153.0	2A9PK@1|root,30YWH@2|Bacteria,1P5WS@1224|Proteobacteria,2UWXG@28211|Alphaproteobacteria,2K8B1@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10133352_3	1479239.JQMU01000001_gene2649	5.203e-51	186.0	2A33G@1|root,30RIG@2|Bacteria,1Q84Q@1224|Proteobacteria,2V76M@28211|Alphaproteobacteria,2KAVC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10133352_6	1248917.ANFX01000008_gene332	1.699e-10	62.0	COG0483@1|root,COG0483@2|Bacteria,1N7D7@1224|Proteobacteria,2UF6T@28211|Alphaproteobacteria,2K5WG@204457|Sphingomonadales	204457|Sphingomonadales	G	Domain of unknown function (DUF4170)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4170
WH3_k127_10146145_5	383381.EH30_09460	5.344e-39	149.0	28X1J@1|root,2ZJ09@2|Bacteria,1N9NE@1224|Proteobacteria,2UHAN@28211|Alphaproteobacteria,2K63K@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10146145_4	1248917.ANFX01000051_gene454	1.119e-42	158.0	2B2V7@1|root,31VFS@2|Bacteria,1NBPZ@1224|Proteobacteria,2UGTR@28211|Alphaproteobacteria,2KCC5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10146145_2	1248917.ANFX01000051_gene453	1.297e-68	235.0	COG1983@1|root,COG1983@2|Bacteria,1RHXA@1224|Proteobacteria,2UA9Z@28211|Alphaproteobacteria,2K54F@204457|Sphingomonadales	204457|Sphingomonadales	KT	PspC domain	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
WH3_k127_10146145_3	1248917.ANFX01000051_gene452	5.538e-52	184.0	2EH78@1|root,33AZ2@2|Bacteria,1N7AP@1224|Proteobacteria,2UGJI@28211|Alphaproteobacteria,2K6SQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Phage shock protein B	pspB	-	-	ko:K03970	-	-	-	-	ko00000,ko02048	-	-	-	PspB
WH3_k127_10146145_1	1479239.JQMU01000001_gene2090	7.6e-159	507.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,2U6CN@28211|Alphaproteobacteria,2K2DP@204457|Sphingomonadales	204457|Sphingomonadales	KT	Phage shock protein A	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
WH3_k127_10146145_0	1479239.JQMU01000001_gene2092	3.071e-194	619.0	COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,2TR58@28211|Alphaproteobacteria,2K0CK@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
WH3_k127_10146145_7	1044.EH31_13255	1.983e-05	49.0	2AKDR@1|root,31B50@2|Bacteria,1Q6WN@1224|Proteobacteria,2VCZU@28211|Alphaproteobacteria,2KC3M@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10172193_0	1248917.ANFX01000032_gene864	3.797e-165	522.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,2K0AK@204457|Sphingomonadales	204457|Sphingomonadales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WH3_k127_10172193_1	1248917.ANFX01000032_gene865	9.228e-142	452.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,2TQJ6@28211|Alphaproteobacteria,2K2RN@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K18335	ko00051,ko01120,map00051,map01120	-	R10690	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WH3_k127_10172193_2	1122970.AUHC01000008_gene109	1.073e-60	213.0	COG5517@1|root,COG5517@2|Bacteria,1N622@1224|Proteobacteria,2UHQF@28211|Alphaproteobacteria,2KE5P@204457|Sphingomonadales	204457|Sphingomonadales	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
WH3_k127_10179186_5	1479239.JQMU01000001_gene1210	2.596e-13	69.0	COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,2UGGS@28211|Alphaproteobacteria,2KCA0@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
WH3_k127_10179186_1	1479239.JQMU01000001_gene1211	6.363e-248	777.0	COG5388@1|root,COG5388@2|Bacteria,1R74W@1224|Proteobacteria,2TUTW@28211|Alphaproteobacteria,2K1EC@204457|Sphingomonadales	204457|Sphingomonadales	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10179186_0	1479239.JQMU01000001_gene1212	1.105e-253	788.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,2K0E5@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16
WH3_k127_10179186_3	1248917.ANFX01000013_gene1524	2.989e-103	340.0	COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,2TTXR@28211|Alphaproteobacteria,2K3ZK@204457|Sphingomonadales	204457|Sphingomonadales	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
WH3_k127_10179186_2	1479239.JQMU01000001_gene1214	1.493e-163	520.0	COG0501@1|root,COG0501@2|Bacteria,1RH15@1224|Proteobacteria,2U9K7@28211|Alphaproteobacteria,2KCU5@204457|Sphingomonadales	204457|Sphingomonadales	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WH3_k127_10179186_4	1248917.ANFX01000013_gene1522	1.093e-95	314.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2JZWJ@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
WH3_k127_1021111_2	1479239.JQMU01000001_gene1847	1.3e-95	314.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,2K19R@204457|Sphingomonadales	204457|Sphingomonadales	GM	Dehydrogenase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
WH3_k127_1021111_1	1479239.JQMU01000001_gene1848	6.197e-145	464.0	COG0412@1|root,COG0412@2|Bacteria,1NRB4@1224|Proteobacteria,2TU91@28211|Alphaproteobacteria,2K272@204457|Sphingomonadales	204457|Sphingomonadales	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
WH3_k127_1021111_0	1479239.JQMU01000001_gene1849	0.0	1150.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales	204457|Sphingomonadales	CG	Dehydrogenase	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
WH3_k127_10311127_2	1248917.ANFX01000005_gene103	1.43e-37	143.0	COG3812@1|root,COG3812@2|Bacteria,1RCDT@1224|Proteobacteria,2U6UR@28211|Alphaproteobacteria,2K6G3@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1993
WH3_k127_10311127_0	1479239.JQMU01000001_gene1401	4.023e-309	951.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,2TRQ9@28211|Alphaproteobacteria,2K08Z@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
WH3_k127_10311127_3	1248917.ANFX01000005_gene101	6.962e-36	143.0	2EK15@1|root,33DRN@2|Bacteria,1N74W@1224|Proteobacteria,2UFQQ@28211|Alphaproteobacteria,2K6RJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10311127_1	1248917.ANFX01000005_gene100	3.655e-167	527.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,2TQU5@28211|Alphaproteobacteria,2K1G9@204457|Sphingomonadales	204457|Sphingomonadales	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B
WH3_k127_10409368_1	1479239.JQMU01000001_gene2510	9.121e-180	564.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,2JZUT@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
WH3_k127_10409368_0	1479239.JQMU01000001_gene2509	2.456e-283	873.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,2TU8S@28211|Alphaproteobacteria,2K13M@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	-	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
WH3_k127_10409368_4	1479239.JQMU01000001_gene2508	5.871e-77	264.0	2AKPD@1|root,31BG2@2|Bacteria,1NEKM@1224|Proteobacteria,2UHBC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10409368_2	1248917.ANFX01000037_gene2071	1.03e-151	484.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2TV8D@28211|Alphaproteobacteria,2K1SV@204457|Sphingomonadales	204457|Sphingomonadales	S	RarD protein	-	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
WH3_k127_10409368_3	1479239.JQMU01000001_gene2506	4.153e-103	336.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2TT2U@28211|Alphaproteobacteria,2K057@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WH3_k127_10413939_1	1248917.ANFX01000012_gene1796	2.952e-82	280.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2TSI7@28211|Alphaproteobacteria,2K1X1@204457|Sphingomonadales	204457|Sphingomonadales	O	cytochrome c biogenesis	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_11,TPR_14,TPR_16,TPR_2
WH3_k127_10413939_0	1479239.JQMU01000001_gene2208	1.265e-249	772.0	COG0492@1|root,COG0664@1|root,COG1142@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,COG1142@2|Bacteria,1QUPD@1224|Proteobacteria,2TW3N@28211|Alphaproteobacteria,2K28S@204457|Sphingomonadales	204457|Sphingomonadales	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7,Pyr_redox_2,Pyr_redox_3,cNMP_binding
WH3_k127_10427845_4	1248917.ANFX01000035_gene2001	9.3e-70	239.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,2U9FW@28211|Alphaproteobacteria,2K4F5@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
WH3_k127_10427845_0	1479239.JQMU01000001_gene1783	5.488e-233	725.0	COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,2TREN@28211|Alphaproteobacteria,2K01Q@204457|Sphingomonadales	204457|Sphingomonadales	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WH3_k127_10427845_3	1479239.JQMU01000001_gene1784	3.172e-79	269.0	2C2VU@1|root,34305@2|Bacteria,1N3B4@1224|Proteobacteria,2U9KX@28211|Alphaproteobacteria,2KDKP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10427845_1	1479239.JQMU01000001_gene1785	9.94e-191	599.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,2K1G3@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WH3_k127_10427845_5	1479239.JQMU01000001_gene1786	5.078e-16	79.0	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria,2UJAG@28211|Alphaproteobacteria,2K7QY@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WH3_k127_10427845_2	1479239.JQMU01000001_gene1787	5.726e-109	359.0	COG1011@1|root,COG1011@2|Bacteria,1RHAB@1224|Proteobacteria,2U7PV@28211|Alphaproteobacteria,2K2XU@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
WH3_k127_10429382_5	1479239.JQMU01000001_gene810	2.204e-167	530.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH3_k127_10429382_3	1479239.JQMU01000001_gene809	1.906e-213	666.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2TQQC@28211|Alphaproteobacteria,2K0C2@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WH3_k127_10429382_4	1479239.JQMU01000001_gene807	2.704e-202	632.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2TQYU@28211|Alphaproteobacteria,2K2VH@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
WH3_k127_10429382_6	1248917.ANFX01000032_gene1015	1.372e-117	380.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,2K49D@204457|Sphingomonadales	204457|Sphingomonadales	O	maleylacetoacetate isomerase	-	-	5.2.1.2	ko:K01800	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R03181	RC00867	ko00000,ko00001,ko00002,ko01000	-	-	-	GST_N,GST_N_3
WH3_k127_10429382_2	1479239.JQMU01000001_gene805	1.41e-248	770.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,2K030@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_10429382_9	1479239.JQMU01000001_gene804	6.148e-56	197.0	COG3947@1|root,COG3947@2|Bacteria,1QUNY@1224|Proteobacteria,2TW2H@28211|Alphaproteobacteria,2K64A@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH3_k127_10429382_7	1122970.AUHC01000014_gene1132	5.513e-57	203.0	COG3743@1|root,COG3743@2|Bacteria,1N76A@1224|Proteobacteria,2UEWG@28211|Alphaproteobacteria,2KD7I@204457|Sphingomonadales	204457|Sphingomonadales	S	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5
WH3_k127_10429382_0	1479239.JQMU01000001_gene802	6.839e-275	857.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,2TSQU@28211|Alphaproteobacteria,2K35S@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
WH3_k127_10429382_1	1479239.JQMU01000001_gene801	5.112e-273	848.0	COG2244@1|root,COG2244@2|Bacteria,1PDRG@1224|Proteobacteria,2TVKM@28211|Alphaproteobacteria,2K0P5@204457|Sphingomonadales	204457|Sphingomonadales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
WH3_k127_10429382_8	1479239.JQMU01000001_gene800	2.307e-56	198.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,2K0GB@204457|Sphingomonadales	204457|Sphingomonadales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WH3_k127_10436572_2	1248917.ANFX01000008_gene376	2.363e-63	219.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,2K18M@204457|Sphingomonadales	204457|Sphingomonadales	C	Dehydrogenase	-	-	1.1.2.3,1.1.99.31	ko:K00101,ko:K15054	ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120	-	R00196,R04160,R07664	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
WH3_k127_10436572_1	1479239.JQMU01000001_gene2609	2.057e-89	300.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2TVD3@28211|Alphaproteobacteria,2K26W@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WH3_k127_10436572_0	1479239.JQMU01000001_gene2610	2.054e-90	297.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,2JZWR@204457|Sphingomonadales	204457|Sphingomonadales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
WH3_k127_1044372_2	1248917.ANFX01000032_gene868	2.737e-40	149.0	COG5458@1|root,COG5458@2|Bacteria,1N054@1224|Proteobacteria,2UBY1@28211|Alphaproteobacteria,2K5VN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1489)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1489
WH3_k127_1044372_0	1479239.JQMU01000001_gene690	7.895e-152	492.0	COG5012@1|root,COG5012@2|Bacteria,1RJG2@1224|Proteobacteria	1224|Proteobacteria	S	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
WH3_k127_1044372_1	1479239.JQMU01000001_gene2521	2.507e-87	289.0	COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10449151_2	1479239.JQMU01000001_gene1070	7.947e-95	327.0	COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,2K43P@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
WH3_k127_10449151_0	1479239.JQMU01000001_gene1071	2.798e-140	447.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria,2JZVB@204457|Sphingomonadales	204457|Sphingomonadales	D	cell division	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WH3_k127_10449151_1	1479239.JQMU01000001_gene1072	2.392e-137	444.0	2E521@1|root,32ZVA@2|Bacteria,1RF95@1224|Proteobacteria,2U8QW@28211|Alphaproteobacteria,2K2DR@204457|Sphingomonadales	204457|Sphingomonadales	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
WH3_k127_10449383_0	1122970.AUHC01000002_gene1280	1.288e-120	395.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2TR7U@28211|Alphaproteobacteria,2KCMN@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0668 Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
WH3_k127_10449383_2	383381.EH30_12060	1.273e-50	182.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,2K539@204457|Sphingomonadales	204457|Sphingomonadales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WH3_k127_10449383_1	1248917.ANFX01000019_gene2403	1.409e-90	300.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,2K0H3@204457|Sphingomonadales	204457|Sphingomonadales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WH3_k127_10454166_2	1479239.JQMU01000001_gene2576	4.565e-160	507.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2TU0Q@28211|Alphaproteobacteria,2K0CD@204457|Sphingomonadales	204457|Sphingomonadales	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
WH3_k127_10454166_0	1479239.JQMU01000001_gene2577	1.873e-264	817.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,2TRKE@28211|Alphaproteobacteria,2K126@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_19,HTH_3,HTH_31,Peptidase_M78
WH3_k127_10454166_3	1248916.ANFY01000010_gene309	2.697e-65	226.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CaMKII_AD,DUF4440,SnoaL_2,SnoaL_3,SnoaL_4
WH3_k127_10454166_1	1248917.ANFX01000008_gene406	4.126e-241	749.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria,2K0H7@204457|Sphingomonadales	204457|Sphingomonadales	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WH3_k127_1047624_8	1479239.JQMU01000001_gene2169	2.225e-57	201.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,2K0Q0@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WH3_k127_1047624_5	1248917.ANFX01000013_gene1479	4.401e-76	261.0	COG5468@1|root,COG5468@2|Bacteria,1RKF8@1224|Proteobacteria,2UACI@28211|Alphaproteobacteria,2K4FJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Lipopolysaccharide-assembly	-	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
WH3_k127_1047624_1	1479239.JQMU01000001_gene2167	1.217e-184	586.0	COG1466@1|root,COG1466@2|Bacteria,1N7AB@1224|Proteobacteria,2UHPM@28211|Alphaproteobacteria,2K0ER@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WH3_k127_1047624_0	1479239.JQMU01000001_gene2166	2.509e-255	792.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria,2K10K@204457|Sphingomonadales	204457|Sphingomonadales	M	sugar transferase	spsB	-	-	ko:K20997	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Bac_transf
WH3_k127_1047624_7	1248917.ANFX01000013_gene1476	3.759e-70	243.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,2K3YP@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
WH3_k127_1047624_4	1479239.JQMU01000001_gene2164	1.449e-115	377.0	COG5375@1|root,COG5375@2|Bacteria,1NMV8@1224|Proteobacteria,2VCS4@28211|Alphaproteobacteria,2K34V@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein conserved in bacteria	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
WH3_k127_1047624_9	1479239.JQMU01000001_gene2163	4.68e-35	134.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,2K0FG@204457|Sphingomonadales	204457|Sphingomonadales	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
WH3_k127_1047624_6	1479239.JQMU01000001_gene2163	2.568e-72	256.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,2K0FG@204457|Sphingomonadales	204457|Sphingomonadales	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
WH3_k127_1047624_3	1248917.ANFX01000013_gene1473	2.105e-119	399.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2U1VI@28211|Alphaproteobacteria,2K0CQ@204457|Sphingomonadales	204457|Sphingomonadales	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WH3_k127_1047624_2	1248917.ANFX01000013_gene1472	1.511e-136	436.0	COG1024@1|root,COG1024@2|Bacteria,1N4N7@1224|Proteobacteria,2TS6T@28211|Alphaproteobacteria,2K1V0@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH3_k127_1047829_2	1156919.QWC_06114	3.926e-106	350.0	COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,2VYUM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	hydrolase of the alpha beta superfamily	yuiI	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
WH3_k127_1047829_0	1248917.ANFX01000037_gene2156	6.004e-137	439.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,2K1B1@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WH3_k127_1047829_3	1479239.JQMU01000001_gene481	1.712e-99	326.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria,2K00Z@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WH3_k127_1047829_1	1122970.AUHC01000009_gene279	2.641e-129	414.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,2K0JM@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WH3_k127_1047829_4	1479239.JQMU01000001_gene479	9.21e-32	124.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,2K1ET@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WH3_k127_10481032_7	1479239.JQMU01000001_gene667	1.241e-119	385.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria,2K0JX@204457|Sphingomonadales	204457|Sphingomonadales	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
WH3_k127_10481032_0	1479239.JQMU01000001_gene668	0.0	1655.0	COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,2K0RS@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WH3_k127_10481032_9	1248917.ANFX01000032_gene849	1.208e-110	359.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,2K0IN@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0694 Thioredoxin-like proteins and domains	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
WH3_k127_10481032_8	1479239.JQMU01000001_gene670	8.52e-113	370.0	COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria,2K16Z@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitroreductase family	-	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
WH3_k127_10481032_12	1248917.ANFX01000032_gene851	6.442e-84	283.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,2K59A@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M22	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M22
WH3_k127_10481032_15	1479239.JQMU01000001_gene672	1.15e-77	262.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,2K616@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
WH3_k127_10481032_16	1248917.ANFX01000032_gene853	2.39e-77	261.0	COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,2K4EY@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ROS_MUCR
WH3_k127_10481032_13	1479239.JQMU01000001_gene674	9.438e-84	280.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2U6ZS@28211|Alphaproteobacteria,2K3Z2@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WH3_k127_10481032_5	1479239.JQMU01000001_gene675	7.891e-163	518.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2TT8Q@28211|Alphaproteobacteria,2K221@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WH3_k127_10481032_3	1248917.ANFX01000032_gene856	4.721e-178	559.0	COG0583@1|root,COG0583@2|Bacteria,1R69A@1224|Proteobacteria,2U1WB@28211|Alphaproteobacteria,2K166@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
WH3_k127_10481032_4	1479239.JQMU01000001_gene677	6.043e-164	520.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,2K03F@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
WH3_k127_10481032_17	1248917.ANFX01000032_gene858	4.059e-75	257.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,2K4EE@204457|Sphingomonadales	204457|Sphingomonadales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
WH3_k127_10481032_14	1479239.JQMU01000001_gene625	1.132e-82	291.0	COG2271@1|root,COG2271@2|Bacteria,1R2YM@1224|Proteobacteria,2TZX8@28211|Alphaproteobacteria,2KBQH@204457|Sphingomonadales	1224|Proteobacteria	G	Acetyl-coenzyme A transporter 1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_10481032_6	1044.EH31_13420	8.442e-121	408.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K0BV@204457|Sphingomonadales	204457|Sphingomonadales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
WH3_k127_10481032_2	1479239.JQMU01000001_gene684	2.92e-209	654.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,2K21F@204457|Sphingomonadales	204457|Sphingomonadales	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
WH3_k127_10481032_1	1122970.AUHC01000008_gene113	1.131e-246	767.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,2K1NH@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WH3_k127_10481032_11	1479239.JQMU01000001_gene686	8.348e-94	309.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria,2K3YQ@204457|Sphingomonadales	204457|Sphingomonadales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
WH3_k127_10481032_10	1248917.ANFX01000032_gene864	1.809e-102	338.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,2K0AK@204457|Sphingomonadales	204457|Sphingomonadales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WH3_k127_10482395_1	1479239.JQMU01000001_gene2422	3.615e-158	506.0	COG2010@1|root,COG2010@2|Bacteria,1QUPA@1224|Proteobacteria,2U3YK@28211|Alphaproteobacteria,2K21S@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WH3_k127_10482395_0	1248917.ANFX01000038_gene592	7.192e-218	682.0	COG3420@1|root,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,2TTFV@28211|Alphaproteobacteria,2K0ZB@204457|Sphingomonadales	204457|Sphingomonadales	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
WH3_k127_10482395_3	1248917.ANFX01000038_gene591	3.467e-48	175.0	297IB@1|root,2ZURJ@2|Bacteria,1NA2F@1224|Proteobacteria,2UH54@28211|Alphaproteobacteria,2K7CH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10482395_2	1248917.ANFX01000038_gene590	1.548e-95	315.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,2K05C@204457|Sphingomonadales	204457|Sphingomonadales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
WH3_k127_10485488_7	1248917.ANFX01000007_gene36	1.138e-26	110.0	COG2311@1|root,COG2311@2|Bacteria,1MWHW@1224|Proteobacteria,2U3YJ@28211|Alphaproteobacteria,2KD2R@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
WH3_k127_10485488_5	1479239.JQMU01000001_gene1939	1.668e-138	449.0	COG0790@1|root,COG0790@2|Bacteria,1RJ71@1224|Proteobacteria,2U15P@28211|Alphaproteobacteria,2K032@204457|Sphingomonadales	204457|Sphingomonadales	S	FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
WH3_k127_10485488_4	1479239.JQMU01000001_gene1938	3.562e-143	456.0	COG1192@1|root,COG1192@2|Bacteria,1MWH3@1224|Proteobacteria,2U100@28211|Alphaproteobacteria,2K0JR@204457|Sphingomonadales	204457|Sphingomonadales	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WH3_k127_10485488_6	1479239.JQMU01000001_gene1937	2.699e-85	288.0	2BWQA@1|root,2ZWJK@2|Bacteria,1N8MW@1224|Proteobacteria,2UGCR@28211|Alphaproteobacteria,2K66S@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10485488_2	1479239.JQMU01000001_gene1936	7.72e-202	638.0	COG3087@1|root,COG5010@1|root,COG3087@2|Bacteria,COG5010@2|Bacteria,1RK9P@1224|Proteobacteria,2U5CI@28211|Alphaproteobacteria,2K119@204457|Sphingomonadales	204457|Sphingomonadales	U	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_16,TPR_19,TPR_4
WH3_k127_10485488_1	1479239.JQMU01000001_gene1935	3.844e-228	712.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2TSTM@28211|Alphaproteobacteria,2K003@204457|Sphingomonadales	204457|Sphingomonadales	F	dihydroorotase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WH3_k127_10485488_3	1479239.JQMU01000001_gene1934	2.168e-200	629.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2TRHP@28211|Alphaproteobacteria,2K0IH@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WH3_k127_10485488_0	1479239.JQMU01000001_gene1933	2.679e-308	954.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria,2K1TY@204457|Sphingomonadales	204457|Sphingomonadales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
WH3_k127_10492449_4	1248917.ANFX01000040_gene786	2.755e-197	616.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,2K0JK@204457|Sphingomonadales	204457|Sphingomonadales	E	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
WH3_k127_10492449_3	1479239.JQMU01000001_gene909	1.104e-201	635.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2UJRS@28211|Alphaproteobacteria,2K10F@204457|Sphingomonadales	204457|Sphingomonadales	E	Methionine synthase I (cobalamin-dependent), methyltransferase domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
WH3_k127_10492449_5	1479239.JQMU01000001_gene910	8.118e-190	595.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2TQZA@28211|Alphaproteobacteria,2K03Q@204457|Sphingomonadales	204457|Sphingomonadales	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
WH3_k127_10492449_6	1479239.JQMU01000001_gene911	4.637e-164	521.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria,2K0VB@204457|Sphingomonadales	204457|Sphingomonadales	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11
WH3_k127_10492449_2	1479239.JQMU01000001_gene914	1.841e-264	821.0	COG4146@1|root,COG4146@2|Bacteria,1MXWV@1224|Proteobacteria,2U1ED@28211|Alphaproteobacteria,2KDAS@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WH3_k127_10492449_1	1248917.ANFX01000040_gene793	0.0	1049.0	COG3345@1|root,COG3345@2|Bacteria,1MWTQ@1224|Proteobacteria,2TR2X@28211|Alphaproteobacteria,2K1XI@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
WH3_k127_10492449_0	1479239.JQMU01000001_gene916	0.0	1168.0	COG1874@1|root,COG1874@2|Bacteria,1MUVR@1224|Proteobacteria,2TTC5@28211|Alphaproteobacteria,2K27Y@204457|Sphingomonadales	204457|Sphingomonadales	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
WH3_k127_10492449_7	1248917.ANFX01000040_gene795	3.042e-135	436.0	COG0702@1|root,COG0702@2|Bacteria,1REY2@1224|Proteobacteria,2TS22@28211|Alphaproteobacteria,2K23H@204457|Sphingomonadales	204457|Sphingomonadales	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WH3_k127_10492449_8	1545915.JROG01000001_gene585	3.13e-25	113.0	2EGQ7@1|root,33AGD@2|Bacteria,1NI1N@1224|Proteobacteria,2UJJ3@28211|Alphaproteobacteria,2K5B7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10492449_9	383381.EH30_02145	6.565e-18	88.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_16,TPR_8,Trans_reg_C
WH3_k127_10527413_4	1479239.JQMU01000001_gene1634	1.438e-137	437.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria,2K04Q@204457|Sphingomonadales	204457|Sphingomonadales	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
WH3_k127_10527413_3	1479239.JQMU01000001_gene1635	2.334e-152	486.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,2K0FZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
WH3_k127_10527413_6	1248917.ANFX01000021_gene1657	1.121e-29	119.0	2BJAI@1|root,32DKD@2|Bacteria,1NJJ9@1224|Proteobacteria,2UK7D@28211|Alphaproteobacteria,2K7ZJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Hypoxia induced protein conserved region	-	-	-	-	-	-	-	-	-	-	-	-	HIG_1_N
WH3_k127_10527413_5	1248917.ANFX01000021_gene1658	5.294e-88	295.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,2K3VX@204457|Sphingomonadales	204457|Sphingomonadales	S	adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
WH3_k127_10527413_2	1479239.JQMU01000001_gene1638	4.756e-168	531.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria,2K0X2@204457|Sphingomonadales	204457|Sphingomonadales	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WH3_k127_10527413_0	1248917.ANFX01000021_gene1662	0.0	1516.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,2K09S@204457|Sphingomonadales	204457|Sphingomonadales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WH3_k127_10527413_1	1248917.ANFX01000021_gene1663	0.0	1216.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,2JZY4@204457|Sphingomonadales	204457|Sphingomonadales	C	Malic enzyme	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
WH3_k127_10562815_9	1479239.JQMU01000001_gene2465	3.106e-24	103.0	COG4221@1|root,COG4221@2|Bacteria,1QWIS@1224|Proteobacteria,2TSR3@28211|Alphaproteobacteria,2K3KB@204457|Sphingomonadales	204457|Sphingomonadales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH3_k127_10562815_6	1479239.JQMU01000001_gene2466	7.193e-71	244.0	COG1051@1|root,COG1051@2|Bacteria,1RH1H@1224|Proteobacteria,2UDQ3@28211|Alphaproteobacteria,2K4MF@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH3_k127_10562815_8	1248917.ANFX01000037_gene2029	3.885e-41	154.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2UF6U@28211|Alphaproteobacteria,2K60E@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
WH3_k127_10562815_4	1479239.JQMU01000001_gene2469	3.972e-106	351.0	COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria,2K4VC@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
WH3_k127_10562815_3	1248917.ANFX01000037_gene2032	1.516e-123	398.0	COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,2TS58@28211|Alphaproteobacteria,2K1M0@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
WH3_k127_10562815_2	1248917.ANFX01000037_gene2033	6.061e-164	520.0	COG3662@1|root,COG3662@2|Bacteria,1R50Q@1224|Proteobacteria,2TSG5@28211|Alphaproteobacteria,2K0BR@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
WH3_k127_10562815_1	1479239.JQMU01000001_gene2472	9.935e-200	623.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,2K0S6@204457|Sphingomonadales	204457|Sphingomonadales	S	Aerobic cobaltochelatase subunit CobS	-	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C,CobS_N
WH3_k127_10562815_0	1479239.JQMU01000001_gene2473	0.0	1235.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2K0XK@204457|Sphingomonadales	204457|Sphingomonadales	M	Penicillin-binding Protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WH3_k127_10562815_7	1479239.JQMU01000001_gene2474	2.254e-63	219.0	COG2050@1|root,COG2050@2|Bacteria,1RITB@1224|Proteobacteria,2U58S@28211|Alphaproteobacteria,2K6CX@204457|Sphingomonadales	204457|Sphingomonadales	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT,4HBT_3
WH3_k127_10562815_5	1479239.JQMU01000001_gene2475	1.702e-94	315.0	COG2050@1|root,COG2050@2|Bacteria,1RHK6@1224|Proteobacteria,2U72Z@28211|Alphaproteobacteria,2K530@204457|Sphingomonadales	204457|Sphingomonadales	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH3_k127_10562815_10	1122970.AUHC01000005_gene1876	3.719e-13	74.0	COG1413@1|root,COG1413@2|Bacteria,1NNZF@1224|Proteobacteria,2UHZP@28211|Alphaproteobacteria,2K76E@204457|Sphingomonadales	204457|Sphingomonadales	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10563913_3	1479239.JQMU01000001_gene219	3.006e-25	105.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,2K0WH@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
WH3_k127_10563913_1	1122970.AUHC01000001_gene731	1.818e-102	346.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria,2K3ZM@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WH3_k127_10563913_2	1122612.AUBA01000009_gene2135	1.382e-65	239.0	COG0454@1|root,COG0456@2|Bacteria,1Q5AK@1224|Proteobacteria,2TUP8@28211|Alphaproteobacteria,2K3K5@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,MarR_2
WH3_k127_10563913_0	1479239.JQMU01000001_gene223	8.097e-194	605.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,2K0KT@204457|Sphingomonadales	204457|Sphingomonadales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WH3_k127_10611496_0	1479239.JQMU01000001_gene2517	4.173e-295	906.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,2K1IW@204457|Sphingomonadales	204457|Sphingomonadales	H	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
WH3_k127_10611496_3	1248917.ANFX01000037_gene2081	3.474e-198	633.0	COG4995@1|root,COG4995@2|Bacteria,1PF01@1224|Proteobacteria,2U6BX@28211|Alphaproteobacteria,2K47V@204457|Sphingomonadales	204457|Sphingomonadales	M	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
WH3_k127_10611496_8	1479239.JQMU01000001_gene2516	1.608e-45	166.0	COG1359@1|root,COG1359@2|Bacteria,1N8V7@1224|Proteobacteria,2UFYD@28211|Alphaproteobacteria,2K761@204457|Sphingomonadales	204457|Sphingomonadales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WH3_k127_10611496_2	1479239.JQMU01000001_gene2515	2.517e-255	792.0	COG2020@1|root,COG2020@2|Bacteria,1R55E@1224|Proteobacteria,2U75X@28211|Alphaproteobacteria,2K0AU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein-S-isoprenylcysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295,ICMT
WH3_k127_10611496_1	1479239.JQMU01000001_gene2514	4.223e-257	798.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,2K0GW@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
WH3_k127_10611496_6	1479239.JQMU01000001_gene2513	4.228e-120	391.0	COG4649@1|root,COG4649@2|Bacteria,1P2GI@1224|Proteobacteria,2UCFZ@28211|Alphaproteobacteria,2K40C@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
WH3_k127_10611496_4	1479239.JQMU01000001_gene2512	1.307e-187	596.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2U43G@28211|Alphaproteobacteria,2K0KR@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH3_k127_10611496_5	1479239.JQMU01000001_gene2511	2.685e-159	505.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria,2K14Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WH3_k127_10611496_7	1479239.JQMU01000001_gene2510	2.149e-109	357.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,2JZUT@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
WH3_k127_10615138_2	1122970.AUHC01000002_gene1449	3.457e-183	576.0	COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,2TUDJ@28211|Alphaproteobacteria,2JZUY@204457|Sphingomonadales	204457|Sphingomonadales	I	3-phytase	phy	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
WH3_k127_10615138_0	1479239.JQMU01000001_gene877	3.745e-254	789.0	COG3211@1|root,COG3211@2|Bacteria,1Q4XN@1224|Proteobacteria,2VBCD@28211|Alphaproteobacteria,2JZXD@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
WH3_k127_10615138_5	1479239.JQMU01000001_gene876	6.288e-71	244.0	COG2119@1|root,COG2119@2|Bacteria,1NSQU@1224|Proteobacteria,2USV0@28211|Alphaproteobacteria,2K76S@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
WH3_k127_10615138_3	1479239.JQMU01000001_gene874	1.011e-103	340.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2U5C7@28211|Alphaproteobacteria,2JZZT@204457|Sphingomonadales	204457|Sphingomonadales	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
WH3_k127_10615138_4	1479239.JQMU01000001_gene873	2.336e-81	273.0	COG1051@1|root,COG1051@2|Bacteria,1N86M@1224|Proteobacteria,2VE53@28211|Alphaproteobacteria,2K6YD@204457|Sphingomonadales	204457|Sphingomonadales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH3_k127_10615138_1	1479239.JQMU01000001_gene872	1.071e-197	623.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,2K1Q4@204457|Sphingomonadales	204457|Sphingomonadales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WH3_k127_10615138_6	1248917.ANFX01000045_gene1293	2.842e-25	107.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,2K0JH@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
WH3_k127_10620314_1	1479239.JQMU01000001_gene1158	6.166e-11	65.0	COG2199@1|root,COG3706@2|Bacteria,1MW39@1224|Proteobacteria,2U25F@28211|Alphaproteobacteria,2KDVH@204457|Sphingomonadales	204457|Sphingomonadales	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
WH3_k127_10620314_0	1479239.JQMU01000001_gene1157	3.699e-190	598.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,2K0M7@204457|Sphingomonadales	204457|Sphingomonadales	P	Phosphate ABC transporter substrate-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WH3_k127_10631223_3	1479239.JQMU01000001_gene1981	5.929e-67	229.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,2K12E@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WH3_k127_10631223_1	1479239.JQMU01000001_gene1982	5.53e-84	286.0	COG3218@1|root,COG3218@2|Bacteria,1RKTW@1224|Proteobacteria,2UIN8@28211|Alphaproteobacteria,2KCCN@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
WH3_k127_10631223_0	1479239.JQMU01000001_gene1983	1.959e-114	372.0	COG5387@1|root,COG5387@2|Bacteria,1Q3B5@1224|Proteobacteria,2TVK1@28211|Alphaproteobacteria,2K1FD@204457|Sphingomonadales	204457|Sphingomonadales	O	Chaperone required for the assembly of the mitochondrial F1-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ATP12
WH3_k127_10631223_4	1479239.JQMU01000001_gene1984	1.962e-22	104.0	2ABNC@1|root,31146@2|Bacteria,1PP74@1224|Proteobacteria,2V1Q9@28211|Alphaproteobacteria,2KBVJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10631223_2	1479239.JQMU01000001_gene1985	1.012e-80	271.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2U703@28211|Alphaproteobacteria,2K3XQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WH3_k127_1072913_4	1479239.JQMU01000001_gene1480	3.758e-42	160.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria,2K4FF@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
WH3_k127_1072913_1	1479239.JQMU01000001_gene1479	1.947e-83	279.0	COG0454@1|root,COG0456@2|Bacteria,1RH71@1224|Proteobacteria,2UB0M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WH3_k127_1072913_2	1479239.JQMU01000001_gene1478	4.401e-76	261.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,2K4IC@204457|Sphingomonadales	204457|Sphingomonadales	S	FeS assembly SUF system protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
WH3_k127_1072913_0	1479239.JQMU01000001_gene1477	9.978e-229	715.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TRNY@28211|Alphaproteobacteria,2JZVI@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
WH3_k127_1072913_3	1248917.ANFX01000013_gene1498	3.064e-50	179.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,2K20T@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
WH3_k127_10741858_0	1479239.JQMU01000001_gene303	1.149e-305	941.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,2K1MX@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WH3_k127_10741858_1	1248917.ANFX01000024_gene1163	6.886e-42	156.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,2K035@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
WH3_k127_1081375_4	1479239.JQMU01000001_gene2145	1.013e-86	289.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U7XJ@28211|Alphaproteobacteria,2KD75@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
WH3_k127_1081375_3	1479239.JQMU01000001_gene2147	2.699e-99	326.0	COG0484@1|root,COG0484@2|Bacteria,1RASJ@1224|Proteobacteria,2U5FR@28211|Alphaproteobacteria,2K3W9@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
WH3_k127_1081375_2	1248917.ANFX01000020_gene2226	1.559e-165	528.0	COG4221@1|root,COG4221@2|Bacteria,1NTNU@1224|Proteobacteria,2TY9X@28211|Alphaproteobacteria,2KDN0@204457|Sphingomonadales	204457|Sphingomonadales	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH3_k127_1081375_0	1479239.JQMU01000001_gene2149	1.515e-267	826.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,2K1W3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
WH3_k127_1081375_1	1479239.JQMU01000001_gene2150	3.028e-237	741.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2TU0C@28211|Alphaproteobacteria,2K329@204457|Sphingomonadales	204457|Sphingomonadales	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
WH3_k127_10850254_1	1248917.ANFX01000037_gene2025	1.289e-180	568.0	COG4427@1|root,COG4427@2|Bacteria,1R4EV@1224|Proteobacteria,2TRVP@28211|Alphaproteobacteria,2K05T@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
WH3_k127_10850254_0	1479239.JQMU01000001_gene2464	8.701e-186	584.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,2TS7X@28211|Alphaproteobacteria,2KEG6@204457|Sphingomonadales	204457|Sphingomonadales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WH3_k127_10850254_2	1479239.JQMU01000001_gene2465	4.501e-77	259.0	COG4221@1|root,COG4221@2|Bacteria,1QWIS@1224|Proteobacteria,2TSR3@28211|Alphaproteobacteria,2K3KB@204457|Sphingomonadales	204457|Sphingomonadales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH3_k127_10908817_0	1479239.JQMU01000001_gene861	2.354e-294	903.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2TS0S@28211|Alphaproteobacteria,2JZYN@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
WH3_k127_10908817_1	1545915.JROG01000009_gene2855	1.293e-20	97.0	2FGHN@1|root,348DJ@2|Bacteria,1NT1T@1224|Proteobacteria,2UQJG@28211|Alphaproteobacteria,2K9QF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10936248_3	383381.EH30_15470	1.007e-85	284.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2TSQ0@28211|Alphaproteobacteria,2K06W@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WH3_k127_10936248_2	1479239.JQMU01000001_gene1333	1.153e-89	297.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,2K3Z8@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WH3_k127_10936248_0	1479239.JQMU01000001_gene1334	7.393e-199	628.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,2K0ZI@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
WH3_k127_10936248_4	1479239.JQMU01000001_gene1335	1.426e-72	257.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria,2K4ET@204457|Sphingomonadales	204457|Sphingomonadales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
WH3_k127_10936248_1	1479239.JQMU01000001_gene1336	2.221e-163	518.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,2K0M2@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WH3_k127_10944855_4	1248917.ANFX01000019_gene2347	1.126e-08	64.0	COG0346@1|root,COG0346@2|Bacteria,1RKHN@1224|Proteobacteria,2UBJ1@28211|Alphaproteobacteria,2K57E@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
WH3_k127_10944855_0	1479239.JQMU01000001_gene1588	2.34e-319	981.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K1MV@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_10944855_3	1122970.AUHC01000011_gene2684	1.682e-72	245.0	COG2050@1|root,COG2050@2|Bacteria,1N180@1224|Proteobacteria,2UCK4@28211|Alphaproteobacteria,2K7XG@204457|Sphingomonadales	204457|Sphingomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH3_k127_10944855_2	1248917.ANFX01000019_gene2350	7.122e-109	354.0	COG5517@1|root,COG5517@2|Bacteria,1Q85G@1224|Proteobacteria,2UVD7@28211|Alphaproteobacteria,2K78T@204457|Sphingomonadales	204457|Sphingomonadales	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
WH3_k127_10944855_1	1479239.JQMU01000001_gene1591	3.293e-194	608.0	COG2130@1|root,COG2130@2|Bacteria,1MZ3F@1224|Proteobacteria,2U37Z@28211|Alphaproteobacteria,2K157@204457|Sphingomonadales	204457|Sphingomonadales	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
WH3_k127_10969824_1	1248917.ANFX01000031_gene2574	4.777e-11	63.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,2JZYY@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WH3_k127_10969824_0	1479239.JQMU01000001_gene2812	0.0	995.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,2K16X@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
WH3_k127_10977069_1	1479239.JQMU01000001_gene743	4.895e-48	171.0	COG1403@1|root,COG1403@2|Bacteria,1MZVF@1224|Proteobacteria,2UBUF@28211|Alphaproteobacteria,2K5ZU@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_10977069_2	1479239.JQMU01000001_gene741	3.758e-36	138.0	2BR1N@1|root,32JZ6@2|Bacteria,1Q2J6@1224|Proteobacteria,2V9VN@28211|Alphaproteobacteria,2KB6X@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1153
WH3_k127_10977069_0	1479239.JQMU01000001_gene740	0.0	1296.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TTAX@28211|Alphaproteobacteria,2KDD3@204457|Sphingomonadales	204457|Sphingomonadales	E	COG1505 Serine proteases of the peptidase family S9A	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WH3_k127_10977069_3	1479239.JQMU01000001_gene739	1.843e-28	114.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,2K5WN@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02113,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
WH3_k127_10998117_0	1122970.AUHC01000004_gene2294	0.0	1458.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MX4K@1224|Proteobacteria,2TV3K@28211|Alphaproteobacteria,2JZXE@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_10998117_2	1479239.JQMU01000001_gene2051	3.792e-137	439.0	COG0745@1|root,COG0745@2|Bacteria,1NR4N@1224|Proteobacteria,2UPPS@28211|Alphaproteobacteria,2K4BM@204457|Sphingomonadales	204457|Sphingomonadales	T	Regulator	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH3_k127_10998117_1	1479239.JQMU01000001_gene2050	2.045e-191	600.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,2K1KY@204457|Sphingomonadales	204457|Sphingomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH3_k127_10998117_3	1479239.JQMU01000001_gene2049	8.849e-64	219.0	COG1028@1|root,COG1028@2|Bacteria,1MXQR@1224|Proteobacteria,2TW65@28211|Alphaproteobacteria,2K05S@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH3_k127_11022151_0	1248917.ANFX01000035_gene1967	2.103e-245	760.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2TR5F@28211|Alphaproteobacteria,2K04J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wecC	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH3_k127_11022151_1	1248917.ANFX01000035_gene1966	2.665e-203	639.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2TTGZ@28211|Alphaproteobacteria,2K0V2@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
WH3_k127_11027254_0	1248917.ANFX01000014_gene1392	9.302e-177	560.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,2K0U9@204457|Sphingomonadales	204457|Sphingomonadales	I	poly(R)-hydroxyalkanoic acid synthase	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
WH3_k127_11027254_1	1479239.JQMU01000001_gene928	1.065e-105	343.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria,2K0GY@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_11069012_3	1248917.ANFX01000007_gene27	5.364e-186	583.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2TS3R@28211|Alphaproteobacteria,2JZWY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WH3_k127_11069012_4	1248917.ANFX01000007_gene28	1.173e-138	443.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,2JZX6@204457|Sphingomonadales	204457|Sphingomonadales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WH3_k127_11069012_2	1479239.JQMU01000001_gene1949	8.042e-247	773.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,2K0M0@204457|Sphingomonadales	204457|Sphingomonadales	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
WH3_k127_11069012_1	1479239.JQMU01000001_gene1948	5.491e-262	816.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,2K02U@204457|Sphingomonadales	204457|Sphingomonadales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WH3_k127_11069012_10	1225184.ALXE01000021_gene2521	5.539e-07	52.0	2EFWG@1|root,339NR@2|Bacteria,1NIWH@1224|Proteobacteria,1SHRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11069012_7	1248917.ANFX01000007_gene31	2.469e-56	199.0	2CC0C@1|root,32RUG@2|Bacteria,1MZVQ@1224|Proteobacteria,2UBWU@28211|Alphaproteobacteria,2K606@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3297)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3297
WH3_k127_11069012_0	1248917.ANFX01000007_gene32	4.402e-277	856.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,2K0SQ@204457|Sphingomonadales	204457|Sphingomonadales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WH3_k127_11069012_6	1248917.ANFX01000007_gene33	3.986e-70	241.0	2E3B5@1|root,32YAP@2|Bacteria,1PK8M@1224|Proteobacteria,2UFEB@28211|Alphaproteobacteria,2K6NF@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
WH3_k127_11069012_5	1248917.ANFX01000007_gene34	7.478e-97	317.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2U70I@28211|Alphaproteobacteria,2K3XA@204457|Sphingomonadales	204457|Sphingomonadales	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
WH3_k127_11069012_8	1248917.ANFX01000007_gene35	4.672e-28	119.0	COG2906@1|root,COG2906@2|Bacteria,1PBPB@1224|Proteobacteria,2UM95@28211|Alphaproteobacteria,2K7VS@204457|Sphingomonadales	204457|Sphingomonadales	P	BFD-like [2Fe-2S] binding domain	-	-	-	ko:K02192	-	-	-	-	ko00000	-	-	-	Fer2_BFD
WH3_k127_11069012_9	314225.ELI_01065	1.471e-22	97.0	COG2311@1|root,COG2311@2|Bacteria,1MWHW@1224|Proteobacteria,2U310@28211|Alphaproteobacteria,2K0I8@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
WH3_k127_11082675_2	1248917.ANFX01000011_gene192	3.908e-135	433.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2TRVI@28211|Alphaproteobacteria,2K2C1@204457|Sphingomonadales	204457|Sphingomonadales	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
WH3_k127_11082675_3	1479239.JQMU01000001_gene530	2.526e-94	312.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,2K3YM@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WH3_k127_11082675_4	1248917.ANFX01000011_gene194	4.731e-90	303.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2UB7Z@28211|Alphaproteobacteria,2K526@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
WH3_k127_11082675_0	1479239.JQMU01000001_gene528	0.0	1405.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K0WG@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,Response_reg
WH3_k127_11082675_1	1479239.JQMU01000001_gene527	2.189e-210	656.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2K1TR@204457|Sphingomonadales	204457|Sphingomonadales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WH3_k127_11082675_5	1479239.JQMU01000001_gene526	1.517e-67	234.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,2K28K@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WH3_k127_11083104_2	1479239.JQMU01000001_gene2202	1.481e-162	516.0	COG3193@1|root,COG3193@2|Bacteria,1R3RC@1224|Proteobacteria,2U39K@28211|Alphaproteobacteria,2K2UI@204457|Sphingomonadales	204457|Sphingomonadales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
WH3_k127_11083104_1	1479239.JQMU01000001_gene2203	0.0	1171.0	COG3827@1|root,COG3827@2|Bacteria,1QQR0@1224|Proteobacteria,2U38X@28211|Alphaproteobacteria,2K2AW@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11083104_0	1479239.JQMU01000001_gene2204	0.0	1315.0	COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,2U4DF@28211|Alphaproteobacteria,2K18I@204457|Sphingomonadales	204457|Sphingomonadales	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WH3_k127_11083104_3	1479239.JQMU01000001_gene2204	1.112e-25	106.0	COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,2U4DF@28211|Alphaproteobacteria,2K18I@204457|Sphingomonadales	204457|Sphingomonadales	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WH3_k127_11162435_5	1479239.JQMU01000001_gene1433	1.906e-20	91.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,2K1U1@204457|Sphingomonadales	204457|Sphingomonadales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
WH3_k127_11162435_2	1248917.ANFX01000005_gene141	1.408e-94	312.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,2K3YB@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WH3_k127_11162435_0	1479239.JQMU01000001_gene1435	3.988e-125	404.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,2K06H@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
WH3_k127_11162435_1	1479239.JQMU01000001_gene1436	2.432e-102	335.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria,2K2CA@204457|Sphingomonadales	204457|Sphingomonadales	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
WH3_k127_11162435_4	1479239.JQMU01000001_gene1437	1.954e-74	257.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,2K6E5@204457|Sphingomonadales	204457|Sphingomonadales	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
WH3_k127_11162435_3	1479239.JQMU01000001_gene1438	2.088e-82	275.0	COG2050@1|root,COG2050@2|Bacteria,1RKWS@1224|Proteobacteria,2U9YA@28211|Alphaproteobacteria,2KE49@204457|Sphingomonadales	204457|Sphingomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH3_k127_11176294_3	395494.Galf_0626	8.133e-91	300.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,44VAW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WH3_k127_11176294_1	237727.NAP1_07175	6.56e-130	422.0	2ASJY@1|root,31I0J@2|Bacteria,1N0AE@1224|Proteobacteria,2UCJQ@28211|Alphaproteobacteria,2K162@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11176294_2	1479239.JQMU01000001_gene552	1.426e-109	361.0	COG1120@1|root,COG1120@2|Bacteria,1QPWJ@1224|Proteobacteria,2U1TK@28211|Alphaproteobacteria,2K1EJ@204457|Sphingomonadales	204457|Sphingomonadales	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WH3_k127_11176294_0	1479239.JQMU01000001_gene553	1.359e-168	534.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,2K0DB@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WH3_k127_11180575_3	1248917.ANFX01000016_gene2493	2.781e-66	227.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2TTKE@28211|Alphaproteobacteria,2JZZ7@204457|Sphingomonadales	204457|Sphingomonadales	E	Tryptophan halogenase	-	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
WH3_k127_11180575_4	1479239.JQMU01000001_gene2004	4.656e-63	230.0	COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,2K4M2@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
WH3_k127_11180575_0	1479239.JQMU01000001_gene2003	2.005e-122	397.0	COG4446@1|root,COG4446@2|Bacteria,1NXCA@1224|Proteobacteria,2UTDX@28211|Alphaproteobacteria,2K7M3@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
WH3_k127_11180575_2	1479239.JQMU01000001_gene2002	2.069e-97	321.0	COG0558@1|root,COG0558@2|Bacteria,1RD5Y@1224|Proteobacteria,2U8F4@28211|Alphaproteobacteria,2K40U@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
WH3_k127_11180575_1	1479239.JQMU01000001_gene2001	7.076e-120	387.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,2K07T@204457|Sphingomonadales	204457|Sphingomonadales	F	nucleoside	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Nucleos_tra2_C,Nucleos_tra2_N
WH3_k127_11194342_8	1122970.AUHC01000012_gene969	9.251e-36	136.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria,2K00I@204457|Sphingomonadales	204457|Sphingomonadales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
WH3_k127_11194342_7	1479239.JQMU01000001_gene1705	6.581e-42	158.0	COG3951@1|root,COG3951@2|Bacteria,1NG9S@1224|Proteobacteria,2UJMF@28211|Alphaproteobacteria,2K7KR@204457|Sphingomonadales	204457|Sphingomonadales	MNO	Rod binding protein	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Rod-binding
WH3_k127_11194342_1	1479239.JQMU01000001_gene1704	1.06e-220	691.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2U2HH@28211|Alphaproteobacteria,2K1JD@204457|Sphingomonadales	204457|Sphingomonadales	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WH3_k127_11194342_4	1479239.JQMU01000001_gene1703	4.067e-143	459.0	COG1344@1|root,COG1344@2|Bacteria,1N6F9@1224|Proteobacteria,2UEYK@28211|Alphaproteobacteria,2KDIB@204457|Sphingomonadales	204457|Sphingomonadales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WH3_k127_11194342_2	1248917.ANFX01000033_gene732	2.556e-168	530.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2TR5A@28211|Alphaproteobacteria,2K1GC@204457|Sphingomonadales	204457|Sphingomonadales	N	With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
WH3_k127_11194342_3	1122970.AUHC01000012_gene964	2.059e-159	506.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2TTW2@28211|Alphaproteobacteria,2JZXH@204457|Sphingomonadales	204457|Sphingomonadales	N	Flagellar motor protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
WH3_k127_11194342_0	1479239.JQMU01000001_gene2078	0.0	1096.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,2K1B4@204457|Sphingomonadales	204457|Sphingomonadales	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
WH3_k127_11194342_5	1122970.AUHC01000002_gene1335	4.738e-129	418.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2TT8X@28211|Alphaproteobacteria,2K02D@204457|Sphingomonadales	204457|Sphingomonadales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WH3_k127_11194342_6	1479239.JQMU01000001_gene1802	7.043e-94	314.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2TW3X@28211|Alphaproteobacteria,2K247@204457|Sphingomonadales	204457|Sphingomonadales	KT	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flrC	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Sigma54_activat
WH3_k127_11233075_1	1248917.ANFX01000033_gene748	4.838e-113	365.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2TV1G@28211|Alphaproteobacteria,2K2KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
WH3_k127_11233075_0	1479239.JQMU01000001_gene1501	0.0	1163.0	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,2TW3Y@28211|Alphaproteobacteria,2KEA5@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_11233075_2	1347086.CCBA010000012_gene2030	2.885e-08	56.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11259394_4	383381.EH30_08375	5.367e-06	48.0	COG5458@1|root,COG5458@2|Bacteria,1N054@1224|Proteobacteria,2UBY1@28211|Alphaproteobacteria,2K5VN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1489)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1489
WH3_k127_11259394_2	1292034.OR37_00825	1.051e-46	177.0	2919Q@1|root,3323P@2|Bacteria,1R3DN@1224|Proteobacteria,2U016@28211|Alphaproteobacteria,2KJ7E@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11259394_1	1248917.ANFX01000032_gene868	3.656e-71	242.0	COG5458@1|root,COG5458@2|Bacteria,1N054@1224|Proteobacteria,2UBY1@28211|Alphaproteobacteria,2K5VN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1489)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1489
WH3_k127_11259394_0	1248917.ANFX01000032_gene867	1.051e-294	906.0	COG4638@1|root,COG4638@2|Bacteria,1R56V@1224|Proteobacteria,2TTP0@28211|Alphaproteobacteria,2K21D@204457|Sphingomonadales	204457|Sphingomonadales	P	PFAM Rieske 2Fe-2S domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
WH3_k127_11259394_3	1248917.ANFX01000032_gene866	1.046e-42	156.0	COG5517@1|root,COG5517@2|Bacteria,1N622@1224|Proteobacteria,2UHQF@28211|Alphaproteobacteria,2KE5P@204457|Sphingomonadales	204457|Sphingomonadales	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
WH3_k127_11276780_2	1479239.JQMU01000001_gene2612	4.716e-94	308.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2K0GG@204457|Sphingomonadales	204457|Sphingomonadales	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WH3_k127_11276780_1	1479239.JQMU01000001_gene2611	7.284e-99	325.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2U5CW@28211|Alphaproteobacteria,2K12R@204457|Sphingomonadales	204457|Sphingomonadales	E	acetolactate synthase	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
WH3_k127_11276780_0	1248917.ANFX01000008_gene374	7.919e-130	423.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,2JZWR@204457|Sphingomonadales	204457|Sphingomonadales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
WH3_k127_11279817_2	1123270.ATUR01000002_gene2507	1.348e-56	204.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,2K4PP@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
WH3_k127_11279817_0	1479239.JQMU01000001_gene336	3.024e-198	621.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2K0HR@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
WH3_k127_11279817_1	1479239.JQMU01000001_gene337	2.854e-157	497.0	COG1878@1|root,COG1878@2|Bacteria,1MV8S@1224|Proteobacteria,2TSUJ@28211|Alphaproteobacteria,2K01S@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
WH3_k127_11279817_3	1248917.ANFX01000024_gene1136	6.662e-32	128.0	COG0454@1|root,COG0456@2|Bacteria,1RHB3@1224|Proteobacteria,2U70A@28211|Alphaproteobacteria,2K557@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) family	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
WH3_k127_11282530_1	1248917.ANFX01000008_gene290	3.766e-85	285.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TWH9@28211|Alphaproteobacteria,2KEEK@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
WH3_k127_11282530_2	1479239.JQMU01000001_gene2686	5.33e-59	207.0	2AI3K@1|root,318HD@2|Bacteria,1N501@1224|Proteobacteria,2UIA7@28211|Alphaproteobacteria,2K6EP@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WH3_k127_11282530_0	1479239.JQMU01000001_gene2687	1.138e-186	586.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria,2K11C@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WH3_k127_11312485_0	1479239.JQMU01000001_gene564	7.937e-188	598.0	2EB2V@1|root,3353M@2|Bacteria,1QED4@1224|Proteobacteria,2U3RZ@28211|Alphaproteobacteria,2K1M2@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
WH3_k127_11372509_5	1122970.AUHC01000009_gene240	2.246e-84	287.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2TW4K@28211|Alphaproteobacteria,2K1ZY@204457|Sphingomonadales	204457|Sphingomonadales	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
WH3_k127_11372509_0	1122970.AUHC01000009_gene239	0.0	1452.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,2K2A2@204457|Sphingomonadales	204457|Sphingomonadales	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
WH3_k127_11372509_1	1122970.AUHC01000009_gene238	0.0	1350.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2TR5K@28211|Alphaproteobacteria,2K1ND@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
WH3_k127_11372509_3	1122970.AUHC01000009_gene237	5.509e-247	768.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2TR6D@28211|Alphaproteobacteria,2K0QP@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH3_k127_11372509_4	279238.Saro_1656	2.115e-219	689.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2TT73@28211|Alphaproteobacteria,2K0QZ@204457|Sphingomonadales	204457|Sphingomonadales	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WH3_k127_11372509_2	1122970.AUHC01000009_gene235	3.63e-283	876.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2TRUJ@28211|Alphaproteobacteria,2K2CM@204457|Sphingomonadales	204457|Sphingomonadales	G	Phosphoglucomutase	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH3_k127_11372509_6	1122970.AUHC01000009_gene234	2.173e-75	258.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2TRVS@28211|Alphaproteobacteria,2K20M@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glycosyl hydrolase 13 family	glgX_2	-	3.2.1.196	ko:K02438	ko00500,ko01100,map00500,map01100	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
WH3_k127_11402479_4	1479239.JQMU01000001_gene1077	6.134e-21	96.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2K2YY@204457|Sphingomonadales	28211|Alphaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11402479_2	1479239.JQMU01000001_gene1076	1.533e-231	721.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,2TUMS@28211|Alphaproteobacteria,2K1BD@204457|Sphingomonadales	1224|Proteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WH3_k127_11402479_3	1248917.ANFX01000012_gene1768	9.06e-180	574.0	COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,2TVGC@28211|Alphaproteobacteria,2K05K@204457|Sphingomonadales	204457|Sphingomonadales	K	LacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WH3_k127_11402479_1	1248917.ANFX01000012_gene1769	4.778e-251	780.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2U2DZ@28211|Alphaproteobacteria,2K1P7@204457|Sphingomonadales	204457|Sphingomonadales	G	Sugar transporter	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
WH3_k127_11402479_0	383381.EH30_11835	0.0	1454.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1MXVP@1224|Proteobacteria,2TTT1@28211|Alphaproteobacteria,2K0D4@204457|Sphingomonadales	204457|Sphingomonadales	HP	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_11408467_2	1479239.JQMU01000001_gene1880	7.844e-128	418.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U8U8@28211|Alphaproteobacteria,2KCU8@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
WH3_k127_11408467_0	1248917.ANFX01000029_gene2635	0.0	1014.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,2K16I@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH3_k127_11408467_1	1479239.JQMU01000001_gene1878	4.875e-210	659.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUBW@28211|Alphaproteobacteria,2K2WB@204457|Sphingomonadales	204457|Sphingomonadales	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WH3_k127_11417704_8	383381.EH30_04670	2.069e-12	66.0	COG3658@1|root,COG3658@2|Bacteria,1RF4V@1224|Proteobacteria,2U6ZE@28211|Alphaproteobacteria,2K52I@204457|Sphingomonadales	204457|Sphingomonadales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WH3_k127_11417704_7	383381.EH30_04665	9.834e-62	218.0	COG2771@1|root,COG2771@2|Bacteria,1QU5E@1224|Proteobacteria,2TW0B@28211|Alphaproteobacteria,2K6A0@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WH3_k127_11417704_1	1479239.JQMU01000001_gene293	3.343e-253	784.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,2TSKB@28211|Alphaproteobacteria,2K02Y@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family	speF	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WH3_k127_11417704_4	1479239.JQMU01000001_gene294	2.379e-90	301.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2U6EM@28211|Alphaproteobacteria,2K6NB@204457|Sphingomonadales	204457|Sphingomonadales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WH3_k127_11417704_2	1479239.JQMU01000001_gene295	1.071e-158	518.0	2DN7U@1|root,32W0N@2|Bacteria,1QZM1@1224|Proteobacteria,2TY9S@28211|Alphaproteobacteria,2KEKK@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
WH3_k127_11417704_6	1479239.JQMU01000001_gene296	6.389e-66	232.0	2CHCA@1|root,34CA8@2|Bacteria,1P2IG@1224|Proteobacteria,2UUTS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
WH3_k127_11417704_0	1479239.JQMU01000001_gene297	6.029e-256	791.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,2TVR1@28211|Alphaproteobacteria,2K0YP@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	-	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
WH3_k127_11417704_3	1248917.ANFX01000041_gene1716	2.173e-150	484.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,2K7GT@204457|Sphingomonadales	204457|Sphingomonadales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
WH3_k127_11417704_5	1479239.JQMU01000001_gene298	2.342e-67	229.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,2TRRQ@28211|Alphaproteobacteria,2K1EZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WH3_k127_11424578_0	977880.pRALTA_0157	2.593e-186	593.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VMDU@28216|Betaproteobacteria,1K21K@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1
WH3_k127_11424578_1	485915.Dret_0882	5.642e-14	75.0	2DD8W@1|root,2ZH3F@2|Bacteria,1PBGJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11437137_2	1479239.JQMU01000001_gene718	7.102e-17	80.0	29BA9@1|root,2ZY8N@2|Bacteria,1RJEZ@1224|Proteobacteria,2U9H3@28211|Alphaproteobacteria,2K4P7@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
WH3_k127_11437137_1	1122970.AUHC01000008_gene78	1e-70	245.0	2BVJ7@1|root,32QX6@2|Bacteria,1N7C0@1224|Proteobacteria,2UGAW@28211|Alphaproteobacteria,2K789@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
WH3_k127_11437137_0	1479239.JQMU01000001_gene716	9.674e-136	433.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria,2K0F2@204457|Sphingomonadales	204457|Sphingomonadales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
WH3_k127_11437137_3	1479239.JQMU01000001_gene715	1.558e-12	68.0	COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,2JZUK@204457|Sphingomonadales	204457|Sphingomonadales	H	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase)	-	-	6.6.1.2	ko:K09883	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobT,CobT_C
WH3_k127_11438656_0	1044.EH31_05375	5.523e-126	439.0	COG1629@1|root,COG2931@1|root,COG1629@2|Bacteria,COG2931@2|Bacteria,1QTVF@1224|Proteobacteria,2TW2N@28211|Alphaproteobacteria,2KE9C@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
WH3_k127_11438656_1	1390370.O203_18160	7.776e-18	99.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RZD3@1236|Gammaproteobacteria,1YHEQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	ASH,An_peroxidase,HCBP_related,HemolysinCabind
WH3_k127_11440901_1	1248917.ANFX01000016_gene2485	5.813e-95	312.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,2TVJ1@28211|Alphaproteobacteria,2K2D2@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WH3_k127_11440901_0	1122970.AUHC01000004_gene2250	9.066e-288	894.0	COG1082@1|root,COG1082@2|Bacteria,1NNTS@1224|Proteobacteria,2U06E@28211|Alphaproteobacteria,2K1T2@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl-hydrolase 97 C-terminal, oligomerisation	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
WH3_k127_11446418_1	1248917.ANFX01000033_gene749	6.321e-117	377.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2TSDM@28211|Alphaproteobacteria,2JZVF@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
WH3_k127_11446418_0	1248917.ANFX01000033_gene751	0.0	1011.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,2K1B6@204457|Sphingomonadales	204457|Sphingomonadales	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
WH3_k127_11458094_2	1479239.JQMU01000001_gene2591	8.649e-52	186.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,2JZWI@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WH3_k127_11458094_0	1479239.JQMU01000001_gene2590	2.982e-272	848.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,2TSAR@28211|Alphaproteobacteria,2K0Y7@204457|Sphingomonadales	204457|Sphingomonadales	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4130,UDG
WH3_k127_11458094_1	1479239.JQMU01000001_gene2589	3.373e-250	775.0	COG4277@1|root,COG4277@2|Bacteria,1MVCV@1224|Proteobacteria,2TT5U@28211|Alphaproteobacteria,2K0AV@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA-binding protein with the helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11485860_4	1479239.JQMU01000001_gene1415	3.087e-58	203.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2TTFE@28211|Alphaproteobacteria,2K28Z@204457|Sphingomonadales	204457|Sphingomonadales	P	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
WH3_k127_11485860_0	1479239.JQMU01000001_gene1416	7.24e-260	818.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,2K068@204457|Sphingomonadales	204457|Sphingomonadales	G	sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WH3_k127_11485860_3	1248917.ANFX01000005_gene123	3.683e-80	275.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria,2K4NG@204457|Sphingomonadales	204457|Sphingomonadales	T	GAF domain-containing protein	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
