## Tue Dec 16 16:53:14 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WLSH1_bin.15.fa -m mmseqs --itype genome -o WLSH1_bin.15 --output_dir /data/result/bins/wyx/egg/WLSH1_bin.15 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WLSH1_k127_10023656_0	877415.JNJQ01000053_gene2575	6.434e-06	48.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,3VNVM@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
WLSH1_k127_10023656_1	1070319.CAGGBEG34_20026	0.000607	47.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,1K979@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH1_k127_10044175_1	797209.ZOD2009_05987	5.155e-07	55.0	COG3291@1|root,arCOG02540@1|root,arCOG04500@1|root,arCOG10954@1|root,arCOG02508@2157|Archaea,arCOG02540@2157|Archaea,arCOG04500@2157|Archaea,arCOG10954@2157|Archaea,2XWGB@28890|Euryarchaeota,23UX2@183963|Halobacteria	183963|Halobacteria	M	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_10044175_0	264462.Bd2875	3.237e-08	58.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_10044175_3	56110.Oscil6304_3724	0.0006	53.0	COG0689@1|root,COG2931@1|root,COG3391@1|root,COG5184@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,COG5184@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
WLSH1_k127_10044175_2	1123501.KB902284_gene2245	0.0001641	53.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,HemolysinCabind
WLSH1_k127_10050630_0	1487923.DP73_17815	8.692e-18	95.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,264FP@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	resE6	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WLSH1_k127_10050630_2	1304885.AUEY01000001_gene3148	2.927e-12	68.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42QPB@68525|delta/epsilon subdivisions,2WMP0@28221|Deltaproteobacteria,2MJM0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07664	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_10050630_3	926561.KB900617_gene1288	3.237e-10	61.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WBM8@53433|Halanaerobiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_10050630_1	469617.FUAG_01421	4.708e-13	69.0	COG0745@1|root,COG0745@2|Bacteria,37A83@32066|Fusobacteria	32066|Fusobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_10050630_4	309799.DICTH_1122	1.681e-05	48.0	COG0745@1|root,COG0745@2|Bacteria	309799.DICTH_1122|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_1005873_0	289376.THEYE_A0131	2.654e-37	145.0	COG0209@1|root,COG0209@2|Bacteria,3J0MG@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
WLSH1_k127_10076859_0	518766.Rmar_1109	2.345e-142	457.0	COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,1FIKT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WLSH1_k127_10097733_0	365044.Pnap_2828	6.031e-13	71.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,4ACE6@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WLSH1_k127_1014955_0	944547.ABLL_2785	6.744e-74	256.0	COG3287@1|root,COG3437@1|root,COG3287@2|Bacteria,COG3437@2|Bacteria,1QUN9@1224|Proteobacteria,42PHR@68525|delta/epsilon subdivisions,2YMDI@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HD,PAS_3,PAS_9,Response_reg
WLSH1_k127_10218627_5	1301100.HG529352_gene4261	6.98e-06	50.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,36FK8@31979|Clostridiaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WLSH1_k127_10218627_1	511051.CSE_08320	4.256e-16	80.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WLSH1_k127_10218627_2	1033806.HTIA_2295	1.231e-11	74.0	COG0500@1|root,arCOG04583@2157|Archaea,2XTVC@28890|Euryarchaeota,23ST5@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH1_k127_10218627_4	880073.Calab_0284	1.576e-06	51.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	HD_5,Rrf2
WLSH1_k127_10218627_6	243231.GSU2226	0.000392	44.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,43TV2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WLSH1_k127_10218627_0	478749.BRYFOR_07862	2.122e-17	86.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WLSH1_k127_10218627_3	585501.HMPREF6123_2610	1.022e-09	61.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,2PR2D@265975|Oribacterium	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WLSH1_k127_10289266_0	330214.NIDE2807	1.545e-39	153.0	COG0469@1|root,COG0469@2|Bacteria,3J0XM@40117|Nitrospirae	2|Bacteria	G	Belongs to the pyruvate kinase family	pykF	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WLSH1_k127_10322098_0	309801.trd_0965	2.068e-86	302.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,27XI1@189775|Thermomicrobia	189775|Thermomicrobia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WLSH1_k127_10322098_4	906968.Trebr_2276	2.584e-28	119.0	COG0200@1|root,COG0200@2|Bacteria,2J7ZW@203691|Spirochaetes	203691|Spirochaetes	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