WH3_k127_11485860_1	1479239.JQMU01000001_gene1418	3.372e-105	348.0	COG3134@1|root,COG3134@2|Bacteria,1PMM0@1224|Proteobacteria,2V07S@28211|Alphaproteobacteria,2KA1N@204457|Sphingomonadales	204457|Sphingomonadales	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11485860_2	1479239.JQMU01000001_gene1419	7.981e-90	299.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,2K0RQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WH3_k127_11561264_2	1479239.JQMU01000001_gene2036	1.529e-80	269.0	COG1233@1|root,COG1233@2|Bacteria,1MX1C@1224|Proteobacteria,2TS2R@28211|Alphaproteobacteria,2K0TG@204457|Sphingomonadales	204457|Sphingomonadales	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.27	ko:K09845	ko00906,ko01100,map00906,map01100	-	R07517,R07520,R07523,R07534	RC02080	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WH3_k127_11561264_0	1248917.ANFX01000016_gene2450	1.224e-150	487.0	COG5621@1|root,COG5621@2|Bacteria,1QPJ4@1224|Proteobacteria,2TVNN@28211|Alphaproteobacteria,2K32K@204457|Sphingomonadales	204457|Sphingomonadales	S	hydroxyneurosporene synthase	-	-	4.2.1.131	ko:K09844	ko00906,ko01100,map00906,map01100	-	R07516,R07519,R07522,R07528,R07532,R07536,R07539,R07543,R09790	RC00966	ko00000,ko00001,ko01000	-	-	-	-
WH3_k127_11561264_1	1313172.YM304_02840	4.401e-84	290.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,4CNTP@84992|Acidimicrobiia	84992|Acidimicrobiia	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
WH3_k127_1159040_0	1479239.JQMU01000001_gene2058	1.106e-173	545.0	COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2TR1U@28211|Alphaproteobacteria,2K13S@204457|Sphingomonadales	204457|Sphingomonadales	U	type IV secretion system	-	-	-	ko:K03199	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	CagE_TrbE_VirB
WH3_k127_1159040_1	1122970.AUHC01000004_gene2301	3.542e-149	475.0	COG3704@1|root,COG3704@2|Bacteria,1NIX6@1224|Proteobacteria,2UK4E@28211|Alphaproteobacteria,2KCE4@204457|Sphingomonadales	204457|Sphingomonadales	U	TrbL/VirB6 plasmid conjugal transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
WH3_k127_11662301_0	1479239.JQMU01000001_gene2044	1.615e-225	708.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type Fe3 transport system, permease component	sfuB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
WH3_k127_11662301_1	1479239.JQMU01000001_gene2045	4.733e-50	179.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2K5T1@204457|Sphingomonadales	204457|Sphingomonadales	E	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH3_k127_11683650_2	1479239.JQMU01000001_gene236	6.088e-98	321.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,2K0GV@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WH3_k127_11683650_5	1479239.JQMU01000001_gene237	8.593e-50	180.0	COG5416@1|root,COG5416@2|Bacteria,1NFVX@1224|Proteobacteria,2UHIC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
WH3_k127_11683650_0	1248917.ANFX01000027_gene1094	8.365e-133	424.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria,2K06D@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WH3_k127_11683650_4	1122970.AUHC01000001_gene748	1.761e-66	228.0	COG0346@1|root,COG0346@2|Bacteria,1N36F@1224|Proteobacteria,2UCQN@28211|Alphaproteobacteria,2K600@204457|Sphingomonadales	204457|Sphingomonadales	E	bleomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11683650_3	1479239.JQMU01000001_gene239	4.521e-84	283.0	COG3153@1|root,COG3153@2|Bacteria,1QUTM@1224|Proteobacteria,2U9Q0@28211|Alphaproteobacteria,2K4VK@204457|Sphingomonadales	204457|Sphingomonadales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WH3_k127_11683650_1	1479239.JQMU01000001_gene240	1.342e-117	379.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2U7CH@28211|Alphaproteobacteria,2K03X@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
WH3_k127_11694824_1	1248917.ANFX01000035_gene1989	1.273e-95	315.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,2K06B@204457|Sphingomonadales	204457|Sphingomonadales	P	chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WH3_k127_11694824_0	1479239.JQMU01000001_gene653	5.164e-166	527.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,2K34X@204457|Sphingomonadales	204457|Sphingomonadales	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
WH3_k127_11696560_0	1479239.JQMU01000001_gene1029	0.0	1322.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TWBJ@28211|Alphaproteobacteria,2KEEC@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,MASE1,PAS_3,PAS_4,Response_reg
WH3_k127_11749163_4	1479239.JQMU01000001_gene1105	3.127e-97	323.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U59A@28211|Alphaproteobacteria,2K0G8@204457|Sphingomonadales	204457|Sphingomonadales	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
WH3_k127_11749163_3	1248917.ANFX01000018_gene2290	3.128e-116	379.0	2ANEF@1|root,31DD2@2|Bacteria,1RHST@1224|Proteobacteria,2UA6U@28211|Alphaproteobacteria,2K4B0@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11749163_1	1122970.AUHC01000012_gene895	2.085e-155	496.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,2K03K@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WH3_k127_11749163_6	1479239.JQMU01000001_gene1108	5.041e-44	162.0	COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,2K6UW@204457|Sphingomonadales	204457|Sphingomonadales	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
WH3_k127_11749163_0	1479239.JQMU01000001_gene1109	3.009e-168	531.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,2K107@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
WH3_k127_11749163_7	1479239.JQMU01000001_gene1111	3.532e-32	128.0	COG2841@1|root,COG2841@2|Bacteria,1NGDM@1224|Proteobacteria,2VAQQ@28211|Alphaproteobacteria,2K80C@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF465)	-	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
WH3_k127_11749163_5	383381.EH30_13495	6.127e-84	284.0	28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,2U8ZT@28211|Alphaproteobacteria,2K4I9@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11749163_2	1479239.JQMU01000001_gene1112	5.343e-148	482.0	28NPB@1|root,2ZBP9@2|Bacteria,1R3HY@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
WH3_k127_11749163_8	383381.EH30_13505	2.534e-12	68.0	COG3326@1|root,COG3326@2|Bacteria,1NGR5@1224|Proteobacteria,2UJDY@28211|Alphaproteobacteria,2KBEU@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
WH3_k127_11758_2	1479239.JQMU01000001_gene2697	1.194e-101	331.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,2K2GE@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WH3_k127_11758_0	1479239.JQMU01000001_gene2696	7.232e-184	581.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,2TTCR@28211|Alphaproteobacteria,2K84S@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
WH3_k127_11758_1	1122970.AUHC01000001_gene476	1.102e-132	435.0	COG2367@1|root,COG2367@2|Bacteria,1RAH0@1224|Proteobacteria,2U6HN@28211|Alphaproteobacteria,2K024@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
WH3_k127_11824333_3	237727.NAP1_14223	3.462e-79	273.0	COG0352@1|root,COG0352@2|Bacteria,1RKGX@1224|Proteobacteria,2UB4W@28211|Alphaproteobacteria,2K57F@204457|Sphingomonadales	204457|Sphingomonadales	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
WH3_k127_11824333_2	1479239.JQMU01000001_gene1151	1.19e-116	377.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,2K0C6@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WH3_k127_11824333_0	1479239.JQMU01000001_gene1149	0.0	1317.0	COG4773@1|root,COG4773@2|Bacteria,1R3UW@1224|Proteobacteria,2U2CD@28211|Alphaproteobacteria,2KEDM@204457|Sphingomonadales	204457|Sphingomonadales	M	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_11824333_1	1248917.ANFX01000013_gene1428	3.282e-138	441.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,2K0BN@204457|Sphingomonadales	204457|Sphingomonadales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
WH3_k127_11904897_0	1479239.JQMU01000001_gene1723	0.0	1663.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales	204457|Sphingomonadales	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WH3_k127_11904897_1	1479239.JQMU01000001_gene1722	5.094e-65	224.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,2U7VQ@28211|Alphaproteobacteria,2K0H4@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
WH3_k127_1190713_1	1123269.NX02_26720	6.806e-111	362.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TTEV@28211|Alphaproteobacteria,2K2QZ@204457|Sphingomonadales	204457|Sphingomonadales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
WH3_k127_1190713_0	1030157.AFMP01000013_gene3343	6.759e-133	434.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2K1VP@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
WH3_k127_11911406_4	291985.CCSI01000004_gene609	8.849e-48	179.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,2TSVP@28211|Alphaproteobacteria,2K028@204457|Sphingomonadales	204457|Sphingomonadales	G	Transporter	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
WH3_k127_11911406_1	1248917.ANFX01000012_gene1778	9.667e-192	605.0	COG1609@1|root,COG1609@2|Bacteria,1R4IR@1224|Proteobacteria,2U4DM@28211|Alphaproteobacteria,2KCZ3@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
WH3_k127_11911406_0	1248917.ANFX01000012_gene1779	0.0	1571.0	COG2352@1|root,COG2352@2|Bacteria,1Q2KN@1224|Proteobacteria,2VC03@28211|Alphaproteobacteria,2K11R@204457|Sphingomonadales	204457|Sphingomonadales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
WH3_k127_11911406_2	1248917.ANFX01000012_gene1780	5.806e-185	582.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2U0CA@28211|Alphaproteobacteria,2K0NK@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
WH3_k127_11911406_3	1479239.JQMU01000001_gene2193	6.134e-169	533.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,2U2MN@28211|Alphaproteobacteria,2K2I5@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
WH3_k127_11925441_4	1479239.JQMU01000001_gene2625	6.255e-55	192.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2TS0D@28211|Alphaproteobacteria,2K0G0@204457|Sphingomonadales	204457|Sphingomonadales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WH3_k127_11925441_1	1479239.JQMU01000001_gene2626	1.053e-178	562.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,2K0Z9@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_11925441_2	1479239.JQMU01000001_gene2627	3.237e-145	463.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,2JZWT@204457|Sphingomonadales	204457|Sphingomonadales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WH3_k127_11925441_3	1479239.JQMU01000001_gene2628	6.149e-83	279.0	2F3B5@1|root,2ZGM3@2|Bacteria,1QWIX@1224|Proteobacteria,2TWYP@28211|Alphaproteobacteria,2KEGD@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
WH3_k127_11925441_0	1479239.JQMU01000001_gene2629	6.965e-229	715.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,2K0II@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WH3_k127_11936227_0	1248917.ANFX01000051_gene443	0.0	1225.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,2K1X7@204457|Sphingomonadales	204457|Sphingomonadales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
WH3_k127_11936227_1	1479239.JQMU01000001_gene2099	2.992e-76	257.0	COG2050@1|root,COG2050@2|Bacteria,1RBET@1224|Proteobacteria,2U5TM@28211|Alphaproteobacteria,2K8CX@204457|Sphingomonadales	204457|Sphingomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH3_k127_11936227_2	1248917.ANFX01000051_gene440	2.269e-18	84.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2UCJF@28211|Alphaproteobacteria,2K4FV@204457|Sphingomonadales	204457|Sphingomonadales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WH3_k127_11955948_3	1248917.ANFX01000045_gene1284	9.855e-140	444.0	COG1028@1|root,COG1028@2|Bacteria,1R942@1224|Proteobacteria,2U1U1@28211|Alphaproteobacteria,2K0XC@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_11955948_1	1479239.JQMU01000001_gene881	1.062e-222	691.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTYY@28211|Alphaproteobacteria,2JZXZ@204457|Sphingomonadales	204457|Sphingomonadales	S	alcohol dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
WH3_k127_11955948_2	1248917.ANFX01000045_gene1282	3.152e-141	455.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1NEK8@1224|Proteobacteria,2U4EQ@28211|Alphaproteobacteria,2K10J@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
WH3_k127_11955948_0	1479239.JQMU01000001_gene883	0.0	1174.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2U2ZG@28211|Alphaproteobacteria,2K2FX@204457|Sphingomonadales	204457|Sphingomonadales	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
WH3_k127_11962780_6	1248917.ANFX01000051_gene454	2.836e-21	93.0	2B2V7@1|root,31VFS@2|Bacteria,1NBPZ@1224|Proteobacteria,2UGTR@28211|Alphaproteobacteria,2KCC5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11962780_1	1479239.JQMU01000001_gene2086	3.698e-61	213.0	28X1J@1|root,30MES@2|Bacteria,1MZB2@1224|Proteobacteria,2UCMI@28211|Alphaproteobacteria,2KDNT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11962780_3	1248917.ANFX01000051_gene457	4.721e-26	118.0	2ABNP@1|root,3114I@2|Bacteria,1PP7J@1224|Proteobacteria,2V1QS@28211|Alphaproteobacteria,2KBWJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11962780_2	1122970.AUHC01000004_gene2347	2.201e-31	128.0	2APSZ@1|root,31EX3@2|Bacteria,1P6QC@1224|Proteobacteria,2UYJB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11962780_4	1479239.JQMU01000001_gene2084	6.623e-26	115.0	29B0T@1|root,2ZXZQ@2|Bacteria,1ND25@1224|Proteobacteria,2UJ2J@28211|Alphaproteobacteria,2K6SU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11962780_5	1122970.AUHC01000004_gene2345	1.575e-23	102.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria,2UGT0@28211|Alphaproteobacteria,2K7V2@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11962780_0	1248917.ANFX01000051_gene461	7.458e-70	238.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,2K4H9@204457|Sphingomonadales	204457|Sphingomonadales	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
WH3_k127_11968474_2	1479239.JQMU01000001_gene1272	2.256e-121	401.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,2K1H1@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WH3_k127_11968474_1	1248917.ANFX01000013_gene1589	6.131e-165	529.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2TRT6@28211|Alphaproteobacteria,2K1NI@204457|Sphingomonadales	204457|Sphingomonadales	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH3_k127_11968474_0	1479239.JQMU01000001_gene1270	8.46e-292	904.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,2TTVY@28211|Alphaproteobacteria,2K0BQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Flotillin	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Flot
WH3_k127_11968474_4	1479239.JQMU01000001_gene1269	3.927e-104	342.0	COG1585@1|root,COG1585@2|Bacteria,1RG29@1224|Proteobacteria,2U37H@28211|Alphaproteobacteria,2K4TH@204457|Sphingomonadales	204457|Sphingomonadales	OU	Protein of unknown function (DUF1449)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1449
WH3_k127_11968474_3	1479239.JQMU01000001_gene1268	1.437e-112	364.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TU15@28211|Alphaproteobacteria,2K1GE@204457|Sphingomonadales	204457|Sphingomonadales	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_11974040_2	1122970.AUHC01000011_gene2698	2.789e-141	454.0	COG1028@1|root,COG1028@2|Bacteria,1NB6S@1224|Proteobacteria,2U1XH@28211|Alphaproteobacteria,2K20C@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_11974040_4	1479239.JQMU01000001_gene1575	4.717e-77	263.0	COG3631@1|root,COG3631@2|Bacteria,1RH7J@1224|Proteobacteria,2UB56@28211|Alphaproteobacteria,2K5TZ@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
WH3_k127_11974040_5	565045.NOR51B_1378	6.829e-20	94.0	COG1359@1|root,COG1359@2|Bacteria,1N7AV@1224|Proteobacteria	1224|Proteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WH3_k127_11974040_3	1248917.ANFX01000019_gene2332	3.521e-88	296.0	COG0746@1|root,COG0746@2|Bacteria,1N1GK@1224|Proteobacteria,2UDGM@28211|Alphaproteobacteria,2K5W9@204457|Sphingomonadales	204457|Sphingomonadales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WH3_k127_11974040_1	1248917.ANFX01000019_gene2331	7.109e-207	649.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2K0D7@204457|Sphingomonadales	204457|Sphingomonadales	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
WH3_k127_11974040_0	1479239.JQMU01000001_gene1571	2.083e-289	891.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,2K20E@204457|Sphingomonadales	204457|Sphingomonadales	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WH3_k127_11975682_7	237727.NAP1_14473	2.37e-10	66.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_2,TonB_C
WH3_k127_11975682_3	1248917.ANFX01000037_gene2186	1.384e-121	394.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,2K47C@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WH3_k127_11975682_2	1479239.JQMU01000001_gene452	3.33e-227	709.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2TW1S@28211|Alphaproteobacteria,2K09D@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_11975682_5	1479239.JQMU01000001_gene453	4.63e-23	100.0	2BSNS@1|root,32MRD@2|Bacteria,1PA9T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_11975682_0	1248917.ANFX01000037_gene2182	3.335e-321	988.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2K0EY@204457|Sphingomonadales	204457|Sphingomonadales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WH3_k127_11975682_4	1479239.JQMU01000001_gene456	1.089e-73	253.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria,2K5EU@204457|Sphingomonadales	204457|Sphingomonadales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
WH3_k127_11975682_1	1479239.JQMU01000001_gene457	2.311e-241	753.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2U05U@28211|Alphaproteobacteria,2K1IQ@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WH3_k127_11979942_0	1479239.JQMU01000001_gene1118	1.263e-316	972.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2K0F8@204457|Sphingomonadales	204457|Sphingomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
WH3_k127_12013491_9	1479239.JQMU01000001_gene751	7.292e-140	445.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,2K07H@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WH3_k127_12013491_12	1122612.AUBA01000020_gene2566	1.459e-105	355.0	COG0299@1|root,COG3801@1|root,COG0299@2|Bacteria,COG3801@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,2K28Q@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N,YjbR
WH3_k127_12013491_6	1479239.JQMU01000001_gene753	2.346e-204	642.0	2BWJ3@1|root,2Z8E8@2|Bacteria,1NUPJ@1224|Proteobacteria,2URT0@28211|Alphaproteobacteria,2K4KK@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
WH3_k127_12013491_15	666685.R2APBS1_2528	7.23e-74	257.0	2A1SN@1|root,30Q1C@2|Bacteria,1NXN6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12013491_14	1248917.ANFX01000032_gene935	2.542e-81	273.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,2K3WY@204457|Sphingomonadales	204457|Sphingomonadales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WH3_k127_12013491_11	1248917.ANFX01000032_gene936	8.175e-112	364.0	COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,2TU2C@28211|Alphaproteobacteria,2K1H9@204457|Sphingomonadales	204457|Sphingomonadales	Q	Dioxygenase	pcaH	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C,PCDO_beta_N
WH3_k127_12013491_16	1479239.JQMU01000001_gene755	2.048e-68	238.0	2AFKQ@1|root,315MQ@2|Bacteria,1NE3C@1224|Proteobacteria,2UICA@28211|Alphaproteobacteria,2K6ZJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12013491_17	1479239.JQMU01000001_gene756	3.745e-68	236.0	COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,2K5Y0@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
WH3_k127_12013491_20	279238.Saro_0891	4.965e-24	101.0	COG4338@1|root,COG4338@2|Bacteria,1NGIS@1224|Proteobacteria,2UJAQ@28211|Alphaproteobacteria,2K7RD@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2256
WH3_k127_12013491_2	1479239.JQMU01000001_gene757	1.021e-276	861.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,2K04B@204457|Sphingomonadales	204457|Sphingomonadales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WH3_k127_12013491_0	1479239.JQMU01000001_gene758	0.0	1308.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,2K1GQ@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
WH3_k127_12013491_4	1479239.JQMU01000001_gene759	1.051e-224	703.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2TSJ3@28211|Alphaproteobacteria,2K0UR@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N,SurA_N_3
WH3_k127_12013491_7	1479239.JQMU01000001_gene760	3.46e-177	561.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2K0HZ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
WH3_k127_12013491_8	1479239.JQMU01000001_gene761	3.778e-146	466.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,2K042@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WH3_k127_12013491_1	1479239.JQMU01000001_gene683	0.0	1261.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria,2K0KC@204457|Sphingomonadales	204457|Sphingomonadales	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
WH3_k127_12013491_5	1479239.JQMU01000001_gene682	1.167e-217	679.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TRTW@28211|Alphaproteobacteria,2K0AC@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WH3_k127_12013491_10	46429.BV95_02224	3.601e-133	434.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,2TREF@28211|Alphaproteobacteria,2K0MB@204457|Sphingomonadales	204457|Sphingomonadales	E	arginine N-succinyltransferase	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
WH3_k127_12013491_3	1479239.JQMU01000001_gene680	6.54e-250	773.0	COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,2U0HD@28211|Alphaproteobacteria,2K01P@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	astB	-	3.5.3.23	ko:K01484	ko00330,ko01100,map00330,map01100	-	R04189	RC00024	ko00000,ko00001,ko01000	-	-	-	AstB
WH3_k127_12013491_19	1122970.AUHC01000008_gene40	3.518e-33	130.0	2A2WM@1|root,30RAQ@2|Bacteria,1NC0Y@1224|Proteobacteria,2UGYZ@28211|Alphaproteobacteria,2K6WP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12013491_22	491916.RHECIAT_CH0002943	2.5e-05	48.0	2A9UM@1|root,30Z2G@2|Bacteria,1PQIA@1224|Proteobacteria,2V2X8@28211|Alphaproteobacteria,4BJT2@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12013491_18	1122970.AUHC01000008_gene39	3.314e-65	225.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,2K54X@204457|Sphingomonadales	204457|Sphingomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WH3_k127_12013491_13	1122970.AUHC01000008_gene38	2.989e-104	344.0	COG1704@1|root,COG1704@2|Bacteria,1RCHG@1224|Proteobacteria,2U6AZ@28211|Alphaproteobacteria,2KDEX@204457|Sphingomonadales	204457|Sphingomonadales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WH3_k127_12013491_21	1479239.JQMU01000001_gene764	3.222e-06	49.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,2K1AR@204457|Sphingomonadales	204457|Sphingomonadales	S	Methanol dehydrogenase	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
WH3_k127_12051127_0	1479239.JQMU01000001_gene1148	0.0	1309.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,2K0BN@204457|Sphingomonadales	204457|Sphingomonadales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
WH3_k127_12051127_1	1479239.JQMU01000001_gene1147	5.577e-100	328.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JZZB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_12111281_0	1248917.ANFX01000032_gene965	0.0	1449.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TW2G@28211|Alphaproteobacteria,2KE9A@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_12111281_1	1479239.JQMU01000001_gene776	0.0	1152.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,2K169@204457|Sphingomonadales	204457|Sphingomonadales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WH3_k127_12111281_3	1248917.ANFX01000032_gene968	9.806e-251	781.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VF3C@28211|Alphaproteobacteria,2KDVP@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WH3_k127_12111281_12	1479239.JQMU01000001_gene780	2.087e-68	233.0	COG0346@1|root,COG0346@2|Bacteria,1RIFB@1224|Proteobacteria,2VFXA@28211|Alphaproteobacteria,2KE0A@204457|Sphingomonadales	204457|Sphingomonadales	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH3_k127_12111281_10	1479239.JQMU01000001_gene781	9.465e-119	386.0	COG3921@1|root,COG3921@2|Bacteria,1PZMM@1224|Proteobacteria,2TR6H@28211|Alphaproteobacteria,2KD3Z@204457|Sphingomonadales	204457|Sphingomonadales	S	Extensin-like protein C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
WH3_k127_12111281_9	1479239.JQMU01000001_gene782	3.402e-121	390.0	COG4566@1|root,COG4566@2|Bacteria,1NW8P@1224|Proteobacteria,2URZE@28211|Alphaproteobacteria,2K4R6@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WH3_k127_12111281_7	1479239.JQMU01000001_gene783	1.325e-141	452.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2U09K@28211|Alphaproteobacteria,2K318@204457|Sphingomonadales	204457|Sphingomonadales	O	proteasome-type protease	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
WH3_k127_12111281_6	1479239.JQMU01000001_gene784	6.099e-154	492.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2TTZY@28211|Alphaproteobacteria,2K2SK@204457|Sphingomonadales	204457|Sphingomonadales	E	COG1305 Transglutaminase-like enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
WH3_k127_12111281_5	1479239.JQMU01000001_gene785	4.48e-185	580.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2TQUM@28211|Alphaproteobacteria,2K13E@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
WH3_k127_12111281_2	1248917.ANFX01000032_gene975	2.325e-297	914.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2TRI7@28211|Alphaproteobacteria,2K23M@204457|Sphingomonadales	204457|Sphingomonadales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
WH3_k127_12111281_8	1248917.ANFX01000032_gene976	4.361e-141	452.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2TSQC@28211|Alphaproteobacteria,2K4XJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
WH3_k127_12111281_11	1479239.JQMU01000001_gene788	7.344e-69	244.0	2EHBD@1|root,33B38@2|Bacteria,1MZRE@1224|Proteobacteria,2UE9D@28211|Alphaproteobacteria,2K709@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
WH3_k127_12111281_4	1248917.ANFX01000032_gene978	2.175e-219	702.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,2K0F9@204457|Sphingomonadales	204457|Sphingomonadales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WH3_k127_12112922_6	1479239.JQMU01000001_gene171	1.937e-08	55.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria,2K043@204457|Sphingomonadales	204457|Sphingomonadales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
WH3_k127_12112922_3	237727.NAP1_09782	6.862e-110	384.0	COG0790@1|root,COG5640@1|root,COG0790@2|Bacteria,COG5640@2|Bacteria,1PEP7@1224|Proteobacteria,2VE7G@28211|Alphaproteobacteria,2K9SA@204457|Sphingomonadales	204457|Sphingomonadales	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
WH3_k127_12112922_2	291985.CCSI01000004_gene770	2.319e-125	413.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2V1FI@28211|Alphaproteobacteria,2KBH4@204457|Sphingomonadales	204457|Sphingomonadales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WH3_k127_12112922_0	1479239.JQMU01000001_gene1329	8.175e-198	623.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2U36M@28211|Alphaproteobacteria,2K2U1@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin superfamily protein	-	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
WH3_k127_12112922_5	1479239.JQMU01000001_gene1330	7.929e-33	131.0	2EHCE@1|root,33B49@2|Bacteria,1NIBN@1224|Proteobacteria,2V6KJ@28211|Alphaproteobacteria,2K6FS@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12112922_1	1479239.JQMU01000001_gene173	2.438e-154	490.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,2JZVK@204457|Sphingomonadales	204457|Sphingomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
WH3_k127_12112922_4	1479239.JQMU01000001_gene174	4.645e-92	308.0	2DNPG@1|root,32YEX@2|Bacteria,1NNRG@1224|Proteobacteria,2UKH6@28211|Alphaproteobacteria,2K45J@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12154712_0	1479239.JQMU01000001_gene1746	1.265e-154	490.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,2K12I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH3_k127_12154712_1	1479239.JQMU01000001_gene1747	1.42e-99	326.0	COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria,2K1F0@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the 3-hydroxyisobutyrate dehydrogenase family	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WH3_k127_12171637_0	1479239.JQMU01000001_gene929	1.313e-249	771.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,2K0U9@204457|Sphingomonadales	204457|Sphingomonadales	I	poly(R)-hydroxyalkanoic acid synthase	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
WH3_k127_12171637_1	1479239.JQMU01000001_gene930	1.648e-103	342.0	COG5490@1|root,COG5490@2|Bacteria,1N3RI@1224|Proteobacteria,2UDTZ@28211|Alphaproteobacteria,2K476@204457|Sphingomonadales	204457|Sphingomonadales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
WH3_k127_12171637_2	1122970.AUHC01000013_gene1040	9.996e-61	211.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,2K5BT@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
WH3_k127_12171637_3	1479239.JQMU01000001_gene932	2.354e-11	65.0	COG2343@1|root,COG2343@2|Bacteria,1RJ3M@1224|Proteobacteria,2U98N@28211|Alphaproteobacteria,2K4EZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
WH3_k127_12188063_0	1479239.JQMU01000001_gene533	8.797e-310	954.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,2K0PK@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
WH3_k127_12188063_2	1479239.JQMU01000001_gene534	8.455e-76	258.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2U75V@28211|Alphaproteobacteria,2K3X2@204457|Sphingomonadales	204457|Sphingomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WH3_k127_12188063_4	1248917.ANFX01000011_gene188	2.531e-60	212.0	COG5342@1|root,COG5342@2|Bacteria,1NVB8@1224|Proteobacteria,2UAQU@28211|Alphaproteobacteria,2K5ZJ@204457|Sphingomonadales	204457|Sphingomonadales	S	invasion associated locus B	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12188063_1	1248917.ANFX01000011_gene187	2.537e-256	795.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2TQT3@28211|Alphaproteobacteria,2K0CT@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
WH3_k127_12188063_3	1248917.ANFX01000011_gene186	6.315e-73	250.0	2C3YK@1|root,2ZHJ2@2|Bacteria,1RKGM@1224|Proteobacteria,2UBK5@28211|Alphaproteobacteria,2K5GJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12233077_0	1479239.JQMU01000001_gene476	0.0	1449.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,2K0GI@204457|Sphingomonadales	204457|Sphingomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WH3_k127_12233077_1	1479239.JQMU01000001_gene475	3.588e-110	360.0	COG2825@1|root,COG2825@2|Bacteria,1NFPH@1224|Proteobacteria,2U9NJ@28211|Alphaproteobacteria,2KDJR@204457|Sphingomonadales	204457|Sphingomonadales	M	Outer membrane protein (OmpH-like)	-	-	-	-	-	-	-	-	-	-	-	-	OmpH
WH3_k127_12233077_2	1479239.JQMU01000001_gene474	1.249e-89	296.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria,2K4JA@204457|Sphingomonadales	204457|Sphingomonadales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
WH3_k127_12233077_3	1479239.JQMU01000001_gene473	7.662e-41	154.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria,2K643@204457|Sphingomonadales	204457|Sphingomonadales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WH3_k127_12233077_4	1479239.JQMU01000001_gene472	1.393e-13	70.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,2UCF1@28211|Alphaproteobacteria,2K7EE@204457|Sphingomonadales	204457|Sphingomonadales	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
WH3_k127_12246903_1	1479239.JQMU01000001_gene1158	2.376e-11	66.0	COG2199@1|root,COG3706@2|Bacteria,1MW39@1224|Proteobacteria,2U25F@28211|Alphaproteobacteria,2KDVH@204457|Sphingomonadales	204457|Sphingomonadales	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
WH3_k127_12246903_0	1479239.JQMU01000001_gene1157	6.211e-193	606.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,2K0M7@204457|Sphingomonadales	204457|Sphingomonadales	P	Phosphate ABC transporter substrate-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WH3_k127_12289780_2	1479239.JQMU01000001_gene188	2.967e-40	154.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U0U5@28211|Alphaproteobacteria,2K08M@204457|Sphingomonadales	204457|Sphingomonadales	V	proteins, homologs of microcin C7 resistance protein MccF	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
WH3_k127_12289780_1	1248917.ANFX01000030_gene504	3.617e-250	778.0	COG0773@1|root,COG0773@2|Bacteria,1MVCG@1224|Proteobacteria,2TTDN@28211|Alphaproteobacteria,2K0S4@204457|Sphingomonadales	204457|Sphingomonadales	M	UDP-N-acetylmuramate-alanine ligase	-	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH3_k127_12289780_0	1248917.ANFX01000030_gene502	2.12e-304	936.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K9C8@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_12289780_3	1122970.AUHC01000001_gene701	3.804e-24	102.0	COG0625@1|root,COG0625@2|Bacteria,1PA0Q@1224|Proteobacteria,2TVIC@28211|Alphaproteobacteria,2K4XA@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
WH3_k127_12308788_8	1479239.JQMU01000001_gene729	4.642e-86	285.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2K11U@204457|Sphingomonadales	204457|Sphingomonadales	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
WH3_k127_12308788_2	1479239.JQMU01000001_gene730	3.49e-247	767.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2K0PV@204457|Sphingomonadales	204457|Sphingomonadales	C	dehydratase	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
WH3_k127_12308788_7	1479239.JQMU01000001_gene731	1.844e-112	366.0	COG1335@1|root,COG1335@2|Bacteria,1NZJ1@1224|Proteobacteria,2VG5P@28211|Alphaproteobacteria,2K4F2@204457|Sphingomonadales	204457|Sphingomonadales	Q	Isochorismatase family	-	-	3.5.1.107	ko:K13995	ko00760,ko01120,map00760,map01120	M00622	R03540	RC00950	ko00000,ko00001,ko00002,ko01000	-	-	-	Isochorismatase
WH3_k127_12308788_5	1122970.AUHC01000004_gene2307	2.449e-165	523.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2TTZV@28211|Alphaproteobacteria,2K1FS@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
WH3_k127_12308788_1	1479239.JQMU01000001_gene2064	1.344e-264	822.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TR1W@28211|Alphaproteobacteria,2JZYK@204457|Sphingomonadales	204457|Sphingomonadales	FP	exopolyphosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
WH3_k127_12308788_0	1479239.JQMU01000001_gene2063	0.0	1311.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,2K167@204457|Sphingomonadales	204457|Sphingomonadales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WH3_k127_12308788_3	1479239.JQMU01000001_gene2062	6.725e-196	616.0	COG0630@1|root,COG0630@2|Bacteria,1QUJ6@1224|Proteobacteria,2TW2D@28211|Alphaproteobacteria,2K02G@204457|Sphingomonadales	204457|Sphingomonadales	NU	IV secretion system protein	-	-	-	ko:K03196	ko03070,ko05120,map03070,map05120	M00333,M00564	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T2SSE
WH3_k127_12308788_4	1479239.JQMU01000001_gene2061	9.817e-171	546.0	COG2948@1|root,COG2948@2|Bacteria,1MU7U@1224|Proteobacteria,2VEQH@28211|Alphaproteobacteria,2KDT6@204457|Sphingomonadales	204457|Sphingomonadales	U	Bacterial conjugation TrbI-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TrbI
WH3_k127_12308788_6	1479239.JQMU01000001_gene2060	8.713e-122	393.0	COG3504@1|root,COG3504@2|Bacteria,1RASB@1224|Proteobacteria,2U5SW@28211|Alphaproteobacteria,2K4BJ@204457|Sphingomonadales	204457|Sphingomonadales	U	Conjugal transfer protein	-	-	-	ko:K03204	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	CagX
WH3_k127_12314762_1	1479239.JQMU01000001_gene1956	1.833e-77	264.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria,2K57J@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WH3_k127_12314762_0	1479239.JQMU01000001_gene1957	2.392e-155	495.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,2JZZ1@204457|Sphingomonadales	204457|Sphingomonadales	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
WH3_k127_12314762_2	1479239.JQMU01000001_gene1958	2.257e-24	102.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,2K0ZN@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
WH3_k127_12400860_8	1248917.ANFX01000051_gene462	6.267e-32	124.0	COG3000@1|root,COG3000@2|Bacteria,1RJ68@1224|Proteobacteria,2U9CS@28211|Alphaproteobacteria,2K3D1@204457|Sphingomonadales	204457|Sphingomonadales	I	hydroxylase	-	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
WH3_k127_12400860_6	1545915.JROG01000009_gene2858	1.418e-36	142.0	COG0346@1|root,COG0346@2|Bacteria,1NA4J@1224|Proteobacteria,2UG20@28211|Alphaproteobacteria,2K7BD@204457|Sphingomonadales	204457|Sphingomonadales	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH3_k127_12400860_7	517722.AEUE01000007_gene298	2.089e-33	138.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,2K0AA@204457|Sphingomonadales	28211|Alphaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WH3_k127_12400860_1	1248760.ANFZ01000014_gene2190	1.322e-220	694.0	COG3746@1|root,COG3746@2|Bacteria,1R45W@1224|Proteobacteria,2U0GV@28211|Alphaproteobacteria,2K0VN@204457|Sphingomonadales	204457|Sphingomonadales	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
WH3_k127_12400860_4	1122970.AUHC01000009_gene316	2.123e-57	201.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2K62B@204457|Sphingomonadales	204457|Sphingomonadales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
WH3_k127_12400860_0	1479239.JQMU01000001_gene516	5.358e-301	927.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,2K1DA@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WH3_k127_12400860_3	1479239.JQMU01000001_gene515	2.735e-176	557.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,2K18K@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WH3_k127_12400860_2	1479239.JQMU01000001_gene514	7.712e-211	660.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,2TTA7@28211|Alphaproteobacteria,2K1XD@204457|Sphingomonadales	204457|Sphingomonadales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WH3_k127_12400860_5	1479239.JQMU01000001_gene513	8.171e-38	142.0	COG1396@1|root,COG1396@2|Bacteria,1RKW7@1224|Proteobacteria,2U9PU@28211|Alphaproteobacteria,2K2H6@204457|Sphingomonadales	204457|Sphingomonadales	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
WH3_k127_12405029_1	1122970.AUHC01000009_gene197	3.532e-23	109.0	COG2173@1|root,COG2173@2|Bacteria,1RENK@1224|Proteobacteria,2TRK8@28211|Alphaproteobacteria,2KC61@204457|Sphingomonadales	204457|Sphingomonadales	E	D-ala-D-ala dipeptidase	ddpX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15
WH3_k127_12405029_0	383381.EH30_08095	7.395e-261	822.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2JZXS@204457|Sphingomonadales	204457|Sphingomonadales	E	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WH3_k127_12414413_2	1248917.ANFX01000032_gene845	1.721e-33	132.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria,2K0WW@204457|Sphingomonadales	204457|Sphingomonadales	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
WH3_k127_12414413_0	1479239.JQMU01000001_gene666	2.787e-237	739.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,2K0TI@204457|Sphingomonadales	204457|Sphingomonadales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
WH3_k127_12414413_1	1248917.ANFX01000032_gene847	3.753e-129	412.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria,2K0JX@204457|Sphingomonadales	204457|Sphingomonadales	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
WH3_k127_12433813_1	1122970.AUHC01000002_gene1462	1.788e-79	265.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2K17H@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WH3_k127_12433813_0	1479239.JQMU01000001_gene867	1.499e-113	368.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,2K0TW@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WH3_k127_12433813_2	1479239.JQMU01000001_gene868	5.929e-39	146.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2TTI0@28211|Alphaproteobacteria,2K2BH@204457|Sphingomonadales	204457|Sphingomonadales	I	Phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WH3_k127_12437673_0	1479239.JQMU01000001_gene2612	1.695e-299	922.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2K0GG@204457|Sphingomonadales	204457|Sphingomonadales	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WH3_k127_12437673_1	1479239.JQMU01000001_gene2613	2.77e-162	515.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,2K0WU@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WH3_k127_12472067_1	287.DR97_1301	4.465e-125	401.0	28IYA@1|root,2Z8W2@2|Bacteria,1MW8D@1224|Proteobacteria,1RQ0E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3275
WH3_k127_12472067_2	1005395.CSV86_16355	1.492e-85	284.0	28P2G@1|root,2ZBYJ@2|Bacteria,1RAD3@1224|Proteobacteria,1TC44@1236|Gammaproteobacteria,1YZ69@136845|Pseudomonas putida group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12472067_0	596154.Alide2_1756	2.188e-139	444.0	28HAI@1|root,2Z7MW@2|Bacteria,1MX1B@1224|Proteobacteria,2VJMR@28216|Betaproteobacteria,4ACUU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12472067_3	1234364.AMSF01000058_gene867	3.141e-22	105.0	COG0827@1|root,COG0827@2|Bacteria,1MWPP@1224|Proteobacteria,1RR5X@1236|Gammaproteobacteria,1X3AA@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12488004_1	1479239.JQMU01000001_gene1121	2.484e-53	196.0	2FB68@1|root,31BVD@2|Bacteria,1NZZ3@1224|Proteobacteria,2UUF9@28211|Alphaproteobacteria,2KDNH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12488004_2	1479239.JQMU01000001_gene1120	8.34e-44	162.0	COG4391@1|root,COG4391@2|Bacteria,1N7F4@1224|Proteobacteria,2UHY4@28211|Alphaproteobacteria,2K6U4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
WH3_k127_12488004_0	1479239.JQMU01000001_gene1119	5.533e-138	447.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,2K06G@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_12488886_1	1248917.ANFX01000013_gene1585	9.599e-135	436.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2TQJU@28211|Alphaproteobacteria,2K2JV@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
WH3_k127_12488886_2	1248917.ANFX01000013_gene1584	1.9e-90	302.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,2K4IB@204457|Sphingomonadales	204457|Sphingomonadales	O	Alkyl hydroperoxide reductase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WH3_k127_12488886_0	1479239.JQMU01000001_gene1263	0.0	1180.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,2K1YP@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
WH3_k127_12490815_1	1479239.JQMU01000001_gene1323	1.735e-71	243.0	COG2207@1|root,COG2207@2|Bacteria,1RAXU@1224|Proteobacteria,2U682@28211|Alphaproteobacteria,2K33E@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WH3_k127_12490815_0	1479239.JQMU01000001_gene1325	2.589e-159	507.0	COG2207@1|root,COG2207@2|Bacteria,1RAXU@1224|Proteobacteria,2UQNW@28211|Alphaproteobacteria,2K8RN@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WH3_k127_12490815_2	1248917.ANFX01000021_gene1648	9.284e-64	219.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,2K4FX@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WH3_k127_12490815_3	1248917.ANFX01000021_gene1649	1.838e-36	139.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,2K5YR@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WH3_k127_12502858_2	1479239.JQMU01000001_gene2617	4.877e-12	66.0	COG5031@1|root,COG5031@2|Bacteria,1RE8M@1224|Proteobacteria,2U8V6@28211|Alphaproteobacteria,2K47N@204457|Sphingomonadales	204457|Sphingomonadales	H	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	-	-	-	-	-	-	-	-	-	-	-	-	Coq4
WH3_k127_12502858_1	1479239.JQMU01000001_gene2616	1.183e-119	390.0	COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,2TTZC@28211|Alphaproteobacteria,2K31F@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WH3_k127_12502858_0	1248917.ANFX01000008_gene369	9.363e-152	483.0	COG5031@1|root,COG5031@2|Bacteria,1RGXT@1224|Proteobacteria,2U8F1@28211|Alphaproteobacteria,2K2NK@204457|Sphingomonadales	204457|Sphingomonadales	H	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	-	-	-	ko:K18586	-	-	-	-	ko00000	-	-	-	Coq4
WH3_k127_12502858_3	1479239.JQMU01000001_gene2614	7e-12	65.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2TSEU@28211|Alphaproteobacteria,2K069@204457|Sphingomonadales	204457|Sphingomonadales	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
WH3_k127_1250769_2	1479239.JQMU01000001_gene1339	6.412e-68	233.0	2C068@1|root,30N9J@2|Bacteria,1RG08@1224|Proteobacteria,2U9FG@28211|Alphaproteobacteria,2K56D@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3035)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3035
WH3_k127_1250769_1	1479239.JQMU01000001_gene1338	2.893e-87	291.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria,2K4K3@204457|Sphingomonadales	204457|Sphingomonadales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WH3_k127_1250769_0	1479239.JQMU01000001_gene1337	1.62e-233	724.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,2K0GR@204457|Sphingomonadales	204457|Sphingomonadales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WH3_k127_12531071_0	1479239.JQMU01000001_gene1353	3.4e-231	719.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,2K1HV@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WH3_k127_12531071_3	1479239.JQMU01000001_gene1352	5.746e-51	184.0	2A6GH@1|root,30V9N@2|Bacteria,1PPCB@1224|Proteobacteria,2V1UX@28211|Alphaproteobacteria,2KC2F@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12531071_2	1479239.JQMU01000001_gene1351	2.784e-56	198.0	2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria,2K54G@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1153
WH3_k127_12531071_4	1479239.JQMU01000001_gene1350	2.331e-38	145.0	COG2261@1|root,COG2261@2|Bacteria,1N3E3@1224|Proteobacteria,2UEBF@28211|Alphaproteobacteria,2K6UA@204457|Sphingomonadales	204457|Sphingomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WH3_k127_12531071_1	1479239.JQMU01000001_gene1349	6.736e-206	646.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2UBNR@28211|Alphaproteobacteria,2KCZE@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WH3_k127_12531071_5	1248917.ANFX01000026_gene1046	3.214e-06	49.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K0BI@204457|Sphingomonadales	204457|Sphingomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WH3_k127_12554023_2	1479239.JQMU01000001_gene1541	2.243e-154	488.0	COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,2K06A@204457|Sphingomonadales	204457|Sphingomonadales	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MipZ
WH3_k127_12554023_3	1248917.ANFX01000019_gene2380	6.963e-42	156.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNAJ_related,DnaJ
WH3_k127_12554023_1	1248917.ANFX01000019_gene2381	1.521e-287	887.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,2K0Q1@204457|Sphingomonadales	204457|Sphingomonadales	G	phosphomannomutase	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH3_k127_12554023_0	1248917.ANFX01000019_gene2385	0.0	1139.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2K0I6@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
WH3_k127_12567407_0	1479239.JQMU01000001_gene2724	0.0	1037.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,2K0KI@204457|Sphingomonadales	204457|Sphingomonadales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
WH3_k127_12567407_1	1479239.JQMU01000001_gene2723	2.453e-233	729.0	COG2234@1|root,COG2234@2|Bacteria,1MWBX@1224|Proteobacteria,2U2RE@28211|Alphaproteobacteria,2JZWX@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WH3_k127_12567407_2	1248917.ANFX01000008_gene243	1.185e-127	410.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,2K1F1@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
WH3_k127_12568597_6	1122970.AUHC01000020_gene2411	4.465e-57	201.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2TRZJ@28211|Alphaproteobacteria,2K1E6@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
WH3_k127_12568597_4	1502850.FG91_02569	2.073e-63	226.0	COG3219@1|root,COG3219@2|Bacteria,1Q7HA@1224|Proteobacteria,2VDNP@28211|Alphaproteobacteria,2K5KJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
WH3_k127_12568597_5	1122970.AUHC01000020_gene2413	1.695e-61	218.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2TVZ9@28211|Alphaproteobacteria,2K5X8@204457|Sphingomonadales	204457|Sphingomonadales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
WH3_k127_12568597_2	1122970.AUHC01000020_gene2414	9.917e-72	246.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2UA8J@28211|Alphaproteobacteria,2KC9V@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_12568597_1	1248917.ANFX01000012_gene1767	4.887e-76	260.0	COG4944@1|root,COG4944@2|Bacteria,1N3C7@1224|Proteobacteria,2VGWG@28211|Alphaproteobacteria,2K5Z0@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
WH3_k127_12568597_0	1502850.FG91_02578	5.445e-92	306.0	28Q4X@1|root,2ZCN0@2|Bacteria,1RA2A@1224|Proteobacteria,2U5RP@28211|Alphaproteobacteria,2K4DH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12568597_3	1044.EH31_06485	9.661e-66	234.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,2TW2S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,Cadherin_3,FecR,PPC,Peptidase_M10_C
WH3_k127_12568616_0	1479239.JQMU01000001_gene1249	0.0	1086.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2K0WP@204457|Sphingomonadales	204457|Sphingomonadales	E	glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
WH3_k127_12568616_2	1248917.ANFX01000013_gene1567	2.712e-190	599.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2TTR7@28211|Alphaproteobacteria,2K0NV@204457|Sphingomonadales	204457|Sphingomonadales	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
WH3_k127_12568616_4	1479239.JQMU01000001_gene1251	3.366e-113	372.0	COG0457@1|root,COG0457@2|Bacteria,1MYZ1@1224|Proteobacteria,2UCPV@28211|Alphaproteobacteria,2K4IW@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
WH3_k127_12568616_3	1248917.ANFX01000013_gene1569	5.845e-134	430.0	COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2K1F6@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
WH3_k127_12568616_1	1479239.JQMU01000001_gene1253	3.717e-290	897.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2U0FQ@28211|Alphaproteobacteria,2K06C@204457|Sphingomonadales	204457|Sphingomonadales	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
WH3_k127_12568616_6	1248917.ANFX01000013_gene1573	4.968e-30	119.0	COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,2UFFG@28211|Alphaproteobacteria,2K6RT@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
WH3_k127_12568616_5	1120705.FG95_02713	4.658e-41	157.0	2E2TJ@1|root,32XVS@2|Bacteria,1RJIC@1224|Proteobacteria,2U98P@28211|Alphaproteobacteria,2K59C@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1259754_0	1122970.AUHC01000002_gene1237	3.84e-190	597.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,2TR62@28211|Alphaproteobacteria,2K1KR@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WH3_k127_1259754_1	1122970.AUHC01000002_gene1268	1.007e-156	495.0	COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,2UMCM@28211|Alphaproteobacteria,2K3DW@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
WH3_k127_12667440_4	1479239.JQMU01000001_gene2479	2.39e-22	96.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,2K4ID@204457|Sphingomonadales	204457|Sphingomonadales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WH3_k127_12667440_1	1479239.JQMU01000001_gene2478	4.725e-169	533.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2K1V9@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WH3_k127_12667440_0	1479239.JQMU01000001_gene2477	3.026e-226	703.0	COG2267@1|root,COG2267@2|Bacteria,1MVDA@1224|Proteobacteria,2TUDQ@28211|Alphaproteobacteria,2K1MR@204457|Sphingomonadales	204457|Sphingomonadales	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
WH3_k127_12667440_3	1479239.JQMU01000001_gene2476	1.31e-88	293.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,2K4GA@204457|Sphingomonadales	204457|Sphingomonadales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WH3_k127_12667440_2	1122970.AUHC01000005_gene1875	1.022e-129	420.0	COG0446@1|root,COG0446@2|Bacteria,1RET8@1224|Proteobacteria,2U7WG@28211|Alphaproteobacteria,2K3G2@204457|Sphingomonadales	204457|Sphingomonadales	S	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12674631_0	1479239.JQMU01000001_gene333	1.845e-217	679.0	2BWFC@1|root,33R2I@2|Bacteria,1R42X@1224|Proteobacteria,2U4BF@28211|Alphaproteobacteria,2K0XT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12674631_3	1479239.JQMU01000001_gene332	8.48e-153	490.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,2K25K@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH3_k127_12674631_2	1479239.JQMU01000001_gene331	2.646e-181	569.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria,2K0BW@204457|Sphingomonadales	204457|Sphingomonadales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
WH3_k127_12674631_1	1479239.JQMU01000001_gene330	5.033e-204	642.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2TTU7@28211|Alphaproteobacteria,2K1IX@204457|Sphingomonadales	204457|Sphingomonadales	S	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M48
WH3_k127_12711336_0	1248917.ANFX01000032_gene914	1.325e-117	379.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,2K08A@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WH3_k127_12711336_2	1248917.ANFX01000032_gene913	2.907e-87	293.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,2K4HD@204457|Sphingomonadales	204457|Sphingomonadales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
WH3_k127_12711336_1	1479239.JQMU01000001_gene734	5.438e-101	330.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2K1J2@204457|Sphingomonadales	204457|Sphingomonadales	Q	dioxygenase	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
WH3_k127_12808867_0	1479239.JQMU01000001_gene499	3.485e-311	959.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,2K0GM@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
WH3_k127_12836093_4	1479239.JQMU01000001_gene2520	2.268e-31	123.0	COG2135@1|root,COG2135@2|Bacteria,1RABZ@1224|Proteobacteria,2U6AM@28211|Alphaproteobacteria,2K4CE@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
WH3_k127_12836093_3	158500.BV97_02311	5.384e-49	177.0	COG0346@1|root,COG0346@2|Bacteria,1N0XB@1224|Proteobacteria,2UD3M@28211|Alphaproteobacteria,2K66R@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
WH3_k127_12836093_2	685035.ADAE01000018_gene816	2.066e-67	232.0	COG0789@1|root,COG0789@2|Bacteria,1RH2U@1224|Proteobacteria,2U73A@28211|Alphaproteobacteria,2K4YD@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
WH3_k127_12836093_5	1122611.KB903963_gene4682	0.0001651	44.0	COG0339@1|root,COG0339@2|Bacteria,2GM2Z@201174|Actinobacteria,4EGUI@85012|Streptosporangiales	201174|Actinobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
WH3_k127_12836093_0	1479239.JQMU01000001_gene2536	1.424e-100	332.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,2K4JB@204457|Sphingomonadales	204457|Sphingomonadales	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WH3_k127_12836093_1	1479239.JQMU01000001_gene2537	1.152e-79	266.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2TUKS@28211|Alphaproteobacteria,2K15X@204457|Sphingomonadales	204457|Sphingomonadales	KL	Helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
WH3_k127_12845211_2	1479239.JQMU01000001_gene285	1.282e-135	433.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,2K0MC@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent DNA helicase RecG	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WH3_k127_12845211_5	1122970.AUHC01000001_gene835	3.597e-58	206.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2U72X@28211|Alphaproteobacteria,2K5E1@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WH3_k127_12845211_1	1479239.JQMU01000001_gene283	1.04e-282	872.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,2TSHG@28211|Alphaproteobacteria,2K1R5@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
WH3_k127_12845211_3	1248917.ANFX01000024_gene1182	1.855e-135	436.0	COG1028@1|root,COG1028@2|Bacteria,1MWGK@1224|Proteobacteria,2TVQ8@28211|Alphaproteobacteria,2K2DN@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_12845211_4	1479239.JQMU01000001_gene281	8.495e-74	250.0	2AM63@1|root,31C0H@2|Bacteria,1N4E2@1224|Proteobacteria,2UEUX@28211|Alphaproteobacteria,2K6WN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3429
WH3_k127_12845211_0	1479239.JQMU01000001_gene280	0.0	1115.0	COG2200@1|root,COG4252@1|root,COG2200@2|Bacteria,COG4252@2|Bacteria,1N299@1224|Proteobacteria,2U5C8@28211|Alphaproteobacteria,2K2WP@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL
WH3_k127_12845211_6	1183438.GKIL_2919	7.399e-52	189.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria	2|Bacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WH3_k127_128510_0	1479239.JQMU01000001_gene1548	1.715e-204	641.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria,2K1A6@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH3_k127_128510_1	1479239.JQMU01000001_gene1549	1.237e-135	437.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,2JZYQ@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_128510_2	1479239.JQMU01000001_gene1550	2.384e-76	259.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2U139@28211|Alphaproteobacteria,2K18J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
WH3_k127_12854655_0	1248760.ANFZ01000014_gene2053	0.0	1017.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2TSEQ@28211|Alphaproteobacteria,2K0P3@204457|Sphingomonadales	204457|Sphingomonadales	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,FAD_binding_3
WH3_k127_12854655_1	383381.EH30_02670	3.018e-278	863.0	COG4805@1|root,COG4805@2|Bacteria,1R84Q@1224|Proteobacteria,2TT6N@28211|Alphaproteobacteria,2K2ME@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WH3_k127_12854655_2	555793.WSK_2980	2.201e-129	417.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria,2K00Q@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	ligV	-	-	-	-	-	-	-	-	-	-	-	Aldedh
WH3_k127_12903767_1	1479239.JQMU01000001_gene2617	3.655e-150	477.0	COG5031@1|root,COG5031@2|Bacteria,1RE8M@1224|Proteobacteria,2U8V6@28211|Alphaproteobacteria,2K47N@204457|Sphingomonadales	204457|Sphingomonadales	H	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	-	-	-	-	-	-	-	-	-	-	-	-	Coq4
WH3_k127_12903767_2	1248917.ANFX01000008_gene367	4.04e-71	247.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria,2K5BZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
WH3_k127_12903767_0	1248917.ANFX01000008_gene366	7.517e-298	915.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WH3_k127_12907131_4	1248917.ANFX01000008_gene359	7.313e-89	297.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U685@28211|Alphaproteobacteria,2KCVW@204457|Sphingomonadales	204457|Sphingomonadales	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
WH3_k127_12907131_3	1479239.JQMU01000001_gene2623	6.031e-101	332.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2U74H@28211|Alphaproteobacteria,2K1RJ@204457|Sphingomonadales	204457|Sphingomonadales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WH3_k127_12907131_1	1248917.ANFX01000008_gene362	7.675e-165	524.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,2K19H@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WH3_k127_12907131_6	1479239.JQMU01000001_gene2621	4.715e-37	141.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,2K6WZ@204457|Sphingomonadales	204457|Sphingomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WH3_k127_12907131_5	1479239.JQMU01000001_gene2620	1.279e-72	247.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,2UBSF@28211|Alphaproteobacteria,2K61I@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
WH3_k127_12907131_2	1479239.JQMU01000001_gene2619	2.083e-127	409.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria,2UEFT@28211|Alphaproteobacteria,2K4KH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12907131_0	1248917.ANFX01000008_gene366	7.844e-247	764.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WH3_k127_12911729_0	1479239.JQMU01000001_gene719	1.516e-212	663.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,2K0DV@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
WH3_k127_12911729_1	1479239.JQMU01000001_gene718	9.394e-118	383.0	29BA9@1|root,2ZY8N@2|Bacteria,1RJEZ@1224|Proteobacteria,2U9H3@28211|Alphaproteobacteria,2K4P7@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
WH3_k127_12911729_2	237727.NAP1_08010	4.357e-50	182.0	2BVJ7@1|root,32QX6@2|Bacteria,1N7C0@1224|Proteobacteria,2UGAW@28211|Alphaproteobacteria,2K789@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
WH3_k127_12922050_3	1248917.ANFX01000037_gene2052	6.691e-21	91.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,2JZW3@204457|Sphingomonadales	204457|Sphingomonadales	C	Heme copper-type cytochrome quinol oxidase, subunit 3	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
WH3_k127_12922050_2	1122970.AUHC01000005_gene1861	2.999e-49	178.0	COG5349@1|root,COG5349@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
WH3_k127_12922050_1	383381.EH30_02915	1.624e-70	247.0	COG3346@1|root,COG3346@2|Bacteria,1RIJQ@1224|Proteobacteria,2UA1G@28211|Alphaproteobacteria,2K34C@204457|Sphingomonadales	204457|Sphingomonadales	S	SURF1-like protein	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
WH3_k127_12922050_0	1479239.JQMU01000001_gene2491	7.842e-168	529.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2TT0D@28211|Alphaproteobacteria,2K0KX@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
WH3_k127_12929212_12	1248917.ANFX01000012_gene1885	2.551e-18	85.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,2K1N2@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH3_k127_12929212_2	1248917.ANFX01000012_gene1884	1.605e-262	818.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,2K12F@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH3_k127_12929212_0	1479239.JQMU01000001_gene2293	5e-324	998.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,2K0Y2@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
WH3_k127_12929212_8	1479239.JQMU01000001_gene2292	9.289e-84	282.0	2AK00@1|root,32PGE@2|Bacteria,1NEPB@1224|Proteobacteria,2UFQJ@28211|Alphaproteobacteria,2KDE4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12929212_4	1479239.JQMU01000001_gene2291	2.718e-170	541.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,2K178@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WH3_k127_12929212_7	1479239.JQMU01000001_gene2290	2.863e-86	287.0	COG2001@1|root,COG2001@2|Bacteria,1RHCS@1224|Proteobacteria,2UJTK@28211|Alphaproteobacteria,2KD5Y@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	-
WH3_k127_12929212_6	1479239.JQMU01000001_gene2289	6.852e-87	298.0	COG3225@1|root,COG3225@2|Bacteria,1NC9C@1224|Proteobacteria,2UH50@28211|Alphaproteobacteria,2K6HE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
WH3_k127_12929212_11	1479239.JQMU01000001_gene2288	2.794e-38	147.0	2BNY5@1|root,32HN6@2|Bacteria,1NPJR@1224|Proteobacteria,2UMBD@28211|Alphaproteobacteria,2K80A@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12929212_3	1248917.ANFX01000012_gene1877	1.394e-207	649.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,2K0XR@204457|Sphingomonadales	204457|Sphingomonadales	E	Cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH3_k127_12929212_10	1248917.ANFX01000012_gene1876	5.196e-54	192.0	2E3QV@1|root,32YNP@2|Bacteria,1N57A@1224|Proteobacteria,2UEEC@28211|Alphaproteobacteria,2K665@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
WH3_k127_12929212_9	1479239.JQMU01000001_gene2286	4.136e-59	209.0	COG0633@1|root,COG0633@2|Bacteria,1N261@1224|Proteobacteria,2UC7B@28211|Alphaproteobacteria,2K5DE@204457|Sphingomonadales	204457|Sphingomonadales	C	ferredoxin	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
WH3_k127_12929212_5	1122970.AUHC01000005_gene2061	7.46e-116	375.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,2K0I0@204457|Sphingomonadales	204457|Sphingomonadales	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WH3_k127_12929212_1	1479239.JQMU01000001_gene2284	4.369e-307	946.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUZZ@28211|Alphaproteobacteria,2K37J@204457|Sphingomonadales	204457|Sphingomonadales	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WH3_k127_12929653_6	1380380.JIAX01000009_gene1314	9.373e-37	151.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
WH3_k127_12929653_5	383381.EH30_00235	1.553e-74	257.0	COG1309@1|root,COG1309@2|Bacteria,1PDZ8@1224|Proteobacteria,2UC3D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
WH3_k127_12929653_1	383381.EH30_00230	0.0	1297.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TVPT@28211|Alphaproteobacteria,2K2IS@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_12929653_4	383381.EH30_00225	2.205e-97	331.0	COG0657@1|root,COG0657@2|Bacteria,1R4BT@1224|Proteobacteria,2U6SA@28211|Alphaproteobacteria,2K2VW@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WH3_k127_12929653_3	1248917.ANFX01000035_gene1991	1.691e-129	418.0	COG0730@1|root,COG0730@2|Bacteria,1PGTZ@1224|Proteobacteria,2U5IZ@28211|Alphaproteobacteria,2K1II@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH3_k127_12929653_7	1248917.ANFX01000035_gene1992	0.0007807	45.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2TWA4@28211|Alphaproteobacteria,2KEDC@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_12929653_0	1122970.AUHC01000009_gene232	0.0	1709.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria,2KEEP@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_12929653_2	1479239.JQMU01000001_gene375	1.212e-139	447.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR78@28211|Alphaproteobacteria,2K2PQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_12943017_0	1479239.JQMU01000001_gene309	0.0	1394.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,2K06P@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
WH3_k127_12943017_1	314225.ELI_05060	1.244e-30	121.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria,2K1HH@204457|Sphingomonadales	204457|Sphingomonadales	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTP_transferase
WH3_k127_12954761_7	1479239.JQMU01000001_gene1276	9.715e-79	264.0	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,2TRXV@28211|Alphaproteobacteria,2K1B3@204457|Sphingomonadales	204457|Sphingomonadales	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
WH3_k127_12954761_9	1122970.AUHC01000002_gene1236	1.017e-58	209.0	2DMJE@1|root,32RYR@2|Bacteria,1N7PS@1224|Proteobacteria,2UFEW@28211|Alphaproteobacteria,2K57K@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
WH3_k127_12954761_0	1479239.JQMU01000001_gene1278	8.361e-236	738.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,2K08U@204457|Sphingomonadales	204457|Sphingomonadales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WH3_k127_12954761_11	1122970.AUHC01000002_gene1234	1.087e-41	155.0	29W6B@1|root,30HRE@2|Bacteria,1NB66@1224|Proteobacteria,2UGIS@28211|Alphaproteobacteria,2K738@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WH3_k127_12954761_5	1479239.JQMU01000001_gene1280	3.114e-87	290.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,2K4GE@204457|Sphingomonadales	204457|Sphingomonadales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
WH3_k127_12954761_10	1479239.JQMU01000001_gene1281	7.142e-47	170.0	COG0790@1|root,COG0790@2|Bacteria,1N8SR@1224|Proteobacteria,2UFFQ@28211|Alphaproteobacteria,2K5VX@204457|Sphingomonadales	204457|Sphingomonadales	S	FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
WH3_k127_12954761_1	1479239.JQMU01000001_gene1282	5.478e-232	720.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2K1NQ@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
WH3_k127_12954761_2	1122970.AUHC01000002_gene1230	1.056e-129	417.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2TV1D@28211|Alphaproteobacteria,2K3TX@204457|Sphingomonadales	204457|Sphingomonadales	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
WH3_k127_12954761_6	1248917.ANFX01000019_gene2309	1.131e-80	271.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,2K4U7@204457|Sphingomonadales	204457|Sphingomonadales	J	endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
WH3_k127_12954761_3	1479239.JQMU01000001_gene1285	9.304e-128	410.0	COG0647@1|root,COG0647@2|Bacteria,1RBCP@1224|Proteobacteria,2U6MG@28211|Alphaproteobacteria,2KDJX@204457|Sphingomonadales	204457|Sphingomonadales	G	UMP catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12954761_12	1479239.JQMU01000001_gene1286	1.525e-28	123.0	2DMKE@1|root,32S6E@2|Bacteria,1NH3D@1224|Proteobacteria,2UHAS@28211|Alphaproteobacteria,2K72S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3572
WH3_k127_12954761_8	1479239.JQMU01000001_gene1287	4.782e-60	209.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,2K53C@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WH3_k127_12954761_4	1248917.ANFX01000019_gene2305	1.517e-92	310.0	COG1418@1|root,COG1418@2|Bacteria,1RGE5@1224|Proteobacteria,2U8QJ@28211|Alphaproteobacteria,2K54J@204457|Sphingomonadales	204457|Sphingomonadales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_12954761_13	1479239.JQMU01000001_gene1289	1.077e-09	60.0	COG0236@1|root,COG0236@2|Bacteria,1NHQD@1224|Proteobacteria,2UGSG@28211|Alphaproteobacteria,2K5YB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
WH3_k127_12996196_0	1479239.JQMU01000001_gene1393	1.45e-215	671.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K001@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WH3_k127_12996196_6	1479239.JQMU01000001_gene1392	7.285e-62	218.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria,2K66W@204457|Sphingomonadales	204457|Sphingomonadales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WH3_k127_12996196_2	1248917.ANFX01000005_gene89	1.74e-172	548.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2K148@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH3_k127_12996196_1	1122970.AUHC01000010_gene1583	3.987e-211	665.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,2K0DR@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH3_k127_12996196_3	1248917.ANFX01000026_gene1066	4.762e-125	403.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2U6ZC@28211|Alphaproteobacteria,2K3WB@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WH3_k127_12996196_5	1479239.JQMU01000001_gene1388	4.162e-70	241.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2UBSV@28211|Alphaproteobacteria,2K55D@204457|Sphingomonadales	204457|Sphingomonadales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WH3_k127_12996196_4	1248917.ANFX01000026_gene1064	1.349e-78	267.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2U95Q@28211|Alphaproteobacteria,2K4F0@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WH3_k127_12996196_7	1479239.JQMU01000001_gene1386	1.273e-07	55.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2TUSP@28211|Alphaproteobacteria,2K22Y@204457|Sphingomonadales	204457|Sphingomonadales	D	Membrane-bound metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH3_k127_13016418_1	1479239.JQMU01000001_gene1529	6.783e-157	501.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,2JZUH@204457|Sphingomonadales	204457|Sphingomonadales	G	in Escherichia coli this protein forms a dimer and binds manganese	glpX	-	3.1.3.11,3.1.3.37	ko:K11532	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
WH3_k127_13016418_2	1479239.JQMU01000001_gene1530	7.688e-86	291.0	2ADW2@1|root,313N2@2|Bacteria,1P7QE@1224|Proteobacteria,2UWBG@28211|Alphaproteobacteria,2KBQC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13016418_0	1479239.JQMU01000001_gene1531	3.053e-182	572.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,2K2BW@204457|Sphingomonadales	204457|Sphingomonadales	E	homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