WLSH1_k127_10322098_2	428126.CLOSPI_01586	3.804e-36	146.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,3VQ7N@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
WLSH1_k127_10322098_3	879243.Poras_0353	4.647e-32	128.0	COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,22Y3P@171551|Porphyromonadaceae	976|Bacteroidetes	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
WLSH1_k127_10322098_1	1283287.KB822575_gene140	5.368e-51	186.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4DNFZ@85009|Propionibacteriales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
WLSH1_k127_10324582_0	1313304.CALK_0261	6.875e-51	193.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WLSH1_k127_10330876_0	517418.Ctha_0161	1.46e-52	201.0	COG0069@1|root,COG1773@1|root,COG0069@2|Bacteria,COG1773@2|Bacteria,1FDGS@1090|Chlorobi	1090|Chlorobi	C	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rubredoxin
WLSH1_k127_10330876_3	457421.CBFG_05839	3.038e-14	74.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia	186801|Clostridia	C	CoA-transferase family III	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
WLSH1_k127_10330876_1	1347392.CCEZ01000007_gene1957	5.99e-48	180.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,36FMV@31979|Clostridiaceae	186801|Clostridia	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
WLSH1_k127_10330876_4	10042.XP_006980203.1	0.0002316	45.0	COG1804@1|root,KOG3957@2759|Eukaryota,38CWZ@33154|Opisthokonta,3BB7M@33208|Metazoa,3D0JC@33213|Bilateria,4838Z@7711|Chordata,48ZTZ@7742|Vertebrata,3JBNC@40674|Mammalia,35AGG@314146|Euarchontoglires,4Q38P@9989|Rodentia	33208|Metazoa	I	succinate-hydroxymethylglutarate CoA-transferase activity	SUGCT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008410,GO:0016740,GO:0016782,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0047369	2.8.3.13	ko:K18703	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
WLSH1_k127_10330876_2	748280.NH8B_4001	2.67e-29	121.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KRVU@206351|Neisseriales	206351|Neisseriales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
WLSH1_k127_10378701_0	1034807.FBFL15_0422	3.446e-46	170.0	COG0741@1|root,COG0741@2|Bacteria,4NH4W@976|Bacteroidetes,1HXX8@117743|Flavobacteriia,2NU2Q@237|Flavobacterium	976|Bacteroidetes	M	Murein transglycosylase	mltD_2	-	-	-	-	-	-	-	-	-	-	-	SLT
WLSH1_k127_10378701_1	642492.Clole_3156	0.0002214	49.0	COG1404@1|root,COG1404@2|Bacteria,1V1KF@1239|Firmicutes,24HIT@186801|Clostridia	186801|Clostridia	O	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,SLH
WLSH1_k127_10378701_2	796940.HMPREF9628_00842	0.0005214	50.0	COG4099@1|root,COG4886@1|root,COG5386@1|root,COG5520@1|root,COG4099@2|Bacteria,COG4886@2|Bacteria,COG5386@2|Bacteria,COG5520@2|Bacteria,1V266@1239|Firmicutes,24GXP@186801|Clostridia,25T8R@186804|Peptostreptococcaceae	186801|Clostridia	M	Leucine Rich Repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,DUF1533,LRR_8,NEAT,SLH
WLSH1_k127_10393863_1	935948.KE386495_gene1019	5.179e-46	169.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,42EQF@68295|Thermoanaerobacterales	186801|Clostridia	P	Heavy metal transport detoxification protein	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH1_k127_10393863_5	338966.Ppro_2900	7.438e-09	57.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,43T86@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH1_k127_10393863_2	159087.Daro_1051	1.58e-39	150.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KU93@206389|Rhodocyclales	206389|Rhodocyclales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH1_k127_10393863_0	857293.CAAU_0298	3.043e-51	186.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,36DJE@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH1_k127_10393863_6	445970.ALIPUT_01992	0.0003061	43.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,2FNJA@200643|Bacteroidia	976|Bacteroidetes	P	copper-exporting ATPase	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH1_k127_10393863_4	537971.HCCG_00844	3.767e-09	59.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2YNVV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	bacterioferritin comigratory protein	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH1_k127_10393863_3	224324.aq_495	8.18e-17	81.0	COG1225@1|root,COG1225@2|Bacteria,2G42T@200783|Aquificae	200783|Aquificae	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH1_k127_10453458_0	869209.Tresu_0461	2.077e-110	362.0	COG0013@1|root,COG0013@2|Bacteria,2J5G2@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WLSH1_k127_10453458_2	519441.Smon_0984	5.079e-15	76.0	COG0817@1|root,COG0817@2|Bacteria,37A4F@32066|Fusobacteria	32066|Fusobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WLSH1_k127_10453458_1	1378168.N510_02211	1.403e-18	89.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes	1239|Firmicutes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WLSH1_k127_10484740_0	316274.Haur_4820	0.0004135	46.0	COG0451@1|root,COG0451@2|Bacteria,2GBGX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WLSH1_k127_10537268_0	555779.Dthio_PD1645	1.155e-21	100.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2M9D6@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WLSH1_k127_10537268_2	1123059.KB823014_gene66	2.281e-06	53.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2TV76@28211|Alphaproteobacteria,43WGV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	U	COG1459 Type II secretory pathway, component PulF	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
WLSH1_k127_10537268_1	264732.Moth_1552	2.225e-13	72.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,42F7Z@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WLSH1_k127_10537515_0	272123.Anacy_2329	2.316e-26	117.0	COG4953@1|root,COG4953@2|Bacteria,1G428@1117|Cyanobacteria,1HJCE@1161|Nostocales	1117|Cyanobacteria	M	TIGRFAM Penicillin-binding protein 1C	pbpB	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
WLSH1_k127_10537515_1	401053.AciPR4_0705	7.431e-10	61.0	COG5009@1|root,COG5009@2|Bacteria,3Y31C@57723|Acidobacteria,2JHJY@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WLSH1_k127_10663259_0	1047013.AQSP01000118_gene1252	7.222e-79	276.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_10663259_2	1463926.JOCA01000008_gene2446	0.0002327	51.0	COG0433@1|root,COG0433@2|Bacteria,2H4H2@201174|Actinobacteria	201174|Actinobacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,TraG-D_C,TrwB_AAD_bind
WLSH1_k127_10663259_1	1304284.L21TH_1456	1.167e-07	60.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	ko:K06915,ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	DUF853,DUF87,PLDc_2
WLSH1_k127_1067080_1	1048834.TC41_3044	7.133e-63	217.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli,2783X@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH1_k127_1067080_0	296587.XP_002500081.1	2.949e-94	317.0	COG0480@1|root,KOG0465@2759|Eukaryota,37K55@33090|Viridiplantae,34GS5@3041|Chlorophyta	3041|Chlorophyta	J	catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH1_k127_106748_0	1124780.ANNU01000020_gene3319	2.15e-45	171.0	COG1074@1|root,COG1074@2|Bacteria,4NEX4@976|Bacteroidetes,47KES@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	addA	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,PDDEXK_1,UvrD-helicase,UvrD_C
WLSH1_k127_106748_1	1379698.RBG1_1C00001G1424	1.875e-10	64.0	COG1184@1|root,COG1184@2|Bacteria	2|Bacteria	J	translation initiation factor activity	-	-	-	ko:K03239,ko:K03680	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	IF-2B
WLSH1_k127_10741888_0	348780.NP_4910A	2.925e-22	103.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,23S93@183963|Halobacteria	183963|Halobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WLSH1_k127_10741888_2	694431.DESACE_02545	4.855e-17	86.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2M6A3@213113|Desulfurellales	28221|Deltaproteobacteria	H	HemN C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WLSH1_k127_10741888_3	204669.Acid345_2366	2.364e-08	56.0	COG0635@1|root,COG0635@2|Bacteria,3Y2ZB@57723|Acidobacteria,2JHUT@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WLSH1_k127_10741888_1	760142.Hipma_0902	1.257e-18	90.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2M6A3@213113|Desulfurellales	28221|Deltaproteobacteria	H	HemN C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WLSH1_k127_10748168_1	1296415.JACC01000008_gene2325	5.597e-22	108.0	COG0457@1|root,COG5000@1|root,COG0457@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	4HB_MCP_1,Cache_3-Cache_2,HAMP,MCPsignal,PAS,PAS_4,PAS_9,SpoIIE,dCache_1
WLSH1_k127_10748168_0	909663.KI867150_gene87	2.12e-59	220.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
WLSH1_k127_10771221_1	1122182.KB903823_gene1388	5.136e-31	130.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,2GJ8N@201174|Actinobacteria,4DBN5@85008|Micromonosporales	201174|Actinobacteria	EH	chorismate binding enzyme	phzE	-	2.6.1.86	ko:K13063	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	R08956	RC00010,RC02387	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind,GATase