WH3_k127_13026318_1	1479239.JQMU01000001_gene303	1.439e-89	296.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,2K1MX@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WH3_k127_13026318_0	1248917.ANFX01000024_gene1166	3.097e-126	408.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria,2K4T4@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH3_k127_13026318_2	1123020.AUIE01000047_gene1784	7.127e-19	98.0	COG2391@1|root,COG2391@2|Bacteria,1NADV@1224|Proteobacteria,1T5T5@1236|Gammaproteobacteria,1YHAM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WH3_k127_13035866_0	1479239.JQMU01000001_gene1133	6.365e-154	490.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,2K0BX@204457|Sphingomonadales	204457|Sphingomonadales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WH3_k127_13035866_2	1479239.JQMU01000001_gene1134	2.71e-127	410.0	COG1994@1|root,COG1994@2|Bacteria,1N5AF@1224|Proteobacteria,2UZIF@28211|Alphaproteobacteria,2K8Y5@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
WH3_k127_13035866_5	1479239.JQMU01000001_gene1135	3.882e-82	276.0	COG5517@1|root,COG5517@2|Bacteria,1NDVD@1224|Proteobacteria,2VGRK@28211|Alphaproteobacteria,2K37V@204457|Sphingomonadales	204457|Sphingomonadales	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
WH3_k127_13035866_3	1479239.JQMU01000001_gene1136	7.52e-119	387.0	COG1309@1|root,COG1309@2|Bacteria,1R44G@1224|Proteobacteria,2TTF0@28211|Alphaproteobacteria,2K576@204457|Sphingomonadales	204457|Sphingomonadales	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WH3_k127_13035866_1	1122970.AUHC01000012_gene916	7.18e-141	452.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2TTEP@28211|Alphaproteobacteria,2K2P6@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WH3_k127_13035866_4	291985.CCSI01000002_gene1679	1.767e-85	287.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,2U5TA@28211|Alphaproteobacteria,2K48I@204457|Sphingomonadales	204457|Sphingomonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WH3_k127_13082134_1	1479239.JQMU01000001_gene649	1.061e-139	450.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,2U1WU@28211|Alphaproteobacteria,2K1HS@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WH3_k127_13082134_0	1479239.JQMU01000001_gene650	9.148e-161	509.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,2K0K9@204457|Sphingomonadales	204457|Sphingomonadales	C	Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane	dctA	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
WH3_k127_13103817_0	1545915.JROG01000004_gene2067	1.656e-277	858.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,2K18V@204457|Sphingomonadales	204457|Sphingomonadales	C	Transketolase, thiamine diphosphate binding domain	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N
WH3_k127_13103817_2	247634.GPB2148_1932	6.118e-94	314.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,1RSP4@1236|Gammaproteobacteria,1J604@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_13103817_1	1248917.ANFX01000040_gene798	9.768e-129	415.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,2K382@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH3_k127_13103817_3	1248917.ANFX01000040_gene797	4.169e-51	181.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2JZXP@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WH3_k127_13135885_1	1479239.JQMU01000001_gene2526	3.459e-135	432.0	COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,2TSBV@28211|Alphaproteobacteria,2K1Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
WH3_k127_13135885_2	1479239.JQMU01000001_gene2527	1.475e-126	407.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TU1Z@28211|Alphaproteobacteria,2K0UW@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
WH3_k127_13135885_0	1479239.JQMU01000001_gene2528	0.0	1923.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,2TRU5@28211|Alphaproteobacteria,2K20A@204457|Sphingomonadales	204457|Sphingomonadales	EI	Allophanate hydrolase subunit 2	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
WH3_k127_13141351_0	1248917.ANFX01000022_gene680	3.025e-255	789.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2K0J0@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
WH3_k127_13141351_1	1479239.JQMU01000001_gene2346	2.467e-29	120.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2TSVG@28211|Alphaproteobacteria,2K0AG@204457|Sphingomonadales	204457|Sphingomonadales	E	tRNA synthetase, class II	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
WH3_k127_13168268_1	1479239.JQMU01000001_gene865	1.995e-202	634.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2K17H@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WH3_k127_13168268_0	1479239.JQMU01000001_gene864	6.078e-252	779.0	COG0654@1|root,COG0654@2|Bacteria,1N8DE@1224|Proteobacteria,2TU88@28211|Alphaproteobacteria,2K0B6@204457|Sphingomonadales	204457|Sphingomonadales	CH	Lycopene cyclase protein	-	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
WH3_k127_13168268_2	1044.EH31_05880	2.957e-16	80.0	COG3713@1|root,COG3713@2|Bacteria,1RF1U@1224|Proteobacteria,2U8SJ@28211|Alphaproteobacteria,2K4FB@204457|Sphingomonadales	204457|Sphingomonadales	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
WH3_k127_13183300_5	1248917.ANFX01000035_gene1943	4.934e-05	48.0	COG1132@1|root,COG1132@2|Bacteria,1R8US@1224|Proteobacteria,2U32E@28211|Alphaproteobacteria,2K2WF@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WH3_k127_13183300_3	237727.NAP1_11533	4.598e-52	201.0	2C8KX@1|root,32RMF@2|Bacteria,1N68G@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
WH3_k127_13183300_0	1248917.ANFX01000035_gene1945	4.22e-176	555.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2TQPI@28211|Alphaproteobacteria,2K0S0@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH3_k127_13183300_2	1248917.ANFX01000035_gene1946	1.749e-105	345.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2U7G8@28211|Alphaproteobacteria,2K456@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
WH3_k127_13183300_1	1248917.ANFX01000035_gene1947	7.365e-133	428.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2TSP6@28211|Alphaproteobacteria,2K002@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WH3_k127_13183300_4	314285.KT71_04435	2.727e-45	166.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,1J7FQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Male sterility protein	rmlB	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WH3_k127_13213106_3	85643.Tmz1t_0373	6.004e-68	231.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VNSH@28216|Betaproteobacteria,2KYPA@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
WH3_k127_13213106_0	85643.Tmz1t_0372	6.573e-262	808.0	COG4974@1|root,COG4974@2|Bacteria,1QUHS@1224|Proteobacteria,2VM8C@28216|Betaproteobacteria,2KYHS@206389|Rhodocyclales	206389|Rhodocyclales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
WH3_k127_13213106_2	85643.Tmz1t_0371	5.185e-208	648.0	COG0582@1|root,COG0582@2|Bacteria,1NX90@1224|Proteobacteria,2VJRU@28216|Betaproteobacteria,2KXTA@206389|Rhodocyclales	206389|Rhodocyclales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
WH3_k127_13213106_1	85643.Tmz1t_0370	2.03e-210	655.0	COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2VICA@28216|Betaproteobacteria,2M00E@206389|Rhodocyclales	206389|Rhodocyclales	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
WH3_k127_13213106_4	85643.Tmz1t_0373	1.001e-26	109.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VNSH@28216|Betaproteobacteria,2KYPA@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
WH3_k127_1322350_0	1479239.JQMU01000001_gene2188	4.035e-298	917.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2TQXA@28211|Alphaproteobacteria,2K20G@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
WH3_k127_1322350_1	291985.CCSI01000004_gene609	9.844e-157	503.0	COG0738@1|root,COG0738@2|Bacteria,1MXDC@1224|Proteobacteria,2TSVP@28211|Alphaproteobacteria,2K028@204457|Sphingomonadales	204457|Sphingomonadales	G	Transporter	-	-	-	ko:K02429	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
WH3_k127_13243179_2	1248917.ANFX01000050_gene628	8.005e-116	376.0	COG1738@1|root,COG1738@2|Bacteria,1RJV6@1224|Proteobacteria,2U7IX@28211|Alphaproteobacteria,2K2CH@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
WH3_k127_13243179_0	1479239.JQMU01000001_gene1032	1.563e-261	812.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,2K07T@204457|Sphingomonadales	204457|Sphingomonadales	F	nucleoside	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
WH3_k127_13243179_1	1479239.JQMU01000001_gene1031	4.56e-187	586.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,2TU3Y@28211|Alphaproteobacteria,2K1Y3@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
WH3_k127_13243179_3	1122970.AUHC01000002_gene1401	1.495e-54	196.0	COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,2TSK9@28211|Alphaproteobacteria,2K0T9@204457|Sphingomonadales	204457|Sphingomonadales	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
WH3_k127_13251059_1	1248917.ANFX01000012_gene1891	1.436e-190	596.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,2K0QA@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WH3_k127_13251059_0	1479239.JQMU01000001_gene2302	6.396e-196	620.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,2K0W3@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WH3_k127_13251059_2	161528.ED21_30714	5.786e-89	302.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,2K1JE@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
WH3_k127_13251059_3	1479239.JQMU01000001_gene2304	7.216e-45	164.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,2K082@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WH3_k127_13271917_1	1248916.ANFY01000011_gene1227	1.008e-18	87.0	COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2U97G@28211|Alphaproteobacteria,2K59G@204457|Sphingomonadales	204457|Sphingomonadales	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH3_k127_13271917_0	158500.BV97_02944	7.395e-172	552.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,2TVIR@28211|Alphaproteobacteria,2KC5I@204457|Sphingomonadales	204457|Sphingomonadales	L	hmm pf01609	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	-
WH3_k127_13271917_2	1207055.C100_08380	3.583e-06	49.0	COG1541@1|root,COG1541@2|Bacteria,1NT0G@1224|Proteobacteria,2UP2C@28211|Alphaproteobacteria,2K3RG@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13358429_2	1248917.ANFX01000037_gene2046	4.611e-42	154.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,2TUX2@28211|Alphaproteobacteria,2K1QD@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
WH3_k127_13358429_0	383381.EH30_02870	4.165e-134	437.0	COG1680@1|root,COG1680@2|Bacteria,1R60I@1224|Proteobacteria,2TV80@28211|Alphaproteobacteria,2K08P@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WH3_k127_13358429_1	1248917.ANFX01000037_gene2044	1.438e-71	243.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,2K0T4@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
WH3_k127_13385756_2	1479239.JQMU01000001_gene845	1.286e-80	269.0	COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,2UC83@28211|Alphaproteobacteria,2K5XY@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
WH3_k127_13385756_0	1479239.JQMU01000001_gene844	1.324e-230	724.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,2U1FI@28211|Alphaproteobacteria,2K0WR@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
WH3_k127_13385756_1	1248917.ANFX01000020_gene2262	2.475e-104	346.0	COG1881@1|root,COG1881@2|Bacteria,1RHPA@1224|Proteobacteria,2UMUY@28211|Alphaproteobacteria,2K4WS@204457|Sphingomonadales	204457|Sphingomonadales	S	Phosphatidylethanolamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP
WH3_k127_13385756_5	1248917.ANFX01000020_gene2261	2.125e-44	161.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2UHFX@28211|Alphaproteobacteria,2K6VN@204457|Sphingomonadales	204457|Sphingomonadales	B	COG5531 SWIB-domain-containing proteins implicated in chromatin remodeling	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
WH3_k127_13385756_4	1479239.JQMU01000001_gene841	1.28e-58	209.0	COG4270@1|root,COG4270@2|Bacteria,1N1BK@1224|Proteobacteria,2UDCR@28211|Alphaproteobacteria,2KCAE@204457|Sphingomonadales	204457|Sphingomonadales	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
WH3_k127_13385756_3	1479239.JQMU01000001_gene840	1.943e-73	250.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2U962@28211|Alphaproteobacteria,2K544@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
WH3_k127_13385756_6	1479239.JQMU01000001_gene839	6.04e-18	91.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2K0GT@204457|Sphingomonadales	204457|Sphingomonadales	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WH3_k127_13418763_3	1479239.JQMU01000001_gene1570	5.409e-48	171.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2K21X@204457|Sphingomonadales	204457|Sphingomonadales	L	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N_2,ADH_zinc_N
WH3_k127_13418763_1	1479239.JQMU01000001_gene1569	1.784e-113	371.0	COG3828@1|root,COG3828@2|Bacteria,1RHWH@1224|Proteobacteria,2UBAF@28211|Alphaproteobacteria,2K2JF@204457|Sphingomonadales	204457|Sphingomonadales	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
WH3_k127_13418763_2	1248917.ANFX01000019_gene2327	3.123e-61	218.0	COG4308@1|root,COG4308@2|Bacteria,1NANW@1224|Proteobacteria,2UISS@28211|Alphaproteobacteria,2K62K@204457|Sphingomonadales	204457|Sphingomonadales	Q	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
WH3_k127_13418763_0	1248917.ANFX01000019_gene2326	1.403e-139	445.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2K2HH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_13418763_4	509635.N824_00710	0.0004578	51.0	28JHT@1|root,2Z9BA@2|Bacteria	2|Bacteria	S	Domain of Unknown Function with PDB structure (DUF3864)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3863,DUF3864
WH3_k127_13468558_3	1479239.JQMU01000001_gene1053	7.285e-85	281.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U5Q0@28211|Alphaproteobacteria,2KD5R@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	-	-	-	-	-	-	-	-	-	-	SelR
WH3_k127_13468558_1	1479239.JQMU01000001_gene1054	6.23e-138	439.0	COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,2K1DG@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
WH3_k127_13468558_6	1122970.AUHC01000002_gene1378	8e-34	135.0	29C68@1|root,2ZZ4T@2|Bacteria,1NBHC@1224|Proteobacteria,2UFKP@28211|Alphaproteobacteria,2K7CY@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13468558_4	1248917.ANFX01000050_gene648	1.1e-68	235.0	COG0346@1|root,COG0346@2|Bacteria,1RH8G@1224|Proteobacteria,2U9BR@28211|Alphaproteobacteria,2K5AH@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH3_k127_13468558_2	1248917.ANFX01000049_gene1622	9.182e-115	374.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2TTNQ@28211|Alphaproteobacteria,2K0KH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
WH3_k127_13468558_5	685035.ADAE01000008_gene2914	6.633e-53	190.0	COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,2UDE0@28211|Alphaproteobacteria,2KEPV@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WH3_k127_13468558_0	1248917.ANFX01000049_gene1623	8.792e-222	691.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2TQYA@28211|Alphaproteobacteria,2JZX2@204457|Sphingomonadales	204457|Sphingomonadales	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
WH3_k127_13468558_7	1479239.JQMU01000001_gene1059	1.158e-14	77.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,2JZXY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_13491596_1	1479239.JQMU01000001_gene2598	1.934e-157	500.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2TR46@28211|Alphaproteobacteria,2K1ZG@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
WH3_k127_13491596_0	1479239.JQMU01000001_gene2599	0.0	1061.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,2K0VW@204457|Sphingomonadales	204457|Sphingomonadales	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WH3_k127_13491596_4	1479239.JQMU01000001_gene2600	1.623e-73	254.0	COG0655@1|root,COG0655@2|Bacteria,1RAP5@1224|Proteobacteria,2U5P2@28211|Alphaproteobacteria,2KA9S@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0655 Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13491596_2	1479239.JQMU01000001_gene2601	1.329e-111	368.0	2AKK9@1|root,31BCH@2|Bacteria,1Q771@1224|Proteobacteria,2VDBG@28211|Alphaproteobacteria,2K8ID@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13491596_3	1479239.JQMU01000001_gene2602	9.002e-83	277.0	2A22K@1|root,30QCN@2|Bacteria,1NZ4F@1224|Proteobacteria,2UYZ4@28211|Alphaproteobacteria,2KA9D@204457|Sphingomonadales	204457|Sphingomonadales	S	A nuclease family of the HNH/ENDO VII superfamily with conserved AHH	-	-	-	-	-	-	-	-	-	-	-	-	AHH
WH3_k127_13513109_3	1122970.AUHC01000016_gene2588	1.208e-20	96.0	COG1320@1|root,COG1320@2|Bacteria,1MZ6Z@1224|Proteobacteria,2UD2X@28211|Alphaproteobacteria,2K4GK@204457|Sphingomonadales	204457|Sphingomonadales	P	Na+/H+ antiporter subunit	phaG	-	-	ko:K05564	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	PhaG_MnhG_YufB
WH3_k127_13513109_2	1479239.JQMU01000001_gene1618	5.958e-34	139.0	COG2212@1|root,COG2212@2|Bacteria,1N8WJ@1224|Proteobacteria,2UBVQ@28211|Alphaproteobacteria,2K685@204457|Sphingomonadales	204457|Sphingomonadales	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	phaF	-	-	ko:K05563	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MrpF_PhaF
WH3_k127_13513109_1	1479239.JQMU01000001_gene1617	9.735e-79	265.0	COG1863@1|root,COG1863@2|Bacteria,1RH9F@1224|Proteobacteria,2U9P6@28211|Alphaproteobacteria,2K4CB@204457|Sphingomonadales	204457|Sphingomonadales	P	Na+/H+ ion antiporter subunit	phaE	-	-	ko:K05562	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	MNHE
WH3_k127_13513109_0	1479239.JQMU01000001_gene1616	2.036e-198	624.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,2K334@204457|Sphingomonadales	204457|Sphingomonadales	CP	Proton-conducting membrane transporter	phaD	-	-	ko:K05561	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M
WH3_k127_13634642_1	1479239.JQMU01000001_gene2381	2.742e-146	466.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,2TT4Y@28211|Alphaproteobacteria,2K16F@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WH3_k127_13634642_3	1479239.JQMU01000001_gene2382	2.438e-35	141.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2UC0H@28211|Alphaproteobacteria,2K638@204457|Sphingomonadales	204457|Sphingomonadales	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
WH3_k127_13634642_2	1479239.JQMU01000001_gene2383	1.044e-74	254.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,2K4MZ@204457|Sphingomonadales	204457|Sphingomonadales	G	PTS fructose transporter subunit IIA	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
WH3_k127_13634642_0	1479239.JQMU01000001_gene2384	4.021e-174	550.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2TTI4@28211|Alphaproteobacteria,2K01M@204457|Sphingomonadales	204457|Sphingomonadales	T	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
WH3_k127_13634642_4	1479239.JQMU01000001_gene2385	2.665e-11	64.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2UFPB@28211|Alphaproteobacteria,2K65M@204457|Sphingomonadales	204457|Sphingomonadales	T	Serine kinase of the HPr protein, regulates carbohydrate metabolism	-	-	-	-	-	-	-	-	-	-	-	-	Hpr_kinase_C
WH3_k127_13701588_2	1122970.AUHC01000001_gene755	7.39e-30	120.0	COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,2TW2A@28211|Alphaproteobacteria,2KEGA@204457|Sphingomonadales	204457|Sphingomonadales	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
WH3_k127_13701588_0	1248917.ANFX01000027_gene1084	3.3e-227	711.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2U10Y@28211|Alphaproteobacteria,2K258@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
WH3_k127_13701588_1	1479239.JQMU01000001_gene247	1.141e-31	126.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2TQP2@28211|Alphaproteobacteria,2K0YS@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH3_k127_13706557_1	1248916.ANFY01000008_gene2107	3.197e-22	97.0	2BRAY@1|root,32K9G@2|Bacteria,1NJMM@1224|Proteobacteria,2V9YT@28211|Alphaproteobacteria,2KBYT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13706557_0	1248917.ANFX01000045_gene1280	0.0	1058.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,2U2QG@28211|Alphaproteobacteria,2K7CB@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
WH3_k127_13732508_0	1479239.JQMU01000001_gene2758	1.854e-86	289.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,2K40Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
WH3_k127_13732508_1	1479239.JQMU01000001_gene2757	1.38e-79	273.0	2AM6R@1|root,31C1C@2|Bacteria,1NP11@1224|Proteobacteria,2UKD9@28211|Alphaproteobacteria,2K72K@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_13732508_2	1479239.JQMU01000001_gene2756	1.404e-53	189.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2K0Y0@204457|Sphingomonadales	204457|Sphingomonadales	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
WH3_k127_13737155_1	383381.EH30_11845	8.558e-135	434.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,2TUWX@28211|Alphaproteobacteria,2K1T7@204457|Sphingomonadales	204457|Sphingomonadales	GK	Transcriptional regulator sugar kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
WH3_k127_13737155_0	383381.EH30_11840	4.584e-168	534.0	COG1621@1|root,COG1621@2|Bacteria,1PIQ9@1224|Proteobacteria,2UCAU@28211|Alphaproteobacteria,2K0FA@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glycosyl hydrolase 68 family	sacB	GO:0005575,GO:0005576	2.4.1.10,3.2.1.26	ko:K00692,ko:K01193	ko00052,ko00500,ko01100,ko02020,map00052,map00500,map01100,map02020	-	R00801,R00802,R02410,R03635,R03921,R05140,R06088	RC00028,RC00077	ko00000,ko00001,ko01000,ko01003	-	GH32,GH68	-	Glyco_hydro_68
WH3_k127_13737155_2	1248917.ANFX01000012_gene1770	8.148e-12	64.0	COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,1MXVP@1224|Proteobacteria,2TTT1@28211|Alphaproteobacteria,2K0D4@204457|Sphingomonadales	204457|Sphingomonadales	HP	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_13830700_0	1479239.JQMU01000001_gene2403	1.085e-158	504.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,2K1SR@204457|Sphingomonadales	204457|Sphingomonadales	J	Polynucleotide adenylyltransferase	cca	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd
WH3_k127_13830700_3	1044.EH31_07735	1.478e-85	291.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,2K3ZW@204457|Sphingomonadales	204457|Sphingomonadales	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH3_k127_13830700_1	1479239.JQMU01000001_gene2405	5.376e-100	328.0	COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,2U7DA@28211|Alphaproteobacteria,2K0YC@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09986	-	-	-	-	ko00000	-	-	-	DUF1285
WH3_k127_13830700_2	1248917.ANFX01000038_gene578	3.197e-95	313.0	COG3153@1|root,COG3153@2|Bacteria,1RD0C@1224|Proteobacteria,2U7AS@28211|Alphaproteobacteria,2K560@204457|Sphingomonadales	204457|Sphingomonadales	S	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
WH3_k127_138715_9	1248917.ANFX01000021_gene1690	2.157e-11	64.0	COG3000@1|root,COG3000@2|Bacteria,1R646@1224|Proteobacteria,2U1PJ@28211|Alphaproteobacteria,2K0N0@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH3_k127_138715_5	1550073.JROH01000011_gene2082	4.56e-71	248.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2TVFG@28211|Alphaproteobacteria,2K5NC@204457|Sphingomonadales	204457|Sphingomonadales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
WH3_k127_138715_7	392499.Swit_0878	6.088e-46	173.0	COG5478@1|root,COG5478@2|Bacteria,1MZMZ@1224|Proteobacteria,2UBR2@28211|Alphaproteobacteria,2K5A3@204457|Sphingomonadales	204457|Sphingomonadales	S	small integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
WH3_k127_138715_2	1479239.JQMU01000001_gene1632	1.435e-237	737.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K0V0@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_138715_4	1479239.JQMU01000001_gene1631	6.984e-92	304.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria,2K42H@204457|Sphingomonadales	204457|Sphingomonadales	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
WH3_k127_138715_1	1479239.JQMU01000001_gene1630	4.878e-265	819.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2TT7I@28211|Alphaproteobacteria,2JZV1@204457|Sphingomonadales	204457|Sphingomonadales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WH3_k127_138715_8	1479239.JQMU01000001_gene1629	7.64e-20	93.0	2A66B@1|root,30UYU@2|Bacteria,1PP6U@1224|Proteobacteria,2V1PY@28211|Alphaproteobacteria,2KBUZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_138715_3	1479239.JQMU01000001_gene1628	5.96e-237	740.0	COG0438@1|root,COG0438@2|Bacteria,1PDR7@1224|Proteobacteria,2U1R4@28211|Alphaproteobacteria,2K0MZ@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
WH3_k127_138715_6	1479239.JQMU01000001_gene1627	2.772e-60	220.0	2AM8G@1|root,31C3A@2|Bacteria,1Q81M@1224|Proteobacteria,2VE78@28211|Alphaproteobacteria,2KB0T@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_138715_0	1248917.ANFX01000041_gene1730	0.0	1744.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,2K19P@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
WH3_k127_1437450_0	1479239.JQMU01000001_gene291	9.133e-145	462.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria,2K0E6@204457|Sphingomonadales	204457|Sphingomonadales	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	ppnK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WH3_k127_1437450_1	1122970.AUHC01000001_gene841	2.909e-67	231.0	COG2200@1|root,COG2200@2|Bacteria,1R65R@1224|Proteobacteria,2U2PH@28211|Alphaproteobacteria,2K0M8@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WH3_k127_148010_1	1120705.FG95_03059	1.436e-80	278.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2TRZJ@28211|Alphaproteobacteria,2K1E6@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
WH3_k127_148010_3	1502850.FG91_02566	6.09e-34	133.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2UBV0@28211|Alphaproteobacteria,2K6TQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted integral membrane protein (DUF2282)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
WH3_k127_148010_0	279238.Saro_2305	6.443e-83	285.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2UAW0@28211|Alphaproteobacteria,2K2UB@204457|Sphingomonadales	204457|Sphingomonadales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	gspO	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WH3_k127_148010_2	1382303.JPOM01000001_gene1028	1.405e-40	166.0	COG3773@1|root,COG3773@2|Bacteria,1RE11@1224|Proteobacteria,2U89A@28211|Alphaproteobacteria,2KGIC@204458|Caulobacterales	204458|Caulobacterales	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
WH3_k127_1513567_1	383381.EH30_02275	1.172e-144	466.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2JZZX@204457|Sphingomonadales	204457|Sphingomonadales	E	overlaps another CDS with the same product name	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WH3_k127_1513567_0	237727.NAP1_01445	3.56e-158	507.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2K05P@204457|Sphingomonadales	204457|Sphingomonadales	E	overlaps another CDS with the same product name	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WH3_k127_1513567_3	1479239.JQMU01000001_gene2398	1.43e-52	195.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,2K5X1@204457|Sphingomonadales	204457|Sphingomonadales	C	Ferredoxin	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
WH3_k127_1513567_2	383381.EH30_02295	1.199e-109	362.0	2E689@1|root,30I1X@2|Bacteria,1NUXE@1224|Proteobacteria,2UR9A@28211|Alphaproteobacteria,2K6GF@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
WH3_k127_1514455_2	1248917.ANFX01000024_gene1124	8.714e-46	175.0	COG3967@1|root,COG3967@2|Bacteria,1QSYJ@1224|Proteobacteria,2UBZS@28211|Alphaproteobacteria,2K48U@204457|Sphingomonadales	204457|Sphingomonadales	M	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
WH3_k127_1514455_0	1248917.ANFX01000024_gene1123	8.711e-191	599.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2TTTU@28211|Alphaproteobacteria,2K2VI@204457|Sphingomonadales	204457|Sphingomonadales	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WH3_k127_1514455_1	1479239.JQMU01000001_gene351	1.577e-163	516.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2K11W@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
WH3_k127_153283_1	1479239.JQMU01000001_gene2796	7.472e-162	514.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U3HG@28211|Alphaproteobacteria,2K0AE@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WH3_k127_153283_0	1088721.NSU_4214	9.355e-177	554.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2K0JS@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WH3_k127_1540709_0	1090319.KE386571_gene1980	5.733e-218	681.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2K03C@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WH3_k127_1540709_1	1479239.JQMU01000001_gene2584	4.094e-160	509.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2TQT1@28211|Alphaproteobacteria,2K1CJ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
WH3_k127_1596168_2	1248917.ANFX01000041_gene1716	8.966e-14	73.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,2K7GT@204457|Sphingomonadales	204457|Sphingomonadales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
WH3_k127_1596168_0	1248917.ANFX01000041_gene1715	1.963e-266	826.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,2TRRQ@28211|Alphaproteobacteria,2K1EZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WH3_k127_1596168_1	1248917.ANFX01000041_gene1714	2.113e-167	530.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K27R@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH3_k127_1596702_5	1248917.ANFX01000029_gene2643	5.317e-22	97.0	COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,2K4K6@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
WH3_k127_1596702_3	1479239.JQMU01000001_gene1873	1.276e-92	307.0	COG5452@1|root,COG5452@2|Bacteria,1N12T@1224|Proteobacteria,2UCES@28211|Alphaproteobacteria,2K6M4@204457|Sphingomonadales	204457|Sphingomonadales	S	Ubiquinol-cytochrome C chaperone	-	-	-	ko:K17662	-	-	-	-	ko00000,ko03029	-	-	-	Ubiq_cyt_C_chap
WH3_k127_1596702_4	1479239.JQMU01000001_gene1874	1.405e-77	263.0	COG2913@1|root,COG2913@2|Bacteria,1RHYM@1224|Proteobacteria,2UBU9@28211|Alphaproteobacteria,2K4H5@204457|Sphingomonadales	204457|Sphingomonadales	J	Small protein A (tmRNA-binding)	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
WH3_k127_1596702_2	1479239.JQMU01000001_gene1875	5.721e-101	334.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,2K0IZ@204457|Sphingomonadales	204457|Sphingomonadales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
WH3_k127_1596702_1	1248917.ANFX01000029_gene2639	2.808e-131	429.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WH3_k127_1596702_0	1479239.JQMU01000001_gene1876	4.33e-143	456.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2K0UP@204457|Sphingomonadales	204457|Sphingomonadales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
WH3_k127_1618687_3	1479239.JQMU01000001_gene2521	3.621e-118	383.0	COG3391@1|root,COG3391@2|Bacteria,1R53R@1224|Proteobacteria,2U1FC@28211|Alphaproteobacteria,2K0VC@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1618687_0	1479239.JQMU01000001_gene2522	3.057e-199	625.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria,2K1HI@204457|Sphingomonadales	204457|Sphingomonadales	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
WH3_k127_1618687_1	1479239.JQMU01000001_gene2523	2.293e-147	469.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TTR3@28211|Alphaproteobacteria,2K2H5@204457|Sphingomonadales	204457|Sphingomonadales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
WH3_k127_1618687_2	1479239.JQMU01000001_gene2524	1.203e-140	449.0	COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,2TT79@28211|Alphaproteobacteria,2K0H1@204457|Sphingomonadales	204457|Sphingomonadales	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
WH3_k127_1618687_4	1479239.JQMU01000001_gene2525	2.162e-78	264.0	COG0864@1|root,COG0864@2|Bacteria,1RDN6@1224|Proteobacteria,2U61K@28211|Alphaproteobacteria,2K4CQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	NikR_C,RHH_1
WH3_k127_1618687_5	1479239.JQMU01000001_gene2526	4.468e-34	137.0	COG3665@1|root,COG3665@2|Bacteria,1N2KR@1224|Proteobacteria,2TSBV@28211|Alphaproteobacteria,2K1Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
WH3_k127_165321_0	1248917.ANFX01000012_gene1781	5.724e-209	662.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,2U2MN@28211|Alphaproteobacteria,2K2I5@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
WH3_k127_165321_1	1479239.JQMU01000001_gene2195	3.549e-120	394.0	2DV5K@1|root,33U5R@2|Bacteria,1MYQC@1224|Proteobacteria,2UB5F@28211|Alphaproteobacteria,2K8VS@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_165321_2	1479239.JQMU01000001_gene2196	9.29e-55	197.0	COG2831@1|root,COG2831@2|Bacteria,1R6KX@1224|Proteobacteria,2TUEN@28211|Alphaproteobacteria,2K29V@204457|Sphingomonadales	204457|Sphingomonadales	U	COG2831 Hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
WH3_k127_1661161_3	1479239.JQMU01000001_gene2718	5.776e-21	96.0	COG0822@1|root,COG0822@2|Bacteria,1RDGB@1224|Proteobacteria,2U74A@28211|Alphaproteobacteria,2K54B@204457|Sphingomonadales	204457|Sphingomonadales	C	NifU homolog involved in Fe-S cluster formation	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
WH3_k127_1661161_2	1479239.JQMU01000001_gene2717	3.184e-79	267.0	COG1286@1|root,COG1286@2|Bacteria,1REF7@1224|Proteobacteria,2VA4D@28211|Alphaproteobacteria,2K52S@204457|Sphingomonadales	204457|Sphingomonadales	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
WH3_k127_1661161_0	1248917.ANFX01000008_gene248	7.801e-266	822.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,2K1F3@204457|Sphingomonadales	204457|Sphingomonadales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
WH3_k127_1661161_1	1479239.JQMU01000001_gene2715	4.638e-168	538.0	COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2TU16@28211|Alphaproteobacteria,2K0ET@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3376)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3376,Patatin
WH3_k127_1675340_1	1479239.JQMU01000001_gene2452	2.083e-127	409.0	COG2885@1|root,COG2885@2|Bacteria,1R5IS@1224|Proteobacteria,2U2V8@28211|Alphaproteobacteria,2K1H8@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WH3_k127_1675340_2	383381.EH30_02640	1.35e-121	392.0	COG0665@1|root,COG0665@2|Bacteria,1N2VH@1224|Proteobacteria,2UC03@28211|Alphaproteobacteria,2K4B8@204457|Sphingomonadales	204457|Sphingomonadales	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1675340_0	1248917.ANFX01000037_gene2010	0.0	1216.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,2K1TK@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
WH3_k127_1682505_1	1122970.AUHC01000001_gene839	4e-81	271.0	COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,2U11H@28211|Alphaproteobacteria,2K2RQ@204457|Sphingomonadales	204457|Sphingomonadales	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
WH3_k127_1682505_0	1122970.AUHC01000002_gene1449	2.056e-154	494.0	COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,2TUDJ@28211|Alphaproteobacteria,2JZUY@204457|Sphingomonadales	204457|Sphingomonadales	I	3-phytase	phy	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
WH3_k127_1708254_2	1479239.JQMU01000001_gene2346	7.129e-112	364.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2TSVG@28211|Alphaproteobacteria,2K0AG@204457|Sphingomonadales	204457|Sphingomonadales	E	tRNA synthetase, class II	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
WH3_k127_1708254_4	1479239.JQMU01000001_gene2347	1.03e-64	224.0	COG0251@1|root,COG0251@2|Bacteria,1REJQ@1224|Proteobacteria,2U70D@28211|Alphaproteobacteria,2K5HA@204457|Sphingomonadales	204457|Sphingomonadales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WH3_k127_1708254_1	1479239.JQMU01000001_gene2348	5.943e-169	538.0	COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,2U4WU@28211|Alphaproteobacteria,2KCR3@204457|Sphingomonadales	204457|Sphingomonadales	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WH3_k127_1708254_0	1248917.ANFX01000022_gene684	4.223e-273	850.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria,2K0T7@204457|Sphingomonadales	204457|Sphingomonadales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WH3_k127_1708254_3	1479239.JQMU01000001_gene2350	5.752e-97	319.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2TS2U@28211|Alphaproteobacteria,2KA2Q@204457|Sphingomonadales	204457|Sphingomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WH3_k127_1708254_5	317655.Sala_0407	1.047e-19	87.0	COG0309@1|root,COG0309@2|Bacteria,1RDJ4@1224|Proteobacteria,2U7HE@28211|Alphaproteobacteria,2K4T1@204457|Sphingomonadales	204457|Sphingomonadales	O	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_2
WH3_k127_1726980_0	1479239.JQMU01000001_gene2272	1.977e-202	631.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,2K06N@204457|Sphingomonadales	204457|Sphingomonadales	E	highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WH3_k127_1726980_2	1479239.JQMU01000001_gene2273	3.944e-59	209.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,2K4IQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
WH3_k127_1726980_1	517722.AEUE01000004_gene773	2.043e-64	223.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2K2G3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
WH3_k127_1728198_4	1479239.JQMU01000001_gene2496	9.374e-10	59.0	COG1977@1|root,COG1977@2|Bacteria,1NKJE@1224|Proteobacteria,2UKXA@28211|Alphaproteobacteria,2K7QU@204457|Sphingomonadales	204457|Sphingomonadales	H	Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WH3_k127_1728198_0	1479239.JQMU01000001_gene2495	7.021e-197	617.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,2K041@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
WH3_k127_1728198_3	517722.AEUE01000007_gene424	1.079e-13	76.0	2AMFW@1|root,31CBD@2|Bacteria,1NPT4@1224|Proteobacteria,2UMCJ@28211|Alphaproteobacteria,2K7Z7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1728198_2	1479239.JQMU01000001_gene2493	3.484e-67	234.0	COG1539@1|root,COG1539@2|Bacteria,1RKNS@1224|Proteobacteria,2UAD6@28211|Alphaproteobacteria,2K58X@204457|Sphingomonadales	204457|Sphingomonadales	H	dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
WH3_k127_1728198_1	1479239.JQMU01000001_gene2492	2.318e-102	334.0	COG1092@1|root,COG1092@2|Bacteria,1QSD4@1224|Proteobacteria,2TUFT@28211|Alphaproteobacteria,2K037@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WH3_k127_1738504_0	1248917.ANFX01000014_gene1332	5e-324	996.0	COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,2TZ9G@28211|Alphaproteobacteria,2K0JV@204457|Sphingomonadales	204457|Sphingomonadales	O	Alkyl hydroperoxide reductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
WH3_k127_1738504_1	383381.EH30_11390	6.217e-92	303.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,2K0B7@204457|Sphingomonadales	204457|Sphingomonadales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
WH3_k127_1782341_0	1248917.ANFX01000030_gene501	3.081e-133	431.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2TU5Q@28211|Alphaproteobacteria,2K193@204457|Sphingomonadales	204457|Sphingomonadales	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
WH3_k127_1782341_2	1007104.SUS17_1712	8.272e-94	333.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K0BV@204457|Sphingomonadales	204457|Sphingomonadales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
WH3_k127_1782341_3	1479239.JQMU01000001_gene945	1.994e-43	160.0	COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,2UFME@28211|Alphaproteobacteria,2K6KA@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1272)	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
WH3_k127_1782341_1	1479239.JQMU01000001_gene944	1.196e-124	401.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JZV4@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH3_k127_1785764_4	1479239.JQMU01000001_gene1024	1.349e-93	310.0	2F69V@1|root,33YTJ@2|Bacteria,1MYST@1224|Proteobacteria,2UA2M@28211|Alphaproteobacteria,2K4MC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1785764_6	1479239.JQMU01000001_gene1025	3.519e-48	173.0	2E9WT@1|root,33CDQ@2|Bacteria,1NDWW@1224|Proteobacteria,2UH4W@28211|Alphaproteobacteria,2K6WY@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
WH3_k127_1785764_0	1248917.ANFX01000050_gene620	0.0	1239.0	COG3279@1|root,COG4251@1|root,COG3279@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2TWHG@28211|Alphaproteobacteria,2KEPG@204457|Sphingomonadales	204457|Sphingomonadales	T	Phytochrome region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c_2,HWE_HK,HisKA_2,PAS_2,PHY,Response_reg
WH3_k127_1785764_2	1248917.ANFX01000050_gene621	9.516e-131	425.0	COG1482@1|root,COG1482@2|Bacteria,1P6JR@1224|Proteobacteria,2U30V@28211|Alphaproteobacteria,2K0Y1@204457|Sphingomonadales	204457|Sphingomonadales	G	isomerase	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	-
WH3_k127_1785764_1	1248917.ANFX01000050_gene622	6.771e-182	573.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2TT0R@28211|Alphaproteobacteria,2K066@204457|Sphingomonadales	204457|Sphingomonadales	M	Mannose-1-phosphate guanylyltransferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WH3_k127_1785764_3	1479239.JQMU01000001_gene1028	5.041e-107	351.0	COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2UJ8K@28211|Alphaproteobacteria,2K536@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WH3_k127_1804904_0	383381.EH30_02485	4.724e-105	351.0	COG0457@1|root,COG0457@2|Bacteria,1R530@1224|Proteobacteria,2TWPW@28211|Alphaproteobacteria,2K34N@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1804904_2	383381.EH30_02480	1.954e-79	274.0	29WZ9@1|root,30IMG@2|Bacteria,1MXG3@1224|Proteobacteria,2U1X3@28211|Alphaproteobacteria,2K0FH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
WH3_k127_1804904_1	383381.EH30_02475	2.14e-101	335.0	2AB1F@1|root,310F3@2|Bacteria,1R7ZR@1224|Proteobacteria,2TTWQ@28211|Alphaproteobacteria,2K0R6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
WH3_k127_1804904_3	1479239.JQMU01000001_gene2432	1.264e-27	112.0	29CM7@1|root,2ZZJH@2|Bacteria,1P7WF@1224|Proteobacteria,2UWCP@28211|Alphaproteobacteria,2KBP8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_1857970_1	1479239.JQMU01000001_gene2692	1.797e-88	293.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2K0XS@204457|Sphingomonadales	204457|Sphingomonadales	S	Von Willebrand factor A	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
WH3_k127_1857970_0	1248917.ANFX01000008_gene280	8.276e-252	782.0	COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,2TTNX@28211|Alphaproteobacteria,2K1FW@204457|Sphingomonadales	204457|Sphingomonadales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
WH3_k127_1857970_2	1122612.AUBA01000015_gene925	3.439e-18	84.0	COG3791@1|root,COG3791@2|Bacteria,1N01M@1224|Proteobacteria,2UGEY@28211|Alphaproteobacteria,2KD96@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
WH3_k127_194677_2	1479239.JQMU01000001_gene2339	4.598e-120	387.0	2CF7S@1|root,32S1E@2|Bacteria,1R918@1224|Proteobacteria,2U3VN@28211|Alphaproteobacteria,2K2C5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_194677_1	1248917.ANFX01000022_gene668	9.618e-173	544.0	COG0825@1|root,COG0825@2|Bacteria,1NTQA@1224|Proteobacteria,2UQ1V@28211|Alphaproteobacteria,2K8XT@204457|Sphingomonadales	204457|Sphingomonadales	I	Malonate decarboxylase gamma subunit (MdcE)	-	-	-	-	-	-	-	-	-	-	-	-	ACCA
WH3_k127_194677_0	1248917.ANFX01000022_gene667	1.138e-190	596.0	COG1028@1|root,COG1028@2|Bacteria,1R6F3@1224|Proteobacteria,2U1Z9@28211|Alphaproteobacteria,2K0Y6@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WH3_k127_1989786_0	1479239.JQMU01000001_gene908	4.788e-296	911.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,2K0JK@204457|Sphingomonadales	204457|Sphingomonadales	E	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
WH3_k127_2032808_3	383381.EH30_05960	2.12e-28	114.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,2K09I@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WH3_k127_2032808_2	1044.EH31_01770	5.704e-55	198.0	COG2340@1|root,COG2340@2|Bacteria,1N9SZ@1224|Proteobacteria,2UTM1@28211|Alphaproteobacteria,2K4A7@204457|Sphingomonadales	204457|Sphingomonadales	S	SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.	-	-	-	-	-	-	-	-	-	-	-	-	CAP
WH3_k127_2032808_1	1479239.JQMU01000001_gene2705	4.167e-120	388.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria,2K1NS@204457|Sphingomonadales	204457|Sphingomonadales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WH3_k127_2032808_0	383381.EH30_05970	5.567e-139	445.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,2K0PW@204457|Sphingomonadales	204457|Sphingomonadales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
WH3_k127_2032808_4	1479239.JQMU01000001_gene2707	6.245e-14	77.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria,2K03N@204457|Sphingomonadales	204457|Sphingomonadales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
WH3_k127_2052148_7	1248917.ANFX01000016_gene2486	3.016e-28	118.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2TTX5@28211|Alphaproteobacteria,2K0AH@204457|Sphingomonadales	204457|Sphingomonadales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
WH3_k127_2052148_1	1248917.ANFX01000016_gene2487	0.0	1027.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,2U0DP@28211|Alphaproteobacteria,2K0HA@204457|Sphingomonadales	204457|Sphingomonadales	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WH3_k127_2052148_2	1248917.ANFX01000016_gene2488	1.593e-315	970.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,2K1CG@204457|Sphingomonadales	204457|Sphingomonadales	G	Alpha-amylase domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
WH3_k127_2052148_4	1122970.AUHC01000004_gene2245	3.308e-192	605.0	COG1609@1|root,COG1609@2|Bacteria,1MW7E@1224|Proteobacteria,2U1NM@28211|Alphaproteobacteria,2KCYY@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
WH3_k127_2052148_3	1248917.ANFX01000016_gene2490	5.111e-295	912.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2TTKE@28211|Alphaproteobacteria,2JZZ7@204457|Sphingomonadales	204457|Sphingomonadales	E	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
WH3_k127_2052148_0	1122970.AUHC01000004_gene2243	0.0	1594.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWTT@1224|Proteobacteria,2TURM@28211|Alphaproteobacteria,2K1TV@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
WH3_k127_2052148_6	1122970.AUHC01000004_gene2242	2.547e-96	321.0	COG0665@1|root,COG0665@2|Bacteria,1N2VH@1224|Proteobacteria,2VGVH@28211|Alphaproteobacteria,2KE6H@204457|Sphingomonadales	204457|Sphingomonadales	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2052148_5	1248917.ANFX01000016_gene2493	7.446e-188	591.0	COG0665@1|root,COG0665@2|Bacteria,1MU40@1224|Proteobacteria,2TTKE@28211|Alphaproteobacteria,2JZZ7@204457|Sphingomonadales	204457|Sphingomonadales	E	Tryptophan halogenase	-	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
WH3_k127_2060816_4	1479239.JQMU01000001_gene1675	4.763e-18	83.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2K4E7@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WH3_k127_2060816_2	1248917.ANFX01000029_gene2677	2.755e-112	365.0	2C0PG@1|root,330E3@2|Bacteria,1RA6M@1224|Proteobacteria,2U5UJ@28211|Alphaproteobacteria,2K3P1@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
WH3_k127_2060816_1	1479239.JQMU01000001_gene1673	5.169e-201	628.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2TQZX@28211|Alphaproteobacteria,2K24N@204457|Sphingomonadales	204457|Sphingomonadales	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WH3_k127_2060816_0	1122970.AUHC01000013_gene1098	3.857e-276	854.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,2K03M@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WH3_k127_2066322_0	1479239.JQMU01000001_gene386	1.255e-276	856.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U1C8@28211|Alphaproteobacteria,2K3AZ@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_2066322_1	1248917.ANFX01000040_gene771	5.61e-132	422.0	COG1414@1|root,COG1414@2|Bacteria,1QYTM@1224|Proteobacteria,2U04P@28211|Alphaproteobacteria,2K2VC@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
WH3_k127_2071436_1	1479239.JQMU01000001_gene1714	2.746e-104	342.0	COG1291@1|root,COG1291@2|Bacteria,1N0TR@1224|Proteobacteria,2UBP6@28211|Alphaproteobacteria,2K5AE@204457|Sphingomonadales	204457|Sphingomonadales	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
WH3_k127_2071436_2	1479239.JQMU01000001_gene1715	7.574e-59	213.0	2A03Q@1|root,30N68@2|Bacteria,1NNTD@1224|Proteobacteria,2UNFX@28211|Alphaproteobacteria,2KB36@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2071436_0	1479239.JQMU01000001_gene1716	4.372e-188	593.0	COG2199@1|root,COG2199@2|Bacteria,1N1BS@1224|Proteobacteria,2UQ0F@28211|Alphaproteobacteria,2KEKT@204457|Sphingomonadales	204457|Sphingomonadales	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
WH3_k127_2080570_1	1479239.JQMU01000001_gene2754	2.148e-174	551.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,2K1YJ@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
WH3_k127_2080570_2	1112212.JH584235_gene553	9.047e-155	502.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH3_k127_2080570_0	1479239.JQMU01000001_gene2752	0.0	1045.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,2K01N@204457|Sphingomonadales	204457|Sphingomonadales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
WH3_k127_2082403_5	1479239.JQMU01000001_gene1585	7.297e-49	176.0	COG2128@1|root,COG2128@2|Bacteria,1N56H@1224|Proteobacteria,2UABU@28211|Alphaproteobacteria,2K41Y@204457|Sphingomonadales	204457|Sphingomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WH3_k127_2082403_4	1122970.AUHC01000011_gene2689	7.604e-65	230.0	COG3631@1|root,COG3631@2|Bacteria,1PUKQ@1224|Proteobacteria,2V678@28211|Alphaproteobacteria,2KABR@204457|Sphingomonadales	204457|Sphingomonadales	S	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WH3_k127_2082403_3	1248917.ANFX01000019_gene2343	3.096e-98	323.0	COG5517@1|root,COG5517@2|Bacteria,1RAFN@1224|Proteobacteria,2VDNY@28211|Alphaproteobacteria,2K8AH@204457|Sphingomonadales	204457|Sphingomonadales	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
WH3_k127_2082403_0	1248917.ANFX01000019_gene2341	2.809e-257	798.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2K2HH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_2082403_2	1479239.JQMU01000001_gene1580	2.165e-111	366.0	COG2128@1|root,COG2128@2|Bacteria,1RI8R@1224|Proteobacteria,2UJBV@28211|Alphaproteobacteria,2K84A@204457|Sphingomonadales	204457|Sphingomonadales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WH3_k127_2082403_1	1248917.ANFX01000019_gene2339	5.409e-165	519.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2K2HH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_2093384_6	1479239.JQMU01000001_gene2783	1.869e-87	292.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,2K0KV@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
WH3_k127_2093384_0	1479239.JQMU01000001_gene2784	1.568e-285	885.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,2K00K@204457|Sphingomonadales	204457|Sphingomonadales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
WH3_k127_2093384_3	1479239.JQMU01000001_gene2785	1.646e-124	411.0	COG3698@1|root,COG3698@2|Bacteria,1NH9S@1224|Proteobacteria,2TT5B@28211|Alphaproteobacteria,2K46M@204457|Sphingomonadales	204457|Sphingomonadales	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
WH3_k127_2093384_4	1248917.ANFX01000010_gene208	2.183e-121	391.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,2K28N@204457|Sphingomonadales	204457|Sphingomonadales	EH	with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WH3_k127_2093384_1	1248917.ANFX01000010_gene207	1.85e-183	580.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,2K11A@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
WH3_k127_2093384_2	1248917.ANFX01000010_gene206	1.562e-137	443.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,2K0PS@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
WH3_k127_2093384_7	1479239.JQMU01000001_gene2789	5.541e-74	252.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,2K4GG@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
WH3_k127_2093384_5	1479239.JQMU01000001_gene2790	2.52e-109	362.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,2K1RP@204457|Sphingomonadales	204457|Sphingomonadales	H	molybdopterin biosynthesis	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WH3_k127_2096525_1	1248760.ANFZ01000009_gene1365	7.799e-46	171.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2UBS6@28211|Alphaproteobacteria,2KD1J@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_2096525_3	1248760.ANFZ01000009_gene1364	4.86e-29	126.0	COG5662@1|root,COG5662@2|Bacteria,1N1PB@1224|Proteobacteria,2VGMS@28211|Alphaproteobacteria,2KE4R@204457|Sphingomonadales	204457|Sphingomonadales	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2096525_0	1248760.ANFZ01000009_gene1363	1.264e-135	440.0	COG3203@1|root,COG3203@2|Bacteria,1PQIR@1224|Proteobacteria,2V2XM@28211|Alphaproteobacteria,2K94V@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
WH3_k127_2096525_2	1248760.ANFZ01000009_gene1362	2.03e-34	139.0	COG1073@1|root,COG1073@2|Bacteria,1QUQB@1224|Proteobacteria,2UC51@28211|Alphaproteobacteria,2K5XH@204457|Sphingomonadales	204457|Sphingomonadales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2098828_1	1479239.JQMU01000001_gene2800	3.695e-88	295.0	COG1196@1|root,COG1196@2|Bacteria,1MVEP@1224|Proteobacteria,2TR50@28211|Alphaproteobacteria,2K0N2@204457|Sphingomonadales	204457|Sphingomonadales	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2098828_2	1479239.JQMU01000001_gene2799	1.846e-45	170.0	2AFMU@1|root,315P6@2|Bacteria,1NDJZ@1224|Proteobacteria,2UHNJ@28211|Alphaproteobacteria,2K65G@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2098828_0	1479239.JQMU01000001_gene2798	4.615e-117	389.0	2AKKZ@1|root,31BDD@2|Bacteria,1NNE3@1224|Proteobacteria,2UMPR@28211|Alphaproteobacteria,2K72H@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2098828_3	1479239.JQMU01000001_gene2797	6.151e-14	72.0	COG0645@1|root,COG0645@2|Bacteria,1NU12@1224|Proteobacteria,2UQFM@28211|Alphaproteobacteria,2KDKW@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2100417_1	1479239.JQMU01000001_gene1419	3.914e-83	279.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,2K0RQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WH3_k127_2100417_0	1479239.JQMU01000001_gene1420	1.436e-158	501.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,2K02Z@204457|Sphingomonadales	204457|Sphingomonadales	D	Chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WH3_k127_2100417_2	1248917.ANFX01000005_gene127	2.991e-36	137.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,2K4N2@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WH3_k127_2116080_0	1479239.JQMU01000001_gene550	0.0	1000.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,2K0VM@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WH3_k127_2124220_4	1122970.AUHC01000015_gene2555	1.408e-95	314.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,2K0B7@204457|Sphingomonadales	204457|Sphingomonadales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
WH3_k127_2124220_5	1479239.JQMU01000001_gene987	4.628e-90	304.0	COG0500@1|root,COG0500@2|Bacteria,1REJ2@1224|Proteobacteria,2U7T5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WH3_k127_2124220_2	1122970.AUHC01000015_gene2557	5.399e-162	513.0	COG0330@1|root,COG0330@2|Bacteria,1P8ZI@1224|Proteobacteria,2TTBE@28211|Alphaproteobacteria,2JZUP@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WH3_k127_2124220_7	1248917.ANFX01000014_gene1321	1.205e-24	105.0	COG4877@1|root,COG4877@2|Bacteria,1NJMT@1224|Proteobacteria,2UK5B@28211|Alphaproteobacteria,2K6XY@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicB
WH3_k127_2124220_6	383381.EH30_11360	7.613e-59	210.0	COG1719@1|root,COG1719@2|Bacteria,1REDE@1224|Proteobacteria,2UA9M@28211|Alphaproteobacteria,2K549@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacteriochlorophyll 4-vinyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2124220_0	1479239.JQMU01000001_gene996	0.0	1031.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TUPK@28211|Alphaproteobacteria,2KD0S@204457|Sphingomonadales	204457|Sphingomonadales	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
WH3_k127_2124220_3	1479239.JQMU01000001_gene997	8.188e-116	375.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TTXE@28211|Alphaproteobacteria,2JZZH@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH3_k127_2124220_1	1248917.ANFX01000014_gene1316	1.457e-236	733.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2TRCC@28211|Alphaproteobacteria,2K0BD@204457|Sphingomonadales	204457|Sphingomonadales	E	4-hydroxyphenylpyruvate dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
WH3_k127_2148730_1	1479239.JQMU01000001_gene226	6.477e-68	235.0	COG0711@1|root,COG0711@2|Bacteria,1N0P5@1224|Proteobacteria,2U5DD@28211|Alphaproteobacteria,2K57Z@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF_2	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
WH3_k127_2148730_4	1449076.JOOE01000002_gene1501	3.266e-38	149.0	COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,2K5D0@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF_1	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
WH3_k127_2148730_5	237727.NAP1_06785	7.973e-34	131.0	COG0636@1|root,COG0636@2|Bacteria,1MZBU@1224|Proteobacteria,2UFPN@28211|Alphaproteobacteria,2K61N@204457|Sphingomonadales	204457|Sphingomonadales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WH3_k127_2148730_0	237727.NAP1_06790	7.392e-150	479.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,2K17B@204457|Sphingomonadales	204457|Sphingomonadales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WH3_k127_2148730_3	237727.NAP1_06795	1.409e-50	182.0	COG5336@1|root,COG5336@2|Bacteria,1N2ME@1224|Proteobacteria,2UCBR@28211|Alphaproteobacteria,2K62W@204457|Sphingomonadales	204457|Sphingomonadales	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
WH3_k127_2148730_2	1479239.JQMU01000001_gene231	1.557e-65	225.0	COG3784@1|root,COG3784@2|Bacteria,1Q09W@1224|Proteobacteria,2UCIH@28211|Alphaproteobacteria,2K5RZ@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
WH3_k127_2148770_0	1248917.ANFX01000013_gene1448	3.588e-240	749.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TUBY@28211|Alphaproteobacteria,2K1FB@204457|Sphingomonadales	204457|Sphingomonadales	EH	component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
WH3_k127_2148770_1	1479239.JQMU01000001_gene1164	5.728e-161	509.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria,2JZYW@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
WH3_k127_2183804_0	1044.EH31_06485	4.433e-279	873.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,2TW2S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	amine dehydrogenase activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,Cadherin_3,FecR,PPC,Peptidase_M10_C
WH3_k127_2183804_1	1479239.JQMU01000001_gene1551	2.078e-204	648.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,2K0NT@204457|Sphingomonadales	204457|Sphingomonadales	MU	RND efflux system, outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_2183804_2	1479239.JQMU01000001_gene1550	2.775e-150	487.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2U139@28211|Alphaproteobacteria,2K18J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
WH3_k127_2198386_0	1479239.JQMU01000001_gene2058	5e-324	996.0	COG3451@1|root,COG3451@2|Bacteria,1MXH0@1224|Proteobacteria,2TR1U@28211|Alphaproteobacteria,2K13S@204457|Sphingomonadales	204457|Sphingomonadales	U	type IV secretion system	-	-	-	ko:K03199	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	CagE_TrbE_VirB
WH3_k127_2198386_3	1122970.AUHC01000004_gene2299	2.624e-54	190.0	COG3702@1|root,COG3702@2|Bacteria,1N1YI@1224|Proteobacteria,2UDDW@28211|Alphaproteobacteria,2K6H2@204457|Sphingomonadales	204457|Sphingomonadales	U	Type IV secretory pathway	-	-	-	ko:K03198	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	VirB3
WH3_k127_2198386_5	1248917.ANFX01000016_gene2429	3.447e-44	167.0	COG3838@1|root,COG3838@2|Bacteria,1N55M@1224|Proteobacteria,2UD7V@28211|Alphaproteobacteria,2K6KF@204457|Sphingomonadales	204457|Sphingomonadales	U	Type IV secretory pathway, VirB2	-	-	-	ko:K03197	ko03070,ko05134,map03070,map05134	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	TrbC
WH3_k127_2198386_2	1479239.JQMU01000001_gene2055	2.686e-109	356.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2U5GT@28211|Alphaproteobacteria,2KD6E@204457|Sphingomonadales	204457|Sphingomonadales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WH3_k127_2198386_4	1479239.JQMU01000001_gene2054	6.016e-51	184.0	COG0457@1|root,COG0457@2|Bacteria,1NPY1@1224|Proteobacteria,2UKIN@28211|Alphaproteobacteria,2KDRW@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
WH3_k127_2198386_1	1122970.AUHC01000004_gene2295	3.988e-175	557.0	COG2182@1|root,COG2182@2|Bacteria,1MU3H@1224|Proteobacteria,2U0ZI@28211|Alphaproteobacteria,2K10P@204457|Sphingomonadales	204457|Sphingomonadales	G	Extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2200265_1	1248917.ANFX01000029_gene2654	4.358e-64	220.0	COG1670@1|root,COG1670@2|Bacteria,1RK5M@1224|Proteobacteria,2UBIE@28211|Alphaproteobacteria,2K4T5@204457|Sphingomonadales	204457|Sphingomonadales	J	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH3_k127_2200265_0	1248917.ANFX01000029_gene2655	5.988e-213	666.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2TS9C@28211|Alphaproteobacteria,2K0UV@204457|Sphingomonadales	204457|Sphingomonadales	E	PFAM Aminotransferase class I and II	-	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_2254115_0	1479239.JQMU01000001_gene287	0.0	1088.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2K07V@204457|Sphingomonadales	204457|Sphingomonadales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WH3_k127_2256615_0	1248917.ANFX01000041_gene1730	1.086e-311	957.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,2K19P@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
WH3_k127_2257486_7	1248917.ANFX01000008_gene266	4.231e-30	120.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,2K09I@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WH3_k127_2257486_3	1479239.JQMU01000001_gene2703	4.903e-156	496.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,2K1R3@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	xerC_2	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WH3_k127_2257486_5	1479239.JQMU01000001_gene2702	3.258e-118	382.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2U6ZF@28211|Alphaproteobacteria,2K1Q0@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WH3_k127_2257486_2	1479239.JQMU01000001_gene2701	5.183e-192	604.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,2K0JQ@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
WH3_k127_2257486_6	1122970.AUHC01000001_gene483	2.677e-47	183.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria,2K62R@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
WH3_k127_2257486_4	1479239.JQMU01000001_gene2699	6.261e-141	453.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,2K0AW@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WH3_k127_2257486_1	1479239.JQMU01000001_gene2698	3.28e-201	632.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,2TW21@28211|Alphaproteobacteria,2KE92@204457|Sphingomonadales	204457|Sphingomonadales	M	LppC putative lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
WH3_k127_2257486_0	1479239.JQMU01000001_gene2697	7.597e-279	860.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,2K2GE@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WH3_k127_2277088_1	1479239.JQMU01000001_gene1972	1.45e-170	541.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2TRIC@28211|Alphaproteobacteria,2K1QQ@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WH3_k127_2277088_2	1479239.JQMU01000001_gene1973	1.84e-128	429.0	2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,2TQWW@28211|Alphaproteobacteria,2JZXR@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
WH3_k127_2277088_0	1479239.JQMU01000001_gene1974	4.54e-309	950.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,2TUN9@28211|Alphaproteobacteria,2K091@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
WH3_k127_2294943_1	1248917.ANFX01000019_gene2356	8.27e-153	484.0	COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2U471@28211|Alphaproteobacteria,2K3WA@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.51	ko:K05296	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	-	R01836,R01838,R02352,R02353,R03406,R03407,R09956,R09957	RC00127,RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WH3_k127_2294943_0	1479239.JQMU01000001_gene1598	1.757e-236	736.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2TSXW@28211|Alphaproteobacteria,2K9W9@204457|Sphingomonadales	204457|Sphingomonadales	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_2294943_2	1479239.JQMU01000001_gene1599	3.027e-142	454.0	COG1028@1|root,COG1028@2|Bacteria,1RGQG@1224|Proteobacteria,2VFFQ@28211|Alphaproteobacteria,2K4ZF@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_2294943_3	1479239.JQMU01000001_gene1600	6.128e-133	424.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2TTDK@28211|Alphaproteobacteria,2K5H6@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N_3
WH3_k127_2297377_5	1248917.ANFX01000037_gene2025	2.886e-38	144.0	COG4427@1|root,COG4427@2|Bacteria,1R4EV@1224|Proteobacteria,2TRVP@28211|Alphaproteobacteria,2K05T@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
WH3_k127_2297377_3	1479239.JQMU01000001_gene2462	1.163e-125	409.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2TT0H@28211|Alphaproteobacteria,2K1K3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
WH3_k127_2297377_1	1248917.ANFX01000037_gene2023	6.64e-248	770.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,2K0A0@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
WH3_k127_2297377_4	1479239.JQMU01000001_gene2460	4.595e-76	262.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2UBQA@28211|Alphaproteobacteria,2K4I2@204457|Sphingomonadales	204457|Sphingomonadales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WH3_k127_2297377_2	1479239.JQMU01000001_gene2459	3.986e-152	484.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2TTI6@28211|Alphaproteobacteria,2K0EU@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WH3_k127_2297377_0	983920.Y88_3598	0.0	1091.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2TR9G@28211|Alphaproteobacteria,2K0XA@204457|Sphingomonadales	204457|Sphingomonadales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
WH3_k127_2314629_0	1479239.JQMU01000001_gene1465	0.0	1140.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria,2K12J@204457|Sphingomonadales	204457|Sphingomonadales	I	synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
WH3_k127_2314629_1	1088721.NSU_0146	7.121e-81	271.0	28J1E@1|root,2Z8YB@2|Bacteria,1MWFX@1224|Proteobacteria,2TVQI@28211|Alphaproteobacteria,2K4EV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2453211_0	1479239.JQMU01000001_gene1621	0.0	1239.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
WH3_k127_2453211_1	1479239.JQMU01000001_gene919	1.483e-178	565.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2U43E@28211|Alphaproteobacteria,2K3B1@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_2453211_2	1479239.JQMU01000001_gene918	9.851e-143	456.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2TRYX@28211|Alphaproteobacteria,2K204@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
WH3_k127_2453211_3	1122970.AUHC01000002_gene1445	2.541e-135	435.0	COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,2TRCG@28211|Alphaproteobacteria,2K0ND@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_2464175_0	383381.EH30_05820	1.975e-85	290.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,2K09E@204457|Sphingomonadales	204457|Sphingomonadales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WH3_k127_2464175_1	1479239.JQMU01000001_gene2675	5.5e-60	218.0	COG0500@1|root,COG0500@2|Bacteria,1QUNM@1224|Proteobacteria,2TW20@28211|Alphaproteobacteria,2KE91@204457|Sphingomonadales	204457|Sphingomonadales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WH3_k127_2500926_1	1479239.JQMU01000001_gene2246	7.573e-118	381.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria,2K0NG@204457|Sphingomonadales	204457|Sphingomonadales	I	Lysophospholipase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
WH3_k127_2500926_0	1479239.JQMU01000001_gene2247	5.297e-200	627.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2JZYS@204457|Sphingomonadales	204457|Sphingomonadales	E	Oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
WH3_k127_2523609_0	1479239.JQMU01000001_gene2854	1.752e-247	767.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TRP2@28211|Alphaproteobacteria,2K0DK@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_2523609_1	1122970.AUHC01000001_gene620	2.528e-111	364.0	COG5653@1|root,COG5653@2|Bacteria,1RDJC@1224|Proteobacteria,2U32H@28211|Alphaproteobacteria,2K270@204457|Sphingomonadales	204457|Sphingomonadales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WH3_k127_2523609_5	1479239.JQMU01000001_gene2855	1.23e-42	158.0	COG5653@1|root,COG5653@2|Bacteria,1RDJC@1224|Proteobacteria,2U32H@28211|Alphaproteobacteria,2K270@204457|Sphingomonadales	204457|Sphingomonadales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WH3_k127_2523609_3	1479239.JQMU01000001_gene2856	1.028e-49	178.0	COG0236@1|root,COG0236@2|Bacteria,1N83X@1224|Proteobacteria,2UFBF@28211|Alphaproteobacteria,2K6WR@204457|Sphingomonadales	204457|Sphingomonadales	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
WH3_k127_2523609_2	1479239.JQMU01000001_gene2857	5.632e-104	341.0	COG2267@1|root,COG2267@2|Bacteria,1RJMW@1224|Proteobacteria,2UB7N@28211|Alphaproteobacteria,2K5KA@204457|Sphingomonadales	204457|Sphingomonadales	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_2523609_4	1479239.JQMU01000001_gene2858	3.451e-44	162.0	COG1073@1|root,COG1073@2|Bacteria,1R61B@1224|Proteobacteria,2U45E@28211|Alphaproteobacteria,2K10H@204457|Sphingomonadales	204457|Sphingomonadales	S	TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
WH3_k127_2563518_0	1479239.JQMU01000001_gene182	1.715e-286	881.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2JZXP@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WH3_k127_2563518_2	1479239.JQMU01000001_gene183	8.179e-203	636.0	COG0604@1|root,COG0604@2|Bacteria,1QUNT@1224|Proteobacteria,2TW28@28211|Alphaproteobacteria,2K36M@204457|Sphingomonadales	204457|Sphingomonadales	C	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
WH3_k127_2563518_1	1248917.ANFX01000030_gene509	1.468e-230	716.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,2K052@204457|Sphingomonadales	204457|Sphingomonadales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WH3_k127_2563518_4	1479239.JQMU01000001_gene186	9.685e-150	479.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,2K1MK@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH3_k127_2563518_3	1248917.ANFX01000030_gene506	1.774e-157	502.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,2K15H@204457|Sphingomonadales	204457|Sphingomonadales	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WH3_k127_2563518_5	1479239.JQMU01000001_gene188	1.287e-142	453.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U0U5@28211|Alphaproteobacteria,2K08M@204457|Sphingomonadales	204457|Sphingomonadales	V	proteins, homologs of microcin C7 resistance protein MccF	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