WLSH1_k127_10771221_4	1121403.AUCV01000002_gene484	0.000307	45.0	COG0147@1|root,COG0512@1|root,COG0147@2|Bacteria,COG0512@2|Bacteria,1R3RU@1224|Proteobacteria	1224|Proteobacteria	EH	chorismate binding enzyme	ehpC	-	2.6.1.86	ko:K13063	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	R08956	RC00010,RC02387	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind,GATase
WLSH1_k127_10771221_3	1007103.AFHW01000035_gene1910	7.037e-07	50.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HAZP@91061|Bacilli,26QJW@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH1_k127_10771221_0	1033743.CAES01000045_gene134	4.049e-34	134.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26QA9@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter, ATP-binding protein	ygaD	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
WLSH1_k127_10771221_2	631454.N177_2277	4.895e-10	61.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,1JNBR@119043|Rhodobiaceae	28211|Alphaproteobacteria	V	ABC transporter transmembrane region	msbA	-	-	ko:K02021,ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH1_k127_10784614_2	357808.RoseRS_2870	0.0002559	44.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi,37651@32061|Chloroflexia	32061|Chloroflexia	S	Alpha-2-macroglobulin family	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5
WLSH1_k127_10784614_0	1047013.AQSP01000123_gene1545	4.94e-45	186.0	COG2373@1|root,COG2373@2|Bacteria,2NQA2@2323|unclassified Bacteria	2|Bacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
WLSH1_k127_10784614_1	244582.JQAK01000001_gene943	7.76e-20	96.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
WLSH1_k127_10805302_2	697281.Mahau_0700	1.893e-42	158.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,42HQP@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
WLSH1_k127_10805302_1	1176165.CAJD01000011_gene599	8.077e-47	173.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4F9XE@85019|Brevibacteriaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
WLSH1_k127_10805302_0	796940.HMPREF9628_01890	6.93e-88	300.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,25QU2@186804|Peptostreptococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WLSH1_k127_1081435_6	883169.HMPREF9719_01504	0.0002582	46.0	COG4243@1|root,COG4243@2|Bacteria,2GMVK@201174|Actinobacteria,22NC6@1653|Corynebacteriaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
WLSH1_k127_1081435_4	1278073.MYSTI_05691	6.725e-17	89.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WLSH1_k127_1081435_2	556268.OFAG_01300	2.277e-35	135.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,4739J@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1,3.1.11.6	ko:K03601,ko:K04564	ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Sod_Fe_C,Sod_Fe_N
WLSH1_k127_1081435_1	557598.LHK_01716	5.041e-41	153.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,2KPPV@206351|Neisseriales	206351|Neisseriales	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WLSH1_k127_1081435_3	406817.XNC1_2690	3.522e-17	83.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WLSH1_k127_1081435_0	646529.Desaci_0542	3.284e-56	209.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,260QE@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH1_k127_1081435_5	1408422.JHYF01000012_gene3149	1.147e-05	49.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,36DVH@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH1_k127_10821306_0	1463841.JOIR01000004_gene6340	0.0005003	45.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria	201174|Actinobacteria	NU	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
WLSH1_k127_1087224_0	1128421.JAGA01000002_gene455	2.386e-64	234.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WLSH1_k127_1087224_1	435842.HMPREF0848_00751	2.376e-14	77.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes	1239|Firmicutes	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WLSH1_k127_10883283_1	1123376.AUIU01000016_gene218	2.312e-48	188.0	COG1459@1|root,COG1459@2|Bacteria,3J0HZ@40117|Nitrospirae	40117|Nitrospirae	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