WH3_k127_2586045_1	1248917.ANFX01000019_gene2304	8.173e-41	151.0	COG0236@1|root,COG0236@2|Bacteria,1NHQD@1224|Proteobacteria,2UGSG@28211|Alphaproteobacteria,2K5YB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
WH3_k127_2586045_0	1479239.JQMU01000001_gene1290	1.198e-253	784.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQYP@28211|Alphaproteobacteria,2K0V8@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0156 7-keto-8-aminopelargonate synthetase and related enzymes	-	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_2624294_0	383381.EH30_12425	1.537e-269	835.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2K0FF@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the GMC oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
WH3_k127_2624298_3	1248917.ANFX01000021_gene1640	6.681e-23	98.0	COG3576@1|root,COG3576@2|Bacteria,1R8RC@1224|Proteobacteria,2TUXH@28211|Alphaproteobacteria,2K323@204457|Sphingomonadales	204457|Sphingomonadales	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
WH3_k127_2624298_2	1479239.JQMU01000001_gene1317	2.238e-59	206.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria,2K4EF@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
WH3_k127_2624298_1	1248917.ANFX01000021_gene1638	7.359e-268	832.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,2K0PX@204457|Sphingomonadales	204457|Sphingomonadales	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
WH3_k127_2624298_0	1479239.JQMU01000001_gene1315	0.0	998.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2K0FF@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the GMC oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
WH3_k127_2682301_2	1479239.JQMU01000001_gene2783	2.17e-222	698.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,2K0KV@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
WH3_k127_2682301_5	1479239.JQMU01000001_gene2782	8.567e-136	436.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,2K1PI@204457|Sphingomonadales	204457|Sphingomonadales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WH3_k127_2682301_10	1248917.ANFX01000010_gene213	2.06e-39	153.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2UCIP@28211|Alphaproteobacteria,2K5YU@204457|Sphingomonadales	204457|Sphingomonadales	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
WH3_k127_2682301_0	1479239.JQMU01000001_gene2780	0.0	1066.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,2K005@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WH3_k127_2682301_7	1479239.JQMU01000001_gene2779	3.534e-90	298.0	COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria,2K4JU@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the small heat shock protein (HSP20) family	ibpA	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
WH3_k127_2682301_11	1248917.ANFX01000010_gene216	3.554e-39	149.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,2K5VT@204457|Sphingomonadales	204457|Sphingomonadales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
WH3_k127_2682301_6	1122970.AUHC01000001_gene547	1.49e-128	418.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,2K16U@204457|Sphingomonadales	204457|Sphingomonadales	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
WH3_k127_2682301_8	1248917.ANFX01000010_gene218	9.658e-76	257.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria,2K54Q@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
WH3_k127_2682301_4	1248917.ANFX01000010_gene219	1.093e-199	628.0	COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,2TVQU@28211|Alphaproteobacteria,2K0DS@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_2682301_1	1479239.JQMU01000001_gene2774	3.244e-234	730.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2TR02@28211|Alphaproteobacteria,2K124@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_2682301_9	1479239.JQMU01000001_gene2773	2.657e-40	151.0	COG2919@1|root,COG2919@2|Bacteria,1NGSW@1224|Proteobacteria,2UJYE@28211|Alphaproteobacteria,2K7B8@204457|Sphingomonadales	204457|Sphingomonadales	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
WH3_k127_2682301_3	1248917.ANFX01000010_gene223	2.733e-212	663.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,2K0VG@204457|Sphingomonadales	204457|Sphingomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WH3_k127_2682301_12	1479239.JQMU01000001_gene2771	7.133e-37	139.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,2JZYC@204457|Sphingomonadales	204457|Sphingomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
WH3_k127_2720786_0	1479239.JQMU01000001_gene999	9.902e-294	907.0	COG0183@1|root,COG0183@2|Bacteria,1MVPC@1224|Proteobacteria,2VEVD@28211|Alphaproteobacteria,2K31W@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
WH3_k127_2720786_1	1280949.HAD_09100	5.641e-14	71.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria,43Z78@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	MA20_45145	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_2820587_0	1248917.ANFX01000025_gene1267	5.049e-277	856.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,2K0VF@204457|Sphingomonadales	204457|Sphingomonadales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
WH3_k127_2820587_3	1479239.JQMU01000001_gene2744	6.563e-168	532.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2TV3E@28211|Alphaproteobacteria,2JZZA@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
WH3_k127_2820587_4	1248917.ANFX01000025_gene1269	2.675e-100	331.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,2K3VU@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WH3_k127_2820587_2	1248917.ANFX01000025_gene1270	6.802e-175	556.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,2K17Y@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S11 family	dac	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
WH3_k127_2820587_1	1479239.JQMU01000001_gene2741	1.285e-188	593.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRP0@28211|Alphaproteobacteria,2K0TV@204457|Sphingomonadales	204457|Sphingomonadales	M	Lytic murein transglycosylase	mltB	-	-	-	-	-	-	-	-	-	-	-	SLT_2
WH3_k127_2922162_1	383381.EH30_08235	8.273e-158	503.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTDF@28211|Alphaproteobacteria,2K19J@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N
WH3_k127_2922162_0	1479239.JQMU01000001_gene627	0.0	1267.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,2K0R3@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WH3_k127_2922162_2	1479239.JQMU01000001_gene626	2.291e-30	121.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,2U30N@28211|Alphaproteobacteria,2K5ES@204457|Sphingomonadales	204457|Sphingomonadales	EG	EamA-like transporter family	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
WH3_k127_2968643_3	1479239.JQMU01000001_gene2456	1.347e-30	120.0	COG2850@1|root,COG2850@2|Bacteria,1MXD0@1224|Proteobacteria,2U0CY@28211|Alphaproteobacteria,2K1HD@204457|Sphingomonadales	204457|Sphingomonadales	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
WH3_k127_2968643_1	1479239.JQMU01000001_gene2455	3.872e-171	540.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,2K289@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
WH3_k127_2968643_2	1479239.JQMU01000001_gene2454	8.334e-144	462.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,2K4W9@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WH3_k127_2968643_0	1479239.JQMU01000001_gene2453	1.344e-215	672.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,2K2TY@204457|Sphingomonadales	204457|Sphingomonadales	Q	Retinal pigment epithelial membrane protein	-	-	1.13.11.82	ko:K11159,ko:K21822	-	-	-	-	ko00000,ko01000	-	-	-	RPE65
WH3_k127_2979743_0	1479239.JQMU01000001_gene2107	2.52e-202	631.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,2K0IJ@204457|Sphingomonadales	204457|Sphingomonadales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WH3_k127_2979743_6	1248917.ANFX01000051_gene436	5.413e-46	166.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2UBRZ@28211|Alphaproteobacteria,2K622@204457|Sphingomonadales	204457|Sphingomonadales	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WH3_k127_2979743_1	1479239.JQMU01000001_gene2105	2.571e-153	488.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria,2K00T@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
WH3_k127_2979743_2	1479239.JQMU01000001_gene2103	7.558e-125	405.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2UANG@28211|Alphaproteobacteria,2KDRM@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WH3_k127_2979743_3	1248917.ANFX01000051_gene438	3.213e-108	351.0	COG1435@1|root,COG1435@2|Bacteria,1NJR4@1224|Proteobacteria,2TV1A@28211|Alphaproteobacteria,2K1CD@204457|Sphingomonadales	204457|Sphingomonadales	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WH3_k127_2979743_4	1479239.JQMU01000001_gene2101	9.364e-95	313.0	COG2353@1|root,COG2353@2|Bacteria,1NMX4@1224|Proteobacteria,2UTM6@28211|Alphaproteobacteria,2K65R@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WH3_k127_2979743_5	1248917.ANFX01000051_gene440	2.347e-70	239.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2UCJF@28211|Alphaproteobacteria,2K4FV@204457|Sphingomonadales	204457|Sphingomonadales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WH3_k127_2980095_0	1248917.ANFX01000029_gene2693	1.085e-141	454.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2TVI9@28211|Alphaproteobacteria,2K2GU@204457|Sphingomonadales	204457|Sphingomonadales	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
WH3_k127_2980095_1	1122970.AUHC01000013_gene1083	4.587e-131	424.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,2K2CC@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
WH3_k127_2980095_2	1248917.ANFX01000029_gene2691	1.725e-97	332.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,2K1HB@204457|Sphingomonadales	204457|Sphingomonadales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WH3_k127_2992232_0	1248917.ANFX01000012_gene1822	0.0	1210.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,2K00X@204457|Sphingomonadales	204457|Sphingomonadales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WH3_k127_3015088_0	13689.BV96_02190	9.726e-143	469.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,2K02F@204457|Sphingomonadales	204457|Sphingomonadales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
WH3_k127_3015428_2	1479239.JQMU01000001_gene2157	1.916e-246	765.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,2K365@204457|Sphingomonadales	204457|Sphingomonadales	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WH3_k127_3015428_13	1415166.NONO_c44030	1.036e-10	71.0	COG0346@1|root,COG0346@2|Bacteria,2IFZW@201174|Actinobacteria,4FWQG@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
WH3_k127_3015428_6	1248917.ANFX01000006_gene78	1.001e-144	462.0	COG1082@1|root,COG1082@2|Bacteria,1RI1Y@1224|Proteobacteria,2UCVK@28211|Alphaproteobacteria,2K4VU@204457|Sphingomonadales	204457|Sphingomonadales	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
WH3_k127_3015428_7	1479239.JQMU01000001_gene1518	3.54e-141	450.0	COG1028@1|root,COG1028@2|Bacteria,1MXWI@1224|Proteobacteria,2TQQ6@28211|Alphaproteobacteria,2K41S@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WH3_k127_3015428_0	1479239.JQMU01000001_gene1519	6.135e-307	955.0	COG4638@1|root,COG4638@2|Bacteria,1R4IX@1224|Proteobacteria,2U0IQ@28211|Alphaproteobacteria,2K1CE@204457|Sphingomonadales	204457|Sphingomonadales	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
WH3_k127_3015428_9	383381.EH30_15540	4.464e-92	328.0	COG0346@1|root,COG0346@2|Bacteria,1MWHG@1224|Proteobacteria,2U7Y3@28211|Alphaproteobacteria,2K4EN@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
WH3_k127_3015428_5	1248917.ANFX01000006_gene82	5.903e-171	538.0	COG2197@1|root,COG2197@2|Bacteria,1R6UF@1224|Proteobacteria,2TU0V@28211|Alphaproteobacteria,2K2AM@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WH3_k127_3015428_1	1479239.JQMU01000001_gene1522	8.632e-303	934.0	COG0318@1|root,COG0318@2|Bacteria,1MVJ1@1224|Proteobacteria,2TUQ9@28211|Alphaproteobacteria,2K3JP@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_3015428_11	1248917.ANFX01000029_gene2703	3.532e-79	266.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2U78G@28211|Alphaproteobacteria,2K4FM@204457|Sphingomonadales	204457|Sphingomonadales	S	dioxygenase of extradiol dioxygenase family	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
WH3_k127_3015428_8	1479239.JQMU01000001_gene1694	1.261e-129	416.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,2K0C9@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_2,GST_N_3
WH3_k127_3015428_10	1122970.AUHC01000013_gene1077	1.401e-86	287.0	COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2U7QQ@28211|Alphaproteobacteria,2K4VJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WH3_k127_3015428_4	1248917.ANFX01000029_gene2698	1.699e-213	668.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,2K0C3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
WH3_k127_3015428_3	1248917.ANFX01000029_gene2697	5.565e-244	758.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TUFB@28211|Alphaproteobacteria,2K0FM@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
WH3_k127_3015428_12	1479239.JQMU01000001_gene1689	8.944e-20	89.0	2EQ70@1|root,33HT9@2|Bacteria,1NIHT@1224|Proteobacteria,2UK3J@28211|Alphaproteobacteria,2K5XI@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3018616_0	1479239.JQMU01000001_gene251	3.647e-265	822.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0CY@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
WH3_k127_3018616_1	1479239.JQMU01000001_gene252	3.237e-81	274.0	2AM8F@1|root,31C39@2|Bacteria,1N008@1224|Proteobacteria,2UCNF@28211|Alphaproteobacteria,2K748@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3018616_2	1479239.JQMU01000001_gene253	3.853e-56	201.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,2K0VP@204457|Sphingomonadales	204457|Sphingomonadales	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
WH3_k127_3023873_4	1248917.ANFX01000032_gene1007	1.678e-38	144.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2TQMA@28211|Alphaproteobacteria,2K0ZR@204457|Sphingomonadales	204457|Sphingomonadales	C	oxidase, subunit	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
WH3_k127_3023873_1	1248917.ANFX01000032_gene1008	9.228e-206	645.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,2K0H9@204457|Sphingomonadales	204457|Sphingomonadales	C	oxidase, subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
WH3_k127_3023873_3	1479239.JQMU01000001_gene813	3.569e-57	202.0	COG3011@1|root,COG3011@2|Bacteria,1Q3II@1224|Proteobacteria,2UFWG@28211|Alphaproteobacteria,2K6D2@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
WH3_k127_3023873_0	1479239.JQMU01000001_gene812	9.442e-249	769.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TUPN@28211|Alphaproteobacteria,2KD37@204457|Sphingomonadales	204457|Sphingomonadales	C	FMN-dependent dehydrogenase	-	-	1.13.12.4	ko:K00467	ko00620,map00620	-	R00319	RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
WH3_k127_3023873_2	1479239.JQMU01000001_gene810	9.788e-130	415.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH3_k127_3053380_2	1479239.JQMU01000001_gene1660	1.76e-131	420.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,2JZXA@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WH3_k127_3053380_1	1248917.ANFX01000021_gene1680	7.409e-140	450.0	COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,2U3QT@28211|Alphaproteobacteria,2K2SB@204457|Sphingomonadales	204457|Sphingomonadales	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WH3_k127_3053380_0	1479239.JQMU01000001_gene1658	2.412e-181	569.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2K0PV@204457|Sphingomonadales	204457|Sphingomonadales	C	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WH3_k127_3058957_0	1248917.ANFX01000030_gene563	0.0	1229.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,2K1R8@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
WH3_k127_3066130_0	1479239.JQMU01000001_gene2862	1.251e-175	552.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria,2K026@204457|Sphingomonadales	204457|Sphingomonadales	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
WH3_k127_3066130_1	1479239.JQMU01000001_gene2863	2.514e-115	373.0	COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,2TVK6@28211|Alphaproteobacteria,2K3BC@204457|Sphingomonadales	204457|Sphingomonadales	E	N-formylglutamate amidohydrolase	-	-	3.5.1.68	ko:K01458	ko00340,ko00630,map00340,map00630	-	R00525	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	FGase
WH3_k127_3106169_0	1044.EH31_00765	1.698e-237	741.0	COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,2TUDY@28211|Alphaproteobacteria,2K1Q2@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117
WH3_k127_3106169_1	1248917.ANFX01000022_gene693	1.049e-95	318.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,2KCNU@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH3_k127_3125911_6	1248917.ANFX01000047_gene1604	1.77e-70	242.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2K4J0@204457|Sphingomonadales	204457|Sphingomonadales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WH3_k127_3125911_1	1479239.JQMU01000001_gene572	1.625e-220	685.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2TSI0@28211|Alphaproteobacteria,2K0R2@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WH3_k127_3125911_5	1248917.ANFX01000047_gene1602	3.942e-72	244.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2U717@28211|Alphaproteobacteria,2K3VT@204457|Sphingomonadales	204457|Sphingomonadales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WH3_k127_3125911_7	1479239.JQMU01000001_gene574	9.289e-68	231.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,2K4E3@204457|Sphingomonadales	204457|Sphingomonadales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WH3_k127_3125911_3	1122970.AUHC01000001_gene801	7.153e-92	310.0	COG3832@1|root,COG3832@2|Bacteria,1RH7Z@1224|Proteobacteria,2U9E1@28211|Alphaproteobacteria,2K54H@204457|Sphingomonadales	204457|Sphingomonadales	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
WH3_k127_3125911_2	1479239.JQMU01000001_gene576	2.36e-131	421.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,2JZW8@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WH3_k127_3125911_0	1479239.JQMU01000001_gene577	1.878e-275	849.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2TQMT@28211|Alphaproteobacteria,2JZY0@204457|Sphingomonadales	204457|Sphingomonadales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WH3_k127_3125911_4	1248917.ANFX01000023_gene1188	2.014e-76	258.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2U79D@28211|Alphaproteobacteria,2K40W@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
WH3_k127_3163720_1	1479239.JQMU01000001_gene2141	3.996e-113	366.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2TQXQ@28211|Alphaproteobacteria,2K039@204457|Sphingomonadales	204457|Sphingomonadales	U	MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
WH3_k127_3163720_2	1248917.ANFX01000020_gene2233	7.991e-65	226.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,2K53V@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
WH3_k127_3163720_0	1248917.ANFX01000020_gene2232	8.12e-114	374.0	COG5373@1|root,COG5373@2|Bacteria,1N5K2@1224|Proteobacteria,2UB74@28211|Alphaproteobacteria,2JZY7@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	tolA	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3163720_3	1248917.ANFX01000020_gene2231	1.383e-38	149.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2K1NT@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WH3_k127_3170704_0	1248917.ANFX01000038_gene573	0.0	1267.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,2K0IA@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WH3_k127_3170704_1	1122970.AUHC01000005_gene1949	1.215e-50	182.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,2K1SR@204457|Sphingomonadales	204457|Sphingomonadales	J	Polynucleotide adenylyltransferase	cca	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd
WH3_k127_3220173_2	1479239.JQMU01000001_gene2818	1.762e-28	113.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,2K0QX@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
WH3_k127_3220173_0	1479239.JQMU01000001_gene2817	4.017e-142	451.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,2K18U@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH dehydrogenase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WH3_k127_3220173_1	1479239.JQMU01000001_gene2813	4.445e-84	280.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria,2JZYB@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WH3_k127_3222337_0	1248917.ANFX01000043_gene2725	3.179e-260	808.0	COG0477@1|root,COG0477@2|Bacteria,1QYXQ@1224|Proteobacteria,2TY0X@28211|Alphaproteobacteria,2KEK5@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_3222337_1	1248917.ANFX01000043_gene2724	4.413e-135	432.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2TU7F@28211|Alphaproteobacteria,2K0K0@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
WH3_k127_3222337_3	1248917.ANFX01000043_gene2723	1.311e-58	210.0	2AI43@1|root,318I3@2|Bacteria,1NCMB@1224|Proteobacteria,2UFPI@28211|Alphaproteobacteria,2K76K@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3222337_2	1479239.JQMU01000001_gene1308	2.48e-73	247.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,2K0YD@204457|Sphingomonadales	204457|Sphingomonadales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
WH3_k127_3374199_0	1479239.JQMU01000001_gene217	5.329e-116	376.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,2K1DQ@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WH3_k127_3374199_5	1479239.JQMU01000001_gene216	1.507e-74	254.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,2K4I6@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WH3_k127_3374199_1	1479239.JQMU01000001_gene215	9.123e-87	288.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,2K4H2@204457|Sphingomonadales	204457|Sphingomonadales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WH3_k127_3374199_2	1248917.ANFX01000027_gene1119	1.117e-85	286.0	COG4278@1|root,COG4278@2|Bacteria,1RKAG@1224|Proteobacteria,2U3DR@28211|Alphaproteobacteria,2K4R3@204457|Sphingomonadales	204457|Sphingomonadales	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3374199_3	1248917.ANFX01000027_gene1120	8.674e-84	287.0	2DPW6@1|root,333NE@2|Bacteria,1RKH2@1224|Proteobacteria,2UAYE@28211|Alphaproteobacteria,2K5NB@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3374199_4	1479239.JQMU01000001_gene212	1.279e-82	275.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2TYHX@28211|Alphaproteobacteria,2K0ZW@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.7	ko:K01502	ko00643,ko01120,map00643,map01120	-	R05358	RC01336	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WH3_k127_3389154_2	1479239.JQMU01000001_gene851	2.291e-36	138.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2K5Z5@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WH3_k127_3389154_3	1479239.JQMU01000001_gene850	2.842e-27	113.0	29DN7@1|root,300K0@2|Bacteria,1P64V@1224|Proteobacteria,2UYQF@28211|Alphaproteobacteria,2KBXA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3389154_0	1479239.JQMU01000001_gene848	2.074e-205	644.0	COG0415@1|root,COG0415@2|Bacteria,1MUKB@1224|Proteobacteria,2TR6A@28211|Alphaproteobacteria,2K01T@204457|Sphingomonadales	204457|Sphingomonadales	L	FAD binding domain of DNA photolyase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_7
WH3_k127_3389154_1	1479239.JQMU01000001_gene846	9.834e-51	184.0	COG3650@1|root,COG3650@2|Bacteria,1NH2D@1224|Proteobacteria,2UKQE@28211|Alphaproteobacteria,2K6G8@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3389154_4	1479239.JQMU01000001_gene845	1.766e-08	57.0	COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,2UC83@28211|Alphaproteobacteria,2K5XY@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
WH3_k127_3416320_3	1479239.JQMU01000001_gene505	2.546e-38	149.0	2BPS1@1|root,32IJB@2|Bacteria,1PD6R@1224|Proteobacteria,2V6HD@28211|Alphaproteobacteria,2KAIN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3416320_1	1479239.JQMU01000001_gene504	4.507e-64	226.0	2CIKP@1|root,309WD@2|Bacteria,1P8FJ@1224|Proteobacteria,2UYNE@28211|Alphaproteobacteria,2K7SV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3416320_2	1248917.ANFX01000037_gene2135	1.152e-48	176.0	COG1605@1|root,COG1605@2|Bacteria,1MZTQ@1224|Proteobacteria,2UCMC@28211|Alphaproteobacteria,2K610@204457|Sphingomonadales	204457|Sphingomonadales	E	chorismate mutase	-	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
WH3_k127_3416320_0	1248917.ANFX01000037_gene2136	1.485e-86	290.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,2JZY9@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
WH3_k127_3474245_3	1479239.JQMU01000001_gene2501	8.811e-57	202.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,2K5A0@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WH3_k127_3474245_4	1479239.JQMU01000001_gene2502	7.649e-48	171.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria,2K60H@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WH3_k127_3474245_2	1248917.ANFX01000037_gene2067	1.156e-68	239.0	COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,2UG72@28211|Alphaproteobacteria,2K4XG@204457|Sphingomonadales	204457|Sphingomonadales	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH3_k127_3474245_0	237727.NAP1_02130	2.891e-93	309.0	COG1309@1|root,COG1309@2|Bacteria,1RFAI@1224|Proteobacteria,2U84A@28211|Alphaproteobacteria,2KDB5@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WH3_k127_3474245_1	1479239.JQMU01000001_gene2505	6.048e-78	262.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,2K18B@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminomethyltransferase	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
WH3_k127_3475250_1	1479239.JQMU01000001_gene155	2.718e-59	215.0	2DC1J@1|root,333E1@2|Bacteria,1N2JX@1224|Proteobacteria,2UE17@28211|Alphaproteobacteria,2K65P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3475250_0	1479239.JQMU01000001_gene154	1.993e-157	499.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,2K20W@204457|Sphingomonadales	204457|Sphingomonadales	S	metalloprotease	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
WH3_k127_3475250_2	1479239.JQMU01000001_gene153	1.559e-48	179.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,2K16P@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
WH3_k127_3496056_1	158500.BV97_02543	1.795e-122	401.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2U0FQ@28211|Alphaproteobacteria,2K06C@204457|Sphingomonadales	204457|Sphingomonadales	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
WH3_k127_3496056_0	1248917.ANFX01000021_gene1691	1.645e-137	439.0	COG1629@1|root,COG4771@2|Bacteria,1R9TW@1224|Proteobacteria,2TTKV@28211|Alphaproteobacteria,2K20Z@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_3534956_3	1248917.ANFX01000005_gene132	2.401e-14	73.0	COG3631@1|root,COG3631@2|Bacteria,1RHRD@1224|Proteobacteria,2U9AT@28211|Alphaproteobacteria,2K50G@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WH3_k127_3534956_1	1248917.ANFX01000005_gene131	9.484e-128	411.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2U1D8@28211|Alphaproteobacteria,2K0IT@204457|Sphingomonadales	204457|Sphingomonadales	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
WH3_k127_3534956_2	1248917.ANFX01000005_gene130	1.089e-38	145.0	2EMU4@1|root,33FGG@2|Bacteria,1NNB6@1224|Proteobacteria,2UMJV@28211|Alphaproteobacteria,2K6U1@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3534956_0	1479239.JQMU01000001_gene1423	4.745e-146	466.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,2K0HT@204457|Sphingomonadales	204457|Sphingomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WH3_k127_3544060_4	1248917.ANFX01000005_gene132	5.272e-64	220.0	COG3631@1|root,COG3631@2|Bacteria,1RHRD@1224|Proteobacteria,2U9AT@28211|Alphaproteobacteria,2K50G@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WH3_k127_3544060_3	1248917.ANFX01000005_gene134	4.666e-68	232.0	COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,2UFF4@28211|Alphaproteobacteria,2K5XV@204457|Sphingomonadales	204457|Sphingomonadales	S	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
WH3_k127_3544060_0	1479239.JQMU01000001_gene1428	8.07e-264	817.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,2K1UD@204457|Sphingomonadales	204457|Sphingomonadales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WH3_k127_3544060_2	1479239.JQMU01000001_gene1429	3.137e-76	257.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2U987@28211|Alphaproteobacteria,2K4J9@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
WH3_k127_3544060_1	1248917.ANFX01000005_gene137	2.324e-143	457.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria,2JZZP@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WH3_k127_3546117_1	1479239.JQMU01000001_gene612	8.892e-93	307.0	COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,2K120@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WH3_k127_3546117_0	1479239.JQMU01000001_gene611	6.986e-180	569.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,2K1FE@204457|Sphingomonadales	204457|Sphingomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH3_k127_3552227_3	1479239.JQMU01000001_gene818	3.706e-139	445.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,2K3UQ@204457|Sphingomonadales	204457|Sphingomonadales	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
WH3_k127_3552227_1	1122970.AUHC01000014_gene1145	9.687e-241	748.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2TW6Z@28211|Alphaproteobacteria,2K064@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442,Pyr_redox_2
WH3_k127_3552227_7	1479239.JQMU01000001_gene820	7.719e-65	229.0	COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2UD2M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	blh	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442
WH3_k127_3552227_6	1479239.JQMU01000001_gene821	4.539e-67	237.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2U99K@28211|Alphaproteobacteria,2K6HP@204457|Sphingomonadales	204457|Sphingomonadales	S	transporter component	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3552227_5	1479239.JQMU01000001_gene822	2.517e-71	243.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,2K5A8@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WH3_k127_3552227_2	1122970.AUHC01000014_gene1149	1.15e-176	557.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2K06J@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH3_k127_3552227_4	1479239.JQMU01000001_gene824	9.168e-117	378.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,2K4CA@204457|Sphingomonadales	204457|Sphingomonadales	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
WH3_k127_3552227_10	1479239.JQMU01000001_gene825	1.722e-43	161.0	COG0640@1|root,COG0640@2|Bacteria,1NSV9@1224|Proteobacteria,2UCDX@28211|Alphaproteobacteria,2K7HX@204457|Sphingomonadales	204457|Sphingomonadales	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
WH3_k127_3552227_0	1479239.JQMU01000001_gene380	6.364e-304	940.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TST2@28211|Alphaproteobacteria,2K189@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WH3_k127_3552227_8	382464.ABSI01000009_gene4000	2.124e-50	193.0	COG0715@1|root,COG0715@2|Bacteria,46U6U@74201|Verrucomicrobia,2IU8C@203494|Verrucomicrobiae	2|Bacteria	P	Protein of unknown function (DUF3500)	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	DUF3500,VitK2_biosynth
WH3_k127_3552227_11	1280949.HAD_10300	5.278e-11	66.0	COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria,43XDJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH3_k127_3552227_9	279238.Saro_2119	1.255e-49	183.0	2DPIB@1|root,3326Z@2|Bacteria,1NHPZ@1224|Proteobacteria,2UTAH@28211|Alphaproteobacteria,2KAT0@204457|Sphingomonadales	204457|Sphingomonadales	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
WH3_k127_3570312_0	1479239.JQMU01000001_gene2579	8.095e-273	846.0	COG0642@1|root,COG2205@2|Bacteria,1QVQF@1224|Proteobacteria,2TWX1@28211|Alphaproteobacteria,2KEEV@204457|Sphingomonadales	204457|Sphingomonadales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c
WH3_k127_3570312_1	1479239.JQMU01000001_gene2580	2.001e-229	713.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH3_k127_3588722_0	1479239.JQMU01000001_gene2266	0.0	1270.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2K0C4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
WH3_k127_3588722_1	1479239.JQMU01000001_gene2267	5.355e-90	304.0	COG3772@1|root,COG3772@2|Bacteria,1MZJD@1224|Proteobacteria,2U7X4@28211|Alphaproteobacteria,2K9AH@204457|Sphingomonadales	204457|Sphingomonadales	G	lysozyme	-	-	3.2.1.17	ko:K01185	-	-	-	-	ko00000,ko01000	-	-	-	Phage_lysozyme
WH3_k127_3588722_3	1248917.ANFX01000012_gene1859	1.19e-34	133.0	COG1476@1|root,COG1476@2|Bacteria,1N6SS@1224|Proteobacteria,2UU1H@28211|Alphaproteobacteria,2K7AQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
WH3_k127_3588722_2	1479239.JQMU01000001_gene2269	3.437e-87	294.0	2AM5I@1|root,31BZX@2|Bacteria,1P26J@1224|Proteobacteria,2UU74@28211|Alphaproteobacteria,2K6V6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3588722_4	1479239.JQMU01000001_gene2270	4.012e-22	96.0	COG4625@1|root,COG5640@1|root,COG4625@2|Bacteria,COG5640@2|Bacteria,1NS3H@1224|Proteobacteria,2U1SB@28211|Alphaproteobacteria,2K2MI@204457|Sphingomonadales	204457|Sphingomonadales	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR,Peptidase_S8,Trypsin
WH3_k127_3594513_3	1248917.ANFX01000029_gene2653	1.125e-129	419.0	29X0I@1|root,30INU@2|Bacteria,1PNCD@1224|Proteobacteria,2V0YC@28211|Alphaproteobacteria,2KAXI@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3594513_0	383381.EH30_01380	0.0	1647.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,2K0N3@204457|Sphingomonadales	204457|Sphingomonadales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WH3_k127_3594513_1	1479239.JQMU01000001_gene1979	8.526e-179	608.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2K10W@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WH3_k127_3594513_2	1479239.JQMU01000001_gene1980	3.78e-149	474.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2K11G@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WH3_k127_3594513_4	1479239.JQMU01000001_gene1981	1.058e-121	392.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,2K12E@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WH3_k127_3627907_5	1502850.FG91_03347	4.959e-13	69.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,2K4E6@204457|Sphingomonadales	204457|Sphingomonadales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
WH3_k127_3627907_3	1479239.JQMU01000001_gene1490	6.707e-50	179.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,2K561@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WH3_k127_3627907_1	1479239.JQMU01000001_gene1489	2.779e-147	473.0	COG4246@1|root,COG4246@2|Bacteria,1N7Y1@1224|Proteobacteria,2TTZW@28211|Alphaproteobacteria,2K10G@204457|Sphingomonadales	204457|Sphingomonadales	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
WH3_k127_3627907_4	1479239.JQMU01000001_gene1488	6.163e-31	122.0	COG3908@1|root,COG3908@2|Bacteria,1N7PA@1224|Proteobacteria,2UFTN@28211|Alphaproteobacteria,2K6ZC@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2093)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2093
WH3_k127_3627907_0	1479239.JQMU01000001_gene1487	2.249e-257	801.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria,2K05G@204457|Sphingomonadales	204457|Sphingomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WH3_k127_3627907_2	317655.Sala_3104	5.417e-123	404.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,2K0GD@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WH3_k127_3628427_2	1479239.JQMU01000001_gene1127	5.258e-175	550.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria,2JZZK@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
WH3_k127_3628427_5	1479239.JQMU01000001_gene1128	4.531e-39	150.0	2AMA4@1|root,31C51@2|Bacteria,1Q84C@1224|Proteobacteria,2VEA1@28211|Alphaproteobacteria,2KC28@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3628427_1	1479239.JQMU01000001_gene1130	8.916e-306	943.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2U0WI@28211|Alphaproteobacteria,2K09R@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_3628427_4	1248917.ANFX01000013_gene1411	1.155e-89	304.0	COG2120@1|root,COG2120@2|Bacteria,1NKPM@1224|Proteobacteria,2UKN3@28211|Alphaproteobacteria,2K4GT@204457|Sphingomonadales	204457|Sphingomonadales	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WH3_k127_3628427_0	1479239.JQMU01000001_gene1132	0.0	1535.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,2K0E4@204457|Sphingomonadales	204457|Sphingomonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WH3_k127_3628427_3	1479239.JQMU01000001_gene1133	1.533e-134	432.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,2K0BX@204457|Sphingomonadales	204457|Sphingomonadales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WH3_k127_3718451_1	1122970.AUHC01000009_gene234	1.941e-227	710.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2TRVS@28211|Alphaproteobacteria,2K20M@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glycosyl hydrolase 13 family	glgX_2	-	3.2.1.196	ko:K02438	ko00500,ko01100,map00500,map01100	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
WH3_k127_3718451_0	1122970.AUHC01000002_gene1445	0.0	1129.0	COG1629@1|root,COG4771@2|Bacteria,1MUNK@1224|Proteobacteria,2TRCG@28211|Alphaproteobacteria,2K0ND@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_3733241_8	1248917.ANFX01000029_gene2630	6.327e-42	154.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2KCVI@204457|Sphingomonadales	204457|Sphingomonadales	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WH3_k127_3733241_4	1479239.JQMU01000001_gene1896	4.072e-164	516.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2K1HY@204457|Sphingomonadales	204457|Sphingomonadales	G	Aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
WH3_k127_3733241_2	1479239.JQMU01000001_gene1895	7.574e-215	677.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2TS4Z@28211|Alphaproteobacteria,2KCZX@204457|Sphingomonadales	204457|Sphingomonadales	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WH3_k127_3733241_0	1479239.JQMU01000001_gene1894	0.0	1328.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2K0Z1@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis protein	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
WH3_k127_3733241_6	1479239.JQMU01000001_gene1893	9.351e-70	239.0	COG0835@1|root,COG0835@2|Bacteria,1N88R@1224|Proteobacteria,2UGI7@28211|Alphaproteobacteria,2K55G@204457|Sphingomonadales	204457|Sphingomonadales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WH3_k127_3733241_7	237727.NAP1_15873	1.962e-67	230.0	COG2199@1|root,COG3706@2|Bacteria,1RH2K@1224|Proteobacteria,2U9EP@28211|Alphaproteobacteria,2K4IT@204457|Sphingomonadales	204457|Sphingomonadales	T	chemotaxis	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WH3_k127_3733241_3	1479239.JQMU01000001_gene1891	5.074e-176	564.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2TSGV@28211|Alphaproteobacteria,2K0GS@204457|Sphingomonadales	204457|Sphingomonadales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WH3_k127_3733241_5	1479239.JQMU01000001_gene1890	1.188e-157	505.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2TRQ3@28211|Alphaproteobacteria,2K3X1@204457|Sphingomonadales	204457|Sphingomonadales	NT	COG1352 Methylase of chemotaxis methyl-accepting proteins	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR
WH3_k127_3733241_1	1479239.JQMU01000001_gene1889	3.847e-228	712.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TS9V@28211|Alphaproteobacteria,2K1VI@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF
WH3_k127_3734603_0	383381.EH30_14840	2.044e-289	897.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2K0PZ@204457|Sphingomonadales	204457|Sphingomonadales	E	gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WH3_k127_3734603_1	1248917.ANFX01000013_gene1491	6.269e-64	220.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria,2K1QF@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WH3_k127_3751799_1	1479239.JQMU01000001_gene1266	1.211e-121	395.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2K4X5@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH3_k127_3751799_0	1479239.JQMU01000001_gene1267	6.261e-319	979.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TRRZ@28211|Alphaproteobacteria,2K2K3@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_3751799_2	1248917.ANFX01000013_gene1588	3.781e-92	308.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TU15@28211|Alphaproteobacteria,2K1GE@204457|Sphingomonadales	204457|Sphingomonadales	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_3858410_1	1479239.JQMU01000001_gene1347	6.438e-218	679.0	COG2733@1|root,COG2733@2|Bacteria,1MX3G@1224|Proteobacteria,2U15J@28211|Alphaproteobacteria,2K0FY@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
WH3_k127_3858410_0	1479239.JQMU01000001_gene1348	0.0	1763.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K0BI@204457|Sphingomonadales	204457|Sphingomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WH3_k127_3873693_2	1479239.JQMU01000001_gene1231	8.012e-53	188.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2UJ22@28211|Alphaproteobacteria,2KD76@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the Fur family	-	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
WH3_k127_3873693_1	1479239.JQMU01000001_gene1230	1.399e-118	384.0	COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2TTDD@28211|Alphaproteobacteria,2K3XP@204457|Sphingomonadales	204457|Sphingomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA_1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WH3_k127_3873693_0	1248917.ANFX01000013_gene1543	5.055e-303	936.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,2K0R5@204457|Sphingomonadales	204457|Sphingomonadales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WH3_k127_3873693_3	1479239.JQMU01000001_gene1227	1.155e-41	153.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,2K1RQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Heparinase	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
WH3_k127_3956265_1	1248917.ANFX01000012_gene1867	2.908e-54	196.0	2ANQE@1|root,31DQ0@2|Bacteria,1MWJD@1224|Proteobacteria,2U7P7@28211|Alphaproteobacteria,2K5A1@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4163
WH3_k127_3956265_0	1479239.JQMU01000001_gene2276	3.963e-171	539.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,2JZV7@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the peptidase M17 family	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
WH3_k127_3978238_3	1479239.JQMU01000001_gene1924	3.843e-34	132.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2K0IX@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WH3_k127_3978238_0	1248917.ANFX01000007_gene54	0.0	1333.0	COG4773@1|root,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2UQ22@28211|Alphaproteobacteria,2KEG3@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_3978238_2	1479239.JQMU01000001_gene1927	2.619e-106	347.0	COG1309@1|root,COG1309@2|Bacteria,1RE97@1224|Proteobacteria,2U8N9@28211|Alphaproteobacteria,2K3XR@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WH3_k127_3978238_1	1479239.JQMU01000001_gene1930	7.728e-111	364.0	COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2TRH2@28211|Alphaproteobacteria,2JZZU@204457|Sphingomonadales	204457|Sphingomonadales	S	PKHD-type hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_3
WH3_k127_3978238_4	383381.EH30_00680	1.112e-22	98.0	2DD6Y@1|root,2ZGTY@2|Bacteria,1R846@1224|Proteobacteria,2TS2F@28211|Alphaproteobacteria,2K0KP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_3979681_3	1479239.JQMU01000001_gene1550	1.942e-81	273.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2U139@28211|Alphaproteobacteria,2K18J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
WH3_k127_3979681_2	1479239.JQMU01000001_gene1549	8.537e-132	429.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,2JZYQ@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_3979681_1	1479239.JQMU01000001_gene1548	8.759e-212	666.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria,2K1A6@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH3_k127_3979681_4	1248916.ANFY01000007_gene2556	2.099e-61	218.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N
WH3_k127_3979681_5	1331060.RLDS_25460	6.619e-53	193.0	COG3637@1|root,COG3637@2|Bacteria,1NJWW@1224|Proteobacteria,2UD8G@28211|Alphaproteobacteria,2K5ZH@204457|Sphingomonadales	204457|Sphingomonadales	M	OmpA-like transmembrane domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
WH3_k127_3979681_0	517722.AEUE01000008_gene89	0.0	1065.0	COG4625@1|root,COG4625@2|Bacteria,1N0PT@1224|Proteobacteria,2TTFH@28211|Alphaproteobacteria,2K0XX@204457|Sphingomonadales	204457|Sphingomonadales	EQ	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
WH3_k127_3979681_6	158500.BV97_01264	1.215e-43	162.0	COG1629@1|root,COG4771@2|Bacteria,1MXD7@1224|Proteobacteria,2U07R@28211|Alphaproteobacteria,2KECN@204457|Sphingomonadales	204457|Sphingomonadales	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,STN,TonB_dep_Rec
WH3_k127_4000218_2	1479239.JQMU01000001_gene236	2.329e-154	490.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,2K0GV@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WH3_k127_4000218_1	1479239.JQMU01000001_gene235	6.347e-221	704.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,2K2Y2@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WH3_k127_4000218_3	1479239.JQMU01000001_gene234	7.696e-139	447.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,2K0WQ@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WH3_k127_4000218_0	1479239.JQMU01000001_gene233	0.0	1480.0	COG2911@1|root,COG2911@2|Bacteria,1R6VP@1224|Proteobacteria,2U46Q@28211|Alphaproteobacteria,2KCIH@204457|Sphingomonadales	204457|Sphingomonadales	S	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
WH3_k127_4000218_5	1479239.JQMU01000001_gene232	1.312e-23	104.0	2AKQN@1|root,31BHD@2|Bacteria,1Q7C6@1224|Proteobacteria,2UJNT@28211|Alphaproteobacteria,2K6TW@204457|Sphingomonadales	204457|Sphingomonadales	S	YnbE-like lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
WH3_k127_4000218_4	1479239.JQMU01000001_gene231	9.069e-57	199.0	COG3784@1|root,COG3784@2|Bacteria,1Q09W@1224|Proteobacteria,2UCIH@28211|Alphaproteobacteria,2K5RZ@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
WH3_k127_4031431_3	1479239.JQMU01000001_gene2800	4.467e-186	586.0	COG1196@1|root,COG1196@2|Bacteria,1MVEP@1224|Proteobacteria,2TR50@28211|Alphaproteobacteria,2K0N2@204457|Sphingomonadales	204457|Sphingomonadales	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4031431_6	1248917.ANFX01000031_gene2584	5.464e-45	164.0	COG5454@1|root,COG5454@2|Bacteria,1N8U9@1224|Proteobacteria,2UGCD@28211|Alphaproteobacteria,2K711@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1467
WH3_k127_4031431_0	1479239.JQMU01000001_gene2802	0.0	1026.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,2TQTR@28211|Alphaproteobacteria,2K04C@204457|Sphingomonadales	204457|Sphingomonadales	S	metallo-beta-lactamase	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
WH3_k127_4031431_4	1479239.JQMU01000001_gene2803	4.231e-160	505.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2TS5A@28211|Alphaproteobacteria,2K0SW@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WH3_k127_4031431_5	1479239.JQMU01000001_gene2804	2.294e-110	361.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,2JZZZ@204457|Sphingomonadales	204457|Sphingomonadales	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,BPL_LplA_LipB_2
WH3_k127_4031431_2	1479239.JQMU01000001_gene2805	3.419e-278	859.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,2K08E@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
WH3_k127_4031431_1	1479239.JQMU01000001_gene2806	2.821e-300	925.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,2K0EQ@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH ubiquinone oxidoreductase subunit	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WH3_k127_4031431_7	1479239.JQMU01000001_gene2807	3.367e-27	110.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,2K1DM@204457|Sphingomonadales	204457|Sphingomonadales	CP	NADH ubiquinone oxidoreductase subunit	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
WH3_k127_4047308_3	1479239.JQMU01000001_gene2439	2.5e-323	997.0	COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,2K0JT@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WH3_k127_4047308_1	1479239.JQMU01000001_gene2438	0.0	1264.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U10R@28211|Alphaproteobacteria,2K0G1@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_4047308_6	1479239.JQMU01000001_gene2437	1.139e-36	139.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,2K5YV@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
WH3_k127_4047308_5	1479239.JQMU01000001_gene2436	2.773e-132	424.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,2K0NC@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WH3_k127_4047308_0	1479239.JQMU01000001_gene2435	0.0	1304.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
WH3_k127_4047308_2	1479239.JQMU01000001_gene2434	0.0	1118.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,2K017@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WH3_k127_4047308_4	1479239.JQMU01000001_gene2433	5.091e-279	861.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,2K008@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein, ATPase CpaF	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WH3_k127_4092886_4	1122970.AUHC01000002_gene1425	3.324e-14	72.0	COG0475@1|root,COG0475@2|Bacteria,1MVGV@1224|Proteobacteria,2TUCH@28211|Alphaproteobacteria,2K24B@204457|Sphingomonadales	204457|Sphingomonadales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WH3_k127_4092886_0	1248917.ANFX01000040_gene783	1.706e-222	699.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,2K1GI@204457|Sphingomonadales	204457|Sphingomonadales	E	Glycine cleavage system T protein	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WH3_k127_4092886_3	1479239.JQMU01000001_gene904	1.329e-60	210.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,2K5E0@204457|Sphingomonadales	204457|Sphingomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WH3_k127_4092886_1	1248917.ANFX01000040_gene781	2.024e-129	418.0	COG1216@1|root,COG1216@2|Bacteria,1R554@1224|Proteobacteria,2U3P6@28211|Alphaproteobacteria,2K9SK@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
WH3_k127_4092886_2	1379701.JPJC01000258_gene2717	1.18e-78	267.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2TR6C@28211|Alphaproteobacteria,2K0IW@204457|Sphingomonadales	204457|Sphingomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WH3_k127_4093181_2	1248917.ANFX01000012_gene1829	1.706e-36	142.0	COG1024@1|root,COG1024@2|Bacteria,1MVPQ@1224|Proteobacteria,2TTJ4@28211|Alphaproteobacteria,2K20K@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WH3_k127_4093181_1	1248917.ANFX01000012_gene1827	9.017e-156	494.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2TRPN@28211|Alphaproteobacteria,2K13W@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WH3_k127_4093181_0	1479239.JQMU01000001_gene2232	5.303e-219	681.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TSA0@28211|Alphaproteobacteria,2K081@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_4113508_2	1479239.JQMU01000001_gene611	7.295e-40	148.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,2K1FE@204457|Sphingomonadales	204457|Sphingomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH3_k127_4113508_1	1479239.JQMU01000001_gene610	1.715e-199	627.0	COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1MV8J@1224|Proteobacteria,2TTYF@28211|Alphaproteobacteria,2K22B@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
WH3_k127_4113508_0	1479239.JQMU01000001_gene609	3.678e-228	713.0	COG4346@1|root,COG4346@2|Bacteria,1QHX0@1224|Proteobacteria,2TVG5@28211|Alphaproteobacteria,2K03Y@204457|Sphingomonadales	204457|Sphingomonadales	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
WH3_k127_4113846_7	1248917.ANFX01000012_gene1759	1.99e-83	285.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2U1U0@28211|Alphaproteobacteria,2K146@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.199	ko:K15922	-	-	R00802,R11543	RC00028,RC00059,RC00077,RC00451	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
WH3_k127_4113846_0	1248917.ANFX01000012_gene1758	0.0	1198.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U2X6@28211|Alphaproteobacteria,2KEB6@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_4113846_2	1248917.ANFX01000012_gene1757	4.969e-212	664.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2TTHW@28211|Alphaproteobacteria,2KDVX@204457|Sphingomonadales	204457|Sphingomonadales	G	Major Facilitator Superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
WH3_k127_4113846_4	1248917.ANFX01000012_gene1756	3.718e-160	511.0	COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,2TVK9@28211|Alphaproteobacteria,2K1K1@204457|Sphingomonadales	204457|Sphingomonadales	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
WH3_k127_4113846_1	1248917.ANFX01000012_gene1755	6.489e-266	832.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,2K0SB@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
WH3_k127_4113846_5	1248917.ANFX01000012_gene1754	5.046e-102	342.0	COG0431@1|root,COG0431@2|Bacteria,1RB2T@1224|Proteobacteria,2U6RE@28211|Alphaproteobacteria,2K1QH@204457|Sphingomonadales	204457|Sphingomonadales	S	NADPH-dependent FMN reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
WH3_k127_4113846_6	1248917.ANFX01000012_gene1753	1.835e-91	308.0	COG0108@1|root,COG0108@2|Bacteria,1RBRE@1224|Proteobacteria,2U6BU@28211|Alphaproteobacteria,2K4AG@204457|Sphingomonadales	204457|Sphingomonadales	H	3,4-dihydroxy-2-butanone 4-phosphate synthase	-	-	-	-	-	-	-	-	-	-	-	-	DHBP_synthase
WH3_k127_4113846_3	1248917.ANFX01000012_gene1752	2.969e-190	599.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,2K0UU@204457|Sphingomonadales	204457|Sphingomonadales	S	Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
WH3_k127_4127241_3	1479239.JQMU01000001_gene1407	4.699e-91	302.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,2JZXM@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
WH3_k127_4127241_0	1479239.JQMU01000001_gene1406	2.158e-317	979.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,2K2A0@204457|Sphingomonadales	204457|Sphingomonadales	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH3_k127_4127241_1	1479239.JQMU01000001_gene1405	1.081e-199	635.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria,2K011@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
WH3_k127_4127241_2	383381.EH30_15180	4.589e-91	301.0	COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2U97G@28211|Alphaproteobacteria,2K59G@204457|Sphingomonadales	204457|Sphingomonadales	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH3_k127_4127241_4	1248917.ANFX01000005_gene106	5.031e-69	236.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,2K4AW@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WH3_k127_4147773_1	1248917.ANFX01000021_gene1691	1.408e-320	986.0	COG1629@1|root,COG4771@2|Bacteria,1R9TW@1224|Proteobacteria,2TTKV@28211|Alphaproteobacteria,2K20Z@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_4147773_0	1479239.JQMU01000001_gene1828	0.0	1137.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TYSV@28211|Alphaproteobacteria,2K11B@204457|Sphingomonadales	204457|Sphingomonadales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,PAS_3
WH3_k127_4147773_2	1479239.JQMU01000001_gene1827	3.267e-31	124.0	2C19Z@1|root,2Z826@2|Bacteria,1RBG1@1224|Proteobacteria,2UKHV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4154755_4	1479239.JQMU01000001_gene2306	2.52e-69	239.0	COG0457@1|root,COG0457@2|Bacteria,1QNIE@1224|Proteobacteria,2TVQA@28211|Alphaproteobacteria,2K08T@204457|Sphingomonadales	204457|Sphingomonadales	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_19
WH3_k127_4154755_3	1479239.JQMU01000001_gene2307	2.248e-100	327.0	COG5465@1|root,COG5465@2|Bacteria,1REC1@1224|Proteobacteria,2U7UP@28211|Alphaproteobacteria,2K1T3@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
WH3_k127_4154755_2	1479239.JQMU01000001_gene2308	7.301e-118	389.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria,2K353@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
WH3_k127_4154755_1	1479239.JQMU01000001_gene2309	1.412e-129	418.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,2K14K@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
WH3_k127_4154755_0	1479239.JQMU01000001_gene2310	1.786e-134	436.0	2FE0D@1|root,3460K@2|Bacteria,1N3CI@1224|Proteobacteria,2UDQQ@28211|Alphaproteobacteria,2K6KM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4162179_8	1522072.IL54_0744	2.667e-29	123.0	COG1729@1|root,COG1729@2|Bacteria,1R8C4@1224|Proteobacteria,2VBNQ@28211|Alphaproteobacteria,2K0FK@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
WH3_k127_4162179_2	1479239.JQMU01000001_gene1917	4.871e-180	569.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,2K3YA@204457|Sphingomonadales	204457|Sphingomonadales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
WH3_k127_4162179_4	1479239.JQMU01000001_gene1918	1.165e-95	319.0	COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,2UEUN@28211|Alphaproteobacteria,2KDGI@204457|Sphingomonadales	204457|Sphingomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WH3_k127_4162179_0	1479239.JQMU01000001_gene1920	3.328e-273	843.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2TQUS@28211|Alphaproteobacteria,2K1QA@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
WH3_k127_4162179_7	1248917.ANFX01000007_gene61	7.431e-40	149.0	2C91B@1|root,33D4Z@2|Bacteria,1NGZZ@1224|Proteobacteria,2UK78@28211|Alphaproteobacteria,2KDAR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4162179_5	1248917.ANFX01000007_gene60	2.801e-72	247.0	2EC7R@1|root,33669@2|Bacteria,1NQFV@1224|Proteobacteria,2UMAZ@28211|Alphaproteobacteria,2K7H7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4162179_6	1248917.ANFX01000007_gene59	1.839e-69	240.0	29E7I@1|root,3015I@2|Bacteria,1NCJP@1224|Proteobacteria,2UKUZ@28211|Alphaproteobacteria,2K68C@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1761)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1761
WH3_k127_4162179_1	1248917.ANFX01000007_gene58	8.814e-191	601.0	COG1226@1|root,COG1226@2|Bacteria,1MXQP@1224|Proteobacteria,2TTRN@28211|Alphaproteobacteria,2K11P@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
WH3_k127_4162179_3	1479239.JQMU01000001_gene1923	2.608e-154	489.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria,2K0F4@204457|Sphingomonadales	204457|Sphingomonadales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WH3_k127_4200593_1	237727.NAP1_04610	1.186e-142	454.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2K0QB@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH3_k127_4200593_0	1479239.JQMU01000001_gene2591	0.0	1470.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,2JZWI@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WH3_k127_4227919_2	1348657.M622_04850	2.728e-21	93.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VJ1B@28216|Betaproteobacteria,2KWC0@206389|Rhodocyclales	206389|Rhodocyclales	MU	RND efflux system, outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_4227919_0	85643.Tmz1t_0263	3.483e-261	806.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2VJ2W@28216|Betaproteobacteria,2KY8S@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
WH3_k127_4227919_1	1348657.M622_04865	8.423e-54	189.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VNSH@28216|Betaproteobacteria,2KYPA@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
WH3_k127_4234149_3	1479239.JQMU01000001_gene1621	6.536e-80	267.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
WH3_k127_4234149_2	1479239.JQMU01000001_gene1620	4.095e-86	286.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2K4B2@204457|Sphingomonadales	204457|Sphingomonadales	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WH3_k127_4234149_0	1248916.ANFY01000007_gene2178	0.0	1001.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2TTXG@28211|Alphaproteobacteria,2K1IU@204457|Sphingomonadales	204457|Sphingomonadales	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
WH3_k127_4234149_6	1282876.BAOK01000001_gene1821	5.589e-08	60.0	2DNQ5@1|root,32YJ0@2|Bacteria,1NAFP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4234149_1	1248916.ANFY01000007_gene2175	3.719e-185	584.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2U0BA@28211|Alphaproteobacteria,2K2ZH@204457|Sphingomonadales	204457|Sphingomonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WH3_k127_4234149_5	344747.PM8797T_16288	3.967e-10	74.0	COG2319@1|root,COG2319@2|Bacteria,2J48X@203682|Planctomycetes	203682|Planctomycetes	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
WH3_k127_4234149_4	1479238.JQMZ01000001_gene2571	1.991e-54	213.0	COG4995@1|root,COG4995@2|Bacteria,1QUP3@1224|Proteobacteria,2TW2P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
WH3_k127_4271387_0	1248917.ANFX01000019_gene2413	0.0	1504.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,2JZWE@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WH3_k127_4281531_2	1248917.ANFX01000008_gene318	7.952e-88	294.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria,2K18A@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WH3_k127_4281531_0	1479239.JQMU01000001_gene2661	4.698e-214	677.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,2K10A@204457|Sphingomonadales	204457|Sphingomonadales	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WH3_k127_4281531_1	1479239.JQMU01000001_gene2662	2.166e-128	413.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,2K2AP@204457|Sphingomonadales	204457|Sphingomonadales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WH3_k127_4305812_0	1479239.JQMU01000001_gene1878	1.071e-312	961.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUBW@28211|Alphaproteobacteria,2K2WB@204457|Sphingomonadales	204457|Sphingomonadales	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WH3_k127_4305812_3	1545915.JROG01000004_gene1746	1.729e-40	153.0	COG3791@1|root,COG3791@2|Bacteria,1N6S5@1224|Proteobacteria,2UB03@28211|Alphaproteobacteria,2K540@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
WH3_k127_4305812_2	1479239.JQMU01000001_gene1877	6.958e-54	192.0	COG3602@1|root,COG3602@2|Bacteria,1MZKQ@1224|Proteobacteria,2UG86@28211|Alphaproteobacteria,2K7EX@204457|Sphingomonadales	204457|Sphingomonadales	S	ACT domain	-	-	-	ko:K09964	-	-	-	-	ko00000	-	-	-	ACT_3,ACT_7
WH3_k127_4305812_1	1479239.JQMU01000001_gene1876	6.685e-120	387.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2K0UP@204457|Sphingomonadales	204457|Sphingomonadales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
WH3_k127_4367350_1	1479239.JQMU01000001_gene547	5.276e-224	702.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VFCG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WH3_k127_4367350_3	1479239.JQMU01000001_gene546	1.11e-54	201.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2UBTC@28211|Alphaproteobacteria,2K5XU@204457|Sphingomonadales	204457|Sphingomonadales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
WH3_k127_4367350_0	1479239.JQMU01000001_gene545	3.175e-261	806.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,2K0AN@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
WH3_k127_4367350_2	1479239.JQMU01000001_gene544	3.623e-71	241.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K0PR@204457|Sphingomonadales	204457|Sphingomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
WH3_k127_4376215_2	1479239.JQMU01000001_gene2823	1.233e-70	240.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K0FQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_4376215_1	1479239.JQMU01000001_gene2825	6.303e-78	278.0	COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,2K42W@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
WH3_k127_4376215_0	1479239.JQMU01000001_gene2826	1.137e-167	529.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,2K0RX@204457|Sphingomonadales	204457|Sphingomonadales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WH3_k127_4411844_1	1549858.MC45_03530	1.207e-58	206.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,2K17I@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
WH3_k127_4411844_3	1479239.JQMU01000001_gene556	3.099e-38	147.0	2AJXS@1|root,31AKX@2|Bacteria,1NKP1@1224|Proteobacteria,2UN6H@28211|Alphaproteobacteria,2K7WS@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4411844_0	1479239.JQMU01000001_gene555	1.831e-158	507.0	COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,2K0Z3@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell Wall	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
WH3_k127_4411844_2	1479239.JQMU01000001_gene554	5.711e-54	194.0	COG0614@1|root,COG0614@2|Bacteria,1RAUP@1224|Proteobacteria,2TUB0@28211|Alphaproteobacteria,2K23T@204457|Sphingomonadales	204457|Sphingomonadales	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WH3_k127_4466735_2	1248917.ANFX01000012_gene1817	1.977e-248	773.0	COG0591@1|root,COG4251@1|root,COG0591@2|Bacteria,COG4251@2|Bacteria,1QTSW@1224|Proteobacteria,2TW0C@28211|Alphaproteobacteria,2K0PA@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
WH3_k127_4466735_8	391600.ABRU01000040_gene1701	3.999e-56	205.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,2KGJ6@204458|Caulobacterales	204458|Caulobacterales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH3_k127_4466735_0	1248917.ANFX01000012_gene1815	0.0	1252.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,2K0M5@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WH3_k127_4466735_3	1248917.ANFX01000012_gene1814	1.165e-240	751.0	COG3203@1|root,COG3203@2|Bacteria,1MX4Q@1224|Proteobacteria,2TUSU@28211|Alphaproteobacteria,2K1P5@204457|Sphingomonadales	204457|Sphingomonadales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
WH3_k127_4466735_7	1479239.JQMU01000001_gene2222	1.664e-126	406.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria,2K0T5@204457|Sphingomonadales	204457|Sphingomonadales	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
WH3_k127_4466735_11	1479239.JQMU01000001_gene2222	0.0005621	42.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria,2K0T5@204457|Sphingomonadales	204457|Sphingomonadales	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
WH3_k127_4466735_6	1479239.JQMU01000001_gene2221	2.332e-130	420.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U36S@28211|Alphaproteobacteria,2K85U@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
WH3_k127_4466735_1	1479239.JQMU01000001_gene2220	0.0	1096.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,2K1TD@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
WH3_k127_4466735_5	1122970.AUHC01000007_gene1729	4.787e-142	454.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2TRGW@28211|Alphaproteobacteria,2K220@204457|Sphingomonadales	204457|Sphingomonadales	C	Peptidase S41	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
WH3_k127_4466735_4	1479239.JQMU01000001_gene2217	6.663e-165	522.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,2K23A@204457|Sphingomonadales	204457|Sphingomonadales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3,FixP_N
WH3_k127_4466735_10	525897.Dbac_0715	9.916e-20	96.0	COG0745@1|root,COG0745@2|Bacteria,1P3RJ@1224|Proteobacteria,431AU@68525|delta/epsilon subdivisions,2WWYD@28221|Deltaproteobacteria,2MD4K@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH3_k127_4470156_0	1248760.ANFZ01000014_gene2102	2.012e-320	985.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,2K0KY@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WH3_k127_44982_0	1479239.JQMU01000001_gene2032	4.532e-293	908.0	COG2710@1|root,COG2710@2|Bacteria,1MUGI@1224|Proteobacteria,2TU7U@28211|Alphaproteobacteria,2K1QU@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitrogenase component 1 type Oxidoreductase	-	-	1.3.7.14,1.3.7.15	ko:K11334	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro
WH3_k127_44982_2	1044.EH31_08750	4.565e-198	619.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria,2K0NE@204457|Sphingomonadales	204457|Sphingomonadales	D	Belongs to the NifH BchL ChlL family	-	-	1.3.7.14,1.3.7.15	ko:K11333	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000	-	-	-	Fer4_NifH
WH3_k127_44982_3	1479239.JQMU01000001_gene2034	2.32e-196	614.0	COG1063@1|root,COG1063@2|Bacteria,1MVZC@1224|Proteobacteria,2TRM6@28211|Alphaproteobacteria,2JZWZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Dehydrogenase	-	-	1.1.1.396	ko:K11337	ko00860,ko01110,map00860,map01110	-	R09055	RC01377	ko00000,ko00001,ko01000	-	-	-	ADH_N
WH3_k127_44982_1	1479239.JQMU01000001_gene2035	5.507e-205	641.0	COG0500@1|root,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,2TSZC@28211|Alphaproteobacteria,2K0Z5@204457|Sphingomonadales	204457|Sphingomonadales	Q	O-methyltransferase	-	-	2.1.1.210	ko:K09846	ko00906,ko01100,map00906,map01100	-	R07521,R07524,R07527,R07529,R07533,R07535	RC00003,RC02082	ko00000,ko00001,ko01000	-	-	-	Dimerisation2,Methyltransf_2
WH3_k127_44982_4	1122970.AUHC01000004_gene2281	1.408e-49	181.0	COG1233@1|root,COG1233@2|Bacteria,1MX1C@1224|Proteobacteria,2TS2R@28211|Alphaproteobacteria,2K0TG@204457|Sphingomonadales	204457|Sphingomonadales	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.27	ko:K09845	ko00906,ko01100,map00906,map01100	-	R07517,R07520,R07523,R07534	RC02080	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WH3_k127_4500082_3	1248917.ANFX01000051_gene443	1.656e-52	190.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,2K1X7@204457|Sphingomonadales	204457|Sphingomonadales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
WH3_k127_4500082_1	1479239.JQMU01000001_gene2097	1.662e-111	369.0	COG2740@1|root,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,2U9RY@28211|Alphaproteobacteria,2K2B7@204457|Sphingomonadales	204457|Sphingomonadales	K	Nucleic-acid-binding protein	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
WH3_k127_4500082_0	1248917.ANFX01000051_gene445	8e-323	994.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,2K1KF@204457|Sphingomonadales	204457|Sphingomonadales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
WH3_k127_4500082_2	1248917.ANFX01000051_gene446	1.733e-100	329.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,2K45N@204457|Sphingomonadales	204457|Sphingomonadales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
WH3_k127_4500082_4	1479239.JQMU01000001_gene2094	3.167e-39	151.0	2AQGV@1|root,31FPD@2|Bacteria,1P7MW@1224|Proteobacteria,2UYPE@28211|Alphaproteobacteria,2K84E@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WH3_k127_4500082_5	1479239.JQMU01000001_gene2093	8.132e-15	77.0	2AKDR@1|root,31B50@2|Bacteria,1Q6WN@1224|Proteobacteria,2VCZU@28211|Alphaproteobacteria,2KC3M@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4501528_3	1479239.JQMU01000001_gene1386	1.373e-148	476.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2TUSP@28211|Alphaproteobacteria,2K22Y@204457|Sphingomonadales	204457|Sphingomonadales	D	Membrane-bound metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WH3_k127_4501528_0	1479239.JQMU01000001_gene1385	2.528e-261	809.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,2K0TK@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WH3_k127_4501528_6	1479239.JQMU01000001_gene1384	6.911e-84	279.0	COG1495@1|root,COG1495@2|Bacteria,1N89I@1224|Proteobacteria,2UF49@28211|Alphaproteobacteria,2K59V@204457|Sphingomonadales	204457|Sphingomonadales	O	Disulfide bond formation protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbB
WH3_k127_4501528_4	1479239.JQMU01000001_gene1383	1.007e-98	325.0	COG2941@1|root,COG2941@2|Bacteria,1RAK4@1224|Proteobacteria,2U85I@28211|Alphaproteobacteria,2K46W@204457|Sphingomonadales	204457|Sphingomonadales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
WH3_k127_4501528_1	1479239.JQMU01000001_gene1382	2e-236	735.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2TR5F@28211|Alphaproteobacteria,2K04J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH3_k127_4501528_5	1479239.JQMU01000001_gene1381	7.634e-88	299.0	2BJB4@1|root,32DM3@2|Bacteria,1N0RM@1224|Proteobacteria,2UA4A@28211|Alphaproteobacteria,2K51P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4501528_2	1479239.JQMU01000001_gene1380	2.711e-172	541.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2TSIP@28211|Alphaproteobacteria,2K0VH@204457|Sphingomonadales	204457|Sphingomonadales	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WH3_k127_4504403_2	1479239.JQMU01000001_gene1176	2.214e-158	500.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2K093@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_4504403_0	1479239.JQMU01000001_gene1177	2.543e-246	762.0	COG1804@1|root,COG1804@2|Bacteria,1R43P@1224|Proteobacteria,2U1WN@28211|Alphaproteobacteria,2K3HJ@204457|Sphingomonadales	204457|Sphingomonadales	C	carnitine dehydratase	-	-	5.4.1.3	ko:K14470	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09283	RC02480	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
WH3_k127_4504403_1	1248917.ANFX01000013_gene1461	3.447e-244	756.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K04I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_4504403_3	1248917.ANFX01000013_gene1462	4.945e-50	180.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2TV0U@28211|Alphaproteobacteria,2K2J9@204457|Sphingomonadales	204457|Sphingomonadales	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153	ko:K09709	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09282	RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
WH3_k127_4514559_2	1044.EH31_03905	2.635e-55	199.0	2DI70@1|root,30276@2|Bacteria,1RKFN@1224|Proteobacteria,2UB2C@28211|Alphaproteobacteria,2K5M2@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4514559_0	1479239.JQMU01000001_gene2128	9.788e-193	606.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2TSVJ@28211|Alphaproteobacteria,2K0F0@204457|Sphingomonadales	204457|Sphingomonadales	P	COG0798 Arsenite efflux pump ACR3 and related permeases	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WH3_k127_4514559_1	1479239.JQMU01000001_gene604	6.949e-96	317.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2U2F2@28211|Alphaproteobacteria,2K1M3@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
WH3_k127_4514559_3	1121035.AUCH01000001_gene1791	1.954e-39	154.0	COG0642@1|root,COG2770@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVVC@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0642 Signal transduction histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
WH3_k127_4521545_11	1479239.JQMU01000001_gene2837	4.577e-11	64.0	COG4076@1|root,COG4076@2|Bacteria,1QU4H@1224|Proteobacteria,2TVZ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4521545_6	1248917.ANFX01000031_gene2549	2.598e-117	380.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria,2K411@204457|Sphingomonadales	204457|Sphingomonadales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
WH3_k127_4521545_3	1522072.IL54_1004	2.19e-218	712.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,2K00N@204457|Sphingomonadales	204457|Sphingomonadales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
WH3_k127_4521545_10	1038866.KB902835_gene576	1.324e-11	77.0	2BT1Y@1|root,32N69@2|Bacteria,1R9BE@1224|Proteobacteria,2U1H7@28211|Alphaproteobacteria,3JWFK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4521545_4	1479239.JQMU01000001_gene2833	2.07e-143	459.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,2K2BU@204457|Sphingomonadales	204457|Sphingomonadales	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
WH3_k127_4521545_0	1479239.JQMU01000001_gene2832	0.0	1481.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,2K0P9@204457|Sphingomonadales	204457|Sphingomonadales	M	Penicillin-binding Protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
WH3_k127_4521545_8	1479239.JQMU01000001_gene2831	1.187e-81	274.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2U9FF@28211|Alphaproteobacteria,2K56N@204457|Sphingomonadales	204457|Sphingomonadales	O	Peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WH3_k127_4521545_2	1479239.JQMU01000001_gene2830	5.717e-229	712.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,2K0B2@204457|Sphingomonadales	204457|Sphingomonadales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WH3_k127_4521545_5	1479239.JQMU01000001_gene2829	2.111e-131	422.0	COG4798@1|root,COG4798@2|Bacteria,1QUNP@1224|Proteobacteria,2TW23@28211|Alphaproteobacteria,2KE94@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
WH3_k127_4521545_1	1479239.JQMU01000001_gene2828	3.421e-300	927.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2TV8B@28211|Alphaproteobacteria,2K00A@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
WH3_k127_4521545_7	1248917.ANFX01000031_gene2557	2.414e-107	354.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2URCQ@28211|Alphaproteobacteria,2K511@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0227
WH3_k127_4521545_9	1479239.JQMU01000001_gene2826	9.605e-46	165.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,2K0RX@204457|Sphingomonadales	204457|Sphingomonadales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WH3_k127_4522951_5	1479239.JQMU01000001_gene936	5.633e-116	378.0	COG3239@1|root,COG3239@2|Bacteria,1MVY5@1224|Proteobacteria,2U156@28211|Alphaproteobacteria,2K0CR@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
WH3_k127_4522951_1	1479239.JQMU01000001_gene937	1.337e-223	696.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,2TUU2@28211|Alphaproteobacteria,2K0BS@204457|Sphingomonadales	204457|Sphingomonadales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4522951_4	1479239.JQMU01000001_gene938	1.012e-121	395.0	COG0784@1|root,COG0784@2|Bacteria,1MX3Y@1224|Proteobacteria,2TT2R@28211|Alphaproteobacteria,2K0S1@204457|Sphingomonadales	204457|Sphingomonadales	T	In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma70_r4_2
WH3_k127_4522951_0	1479239.JQMU01000001_gene939	1.85e-315	973.0	COG3614@1|root,COG3920@1|root,COG3614@2|Bacteria,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria,2U4QM@28211|Alphaproteobacteria,2K26R@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HWE_HK
WH3_k127_4522951_8	1479239.JQMU01000001_gene940	4.376e-25	109.0	2AJ4M@1|root,319P5@2|Bacteria,1Q3E2@1224|Proteobacteria,2VA9G@28211|Alphaproteobacteria,2KC2N@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4522951_7	1122970.AUHC01000013_gene1049	1.263e-111	363.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TUUZ@28211|Alphaproteobacteria,2K0TM@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_4522951_6	1248917.ANFX01000014_gene1379	1.869e-112	364.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2U7B1@28211|Alphaproteobacteria,2K410@204457|Sphingomonadales	204457|Sphingomonadales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
WH3_k127_4522951_2	1248917.ANFX01000014_gene1378	7.775e-196	622.0	COG1301@1|root,COG1301@2|Bacteria,1MVID@1224|Proteobacteria,2TUR0@28211|Alphaproteobacteria,2K09V@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
WH3_k127_4522951_3	1248917.ANFX01000014_gene1377	8.466e-154	488.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JZV4@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WH3_k127_4523389_5	1479239.JQMU01000001_gene889	5.133e-25	107.0	29W6D@1|root,30HRG@2|Bacteria,1MVGF@1224|Proteobacteria,2U205@28211|Alphaproteobacteria,2K35K@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4523389_4	1479239.JQMU01000001_gene1039	2.254e-73	251.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,2K57H@204457|Sphingomonadales	204457|Sphingomonadales	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
WH3_k127_4523389_0	1122970.AUHC01000002_gene1393	7.31e-171	540.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2K0V3@204457|Sphingomonadales	204457|Sphingomonadales	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WH3_k127_4523389_1	1479239.JQMU01000001_gene1041	2.313e-151	483.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,2U5HN@28211|Alphaproteobacteria,2K2C2@204457|Sphingomonadales	204457|Sphingomonadales	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WH3_k127_4523389_3	1479239.JQMU01000001_gene1042	9.192e-116	378.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,2K0CZ@204457|Sphingomonadales	204457|Sphingomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WH3_k127_4523389_2	1479239.JQMU01000001_gene1043	2.617e-137	437.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2TSIA@28211|Alphaproteobacteria,2K0U7@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
WH3_k127_4539532_0	1479239.JQMU01000001_gene570	3.04e-171	548.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2TTG4@28211|Alphaproteobacteria,2K1ZW@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WH3_k127_4539532_3	1479239.JQMU01000001_gene569	2.141e-74	255.0	2AIXJ@1|root,319F7@2|Bacteria,1NNE0@1224|Proteobacteria,2UKDH@28211|Alphaproteobacteria,2KA75@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4539532_2	1479239.JQMU01000001_gene568	6.138e-101	335.0	2AHF3@1|root,317SD@2|Bacteria,1NATF@1224|Proteobacteria,2UU7B@28211|Alphaproteobacteria,2K732@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4539532_1	1248917.ANFX01000047_gene1608	1.011e-111	363.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2U6ZM@28211|Alphaproteobacteria,2K16N@204457|Sphingomonadales	204457|Sphingomonadales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
WH3_k127_4559359_0	1479239.JQMU01000001_gene550	1.624e-174	547.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,2K0VM@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WH3_k127_4566740_6	1479239.JQMU01000001_gene883	8.239e-51	181.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2U2ZG@28211|Alphaproteobacteria,2K2FX@204457|Sphingomonadales	204457|Sphingomonadales	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
WH3_k127_4566740_5	1122137.AQXF01000004_gene1561	2.49e-66	230.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
WH3_k127_4566740_10	1122137.AQXF01000004_gene1562	1.608e-37	143.0	COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2UBV0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2282
WH3_k127_4566740_3	1248916.ANFY01000007_gene2542	6.746e-109	359.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2TRZJ@28211|Alphaproteobacteria,2K1E6@204457|Sphingomonadales	28211|Alphaproteobacteria	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
WH3_k127_4566740_9	1122137.AQXF01000004_gene1564	1.042e-38	155.0	COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,2TTIN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
WH3_k127_4566740_7	1248916.ANFY01000007_gene2544	4.374e-50	182.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2TVZ9@28211|Alphaproteobacteria,2K5X8@204457|Sphingomonadales	204457|Sphingomonadales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
WH3_k127_4566740_2	1248916.ANFY01000007_gene2557	1.708e-114	372.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2U5BS@28211|Alphaproteobacteria,2K4S9@204457|Sphingomonadales	204457|Sphingomonadales	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WH3_k127_4566740_8	693977.Deipr_1715	1.273e-43	166.0	2C312@1|root,2Z7N1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4566740_11	426355.Mrad2831_4683	5.074e-07	56.0	2AAUY@1|root,3107T@2|Bacteria,1PN80@1224|Proteobacteria,2V2EG@28211|Alphaproteobacteria,1JYFF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4566740_1	1248916.ANFY01000007_gene2545	5.759e-136	437.0	COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,2VEUG@28211|Alphaproteobacteria,2KDUI@204457|Sphingomonadales	204457|Sphingomonadales	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WH3_k127_4566740_4	1248916.ANFY01000007_gene2547	1.852e-99	328.0	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,2VEUH@28211|Alphaproteobacteria,2K4BN@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
WH3_k127_4566740_0	1248916.ANFY01000007_gene2548	3.518e-162	524.0	COG1018@1|root,COG3576@1|root,COG1018@2|Bacteria,COG3576@2|Bacteria,1MV41@1224|Proteobacteria,2TQXP@28211|Alphaproteobacteria,2K2UG@204457|Sphingomonadales	204457|Sphingomonadales	C	Oxidoreductase FAD-binding domain	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1,Putative_PNPOx
WH3_k127_4584733_1	1479239.JQMU01000001_gene544	2.471e-128	417.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K0PR@204457|Sphingomonadales	204457|Sphingomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
WH3_k127_4584733_2	237727.NAP1_07090	3.082e-63	223.0	2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,2U9KI@28211|Alphaproteobacteria,2K5WE@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WH3_k127_4584733_0	1479239.JQMU01000001_gene543	6.094e-138	442.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2TS40@28211|Alphaproteobacteria,2K206@204457|Sphingomonadales	204457|Sphingomonadales	S	COG2041 Sulfite oxidase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
WH3_k127_4584733_3	1122970.AUHC01000005_gene1962	9.785e-12	66.0	COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2U0ZF@28211|Alphaproteobacteria,2K0DE@204457|Sphingomonadales	204457|Sphingomonadales	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WH3_k127_4590971_0	1479239.JQMU01000001_gene893	0.0	1011.0	COG0758@1|root,COG0758@2|Bacteria,1R9P1@1224|Proteobacteria,2U30Q@28211|Alphaproteobacteria,2K3JF@204457|Sphingomonadales	204457|Sphingomonadales	LU	DNA mediated transformation	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4590971_2	1479239.JQMU01000001_gene894	2.721e-167	553.0	COG0790@1|root,COG5640@1|root,COG0790@2|Bacteria,COG5640@2|Bacteria,1NFNT@1224|Proteobacteria,2U9RV@28211|Alphaproteobacteria,2K755@204457|Sphingomonadales	204457|Sphingomonadales	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
WH3_k127_4590971_1	1479239.JQMU01000001_gene896	1.188e-314	974.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1N7YB@1224|Proteobacteria,2V7CZ@28211|Alphaproteobacteria,2K2SU@204457|Sphingomonadales	204457|Sphingomonadales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
WH3_k127_4590971_4	1479239.JQMU01000001_gene1619	2.5e-60	209.0	COG1320@1|root,COG1320@2|Bacteria,1MZ6Z@1224|Proteobacteria,2UD2X@28211|Alphaproteobacteria,2K4GK@204457|Sphingomonadales	204457|Sphingomonadales	P	Na+/H+ antiporter subunit	phaG	-	-	ko:K05564	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	PhaG_MnhG_YufB
WH3_k127_4598664_4	1248917.ANFX01000037_gene2137	2.822e-93	306.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,2K0GM@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
WH3_k127_4598664_6	1122970.AUHC01000009_gene299	3.982e-45	164.0	2C7TH@1|root,32RJS@2|Bacteria,1MZK8@1224|Proteobacteria,2UC2R@28211|Alphaproteobacteria,2K5XZ@204457|Sphingomonadales	204457|Sphingomonadales	S	ETC complex I subunit	-	-	-	-	-	-	-	-	-	-	-	-	ETC_C1_NDUFA4
WH3_k127_4598664_1	1479239.JQMU01000001_gene497	2.583e-317	978.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,2K0MV@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
WH3_k127_4598664_5	383381.EH30_03375	7.369e-56	201.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,2K5JW@204457|Sphingomonadales	204457|Sphingomonadales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
WH3_k127_4598664_0	1248917.ANFX01000037_gene2145	0.0	1427.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,2K15B@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WH3_k127_4598664_7	1479239.JQMU01000001_gene493	1.993e-44	165.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria,2K5WD@204457|Sphingomonadales	204457|Sphingomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WH3_k127_4598664_3	1479239.JQMU01000001_gene492	4.177e-128	421.0	2D5TK@1|root,32TJS@2|Bacteria,1RGDJ@1224|Proteobacteria,2U915@28211|Alphaproteobacteria,2K4D6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4598664_2	383381.EH30_03395	9.096e-138	444.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria,2K163@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
WH3_k127_4605696_0	1479239.JQMU01000001_gene2865	1.647e-278	857.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2TS0R@28211|Alphaproteobacteria,2K0PG@204457|Sphingomonadales	204457|Sphingomonadales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
WH3_k127_4605696_2	1549858.MC45_00775	4.99e-19	97.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2UPFA@28211|Alphaproteobacteria,2KE1Y@204457|Sphingomonadales	204457|Sphingomonadales	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WH3_k127_4605696_1	1479239.JQMU01000001_gene2867	3.205e-275	852.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2U35U@28211|Alphaproteobacteria,2K136@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WH3_k127_4620929_1	1479239.JQMU01000001_gene2606	4.604e-97	319.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,2K1S1@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
WH3_k127_4620929_2	1122970.AUHC01000001_gene387	8.403e-56	199.0	2AMEP@1|root,31CA4@2|Bacteria,1Q8AU@1224|Proteobacteria,2VEGW@28211|Alphaproteobacteria,2KB1M@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4620929_0	383381.EH30_05405	1.323e-186	584.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,2K18M@204457|Sphingomonadales	204457|Sphingomonadales	C	Dehydrogenase	-	-	1.1.2.3,1.1.99.31	ko:K00101,ko:K15054	ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120	-	R00196,R04160,R07664	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
WH3_k127_4648876_3	1479239.JQMU01000001_gene364	1.666e-68	235.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,2K0BP@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WH3_k127_4648876_2	1248917.ANFX01000041_gene1736	1.908e-133	430.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,2K1X9@204457|Sphingomonadales	204457|Sphingomonadales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WH3_k127_4648876_0	1479239.JQMU01000001_gene367	3.696e-258	797.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,2K08Q@204457|Sphingomonadales	204457|Sphingomonadales	E	5-aminolevulinic acid synthase	-	-	2.3.1.37	ko:K00643	ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110	-	R00830	RC00004,RC02815	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_4648876_1	1479239.JQMU01000001_gene368	7.031e-144	458.0	COG0778@1|root,COG0778@2|Bacteria,1MWMJ@1224|Proteobacteria,2TU8B@28211|Alphaproteobacteria,2K1M9@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WH3_k127_4648876_4	1248916.ANFY01000006_gene1972	1.069e-27	117.0	COG5622@1|root,COG5622@2|Bacteria,1RIEJ@1224|Proteobacteria,2U7UE@28211|Alphaproteobacteria,2K400@204457|Sphingomonadales	204457|Sphingomonadales	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
WH3_k127_4648876_5	383381.EH30_04670	4.111e-23	101.0	COG3658@1|root,COG3658@2|Bacteria,1RF4V@1224|Proteobacteria,2U6ZE@28211|Alphaproteobacteria,2K52I@204457|Sphingomonadales	204457|Sphingomonadales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WH3_k127_4666672_1	1479239.JQMU01000001_gene2170	7.899e-74	251.0	2C2J5@1|root,315UG@2|Bacteria,1RHAH@1224|Proteobacteria,2U94W@28211|Alphaproteobacteria,2K4E5@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF3576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3576
WH3_k127_4666672_0	1248917.ANFX01000013_gene1480	0.0	1088.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,2K0Q0@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WH3_k127_4670926_1	1248917.ANFX01000016_gene2440	2.877e-40	151.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2K5T1@204457|Sphingomonadales	204457|Sphingomonadales	E	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH3_k127_4670926_0	1479239.JQMU01000001_gene2046	6.774e-193	605.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2TR6P@28211|Alphaproteobacteria,2K8UY@204457|Sphingomonadales	204457|Sphingomonadales	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
WH3_k127_4747556_1	1122970.AUHC01000004_gene2211	1.518e-176	560.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,2K39Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
WH3_k127_4747556_0	1122970.AUHC01000004_gene2212	5.432e-199	623.0	2DB8I@1|root,2Z7RY@2|Bacteria,1MY4M@1224|Proteobacteria,2U2A8@28211|Alphaproteobacteria,2K1YC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4760104_2	517722.AEUE01000007_gene265	2.015e-79	270.0	COG0584@1|root,COG0584@2|Bacteria,1MYB7@1224|Proteobacteria,2UA5S@28211|Alphaproteobacteria,2K8DA@204457|Sphingomonadales	204457|Sphingomonadales	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
WH3_k127_4760104_1	1479239.JQMU01000001_gene180	1.387e-173	547.0	COG1073@1|root,COG1073@2|Bacteria,1QUNS@1224|Proteobacteria,2TW26@28211|Alphaproteobacteria,2K2SZ@204457|Sphingomonadales	204457|Sphingomonadales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	3.1.1.76	ko:K22250	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
WH3_k127_4760104_0	1479239.JQMU01000001_gene179	6.791e-215	668.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TVC3@28211|Alphaproteobacteria,2K3AC@204457|Sphingomonadales	204457|Sphingomonadales	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
WH3_k127_4820651_1	1248917.ANFX01000008_gene421	5.512e-84	280.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,2K0JN@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WH3_k127_4820651_0	1248917.ANFX01000008_gene422	8.888e-202	630.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,2K0GC@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WH3_k127_4886251_1	1248917.ANFX01000029_gene2643	7.101e-63	218.0	COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,2K4K6@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
WH3_k127_4886251_0	1479239.JQMU01000001_gene1870	4.181e-112	373.0	2CXIK@1|root,32T23@2|Bacteria,1R8AW@1224|Proteobacteria,2U1NN@28211|Alphaproteobacteria,2K2FG@204457|Sphingomonadales	204457|Sphingomonadales	S	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
WH3_k127_4912426_4	1248917.ANFX01000029_gene2627	2.038e-46	167.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2TRXJ@28211|Alphaproteobacteria,2K28T@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WH3_k127_4912426_2	1234595.C725_0645	3.163e-128	428.0	2C59N@1|root,32TAY@2|Bacteria,1R669@1224|Proteobacteria,2U2IK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4912426_0	1248917.ANFX01000029_gene2624	3.545e-234	726.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2TT2F@28211|Alphaproteobacteria,2K0I7@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH flavin	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
WH3_k127_4912426_1	1248917.ANFX01000029_gene2623	5.947e-164	518.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2K1CY@204457|Sphingomonadales	204457|Sphingomonadales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH3_k127_4912426_3	1479239.JQMU01000001_gene1907	1.732e-116	375.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,2K13Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
WH3_k127_4922423_1	1122970.AUHC01000002_gene1193	6.063e-56	196.0	COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,2TT68@28211|Alphaproteobacteria,2K2GA@204457|Sphingomonadales	204457|Sphingomonadales	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH3_k127_4922423_2	237727.NAP1_12218	1.377e-31	129.0	2CM6U@1|root,2ZRQ1@2|Bacteria,1NDYF@1224|Proteobacteria,2UHHI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_4922423_0	1479239.JQMU01000001_gene1312	8.731e-66	229.0	COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2UD2M@28211|Alphaproteobacteria,2K56H@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
WH3_k127_4922423_3	1479239.JQMU01000001_gene1311	1.474e-26	113.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2U8YK@28211|Alphaproteobacteria,2KD5N@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WH3_k127_4922423_4	378806.STAUR_3085	1.305e-09	66.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1REF1@1224|Proteobacteria,42Q4N@68525|delta/epsilon subdivisions,2WS51@28221|Deltaproteobacteria,2YWNR@29|Myxococcales	28221|Deltaproteobacteria	O	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6,Peptidase_S8
WH3_k127_4932758_1	1479239.JQMU01000001_gene839	5.025e-149	474.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2K0GT@204457|Sphingomonadales	204457|Sphingomonadales	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WH3_k127_4932758_0	1248917.ANFX01000020_gene2254	1.984e-165	522.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2TS3H@28211|Alphaproteobacteria,2K055@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
WH3_k127_4951553_2	685035.ADAE01000018_gene565	1.083e-73	250.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2K03C@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WH3_k127_4951553_1	314225.ELI_05365	6.421e-77	265.0	COG4544@1|root,COG4544@2|Bacteria,1MY56@1224|Proteobacteria,2U9Y7@28211|Alphaproteobacteria,2K4KW@204457|Sphingomonadales	204457|Sphingomonadales	S	SOS response	-	-	-	ko:K14160	-	-	-	-	ko00000,ko03400	-	-	-	-
WH3_k127_4951553_0	1479239.JQMU01000001_gene2587	3.345e-276	858.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,2JZYV@204457|Sphingomonadales	204457|Sphingomonadales	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
WH3_k127_4951553_3	1479239.JQMU01000001_gene2588	2.237e-45	171.0	2ABIZ@1|root,3110A@2|Bacteria,1PP1G@1224|Proteobacteria,2V1JP@28211|Alphaproteobacteria,2KB22@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WH3_k127_4968526_1	1479239.JQMU01000001_gene2752	1.854e-214	669.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,2K01N@204457|Sphingomonadales	204457|Sphingomonadales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
WH3_k127_4968526_0	1479239.JQMU01000001_gene2751	4.182e-278	857.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,2K1KM@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH3_k127_4968526_2	1479239.JQMU01000001_gene2750	1.549e-94	315.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,2K2YT@204457|Sphingomonadales	204457|Sphingomonadales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
WH3_k127_4968526_3	383381.EH30_06165	1.434e-73	249.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria,2K0SI@204457|Sphingomonadales	204457|Sphingomonadales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WH3_k127_497546_0	1479239.JQMU01000001_gene2173	3.654e-88	300.0	COG2197@1|root,COG2197@2|Bacteria,1RHWP@1224|Proteobacteria,2UA0I@28211|Alphaproteobacteria,2K0NR@204457|Sphingomonadales	204457|Sphingomonadales	KT	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019,GerE
WH3_k127_497546_2	1122970.AUHC01000010_gene1662	2.09e-34	132.0	COG4321@1|root,COG4321@2|Bacteria,1PSCA@1224|Proteobacteria,2VA8Q@28211|Alphaproteobacteria,2K6W1@204457|Sphingomonadales	204457|Sphingomonadales	S	protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	RHH_4
WH3_k127_497546_1	1248917.ANFX01000013_gene1517	2.586e-44	163.0	2AMQC@1|root,31CKJ@2|Bacteria,1P29J@1224|Proteobacteria,2UUNC@28211|Alphaproteobacteria,2KB8M@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_498853_1	1248917.ANFX01000019_gene2417	2.912e-79	271.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria,2K0M4@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX2	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WH3_k127_498853_2	1479239.JQMU01000001_gene1080	5.576e-67	231.0	2C2D1@1|root,3056B@2|Bacteria,1NN2W@1224|Proteobacteria,2UMK4@28211|Alphaproteobacteria,2K85A@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_498853_0	1248917.ANFX01000019_gene2414	0.0	1016.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,2K1CM@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WH3_k127_5001766_0	1479239.JQMU01000001_gene159	3.498e-153	487.0	COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,2TUQA@28211|Alphaproteobacteria,2K2PT@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C13
WH3_k127_5001766_1	1121123.AUAO01000002_gene88	2.696e-43	168.0	COG0652@1|root,COG0652@2|Bacteria,1RGF5@1224|Proteobacteria,2U980@28211|Alphaproteobacteria,2KGP8@204458|Caulobacterales	204458|Caulobacterales	M	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
WH3_k127_5029241_3	1479239.JQMU01000001_gene798	1.068e-63	220.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,2K19Y@204457|Sphingomonadales	204457|Sphingomonadales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
WH3_k127_5029241_1	1479239.JQMU01000001_gene797	3.604e-101	336.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,2UMED@28211|Alphaproteobacteria,2K52Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
WH3_k127_5029241_0	1479239.JQMU01000001_gene796	2.321e-132	433.0	291EX@1|root,2ZP1S@2|Bacteria,1RF3T@1224|Proteobacteria,2U83Z@28211|Alphaproteobacteria,2K4S8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mitofilin
WH3_k127_5029241_2	1479239.JQMU01000001_gene795	6.265e-85	282.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,2JZY3@204457|Sphingomonadales	204457|Sphingomonadales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
WH3_k127_5030464_0	1122970.AUHC01000009_gene325	9.344e-195	608.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2K11Z@204457|Sphingomonadales	204457|Sphingomonadales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WH3_k127_5030464_1	1248917.ANFX01000037_gene2108	5.943e-173	544.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2TQT2@28211|Alphaproteobacteria,2K2TX@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH3_k127_503921_13	1248917.ANFX01000014_gene1361	1.412e-93	312.0	COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,2TX7R@28211|Alphaproteobacteria,2K4HR@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
WH3_k127_503921_7	1479239.JQMU01000001_gene958	1.138e-145	480.0	COG1714@1|root,COG1714@2|Bacteria,1RAZN@1224|Proteobacteria,2U6W9@28211|Alphaproteobacteria,2K24C@204457|Sphingomonadales	204457|Sphingomonadales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
WH3_k127_503921_4	1479239.JQMU01000001_gene957	6.117e-181	585.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,2U06S@28211|Alphaproteobacteria,2JZZD@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
WH3_k127_503921_0	1479239.JQMU01000001_gene956	4.691e-249	775.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,2TU87@28211|Alphaproteobacteria,2K038@204457|Sphingomonadales	204457|Sphingomonadales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WH3_k127_503921_3	1479239.JQMU01000001_gene955	4.075e-189	593.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,2K1NZ@204457|Sphingomonadales	204457|Sphingomonadales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WH3_k127_503921_2	1479239.JQMU01000001_gene954	1.278e-198	627.0	2952T@1|root,2ZSFJ@2|Bacteria,1RGF9@1224|Proteobacteria,2U83E@28211|Alphaproteobacteria,2K2TA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_503921_11	1479239.JQMU01000001_gene953	2.26e-108	355.0	2C58E@1|root,32V5I@2|Bacteria,1N13T@1224|Proteobacteria,2UBSB@28211|Alphaproteobacteria,2K675@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
WH3_k127_503921_8	314225.ELI_10290	2.748e-143	462.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2TSUT@28211|Alphaproteobacteria,2K0AM@204457|Sphingomonadales	204457|Sphingomonadales	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
WH3_k127_503921_12	1248917.ANFX01000014_gene1369	1.327e-104	345.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,2K42S@204457|Sphingomonadales	204457|Sphingomonadales	C	cytochrome C	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
WH3_k127_503921_10	1479239.JQMU01000001_gene950	2.436e-124	402.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,2K02A@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
WH3_k127_503921_1	1479239.JQMU01000001_gene949	6.87e-223	696.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,2K1HK@204457|Sphingomonadales	204457|Sphingomonadales	FP	exopolyphosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
WH3_k127_503921_5	1248917.ANFX01000014_gene1372	1.031e-173	546.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,2K00V@204457|Sphingomonadales	204457|Sphingomonadales	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WH3_k127_503921_6	1248917.ANFX01000014_gene1373	3.016e-167	536.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2TT62@28211|Alphaproteobacteria,2K24D@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
WH3_k127_503921_9	237727.NAP1_10763	1.189e-126	408.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,2K24Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase,Phos_pyr_kin
WH3_k127_5043730_0	1248917.ANFX01000019_gene2406	1.068e-245	766.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,2K152@204457|Sphingomonadales	204457|Sphingomonadales	V	Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WH3_k127_5043730_1	383381.EH30_12055	0.0008989	42.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2TR7U@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0668 Small-conductance mechanosensitive channel	mscS	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022607,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055082,GO:0055085,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
WH3_k127_5059236_5	1479239.JQMU01000001_gene1713	2.698e-60	209.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,2UA68@28211|Alphaproteobacteria,2KDMA@204457|Sphingomonadales	204457|Sphingomonadales	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
WH3_k127_5059236_4	1479239.JQMU01000001_gene1712	2.725e-67	233.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2U94I@28211|Alphaproteobacteria,2K5CH@204457|Sphingomonadales	204457|Sphingomonadales	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WH3_k127_5059236_7	1479239.JQMU01000001_gene1711	2.22e-41	154.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2U3ZF@28211|Alphaproteobacteria,2K5HS@204457|Sphingomonadales	204457|Sphingomonadales	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
WH3_k127_5059236_0	1479239.JQMU01000001_gene1710	4.059e-151	480.0	COG4786@1|root,COG4786@2|Bacteria,1NSEC@1224|Proteobacteria,2U8II@28211|Alphaproteobacteria,2KD3M@204457|Sphingomonadales	204457|Sphingomonadales	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Flg_bb_rod,Flg_bbr_C
WH3_k127_5059236_2	1479239.JQMU01000001_gene1709	4.069e-128	412.0	COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,2U8PH@28211|Alphaproteobacteria,2KD35@204457|Sphingomonadales	204457|Sphingomonadales	N	flagellar basal body	flgF	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WH3_k127_5059236_1	1122970.AUHC01000012_gene971	4.609e-145	462.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2TRR4@28211|Alphaproteobacteria,2K1WG@204457|Sphingomonadales	204457|Sphingomonadales	N	flagellar basal-body rod protein FlgG	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WH3_k127_5059236_3	1122970.AUHC01000012_gene970	1.276e-102	340.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2U8NB@28211|Alphaproteobacteria,2KD4N@204457|Sphingomonadales	204457|Sphingomonadales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
WH3_k127_5059236_6	1479239.JQMU01000001_gene1706	3.268e-46	174.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria,2K00I@204457|Sphingomonadales	204457|Sphingomonadales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
WH3_k127_5060948_4	1479239.JQMU01000001_gene1897	5.954e-55	193.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2KCVI@204457|Sphingomonadales	204457|Sphingomonadales	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WH3_k127_5060948_0	383381.EH30_00490	3.332e-299	933.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,2TVX5@28211|Alphaproteobacteria,2KE9P@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_5060948_3	1479239.JQMU01000001_gene1899	2.16e-61	213.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2U70U@28211|Alphaproteobacteria,2K5DH@204457|Sphingomonadales	204457|Sphingomonadales	P	arsenate reductase	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
WH3_k127_5060948_1	1479239.JQMU01000001_gene1900	1.069e-240	750.0	COG0477@1|root,COG0477@2|Bacteria,1QUPF@1224|Proteobacteria,2U2HA@28211|Alphaproteobacteria,2K096@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_5060948_2	1479239.JQMU01000001_gene1901	1.656e-96	320.0	2EUMT@1|root,33N3N@2|Bacteria,1N09P@1224|Proteobacteria,2UC0R@28211|Alphaproteobacteria,2KDMX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
WH3_k127_5066527_0	1479239.JQMU01000001_gene1147	2.837e-318	979.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JZZB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_5066527_2	1479239.JQMU01000001_gene1146	8.136e-177	556.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,2K1JZ@204457|Sphingomonadales	204457|Sphingomonadales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WH3_k127_5066527_1	1479239.JQMU01000001_gene1145	7.688e-248	785.0	COG1565@1|root,COG3064@1|root,COG1565@2|Bacteria,COG3064@2|Bacteria,1N3CJ@1224|Proteobacteria,2TRHW@28211|Alphaproteobacteria,2K21E@204457|Sphingomonadales	204457|Sphingomonadales	M	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	ko:K18164	ko04714,map04714	-	-	-	ko00000,ko00001,ko03029	-	-	-	Methyltransf_28
WH3_k127_5066527_3	1479239.JQMU01000001_gene1144	5.33e-59	207.0	COG4731@1|root,COG4731@2|Bacteria,1N7E7@1224|Proteobacteria,2UHSI@28211|Alphaproteobacteria,2K60R@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
WH3_k127_507100_5	1248917.ANFX01000032_gene932	1.152e-100	345.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,2K07H@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WH3_k127_507100_1	1479239.JQMU01000001_gene750	6.793e-213	678.0	COG3249@1|root,COG3249@2|Bacteria,1R81G@1224|Proteobacteria,2U1EP@28211|Alphaproteobacteria,2K0TT@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_507100_6	1479239.JQMU01000001_gene749	3.344e-100	331.0	COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,2K4AT@204457|Sphingomonadales	204457|Sphingomonadales	L	ATPase involved in DNA replication	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA
WH3_k127_507100_3	1122970.AUHC01000008_gene58	5.595e-142	452.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,2K2GH@204457|Sphingomonadales	204457|Sphingomonadales	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
WH3_k127_507100_8	1479239.JQMU01000001_gene747	4.987e-66	226.0	2CCMQ@1|root,32RW3@2|Bacteria,1MZHB@1224|Proteobacteria,2UCC9@28211|Alphaproteobacteria,2K53Z@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2794
WH3_k127_507100_7	1248917.ANFX01000032_gene927	1.883e-84	286.0	2AZX3@1|root,31S6U@2|Bacteria,1RJH6@1224|Proteobacteria,2UDV0@28211|Alphaproteobacteria,2K6BJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
WH3_k127_507100_2	1479239.JQMU01000001_gene746	4.372e-188	589.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,2K07N@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH3_k127_507100_4	1248917.ANFX01000032_gene925	4.231e-122	394.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,2K1ZP@204457|Sphingomonadales	204457|Sphingomonadales	S	Phosphoglycolate phosphatase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WH3_k127_507100_0	1479239.JQMU01000001_gene744	4.631e-224	716.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,2K246@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
WH3_k127_507100_9	1248917.ANFX01000032_gene922	2.829e-15	80.0	COG1403@1|root,COG1403@2|Bacteria,1MZVF@1224|Proteobacteria,2UBUF@28211|Alphaproteobacteria,2K5ZU@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5075717_1	1479239.JQMU01000001_gene466	5.547e-172	542.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,2K1MA@204457|Sphingomonadales	204457|Sphingomonadales	O	cytochrome C	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WH3_k127_5075717_3	1479239.JQMU01000001_gene467	3.85e-80	271.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,2K56Y@204457|Sphingomonadales	204457|Sphingomonadales	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
WH3_k127_5075717_2	1479239.JQMU01000001_gene469	2.916e-144	460.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,2K13J@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
WH3_k127_5075717_0	1479239.JQMU01000001_gene470	8.062e-198	619.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2K0AY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WH3_k127_5111489_5	1479239.JQMU01000001_gene2319	3.955e-134	432.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,2K1SG@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the precorrin methyltransferase family	cysG	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
WH3_k127_5111489_7	1479239.JQMU01000001_gene2318	1.032e-55	197.0	2EG12@1|root,339T3@2|Bacteria,1NGID@1224|Proteobacteria,2UK0A@28211|Alphaproteobacteria,2K5XT@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2849)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2849
WH3_k127_5111489_0	1479239.JQMU01000001_gene2317	0.0	1049.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,2K14A@204457|Sphingomonadales	204457|Sphingomonadales	C	Sulfite reductase	cysI	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
WH3_k127_5111489_8	1123269.NX02_13425	1.905e-46	171.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2UA02@28211|Alphaproteobacteria,2K4PM@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
WH3_k127_5111489_4	1248917.ANFX01000036_gene1910	4.929e-150	479.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2U5AP@28211|Alphaproteobacteria,2K0FD@204457|Sphingomonadales	204457|Sphingomonadales	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
WH3_k127_5111489_3	1479239.JQMU01000001_gene2314	6.301e-163	518.0	COG0702@1|root,COG0702@2|Bacteria,1RCCP@1224|Proteobacteria,2TU1D@28211|Alphaproteobacteria,2K0TF@204457|Sphingomonadales	204457|Sphingomonadales	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WH3_k127_5111489_2	1248917.ANFX01000036_gene1912	9.623e-191	602.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,2K0DF@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WH3_k127_5111489_1	1248917.ANFX01000036_gene1913	8.59e-213	662.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,2K1GJ@204457|Sphingomonadales	204457|Sphingomonadales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
WH3_k127_5111489_6	1248917.ANFX01000012_gene1901	9.986e-81	270.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,2K12C@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
WH3_k127_511712_0	1479239.JQMU01000001_gene2428	4.431e-128	412.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K1MV@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_511712_1	1479239.JQMU01000001_gene2427	2.058e-75	256.0	2DNUQ@1|root,32Z94@2|Bacteria,1N0X4@1224|Proteobacteria,2UD63@28211|Alphaproteobacteria,2K6AA@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
WH3_k127_511712_2	1479239.JQMU01000001_gene2426	4.795e-46	167.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,2UBX1@28211|Alphaproteobacteria,2K6FP@204457|Sphingomonadales	204457|Sphingomonadales	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WH3_k127_517135_3	1248917.ANFX01000012_gene1760	3.668e-30	119.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2TRMS@28211|Alphaproteobacteria,2K12A@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WH3_k127_517135_2	1248917.ANFX01000012_gene1761	1.398e-171	544.0	COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,2U0C4@28211|Alphaproteobacteria,2K2TQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WH3_k127_517135_1	1248917.ANFX01000012_gene1762	3.998e-232	720.0	COG2141@1|root,COG2141@2|Bacteria,1MWMV@1224|Proteobacteria,2TTIQ@28211|Alphaproteobacteria,2K0FP@204457|Sphingomonadales	204457|Sphingomonadales	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
WH3_k127_517135_0	279238.Saro_2441	7.776e-236	735.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,2K01R@204457|Sphingomonadales	204457|Sphingomonadales	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WH3_k127_5175225_5	1479239.JQMU01000001_gene483	1.079e-124	403.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,2JZY1@204457|Sphingomonadales	204457|Sphingomonadales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WH3_k127_5175225_2	1479239.JQMU01000001_gene484	9.307e-156	497.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,2K0DP@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WH3_k127_5175225_1	1479239.JQMU01000001_gene485	3.282e-156	496.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,2K1B9@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
WH3_k127_5175225_4	1479239.JQMU01000001_gene486	1.161e-145	465.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,2K019@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
WH3_k127_5175225_0	1479239.JQMU01000001_gene487	3.747e-223	694.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TU94@28211|Alphaproteobacteria,2K2VX@204457|Sphingomonadales	204457|Sphingomonadales	I	COG0332 3-oxoacyl- acyl-carrier-protein synthase III	-	-	2.3.1.207	ko:K16872	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C
WH3_k127_5175225_3	1122970.AUHC01000009_gene288	8.634e-151	484.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2TTDJ@28211|Alphaproteobacteria,2K1MT@204457|Sphingomonadales	204457|Sphingomonadales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WH3_k127_5175225_6	1479239.JQMU01000001_gene489	4.049e-37	143.0	COG1009@1|root,COG1009@2|Bacteria,1MW9F@1224|Proteobacteria,2TUR7@28211|Alphaproteobacteria,2K1SD@204457|Sphingomonadales	204457|Sphingomonadales	CP	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit	-	-	1.6.5.3	ko:K05577	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WH3_k127_5188050_0	1479239.JQMU01000001_gene2499	4.75e-132	423.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2UG4M@28211|Alphaproteobacteria,2K43A@204457|Sphingomonadales	204457|Sphingomonadales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WH3_k127_5188050_2	1248917.ANFX01000037_gene2062	1.359e-62	218.0	2AGW3@1|root,3174G@2|Bacteria,1NJ32@1224|Proteobacteria,2UN3I@28211|Alphaproteobacteria,2K7BC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5188050_1	383381.EH30_02950	1.359e-84	281.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2U73K@28211|Alphaproteobacteria,2K4HA@204457|Sphingomonadales	204457|Sphingomonadales	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
WH3_k127_5188050_3	383381.EH30_02945	3.958e-22	96.0	COG1977@1|root,COG1977@2|Bacteria,1NKJE@1224|Proteobacteria,2UKXA@28211|Alphaproteobacteria,2K7QU@204457|Sphingomonadales	204457|Sphingomonadales	H	Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WH3_k127_5201227_0	1479239.JQMU01000001_gene2658	0.0	1193.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,2JZYI@204457|Sphingomonadales	204457|Sphingomonadales	M	Penicillin-binding Protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WH3_k127_5201227_1	1479239.JQMU01000001_gene2659	9.215e-26	107.0	2923J@1|root,2ZPNK@2|Bacteria,1NHX1@1224|Proteobacteria,2UC0M@28211|Alphaproteobacteria,2K5BN@204457|Sphingomonadales	204457|Sphingomonadales	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
WH3_k127_5209166_1	1479239.JQMU01000001_gene1861	1.804e-114	373.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria,2K0MU@204457|Sphingomonadales	204457|Sphingomonadales	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
WH3_k127_5209166_0	1479239.JQMU01000001_gene1862	4.264e-160	511.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,2K10R@204457|Sphingomonadales	204457|Sphingomonadales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
WH3_k127_5209166_2	1479239.JQMU01000001_gene1863	7.739e-58	204.0	2B20I@1|root,31UH7@2|Bacteria,1NA6V@1224|Proteobacteria,2UIZX@28211|Alphaproteobacteria,2K771@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5209166_3	1479239.JQMU01000001_gene1864	1.986e-19	87.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,2K287@204457|Sphingomonadales	204457|Sphingomonadales	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WH3_k127_5220933_1	1479239.JQMU01000001_gene2229	1.028e-80	276.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,2K00X@204457|Sphingomonadales	204457|Sphingomonadales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WH3_k127_5220933_0	1479239.JQMU01000001_gene2228	0.0	1083.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2K1S8@204457|Sphingomonadales	204457|Sphingomonadales	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
WH3_k127_522780_3	1479239.JQMU01000001_gene691	6.214e-120	387.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2U1PN@28211|Alphaproteobacteria,2KCZM@204457|Sphingomonadales	204457|Sphingomonadales	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
WH3_k127_522780_0	1234595.C725_2352	9.842e-302	961.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TS4W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_522780_4	1479239.JQMU01000001_gene2533	2.545e-74	263.0	2C2HV@1|root,33YYU@2|Bacteria,1RJ8M@1224|Proteobacteria,2U9F2@28211|Alphaproteobacteria,2K4XT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_522780_1	1479239.JQMU01000001_gene2532	9.071e-206	643.0	COG3000@1|root,COG3000@2|Bacteria,1QNUX@1224|Proteobacteria,2U0G7@28211|Alphaproteobacteria,2K1MP@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH3_k127_522780_2	1479239.JQMU01000001_gene2531	1.701e-152	486.0	COG2197@1|root,COG2197@2|Bacteria,1MVNV@1224|Proteobacteria,2TTK7@28211|Alphaproteobacteria,2K2EX@204457|Sphingomonadales	204457|Sphingomonadales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WH3_k127_5244187_0	1479239.JQMU01000001_gene2843	1.208e-293	904.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JZZC@204457|Sphingomonadales	204457|Sphingomonadales	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
WH3_k127_5244187_1	1479239.JQMU01000001_gene2842	1.362e-215	672.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,2K2A7@204457|Sphingomonadales	204457|Sphingomonadales	S	AFG1 family ATPase	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
WH3_k127_5244187_5	1479239.JQMU01000001_gene2841	7.115e-86	285.0	COG2050@1|root,COG2050@2|Bacteria,1MZPH@1224|Proteobacteria,2UDIQ@28211|Alphaproteobacteria,2K62E@204457|Sphingomonadales	204457|Sphingomonadales	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH3_k127_5244187_2	1479239.JQMU01000001_gene2840	1.769e-171	546.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,2K0CN@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17
WH3_k127_5244187_4	1479239.JQMU01000001_gene2839	1.588e-121	394.0	COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,2U7DM@28211|Alphaproteobacteria,2K1FQ@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WH3_k127_5244187_3	1479239.JQMU01000001_gene2838	1.766e-167	531.0	COG1181@1|root,COG1181@2|Bacteria,1R3ZP@1224|Proteobacteria,2U2UN@28211|Alphaproteobacteria,2K0XV@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WH3_k127_5244187_6	1479239.JQMU01000001_gene2837	5.412e-29	122.0	COG4076@1|root,COG4076@2|Bacteria,1QU4H@1224|Proteobacteria,2TVZ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5287885_0	1479239.JQMU01000001_gene1663	0.0	1362.0	COG1222@1|root,COG1222@2|Bacteria,1QTV4@1224|Proteobacteria,2U0Q7@28211|Alphaproteobacteria,2K0N9@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
WH3_k127_5291372_3	1479239.JQMU01000001_gene2012	1.606e-21	93.0	COG3861@1|root,COG3861@2|Bacteria,1NU42@1224|Proteobacteria,2TTV5@28211|Alphaproteobacteria,2K0VQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Photosynthetic reaction centre, H-chain N-terminal region	-	-	-	ko:K13991	ko02020,map02020	-	-	-	ko00000,ko00001,ko00194	-	-	-	PRC,PRCH
WH3_k127_5291372_0	1479239.JQMU01000001_gene2013	2.358e-271	842.0	COG0477@1|root,COG2814@2|Bacteria,1MW95@1224|Proteobacteria,2TS8H@28211|Alphaproteobacteria,2K2JK@204457|Sphingomonadales	204457|Sphingomonadales	EGP	PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
WH3_k127_5291372_2	1248917.ANFX01000016_gene2473	3.546e-132	425.0	COG2227@1|root,COG2227@2|Bacteria,1N2VZ@1224|Proteobacteria,2TU4Z@28211|Alphaproteobacteria,2K2H0@204457|Sphingomonadales	204457|Sphingomonadales	H	Magnesium-protoporphyrin IX methyltransferase C-terminus	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	MTS,Mg-por_mtran_C,PrmA
WH3_k127_5291372_1	1248917.ANFX01000016_gene2472	4.415e-142	451.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria,2K1YK@204457|Sphingomonadales	204457|Sphingomonadales	D	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP	nifH	-	1.18.6.1,1.3.7.7	ko:K02588,ko:K04037	ko00625,ko00860,ko00910,ko01100,ko01110,ko01120,map00625,map00860,map00910,map01100,map01110,map01120	M00175	R05185,R05496,R06282	RC00002,RC01008,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
WH3_k127_532740_1	1479239.JQMU01000001_gene1989	1.644e-105	344.0	COG0545@1|root,COG0545@2|Bacteria,1RKD4@1224|Proteobacteria,2UANS@28211|Alphaproteobacteria,2KDTM@204457|Sphingomonadales	204457|Sphingomonadales	O	Peptidyl-prolyl cis-trans	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
WH3_k127_532740_4	314225.ELI_01355	2.051e-29	117.0	COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UC58@28211|Alphaproteobacteria,2K5X3@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WH3_k127_532740_3	1248917.ANFX01000016_gene2514	2.773e-49	179.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,2K5ZR@204457|Sphingomonadales	204457|Sphingomonadales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
WH3_k127_532740_0	1479239.JQMU01000001_gene1986	9.869e-211	665.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,2K1YR@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
WH3_k127_532740_2	1122970.AUHC01000004_gene2221	1.436e-56	198.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2U5JV@28211|Alphaproteobacteria,2K2BS@204457|Sphingomonadales	204457|Sphingomonadales	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
WH3_k127_533948_11	1248917.ANFX01000035_gene1973	6.01e-93	305.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2TR7D@28211|Alphaproteobacteria,2K1KA@204457|Sphingomonadales	204457|Sphingomonadales	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
WH3_k127_533948_12	1122970.AUHC01000013_gene1017	1.542e-84	282.0	COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2TQQ2@28211|Alphaproteobacteria,2K42I@204457|Sphingomonadales	204457|Sphingomonadales	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
WH3_k127_533948_2	1248917.ANFX01000035_gene1978	3.443e-221	696.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TUFK@28211|Alphaproteobacteria,2KDCF@204457|Sphingomonadales	204457|Sphingomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_533948_5	1122970.AUHC01000013_gene1020	9.629e-160	509.0	COG0845@1|root,COG0845@2|Bacteria,1NBFC@1224|Proteobacteria,2U0PI@28211|Alphaproteobacteria,2K9CX@204457|Sphingomonadales	204457|Sphingomonadales	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
WH3_k127_533948_8	1248917.ANFX01000035_gene1980	9.208e-142	459.0	COG1136@1|root,COG1136@2|Bacteria,1QT8W@1224|Proteobacteria,2U3UE@28211|Alphaproteobacteria,2K59B@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WH3_k127_533948_3	1479239.JQMU01000001_gene1762	3.062e-210	657.0	COG0577@1|root,COG0577@2|Bacteria,1P0WE@1224|Proteobacteria,2VG3S@28211|Alphaproteobacteria,2K8ND@204457|Sphingomonadales	204457|Sphingomonadales	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WH3_k127_533948_10	1248917.ANFX01000035_gene1982	5.702e-99	327.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,2U0MU@28211|Alphaproteobacteria,2K65U@204457|Sphingomonadales	204457|Sphingomonadales	K	AefR-like transcriptional repressor, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_7,TetR_N
WH3_k127_533948_0	1479239.JQMU01000001_gene1764	0.0	1208.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,2K1U5@204457|Sphingomonadales	204457|Sphingomonadales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WH3_k127_533948_13	1219049.SP5_045_00060	7.803e-84	284.0	COG3751@1|root,COG3751@2|Bacteria,1RE5K@1224|Proteobacteria,2UDIR@28211|Alphaproteobacteria,2KE40@204457|Sphingomonadales	204457|Sphingomonadales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_4
WH3_k127_533948_7	1248917.ANFX01000035_gene1986	4.645e-144	465.0	COG1566@1|root,COG1566@2|Bacteria,1N1WR@1224|Proteobacteria,2VGP8@28211|Alphaproteobacteria,2KE54@204457|Sphingomonadales	204457|Sphingomonadales	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
WH3_k127_533948_9	1479239.JQMU01000001_gene1767	1.209e-136	437.0	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,2TUDH@28211|Alphaproteobacteria,2JZW4@204457|Sphingomonadales	204457|Sphingomonadales	D	Chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
WH3_k127_533948_14	1479239.JQMU01000001_gene1768	8.181e-60	208.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria,2K5I6@204457|Sphingomonadales	204457|Sphingomonadales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
WH3_k127_533948_4	1122970.AUHC01000013_gene1030	6.152e-191	602.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2U2TG@28211|Alphaproteobacteria,2K02V@204457|Sphingomonadales	204457|Sphingomonadales	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
WH3_k127_533948_6	1248917.ANFX01000040_gene773	1.27e-150	480.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,2K3T2@204457|Sphingomonadales	204457|Sphingomonadales	C	Citrate synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Citrate_synt
WH3_k127_533948_1	1479239.JQMU01000001_gene388	3.451e-229	712.0	COG1804@1|root,COG1804@2|Bacteria,1P68A@1224|Proteobacteria,2TR4B@28211|Alphaproteobacteria,2K371@204457|Sphingomonadales	204457|Sphingomonadales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WH3_k127_533948_15	1545915.JROG01000004_gene2621	2.605e-59	213.0	COG1414@1|root,COG1414@2|Bacteria,1QYTM@1224|Proteobacteria,2U04P@28211|Alphaproteobacteria,2K2VC@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
WH3_k127_5383862_1	59538.XP_005981131.1	7.927e-81	272.0	COG0129@1|root,KOG2448@2759|Eukaryota,39TNU@33154|Opisthokonta,3CNNX@33208|Metazoa,3E4UJ@33213|Bilateria	33154|Opisthokonta	E	Dehydratase family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
WH3_k127_5383862_0	1123240.ATVO01000005_gene1688	6.119e-109	357.0	COG1028@1|root,COG1028@2|Bacteria,1MXTP@1224|Proteobacteria,2TQST@28211|Alphaproteobacteria,2K1SJ@204457|Sphingomonadales	204457|Sphingomonadales	IQ	reductase	-	-	1.1.1.175	ko:K22185	ko00040,map00040	-	R01429	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WH3_k127_5383862_2	1123240.ATVO01000005_gene1689	4.866e-44	162.0	COG0800@1|root,COG0800@2|Bacteria,1RD0T@1224|Proteobacteria,2U7AQ@28211|Alphaproteobacteria,2K1WJ@204457|Sphingomonadales	204457|Sphingomonadales	G	Aldolase	-	-	4.1.2.21	ko:K01631	ko00052,ko01100,map00052,map01100	M00552	R01064	RC00307,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
WH3_k127_540130_2	314225.ELI_09615	4.668e-173	551.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2TVI8@28211|Alphaproteobacteria,2K092@204457|Sphingomonadales	204457|Sphingomonadales	G	COG2211 Na melibiose symporter and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
WH3_k127_540130_0	1248917.ANFX01000020_gene2251	1.108e-286	882.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,2JZVP@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_540130_1	1479239.JQMU01000001_gene835	1.194e-216	675.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria,2K0RB@204457|Sphingomonadales	204457|Sphingomonadales	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WH3_k127_540130_3	1479239.JQMU01000001_gene836	3.016e-130	419.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,2K142@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
WH3_k127_5432872_5	1479239.JQMU01000001_gene1889	3.368e-56	197.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TS9V@28211|Alphaproteobacteria,2K1VI@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GGDEF
WH3_k127_5432872_2	1479239.JQMU01000001_gene1888	6.213e-269	839.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K1AE@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,Protoglobin
WH3_k127_5432872_0	1479239.JQMU01000001_gene1887	8.556e-285	887.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K1AE@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,Protoglobin
WH3_k127_5432872_3	1248917.ANFX01000049_gene1626	5.711e-245	766.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2U42R@28211|Alphaproteobacteria,2K2MK@204457|Sphingomonadales	204457|Sphingomonadales	S	Tat pathway signal protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
WH3_k127_5432872_1	1248917.ANFX01000049_gene1627	2.282e-274	856.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2U0PM@28211|Alphaproteobacteria,2K113@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
WH3_k127_5432872_4	1479239.JQMU01000001_gene1886	1.978e-129	420.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,2U0K0@28211|Alphaproteobacteria,2K2YW@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
WH3_k127_5432872_6	1217713.F993_01835	4.892e-16	80.0	COG3076@1|root,COG3076@2|Bacteria,1N195@1224|Proteobacteria,1SD9D@1236|Gammaproteobacteria,3NMNZ@468|Moraxellaceae	1236|Gammaproteobacteria	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695,RraB
WH3_k127_5452077_6	1479239.JQMU01000001_gene159	5.297e-28	115.0	COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,2TUQA@28211|Alphaproteobacteria,2K2PT@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C13
WH3_k127_5452077_0	1248917.ANFX01000030_gene537	0.0	1239.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,2K1NE@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WH3_k127_5452077_3	1248917.ANFX01000030_gene536	1.09e-63	220.0	COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,2UC3G@28211|Alphaproteobacteria,2K550@204457|Sphingomonadales	204457|Sphingomonadales	C	succinate dehydrogenase	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WH3_k127_5452077_2	314225.ELI_07165	1.639e-64	222.0	COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,2K6ED@204457|Sphingomonadales	204457|Sphingomonadales	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WH3_k127_5452077_1	1479239.JQMU01000001_gene164	5.412e-129	415.0	COG1028@1|root,COG1028@2|Bacteria,1R8HN@1224|Proteobacteria,2U61U@28211|Alphaproteobacteria,2KCF7@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_5452077_4	383381.EH30_07030	7.627e-43	158.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,2K7E5@204457|Sphingomonadales	204457|Sphingomonadales	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
WH3_k127_5452077_5	383381.EH30_07045	2.936e-30	121.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,2K0Q7@204457|Sphingomonadales	204457|Sphingomonadales	J	ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WH3_k127_545484_2	1479239.JQMU01000001_gene1161	1.612e-77	261.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TQXN@28211|Alphaproteobacteria,2K0TU@204457|Sphingomonadales	204457|Sphingomonadales	E	aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
WH3_k127_545484_0	1479239.JQMU01000001_gene1160	0.0	1264.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria,2K19E@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WH3_k127_545484_3	1479239.JQMU01000001_gene1159	5.826e-74	253.0	COG0824@1|root,COG0824@2|Bacteria,1N06V@1224|Proteobacteria,2UCAQ@28211|Alphaproteobacteria,2K5A4@204457|Sphingomonadales	204457|Sphingomonadales	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
WH3_k127_545484_1	1479239.JQMU01000001_gene1158	1.385e-281	872.0	COG2199@1|root,COG3706@2|Bacteria,1MW39@1224|Proteobacteria,2U25F@28211|Alphaproteobacteria,2KDVH@204457|Sphingomonadales	204457|Sphingomonadales	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
WH3_k127_5459451_2	1248760.ANFZ01000014_gene2068	1.114e-19	101.0	COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,2U363@28211|Alphaproteobacteria,2K0JZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Copper resistance	-	-	-	ko:K07233	-	-	-	-	ko00000	-	-	-	CopB
WH3_k127_5459451_0	1122970.AUHC01000001_gene677	2.04e-316	975.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,2K0US@204457|Sphingomonadales	204457|Sphingomonadales	Q	Copper-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WH3_k127_5459451_1	1479239.JQMU01000001_gene1077	1.662e-196	617.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2K2YY@204457|Sphingomonadales	28211|Alphaproteobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5472415_5	1248917.ANFX01000013_gene1498	1.264e-100	330.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,2K20T@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
WH3_k127_5472415_3	1248917.ANFX01000013_gene1497	5.96e-138	446.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,2K0E3@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WH3_k127_5472415_6	1479239.JQMU01000001_gene1474	9.824e-86	287.0	COG2852@1|root,COG2852@2|Bacteria,1QUPM@1224|Proteobacteria,2TW3G@28211|Alphaproteobacteria,2K4ZB@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WH3_k127_5472415_0	1248917.ANFX01000013_gene1495	6.259e-315	967.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,2K196@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WH3_k127_5472415_7	1479239.JQMU01000001_gene1471	1.591e-76	258.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2U9Z9@28211|Alphaproteobacteria,2KD5Z@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WH3_k127_5472415_4	1122970.AUHC01000011_gene2731	2.934e-110	365.0	COG2207@1|root,COG2207@2|Bacteria,1RKX7@1224|Proteobacteria,2UB2T@28211|Alphaproteobacteria,2K4KU@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WH3_k127_5472415_1	1479239.JQMU01000001_gene1469	1.296e-307	951.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0GU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WH3_k127_5472415_2	1479239.JQMU01000001_gene1467	8.593e-141	452.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria,2K1QF@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WH3_k127_5475485_1	1479239.JQMU01000001_gene2143	1.706e-81	272.0	COG5373@1|root,COG5373@2|Bacteria,1N5K2@1224|Proteobacteria,2UB74@28211|Alphaproteobacteria,2JZY7@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	tolA	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5475485_0	1479239.JQMU01000001_gene2144	1e-295	912.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2K1NT@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WH3_k127_5475485_2	1248917.ANFX01000020_gene2230	3.872e-05	46.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U7XJ@28211|Alphaproteobacteria,2KD75@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
WH3_k127_5483928_2	161528.ED21_21459	1.429e-12	68.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,2K15Q@204457|Sphingomonadales	204457|Sphingomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WH3_k127_5483928_0	1248917.ANFX01000020_gene2221	1.036e-168	536.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,2K084@204457|Sphingomonadales	204457|Sphingomonadales	H	coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
WH3_k127_5483928_1	1479239.JQMU01000001_gene2152	5.727e-136	434.0	COG1407@1|root,COG1407@2|Bacteria,1RC5G@1224|Proteobacteria,2TU2T@28211|Alphaproteobacteria,2K25E@204457|Sphingomonadales	204457|Sphingomonadales	S	ICC-like phosphoesterases	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
WH3_k127_550010_0	1479239.JQMU01000001_gene2272	2.61e-129	413.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,2K06N@204457|Sphingomonadales	204457|Sphingomonadales	E	highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WH3_k127_550010_1	1479239.JQMU01000001_gene2271	1.749e-128	414.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2UQK5@28211|Alphaproteobacteria,2K8RB@204457|Sphingomonadales	204457|Sphingomonadales	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
WH3_k127_5503497_9	1248917.ANFX01000016_gene2498	3.664e-11	64.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TU0K@28211|Alphaproteobacteria,2K083@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
WH3_k127_5503497_4	1479239.JQMU01000001_gene1999	2.035e-160	513.0	COG1252@1|root,COG1252@2|Bacteria,1QUKT@1224|Proteobacteria,2TW32@28211|Alphaproteobacteria,2K904@204457|Sphingomonadales	204457|Sphingomonadales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WH3_k127_5503497_0	1479239.JQMU01000001_gene1998	3.895e-313	966.0	COG2274@1|root,COG2274@2|Bacteria,1MXTI@1224|Proteobacteria,2TUN0@28211|Alphaproteobacteria,2K1TC@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02021	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH3_k127_5503497_3	1479239.JQMU01000001_gene1997	3.221e-184	581.0	COG0845@1|root,COG0845@2|Bacteria,1PZ6R@1224|Proteobacteria,2TTYA@28211|Alphaproteobacteria,2K1H3@204457|Sphingomonadales	204457|Sphingomonadales	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
WH3_k127_5503497_2	1122970.AUHC01000004_gene2233	3.424e-237	742.0	COG1538@1|root,COG1538@2|Bacteria,1MXB2@1224|Proteobacteria,2U4BD@28211|Alphaproteobacteria,2K01H@204457|Sphingomonadales	204457|Sphingomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WH3_k127_5503497_5	1122970.AUHC01000004_gene2232	3.551e-137	445.0	2AKGN@1|root,31B8I@2|Bacteria,1Q70U@1224|Proteobacteria,2VD4K@28211|Alphaproteobacteria,2K467@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5503497_6	1122970.AUHC01000004_gene2231	3.746e-91	305.0	29ES0@1|root,301PT@2|Bacteria,1Q96T@1224|Proteobacteria,2VDCE@28211|Alphaproteobacteria,2K4Z3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5503497_7	383381.EH30_01470	2.987e-86	286.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2U78W@28211|Alphaproteobacteria,2K4QN@204457|Sphingomonadales	204457|Sphingomonadales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WH3_k127_5503497_8	1545915.JROG01000009_gene2672	1.784e-54	200.0	COG1073@1|root,COG1073@2|Bacteria,1RBYZ@1224|Proteobacteria,2UBZ4@28211|Alphaproteobacteria,2KASF@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
WH3_k127_5503497_1	1479239.JQMU01000001_gene1994	1.604e-273	843.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,2K04H@204457|Sphingomonadales	204457|Sphingomonadales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WH3_k127_5510423_1	1248917.ANFX01000040_gene797	5.067e-209	651.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2JZXP@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WH3_k127_5510423_3	1248917.ANFX01000040_gene796	1.275e-69	239.0	COG3788@1|root,COG3788@2|Bacteria,1NBHH@1224|Proteobacteria,2UA0K@28211|Alphaproteobacteria,2K7W6@204457|Sphingomonadales	204457|Sphingomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
WH3_k127_5510423_0	237727.NAP1_11213	1.24e-256	799.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2TSXW@28211|Alphaproteobacteria,2K1KD@204457|Sphingomonadales	204457|Sphingomonadales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_5510423_2	1248917.ANFX01000013_gene1533	3.662e-149	479.0	COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,2U363@28211|Alphaproteobacteria,2K0JZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Copper resistance	-	-	-	ko:K07233	-	-	-	-	ko00000	-	-	-	CopB