WLSH1_k127_10883283_0	511051.CSE_14730	7.381e-90	309.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02652,ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH1_k127_10883283_2	153721.MYP_2706	6.99e-14	71.0	COG0796@1|root,COG0796@2|Bacteria,4NG1C@976|Bacteroidetes,47MMI@768503|Cytophagia	976|Bacteroidetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WLSH1_k127_10997949_0	649747.HMPREF0083_05957	5.712e-132	428.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,26R74@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WLSH1_k127_10997949_2	1235835.C814_03224	3.673e-09	57.0	COG0514@1|root,COG0551@1|root,COG0514@2|Bacteria,COG0551@2|Bacteria,1V63N@1239|Firmicutes,24A9F@186801|Clostridia,3WJKK@541000|Ruminococcaceae	186801|Clostridia	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	HRDC,NERD
WLSH1_k127_10997949_1	649764.HMPREF0762_00550	5.584e-57	201.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CUVC@84998|Coriobacteriia	84998|Coriobacteriia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WLSH1_k127_11018064_0	765420.OSCT_0738	3.055e-55	203.0	COG0847@1|root,COG1199@1|root,COG0847@2|Bacteria,COG1199@2|Bacteria,2G5P4@200795|Chloroflexi,374UA@32061|Chloroflexia	32061|Chloroflexia	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD_2,Helicase_C_2,RNase_T
WLSH1_k127_1133532_0	1444711.CCJF01000004_gene2092	1.949e-119	406.0	COG0060@1|root,COG0060@2|Bacteria,2JFQJ@204428|Chlamydiae	204428|Chlamydiae	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WLSH1_k127_1137411_1	675815.VOA_000948	6.591e-06	53.0	COG1802@1|root,COG1802@2|Bacteria,1QV8Z@1224|Proteobacteria,1T2AF@1236|Gammaproteobacteria,1XYCZ@135623|Vibrionales	135623|Vibrionales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36
WLSH1_k127_1137411_0	118005.AWNK01000003_gene2444	7.947e-14	81.0	COG1484@1|root,COG1484@2|Bacteria	2|Bacteria	L	DNA-dependent DNA replication	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
WLSH1_k127_1224605_1	401053.AciPR4_3032	3.67e-16	78.0	COG0443@1|root,COG0443@2|Bacteria,3Y2XU@57723|Acidobacteria,2JHT1@204432|Acidobacteriia	204432|Acidobacteriia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WLSH1_k127_1224605_0	412419.BDU_63	9.498e-27	116.0	COG1253@1|root,COG1253@2|Bacteria,2J61P@203691|Spirochaetes	203691|Spirochaetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
WLSH1_k127_1247476_0	227086.JGI_V11_80363	7.774e-05	45.0	KOG0589@1|root,KOG0589@2759|Eukaryota	2759|Eukaryota	T	protein serine/threonine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Kinase-like,Pkinase
WLSH1_k127_1256075_1	1158338.JNLJ01000001_gene557	1.391e-47	173.0	COG0468@1|root,COG0468@2|Bacteria,2G3UK@200783|Aquificae	200783|Aquificae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WLSH1_k127_1256075_0	1331060.RLDS_15010	4.668e-77	260.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2K1TR@204457|Sphingomonadales	204457|Sphingomonadales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WLSH1_k127_1284706_0	990073.ATHU01000001_gene684	2.7e-30	126.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2YMD5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WLSH1_k127_1293867_3	1173024.KI912151_gene1817	1.821e-05	46.0	COG0221@1|root,COG0221@2|Bacteria,1GKG1@1117|Cyanobacteria,1JM4R@1189|Stigonemataceae	1117|Cyanobacteria	C	Inorganic pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Pyrophosphatase
WLSH1_k127_1293867_1	1173024.KI912151_gene1817	3.25e-13	70.0	COG0221@1|root,COG0221@2|Bacteria,1GKG1@1117|Cyanobacteria,1JM4R@1189|Stigonemataceae	1117|Cyanobacteria	C	Inorganic pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Pyrophosphatase
WLSH1_k127_1293867_0	697284.ERIC2_c09060	1.592e-49	182.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,26R39@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH1_k127_1293867_2	857293.CAAU_0743	3.388e-07	51.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,36F1A@31979|Clostridiaceae	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH1_k127_1309639_0	102232.GLO73106DRAFT_00024430	2.594e-08	57.0	COG0597@1|root,COG0597@2|Bacteria,1G6MU@1117|Cyanobacteria	1117|Cyanobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WLSH1_k127_1309639_1	1437605.BACT_0449	1.591e-05	47.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CYYR@85004|Bifidobacteriales	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH1_k127_1378577_0	742723.HMPREF9477_01578	2.029e-39	154.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,27IR1@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WLSH1_k127_1378652_1	945713.IALB_0349	3.264e-12	72.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	AbfB,DUF2804,DUF4981,Glyco_hydro_106,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WLSH1_k127_1378652_0	945713.IALB_0348	3.365e-107	351.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	smc	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03529,ko:K19171	-	-	-	-	ko00000,ko02048,ko03036	-	-	-	SMC_N,SMC_hinge