WH3_k127_5510423_4	1545915.JROG01000001_gene297	1.926e-14	72.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,2K0US@204457|Sphingomonadales	204457|Sphingomonadales	Q	Copper-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WH3_k127_5514124_0	1479239.JQMU01000001_gene2211	3.541e-228	709.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2TRKT@28211|Alphaproteobacteria,2K1GX@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WH3_k127_5514124_1	1248917.ANFX01000012_gene1801	8.643e-113	365.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,2K25I@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WH3_k127_5517361_2	1479239.JQMU01000001_gene734	2.949e-81	271.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2K1J2@204457|Sphingomonadales	204457|Sphingomonadales	Q	dioxygenase	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
WH3_k127_5517361_0	1479239.JQMU01000001_gene733	1.432e-245	771.0	COG0265@1|root,COG0265@2|Bacteria,1R5U1@1224|Proteobacteria,2U3GT@28211|Alphaproteobacteria,2KDBK@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
WH3_k127_5517361_3	1248917.ANFX01000032_gene909	3.985e-33	136.0	2AAJM@1|root,30ZX0@2|Bacteria,1P680@1224|Proteobacteria,2UYDV@28211|Alphaproteobacteria,2K8CA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5517361_1	1248917.ANFX01000032_gene907	1.446e-109	358.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2K165@204457|Sphingomonadales	204457|Sphingomonadales	FL	Metal binding domain of Ada	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
WH3_k127_5540334_6	237727.NAP1_14078	1.33e-93	309.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2K093@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_5540334_12	1479239.JQMU01000001_gene1174	7.229e-19	91.0	2AME8@1|root,31C9P@2|Bacteria,1PA5E@1224|Proteobacteria,2UY8Q@28211|Alphaproteobacteria,2K7U8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5540334_3	1248917.ANFX01000013_gene1456	4.602e-152	490.0	COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria,2U3Y9@28211|Alphaproteobacteria,2K0EA@204457|Sphingomonadales	204457|Sphingomonadales	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
WH3_k127_5540334_7	383381.EH30_13890	1.322e-75	258.0	COG3153@1|root,COG3153@2|Bacteria,1RA42@1224|Proteobacteria,2UA4N@28211|Alphaproteobacteria,2K5NF@204457|Sphingomonadales	204457|Sphingomonadales	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
WH3_k127_5540334_1	1479239.JQMU01000001_gene1172	1.116e-192	619.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,2TR82@28211|Alphaproteobacteria,2K0DD@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
WH3_k127_5540334_2	1479239.JQMU01000001_gene1171	2.401e-162	512.0	COG0708@1|root,COG0708@2|Bacteria,1MVMC@1224|Proteobacteria,2TRWQ@28211|Alphaproteobacteria,2K09T@204457|Sphingomonadales	204457|Sphingomonadales	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WH3_k127_5540334_0	1248917.ANFX01000013_gene1453	6.46e-245	782.0	COG1785@1|root,COG1785@2|Bacteria,1MXI2@1224|Proteobacteria,2TTUZ@28211|Alphaproteobacteria,2K1RI@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
WH3_k127_5540334_5	1479239.JQMU01000001_gene1169	3.334e-113	371.0	COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria,2K43J@204457|Sphingomonadales	204457|Sphingomonadales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	-	-	-	-	-	-	-	-	-	LolA
WH3_k127_5540334_10	1479239.JQMU01000001_gene1168	6.897e-28	112.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria,2K6VC@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
WH3_k127_5540334_8	1479239.JQMU01000001_gene1167	4.586e-68	233.0	COG0216@1|root,COG0216@2|Bacteria,1R348@1224|Proteobacteria,2TZXT@28211|Alphaproteobacteria,2KEW4@204457|Sphingomonadales	204457|Sphingomonadales	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
WH3_k127_5540334_4	1479239.JQMU01000001_gene1166	3.389e-121	392.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2TSCG@28211|Alphaproteobacteria,2K0XZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Pseudouridine synthase	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
WH3_k127_5540334_9	1479239.JQMU01000001_gene1165	1.388e-67	231.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TUBY@28211|Alphaproteobacteria,2K1FB@204457|Sphingomonadales	204457|Sphingomonadales	EH	component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
WH3_k127_555228_2	1183438.GKIL_2919	2.344e-108	370.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria	2|Bacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WH3_k127_555228_1	1479239.JQMU01000001_gene2554	2.078e-194	608.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,2K0PF@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
WH3_k127_555228_0	1479239.JQMU01000001_gene2555	1.322e-265	821.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TSEI@28211|Alphaproteobacteria,2K13V@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
WH3_k127_555228_3	1479239.JQMU01000001_gene2556	1.222e-26	110.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,2K02S@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WH3_k127_5569198_3	1122970.AUHC01000009_gene201	7.185e-20	92.0	2FDQI@1|root,345RK@2|Bacteria,1NE6V@1224|Proteobacteria,2UJM5@28211|Alphaproteobacteria,2K7PF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5569198_2	383381.EH30_08115	1.02e-70	244.0	COG1309@1|root,COG1309@2|Bacteria,1NEAF@1224|Proteobacteria,2UIAX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WH3_k127_5569198_0	1248917.ANFX01000023_gene1219	3.774e-248	769.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,2K056@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WH3_k127_5569198_1	1044.EH31_03955	5.728e-95	323.0	COG2519@1|root,COG2519@2|Bacteria,1QUNX@1224|Proteobacteria,2TW2F@28211|Alphaproteobacteria,2KBD7@204457|Sphingomonadales	204457|Sphingomonadales	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
WH3_k127_5599206_3	366602.Caul_2095	8.115e-32	138.0	COG3166@1|root,COG3166@2|Bacteria	2|Bacteria	NU	PFAM Fimbrial assembly family protein	xpsL	-	-	ko:K02461,ko:K02662,ko:K02663	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	PilN,T2SSL
WH3_k127_5599206_4	366602.Caul_2094	2.263e-30	132.0	COG4795@1|root,COG4795@2|Bacteria,1MYPS@1224|Proteobacteria,2UND2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	General Secretion Pathway protein	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
WH3_k127_5599206_6	1131814.JAFO01000001_gene1830	0.0003502	49.0	COG4967@1|root,COG4967@2|Bacteria,1N7XY@1224|Proteobacteria,2UGHB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
WH3_k127_5599206_2	745411.B3C1_05937	4.159e-46	172.0	COG4968@1|root,COG4968@2|Bacteria,1QW3U@1224|Proteobacteria,1T3FM@1236|Gammaproteobacteria,1JC2R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
WH3_k127_5599206_1	366602.Caul_2090	4.834e-102	345.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2TV76@28211|Alphaproteobacteria,2KF1B@204458|Caulobacterales	204458|Caulobacterales	U	type II secretion system	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
WH3_k127_5599206_0	366602.Caul_2089	5.408e-191	610.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,2KF4Y@204458|Caulobacterales	204458|Caulobacterales	NU	pathway protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
WH3_k127_5605035_1	1044.EH31_11025	1.112e-112	366.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2TSXZ@28211|Alphaproteobacteria,2K3QP@204457|Sphingomonadales	204457|Sphingomonadales	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_5605035_0	1044.EH31_11020	0.0	1060.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2TQJW@28211|Alphaproteobacteria,2K376@204457|Sphingomonadales	204457|Sphingomonadales	C	Respiratory nitrate reductase alpha N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
WH3_k127_5622065_0	1479239.JQMU01000001_gene1052	0.0	1145.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2K0HX@204457|Sphingomonadales	204457|Sphingomonadales	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WH3_k127_5622065_1	237727.NAP1_15073	2.238e-252	786.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2K08H@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WH3_k127_5622065_4	1122970.AUHC01000002_gene1383	3.356e-153	488.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,2K1HR@204457|Sphingomonadales	204457|Sphingomonadales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
WH3_k127_5622065_2	1248917.ANFX01000050_gene641	3.558e-191	604.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,2K20N@204457|Sphingomonadales	204457|Sphingomonadales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
WH3_k127_5622065_3	1479239.JQMU01000001_gene1048	9.645e-155	494.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2K1RH@204457|Sphingomonadales	204457|Sphingomonadales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
WH3_k127_564167_4	1479239.JQMU01000001_gene926	2.136e-45	166.0	2AJIQ@1|root,31A5H@2|Bacteria,1Q4Z7@1224|Proteobacteria,2V6KG@28211|Alphaproteobacteria,2KAKE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_564167_1	1479239.JQMU01000001_gene925	3.333e-72	248.0	2EP5S@1|root,33GSG@2|Bacteria,1NI0K@1224|Proteobacteria,2UK2B@28211|Alphaproteobacteria,2K7A6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_564167_3	1479239.JQMU01000001_gene924	1.753e-46	171.0	COG2003@1|root,COG2003@2|Bacteria,1P81B@1224|Proteobacteria,2UXT5@28211|Alphaproteobacteria,2KDZA@204457|Sphingomonadales	204457|Sphingomonadales	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WH3_k127_564167_2	1479239.JQMU01000001_gene923	1.936e-53	200.0	COG0745@1|root,COG0745@2|Bacteria	1479239.JQMU01000001_gene923|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_564167_0	1122970.AUHC01000013_gene1031	5.782e-148	474.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria,2K14X@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH3_k127_5687807_3	1248917.ANFX01000019_gene2366	3.511e-112	364.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2K072@204457|Sphingomonadales	204457|Sphingomonadales	E	aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
WH3_k127_5687807_2	1248917.ANFX01000019_gene2367	3.843e-119	388.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,2K13X@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WH3_k127_5687807_4	1479239.JQMU01000001_gene1610	2.386e-104	340.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria,2K1YX@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
WH3_k127_5687807_0	1248917.ANFX01000019_gene2369	8.784e-275	848.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,2K0CE@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
WH3_k127_5687807_1	1122970.AUHC01000016_gene2595	4.544e-164	519.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,2K07X@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
WH3_k127_5687807_5	1479239.JQMU01000001_gene1613	3.591e-103	337.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2TV7J@28211|Alphaproteobacteria,2K25N@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WH3_k127_5687807_6	1479239.JQMU01000001_gene1614	7.732e-07	52.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,2TRIR@28211|Alphaproteobacteria,2K1G5@204457|Sphingomonadales	204457|Sphingomonadales	CP	Domain related to MnhB subunit of Na+/H+ antiporter	phaAB	-	-	ko:K05559	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
WH3_k127_569951_2	1122970.AUHC01000004_gene2268	4.913e-05	47.0	COG2211@1|root,COG2211@2|Bacteria,1MWE4@1224|Proteobacteria,2TQY7@28211|Alphaproteobacteria,2K1IR@204457|Sphingomonadales	204457|Sphingomonadales	G	PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
WH3_k127_569951_0	1479239.JQMU01000001_gene2022	1.487e-169	536.0	COG0382@1|root,COG0382@2|Bacteria,1MVS1@1224|Proteobacteria,2TVKN@28211|Alphaproteobacteria,2K2ED@204457|Sphingomonadales	204457|Sphingomonadales	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
WH3_k127_569951_1	1479239.JQMU01000001_gene2021	3.082e-100	327.0	COG2204@1|root,COG2204@2|Bacteria,1P98K@1224|Proteobacteria,2TUM0@28211|Alphaproteobacteria,2K3AF@204457|Sphingomonadales	204457|Sphingomonadales	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_8
WH3_k127_5700874_1	1479239.JQMU01000001_gene2756	1.416e-157	501.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2K0Y0@204457|Sphingomonadales	204457|Sphingomonadales	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
WH3_k127_5700874_0	1479239.JQMU01000001_gene2755	5.255e-207	646.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,2K0QH@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
WH3_k127_5700874_2	1122970.AUHC01000001_gene524	5.55e-31	124.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,2K1YJ@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
WH3_k127_570964_0	1479239.JQMU01000001_gene2270	2.535e-258	809.0	COG4625@1|root,COG5640@1|root,COG4625@2|Bacteria,COG5640@2|Bacteria,1NS3H@1224|Proteobacteria,2U1SB@28211|Alphaproteobacteria,2K2MI@204457|Sphingomonadales	204457|Sphingomonadales	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR,Peptidase_S8,Trypsin
WH3_k127_581326_1	1479239.JQMU01000001_gene217	6.391e-84	279.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,2K1DQ@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WH3_k127_581326_2	1479239.JQMU01000001_gene218	4.023e-55	194.0	COG4530@1|root,COG4530@2|Bacteria,1N42Z@1224|Proteobacteria,2UDI6@28211|Alphaproteobacteria,2K62H@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
WH3_k127_581326_0	1479239.JQMU01000001_gene219	3.675e-244	763.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,2K0WH@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
WH3_k127_581326_3	1122970.AUHC01000001_gene731	4.496e-37	141.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria,2K3ZM@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WH3_k127_5855810_1	1248917.ANFX01000037_gene2007	2.415e-183	580.0	COG4206@1|root,COG4206@2|Bacteria,1MXFM@1224|Proteobacteria,2TWYV@28211|Alphaproteobacteria,2K14T@204457|Sphingomonadales	204457|Sphingomonadales	H	Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_5855810_0	1479239.JQMU01000001_gene2448	1.093e-230	717.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TTXA@28211|Alphaproteobacteria,2K0J9@204457|Sphingomonadales	204457|Sphingomonadales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WH3_k127_5855810_2	1248917.ANFX01000037_gene2010	3.043e-06	49.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,2K1TK@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
WH3_k127_5871578_0	1479239.JQMU01000001_gene1804	1.217e-161	512.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2TR6J@28211|Alphaproteobacteria,2K025@204457|Sphingomonadales	204457|Sphingomonadales	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
WH3_k127_5871578_2	1479239.JQMU01000001_gene1803	4.55e-49	179.0	COG1677@1|root,COG1677@2|Bacteria,1QDJ8@1224|Proteobacteria,2UG4E@28211|Alphaproteobacteria,2KDKB@204457|Sphingomonadales	204457|Sphingomonadales	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
WH3_k127_5871578_1	1479239.JQMU01000001_gene1802	2.865e-123	398.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2TW3X@28211|Alphaproteobacteria,2K247@204457|Sphingomonadales	204457|Sphingomonadales	KT	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	flrC	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Sigma54_activat
WH3_k127_5953759_1	1479239.JQMU01000001_gene375	1.57e-157	499.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR78@28211|Alphaproteobacteria,2K2PQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.12	ko:K14448	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09293	RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_5953759_5	1479239.JQMU01000001_gene374	6.971e-67	233.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria,2K6Q8@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WH3_k127_5953759_2	1479239.JQMU01000001_gene373	1.294e-146	469.0	COG2365@1|root,COG2365@2|Bacteria,1R4XF@1224|Proteobacteria,2U0KA@28211|Alphaproteobacteria,2K5SR@204457|Sphingomonadales	204457|Sphingomonadales	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
WH3_k127_5953759_0	1479239.JQMU01000001_gene372	4.398e-201	629.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,2K0I2@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH3_k127_5953759_4	1479239.JQMU01000001_gene371	8.786e-71	245.0	COG5331@1|root,COG5331@2|Bacteria,1N0MD@1224|Proteobacteria,2U9ZR@28211|Alphaproteobacteria,2K571@204457|Sphingomonadales	204457|Sphingomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
WH3_k127_5953759_3	1122970.AUHC01000009_gene226	3.608e-79	267.0	COG5331@1|root,COG5331@2|Bacteria,1RI4N@1224|Proteobacteria,2UA3C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
WH3_k127_5953759_6	1248917.ANFX01000041_gene1712	6.733e-57	199.0	COG0500@1|root,COG2226@2|Bacteria,1REUM@1224|Proteobacteria,2U75Q@28211|Alphaproteobacteria,2K51Q@204457|Sphingomonadales	204457|Sphingomonadales	Q	ubiE/COQ5 methyltransferase family	-	-	-	ko:K13623	ko00564,map00564	-	R09073	RC00003,RC02308	ko00000,ko00001	-	-	-	Methyltransf_23,Methyltransf_25
WH3_k127_5977763_11	279238.Saro_0284	0.0002962	43.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,2K02E@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WH3_k127_5977763_0	1479239.JQMU01000001_gene1655	3.368e-271	842.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,2K1Y8@204457|Sphingomonadales	204457|Sphingomonadales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WH3_k127_5977763_9	1122970.AUHC01000002_gene1256	2.113e-57	209.0	COG5373@1|root,COG5373@2|Bacteria,1N7JV@1224|Proteobacteria,2TR7A@28211|Alphaproteobacteria,2K53N@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4167
WH3_k127_5977763_6	1248917.ANFX01000021_gene1674	1.339e-128	416.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,2K12S@204457|Sphingomonadales	204457|Sphingomonadales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
WH3_k127_5977763_3	1479239.JQMU01000001_gene1652	3.942e-217	675.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,2K1M6@204457|Sphingomonadales	204457|Sphingomonadales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WH3_k127_5977763_2	1479239.JQMU01000001_gene1651	1.874e-219	685.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,2K101@204457|Sphingomonadales	204457|Sphingomonadales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WH3_k127_5977763_7	1248917.ANFX01000021_gene1671	6.811e-110	357.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2TQZM@28211|Alphaproteobacteria,2K19Z@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
WH3_k127_5977763_8	1479239.JQMU01000001_gene1649	1.974e-58	205.0	2AMZ5@1|root,31CWB@2|Bacteria,1N5R3@1224|Proteobacteria,2UDB9@28211|Alphaproteobacteria,2K669@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_5977763_4	1479239.JQMU01000001_gene1648	1.282e-150	478.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,2K0YX@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC-type (Unclassified) transport system, ATPase component	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
WH3_k127_5977763_1	1479239.JQMU01000001_gene1647	1.023e-264	823.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,2K182@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WH3_k127_5977763_5	1479239.JQMU01000001_gene1646	1.117e-146	466.0	COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,2K0S8@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ctrA	-	-	ko:K13584	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH3_k127_5977763_10	279238.Saro_0304	3.431e-07	52.0	COG2197@1|root,COG2197@2|Bacteria,1QYDG@1224|Proteobacteria,2TXPD@28211|Alphaproteobacteria,2KEID@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WH3_k127_5997668_1	1479239.JQMU01000001_gene2171	6.206e-112	373.0	2C7BT@1|root,33MZ9@2|Bacteria,1NMQ4@1224|Proteobacteria,2UG5B@28211|Alphaproteobacteria,2K40I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
WH3_k127_5997668_0	1479239.JQMU01000001_gene2172	8.108e-145	460.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria,2K0A2@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Acetoacetyl-CoA reductase	phbB	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
WH3_k127_6004415_2	1122970.AUHC01000012_gene899	5.825e-11	62.0	COG3735@1|root,COG3735@2|Bacteria,1NURR@1224|Proteobacteria,2URIH@28211|Alphaproteobacteria,2KDGP@204457|Sphingomonadales	204457|Sphingomonadales	S	TraB family	-	-	-	-	-	-	-	-	-	-	-	-	TraB
WH3_k127_6004415_0	1479239.JQMU01000001_gene1527	3.452e-161	512.0	COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,2TRY2@28211|Alphaproteobacteria,2K94R@204457|Sphingomonadales	204457|Sphingomonadales	I	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WH3_k127_6004415_1	1248917.ANFX01000008_gene294	2.896e-151	482.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TQY4@28211|Alphaproteobacteria,2K117@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WH3_k127_6029129_6	1248917.ANFX01000035_gene2000	7.677e-103	339.0	COG3757@1|root,COG3757@2|Bacteria,1N792@1224|Proteobacteria,2TVI6@28211|Alphaproteobacteria,2K4F7@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl hydrolases family 25	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
WH3_k127_6029129_7	1479239.JQMU01000001_gene1779	1.529e-102	335.0	COG5328@1|root,COG5328@2|Bacteria,1RA93@1224|Proteobacteria,2U741@28211|Alphaproteobacteria,2K40E@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0262 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0262
WH3_k127_6029129_0	1479239.JQMU01000001_gene1778	4.806e-294	907.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,2K1TQ@204457|Sphingomonadales	204457|Sphingomonadales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WH3_k127_6029129_1	1479239.JQMU01000001_gene382	1.665e-237	735.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2K0DU@204457|Sphingomonadales	204457|Sphingomonadales	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
WH3_k127_6029129_3	1248917.ANFX01000040_gene767	8.951e-124	402.0	COG2267@1|root,COG2267@2|Bacteria,1QWE3@1224|Proteobacteria,2UDWQ@28211|Alphaproteobacteria,2K630@204457|Sphingomonadales	204457|Sphingomonadales	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WH3_k127_6029129_4	1479239.JQMU01000001_gene384	2.259e-110	359.0	COG0346@1|root,COG0346@2|Bacteria,1RAC9@1224|Proteobacteria,2U65N@28211|Alphaproteobacteria,2K485@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH3_k127_6029129_5	1122970.AUHC01000002_gene1439	3.46e-110	358.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2TR4Z@28211|Alphaproteobacteria,2K1XE@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the WrbA family	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
WH3_k127_6029129_2	1479239.JQMU01000001_gene386	8.289e-175	549.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U1C8@28211|Alphaproteobacteria,2K3AZ@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_6049964_0	1479239.JQMU01000001_gene2327	0.0	1007.0	COG1028@1|root,COG1028@2|Bacteria,1R6F3@1224|Proteobacteria,2U1Z9@28211|Alphaproteobacteria,2K0Y6@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WH3_k127_6060329_1	1122970.AUHC01000001_gene500	1.342e-168	533.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,2K0IY@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WH3_k127_6060329_2	1479239.JQMU01000001_gene2720	5.411e-168	535.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,2K0BU@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WH3_k127_6060329_3	1479239.JQMU01000001_gene2721	9.015e-101	331.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2TQWQ@28211|Alphaproteobacteria,2K0W5@204457|Sphingomonadales	204457|Sphingomonadales	S	synthesis repressor PhaR	phaR	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
WH3_k127_6060329_0	1479239.JQMU01000001_gene2722	1.428e-206	643.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,2K1F1@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
WH3_k127_6066051_1	1248917.ANFX01000007_gene23	5.915e-56	196.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria,2K57J@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WH3_k127_6066051_0	1479239.JQMU01000001_gene1955	2.216e-120	393.0	COG5343@1|root,COG5343@2|Bacteria,1N821@1224|Proteobacteria,2UF3V@28211|Alphaproteobacteria,2K4R7@204457|Sphingomonadales	204457|Sphingomonadales	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
WH3_k127_6066051_2	1248917.ANFX01000007_gene25	7.638e-35	136.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,2K6RG@204457|Sphingomonadales	204457|Sphingomonadales	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
WH3_k127_6088132_0	1248917.ANFX01000014_gene1312	2.225e-222	706.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,2K1CR@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_6088132_2	1479239.JQMU01000001_gene1001	3.498e-147	470.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2TTMB@28211|Alphaproteobacteria,2KCQQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WH3_k127_6088132_1	1479239.JQMU01000001_gene1000	3.607e-220	692.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria,2JZW6@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_609439_1	1479239.JQMU01000001_gene2765	4.868e-211	659.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,2TR6M@28211|Alphaproteobacteria,2K17V@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
WH3_k127_609439_3	1479239.JQMU01000001_gene2764	8.214e-106	347.0	COG3714@1|root,COG3714@2|Bacteria,1RFIR@1224|Proteobacteria,2U8S6@28211|Alphaproteobacteria,2K4YA@204457|Sphingomonadales	204457|Sphingomonadales	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
WH3_k127_609439_0	1479239.JQMU01000001_gene2763	0.0	1676.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,2K02J@204457|Sphingomonadales	204457|Sphingomonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WH3_k127_609439_2	1479239.JQMU01000001_gene2762	1.343e-159	518.0	COG0457@1|root,COG0457@2|Bacteria,1Q7UR@1224|Proteobacteria,2U8BX@28211|Alphaproteobacteria,2K0N1@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_609439_4	1479239.JQMU01000001_gene2760	5.683e-73	246.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,2K1H4@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WH3_k127_6108541_3	1479239.JQMU01000001_gene1869	5.198e-69	238.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2K464@204457|Sphingomonadales	204457|Sphingomonadales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WH3_k127_6108541_0	1479239.JQMU01000001_gene1868	1.047e-120	391.0	COG5590@1|root,COG5590@2|Bacteria,1MW25@1224|Proteobacteria,2U9ST@28211|Alphaproteobacteria,2K3VY@204457|Sphingomonadales	204457|Sphingomonadales	S	RpsU-divergently transcribed	-	-	-	ko:K18587	-	-	-	-	ko00000	-	-	-	COQ9
WH3_k127_6108541_1	1479239.JQMU01000001_gene1867	5.534e-101	333.0	COG0666@1|root,COG0666@2|Bacteria,1RFFD@1224|Proteobacteria,2U8T6@28211|Alphaproteobacteria,2K4S6@204457|Sphingomonadales	204457|Sphingomonadales	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
WH3_k127_6108541_2	1479239.JQMU01000001_gene1866	6.192e-101	331.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria,2K4RS@204457|Sphingomonadales	204457|Sphingomonadales	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WH3_k127_6132236_7	1479239.JQMU01000001_gene1686	7.75e-59	204.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,2K1HB@204457|Sphingomonadales	204457|Sphingomonadales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WH3_k127_6132236_5	1248917.ANFX01000029_gene2689	1.105e-140	449.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria,2K1F9@204457|Sphingomonadales	204457|Sphingomonadales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
WH3_k127_6132236_6	1479239.JQMU01000001_gene1683	4.871e-68	241.0	COG5349@1|root,COG5349@2|Bacteria,1MZDD@1224|Proteobacteria,2UCM4@28211|Alphaproteobacteria,2K5QN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
WH3_k127_6132236_1	1479239.JQMU01000001_gene1682	2.432e-288	892.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,2JZZ0@204457|Sphingomonadales	204457|Sphingomonadales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WH3_k127_6132236_8	1479239.JQMU01000001_gene1681	1.032e-41	154.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria,2K617@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WH3_k127_6132236_3	1248917.ANFX01000029_gene2685	4.245e-161	510.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,2K2A5@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WH3_k127_6132236_4	1248917.ANFX01000029_gene2684	1.806e-150	484.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,2K080@204457|Sphingomonadales	204457|Sphingomonadales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
WH3_k127_6132236_0	1248917.ANFX01000029_gene2683	7.04e-321	985.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria,2K1BA@204457|Sphingomonadales	204457|Sphingomonadales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
WH3_k127_6132236_2	1479239.JQMU01000001_gene1676	1.385e-215	676.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria,2K0N6@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WH3_k127_6144110_5	1248916.ANFY01000008_gene2113	5.629e-22	107.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane
WH3_k127_6144110_1	1248916.ANFY01000008_gene2114	1.763e-110	369.0	COG1763@1|root,COG1763@2|Bacteria,1QUQC@1224|Proteobacteria,2TXUG@28211|Alphaproteobacteria,2K640@204457|Sphingomonadales	204457|Sphingomonadales	H	Mo-molybdopterin cofactor biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6144110_3	1248917.ANFX01000013_gene1435	2.065e-45	175.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria	1224|Proteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	IV02_00930	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
WH3_k127_6144110_2	68170.KL590489_gene10403	6.851e-78	271.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	ATPgrasp_ST,GshA
WH3_k127_6144110_0	1545915.JROG01000004_gene2067	2.036e-218	682.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,2K18V@204457|Sphingomonadales	204457|Sphingomonadales	C	Transketolase, thiamine diphosphate binding domain	-	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_N
WH3_k127_6154997_0	1479239.JQMU01000001_gene2440	0.0	1095.0	COG1305@1|root,COG1305@2|Bacteria,1R5Q7@1224|Proteobacteria,2U24E@28211|Alphaproteobacteria,2K21Z@204457|Sphingomonadales	204457|Sphingomonadales	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,TPR_16,TPR_8,Transglut_core
WH3_k127_6154997_2	1479239.JQMU01000001_gene2441	1.843e-172	542.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria,2K0D0@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WH3_k127_6154997_7	1197906.CAJQ02000003_gene3219	1.019e-05	53.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WH3_k127_6154997_6	1479239.JQMU01000001_gene2442	2.018e-22	102.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VEGK@28211|Alphaproteobacteria,2K7UE@204457|Sphingomonadales	204457|Sphingomonadales	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
WH3_k127_6154997_3	1479239.JQMU01000001_gene2443	1.085e-147	473.0	COG1530@1|root,COG1530@2|Bacteria,1RC15@1224|Proteobacteria,2U5PB@28211|Alphaproteobacteria,2K2AZ@204457|Sphingomonadales	204457|Sphingomonadales	J	ribonuclease E activity	-	-	-	-	-	-	-	-	-	-	-	-	RNase_E_G
WH3_k127_6154997_4	1545915.JROG01000001_gene515	1.746e-68	237.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,2K3WJ@204457|Sphingomonadales	204457|Sphingomonadales	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WH3_k127_6154997_5	1044.EH31_07485	1.141e-46	169.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,2K5VJ@204457|Sphingomonadales	204457|Sphingomonadales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WH3_k127_6154997_1	1248917.ANFX01000017_gene2535	1.763e-306	951.0	COG4206@1|root,COG4206@2|Bacteria,1MXFM@1224|Proteobacteria,2TWYV@28211|Alphaproteobacteria,2K14T@204457|Sphingomonadales	204457|Sphingomonadales	H	Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_617410_3	1479239.JQMU01000001_gene2111	2.346e-78	263.0	COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,2K0A1@204457|Sphingomonadales	204457|Sphingomonadales	S	GcrA cell cycle regulator	-	-	-	ko:K13583	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	GcrA
WH3_k127_617410_1	383381.EH30_09335	5.644e-150	479.0	COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,2U5G9@28211|Alphaproteobacteria,2JZWU@204457|Sphingomonadales	204457|Sphingomonadales	M	salt-induced outer membrane protein	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
WH3_k127_617410_2	1479239.JQMU01000001_gene2108	3.678e-131	420.0	COG4262@1|root,COG4262@2|Bacteria,1P1G3@1224|Proteobacteria,2TQSR@28211|Alphaproteobacteria,2K07Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
WH3_k127_617410_0	1479239.JQMU01000001_gene2107	0.0	1084.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,2K0IJ@204457|Sphingomonadales	204457|Sphingomonadales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WH3_k127_6183710_2	1479239.JQMU01000001_gene2604	2.609e-86	287.0	COG3618@1|root,COG3618@2|Bacteria,1MVG0@1224|Proteobacteria,2TRU9@28211|Alphaproteobacteria,2KD7H@204457|Sphingomonadales	204457|Sphingomonadales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WH3_k127_6183710_0	1479239.JQMU01000001_gene2605	1.951e-130	421.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria,2K414@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
WH3_k127_6183710_1	1248917.ANFX01000008_gene378	1.13e-125	403.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,2K1S1@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
WH3_k127_6221712_0	1479239.JQMU01000001_gene199	1.375e-109	357.0	COG1028@1|root,COG1028@2|Bacteria,1MX8B@1224|Proteobacteria,2U26N@28211|Alphaproteobacteria,2K4EG@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH3_k127_6221712_2	1248917.ANFX01000030_gene493	2.803e-49	182.0	2EHEF@1|root,33B6D@2|Bacteria,1NM8N@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6221712_1	1479239.JQMU01000001_gene198	5.317e-68	231.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria,2K1YS@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
WH3_k127_6266022_1	1479239.JQMU01000001_gene973	6.416e-163	569.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K0KA@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
WH3_k127_6266022_2	1479239.JQMU01000001_gene974	3.458e-129	418.0	COG0697@1|root,COG0697@2|Bacteria,1RC7K@1224|Proteobacteria,2U5C2@28211|Alphaproteobacteria,2K1KG@204457|Sphingomonadales	204457|Sphingomonadales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
WH3_k127_6266022_0	1479239.JQMU01000001_gene975	0.0	1718.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,2K0CP@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WH3_k127_6266022_3	1479239.JQMU01000001_gene976	1.653e-54	200.0	COG0607@1|root,COG0607@2|Bacteria,1N2R7@1224|Proteobacteria,2U9G7@28211|Alphaproteobacteria,2K4M8@204457|Sphingomonadales	204457|Sphingomonadales	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WH3_k127_6266022_4	1479239.JQMU01000001_gene978	1.344e-44	162.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,2K0Y3@204457|Sphingomonadales	204457|Sphingomonadales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WH3_k127_6271198_1	1248917.ANFX01000013_gene1516	2.571e-73	248.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,2K4E6@204457|Sphingomonadales	204457|Sphingomonadales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
WH3_k127_6271198_0	1545915.JROG01000009_gene2680	1.458e-220	695.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,2K6JI@204457|Sphingomonadales	204457|Sphingomonadales	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_8,Trans_reg_C
WH3_k127_6271198_4	384765.SIAM614_20680	1.909e-29	124.0	COG1942@1|root,COG1942@2|Bacteria,1NBW3@1224|Proteobacteria,2UHFK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
WH3_k127_6271198_3	570967.JMLV01000003_gene2218	1.119e-42	158.0	COG1917@1|root,COG1917@2|Bacteria,1RHHY@1224|Proteobacteria,2U9Y9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WH3_k127_6271198_2	1248917.ANFX01000013_gene1472	8.138e-44	160.0	COG1024@1|root,COG1024@2|Bacteria,1N4N7@1224|Proteobacteria,2TS6T@28211|Alphaproteobacteria,2K1V0@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH3_k127_6294342_0	1479239.JQMU01000001_gene2528	6.949e-182	572.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,2TRU5@28211|Alphaproteobacteria,2K20A@204457|Sphingomonadales	204457|Sphingomonadales	EI	Allophanate hydrolase subunit 2	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
WH3_k127_6294342_1	1479239.JQMU01000001_gene2529	8.944e-99	327.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TR00@28211|Alphaproteobacteria,2K2BN@204457|Sphingomonadales	204457|Sphingomonadales	J	Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
WH3_k127_632560_0	1479239.JQMU01000001_gene1399	2.472e-276	852.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2K0MN@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WH3_k127_640789_5	1248917.ANFX01000013_gene1556	3.665e-59	207.0	COG1725@1|root,COG1725@2|Bacteria,1MZG9@1224|Proteobacteria,2UBQ4@28211|Alphaproteobacteria,2K632@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
WH3_k127_640789_6	1122970.AUHC01000011_gene2783	4.098e-47	170.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria,2K633@204457|Sphingomonadales	204457|Sphingomonadales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WH3_k127_640789_0	1479239.JQMU01000001_gene1241	6.429e-282	874.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2U43Z@28211|Alphaproteobacteria,2K2RG@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
WH3_k127_640789_3	1479239.JQMU01000001_gene1242	2.941e-103	347.0	2AKT1@1|root,31BK2@2|Bacteria,1NXBB@1224|Proteobacteria,2UTRK@28211|Alphaproteobacteria,2K5KP@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WH3_k127_640789_4	1479239.JQMU01000001_gene1243	4.271e-89	295.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4P6@204457|Sphingomonadales	204457|Sphingomonadales	O	conserved domain frequently associated with peptide methionine sulfoxide reductase	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
WH3_k127_640789_1	1479239.JQMU01000001_gene1244	2.187e-270	835.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TRWW@28211|Alphaproteobacteria,2K1ZZ@204457|Sphingomonadales	204457|Sphingomonadales	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_640789_2	1479239.JQMU01000001_gene1245	2.172e-210	659.0	COG1668@1|root,COG1668@2|Bacteria,1MWAS@1224|Proteobacteria,2TU2K@28211|Alphaproteobacteria,2K1E9@204457|Sphingomonadales	204457|Sphingomonadales	CP	ABC-type Na efflux pump, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WH3_k127_6463690_2	1479239.JQMU01000001_gene1308	1.363e-115	375.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,2K0YD@204457|Sphingomonadales	204457|Sphingomonadales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
WH3_k127_6463690_1	1248917.ANFX01000043_gene2721	3.86e-171	550.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TR81@28211|Alphaproteobacteria,2K0CM@204457|Sphingomonadales	204457|Sphingomonadales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WH3_k127_6463690_0	1479239.JQMU01000001_gene1310	2.014e-243	755.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,2K0I4@204457|Sphingomonadales	204457|Sphingomonadales	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WH3_k127_6463690_3	1479239.JQMU01000001_gene1311	3.587e-102	334.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2U8YK@28211|Alphaproteobacteria,2KD5N@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WH3_k127_6485256_6	694427.Palpr_2674	2.906e-09	61.0	COG4980@1|root,COG4980@2|Bacteria,4NW56@976|Bacteroidetes,2FZ4H@200643|Bacteroidia	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
WH3_k127_6485256_5	1096930.L284_20125	1.593e-09	59.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,2K0II@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WH3_k127_6485256_0	1479239.JQMU01000001_gene2630	2.759e-288	899.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2U08D@28211|Alphaproteobacteria,2KD2V@204457|Sphingomonadales	204457|Sphingomonadales	E	Prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WH3_k127_6485256_3	1248917.ANFX01000008_gene352	1.837e-46	171.0	COG1605@1|root,COG1605@2|Bacteria,1N4KD@1224|Proteobacteria,2UFR2@28211|Alphaproteobacteria,2K65F@204457|Sphingomonadales	204457|Sphingomonadales	E	chorismate mutase	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	CM_2
WH3_k127_6485256_2	383381.EH30_05550	1.707e-102	336.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2U7JU@28211|Alphaproteobacteria,2K5ZW@204457|Sphingomonadales	204457|Sphingomonadales	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
WH3_k127_6485256_1	1479239.JQMU01000001_gene2633	1.503e-123	396.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,2K0KZ@204457|Sphingomonadales	204457|Sphingomonadales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WH3_k127_6485256_4	1248917.ANFX01000008_gene347	2.185e-39	147.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,2JZUG@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GIY-YIG,SpoU_methylase
WH3_k127_6499676_3	1248917.ANFX01000019_gene2396	1.553e-56	197.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,2JZUH@204457|Sphingomonadales	204457|Sphingomonadales	G	in Escherichia coli this protein forms a dimer and binds manganese	glpX	-	3.1.3.11,3.1.3.37	ko:K11532	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
WH3_k127_6499676_6	383381.EH30_13655	4.652e-20	96.0	2DT2E@1|root,33ID6@2|Bacteria,1NIYV@1224|Proteobacteria,2UX3I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6499676_0	1479239.JQMU01000001_gene2329	5.167e-259	798.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TQRA@28211|Alphaproteobacteria,2K01U@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_6499676_1	1479239.JQMU01000001_gene2330	4.308e-224	708.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TSKH@28211|Alphaproteobacteria,2K0KB@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_6499676_2	383381.EH30_08390	1.217e-114	376.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2TTEP@28211|Alphaproteobacteria,2K2P6@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WH3_k127_6499676_4	1479239.JQMU01000001_gene1506	7.073e-46	166.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,2K0MQ@204457|Sphingomonadales	204457|Sphingomonadales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WH3_k127_6503136_3	1479239.JQMU01000001_gene2391	4.435e-173	543.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0TH@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WH3_k127_6503136_1	1479239.JQMU01000001_gene2390	1.508e-309	953.0	COG0492@1|root,COG0664@1|root,COG0492@2|Bacteria,COG0664@2|Bacteria,1MVX2@1224|Proteobacteria,2TQN3@28211|Alphaproteobacteria,2K073@204457|Sphingomonadales	204457|Sphingomonadales	O	reductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
WH3_k127_6503136_5	1122970.AUHC01000005_gene1974	1.89e-47	172.0	2AY5B@1|root,31Q79@2|Bacteria,1NF1Q@1224|Proteobacteria,2UH21@28211|Alphaproteobacteria,2K6I2@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6503136_0	1479239.JQMU01000001_gene2388	0.0	1022.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,2JZZG@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WH3_k127_6503136_4	1219035.NT2_02_02250	8.497e-112	370.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,2JZVH@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K14981	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WH3_k127_6503136_2	1479239.JQMU01000001_gene2386	2.814e-280	869.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2TS69@28211|Alphaproteobacteria,2K1JA@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
WH3_k127_6503519_3	383381.EH30_08510	1.223e-52	186.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TTJP@28211|Alphaproteobacteria,2K07M@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
WH3_k127_6503519_0	1248917.ANFX01000032_gene894	0.0	1093.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2K1IG@204457|Sphingomonadales	204457|Sphingomonadales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WH3_k127_6503519_1	1479239.JQMU01000001_gene712	2.775e-183	577.0	COG0111@1|root,COG0111@2|Bacteria,1R65M@1224|Proteobacteria,2TTY3@28211|Alphaproteobacteria,2K1D4@204457|Sphingomonadales	204457|Sphingomonadales	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WH3_k127_6503519_2	1122970.AUHC01000008_gene84	1.124e-117	383.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,2K19T@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
WH3_k127_6549333_4	1479239.JQMU01000001_gene1788	1.114e-45	169.0	2EG1C@1|root,339TC@2|Bacteria,1NGB5@1224|Proteobacteria,2UK68@28211|Alphaproteobacteria,2K7K2@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6549333_2	1479239.JQMU01000001_gene1789	7.779e-109	353.0	COG1733@1|root,COG1733@2|Bacteria,1RIZT@1224|Proteobacteria,2U7SS@28211|Alphaproteobacteria,2K4MD@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
WH3_k127_6549333_0	1479239.JQMU01000001_gene1790	0.0	1058.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria,2K0QS@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
WH3_k127_6549333_3	1479239.JQMU01000001_gene1791	5.913e-104	345.0	2AK5K@1|root,31AVG@2|Bacteria,1REG7@1224|Proteobacteria,2U8E6@28211|Alphaproteobacteria,2K5AP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	-
WH3_k127_6549333_1	1479239.JQMU01000001_gene1792	4.88e-299	919.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria,2K1A3@204457|Sphingomonadales	204457|Sphingomonadales	O	ATPase with chaperone activity	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WH3_k127_6554151_1	1248917.ANFX01000016_gene2485	1.759e-183	577.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,2TVJ1@28211|Alphaproteobacteria,2K2D2@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WH3_k127_6554151_0	1122970.AUHC01000004_gene2248	2.08e-263	816.0	COG2211@1|root,COG2211@2|Bacteria,1MX4Z@1224|Proteobacteria,2TTX5@28211|Alphaproteobacteria,2K0AH@204457|Sphingomonadales	204457|Sphingomonadales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
WH3_k127_6585830_0	1248917.ANFX01000030_gene549	9.449e-195	611.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,2K17G@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
WH3_k127_6585830_4	1479239.JQMU01000001_gene149	1.255e-73	251.0	COG3063@1|root,COG3063@2|Bacteria,1R17W@1224|Proteobacteria,2TYY0@28211|Alphaproteobacteria,2KEPF@204457|Sphingomonadales	204457|Sphingomonadales	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WH3_k127_6585830_2	1248917.ANFX01000030_gene551	1.985e-82	287.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,2K4S3@204457|Sphingomonadales	204457|Sphingomonadales	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
WH3_k127_6585830_1	1479239.JQMU01000001_gene147	1.265e-166	531.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2U5X1@28211|Alphaproteobacteria,2JZVT@204457|Sphingomonadales	204457|Sphingomonadales	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WH3_k127_6585830_3	1479239.JQMU01000001_gene146	4.71e-78	262.0	COG1988@1|root,COG1988@2|Bacteria,1RA9E@1224|Proteobacteria,2U5TK@28211|Alphaproteobacteria,2K3A3@204457|Sphingomonadales	204457|Sphingomonadales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
WH3_k127_6590198_1	1479239.JQMU01000001_gene1579	9.223e-128	408.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2K2HH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_6590198_0	1248917.ANFX01000019_gene2338	1.489e-294	908.0	COG4638@1|root,COG4638@2|Bacteria,1MXZN@1224|Proteobacteria,2TQRJ@28211|Alphaproteobacteria,2K131@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
WH3_k127_6590198_2	1479239.JQMU01000001_gene1578	2.568e-64	220.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2TUZ7@28211|Alphaproteobacteria,2KD4G@204457|Sphingomonadales	204457|Sphingomonadales	C	FAD binding domain	-	-	1.3.99.4	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09884	RC00991	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
WH3_k127_6606204_0	1479239.JQMU01000001_gene1508	1.841e-159	503.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,2K0WC@204457|Sphingomonadales	204457|Sphingomonadales	G	COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
WH3_k127_6606204_2	555793.WSK_1679	2.483e-89	308.0	COG2207@1|root,COG2207@2|Bacteria,1N6FY@1224|Proteobacteria,2UEU0@28211|Alphaproteobacteria,2K6FI@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WH3_k127_6606204_1	1248917.ANFX01000021_gene1653	9.128e-105	341.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,2K0MQ@204457|Sphingomonadales	204457|Sphingomonadales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WH3_k127_6619048_1	1044.EH31_05375	1.408e-100	333.0	COG1629@1|root,COG2931@1|root,COG1629@2|Bacteria,COG2931@2|Bacteria,1QTVF@1224|Proteobacteria,2TW2N@28211|Alphaproteobacteria,2KE9C@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
WH3_k127_6619048_0	1479239.JQMU01000001_gene1932	0.0	1342.0	COG2866@1|root,COG2866@2|Bacteria,1N9W9@1224|Proteobacteria,2U2SA@28211|Alphaproteobacteria,2K2QH@204457|Sphingomonadales	204457|Sphingomonadales	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	BPL_N,Peptidase_M14
WH3_k127_6652738_0	1479239.JQMU01000001_gene2326	8.459e-122	395.0	COG0365@1|root,COG0604@1|root,COG1024@1|root,COG0365@2|Bacteria,COG0604@2|Bacteria,COG1024@2|Bacteria,1MXIK@1224|Proteobacteria,2U43I@28211|Alphaproteobacteria,2K2UF@204457|Sphingomonadales	204457|Sphingomonadales	CI	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,ECH_1
WH3_k127_6652738_3	1248917.ANFX01000022_gene663	1.586e-93	309.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2U57X@28211|Alphaproteobacteria,2K3W2@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
WH3_k127_6652738_2	1479239.JQMU01000001_gene2323	1.377e-95	327.0	2DI57@1|root,3022D@2|Bacteria,1NCDE@1224|Proteobacteria,2UGGV@28211|Alphaproteobacteria,2K770@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6652738_1	1248917.ANFX01000036_gene1903	4.649e-120	393.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,2K1GF@204457|Sphingomonadales	204457|Sphingomonadales	P	Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WH3_k127_6652738_4	1248917.ANFX01000036_gene1904	6.187e-06	53.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,2K0WB@204457|Sphingomonadales	204457|Sphingomonadales	E	cystathionine beta-lyase	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WH3_k127_6713770_0	1479239.JQMU01000001_gene1667	0.0	1099.0	COG3544@1|root,COG3544@2|Bacteria,1NTI3@1224|Proteobacteria,2UMCM@28211|Alphaproteobacteria,2K3DW@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
WH3_k127_6713770_2	1479239.JQMU01000001_gene1666	1.181e-178	563.0	COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,2UBDH@28211|Alphaproteobacteria,2K2BR@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
WH3_k127_6713770_3	1479239.JQMU01000001_gene1665	9.243e-25	106.0	2BS0M@1|root,32M16@2|Bacteria,1P8T8@1224|Proteobacteria,2UYZ9@28211|Alphaproteobacteria,2KBVN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6713770_1	1479239.JQMU01000001_gene1664	5.005e-208	653.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2K1KW@204457|Sphingomonadales	204457|Sphingomonadales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WH3_k127_6725721_4	1479239.JQMU01000001_gene2238	2.788e-152	485.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria,2K03P@204457|Sphingomonadales	204457|Sphingomonadales	NU	type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
WH3_k127_6725721_2	1479239.JQMU01000001_gene2239	7.089e-172	543.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria,2K0B5@204457|Sphingomonadales	204457|Sphingomonadales	U	pilus assembly protein TadB	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
WH3_k127_6725721_1	1479239.JQMU01000001_gene2240	7.533e-256	791.0	COG2204@1|root,COG4963@1|root,COG2204@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,2K0BT@204457|Sphingomonadales	204457|Sphingomonadales	TU	Flp pilus assembly protein, ATPase CpaE	cpaE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CbiA,ParA
WH3_k127_6725721_5	1479239.JQMU01000001_gene2241	7.941e-113	372.0	COG5461@1|root,COG5461@2|Bacteria,1REYP@1224|Proteobacteria,2U8J3@28211|Alphaproteobacteria,2K5AY@204457|Sphingomonadales	204457|Sphingomonadales	N	Pilus assembly protein CpaD	cpaD	-	-	ko:K02281	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Pilus_CpaD
WH3_k127_6725721_0	1479239.JQMU01000001_gene2242	9.921e-303	935.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,2K0ZQ@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the GSP D family	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
WH3_k127_6725721_3	1479239.JQMU01000001_gene2243	2.043e-164	524.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,2K08W@204457|Sphingomonadales	204457|Sphingomonadales	U	Pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
WH3_k127_6725721_6	1479239.JQMU01000001_gene2244	2.761e-39	148.0	COG4960@1|root,COG4960@2|Bacteria,1RAYG@1224|Proteobacteria,2UJT9@28211|Alphaproteobacteria,2K6EK@204457|Sphingomonadales	204457|Sphingomonadales	OU	peptidase	cpaA	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
WH3_k127_6747198_4	1479239.JQMU01000001_gene1799	1.377e-149	477.0	COG3000@1|root,COG3000@2|Bacteria,1R646@1224|Proteobacteria,2U1PJ@28211|Alphaproteobacteria,2K0N0@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH3_k127_6747198_9	1410676.JNKL01000008_gene44	1.342e-22	110.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y5XC@135624|Aeromonadales	135624|Aeromonadales	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
WH3_k127_6747198_2	1248917.ANFX01000013_gene1469	1.283e-250	775.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2TQXW@28211|Alphaproteobacteria,2K1W9@204457|Sphingomonadales	204457|Sphingomonadales	I	de-polymerase	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
WH3_k127_6747198_1	1248917.ANFX01000013_gene1468	0.0	1000.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2K0VT@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WH3_k127_6747198_0	1248917.ANFX01000013_gene1467	0.0	1217.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,2TRU4@28211|Alphaproteobacteria,2K02W@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M13	-	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
WH3_k127_6747198_6	1122970.AUHC01000012_gene960	6.167e-140	448.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,2K0R1@204457|Sphingomonadales	204457|Sphingomonadales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WH3_k127_6747198_8	1248917.ANFX01000013_gene1465	2.555e-30	122.0	2BRBX@1|root,32KAH@2|Bacteria,1PP9J@1224|Proteobacteria,2V1SK@28211|Alphaproteobacteria,2KBZ5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6747198_3	1248917.ANFX01000013_gene1464	4.455e-197	615.0	COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,2TU1E@28211|Alphaproteobacteria,2K01F@204457|Sphingomonadales	204457|Sphingomonadales	E	Phenylalanine-4-hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
WH3_k127_6747198_5	1248917.ANFX01000013_gene1463	1.554e-148	473.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,2K0KF@204457|Sphingomonadales	204457|Sphingomonadales	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
WH3_k127_6747198_7	1248917.ANFX01000013_gene1462	1.644e-105	344.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2TV0U@28211|Alphaproteobacteria,2K2J9@204457|Sphingomonadales	204457|Sphingomonadales	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153	ko:K09709	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09282	RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
WH3_k127_6767722_0	1479239.JQMU01000001_gene1043	1.639e-130	418.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2TSIA@28211|Alphaproteobacteria,2K0U7@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
WH3_k127_6767722_2	1248917.ANFX01000050_gene636	3.11e-23	101.0	COG5508@1|root,COG5508@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1674)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1674
WH3_k127_6767722_1	1479239.JQMU01000001_gene1045	1.445e-88	291.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,2K088@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_6780170_0	1248917.ANFX01000033_gene739	1.348e-304	934.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH3_k127_6780170_4	1479239.JQMU01000001_gene1728	5.167e-123	398.0	COG0625@1|root,COG0625@2|Bacteria,1RJVR@1224|Proteobacteria,2U5SU@28211|Alphaproteobacteria,2K42G@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_C_3,GST_N_3
WH3_k127_6780170_3	1479239.JQMU01000001_gene1729	5.948e-178	561.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2TSN3@28211|Alphaproteobacteria,2JZYP@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WH3_k127_6780170_6	1123269.NX02_21130	7.052e-29	127.0	2DN0U@1|root,32UTB@2|Bacteria,1MZ2J@1224|Proteobacteria,2UHAI@28211|Alphaproteobacteria,2K24S@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6780170_2	1122970.AUHC01000010_gene1543	1.28e-188	597.0	28MAA@1|root,2ZAP0@2|Bacteria,1R5EZ@1224|Proteobacteria,2U43A@28211|Alphaproteobacteria,2JZVU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6780170_5	1248917.ANFX01000033_gene752	3.093e-55	194.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	MA20_14325	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
WH3_k127_6780170_1	1248917.ANFX01000033_gene751	1.329e-286	887.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,2K1B6@204457|Sphingomonadales	204457|Sphingomonadales	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
WH3_k127_678259_0	1248917.ANFX01000015_gene2604	6.877e-205	638.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria,2K026@204457|Sphingomonadales	204457|Sphingomonadales	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
WH3_k127_678259_1	1479239.JQMU01000001_gene2860	9.85e-97	318.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria,2K1P3@204457|Sphingomonadales	204457|Sphingomonadales	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
WH3_k127_6790124_1	1479239.JQMU01000001_gene2306	1.22e-140	455.0	COG0457@1|root,COG0457@2|Bacteria,1QNIE@1224|Proteobacteria,2TVQA@28211|Alphaproteobacteria,2K08T@204457|Sphingomonadales	204457|Sphingomonadales	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_19
WH3_k127_6790124_0	1479239.JQMU01000001_gene2305	5.203e-279	866.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,2K16V@204457|Sphingomonadales	204457|Sphingomonadales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WH3_k127_6790124_2	1479239.JQMU01000001_gene2304	8.282e-123	396.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,2K082@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WH3_k127_684310_1	1122970.AUHC01000001_gene706	6.194e-123	395.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria,2K1YS@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
WH3_k127_684310_2	1248917.ANFX01000030_gene495	6.906e-104	340.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,2K0UT@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WH3_k127_684310_5	1248917.ANFX01000030_gene496	6.821e-39	145.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria,2K5WV@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WH3_k127_684310_4	1248917.ANFX01000030_gene497	4.495e-64	227.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria,2K4F9@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WH3_k127_684310_0	1479239.JQMU01000001_gene194	5.313e-156	499.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2TU43@28211|Alphaproteobacteria,2K0C1@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
WH3_k127_684310_3	1479239.JQMU01000001_gene193	1.054e-74	251.0	COG0625@1|root,COG0625@2|Bacteria,1PA0Q@1224|Proteobacteria,2TVIC@28211|Alphaproteobacteria,2K4XA@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
WH3_k127_6909533_1	1479239.JQMU01000001_gene2542	2.985e-97	321.0	COG0259@1|root,COG0259@2|Bacteria,1RIAU@1224|Proteobacteria,2UBET@28211|Alphaproteobacteria,2K4DS@204457|Sphingomonadales	204457|Sphingomonadales	H	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Putative_PNPOx,Pyridox_oxase_2
WH3_k127_6909533_2	1479239.JQMU01000001_gene2543	2.76e-71	247.0	COG2199@1|root,COG3706@2|Bacteria,1QTJ3@1224|Proteobacteria,2V9R7@28211|Alphaproteobacteria,2KB5R@204457|Sphingomonadales	204457|Sphingomonadales	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WH3_k127_6909533_0	1248917.ANFX01000037_gene2099	9.459e-152	480.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2K0YK@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WH3_k127_6926069_2	1479239.JQMU01000001_gene2343	1.624e-93	308.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria,2K14F@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH3_k127_6926069_3	1248917.ANFX01000022_gene677	8.811e-57	202.0	2C7KN@1|root,336M6@2|Bacteria,1N4WC@1224|Proteobacteria,2UF5V@28211|Alphaproteobacteria,2KAPC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6926069_1	1122970.AUHC01000005_gene2013	2.083e-103	341.0	COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,2U1HF@28211|Alphaproteobacteria,2K4SR@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WH3_k127_6926069_0	1479239.JQMU01000001_gene2340	1.1e-232	722.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2TQVF@28211|Alphaproteobacteria,2K1Z2@204457|Sphingomonadales	204457|Sphingomonadales	L	ATPase related to the helicase subunit of the Holliday junction resolvase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
WH3_k127_6935718_3	1248917.ANFX01000008_gene315	5.591e-31	123.0	COG1524@1|root,COG1524@2|Bacteria,1N5SF@1224|Proteobacteria,2TU7V@28211|Alphaproteobacteria,2K15Z@204457|Sphingomonadales	204457|Sphingomonadales	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WH3_k127_6935718_0	1479239.JQMU01000001_gene2664	9.314e-215	669.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,2K213@204457|Sphingomonadales	204457|Sphingomonadales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WH3_k127_6935718_1	1479239.JQMU01000001_gene2665	1.376e-164	522.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria,2K3HZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH3_k127_6935718_2	1248917.ANFX01000008_gene312	9.893e-85	282.0	COG0563@1|root,COG0563@2|Bacteria,1N0HQ@1224|Proteobacteria,2UC20@28211|Alphaproteobacteria,2K52E@204457|Sphingomonadales	204457|Sphingomonadales	F	Adenylate kinase and related kinases	-	-	-	-	-	-	-	-	-	-	-	-	AAA
WH3_k127_6939077_8	1479239.JQMU01000001_gene649	1.097e-116	376.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,2U1WU@28211|Alphaproteobacteria,2K1HS@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WH3_k127_6939077_0	1479239.JQMU01000001_gene648	0.0	1682.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MU9K@1224|Proteobacteria,2TTUW@28211|Alphaproteobacteria,2K135@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_6939077_4	1479239.JQMU01000001_gene647	6.857e-176	562.0	COG2866@1|root,COG2866@2|Bacteria,1R490@1224|Proteobacteria,2U9Z3@28211|Alphaproteobacteria,2K5PY@204457|Sphingomonadales	204457|Sphingomonadales	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WH3_k127_6939077_12	1545915.JROG01000003_gene1626	3.45e-74	264.0	2BTV9@1|root,32P32@2|Bacteria,1REIU@1224|Proteobacteria,2U8I3@28211|Alphaproteobacteria,2K4FZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_6939077_14	1122970.AUHC01000008_gene144	3.115e-49	181.0	COG0640@1|root,COG0640@2|Bacteria,1R9HP@1224|Proteobacteria,2VC6B@28211|Alphaproteobacteria,2K57N@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
WH3_k127_6939077_3	1479239.JQMU01000001_gene2550	8.022e-278	863.0	COG0659@1|root,COG0659@2|Bacteria,1MX8F@1224|Proteobacteria,2U0IJ@28211|Alphaproteobacteria,2K0EC@204457|Sphingomonadales	204457|Sphingomonadales	P	Transporter	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2,Sulfate_transp
WH3_k127_6939077_7	1122970.AUHC01000008_gene146	2.242e-123	402.0	COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,2VEYE@28211|Alphaproteobacteria,2KCWE@204457|Sphingomonadales	204457|Sphingomonadales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
WH3_k127_6939077_13	1479239.JQMU01000001_gene2552	8.263e-52	186.0	COG0640@1|root,COG0640@2|Bacteria,1N3H4@1224|Proteobacteria,2UCAF@28211|Alphaproteobacteria,2K5XK@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
WH3_k127_6939077_10	1479239.JQMU01000001_gene826	4.155e-96	321.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,2K1CI@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WH3_k127_6939077_11	1479239.JQMU01000001_gene646	6.337e-90	297.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2K4AH@204457|Sphingomonadales	204457|Sphingomonadales	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WH3_k127_6939077_1	1479239.JQMU01000001_gene645	0.0	1345.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
WH3_k127_6939077_15	471854.Dfer_5190	2.536e-17	90.0	COG2068@1|root,COG2068@2|Bacteria,4NQNF@976|Bacteroidetes,47PUQ@768503|Cytophagia	976|Bacteroidetes	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WH3_k127_6939077_6	1479239.JQMU01000001_gene644	1.402e-156	500.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria,2K17D@204457|Sphingomonadales	204457|Sphingomonadales	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
WH3_k127_6939077_5	1248917.ANFX01000012_gene1773	4.222e-169	535.0	COG2382@1|root,COG2382@2|Bacteria,1QZM0@1224|Proteobacteria,2TY9P@28211|Alphaproteobacteria,2KEKJ@204457|Sphingomonadales	204457|Sphingomonadales	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
WH3_k127_6939077_9	1248917.ANFX01000012_gene1774	4.866e-103	338.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2TUMH@28211|Alphaproteobacteria,2K1HN@204457|Sphingomonadales	204457|Sphingomonadales	G	Aldolase	eda	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
WH3_k127_6939077_2	1479239.JQMU01000001_gene2187	0.0	1143.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,2TQNS@28211|Alphaproteobacteria,2K1X3@204457|Sphingomonadales	204457|Sphingomonadales	EG	Belongs to the IlvD Edd family	-	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
WH3_k127_6951678_1	1479239.JQMU01000001_gene2642	2.55e-59	207.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria,2K3W5@204457|Sphingomonadales	204457|Sphingomonadales	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
WH3_k127_6951678_0	1479239.JQMU01000001_gene2641	0.0	1095.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,2K0VR@204457|Sphingomonadales	204457|Sphingomonadales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4,Toprim_N,zf-CHC2
WH3_k127_6951678_2	1248917.ANFX01000008_gene342	3.751e-53	189.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,2K260@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WH3_k127_6953644_0	1248917.ANFX01000012_gene1901	1.292e-240	753.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,2K12C@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
WH3_k127_6990577_0	1248917.ANFX01000045_gene1293	1.515e-215	676.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,2K0JH@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
WH3_k127_6990577_1	1479239.JQMU01000001_gene872	8.802e-137	460.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,2K1Q4@204457|Sphingomonadales	204457|Sphingomonadales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WH3_k127_699381_2	1479239.JQMU01000001_gene2482	8.98e-81	271.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,2TUX2@28211|Alphaproteobacteria,2K1QD@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
WH3_k127_699381_1	1248917.ANFX01000037_gene2047	1.407e-165	529.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,2K00C@204457|Sphingomonadales	204457|Sphingomonadales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
WH3_k127_699381_0	1248917.ANFX01000037_gene2048	7.172e-193	602.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2K034@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WH3_k127_7003033_5	1479239.JQMU01000001_gene1156	2.916e-37	141.0	COG4872@1|root,COG4872@2|Bacteria,1N4JN@1224|Proteobacteria,2UE2X@28211|Alphaproteobacteria,2K8KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
WH3_k127_7003033_4	1248917.ANFX01000013_gene1437	9.958e-63	225.0	2ERHA@1|root,33J2S@2|Bacteria,1NH9V@1224|Proteobacteria,2UJWK@28211|Alphaproteobacteria,2K7PE@204457|Sphingomonadales	204457|Sphingomonadales	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
WH3_k127_7003033_1	1248917.ANFX01000013_gene1436	2.28e-158	507.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,2U972@28211|Alphaproteobacteria	28211|Alphaproteobacteria	HJ	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
WH3_k127_7003033_3	1248917.ANFX01000013_gene1435	2.643e-128	420.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria	1224|Proteobacteria	E	7 transmembrane helices usually fused to an inactive transglutaminase	IV02_00930	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
WH3_k127_7003033_0	1248917.ANFX01000013_gene1433	0.0	1296.0	COG4773@1|root,COG4773@2|Bacteria,1Q323@1224|Proteobacteria,2TW33@28211|Alphaproteobacteria,2K10M@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_7026874_1	1479239.JQMU01000001_gene728	0.0	1099.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K20D@204457|Sphingomonadales	204457|Sphingomonadales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
WH3_k127_7026874_5	1248917.ANFX01000032_gene983	7.212e-163	518.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,2K1YI@204457|Sphingomonadales	204457|Sphingomonadales	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
WH3_k127_7026874_10	1479239.JQMU01000001_gene726	1.932e-109	364.0	COG1802@1|root,COG1802@2|Bacteria,1N1X3@1224|Proteobacteria,2U5PS@28211|Alphaproteobacteria,2K3ZQ@204457|Sphingomonadales	204457|Sphingomonadales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WH3_k127_7026874_6	1479239.JQMU01000001_gene725	1.908e-155	495.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2TQQI@28211|Alphaproteobacteria,2K2HR@204457|Sphingomonadales	204457|Sphingomonadales	E	Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7026874_12	1479239.JQMU01000001_gene724	6.973e-88	291.0	COG3631@1|root,COG3631@2|Bacteria,1NQQJ@1224|Proteobacteria,2UP8A@28211|Alphaproteobacteria,2K3XV@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WH3_k127_7026874_14	1479239.JQMU01000001_gene723	1.584e-78	263.0	COG3631@1|root,COG3631@2|Bacteria,1RH51@1224|Proteobacteria,2UA2P@28211|Alphaproteobacteria,2K4MH@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WH3_k127_7026874_0	1122970.AUHC01000014_gene1152	0.0	1434.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U1C8@28211|Alphaproteobacteria,2K263@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_7026874_8	1122970.AUHC01000004_gene2331	3.251e-132	426.0	COG1051@1|root,COG1051@2|Bacteria,1QUPQ@1224|Proteobacteria,2TW3M@28211|Alphaproteobacteria,2K0RT@204457|Sphingomonadales	204457|Sphingomonadales	F	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WH3_k127_7026874_15	1248917.ANFX01000051_gene475	1.12e-59	210.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,2K55Y@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
WH3_k127_7026874_17	1479239.JQMU01000001_gene2071	8.811e-38	143.0	COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,2K5YQ@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
WH3_k127_7026874_16	1479239.JQMU01000001_gene2072	8.215e-51	183.0	COG5467@1|root,COG5467@2|Bacteria,1MZRN@1224|Proteobacteria,2UC1G@28211|Alphaproteobacteria,2K533@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1476
WH3_k127_7026874_4	1479239.JQMU01000001_gene2073	4.082e-200	625.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,2K1HA@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
WH3_k127_7026874_9	1479239.JQMU01000001_gene2074	1.15e-116	376.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,2JZWQ@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
WH3_k127_7026874_3	1479239.JQMU01000001_gene2076	2.282e-290	894.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TR6K@28211|Alphaproteobacteria,2K0IM@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WH3_k127_7026874_13	1479239.JQMU01000001_gene2077	4.467e-80	267.0	COG0824@1|root,COG0824@2|Bacteria,1RHB1@1224|Proteobacteria,2UATC@28211|Alphaproteobacteria,2K4SF@204457|Sphingomonadales	204457|Sphingomonadales	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,Acyl-ACP_TE
WH3_k127_7026874_2	1545915.JROG01000001_gene144	6.058e-294	908.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,2TU03@28211|Alphaproteobacteria,2K2W3@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer
WH3_k127_7026874_7	1479239.JQMU01000001_gene2080	2.181e-144	463.0	COG3239@1|root,COG3239@2|Bacteria,1RBD8@1224|Proteobacteria,2U5EY@28211|Alphaproteobacteria,2K2RH@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid desaturase	-	-	-	ko:K09836	ko00906,map00906	-	R05345,R07549,R07557,R07563,R07564,R07565,R07566,R07567,R07571,R07573	RC01900,RC01991	ko00000,ko00001	-	-	-	FA_desaturase
WH3_k127_7026874_11	1248917.ANFX01000051_gene462	6.14e-95	310.0	COG3000@1|root,COG3000@2|Bacteria,1RJ68@1224|Proteobacteria,2U9CS@28211|Alphaproteobacteria,2K3D1@204457|Sphingomonadales	204457|Sphingomonadales	I	hydroxylase	-	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
WH3_k127_7029483_0	1479239.JQMU01000001_gene1614	9.168e-295	912.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,1MW2M@1224|Proteobacteria,2TRIR@28211|Alphaproteobacteria,2K1G5@204457|Sphingomonadales	204457|Sphingomonadales	CP	Domain related to MnhB subunit of Na+/H+ antiporter	phaAB	-	-	ko:K05559	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
WH3_k127_7029483_2	1479239.JQMU01000001_gene1615	2.729e-53	194.0	COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,2UA52@28211|Alphaproteobacteria,2K58P@204457|Sphingomonadales	204457|Sphingomonadales	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	phaC	-	-	ko:K05560	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Oxidored_q2
WH3_k127_7029483_1	1479239.JQMU01000001_gene1616	1.217e-61	214.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,2K334@204457|Sphingomonadales	204457|Sphingomonadales	CP	Proton-conducting membrane transporter	phaD	-	-	ko:K05561	-	-	-	-	ko00000,ko02000	2.A.63.1	-	-	Proton_antipo_M
WH3_k127_7054146_2	1248917.ANFX01000007_gene17	3.795e-49	182.0	COG1310@1|root,COG1310@2|Bacteria,1NC23@1224|Proteobacteria,2UGM4@28211|Alphaproteobacteria,2K62I@204457|Sphingomonadales	204457|Sphingomonadales	L	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
WH3_k127_7054146_0	1479239.JQMU01000001_gene1960	6.158e-171	542.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,2K1VU@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WH3_k127_7054146_1	314225.ELI_01175	3.297e-129	414.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,2K1G6@204457|Sphingomonadales	204457|Sphingomonadales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
WH3_k127_7054831_3	1479239.JQMU01000001_gene1004	2.681e-05	51.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,2TV2E@28211|Alphaproteobacteria,2JZVQ@204457|Sphingomonadales	204457|Sphingomonadales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_3
WH3_k127_7054831_1	1248917.ANFX01000014_gene1310	0.0	1065.0	COG4206@1|root,COG4206@2|Bacteria,1R1WX@1224|Proteobacteria,2U0GK@28211|Alphaproteobacteria,2K1DC@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WH3_k127_7054831_0	1122970.AUHC01000015_gene2572	0.0	1421.0	COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2U2VU@28211|Alphaproteobacteria,2K27X@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_7054831_2	161528.ED21_30629	7.63e-33	126.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,2K1CR@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_7055764_1	1479239.JQMU01000001_gene616	3.908e-140	452.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,2TRW9@28211|Alphaproteobacteria,2K0J2@204457|Sphingomonadales	204457|Sphingomonadales	J	Hemolysin	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
WH3_k127_7055764_2	1479239.JQMU01000001_gene617	1.373e-34	140.0	2BR2H@1|root,32K09@2|Bacteria,1NW9X@1224|Proteobacteria,2US0J@28211|Alphaproteobacteria,2K5FU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7055764_0	1479239.JQMU01000001_gene618	1.307e-217	677.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,2K0G3@204457|Sphingomonadales	204457|Sphingomonadales	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WH3_k127_7059216_3	1479239.JQMU01000001_gene1964	3.985e-85	288.0	2DR92@1|root,33ARB@2|Bacteria,1QYNQ@1224|Proteobacteria,2TXT3@28211|Alphaproteobacteria,2KEJC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7059216_2	1122970.AUHC01000004_gene2199	1.089e-119	388.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2TRGG@28211|Alphaproteobacteria,2K1ZT@204457|Sphingomonadales	204457|Sphingomonadales	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
WH3_k127_7059216_0	1479239.JQMU01000001_gene1963	9.048e-142	451.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria,2K0W6@204457|Sphingomonadales	204457|Sphingomonadales	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
WH3_k127_7059216_1	1479239.JQMU01000001_gene1962	8.476e-122	392.0	COG5385@1|root,COG5385@2|Bacteria,1MVEY@1224|Proteobacteria,2TSE6@28211|Alphaproteobacteria,2K0H0@204457|Sphingomonadales	204457|Sphingomonadales	S	Histidine phosphotransferase C-terminal domain	-	-	-	ko:K13588	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001	-	-	-	HPTransfase
WH3_k127_7059216_4	1248917.ANFX01000007_gene17	1.336e-16	79.0	COG1310@1|root,COG1310@2|Bacteria,1NC23@1224|Proteobacteria,2UGM4@28211|Alphaproteobacteria,2K62I@204457|Sphingomonadales	204457|Sphingomonadales	L	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
WH3_k127_7076197_1	1248917.ANFX01000037_gene2171	3.289e-267	825.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,2K1MA@204457|Sphingomonadales	204457|Sphingomonadales	O	cytochrome C	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WH3_k127_7076197_5	1479239.JQMU01000001_gene465	8.528e-100	328.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,2K4IY@204457|Sphingomonadales	204457|Sphingomonadales	CO	Alkyl hydroperoxide reductase	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
WH3_k127_7076197_7	1122970.AUHC01000009_gene263	4.637e-68	233.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2U96P@28211|Alphaproteobacteria,2K57D@204457|Sphingomonadales	204457|Sphingomonadales	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
WH3_k127_7076197_4	1479239.JQMU01000001_gene463	1.502e-114	374.0	COG4235@1|root,COG4235@2|Bacteria,1RB0I@1224|Proteobacteria,2U69S@28211|Alphaproteobacteria,2K4DU@204457|Sphingomonadales	204457|Sphingomonadales	O	Cytochrome c biogenesis factor	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_14,TPR_16,TPR_19
WH3_k127_7076197_0	1122970.AUHC01000009_gene261	0.0	1069.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2TRVJ@28211|Alphaproteobacteria,2JZUZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
WH3_k127_7076197_3	1479239.JQMU01000001_gene461	1.45e-122	399.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2U74X@28211|Alphaproteobacteria,2K4N8@204457|Sphingomonadales	204457|Sphingomonadales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
WH3_k127_7076197_2	1248917.ANFX01000037_gene2177	1.374e-182	574.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,2K03J@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WH3_k127_7076197_6	1479239.JQMU01000001_gene459	3.157e-78	264.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,2K0WZ@204457|Sphingomonadales	204457|Sphingomonadales	J	2-methylthioadenine	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
WH3_k127_7076496_0	1479239.JQMU01000001_gene1407	1.192e-163	520.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,2JZXM@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
WH3_k127_7076496_6	1479239.JQMU01000001_gene1408	9.832e-42	158.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2UBS3@28211|Alphaproteobacteria,2K6HZ@204457|Sphingomonadales	204457|Sphingomonadales	J	S4 RNA-binding domain	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
WH3_k127_7076496_4	1479239.JQMU01000001_gene1409	4.995e-70	237.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,2K4E8@204457|Sphingomonadales	204457|Sphingomonadales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
WH3_k127_7076496_2	1248917.ANFX01000005_gene116	2.747e-104	340.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria,2K0TA@204457|Sphingomonadales	204457|Sphingomonadales	K	CarD family transcriptional regulator	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
WH3_k127_7076496_3	1248917.ANFX01000005_gene117	3.733e-100	339.0	COG3595@1|root,COG3595@2|Bacteria,1N374@1224|Proteobacteria,2UDAB@28211|Alphaproteobacteria,2K1A2@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
WH3_k127_7076496_5	1479239.JQMU01000001_gene1412	6.031e-43	159.0	2DCTG@1|root,2ZF9T@2|Bacteria,1N82Z@1224|Proteobacteria,2UGXI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7076496_1	1248917.ANFX01000005_gene119	9.398e-141	452.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,2K1JS@204457|Sphingomonadales	204457|Sphingomonadales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WH3_k127_7099565_2	1479239.JQMU01000001_gene2790	1.076e-105	347.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,2K1RP@204457|Sphingomonadales	204457|Sphingomonadales	H	molybdopterin biosynthesis	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WH3_k127_7099565_1	1479239.JQMU01000001_gene2791	4.952e-128	411.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,2K1AX@204457|Sphingomonadales	204457|Sphingomonadales	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WH3_k127_7099565_0	1479239.JQMU01000001_gene2792	4.799e-168	533.0	COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,2K0XJ@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane metal-binding protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
WH3_k127_7110948_2	1479239.JQMU01000001_gene1432	9.353e-99	327.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2U9H5@28211|Alphaproteobacteria,2K2S3@204457|Sphingomonadales	204457|Sphingomonadales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WH3_k127_7110948_0	1479239.JQMU01000001_gene1431	2.682e-169	538.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2TT66@28211|Alphaproteobacteria,2K0GA@204457|Sphingomonadales	204457|Sphingomonadales	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
WH3_k127_7110948_1	1248917.ANFX01000005_gene137	2.502e-106	346.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria,2JZZP@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WH3_k127_7112835_3	1479239.JQMU01000001_gene524	1.798e-32	126.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1MX4I@1224|Proteobacteria,2TVMQ@28211|Alphaproteobacteria,2K105@204457|Sphingomonadales	204457|Sphingomonadales	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
WH3_k127_7112835_0	1248917.ANFX01000027_gene1071	4.801e-266	821.0	COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria,2K05F@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH3_k127_7112835_2	1479239.JQMU01000001_gene256	2.288e-69	236.0	COG2204@1|root,COG2204@2|Bacteria,1RD1D@1224|Proteobacteria,2U76U@28211|Alphaproteobacteria,2KE99@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	ko:K13589	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WH3_k127_7112835_1	1479239.JQMU01000001_gene255	3.464e-79	269.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,2K41R@204457|Sphingomonadales	204457|Sphingomonadales	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
WH3_k127_7134556_8	1479239.JQMU01000001_gene2854	6.399e-68	232.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TRP2@28211|Alphaproteobacteria,2K0DK@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WH3_k127_7134556_2	1479239.JQMU01000001_gene2853	9.468e-226	710.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TUK2@28211|Alphaproteobacteria,2K0RW@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WH3_k127_7134556_7	1479239.JQMU01000001_gene2852	1.025e-117	382.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2U835@28211|Alphaproteobacteria,2K15P@204457|Sphingomonadales	204457|Sphingomonadales	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
WH3_k127_7134556_1	1479239.JQMU01000001_gene2851	6.135e-263	817.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2U1E2@28211|Alphaproteobacteria,2K08I@204457|Sphingomonadales	204457|Sphingomonadales	M	Chain-length determining protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
WH3_k127_7134556_6	1479239.JQMU01000001_gene2850	1.68e-141	456.0	COG0489@1|root,COG0489@2|Bacteria,1PDUC@1224|Proteobacteria,2U2MQ@28211|Alphaproteobacteria,2K065@204457|Sphingomonadales	204457|Sphingomonadales	D	involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA
WH3_k127_7134556_0	1479239.JQMU01000001_gene2849	5.665e-291	904.0	COG5338@1|root,COG5338@2|Bacteria,1R7QB@1224|Proteobacteria,2TSCP@28211|Alphaproteobacteria,2K2HY@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7134556_3	1479239.JQMU01000001_gene2848	7.947e-210	656.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2U1EJ@28211|Alphaproteobacteria,2K06V@204457|Sphingomonadales	204457|Sphingomonadales	U	Type II secretory pathway, component ExeA	exeA	-	-	-	-	-	-	-	-	-	-	-	AAA_22
WH3_k127_7134556_5	1479239.JQMU01000001_gene2847	6.055e-176	554.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TVFK@28211|Alphaproteobacteria,2JZZ5@204457|Sphingomonadales	204457|Sphingomonadales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
WH3_k127_7134556_4	1479239.JQMU01000001_gene2846	5.217e-186	593.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2TTYM@28211|Alphaproteobacteria,2K1U6@204457|Sphingomonadales	204457|Sphingomonadales	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WH3_k127_7186373_1	1044.EH31_01665	8.738e-19	85.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2K2A3@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH3_k127_7186373_0	1479239.JQMU01000001_gene2682	4.03e-197	625.0	COG0624@1|root,COG0624@2|Bacteria,1NYRF@1224|Proteobacteria,2U0BV@28211|Alphaproteobacteria,2K1FY@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WH3_k127_7186373_2	1479239.JQMU01000001_gene2683	6.554e-17	81.0	2AMAU@1|root,31C5X@2|Bacteria,1NMZT@1224|Proteobacteria,2UN1A@28211|Alphaproteobacteria,2K7FA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7193622_3	1248917.ANFX01000014_gene1346	2.361e-75	258.0	COG1376@1|root,COG1376@2|Bacteria,1RKB2@1224|Proteobacteria,2UAA8@28211|Alphaproteobacteria,2K4DR@204457|Sphingomonadales	204457|Sphingomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	TAT_signal,YkuD_2
WH3_k127_7193622_0	1479239.JQMU01000001_gene970	1.214e-232	731.0	COG2072@1|root,COG2072@2|Bacteria,1QADR@1224|Proteobacteria,2U660@28211|Alphaproteobacteria,2K8RP@204457|Sphingomonadales	204457|Sphingomonadales	P	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
WH3_k127_7193622_1	1479239.JQMU01000001_gene969	1.817e-178	561.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRGU@28211|Alphaproteobacteria,2K07K@204457|Sphingomonadales	204457|Sphingomonadales	BQ	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WH3_k127_7193622_2	383381.EH30_11270	1.124e-75	256.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,2U6TQ@28211|Alphaproteobacteria,2K7JR@204457|Sphingomonadales	204457|Sphingomonadales	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
WH3_k127_7221199_0	1479239.JQMU01000001_gene477	5.763e-179	565.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,2K0AZ@204457|Sphingomonadales	204457|Sphingomonadales	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
WH3_k127_7221199_1	1248917.ANFX01000037_gene2162	1.651e-126	409.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,2K0GI@204457|Sphingomonadales	204457|Sphingomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WH3_k127_7225707_1	1122970.AUHC01000002_gene1429	2.798e-104	339.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2TR6C@28211|Alphaproteobacteria,2K0IW@204457|Sphingomonadales	204457|Sphingomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WH3_k127_7225707_0	1479239.JQMU01000001_gene901	9.462e-316	969.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,2K1GP@204457|Sphingomonadales	204457|Sphingomonadales	E	Glycine dehydrogenase (aminomethyl-transferring)	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
WH3_k127_723959_0	1248917.ANFX01000013_gene1576	0.0	1154.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,2K14B@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WH3_k127_7241825_2	1248917.ANFX01000005_gene103	3.96e-51	182.0	COG3812@1|root,COG3812@2|Bacteria,1RCDT@1224|Proteobacteria,2U6UR@28211|Alphaproteobacteria,2K6G3@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1993)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1993
WH3_k127_7241825_1	1479239.JQMU01000001_gene1403	5.07e-102	335.0	COG3619@1|root,COG3619@2|Bacteria,1N3T5@1224|Proteobacteria,2U3H0@28211|Alphaproteobacteria,2K5F9@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
WH3_k127_7241825_3	1248917.ANFX01000005_gene105	1.273e-26	114.0	COG1872@1|root,COG1872@2|Bacteria,1NGWG@1224|Proteobacteria,2VEEC@28211|Alphaproteobacteria,2K7Q4@204457|Sphingomonadales	204457|Sphingomonadales	S	DUF167	-	-	-	-	-	-	-	-	-	-	-	-	DUF167
WH3_k127_7241825_0	1044.EH31_12620	6.08e-105	343.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,2K4AW@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WH3_k127_7241825_4	383381.EH30_15180	1.693e-21	93.0	COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2U97G@28211|Alphaproteobacteria,2K59G@204457|Sphingomonadales	204457|Sphingomonadales	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WH3_k127_725567_2	366602.Caul_1288	8.172e-28	113.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2KFW6@204458|Caulobacterales	204458|Caulobacterales	EG	Dehydratase family	-	-	-	ko:K22216	-	-	-	-	ko00000	-	-	-	ILVD_EDD
WH3_k127_725567_1	1122970.AUHC01000005_gene1999	4.216e-71	250.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,2K68P@204457|Sphingomonadales	204457|Sphingomonadales	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
WH3_k127_725567_0	1248917.ANFX01000022_gene690	7.971e-200	634.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,2K185@204457|Sphingomonadales	204457|Sphingomonadales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
WH3_k127_7274881_0	1079460.ATTQ01000006_gene3334	2.791e-101	356.0	COG0457@1|root,COG1629@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,COG4771@2|Bacteria,1RJUD@1224|Proteobacteria,2U2AY@28211|Alphaproteobacteria,4BA1D@82115|Rhizobiaceae	28211|Alphaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
WH3_k127_7288796_2	1479239.JQMU01000001_gene178	5.834e-38	143.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,PilZ
WH3_k127_7288796_0	1479239.JQMU01000001_gene177	0.0	1254.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VD4Q@28211|Alphaproteobacteria,2K9BX@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WH3_k127_7288796_1	1479239.JQMU01000001_gene176	2.76e-219	683.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,2K17X@204457|Sphingomonadales	204457|Sphingomonadales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WH3_k127_7292269_2	1122970.AUHC01000008_gene89	5.233e-28	115.0	2BMMB@1|root,3149M@2|Bacteria,1N9JR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7292269_1	1479239.JQMU01000001_gene709	2.936e-57	204.0	29P04@1|root,309Y9@2|Bacteria,1NK7D@1224|Proteobacteria,2UNIE@28211|Alphaproteobacteria,2K6YM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7292269_0	383381.EH30_08510	1.853e-200	625.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TTJP@28211|Alphaproteobacteria,2K07M@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
WH3_k127_7340247_2	685035.ADAE01000018_gene821	4.511e-69	235.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,2K0TB@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
WH3_k127_7340247_3	1248917.ANFX01000037_gene2084	3.694e-55	203.0	2CIZA@1|root,32S8U@2|Bacteria,1N29D@1224|Proteobacteria,2UEH4@28211|Alphaproteobacteria,2KATK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7340247_0	1479239.JQMU01000001_gene2519	1.377e-180	567.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,2K0XU@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WH3_k127_7340247_1	1479239.JQMU01000001_gene2520	2.778e-92	304.0	COG2135@1|root,COG2135@2|Bacteria,1RABZ@1224|Proteobacteria,2U6AM@28211|Alphaproteobacteria,2K4CE@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
WH3_k127_737210_3	1479239.JQMU01000001_gene140	2.284e-90	302.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,2K03V@204457|Sphingomonadales	204457|Sphingomonadales	M	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WH3_k127_737210_0	1479239.JQMU01000001_gene141	9.528e-307	943.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2TR8V@28211|Alphaproteobacteria,2K0C0@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
WH3_k127_737210_2	1479239.JQMU01000001_gene142	2.729e-124	400.0	COG0300@1|root,COG0300@2|Bacteria,1QUNR@1224|Proteobacteria,2TW24@28211|Alphaproteobacteria,2K1AC@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH3_k127_737210_4	1479239.JQMU01000001_gene143	8.333e-70	236.0	28YKP@1|root,2ZKEE@2|Bacteria,1NBD7@1224|Proteobacteria,2UHHD@28211|Alphaproteobacteria,2K531@204457|Sphingomonadales	204457|Sphingomonadales	S	Pilus assembly protein PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WH3_k127_737210_1	1248917.ANFX01000030_gene555	3.81e-200	626.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,2TTI5@28211|Alphaproteobacteria,2K1R1@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WH3_k127_7424661_1	1479239.JQMU01000001_gene961	3.306e-77	262.0	COG0454@1|root,COG0456@2|Bacteria,1RI7M@1224|Proteobacteria,2UAKW@28211|Alphaproteobacteria,2K51C@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WH3_k127_7424661_0	1248917.ANFX01000014_gene1360	1.671e-181	573.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,2TU8K@28211|Alphaproteobacteria,2K0JU@204457|Sphingomonadales	204457|Sphingomonadales	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
WH3_k127_7432586_2	1479239.JQMU01000001_gene1393	1.7e-183	579.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K001@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WH3_k127_7432586_3	1248917.ANFX01000005_gene92	1.008e-140	449.0	COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria,2K0D3@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09987	-	-	-	-	ko00000	-	-	-	DUF1013
WH3_k127_7432586_0	1479239.JQMU01000001_gene1395	7.011e-217	676.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria,2K08Y@204457|Sphingomonadales	204457|Sphingomonadales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
WH3_k127_7432586_1	1479239.JQMU01000001_gene1396	1.521e-191	602.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2TSEB@28211|Alphaproteobacteria,2K0Q8@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
WH3_k127_7432586_4	1122970.AUHC01000010_gene1590	6.642e-108	353.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,2K0R9@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
WH3_k127_7432586_5	1044.EH31_12660	2.812e-63	218.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,2K115@204457|Sphingomonadales	204457|Sphingomonadales	C	NADPH quinone	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
WH3_k127_7495148_3	1248917.ANFX01000016_gene2466	2.333e-218	682.0	COG2204@1|root,COG2204@2|Bacteria,1P98K@1224|Proteobacteria,2TUM0@28211|Alphaproteobacteria,2K3AF@204457|Sphingomonadales	204457|Sphingomonadales	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_8
WH3_k127_7495148_4	1479239.JQMU01000001_gene2020	1.799e-154	491.0	COG5012@1|root,COG5012@2|Bacteria,1RJN6@1224|Proteobacteria,2U9SK@28211|Alphaproteobacteria,2K2S6@204457|Sphingomonadales	204457|Sphingomonadales	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
WH3_k127_7495148_6	1479239.JQMU01000001_gene2019	2.711e-92	305.0	294R4@1|root,2ZS4D@2|Bacteria,1RDGM@1224|Proteobacteria,2U71V@28211|Alphaproteobacteria,2K4C2@204457|Sphingomonadales	204457|Sphingomonadales	S	2-vinyl bacteriochlorophyllide hydratase (BCHF)	-	-	4.2.1.165	ko:K11336	ko00860,ko01110,map00860,map01110	-	R09054,R09059	RC02412	ko00000,ko00001,ko01000	-	-	-	BCHF
WH3_k127_7495148_2	1479239.JQMU01000001_gene2018	6.684e-262	817.0	COG2710@1|root,COG2710@2|Bacteria,1MVP0@1224|Proteobacteria,2TSK1@28211|Alphaproteobacteria,2K0EI@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex	bchN	-	1.3.7.7	ko:K04038	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro
WH3_k127_7495148_1	1248917.ANFX01000016_gene2470	5.244e-315	967.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,2TSTQ@28211|Alphaproteobacteria,2K1A9@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex	bchB	-	1.3.7.7	ko:K04039	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
WH3_k127_7495148_0	1479239.JQMU01000001_gene2016	0.0	2183.0	COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2TQVD@28211|Alphaproteobacteria,2K02Q@204457|Sphingomonadales	204457|Sphingomonadales	H	CobN/Magnesium Chelatase	bchH	-	6.6.1.1,6.6.1.2	ko:K02230,ko:K03403	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877,R05227	RC01012,RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,DUF3479
WH3_k127_7495148_5	1479239.JQMU01000001_gene2015	8.415e-146	463.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria,2K1YK@204457|Sphingomonadales	204457|Sphingomonadales	D	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP	nifH	-	1.18.6.1,1.3.7.7	ko:K02588,ko:K04037	ko00625,ko00860,ko00910,ko01100,ko01110,ko01120,map00625,map00860,map00910,map01100,map01110,map01120	M00175	R05185,R05496,R06282	RC00002,RC01008,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
WH3_k127_7495771_10	1479239.JQMU01000001_gene666	9.972e-18	82.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,2K0TI@204457|Sphingomonadales	204457|Sphingomonadales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
WH3_k127_7495771_7	1479239.JQMU01000001_gene665	1.182e-188	593.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria,2K0WW@204457|Sphingomonadales	204457|Sphingomonadales	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
WH3_k127_7495771_9	1479239.JQMU01000001_gene664	7.054e-141	454.0	COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria,2U3PZ@28211|Alphaproteobacteria,2K1KZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
WH3_k127_7495771_2	1479239.JQMU01000001_gene663	2.771e-308	948.0	COG0644@1|root,COG0644@2|Bacteria,1R41S@1224|Proteobacteria,2TW03@28211|Alphaproteobacteria,2KE9W@204457|Sphingomonadales	204457|Sphingomonadales	C	Tryptophan halogenase	-	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
WH3_k127_7495771_0	1248917.ANFX01000032_gene839	0.0	1816.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MV8W@1224|Proteobacteria,2TSUV@28211|Alphaproteobacteria,2JZV0@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
WH3_k127_7495771_8	1479239.JQMU01000001_gene661	6.377e-181	570.0	COG2273@1|root,COG2273@2|Bacteria,1NFHX@1224|Proteobacteria,2TU8E@28211|Alphaproteobacteria,2KCYM@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
WH3_k127_7495771_6	1479239.JQMU01000001_gene660	3.796e-195	617.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2VG10@28211|Alphaproteobacteria,2KCZ2@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
WH3_k127_7495771_5	1479239.JQMU01000001_gene659	6.672e-196	618.0	COG0477@1|root,COG2814@2|Bacteria,1QXKT@1224|Proteobacteria,2TXC1@28211|Alphaproteobacteria,2KEHN@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_7495771_1	1479239.JQMU01000001_gene658	0.0	1265.0	COG1472@1|root,COG1472@2|Bacteria,1MVIV@1224|Proteobacteria,2UPID@28211|Alphaproteobacteria,2KD3B@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
WH3_k127_7495771_4	1479239.JQMU01000001_gene655	3.163e-197	620.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2TSFB@28211|Alphaproteobacteria,2K29T@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
WH3_k127_7495771_3	1479239.JQMU01000001_gene654	1.75e-254	791.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2TSY7@28211|Alphaproteobacteria,2K0D9@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
WH3_k127_7500332_2	1479239.JQMU01000001_gene792	2.097e-69	235.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,2K0U5@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S10 serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
WH3_k127_7500332_1	1479239.JQMU01000001_gene793	2.198e-70	244.0	2A23D@1|root,30QDK@2|Bacteria,1P5FW@1224|Proteobacteria,2UXQF@28211|Alphaproteobacteria,2K79W@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7500332_0	1479239.JQMU01000001_gene794	1.301e-209	655.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,2K11D@204457|Sphingomonadales	204457|Sphingomonadales	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbC,DsbD,Thioredoxin_7
WH3_k127_7539827_5	1248917.ANFX01000016_gene2476	1.683e-21	95.0	COG3428@1|root,COG3428@2|Bacteria,1RHA4@1224|Proteobacteria,2UA6D@28211|Alphaproteobacteria,2K1SW@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
WH3_k127_7539827_3	1479239.JQMU01000001_gene2010	2.458e-76	258.0	2E3IS@1|root,32YH7@2|Bacteria,1N9I5@1224|Proteobacteria,2UGHF@28211|Alphaproteobacteria,2K6HN@204457|Sphingomonadales	204457|Sphingomonadales	S	Photosynthetic complex assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7539827_4	1248917.ANFX01000016_gene2478	3.593e-46	169.0	2E7QH@1|root,3325Y@2|Bacteria,1MZ3C@1224|Proteobacteria,2UG5F@28211|Alphaproteobacteria,2K66G@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7539827_0	1248917.ANFX01000016_gene2479	1.192e-211	666.0	COG1633@1|root,COG1633@2|Bacteria,1N5FH@1224|Proteobacteria,2TU0E@28211|Alphaproteobacteria,2K1MB@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	acsF	-	1.14.13.81	ko:K04035	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06265,R06266,R06267,R10068	RC00741,RC01491,RC01492,RC03042	ko00000,ko00001,ko01000	-	-	-	Rubrerythrin
WH3_k127_7539827_2	1479239.JQMU01000001_gene2007	4.291e-135	437.0	COG0523@1|root,COG0523@2|Bacteria,1MY4T@1224|Proteobacteria,2U0DU@28211|Alphaproteobacteria,2K41B@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3623)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3623
WH3_k127_7539827_1	1479239.JQMU01000001_gene2006	1.542e-176	555.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,2K08Q@204457|Sphingomonadales	204457|Sphingomonadales	E	5-aminolevulinic acid synthase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WH3_k127_7548690_2	1479239.JQMU01000001_gene2201	1.352e-48	175.0	COG3391@1|root,COG3391@2|Bacteria,1MXXH@1224|Proteobacteria,2TW31@28211|Alphaproteobacteria,2K2PG@204457|Sphingomonadales	204457|Sphingomonadales	S	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
WH3_k127_7548690_1	1479239.JQMU01000001_gene2200	1.758e-123	399.0	2ENSP@1|root,33GDV@2|Bacteria,1N3J8@1224|Proteobacteria,2UBZE@28211|Alphaproteobacteria,2K5KK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7548690_0	1479239.JQMU01000001_gene2199	3.666e-285	880.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,2K1MH@204457|Sphingomonadales	204457|Sphingomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WH3_k127_7601093_0	1248917.ANFX01000011_gene191	1.253e-158	510.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,2K09B@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WH3_k127_7601093_1	1479239.JQMU01000001_gene533	3.155e-105	347.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,2K0PK@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
WH3_k127_7605814_1	1122970.AUHC01000001_gene714	1.231e-71	253.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales	204457|Sphingomonadales	V	Secretion protein, HlyD	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WH3_k127_7605814_2	1248917.ANFX01000030_gene486	2.1e-69	238.0	COG1846@1|root,COG1846@2|Bacteria,1MZY5@1224|Proteobacteria,2U9EE@28211|Alphaproteobacteria,2K62J@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WH3_k127_7605814_0	1479239.JQMU01000001_gene205	3.087e-122	394.0	COG3917@1|root,COG3917@2|Bacteria,1MV6E@1224|Proteobacteria,2TVJ4@28211|Alphaproteobacteria,2K0YH@204457|Sphingomonadales	204457|Sphingomonadales	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
WH3_k127_7605814_3	1479239.JQMU01000001_gene204	1.594e-16	84.0	COG2267@1|root,COG2267@2|Bacteria,1QUNU@1224|Proteobacteria,2TW29@28211|Alphaproteobacteria,2K09G@204457|Sphingomonadales	204457|Sphingomonadales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WH3_k127_7629312_0	1479239.JQMU01000001_gene2012	1.827e-156	495.0	COG3861@1|root,COG3861@2|Bacteria,1NU42@1224|Proteobacteria,2TTV5@28211|Alphaproteobacteria,2K0VQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Photosynthetic reaction centre, H-chain N-terminal region	-	-	-	ko:K13991	ko02020,map02020	-	-	-	ko00000,ko00001,ko00194	-	-	-	PRC,PRCH
WH3_k127_7629312_1	1479239.JQMU01000001_gene2011	8.394e-115	374.0	COG3428@1|root,COG3428@2|Bacteria,1RHA4@1224|Proteobacteria,2UA6D@28211|Alphaproteobacteria,2K1SW@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
WH3_k127_7629312_2	1479239.JQMU01000001_gene2010	4.463e-57	200.0	2E3IS@1|root,32YH7@2|Bacteria,1N9I5@1224|Proteobacteria,2UGHF@28211|Alphaproteobacteria,2K6HN@204457|Sphingomonadales	204457|Sphingomonadales	S	Photosynthetic complex assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7630522_0	1479239.JQMU01000001_gene2214	4e-208	652.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2K0EB@204457|Sphingomonadales	204457|Sphingomonadales	P	P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WH3_k127_7630522_1	1248917.ANFX01000012_gene1806	1.386e-60	211.0	COG5456@1|root,COG5456@2|Bacteria,1RHKI@1224|Proteobacteria,2U9GB@28211|Alphaproteobacteria,2K623@204457|Sphingomonadales	204457|Sphingomonadales	P	Integral membrane protein linked to a cation	-	-	-	-	-	-	-	-	-	-	-	-	FixH
WH3_k127_763464_0	1479239.JQMU01000001_gene178	4.178e-227	716.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,PilZ
WH3_k127_763464_1	1479239.JQMU01000001_gene179	1.538e-208	652.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TVC3@28211|Alphaproteobacteria,2K3AC@204457|Sphingomonadales	204457|Sphingomonadales	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
WH3_k127_7703732_2	314225.ELI_02265	1.165e-81	285.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2K0QG@204457|Sphingomonadales	204457|Sphingomonadales	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WH3_k127_7703732_0	1479239.JQMU01000001_gene2408	1.66e-105	350.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,2K1EB@204457|Sphingomonadales	204457|Sphingomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WH3_k127_7703732_1	1248917.ANFX01000038_gene581	7.451e-102	332.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2K0RE@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K13581	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko02048	-	-	-	N6_N4_Mtase
WH3_k127_7781581_3	383381.EH30_13505	6.824e-34	132.0	COG3326@1|root,COG3326@2|Bacteria,1NGR5@1224|Proteobacteria,2UJDY@28211|Alphaproteobacteria,2KBEU@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
WH3_k127_7781581_0	1479239.JQMU01000001_gene1115	6.432e-223	692.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2TS3X@28211|Alphaproteobacteria,2K1H7@204457|Sphingomonadales	204457|Sphingomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
WH3_k127_7781581_1	1248917.ANFX01000006_gene86	5.191e-57	198.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2K0F8@204457|Sphingomonadales	204457|Sphingomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
WH3_k127_786094_6	1479239.JQMU01000001_gene707	2.157e-72	244.0	COG2932@1|root,COG2932@2|Bacteria,1N97M@1224|Proteobacteria,2UF88@28211|Alphaproteobacteria,2K4JZ@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
WH3_k127_786094_3	1479239.JQMU01000001_gene706	1.7e-151	481.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2TQJ9@28211|Alphaproteobacteria,2K19S@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH3_k127_786094_8	1479239.JQMU01000001_gene705	6.407e-60	212.0	COG3788@1|root,COG3788@2|Bacteria,1N0G5@1224|Proteobacteria,2UDEJ@28211|Alphaproteobacteria,2K642@204457|Sphingomonadales	204457|Sphingomonadales	S	relative of glutathione S-transferase, MAPEG superfamily	-	-	-	ko:K07136	-	-	-	-	ko00000	-	-	-	MAPEG
WH3_k127_786094_11	1207055.C100_17785	6.692e-29	115.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,2K6RY@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WH3_k127_786094_1	1479239.JQMU01000001_gene703	2.852e-201	631.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2TR53@28211|Alphaproteobacteria,2K0QU@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WH3_k127_786094_2	1479239.JQMU01000001_gene702	5.883e-184	578.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,2K1XQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WH3_k127_786094_9	1479239.JQMU01000001_gene701	4.581e-54	191.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2UCDG@28211|Alphaproteobacteria,2K62D@204457|Sphingomonadales	204457|Sphingomonadales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WH3_k127_786094_7	1479239.JQMU01000001_gene700	1.346e-66	229.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2U9A5@28211|Alphaproteobacteria,2K5Y3@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
WH3_k127_786094_0	1479239.JQMU01000001_gene699	0.0	1778.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,2K02F@204457|Sphingomonadales	204457|Sphingomonadales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
WH3_k127_786094_5	1479239.JQMU01000001_gene698	8.311e-103	340.0	COG1651@1|root,COG1651@2|Bacteria,1RBWK@1224|Proteobacteria,2U6HJ@28211|Alphaproteobacteria,2K3W7@204457|Sphingomonadales	204457|Sphingomonadales	M	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WH3_k127_786094_4	1479239.JQMU01000001_gene697	7.067e-110	360.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,2K57Q@204457|Sphingomonadales	204457|Sphingomonadales	M	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WH3_k127_786094_12	717785.HYPMC_4593	2.477e-16	81.0	COG2240@1|root,COG2240@2|Bacteria,1MVC9@1224|Proteobacteria,2U2CH@28211|Alphaproteobacteria,3N8R7@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	H	Belongs to the pyridoxine kinase family	pdxK	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
WH3_k127_7954409_1	1122970.AUHC01000013_gene1031	5.954e-14	71.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria,2K14X@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WH3_k127_7954409_0	1248917.ANFX01000014_gene1325	4.388e-132	449.0	COG0790@1|root,COG5640@1|root,COG0790@2|Bacteria,COG5640@2|Bacteria,1PEP7@1224|Proteobacteria,2VE7G@28211|Alphaproteobacteria,2K9SA@204457|Sphingomonadales	204457|Sphingomonadales	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
WH3_k127_7973988_1	1479239.JQMU01000001_gene2391	3.13e-99	326.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0TH@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WH3_k127_7973988_4	1479239.JQMU01000001_gene2393	4.437e-28	115.0	2BPTS@1|root,32IM6@2|Bacteria,1NJGE@1224|Proteobacteria,2UM6C@28211|Alphaproteobacteria,2K83I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_7973988_2	1479239.JQMU01000001_gene2394	4.102e-95	318.0	COG0810@1|root,COG0810@2|Bacteria,1RCAG@1224|Proteobacteria,2U664@28211|Alphaproteobacteria,2K6J3@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0810 Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WH3_k127_7973988_0	1479239.JQMU01000001_gene2395	8.987e-141	452.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria,2JZVR@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha Beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
WH3_k127_7973988_3	1044.EH31_07780	8.486e-57	203.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2JZZX@204457|Sphingomonadales	204457|Sphingomonadales	E	overlaps another CDS with the same product name	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WH3_k127_8018980_0	1479239.JQMU01000001_gene1059	5.405e-183	576.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,2JZXY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WH3_k127_8018980_1	1479239.JQMU01000001_gene1060	1.086e-168	536.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,2K18X@204457|Sphingomonadales	204457|Sphingomonadales	E	Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate	tyrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00220	ko00400,ko00401,ko01100,ko01110,ko01230,map00400,map00401,map01100,map01110,map01230	M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
WH3_k127_8018980_2	1479239.JQMU01000001_gene1068	4.131e-103	337.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,2K3XJ@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WH3_k127_8023785_1	1479239.JQMU01000001_gene1021	3.463e-303	933.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,2K0HU@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2
WH3_k127_8023785_6	1479239.JQMU01000001_gene1020	7.161e-86	289.0	COG2137@1|root,COG2137@2|Bacteria,1N2EE@1224|Proteobacteria,2U96W@28211|Alphaproteobacteria,2K59F@204457|Sphingomonadales	204457|Sphingomonadales	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WH3_k127_8023785_9	1122970.AUHC01000002_gene1414	3.418e-67	233.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,2K5JY@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
WH3_k127_8023785_7	1479239.JQMU01000001_gene1017	6.105e-83	276.0	COG3761@1|root,COG3761@2|Bacteria,1RHS3@1224|Proteobacteria,2U95G@28211|Alphaproteobacteria,2K5FH@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH ubiquinone oxidoreductase 17.2 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	NDUFA12
WH3_k127_8023785_4	1479239.JQMU01000001_gene1015	2.658e-121	398.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2U59K@28211|Alphaproteobacteria,2K180@204457|Sphingomonadales	204457|Sphingomonadales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
WH3_k127_8023785_14	661478.OP10G_0131	6.02e-09	57.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WH3_k127_8023785_0	1096930.L284_06235	0.0	1032.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2TRVM@28211|Alphaproteobacteria,2K051@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
WH3_k127_8023785_10	1479239.JQMU01000001_gene1013	2.62e-31	124.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria,2K6WV@204457|Sphingomonadales	204457|Sphingomonadales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
WH3_k127_8023785_5	1479239.JQMU01000001_gene1012	1.618e-107	351.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2TRID@28211|Alphaproteobacteria,2K0IB@204457|Sphingomonadales	204457|Sphingomonadales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
WH3_k127_8023785_12	1479239.JQMU01000001_gene1011	6.318e-19	90.0	2BBFK@1|root,324YV@2|Bacteria,1NF3M@1224|Proteobacteria,2UIN4@28211|Alphaproteobacteria,2K7VH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8023785_8	1479239.JQMU01000001_gene1010	1.742e-78	263.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2U760@28211|Alphaproteobacteria,2K3Z9@204457|Sphingomonadales	204457|Sphingomonadales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
WH3_k127_8023785_3	1248917.ANFX01000014_gene1304	1.721e-128	413.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2TRXP@28211|Alphaproteobacteria,2K0YM@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WH3_k127_8023785_2	1122970.AUHC01000023_gene2511	1.407e-145	463.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2K05Q@204457|Sphingomonadales	204457|Sphingomonadales	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
WH3_k127_8026627_1	1479239.JQMU01000001_gene1323	5.294e-89	296.0	COG2207@1|root,COG2207@2|Bacteria,1RAXU@1224|Proteobacteria,2U682@28211|Alphaproteobacteria,2K33E@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WH3_k127_8026627_0	1248917.ANFX01000021_gene1645	1.777e-163	521.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,2K0XB@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WH3_k127_8030640_1	935557.ATYB01000008_gene5792	1.23e-90	307.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2U6VS@28211|Alphaproteobacteria,4BM30@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	cyaK	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WH3_k127_8030640_3	517722.AEUE01000008_gene86	5.746e-49	185.0	COG1595@1|root,COG1595@2|Bacteria,1RJ86@1224|Proteobacteria,2UAQC@28211|Alphaproteobacteria,2K5QJ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_8030640_2	685035.ADAE01000003_gene2846	3.024e-72	255.0	COG3712@1|root,COG3712@2|Bacteria,1RJVJ@1224|Proteobacteria,2U9Q3@28211|Alphaproteobacteria,2K4P9@204457|Sphingomonadales	204457|Sphingomonadales	PT	Fe2 -dicitrate sensor, membrane component	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
WH3_k127_8030640_0	1088721.NSU_3584	7.108e-151	489.0	COG1629@1|root,COG4771@2|Bacteria,1MXD7@1224|Proteobacteria,2U07R@28211|Alphaproteobacteria,2KECN@204457|Sphingomonadales	204457|Sphingomonadales	P	Outer membrane receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,STN,TonB_dep_Rec
WH3_k127_8043604_1	383381.EH30_15390	2.594e-35	146.0	COG0810@1|root,COG0810@2|Bacteria,1NDWG@1224|Proteobacteria,2UII0@28211|Alphaproteobacteria,2K7DY@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
WH3_k127_8043604_0	1248917.ANFX01000026_gene1043	6.098e-114	369.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2TR10@28211|Alphaproteobacteria,2K1AU@204457|Sphingomonadales	204457|Sphingomonadales	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WH3_k127_8046152_9	1479239.JQMU01000001_gene1231	1.203e-51	183.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2UJ22@28211|Alphaproteobacteria,2KD76@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the Fur family	-	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
WH3_k127_8046152_6	279238.Saro_2386	1.85e-115	396.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,2K1MH@204457|Sphingomonadales	204457|Sphingomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WH3_k127_8046152_0	1479239.JQMU01000001_gene1232	0.0	1202.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,2K0XY@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
WH3_k127_8046152_4	1479239.JQMU01000001_gene1233	1.844e-142	459.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2U7CZ@28211|Alphaproteobacteria,2K3Q5@204457|Sphingomonadales	204457|Sphingomonadales	M	Lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
WH3_k127_8046152_3	1479239.JQMU01000001_gene1234	8.788e-160	508.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,2TVBC@28211|Alphaproteobacteria,2K0JE@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1,Flavin_Reduct
WH3_k127_8046152_5	1479239.JQMU01000001_gene1235	7.304e-116	376.0	COG4094@1|root,COG4094@2|Bacteria,1RDF9@1224|Proteobacteria,2U7NM@28211|Alphaproteobacteria,2K2CX@204457|Sphingomonadales	204457|Sphingomonadales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
WH3_k127_8046152_8	237727.NAP1_13538	1.86e-66	237.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2U9MH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH3_k127_8046152_10	237727.NAP1_13543	1.545e-51	185.0	COG1733@1|root,COG1733@2|Bacteria,1RKPA@1224|Proteobacteria,2UDWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
WH3_k127_8046152_7	1248917.ANFX01000013_gene1552	2.878e-68	235.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2U8NR@28211|Alphaproteobacteria,2K4UH@204457|Sphingomonadales	204457|Sphingomonadales	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
WH3_k127_8046152_2	1479239.JQMU01000001_gene1236	5.717e-218	683.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2K2YY@204457|Sphingomonadales	204457|Sphingomonadales	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WH3_k127_8046152_1	1248917.ANFX01000013_gene1554	4.649e-267	829.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,2TUMS@28211|Alphaproteobacteria,2K1BD@204457|Sphingomonadales	204457|Sphingomonadales	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WH3_k127_8046152_11	1122970.AUHC01000011_gene2781	4.251e-38	144.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K05X@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
WH3_k127_8050323_3	1248917.ANFX01000030_gene485	1.263e-80	270.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales	204457|Sphingomonadales	V	Secretion protein, HlyD	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WH3_k127_8050323_0	1248917.ANFX01000030_gene484	2.267e-290	898.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,2JZYF@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
WH3_k127_8050323_2	1479239.JQMU01000001_gene206	1.048e-84	286.0	2E0TG@1|root,32WB4@2|Bacteria,1NAQK@1224|Proteobacteria,2UIUC@28211|Alphaproteobacteria,2K7EH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8050323_1	1479239.JQMU01000001_gene208	8.983e-215	668.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,2K104@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WH3_k127_8050323_4	1479239.JQMU01000001_gene209	2.124e-65	226.0	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,2TRVE@28211|Alphaproteobacteria,2K0U1@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
WH3_k127_8050323_5	1121920.AUAU01000018_gene1788	1.339e-48	178.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K03603,ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	DUF4953,DUF5117,FCD,GntR
WH3_k127_8052997_0	1248917.ANFX01000008_gene260	2.278e-129	416.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria,2K03N@204457|Sphingomonadales	204457|Sphingomonadales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
WH3_k127_8052997_1	1479239.JQMU01000001_gene2708	1.424e-103	339.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2U5V2@28211|Alphaproteobacteria,2K3XC@204457|Sphingomonadales	204457|Sphingomonadales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WH3_k127_8052997_2	1081640.AGFU01000067_gene3669	3.748e-15	76.0	COG4253@1|root,COG4253@2|Bacteria,1RJSI@1224|Proteobacteria,2UAVI@28211|Alphaproteobacteria,2K54I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8054499_9	1248917.ANFX01000013_gene1489	1.386e-94	310.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria,2K12J@204457|Sphingomonadales	204457|Sphingomonadales	I	synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
WH3_k127_8054499_7	1248917.ANFX01000013_gene1592	8.067e-95	312.0	2AFT8@1|root,31D88@2|Bacteria,1REHW@1224|Proteobacteria,2U8QX@28211|Alphaproteobacteria,2KDFQ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8054499_3	1479239.JQMU01000001_gene1462	1.152e-188	599.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2K0MM@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
WH3_k127_8054499_13	1479239.JQMU01000001_gene1461	8.269e-55	194.0	2E2R2@1|root,32XTN@2|Bacteria,1NHQU@1224|Proteobacteria,2TVUH@28211|Alphaproteobacteria,2KE8B@204457|Sphingomonadales	204457|Sphingomonadales	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
WH3_k127_8054499_4	383381.EH30_14865	7.204e-175	556.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,2K0QN@204457|Sphingomonadales	204457|Sphingomonadales	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WH3_k127_8054499_16	1248917.ANFX01000013_gene1596	1.41e-38	151.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2UF5Y@28211|Alphaproteobacteria,2K75D@204457|Sphingomonadales	204457|Sphingomonadales	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
WH3_k127_8054499_8	1122970.AUHC01000010_gene1655	1.131e-94	316.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,2K28X@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WH3_k127_8054499_10	1479239.JQMU01000001_gene1457	1.21e-92	306.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria,2K0C7@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WH3_k127_8054499_5	1479239.JQMU01000001_gene1455	4.815e-139	444.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,2U1GX@28211|Alphaproteobacteria,2K28P@204457|Sphingomonadales	204457|Sphingomonadales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WH3_k127_8054499_19	1122970.AUHC01000010_gene1650	1.496e-19	95.0	2BMG2@1|root,32G0S@2|Bacteria,1NIIU@1224|Proteobacteria,2UK8S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8054499_6	1122970.AUHC01000010_gene1649	3.56e-128	416.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2U0M2@28211|Alphaproteobacteria,2K2B0@204457|Sphingomonadales	204457|Sphingomonadales	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
WH3_k127_8054499_2	1479239.JQMU01000001_gene1451	2.558e-223	699.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2UA88@28211|Alphaproteobacteria,2KD4C@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
WH3_k127_8054499_0	1479239.JQMU01000001_gene1450	3.913e-279	861.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,2K0K7@204457|Sphingomonadales	204457|Sphingomonadales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
WH3_k127_8054499_11	1479239.JQMU01000001_gene1449	2.156e-88	296.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2UAEN@28211|Alphaproteobacteria,2KD0C@204457|Sphingomonadales	204457|Sphingomonadales	O	Protein-L-isoaspartate O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WH3_k127_8054499_1	1479239.JQMU01000001_gene1448	1.67e-252	788.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,2JZY5@204457|Sphingomonadales	204457|Sphingomonadales	MU	membrane	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WH3_k127_8054499_12	1479239.JQMU01000001_gene1447	8.443e-67	231.0	COG3827@1|root,COG3827@2|Bacteria,1NH58@1224|Proteobacteria,2VCF9@28211|Alphaproteobacteria,2K6DD@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2497)	-	-	-	ko:K09991	-	-	-	-	ko00000	-	-	-	DUF2497
WH3_k127_8096704_4	1479239.JQMU01000001_gene2130	6.247e-07	53.0	2A1UX@1|root,30Q42@2|Bacteria,1P177@1224|Proteobacteria,2UV7E@28211|Alphaproteobacteria,2K858@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8096704_1	1479239.JQMU01000001_gene2131	2.23e-87	293.0	COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,2K35H@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09985	-	-	-	-	ko00000	-	-	-	SspB
WH3_k127_8096704_0	1479239.JQMU01000001_gene2132	3.154e-119	384.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,2K1TW@204457|Sphingomonadales	204457|Sphingomonadales	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
WH3_k127_8096704_3	702113.PP1Y_AT8522	6.002e-25	109.0	COG2350@1|root,COG2350@2|Bacteria,1N8AZ@1224|Proteobacteria,2UH4F@28211|Alphaproteobacteria,2K6Y1@204457|Sphingomonadales	204457|Sphingomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
WH3_k127_8096704_2	1479239.JQMU01000001_gene2134	3.658e-77	260.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2TTT4@28211|Alphaproteobacteria,2K223@204457|Sphingomonadales	204457|Sphingomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WH3_k127_8102887_0	1248917.ANFX01000022_gene666	0.0	1033.0	COG0365@1|root,COG0604@1|root,COG1024@1|root,COG0365@2|Bacteria,COG0604@2|Bacteria,COG1024@2|Bacteria,1MXIK@1224|Proteobacteria,2U43I@28211|Alphaproteobacteria,2K2UF@204457|Sphingomonadales	204457|Sphingomonadales	CI	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,ECH_1
WH3_k127_8133498_0	1248917.ANFX01000012_gene1760	3.521e-190	597.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2TRMS@28211|Alphaproteobacteria,2K12A@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WH3_k127_8133498_1	1248917.ANFX01000012_gene1759	1.892e-137	439.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2U1U0@28211|Alphaproteobacteria,2K146@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.199	ko:K15922	-	-	R00802,R11543	RC00028,RC00059,RC00077,RC00451	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
WH3_k127_8154627_1	1248917.ANFX01000032_gene1027	3.283e-157	499.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,2K0U5@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S10 serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
WH3_k127_8154627_0	1248917.ANFX01000032_gene978	0.0	1061.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,2K0F9@204457|Sphingomonadales	204457|Sphingomonadales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WH3_k127_8173453_1	1248917.ANFX01000008_gene290	6.071e-149	475.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TWH9@28211|Alphaproteobacteria,2KEEK@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
WH3_k127_8173453_0	1248917.ANFX01000008_gene291	5.939e-182	575.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2K2A3@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WH3_k127_8177923_2	1479239.JQMU01000001_gene1531	3.675e-104	340.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,2K2BW@204457|Sphingomonadales	204457|Sphingomonadales	E	homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
WH3_k127_8177923_1	1479239.JQMU01000001_gene1532	2.263e-126	412.0	2CJQX@1|root,342E0@2|Bacteria,1RA7X@1224|Proteobacteria,2U5C1@28211|Alphaproteobacteria,2KDDU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8177923_3	1479239.JQMU01000001_gene1533	4.937e-101	335.0	COG0810@1|root,COG0810@2|Bacteria,1RCAG@1224|Proteobacteria,2U664@28211|Alphaproteobacteria,2K187@204457|Sphingomonadales	204457|Sphingomonadales	M	Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WH3_k127_8177923_0	1122970.AUHC01000002_gene1301	1.074e-129	418.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2TS4F@28211|Alphaproteobacteria,2K1P2@204457|Sphingomonadales	204457|Sphingomonadales	U	MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
WH3_k127_8177923_4	685035.ADAE01000023_gene1685	1.996e-87	291.0	COG0848@1|root,COG0848@2|Bacteria,1R64K@1224|Proteobacteria,2U4H6@28211|Alphaproteobacteria,2KD52@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WH3_k127_8177923_5	237727.NAP1_12368	2.831e-72	245.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2UEA0@28211|Alphaproteobacteria,2K55Z@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WH3_k127_8177923_6	1248917.ANFX01000019_gene2385	5.82e-55	193.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2K0I6@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
WH3_k127_8179214_2	1248917.ANFX01000047_gene1609	6.534e-20	89.0	COG3182@1|root,COG3182@2|Bacteria,1R59B@1224|Proteobacteria,2U2XT@28211|Alphaproteobacteria,2KCSJ@204457|Sphingomonadales	204457|Sphingomonadales	S	conserved secreted or membrane protein precursor	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
WH3_k127_8179214_0	1479239.JQMU01000001_gene565	1.012e-239	747.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2K2ST@204457|Sphingomonadales	204457|Sphingomonadales	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
WH3_k127_8179214_1	1479239.JQMU01000001_gene564	9.384e-37	139.0	2EB2V@1|root,3353M@2|Bacteria,1QED4@1224|Proteobacteria,2U3RZ@28211|Alphaproteobacteria,2K1M2@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
WH3_k127_8182604_3	1248917.ANFX01000023_gene1234	1.276e-54	193.0	COG0583@1|root,COG0583@2|Bacteria,1MZTA@1224|Proteobacteria,2U1KF@28211|Alphaproteobacteria,2K0U0@204457|Sphingomonadales	204457|Sphingomonadales	K	LysR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WH3_k127_8182604_1	1479239.JQMU01000001_gene623	1.503e-140	449.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2TSR6@28211|Alphaproteobacteria,2K0PN@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
WH3_k127_8182604_2	1248917.ANFX01000023_gene1236	5.558e-97	323.0	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,2U63R@28211|Alphaproteobacteria,2K5T5@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
WH3_k127_8182604_0	1479239.JQMU01000001_gene625	1.942e-223	700.0	COG2271@1|root,COG2271@2|Bacteria,1R2YM@1224|Proteobacteria,2TZX8@28211|Alphaproteobacteria,2KBQH@204457|Sphingomonadales	1224|Proteobacteria	G	Acetyl-coenzyme A transporter 1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_8182604_4	1122970.AUHC01000009_gene215	3.45e-32	125.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,2U30N@28211|Alphaproteobacteria,2K5ES@204457|Sphingomonadales	204457|Sphingomonadales	EG	EamA-like transporter family	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
WH3_k127_8232741_1	1121918.ARWE01000001_gene3062	1.092e-22	98.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42MVK@68525|delta/epsilon subdivisions,2WKEN@28221|Deltaproteobacteria,43TYG@69541|Desulfuromonadales	28221|Deltaproteobacteria	EI	Methylmalonyl-CoA mutase	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
WH3_k127_8232741_0	314278.NB231_09623	5.939e-202	634.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1T3U5@1236|Gammaproteobacteria,1X1MF@135613|Chromatiales	135613|Chromatiales	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
WH3_k127_8347129_3	1479239.JQMU01000001_gene1750	2.329e-31	124.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,2TR5F@28211|Alphaproteobacteria,2K04J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wecC	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH3_k127_8347129_0	279238.Saro_3221	3.45e-210	662.0	COG0438@1|root,COG0438@2|Bacteria,1PDZE@1224|Proteobacteria,2TR1N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4
WH3_k127_8347129_1	279238.Saro_3220	1.31e-177	566.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2K8J1@204457|Sphingomonadales	204457|Sphingomonadales	M	UDP binding domain	-	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH3_k127_8347129_2	1248917.ANFX01000035_gene1970	3.831e-130	420.0	COG1218@1|root,COG1218@2|Bacteria,1MY0Z@1224|Proteobacteria,2TQWF@28211|Alphaproteobacteria,2K0NZ@204457|Sphingomonadales	204457|Sphingomonadales	P	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
WH3_k127_8347129_4	1479239.JQMU01000001_gene1754	1.849e-30	120.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,2K22T@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2
WH3_k127_836216_0	383381.EH30_11390	1.655e-293	904.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,2K0B7@204457|Sphingomonadales	204457|Sphingomonadales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
WH3_k127_8418336_2	1248917.ANFX01000027_gene1069	1.701e-53	189.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,2K28K@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WH3_k127_8418336_3	291985.CCSI01000001_gene1794	2.871e-13	70.0	2EKY3@1|root,33EMM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	KOW
WH3_k127_8418336_0	1479239.JQMU01000001_gene525	6.453e-305	942.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2K061@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
WH3_k127_8418336_1	1479239.JQMU01000001_gene523	3.298e-63	217.0	COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria,2K05F@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WH3_k127_8432016_2	1479239.JQMU01000001_gene457	3.135e-50	181.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2U05U@28211|Alphaproteobacteria,2K1IQ@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WH3_k127_8432016_1	1479239.JQMU01000001_gene458	6.714e-144	460.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,2K1PV@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
WH3_k127_8432016_0	1248917.ANFX01000037_gene2178	4.81e-163	518.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,2K0WZ@204457|Sphingomonadales	204457|Sphingomonadales	J	2-methylthioadenine	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
WH3_k127_8447839_1	1479239.JQMU01000001_gene2810	6.233e-105	342.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,2K01J@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
WH3_k127_8447839_0	1248917.ANFX01000031_gene2574	3.355e-208	649.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,2JZYY@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WH3_k127_8454164_3	1479239.JQMU01000001_gene2028	2.552e-169	531.0	2DB77@1|root,2Z7K3@2|Bacteria,1NHMC@1224|Proteobacteria,2U06K@28211|Alphaproteobacteria,2K1RB@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the reaction center PufL M PsbA D family	pufL	-	-	-	-	-	-	-	-	-	-	-	Photo_RC
WH3_k127_8454164_2	1122970.AUHC01000004_gene2272	4.534e-206	641.0	2DBBD@1|root,2Z87P@2|Bacteria,1MWZI@1224|Proteobacteria,2TT76@28211|Alphaproteobacteria,2K2SW@204457|Sphingomonadales	204457|Sphingomonadales	C	The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis	-	-	-	ko:K08929	ko02020,map02020	M00597	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Photo_RC
WH3_k127_8454164_5	1479239.JQMU01000001_gene2026	3.514e-36	147.0	297GI@1|root,2ZUPU@2|Bacteria,1N9UR@1224|Proteobacteria,2UIW7@28211|Alphaproteobacteria,2K6V3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8454164_4	1479239.JQMU01000001_gene2025	1.001e-91	310.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2U8I1@28211|Alphaproteobacteria,2K4VZ@204457|Sphingomonadales	204457|Sphingomonadales	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
WH3_k127_8454164_0	1479239.JQMU01000001_gene2024	8.504e-247	766.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2TVK0@28211|Alphaproteobacteria,2K22X@204457|Sphingomonadales	204457|Sphingomonadales	C	geranylgeranyl reductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2
WH3_k127_8454164_1	1479239.JQMU01000001_gene2023	3.945e-212	666.0	COG2211@1|root,COG2211@2|Bacteria,1MWE4@1224|Proteobacteria,2TQY7@28211|Alphaproteobacteria,2K1IR@204457|Sphingomonadales	204457|Sphingomonadales	G	PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
WH3_k127_8478979_1	1479239.JQMU01000001_gene2343	1.512e-155	492.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria,2K14F@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WH3_k127_8478979_2	1248917.ANFX01000008_gene398	5.684e-05	46.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,2JZYV@204457|Sphingomonadales	204457|Sphingomonadales	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
WH3_k127_8478979_0	1479239.JQMU01000001_gene2344	7.942e-240	745.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,2K0J1@204457|Sphingomonadales	204457|Sphingomonadales	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WH3_k127_848035_2	1248917.ANFX01000040_gene776	7.621e-111	358.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,2K04G@204457|Sphingomonadales	204457|Sphingomonadales	C	Methylmalonate-semialdehyde dehydrogenase	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WH3_k127_848035_1	1479239.JQMU01000001_gene899	8.249e-157	496.0	COG2266@1|root,COG2266@2|Bacteria,1RJGN@1224|Proteobacteria,2TXT6@28211|Alphaproteobacteria,2K4U4@204457|Sphingomonadales	204457|Sphingomonadales	H	Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
WH3_k127_848035_0	1479239.JQMU01000001_gene900	3.744e-160	510.0	COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,2U6PC@28211|Alphaproteobacteria,2K0Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WH3_k127_849790_0	1479239.JQMU01000001_gene285	0.0	1121.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,2K0MC@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent DNA helicase RecG	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WH3_k127_849790_2	1479239.JQMU01000001_gene286	1.016e-51	183.0	COG2938@1|root,COG2938@2|Bacteria,1N6SJ@1224|Proteobacteria,2VCGJ@28211|Alphaproteobacteria,2K5W5@204457|Sphingomonadales	204457|Sphingomonadales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
WH3_k127_849790_1	1479239.JQMU01000001_gene287	0.0	1032.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2K07V@204457|Sphingomonadales	204457|Sphingomonadales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WH3_k127_8501294_0	1479239.JQMU01000001_gene2538	0.0	996.0	COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria,2K1S0@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
WH3_k127_8501294_1	1479239.JQMU01000001_gene2539	3.529e-121	392.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2U773@28211|Alphaproteobacteria,2K1IN@204457|Sphingomonadales	204457|Sphingomonadales	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
WH3_k127_8501294_2	1122970.AUHC01000005_gene1824	5.012e-88	297.0	COG5455@1|root,COG5455@2|Bacteria,1RJVB@1224|Proteobacteria,2U9H6@28211|Alphaproteobacteria,2K5B9@204457|Sphingomonadales	204457|Sphingomonadales	S	Nickel/cobalt transporter regulator	-	-	-	-	-	-	-	-	-	-	-	-	RcnB
WH3_k127_8532980_2	1479239.JQMU01000001_gene2581	5.31e-18	85.0	COG0457@1|root,COG0457@2|Bacteria,1PDUB@1224|Proteobacteria,2TTYN@28211|Alphaproteobacteria,2K0P8@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_21
WH3_k127_8532980_0	1479239.JQMU01000001_gene2582	2.438e-168	533.0	COG0385@1|root,COG0385@2|Bacteria,1MUMM@1224|Proteobacteria,2TU7J@28211|Alphaproteobacteria,2K0HH@204457|Sphingomonadales	204457|Sphingomonadales	S	Bile acid sodium symporter	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
WH3_k127_8532980_1	1122970.AUHC01000001_gene364	5.061e-67	229.0	COG2899@1|root,COG2899@2|Bacteria,1NURT@1224|Proteobacteria,2TRRF@28211|Alphaproteobacteria,2K23U@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09799	-	-	-	-	ko00000	-	-	-	DUF475
WH3_k127_8540199_8	1248917.ANFX01000032_gene963	1.693e-72	254.0	2DHC3@1|root,2ZZ6X@2|Bacteria,1PNCF@1224|Proteobacteria,2V0YE@28211|Alphaproteobacteria,2KAXK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8540199_0	1479239.JQMU01000001_gene773	0.0	1409.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2TS8V@28211|Alphaproteobacteria,2K03T@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WH3_k127_8540199_4	1479239.JQMU01000001_gene772	2.636e-125	404.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2TS0J@28211|Alphaproteobacteria,2JZZV@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_8540199_6	1248917.ANFX01000032_gene960	5.417e-106	349.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria,2K1U9@204457|Sphingomonadales	204457|Sphingomonadales	E	COG2755 Lysophospholipase L1 and related esterases	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
WH3_k127_8540199_1	1479239.JQMU01000001_gene770	2.752e-199	631.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,2K0WV@204457|Sphingomonadales	204457|Sphingomonadales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WH3_k127_8540199_9	1479239.JQMU01000001_gene768	1.371e-33	132.0	COG1983@1|root,COG1983@2|Bacteria,1NGIB@1224|Proteobacteria,2UJTZ@28211|Alphaproteobacteria,2K7KQ@204457|Sphingomonadales	204457|Sphingomonadales	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
WH3_k127_8540199_2	1479239.JQMU01000001_gene767	2.469e-155	491.0	COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria,2K3ER@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_8540199_7	1248917.ANFX01000032_gene954	1.569e-105	344.0	COG0494@1|root,COG0494@2|Bacteria,1RE72@1224|Proteobacteria,2U805@28211|Alphaproteobacteria,2K4H0@204457|Sphingomonadales	204457|Sphingomonadales	L	Nudix hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WH3_k127_8540199_5	1479239.JQMU01000001_gene765	3.301e-123	398.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,2K470@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
WH3_k127_8540199_3	1479239.JQMU01000001_gene764	5.713e-135	434.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,2K1AR@204457|Sphingomonadales	204457|Sphingomonadales	S	Methanol dehydrogenase	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
WH3_k127_8555973_1	1248917.ANFX01000014_gene1358	5.803e-142	452.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TSIF@28211|Alphaproteobacteria,2K209@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WH3_k127_8555973_0	1479239.JQMU01000001_gene963	1.035e-168	534.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2U1B8@28211|Alphaproteobacteria,2K5DP@204457|Sphingomonadales	204457|Sphingomonadales	I	Steryl acetyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WH3_k127_8555973_2	1248917.ANFX01000014_gene1355	3.805e-78	265.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2TQSI@28211|Alphaproteobacteria,2K1FA@204457|Sphingomonadales	204457|Sphingomonadales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
WH3_k127_8562188_4	1248917.ANFX01000013_gene1562	5.648e-16	79.0	COG1668@1|root,COG1668@2|Bacteria,1MWAS@1224|Proteobacteria,2TU2K@28211|Alphaproteobacteria,2K1E9@204457|Sphingomonadales	204457|Sphingomonadales	CP	ABC-type Na efflux pump, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WH3_k127_8562188_3	1479239.JQMU01000001_gene1246	2.215e-190	597.0	COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria,2TW40@28211|Alphaproteobacteria,2JZWA@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WH3_k127_8562188_2	383381.EH30_14285	9.779e-194	608.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,2K0HW@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
WH3_k127_8562188_1	1248917.ANFX01000013_gene1565	1.101e-240	747.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2TW0G@28211|Alphaproteobacteria,2KEE3@204457|Sphingomonadales	204457|Sphingomonadales	C	Reductase C-terminal	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
WH3_k127_8562188_0	1479239.JQMU01000001_gene1249	0.0	1594.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2K0WP@204457|Sphingomonadales	204457|Sphingomonadales	E	glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
WH3_k127_8565984_3	1479239.JQMU01000001_gene1968	5.485e-73	247.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,2U5D2@28211|Alphaproteobacteria,2K0TS@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
WH3_k127_8565984_1	1479239.JQMU01000001_gene1966	3.714e-138	445.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria,2K1WW@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
WH3_k127_8565984_0	1479239.JQMU01000001_gene1965	6.095e-266	821.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,2K1AN@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WH3_k127_8565984_2	1479239.JQMU01000001_gene1964	3.979e-107	350.0	2DR92@1|root,33ARB@2|Bacteria,1QYNQ@1224|Proteobacteria,2TXT3@28211|Alphaproteobacteria,2KEJC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8586699_1	1479239.JQMU01000001_gene1724	7.236e-66	227.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,2U2YW@28211|Alphaproteobacteria,2K0HY@204457|Sphingomonadales	204457|Sphingomonadales	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
WH3_k127_8586699_0	1122970.AUHC01000002_gene1163	8.002e-258	802.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales	204457|Sphingomonadales	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WH3_k127_8589802_3	1248917.ANFX01000014_gene1385	2.31e-58	202.0	COG3239@1|root,COG3239@2|Bacteria,1MVY5@1224|Proteobacteria,2U156@28211|Alphaproteobacteria,2K0CR@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
WH3_k127_8589802_1	1248917.ANFX01000014_gene1386	2.951e-93	312.0	COG0454@1|root,COG0456@2|Bacteria,1MZIE@1224|Proteobacteria,2UHRP@28211|Alphaproteobacteria,2K5C4@204457|Sphingomonadales	204457|Sphingomonadales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
WH3_k127_8589802_0	1479239.JQMU01000001_gene934	8.638e-200	626.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,2K1ZM@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WH3_k127_8589802_2	1479239.JQMU01000001_gene933	7.438e-71	241.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2U55Q@28211|Alphaproteobacteria,2K07C@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WH3_k127_8589829_2	1248917.ANFX01000020_gene2238	9.936e-55	192.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria,2K1KV@204457|Sphingomonadales	204457|Sphingomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WH3_k127_8589829_3	1122970.AUHC01000002_gene1497	1.265e-44	166.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2UBU3@28211|Alphaproteobacteria,2K5ZV@204457|Sphingomonadales	204457|Sphingomonadales	E	Phosphoribosyl-ATP	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
WH3_k127_8589829_1	1248917.ANFX01000020_gene2236	9.21e-74	250.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,2K4G2@204457|Sphingomonadales	204457|Sphingomonadales	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WH3_k127_8589829_0	1479239.JQMU01000001_gene2140	2.324e-88	297.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2UBYM@28211|Alphaproteobacteria,2K4JS@204457|Sphingomonadales	204457|Sphingomonadales	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
WH3_k127_8596084_1	1479239.JQMU01000001_gene1571	4.533e-164	517.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,2K20E@204457|Sphingomonadales	204457|Sphingomonadales	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WH3_k127_8596084_0	1248917.ANFX01000019_gene2329	4.238e-181	568.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2K21X@204457|Sphingomonadales	204457|Sphingomonadales	L	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N_2,ADH_zinc_N
WH3_k127_8613453_2	1122970.AUHC01000001_gene562	3.382e-84	288.0	COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,2K0XJ@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane metal-binding protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
WH3_k127_8613453_0	1248917.ANFX01000010_gene200	1.064e-288	890.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,2K09A@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WH3_k127_8613453_1	1122970.AUHC01000001_gene564	2.607e-149	474.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2K0JS@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WH3_k127_8673985_1	1248917.ANFX01000029_gene2707	4.724e-111	362.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria,2K0SN@204457|Sphingomonadales	204457|Sphingomonadales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
WH3_k127_8673985_0	1479239.JQMU01000001_gene1797	1.479e-306	946.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,2K1E1@204457|Sphingomonadales	204457|Sphingomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WH3_k127_8673985_3	1479239.JQMU01000001_gene1796	5.3e-40	151.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2K625@204457|Sphingomonadales	204457|Sphingomonadales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WH3_k127_8673985_2	1248917.ANFX01000029_gene2710	1.241e-62	216.0	COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,2K5Y4@204457|Sphingomonadales	204457|Sphingomonadales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WH3_k127_8683360_1	1248917.ANFX01000027_gene1121	3.579e-130	416.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2TYHX@28211|Alphaproteobacteria,2K0ZW@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.5.7	ko:K01502	ko00643,ko01120,map00643,map01120	-	R05358	RC01336	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WH3_k127_8683360_0	1479239.JQMU01000001_gene211	1.775e-135	439.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,2JZVZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WH3_k127_8683360_3	1248917.ANFX01000030_gene479	2.386e-65	225.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,2K4GC@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WH3_k127_8683360_2	1248917.ANFX01000030_gene480	3.933e-119	385.0	COG1506@1|root,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,2TRVE@28211|Alphaproteobacteria,2K0U1@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
WH3_k127_8829541_2	1122970.AUHC01000001_gene712	5.247e-102	334.0	COG2267@1|root,COG2267@2|Bacteria,1QUNU@1224|Proteobacteria,2TW29@28211|Alphaproteobacteria,2K09G@204457|Sphingomonadales	204457|Sphingomonadales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WH3_k127_8829541_1	1479239.JQMU01000001_gene203	2.814e-156	502.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria,2K2W8@204457|Sphingomonadales	204457|Sphingomonadales	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,PQQ_2
WH3_k127_8829541_3	1479239.JQMU01000001_gene202	1.161e-75	258.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,2UC5Z@28211|Alphaproteobacteria,2K6SX@204457|Sphingomonadales	204457|Sphingomonadales	O	Ribosomal protein S6 modification protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
WH3_k127_8829541_0	1479239.JQMU01000001_gene201	1.432e-185	581.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,2TRUH@28211|Alphaproteobacteria,2K29D@204457|Sphingomonadales	204457|Sphingomonadales	HJ	Belongs to the RimK family	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
WH3_k127_8829541_4	1248917.ANFX01000030_gene492	6.226e-46	166.0	COG1028@1|root,COG1028@2|Bacteria,1MX8B@1224|Proteobacteria,2U26N@28211|Alphaproteobacteria,2K38N@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_8860103_0	1248760.ANFZ01000009_gene1366	3.411e-111	380.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2TT0E@28211|Alphaproteobacteria,2K188@204457|Sphingomonadales	204457|Sphingomonadales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WH3_k127_886544_1	1479239.JQMU01000001_gene2453	2.653e-132	422.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,2K2TY@204457|Sphingomonadales	204457|Sphingomonadales	Q	Retinal pigment epithelial membrane protein	-	-	1.13.11.82	ko:K11159,ko:K21822	-	-	-	-	ko00000,ko01000	-	-	-	RPE65
WH3_k127_886544_0	1248917.ANFX01000037_gene2013	4e-323	996.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0GU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WH3_k127_886544_2	1479239.JQMU01000001_gene2452	1.885e-56	199.0	COG2885@1|root,COG2885@2|Bacteria,1R5IS@1224|Proteobacteria,2U2V8@28211|Alphaproteobacteria,2K1H8@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WH3_k127_8876572_0	383381.EH30_04420	5.484e-207	644.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,2K0B0@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WH3_k127_8876572_1	1123267.JONN01000001_gene609	1.976e-45	169.0	2CM2H@1|root,32SDI@2|Bacteria,1NPEY@1224|Proteobacteria,2UJZ9@28211|Alphaproteobacteria,2K430@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
WH3_k127_8876572_2	1479239.JQMU01000001_gene1138	1.094e-12	68.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,2U5TA@28211|Alphaproteobacteria,2K48I@204457|Sphingomonadales	204457|Sphingomonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WH3_k127_8912803_0	1479239.JQMU01000001_gene250	0.0	1459.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,2K04E@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WH3_k127_8912803_1	1248917.ANFX01000027_gene1079	7.874e-108	355.0	COG3000@1|root,COG3000@2|Bacteria,1RKDE@1224|Proteobacteria,2U7RM@28211|Alphaproteobacteria,2KD9X@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH3_k127_8912803_2	1479239.JQMU01000001_gene251	2.646e-19	91.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0CY@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
WH3_k127_8913920_0	1479239.JQMU01000001_gene719	3.086e-240	743.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,2K0DV@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
WH3_k127_8913920_1	1479239.JQMU01000001_gene720	1.042e-164	522.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,2K23F@204457|Sphingomonadales	204457|Sphingomonadales	S	Deoxyribodipyrimidine photo-lyase	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
WH3_k127_8915077_2	1122970.AUHC01000007_gene1715	5.975e-31	122.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TSA0@28211|Alphaproteobacteria,2K081@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_8915077_1	237727.NAP1_00600	1.115e-122	398.0	COG3751@1|root,COG3751@2|Bacteria,1MYBU@1224|Proteobacteria,2UAT5@28211|Alphaproteobacteria,2K2VM@204457|Sphingomonadales	204457|Sphingomonadales	O	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_4
WH3_k127_8915077_0	237727.NAP1_00595	2.471e-180	576.0	COG3063@1|root,COG3063@2|Bacteria,1QUNN@1224|Proteobacteria,2TW22@28211|Alphaproteobacteria,2KE93@204457|Sphingomonadales	204457|Sphingomonadales	NU	Putative 2OG-Fe(II) oxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5,TPR_16,TPR_19
WH3_k127_8941235_1	1248917.ANFX01000031_gene2560	4.2e-163	519.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K0FQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_8941235_0	1479239.JQMU01000001_gene2822	6.61e-288	887.0	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,2TR9T@28211|Alphaproteobacteria,2K0D6@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.68	ko:K00154	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
WH3_k127_8941235_2	517722.AEUE01000006_gene1718	1.66e-136	449.0	COG3391@1|root,COG3391@2|Bacteria,1NC58@1224|Proteobacteria,2UFDR@28211|Alphaproteobacteria,2K5SA@204457|Sphingomonadales	204457|Sphingomonadales	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8941235_5	1479239.JQMU01000001_gene2821	1.833e-76	258.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria,2K4KM@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WH3_k127_8941235_3	1479239.JQMU01000001_gene2820	2.056e-108	356.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2TQK3@28211|Alphaproteobacteria,2K0KE@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
WH3_k127_8941235_4	1479239.JQMU01000001_gene2819	3.501e-101	332.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2TSMT@28211|Alphaproteobacteria,2K0IR@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
WH3_k127_8951473_0	1479239.JQMU01000001_gene342	5.479e-121	389.0	2DB9X@1|root,2Z7ZS@2|Bacteria,1N6CK@1224|Proteobacteria,2U2ME@28211|Alphaproteobacteria,2K3K7@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3445)	-	-	1.14.13.238	ko:K22342	-	-	-	-	ko00000,ko01000	-	-	-	DUF3445
WH3_k127_8951473_3	1479239.JQMU01000001_gene341	1.837e-45	172.0	COG3755@1|root,COG3755@2|Bacteria,1N8EC@1224|Proteobacteria,2UFJC@28211|Alphaproteobacteria,2K6SA@204457|Sphingomonadales	204457|Sphingomonadales	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
WH3_k127_8951473_1	1479239.JQMU01000001_gene340	3.644e-61	212.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,2K050@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl propionyl-CoA carboxylase, alpha subunit	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
WH3_k127_8952067_4	1122970.AUHC01000011_gene2707	7.465e-84	278.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2K2HH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WH3_k127_8952067_1	1248917.ANFX01000019_gene2325	1.064e-196	618.0	COG1960@1|root,COG1960@2|Bacteria,1RB6Y@1224|Proteobacteria,2U6T6@28211|Alphaproteobacteria,2KCQ9@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_8952067_3	1479239.JQMU01000001_gene1565	3.028e-85	282.0	COG1545@1|root,COG1545@2|Bacteria,1N3B8@1224|Proteobacteria,2UEKY@28211|Alphaproteobacteria,2KDP4@204457|Sphingomonadales	204457|Sphingomonadales	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	OB_aCoA_assoc
WH3_k127_8952067_0	1479239.JQMU01000001_gene1564	1.188e-247	769.0	COG0183@1|root,COG0183@2|Bacteria,1R5AW@1224|Proteobacteria,2U1UK@28211|Alphaproteobacteria,2K1A4@204457|Sphingomonadales	204457|Sphingomonadales	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
WH3_k127_8952067_2	1479239.JQMU01000001_gene1563	5.167e-130	418.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VFFP@28211|Alphaproteobacteria,2KDWM@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_8952857_0	1479239.JQMU01000001_gene2204	0.0	1565.0	COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,2U4DF@28211|Alphaproteobacteria,2K18I@204457|Sphingomonadales	204457|Sphingomonadales	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WH3_k127_8952857_2	1479239.JQMU01000001_gene2205	1.667e-170	537.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5HA@28211|Alphaproteobacteria,2K0A3@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
WH3_k127_8952857_1	1479239.JQMU01000001_gene2206	0.0	1000.0	COG1716@1|root,COG1716@2|Bacteria,1R72N@1224|Proteobacteria,2U42V@28211|Alphaproteobacteria,2K0ZA@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
WH3_k127_8952857_3	1248917.ANFX01000012_gene1794	4.178e-17	80.0	29W19@1|root,30HJP@2|Bacteria,1R60N@1224|Proteobacteria,2TV4D@28211|Alphaproteobacteria,2K2WI@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8953952_0	1248917.ANFX01000024_gene1126	2.021e-235	730.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,2K0V7@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WH3_k127_8953952_1	1248917.ANFX01000024_gene1125	1.118e-172	548.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2K9SG@204457|Sphingomonadales	204457|Sphingomonadales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WH3_k127_8953952_2	1248917.ANFX01000024_gene1124	5.084e-86	286.0	COG3967@1|root,COG3967@2|Bacteria,1QSYJ@1224|Proteobacteria,2UBZS@28211|Alphaproteobacteria,2K48U@204457|Sphingomonadales	204457|Sphingomonadales	M	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
WH3_k127_8957168_0	1479239.JQMU01000001_gene1601	1.359e-233	724.0	COG1960@1|root,COG1960@2|Bacteria,1MX17@1224|Proteobacteria,2TTRE@28211|Alphaproteobacteria,2K20J@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_8957168_3	1479239.JQMU01000001_gene1602	3.49e-82	275.0	COG3402@1|root,COG3402@2|Bacteria,1N8GD@1224|Proteobacteria,2UEFP@28211|Alphaproteobacteria,2K6MN@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
WH3_k127_8957168_1	1248917.ANFX01000019_gene2361	1.866e-225	711.0	COG3428@1|root,COG3428@2|Bacteria,1RI8G@1224|Proteobacteria,2VGGB@28211|Alphaproteobacteria,2KE3P@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
WH3_k127_8957168_5	1385517.N800_12195	1.247e-06	56.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria,1SH12@1236|Gammaproteobacteria,1X83J@135614|Xanthomonadales	135614|Xanthomonadales	S	acetyltransferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
WH3_k127_8957168_2	1479239.JQMU01000001_gene1605	5.413e-189	593.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,2K0EJ@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WH3_k127_8957168_4	1479239.JQMU01000001_gene1606	1.926e-16	80.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria,2K0J7@204457|Sphingomonadales	204457|Sphingomonadales	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WH3_k127_8958207_2	555793.WSK_1475	4.216e-12	68.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,2K1YP@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
WH3_k127_8958207_1	1479239.JQMU01000001_gene1263	5.703e-169	553.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,2K1YP@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
WH3_k127_8958207_0	1248917.ANFX01000013_gene1582	2.373e-209	677.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2K04D@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WH3_k127_8960415_3	1479239.JQMU01000001_gene2111	2.207e-37	142.0	COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,2K0A1@204457|Sphingomonadales	204457|Sphingomonadales	S	GcrA cell cycle regulator	-	-	-	ko:K13583	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	GcrA
WH3_k127_8960415_0	1479239.JQMU01000001_gene2112	4.187e-161	517.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,2K23E@204457|Sphingomonadales	204457|Sphingomonadales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WH3_k127_8960415_2	1248917.ANFX01000042_gene1708	3.724e-70	243.0	2AHIG@1|root,317W2@2|Bacteria,1NM0G@1224|Proteobacteria,2UNI2@28211|Alphaproteobacteria,2KAN6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8960415_1	1248917.ANFX01000042_gene1709	1.329e-76	257.0	COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,2U9MS@28211|Alphaproteobacteria,2K54K@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA-binding protein	-	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
WH3_k127_8966207_1	1479239.JQMU01000001_gene1305	2.321e-68	233.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2U17R@28211|Alphaproteobacteria,2K18P@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,OMP_b-brl,OmpA
WH3_k127_8966207_2	1044.EH31_01490	1.776e-66	234.0	2EGK3@1|root,33AC8@2|Bacteria,1R3C0@1224|Proteobacteria,2U008@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8966207_0	702113.PP1Y_Mpl6100	1.075e-115	387.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K0KA@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
WH3_k127_8969110_0	1479239.JQMU01000001_gene352	1.032e-260	810.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0U4@204457|Sphingomonadales	204457|Sphingomonadales	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WH3_k127_8969110_1	1331060.RLDS_17380	6.942e-07	58.0	COG0810@1|root,COG0810@2|Bacteria,1NYVY@1224|Proteobacteria,2UTB0@28211|Alphaproteobacteria,2K726@204457|Sphingomonadales	204457|Sphingomonadales	M	Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WH3_k127_8986504_9	1479239.JQMU01000001_gene1210	4.238e-69	245.0	COG4704@1|root,COG4704@2|Bacteria,1N6RE@1224|Proteobacteria,2UGGS@28211|Alphaproteobacteria,2KCA0@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
WH3_k127_8986504_3	1479239.JQMU01000001_gene1209	6.221e-156	494.0	COG3000@1|root,COG3000@2|Bacteria,1NXAF@1224|Proteobacteria,2TRF0@28211|Alphaproteobacteria,2K0X1@204457|Sphingomonadales	204457|Sphingomonadales	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WH3_k127_8986504_7	1479239.JQMU01000001_gene1208	3.361e-82	276.0	COG5321@1|root,COG5321@2|Bacteria,1RDXW@1224|Proteobacteria,2U73Y@28211|Alphaproteobacteria,2K5GG@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA repair protein MmcB-like	-	-	-	-	-	-	-	-	-	-	-	-	MmcB-like
WH3_k127_8986504_10	1479239.JQMU01000001_gene1207	8.846e-32	128.0	2DHUM@1|root,3010J@2|Bacteria,1P10Y@1224|Proteobacteria,2UVE6@28211|Alphaproteobacteria,2KB2Z@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8986504_6	1479239.JQMU01000001_gene1328	3.285e-105	344.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2U5H3@28211|Alphaproteobacteria,2K0BZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
WH3_k127_8986504_1	279238.Saro_2915	6.024e-162	512.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2TU5K@28211|Alphaproteobacteria,2K2Y4@204457|Sphingomonadales	204457|Sphingomonadales	S	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
WH3_k127_8986504_4	1479239.JQMU01000001_gene1221	1.594e-129	422.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2U2E9@28211|Alphaproteobacteria,2K0ED@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WH3_k127_8986504_0	1479239.JQMU01000001_gene1223	3.56e-175	554.0	COG1597@1|root,COG1597@2|Bacteria,1RBR2@1224|Proteobacteria,2U66B@28211|Alphaproteobacteria,2KCCZ@204457|Sphingomonadales	204457|Sphingomonadales	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WH3_k127_8986504_2	1479239.JQMU01000001_gene1224	9.656e-157	501.0	COG1597@1|root,COG1597@2|Bacteria,1RB97@1224|Proteobacteria,2TW41@28211|Alphaproteobacteria,2KEA6@204457|Sphingomonadales	204457|Sphingomonadales	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8986504_8	1479239.JQMU01000001_gene1225	1.826e-76	261.0	COG4704@1|root,COG4704@2|Bacteria,1REQD@1224|Proteobacteria,2U8UI@28211|Alphaproteobacteria,2K510@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
WH3_k127_8986504_5	1479239.JQMU01000001_gene1226	1.042e-125	404.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,2K1ZB@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WH3_k127_8988075_2	1248917.ANFX01000012_gene1847	1.008e-174	550.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,2JZUV@204457|Sphingomonadales	204457|Sphingomonadales	G	beta-N-acetylhexosaminidase	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
WH3_k127_8988075_4	1479239.JQMU01000001_gene2254	1.797e-97	326.0	COG3115@1|root,COG3115@2|Bacteria,1RJNQ@1224|Proteobacteria,2UC30@28211|Alphaproteobacteria,2K2NX@204457|Sphingomonadales	204457|Sphingomonadales	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
WH3_k127_8988075_0	1248917.ANFX01000012_gene1845	0.0	1034.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,2K0G5@204457|Sphingomonadales	204457|Sphingomonadales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1,tRNA-synt_1d,tRNA-synt_1f
WH3_k127_8988075_3	1479239.JQMU01000001_gene2252	1.555e-107	351.0	2B5IK@1|root,31YDD@2|Bacteria,1RAZF@1224|Proteobacteria,2U6F0@28211|Alphaproteobacteria,2K43H@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_8988075_1	1479239.JQMU01000001_gene2251	8.034e-194	607.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2TRNR@28211|Alphaproteobacteria,2K1ES@204457|Sphingomonadales	204457|Sphingomonadales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
WH3_k127_8988075_5	1479239.JQMU01000001_gene2250	2.982e-56	200.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2TS6D@28211|Alphaproteobacteria,2K09Q@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
WH3_k127_9026685_4	237727.NAP1_14473	4.74e-14	75.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_2,TonB_C
WH3_k127_9026685_2	1248917.ANFX01000037_gene2189	3.37e-177	557.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,2K012@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
WH3_k127_9026685_1	1479239.JQMU01000001_gene447	1.418e-246	763.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,2TSQM@28211|Alphaproteobacteria,2K0ID@204457|Sphingomonadales	204457|Sphingomonadales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WH3_k127_9026685_0	1248917.ANFX01000037_gene2191	0.0	1137.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria,2K0PT@204457|Sphingomonadales	204457|Sphingomonadales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WH3_k127_9026685_3	1449076.JOOE01000002_gene1004	3.117e-52	186.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,2TURU@28211|Alphaproteobacteria,2K3HN@204457|Sphingomonadales	204457|Sphingomonadales	E	Homocysteine S-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	S-methyl_trans
WH3_k127_9036554_8	1122970.AUHC01000010_gene1644	1.261e-09	58.0	COG3827@1|root,COG3827@2|Bacteria,1NH58@1224|Proteobacteria,2VCF9@28211|Alphaproteobacteria,2K6DD@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2497)	-	-	-	ko:K09991	-	-	-	-	ko00000	-	-	-	DUF2497
WH3_k127_9036554_0	1479239.JQMU01000001_gene1446	0.0	1176.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,2K16Q@204457|Sphingomonadales	204457|Sphingomonadales	EU	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WH3_k127_9036554_3	1479239.JQMU01000001_gene1445	3.302e-71	246.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2UKJ0@28211|Alphaproteobacteria,2K6PG@204457|Sphingomonadales	204457|Sphingomonadales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9036554_7	1479239.JQMU01000001_gene1444	2.741e-47	172.0	2ACU7@1|root,312F7@2|Bacteria,1N510@1224|Proteobacteria,2UDTR@28211|Alphaproteobacteria,2K6VE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9036554_4	1479239.JQMU01000001_gene1443	1.841e-68	239.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,2K5EC@204457|Sphingomonadales	204457|Sphingomonadales	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WH3_k127_9036554_5	1248917.ANFX01000005_gene148	9.84e-56	196.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,2K54P@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the HesB IscA family	erpA	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
WH3_k127_9036554_1	1479239.JQMU01000001_gene1441	1.525e-164	520.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,2K0HF@204457|Sphingomonadales	204457|Sphingomonadales	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WH3_k127_9036554_2	1479239.JQMU01000001_gene1440	7.38e-85	286.0	COG3773@1|root,COG3773@2|Bacteria,1RDSV@1224|Proteobacteria,2U8XY@28211|Alphaproteobacteria,2K4PG@204457|Sphingomonadales	204457|Sphingomonadales	M	COG3773 Cell wall hydrolyses involved in spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
WH3_k127_9036554_6	1479239.JQMU01000001_gene1439	1.137e-48	175.0	COG5447@1|root,COG5447@2|Bacteria,1N1KU@1224|Proteobacteria,2UFES@28211|Alphaproteobacteria,2K70S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1491)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1491
WH3_k127_9039488_4	504472.Slin_4991	3.714e-15	80.0	COG2603@1|root,COG2603@2|Bacteria,4NH7W@976|Bacteroidetes,47KFW@768503|Cytophagia	976|Bacteroidetes	S	Rhodanese Homology Domain	-	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
WH3_k127_9039488_1	1479239.JQMU01000001_gene1827	4.651e-55	206.0	2C19Z@1|root,2Z826@2|Bacteria,1RBG1@1224|Proteobacteria,2UKHV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9039488_0	1479239.JQMU01000001_gene1826	0.0	1517.0	COG0308@1|root,COG0308@2|Bacteria,1MUV3@1224|Proteobacteria,2TVKQ@28211|Alphaproteobacteria,2K1RS@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WH3_k127_9039488_2	1479239.JQMU01000001_gene1825	4.788e-29	118.0	COG2102@1|root,COG2102@2|Bacteria,1R97Y@1224|Proteobacteria,2VCJ1@28211|Alphaproteobacteria,2KBXQ@204457|Sphingomonadales	204457|Sphingomonadales	S	of PP-loop superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9039488_3	1248917.ANFX01000033_gene725	2.176e-25	106.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,2K04T@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WH3_k127_9049566_7	1248917.ANFX01000037_gene2108	7.925e-104	338.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2TQT2@28211|Alphaproteobacteria,2K2TX@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH dehydrogenase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WH3_k127_9049566_9	1479239.JQMU01000001_gene270	2.575e-91	301.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2TTCK@28211|Alphaproteobacteria,2K44J@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
WH3_k127_9049566_0	1479239.JQMU01000001_gene271	7.2e-238	750.0	COG0642@1|root,COG0642@2|Bacteria,1RDQ3@1224|Proteobacteria,2U7I3@28211|Alphaproteobacteria,2KE9H@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA
WH3_k127_9049566_3	1479239.JQMU01000001_gene272	6.12e-165	523.0	COG0438@1|root,COG0438@2|Bacteria,1QWDV@1224|Proteobacteria,2TWWD@28211|Alphaproteobacteria,2KEHG@204457|Sphingomonadales	204457|Sphingomonadales	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9049566_14	1121355.KB903379_gene745	2.841e-06	50.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WH3_k127_9049566_4	1248917.ANFX01000040_gene764	4.432e-143	460.0	COG0598@1|root,COG0598@2|Bacteria,1MW8W@1224|Proteobacteria,2U2S4@28211|Alphaproteobacteria,2K1TZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Mg2 transporter protein, CorA family protein	-	-	-	ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.4	-	-	CorA
WH3_k127_9049566_1	1479239.JQMU01000001_gene2547	3.796e-189	594.0	COG2201@1|root,COG2201@2|Bacteria,1R721@1224|Proteobacteria,2U3C3@28211|Alphaproteobacteria,2JZXG@204457|Sphingomonadales	204457|Sphingomonadales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WH3_k127_9049566_5	1479239.JQMU01000001_gene2546	7.43e-128	425.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2K0BV@204457|Sphingomonadales	204457|Sphingomonadales	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
WH3_k127_9049566_13	1044.EH31_06895	2e-13	76.0	2C3Q3@1|root,2ZY9I@2|Bacteria,1NP1N@1224|Proteobacteria,2UKYD@28211|Alphaproteobacteria,2K89W@204457|Sphingomonadales	204457|Sphingomonadales	S	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
WH3_k127_9049566_2	1123270.ATUR01000002_gene2061	7.758e-176	577.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,2K08K@204457|Sphingomonadales	204457|Sphingomonadales	NT	CheA signal transduction histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
WH3_k127_9049566_8	1044.EH31_06905	1.286e-99	334.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2TRQ3@28211|Alphaproteobacteria,2K0HS@204457|Sphingomonadales	204457|Sphingomonadales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WH3_k127_9049566_6	1044.EH31_06910	2.105e-114	383.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2TSGV@28211|Alphaproteobacteria,2K085@204457|Sphingomonadales	204457|Sphingomonadales	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WH3_k127_9049566_10	1122612.AUBA01000014_gene238	1.801e-57	209.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2U864@28211|Alphaproteobacteria,2K4SM@204457|Sphingomonadales	204457|Sphingomonadales	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
WH3_k127_9049566_12	1044.EH31_06920	5.979e-54	192.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2UA4W@28211|Alphaproteobacteria,2K5CB@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WH3_k127_9049566_11	1044.EH31_06925	4.482e-56	197.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2UBA1@28211|Alphaproteobacteria,2KDA3@204457|Sphingomonadales	204457|Sphingomonadales	NT	CheW-like domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WH3_k127_9051138_0	1479239.JQMU01000001_gene308	7.891e-275	852.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,2K07I@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WH3_k127_9107016_1	1479239.JQMU01000001_gene2713	2.913e-126	405.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2K1EY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WH3_k127_9107016_0	1479239.JQMU01000001_gene2712	0.0	1142.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,2K1KK@204457|Sphingomonadales	204457|Sphingomonadales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WH3_k127_9107016_2	1479239.JQMU01000001_gene2711	2.435e-38	150.0	COG2847@1|root,COG2847@2|Bacteria,1ND53@1224|Proteobacteria,2UG2M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Pfam:DUF461	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
WH3_k127_9113059_0	1479239.JQMU01000001_gene156	1.932e-140	455.0	COG4219@1|root,COG4219@2|Bacteria,1R3YH@1224|Proteobacteria,2U67Y@28211|Alphaproteobacteria,2K1JQ@204457|Sphingomonadales	204457|Sphingomonadales	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
WH3_k127_9113059_1	1479239.JQMU01000001_gene155	1.208e-48	176.0	2DC1J@1|root,333E1@2|Bacteria,1N2JX@1224|Proteobacteria,2UE17@28211|Alphaproteobacteria,2K65P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9140027_0	1479239.JQMU01000001_gene2715	0.0	1017.0	COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2TU16@28211|Alphaproteobacteria,2K0ET@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3376)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3376,Patatin
WH3_k127_9141857_1	1248917.ANFX01000013_gene1487	3.814e-113	368.0	COG2271@1|root,COG2271@2|Bacteria,1MUEK@1224|Proteobacteria,2TS60@28211|Alphaproteobacteria,2K32T@204457|Sphingomonadales	204457|Sphingomonadales	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WH3_k127_9141857_0	1280953.HOC_03528	9.889e-147	484.0	COG3710@1|root,COG5616@1|root,COG3710@2|Bacteria,COG5616@2|Bacteria,1NSKC@1224|Proteobacteria,2TW11@28211|Alphaproteobacteria,440NM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	COG3710 DNA-binding winged-HTH domains	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
WH3_k127_9144306_0	1479239.JQMU01000001_gene1227	0.0	1008.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,2K1RQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Heparinase	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
WH3_k127_9144306_1	1479239.JQMU01000001_gene1226	1.834e-22	96.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,2K1ZB@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WH3_k127_9156604_0	666681.M301_0012	6.383e-07	63.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,2KMBV@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	HCBP_related,HemolysinCabind
WH3_k127_919590_4	1479239.JQMU01000001_gene861	1.021e-23	101.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2TS0S@28211|Alphaproteobacteria,2JZYN@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
WH3_k127_919590_6	1146883.BLASA_1191	2.171e-13	76.0	COG1917@1|root,COG1917@2|Bacteria,2IQ74@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_919590_1	279238.Saro_3152	8.387e-45	167.0	2D8VC@1|root,32TS1@2|Bacteria,1MZWT@1224|Proteobacteria,2UEVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_919590_0	1479239.JQMU01000001_gene859	2.999e-61	221.0	2AKZG@1|root,31BT4@2|Bacteria,1Q7R6@1224|Proteobacteria,2VDWQ@28211|Alphaproteobacteria,2K6B3@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3833
WH3_k127_919590_3	291985.CCSI01000006_gene1174	1.074e-33	139.0	COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,2UGX0@28211|Alphaproteobacteria,2KDAH@204457|Sphingomonadales	204457|Sphingomonadales	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
WH3_k127_919590_5	1479239.JQMU01000001_gene855	7.24e-17	81.0	2DCJU@1|root,2ZEF4@2|Bacteria,1P46H@1224|Proteobacteria,2UWRX@28211|Alphaproteobacteria,2KBW2@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_919590_2	1479239.JQMU01000001_gene854	2.921e-35	138.0	2AK1W@1|root,31ARH@2|Bacteria,1P57B@1224|Proteobacteria,2UXBA@28211|Alphaproteobacteria,2KBUG@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1278 Cold shock proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9327757_4	1479239.JQMU01000001_gene1485	8.099e-53	187.0	COG2010@1|root,COG2010@2|Bacteria,1REPJ@1224|Proteobacteria,2U87U@28211|Alphaproteobacteria,2K7G4@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
WH3_k127_9327757_2	1248917.ANFX01000013_gene1508	1.936e-109	361.0	2EQH5@1|root,33I35@2|Bacteria,1N2B2@1224|Proteobacteria,2UDX4@28211|Alphaproteobacteria,2K4K4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9327757_0	1479239.JQMU01000001_gene1484	2.428e-190	597.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2K0DX@204457|Sphingomonadales	204457|Sphingomonadales	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WH3_k127_9327757_3	1479239.JQMU01000001_gene1483	4.94e-85	288.0	COG2981@1|root,COG2981@2|Bacteria,1MWAA@1224|Proteobacteria,2TT6E@28211|Alphaproteobacteria,2K1BQ@204457|Sphingomonadales	204457|Sphingomonadales	E	protein involved in cysteine biosynthesis	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
WH3_k127_9327757_6	1479239.JQMU01000001_gene1482	5.194e-44	166.0	2EHHR@1|root,33B9P@2|Bacteria,1NGHW@1224|Proteobacteria,2UJVS@28211|Alphaproteobacteria,2K6SJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9327757_1	1479239.JQMU01000001_gene1481	1.277e-166	528.0	28N2A@1|root,2ZB84@2|Bacteria,1R8N1@1224|Proteobacteria,2U7C7@28211|Alphaproteobacteria,2K4F8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9327757_5	1248917.ANFX01000013_gene1502	1.078e-45	164.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria,2K4FF@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
WH3_k127_9340836_2	1248917.ANFX01000019_gene2335	6.936e-148	469.0	COG1028@1|root,COG1028@2|Bacteria,1NB6S@1224|Proteobacteria,2U1XH@28211|Alphaproteobacteria,2K20C@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_9340836_1	1479239.JQMU01000001_gene1577	3.441e-151	481.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2TSNX@28211|Alphaproteobacteria,2K9H3@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WH3_k127_9340836_0	1479239.JQMU01000001_gene1578	9.073e-273	842.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2TUZ7@28211|Alphaproteobacteria,2KD4G@204457|Sphingomonadales	204457|Sphingomonadales	C	FAD binding domain	-	-	1.3.99.4	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09884	RC00991	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
WH3_k127_9368761_6	1479239.JQMU01000001_gene2228	1.822e-28	114.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2K1S8@204457|Sphingomonadales	204457|Sphingomonadales	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
WH3_k127_9368761_0	1479239.JQMU01000001_gene2227	0.0	1471.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2K05M@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WH3_k127_9368761_4	1248917.ANFX01000012_gene1819	2.636e-54	192.0	2E6S2@1|root,331C5@2|Bacteria,1RH06@1224|Proteobacteria,2U98E@28211|Alphaproteobacteria,2K6C3@204457|Sphingomonadales	204457|Sphingomonadales	S	Signal peptide protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9368761_5	1479239.JQMU01000001_gene2225	5.769e-36	146.0	2EGQ7@1|root,33AGD@2|Bacteria,1NI1N@1224|Proteobacteria,2UJJ3@28211|Alphaproteobacteria,2K5B7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9368761_3	1479239.JQMU01000001_gene2224	1.109e-61	214.0	COG3187@1|root,COG3187@2|Bacteria,1Q8JA@1224|Proteobacteria,2UWID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
WH3_k127_9368761_2	1248917.ANFX01000012_gene1818	2e-323	995.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,2K0IY@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
WH3_k127_9368761_1	1248917.ANFX01000012_gene1817	0.0	1017.0	COG0591@1|root,COG4251@1|root,COG0591@2|Bacteria,COG4251@2|Bacteria,1QTSW@1224|Proteobacteria,2TW0C@28211|Alphaproteobacteria,2K0PA@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
WH3_k127_9447950_1	1122970.AUHC01000005_gene1935	1.84e-275	851.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,2K05C@204457|Sphingomonadales	204457|Sphingomonadales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
WH3_k127_9447950_7	383381.EH30_02395	2.651e-47	170.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2UBXS@28211|Alphaproteobacteria,2K5AR@204457|Sphingomonadales	204457|Sphingomonadales	C	nad(P) transhydrogenase subunit alpha	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
WH3_k127_9447950_6	1248917.ANFX01000038_gene588	3.553e-64	221.0	arCOG12631@1|root,3172B@2|Bacteria,1RH7M@1224|Proteobacteria,2UCDR@28211|Alphaproteobacteria,2K6DZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_1
WH3_k127_9447950_3	1219035.NT2_02_02020	9.058e-189	595.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,2K062@204457|Sphingomonadales	204457|Sphingomonadales	C	NAD(P) transhydrogenase subunit alpha	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WH3_k127_9447950_0	1479239.JQMU01000001_gene2414	1.688e-279	864.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0T8@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WH3_k127_9447950_5	1479239.JQMU01000001_gene2412	7.764e-124	403.0	COG4221@1|root,COG4221@2|Bacteria,1RAAB@1224|Proteobacteria,2U69E@28211|Alphaproteobacteria,2K0MR@204457|Sphingomonadales	204457|Sphingomonadales	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_9447950_8	573065.Astex_0886	2.703e-30	125.0	2DQSA@1|root,338DE@2|Bacteria,1N8HQ@1224|Proteobacteria,2UUVC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9447950_2	1479239.JQMU01000001_gene2411	4.506e-221	699.0	COG3540@1|root,COG3540@2|Bacteria,1R5RU@1224|Proteobacteria,2U4KZ@28211|Alphaproteobacteria,2K8XM@204457|Sphingomonadales	204457|Sphingomonadales	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
WH3_k127_9447950_4	1248917.ANFX01000038_gene582	4.569e-143	456.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,2K0EE@204457|Sphingomonadales	204457|Sphingomonadales	H	dihydropteroate synthase	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WH3_k127_94486_0	1479239.JQMU01000001_gene2297	5.178e-251	779.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,2K1GM@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WH3_k127_94486_1	1479239.JQMU01000001_gene2296	2.271e-216	673.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2K18Y@204457|Sphingomonadales	204457|Sphingomonadales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WH3_k127_94486_2	1248917.ANFX01000012_gene1885	3.657e-132	424.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,2K1N2@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WH3_k127_9450787_0	1248917.ANFX01000030_gene523	6.762e-197	618.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,2K00E@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
WH3_k127_9450787_1	1248917.ANFX01000030_gene522	3.598e-135	437.0	COG0657@1|root,COG0657@2|Bacteria,1RGPG@1224|Proteobacteria,2UA65@28211|Alphaproteobacteria,2K39A@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Abhydrolase_6
WH3_k127_9450787_2	1248917.ANFX01000030_gene521	1.1e-91	304.0	COG0657@1|root,COG0657@2|Bacteria,1RGPG@1224|Proteobacteria,2UA65@28211|Alphaproteobacteria,2K39A@204457|Sphingomonadales	204457|Sphingomonadales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Abhydrolase_6
WH3_k127_9455252_0	1479239.JQMU01000001_gene2545	1.823e-232	722.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,2TSF8@28211|Alphaproteobacteria,2K0KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WH3_k127_9455252_1	1044.EH31_09595	3.794e-100	346.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQQE@28211|Alphaproteobacteria,2K2U5@204457|Sphingomonadales	204457|Sphingomonadales	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
WH3_k127_9455252_2	1044.EH31_06925	9.947e-17	81.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2UBA1@28211|Alphaproteobacteria,2KDA3@204457|Sphingomonadales	204457|Sphingomonadales	NT	CheW-like domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WH3_k127_9461588_0	1248917.ANFX01000008_gene428	3.182e-165	522.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2TS31@28211|Alphaproteobacteria,2K1MM@204457|Sphingomonadales	204457|Sphingomonadales	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH3_k127_9461588_2	1248917.ANFX01000008_gene427	6.121e-38	143.0	28WVU@1|root,2ZIV5@2|Bacteria,1NGX2@1224|Proteobacteria,2UJJ9@28211|Alphaproteobacteria,2K6RU@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2842
WH3_k127_9461588_1	1248917.ANFX01000008_gene426	1.21e-97	324.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2UBY4@28211|Alphaproteobacteria,2K4TX@204457|Sphingomonadales	204457|Sphingomonadales	H	5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
WH3_k127_9465546_1	1248917.ANFX01000050_gene638	2.437e-145	473.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,2K0NQ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
WH3_k127_9465546_0	1479239.JQMU01000001_gene1047	4.502e-223	694.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WH3_k127_9473707_2	1248917.ANFX01000011_gene179	5.891e-118	382.0	COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2U0ZF@28211|Alphaproteobacteria,2K0DE@204457|Sphingomonadales	204457|Sphingomonadales	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WH3_k127_9473707_0	1479239.JQMU01000001_gene541	1.745e-134	432.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,2K33T@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_9473707_6	314225.ELI_07815	7.938e-49	186.0	COG3134@1|root,COG3134@2|Bacteria,1N5R8@1224|Proteobacteria,2UCFQ@28211|Alphaproteobacteria,2K6AP@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
WH3_k127_9473707_5	1479239.JQMU01000001_gene540	5.571e-65	226.0	COG3134@1|root,COG3134@2|Bacteria,1NAZ4@1224|Proteobacteria,2UHWJ@28211|Alphaproteobacteria,2K5Y8@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
WH3_k127_9473707_3	1248917.ANFX01000011_gene183	1.035e-107	352.0	COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,2U5IG@28211|Alphaproteobacteria,2K3XH@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
WH3_k127_9473707_4	1479239.JQMU01000001_gene538	1.294e-106	349.0	COG2227@1|root,COG2227@2|Bacteria,1QUNV@1224|Proteobacteria,2TW2B@28211|Alphaproteobacteria,2K5G3@204457|Sphingomonadales	204457|Sphingomonadales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
WH3_k127_9473707_1	1248917.ANFX01000011_gene185	5.265e-125	404.0	COG3904@1|root,COG3904@2|Bacteria,1R6HZ@1224|Proteobacteria,2U0MS@28211|Alphaproteobacteria,2K184@204457|Sphingomonadales	204457|Sphingomonadales	S	periplasmic protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9473707_7	1248917.ANFX01000011_gene186	1.639e-09	58.0	2C3YK@1|root,2ZHJ2@2|Bacteria,1RKGM@1224|Proteobacteria,2UBK5@28211|Alphaproteobacteria,2K5GJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_950320_3	1479239.JQMU01000001_gene2281	7.487e-17	80.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,2K5BJ@204457|Sphingomonadales	204457|Sphingomonadales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
WH3_k127_950320_0	1479239.JQMU01000001_gene2280	2.745e-116	379.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2TUSG@28211|Alphaproteobacteria,2K43Z@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
WH3_k127_950320_1	1479239.JQMU01000001_gene2279	1.857e-104	347.0	2BKNK@1|root,32F42@2|Bacteria,1NP5H@1224|Proteobacteria,2UXBZ@28211|Alphaproteobacteria,2K99J@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_950320_2	1479239.JQMU01000001_gene2277	7.647e-60	206.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,2K0AR@204457|Sphingomonadales	204457|Sphingomonadales	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WH3_k127_9546251_1	1122970.AUHC01000004_gene2206	8.035e-100	346.0	2AKVH@1|root,31BNP@2|Bacteria,1N2QY@1224|Proteobacteria,2UDTI@28211|Alphaproteobacteria,2K5N4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9546251_0	1479239.JQMU01000001_gene1970	1.476e-255	794.0	COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,2TS4P@28211|Alphaproteobacteria,2K0A7@204457|Sphingomonadales	204457|Sphingomonadales	M	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
WH3_k127_9546251_2	1122970.AUHC01000004_gene2204	2.948e-84	280.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2K4E9@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
WH3_k127_9546251_3	1122970.AUHC01000004_gene2203	1.337e-70	241.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,2U5D2@28211|Alphaproteobacteria,2K0TS@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
WH3_k127_9565017_2	1248917.ANFX01000024_gene1177	3.432e-48	173.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2K07V@204457|Sphingomonadales	204457|Sphingomonadales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WH3_k127_9565017_0	1479239.JQMU01000001_gene289	5.295e-115	376.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2TURT@28211|Alphaproteobacteria,2K2E9@204457|Sphingomonadales	204457|Sphingomonadales	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WH3_k127_9565017_1	1479239.JQMU01000001_gene290	3.381e-104	339.0	COG2200@1|root,COG2200@2|Bacteria,1R65R@1224|Proteobacteria,2U2PH@28211|Alphaproteobacteria,2K0M8@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WH3_k127_9575007_1	1248916.ANFY01000007_gene2548	2.07e-134	435.0	COG1018@1|root,COG3576@1|root,COG1018@2|Bacteria,COG3576@2|Bacteria,1MV41@1224|Proteobacteria,2TQXP@28211|Alphaproteobacteria,2K2UG@204457|Sphingomonadales	204457|Sphingomonadales	C	Oxidoreductase FAD-binding domain	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1,Putative_PNPOx
WH3_k127_9575007_2	697282.Mettu_1452	3.656e-134	435.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,1XE3V@135618|Methylococcales	1236|Gammaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
WH3_k127_9575007_5	1248916.ANFY01000007_gene2549	4.119e-98	325.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2U5BS@28211|Alphaproteobacteria,2K4S9@204457|Sphingomonadales	204457|Sphingomonadales	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WH3_k127_9575007_8	1230476.C207_06617	1.504e-77	265.0	COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2TUCA@28211|Alphaproteobacteria,3JQXA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	MA20_18655	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
WH3_k127_9575007_7	1265490.JHVY01000003_gene3153	6.712e-83	278.0	COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,1S252@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	50S ribosomal protein L21	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
WH3_k127_9575007_9	663278.Ethha_0126	5.268e-20	93.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJVA@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WH3_k127_9575007_6	1248916.ANFY01000007_gene2558	4.247e-90	299.0	2ANK7@1|root,31DJB@2|Bacteria,1R2CN@1224|Proteobacteria,2TZHE@28211|Alphaproteobacteria,2KETJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
WH3_k127_9575007_3	1537715.JQFJ01000002_gene718	6.713e-117	388.0	COG0793@1|root,COG0793@2|Bacteria,1R7I0@1224|Proteobacteria,2U0JI@28211|Alphaproteobacteria,2K40V@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41
WH3_k127_9575007_4	1479239.JQMU01000001_gene1624	6.237e-103	356.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2U1MH@28211|Alphaproteobacteria,2K0EG@204457|Sphingomonadales	204457|Sphingomonadales	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WH3_k127_9575007_0	1248917.ANFX01000040_gene774	1.601e-163	533.0	COG0006@1|root,COG0006@2|Bacteria,1MVHD@1224|Proteobacteria,2UCJB@28211|Alphaproteobacteria,2K0RC@204457|Sphingomonadales	204457|Sphingomonadales	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
WH3_k127_9611201_0	1248917.ANFX01000026_gene1041	1.144e-246	764.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,2K12N@204457|Sphingomonadales	204457|Sphingomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
WH3_k127_9611201_1	1479239.JQMU01000001_gene1342	9.384e-147	468.0	COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria,2K171@204457|Sphingomonadales	204457|Sphingomonadales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WH3_k127_9611201_2	1479239.JQMU01000001_gene1341	2.57e-125	406.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria,2K074@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
WH3_k127_9611201_3	517722.AEUE01000001_gene2428	9.785e-12	66.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TS80@28211|Alphaproteobacteria,2K087@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WH3_k127_9623670_1	1479239.JQMU01000001_gene314	2.073e-71	241.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,2K0R8@204457|Sphingomonadales	204457|Sphingomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WH3_k127_9623670_0	1479239.JQMU01000001_gene313	0.0	1339.0	COG5002@1|root,COG5002@2|Bacteria,1QUNI@1224|Proteobacteria,2TW1W@28211|Alphaproteobacteria,2KE90@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,PAS_8
WH3_k127_9723530_0	1479239.JQMU01000001_gene2713	2.653e-127	407.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2K1EY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WH3_k127_9723530_1	237727.NAP1_05370	7.11e-116	389.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,2K4IM@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH3_k127_9723530_2	1479239.JQMU01000001_gene2715	6.406e-10	59.0	COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2TU16@28211|Alphaproteobacteria,2K0ET@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3376)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3376,Patatin
WH3_k127_9725623_1	383381.EH30_15575	7.303e-71	240.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VFFP@28211|Alphaproteobacteria,2KDWM@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WH3_k127_9725623_0	1479239.JQMU01000001_gene1562	8.152e-154	488.0	COG3828@1|root,COG3828@2|Bacteria,1QWCA@1224|Proteobacteria,2U1GQ@28211|Alphaproteobacteria,2K19I@204457|Sphingomonadales	204457|Sphingomonadales	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
WH3_k127_9725623_2	1122970.AUHC01000011_gene2713	4.633e-65	224.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TQRA@28211|Alphaproteobacteria,2K01U@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_9750336_0	366602.Caul_2098	3.231e-44	165.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2TT8A@28211|Alphaproteobacteria,2KGVY@204458|Caulobacterales	204458|Caulobacterales	NU	Bacterial type II/III secretion system short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
WH3_k127_9750336_2	1245469.S58_60010	3.267e-21	104.0	COG3156@1|root,COG3156@2|Bacteria,1RJRE@1224|Proteobacteria	1224|Proteobacteria	U	general secretion pathway protein K	xpsK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
WH3_k127_9750336_1	1382303.JPOM01000001_gene1028	7.02e-22	99.0	COG3773@1|root,COG3773@2|Bacteria,1RE11@1224|Proteobacteria,2U89A@28211|Alphaproteobacteria,2KGIC@204458|Caulobacterales	204458|Caulobacterales	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
WH3_k127_9775745_1	1479239.JQMU01000001_gene1261	7.631e-191	599.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,2U0RR@28211|Alphaproteobacteria,2K0B9@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
WH3_k127_9775745_0	1248917.ANFX01000013_gene1582	3.363e-227	706.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2K04D@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WH3_k127_9786597_4	1122970.AUHC01000004_gene2145	8.896e-33	128.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2K18T@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WH3_k127_9786597_2	1479239.JQMU01000001_gene1912	1.34e-83	279.0	COG5317@1|root,COG5317@2|Bacteria,1N9DI@1224|Proteobacteria,2UFAD@28211|Alphaproteobacteria,2K6FU@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1465)	-	-	-	ko:K13592	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF1465
WH3_k127_9786597_5	1479239.JQMU01000001_gene1913	1.33e-27	113.0	COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria,2K6XC@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
WH3_k127_9786597_6	1248917.ANFX01000046_gene609	1.495e-16	81.0	COG5570@1|root,COG5570@2|Bacteria,1NGRE@1224|Proteobacteria,2UJAX@28211|Alphaproteobacteria,2K7RY@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
WH3_k127_9786597_0	1479239.JQMU01000001_gene1914	0.0	1397.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria,2K17Q@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
WH3_k127_9786597_1	1479239.JQMU01000001_gene1915	2.993e-103	346.0	COG1426@1|root,COG1426@2|Bacteria,1RGRW@1224|Proteobacteria,2U92Y@28211|Alphaproteobacteria,2KD3D@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
WH3_k127_9786597_3	1479239.JQMU01000001_gene1916	4.063e-47	176.0	COG1729@1|root,COG1729@2|Bacteria,1R8C4@1224|Proteobacteria,2VBNQ@28211|Alphaproteobacteria,2K0FK@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
WH3_k127_9825689_1	1248917.ANFX01000047_gene1614	4.527e-188	595.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,2K18R@204457|Sphingomonadales	204457|Sphingomonadales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WH3_k127_9825689_0	1248917.ANFX01000047_gene1615	1.915e-203	634.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,2K1J3@204457|Sphingomonadales	204457|Sphingomonadales	C	E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
WH3_k127_9895515_2	1479239.JQMU01000001_gene2257	1.379e-75	262.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria,2K231@204457|Sphingomonadales	204457|Sphingomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WH3_k127_9895515_0	1248917.ANFX01000012_gene1848	2.423e-146	467.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2TS1V@28211|Alphaproteobacteria,2K15W@204457|Sphingomonadales	204457|Sphingomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WH3_k127_9895515_1	1248917.ANFX01000012_gene1847	2.17e-102	334.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,2JZUV@204457|Sphingomonadales	204457|Sphingomonadales	G	beta-N-acetylhexosaminidase	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
WH3_k127_9922288_5	1479239.JQMU01000001_gene505	2.069e-75	259.0	2BPS1@1|root,32IJB@2|Bacteria,1PD6R@1224|Proteobacteria,2V6HD@28211|Alphaproteobacteria,2KAIN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9922288_3	1479239.JQMU01000001_gene506	9.681e-91	303.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,2K5WP@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WH3_k127_9922288_1	1479239.JQMU01000001_gene507	3.752e-273	845.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2TS9N@28211|Alphaproteobacteria,2K1P6@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2CSK_N,HATPase_c
WH3_k127_9922288_6	1122970.AUHC01000009_gene307	6.402e-39	148.0	29288@1|root,2ZPSV@2|Bacteria,1NJAG@1224|Proteobacteria,2UMCR@28211|Alphaproteobacteria,2K6S1@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
WH3_k127_9922288_2	1479239.JQMU01000001_gene510	5.036e-101	334.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,2K40S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
WH3_k127_9922288_0	1479239.JQMU01000001_gene511	0.0	1088.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,2K0QQ@204457|Sphingomonadales	204457|Sphingomonadales	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
WH3_k127_9922288_4	1479239.JQMU01000001_gene512	8.765e-84	280.0	COG0583@1|root,COG0583@2|Bacteria,1MXC9@1224|Proteobacteria,2TTTY@28211|Alphaproteobacteria,2K5KF@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9922288_7	1479239.JQMU01000001_gene513	1.787e-26	110.0	COG1396@1|root,COG1396@2|Bacteria,1RKW7@1224|Proteobacteria,2U9PU@28211|Alphaproteobacteria,2K2H6@204457|Sphingomonadales	204457|Sphingomonadales	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
WH3_k127_9931804_5	1248917.ANFX01000020_gene2245	6.238e-109	353.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,2K16A@204457|Sphingomonadales	204457|Sphingomonadales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WH3_k127_9931804_2	1248917.ANFX01000008_gene322	2.619e-221	693.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2K2R1@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
WH3_k127_9931804_4	1248917.ANFX01000020_gene2246	4.505e-113	371.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,2K3CE@204457|Sphingomonadales	204457|Sphingomonadales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WH3_k127_9931804_3	1479239.JQMU01000001_gene830	5.693e-162	511.0	COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2TRJ8@28211|Alphaproteobacteria,2K1AH@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
WH3_k127_9931804_1	1479239.JQMU01000001_gene831	1.255e-228	710.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TVBB@28211|Alphaproteobacteria,2K1G8@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_9931804_0	1479239.JQMU01000001_gene832	3.509e-246	760.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TUVB@28211|Alphaproteobacteria,2K0FU@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_9962052_4	1479239.JQMU01000001_gene2576	2.032e-134	428.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2TU0Q@28211|Alphaproteobacteria,2K0CD@204457|Sphingomonadales	204457|Sphingomonadales	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
WH3_k127_9962052_11	1479239.JQMU01000001_gene2575	2.86e-28	114.0	299DG@1|root,2ZWGB@2|Bacteria,1NIZB@1224|Proteobacteria,2UM6D@28211|Alphaproteobacteria,2K87V@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9962052_0	1479239.JQMU01000001_gene2574	5.295e-249	772.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2K0AI@204457|Sphingomonadales	204457|Sphingomonadales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WH3_k127_9962052_12	1037409.BJ6T_14340	5.811e-10	60.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WH3_k127_9962052_1	1248917.ANFX01000008_gene411	3.173e-170	535.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,2K0TX@204457|Sphingomonadales	204457|Sphingomonadales	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WH3_k127_9962052_9	1502850.FG91_00264	9.813e-50	180.0	COG1917@1|root,COG1917@2|Bacteria,1QUA5@1224|Proteobacteria,2UC97@28211|Alphaproteobacteria,2KBDK@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9962052_5	1479239.JQMU01000001_gene2571	1.047e-114	373.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,2K0HQ@204457|Sphingomonadales	204457|Sphingomonadales	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WH3_k127_9962052_10	1479239.JQMU01000001_gene2570	1.385e-49	181.0	2AM8Q@1|root,31C3I@2|Bacteria,1P8UH@1224|Proteobacteria,2UWY6@28211|Alphaproteobacteria,2KBCP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9962052_6	1479239.JQMU01000001_gene2569	1.173e-112	366.0	COG0352@1|root,COG0352@2|Bacteria,1MV42@1224|Proteobacteria,2TSSA@28211|Alphaproteobacteria,2K16H@204457|Sphingomonadales	204457|Sphingomonadales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
WH3_k127_9962052_3	1248917.ANFX01000008_gene418	3.701e-160	508.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TU2S@28211|Alphaproteobacteria,2K14P@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
WH3_k127_9962052_7	1479239.JQMU01000001_gene2567	2.293e-82	275.0	COG2050@1|root,COG2050@2|Bacteria,1N088@1224|Proteobacteria,2UEDK@28211|Alphaproteobacteria,2KA1M@204457|Sphingomonadales	204457|Sphingomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WH3_k127_9962052_8	1479239.JQMU01000001_gene2566	2.155e-66	231.0	2AAQE@1|root,3102J@2|Bacteria,1PN2N@1224|Proteobacteria,2V0NX@28211|Alphaproteobacteria,2KAKV@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
WH3_k127_9962052_2	1479239.JQMU01000001_gene2565	1.299e-168	531.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,2K0JN@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WH3_k127_9963833_4	1479239.JQMU01000001_gene1745	5.764e-219	681.0	COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,2TQW3@28211|Alphaproteobacteria,2K1J0@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
WH3_k127_9963833_18	1479239.JQMU01000001_gene1744	1.456e-67	234.0	COG0346@1|root,COG0346@2|Bacteria,1RGTU@1224|Proteobacteria,2U9R1@28211|Alphaproteobacteria,2K6I5@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH3_k127_9963833_2	1479239.JQMU01000001_gene1743	1.404e-240	745.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JZVG@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WH3_k127_9963833_21	1479239.JQMU01000001_gene1742	8.83e-58	205.0	2E3G3@1|root,32YEY@2|Bacteria,1N87D@1224|Proteobacteria,2UVNI@28211|Alphaproteobacteria,2K6XN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9963833_14	1122970.AUHC01000013_gene1001	6.56e-86	288.0	COG5436@1|root,COG5436@2|Bacteria,1N3Y4@1224|Proteobacteria,2UHPY@28211|Alphaproteobacteria,2K6IE@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1254
WH3_k127_9963833_13	1122970.AUHC01000013_gene1000	3.304e-92	306.0	COG5402@1|root,COG5402@2|Bacteria,1N26C@1224|Proteobacteria,2TT9K@28211|Alphaproteobacteria,2K4ZE@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
WH3_k127_9963833_19	1122970.AUHC01000013_gene999	1.663e-64	222.0	COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,2UAE3@28211|Alphaproteobacteria,2K689@204457|Sphingomonadales	204457|Sphingomonadales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WH3_k127_9963833_26	1248917.ANFX01000035_gene1925	6.597e-36	138.0	2DR05@1|root,339MI@2|Bacteria,1NHD4@1224|Proteobacteria,2VECG@28211|Alphaproteobacteria,2K7IC@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase inhibitor I78 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I78
WH3_k127_9963833_0	1479239.JQMU01000001_gene1737	6.734e-295	907.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,2K07D@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WH3_k127_9963833_22	1479239.JQMU01000001_gene1736	3.693e-53	188.0	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,2UC11@28211|Alphaproteobacteria,2K5WC@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
WH3_k127_9963833_25	1479239.JQMU01000001_gene1735	7.155e-41	153.0	COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,2K5Z1@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0335 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2312
WH3_k127_9963833_20	1479239.JQMU01000001_gene1734	4.795e-59	206.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,2UCR7@28211|Alphaproteobacteria,2K5MQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WH3_k127_9963833_12	1479239.JQMU01000001_gene1733	1.46e-100	334.0	COG1266@1|root,COG1266@2|Bacteria,1NN54@1224|Proteobacteria,2UUZE@28211|Alphaproteobacteria,2K77V@204457|Sphingomonadales	204457|Sphingomonadales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WH3_k127_9963833_11	1479239.JQMU01000001_gene1732	2.823e-140	448.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,2K0KW@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WH3_k127_9963833_23	279238.Saro_0420	6.834e-50	180.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2UAVD@28211|Alphaproteobacteria,2K6EC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9963833_16	1248917.ANFX01000035_gene1914	5.016e-77	259.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,2K4M7@204457|Sphingomonadales	204457|Sphingomonadales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WH3_k127_9963833_24	1122970.AUHC01000018_gene2658	3.06e-47	179.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,2K5XC@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
WH3_k127_9963833_7	1248917.ANFX01000028_gene2217	2.696e-175	563.0	COG3172@1|root,COG3172@2|Bacteria,1MUSI@1224|Proteobacteria,2UAKD@28211|Alphaproteobacteria,2K65Q@204457|Sphingomonadales	204457|Sphingomonadales	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
WH3_k127_9963833_6	1248917.ANFX01000028_gene2216	1.935e-178	563.0	COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,2TV4M@28211|Alphaproteobacteria,2K0H8@204457|Sphingomonadales	204457|Sphingomonadales	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WH3_k127_9963833_10	1479239.JQMU01000001_gene1858	3.106e-144	458.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,2K0DH@204457|Sphingomonadales	204457|Sphingomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
WH3_k127_9963833_1	1248917.ANFX01000028_gene2214	5.923e-252	781.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,2K044@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
WH3_k127_9963833_15	1479239.JQMU01000001_gene1856	5.696e-84	285.0	COG1396@1|root,COG1396@2|Bacteria,1NN2X@1224|Proteobacteria,2UF1A@28211|Alphaproteobacteria,2K6D4@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,PilZ
WH3_k127_9963833_9	1479239.JQMU01000001_gene1855	1.356e-148	477.0	COG2199@1|root,COG3706@2|Bacteria,1NVZM@1224|Proteobacteria,2USQQ@28211|Alphaproteobacteria,2K9Y0@204457|Sphingomonadales	204457|Sphingomonadales	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
WH3_k127_9963833_3	1479239.JQMU01000001_gene1854	9.432e-223	697.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2TVIF@28211|Alphaproteobacteria,2K0X5@204457|Sphingomonadales	204457|Sphingomonadales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
WH3_k127_9963833_5	1479239.JQMU01000001_gene1852	1.999e-200	626.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,2K0DQ@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO,ThiG
WH3_k127_9963833_8	1479239.JQMU01000001_gene1851	1.47e-171	540.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2TR4V@28211|Alphaproteobacteria,2K0F7@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,ACT_6,Formyl_trans_N
WH3_k127_9963833_17	1479239.JQMU01000001_gene1850	3.036e-74	252.0	COG0346@1|root,COG0346@2|Bacteria,1N4DA@1224|Proteobacteria,2UEPZ@28211|Alphaproteobacteria,2K534@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WH3_k127_9963833_28	1479239.JQMU01000001_gene1849	7.599e-13	68.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales	204457|Sphingomonadales	CG	Dehydrogenase	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
WH3_k127_9968632_3	1248917.ANFX01000026_gene1054	5.592e-90	299.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2K0J3@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
WH3_k127_9968632_0	1479239.JQMU01000001_gene1358	2.824e-177	558.0	COG0484@1|root,COG2214@1|root,COG0484@2|Bacteria,COG2214@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2K1JP@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	dnaJ_2	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
WH3_k127_9968632_2	1479239.JQMU01000001_gene1359	2.821e-126	409.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TTN5@28211|Alphaproteobacteria,2K0UY@204457|Sphingomonadales	204457|Sphingomonadales	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WH3_k127_9968632_1	1479239.JQMU01000001_gene1360	5.227e-142	452.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,2K0BH@204457|Sphingomonadales	204457|Sphingomonadales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WH3_k127_9989363_2	1479239.JQMU01000001_gene1717	8.531e-85	284.0	COG1261@1|root,COG1261@2|Bacteria,1N59V@1224|Proteobacteria,2UDGT@28211|Alphaproteobacteria,2K6A1@204457|Sphingomonadales	204457|Sphingomonadales	NO	Chaperone for flagella basal body P-ring formation	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
WH3_k127_9989363_3	1479239.JQMU01000001_gene1719	4.264e-40	151.0	2AMC4@1|root,31C79@2|Bacteria,1ND0V@1224|Proteobacteria,2UIH1@28211|Alphaproteobacteria,2K7KH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WH3_k127_9989363_1	1479239.JQMU01000001_gene1720	1.267e-140	453.0	COG0741@1|root,COG0741@2|Bacteria,1MUMA@1224|Proteobacteria,2TSA5@28211|Alphaproteobacteria,2K190@204457|Sphingomonadales	204457|Sphingomonadales	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WH3_k127_9989363_0	1479239.JQMU01000001_gene1721	1.245e-223	698.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2TQUR@28211|Alphaproteobacteria,2K2PH@204457|Sphingomonadales	204457|Sphingomonadales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
## 2670 queries scanned
## Total time (seconds): 5.5809619426727295
## Rate: 478.41 q/s