WLSH1_k127_1407169_0	1089553.Tph_c04900	2.066e-06	54.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia,42FJ8@68295|Thermoanaerobacterales	186801|Clostridia	L	Flagellar Assembly Protein A	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA,Jag_N
WLSH1_k127_1425925_1	1069080.KB913028_gene272	1.259e-18	85.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes	909932|Negativicutes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WLSH1_k127_1425925_0	273068.TTE2774	3.826e-82	284.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,42FJ3@68295|Thermoanaerobacterales	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WLSH1_k127_1437362_0	283942.IL2216	1.003e-12	72.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,2QFPE@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
WLSH1_k127_1437362_1	1196083.SALWKB12_1840	3.487e-08	59.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,2VQBX@28216|Betaproteobacteria,2KQXN@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WLSH1_k127_1437362_2	1123278.KB893605_gene1751	0.0006968	44.0	COG0775@1|root,COG0775@2|Bacteria,4NMPF@976|Bacteroidetes,47K2M@768503|Cytophagia	976|Bacteroidetes	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WLSH1_k127_1446590_4	642492.Clole_3501	1.025e-05	51.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia	186801|Clostridia	M	Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
WLSH1_k127_1446590_3	36875.HQ29_04765	2.664e-11	64.0	COG0324@1|root,COG0324@2|Bacteria,4NEAE@976|Bacteroidetes,2FNES@200643|Bacteroidia,22WDD@171551|Porphyromonadaceae	976|Bacteroidetes	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH1_k127_1446590_2	243274.THEMA_02050	4.717e-15	78.0	COG0324@1|root,COG0324@2|Bacteria,2GCE7@200918|Thermotogae	200918|Thermotogae	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH1_k127_1446590_1	1121947.AUHK01000001_gene730	6.875e-17	82.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,22G41@1570339|Peptoniphilaceae	186801|Clostridia	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH1_k127_1446590_0	742738.HMPREF9460_02189	6.098e-17	83.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,267JZ@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH1_k127_1465986_0	1382356.JQMP01000004_gene471	1.394e-56	210.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia	189775|Thermomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
WLSH1_k127_1472378_1	1123284.KB899046_gene2284	6.735e-09	63.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HA6Y@91061|Bacilli	91061|Bacilli	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WLSH1_k127_1472378_0	1242864.D187_007278	1.531e-28	121.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria,2YV2N@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE,MFS_1
WLSH1_k127_1472378_2	1122927.KB895413_gene1842	0.000402	53.0	COG3976@1|root,COG3976@2|Bacteria,1VBTI@1239|Firmicutes,4HKRR@91061|Bacilli,26YWR@186822|Paenibacillaceae	91061|Bacilli	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
WLSH1_k127_1493314_0	1158318.ATXC01000001_gene529	4.773e-14	76.0	COG0771@1|root,COG0771@2|Bacteria,2G3XE@200783|Aquificae	200783|Aquificae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH1_k127_1493314_2	547144.HydHO_1485	7.015e-06	52.0	COG0771@1|root,COG0771@2|Bacteria,2G3XE@200783|Aquificae	200783|Aquificae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH1_k127_1493314_1	224324.aq_2075	7.761e-10	65.0	COG0771@1|root,COG0771@2|Bacteria,2G3XE@200783|Aquificae	200783|Aquificae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH1_k127_1535378_2	402612.FP0151	8.735e-23	102.0	COG3963@1|root,COG3963@2|Bacteria,4NPMV@976|Bacteroidetes,1I1YR@117743|Flavobacteriia	976|Bacteroidetes	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_12,Methyltransf_25,RrnaAD
WLSH1_k127_1535378_3	1262449.CP6013_3882	0.0009645	43.0	COG3963@1|root,COG3963@2|Bacteria,1V2ZK@1239|Firmicutes,24IUQ@186801|Clostridia,36HY6@31979|Clostridiaceae	186801|Clostridia	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	RrnaAD
WLSH1_k127_1535378_1	1254432.SCE1572_03990	1.038e-54	200.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2YV5P@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH1_k127_1535378_0	888727.HMPREF9092_1403	1.137e-65	229.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3WCIN@538999|Clostridiales incertae sedis	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH1_k127_1536536_5	679926.Mpet_2754	3.034e-05	49.0	COG2304@1|root,arCOG02902@2157|Archaea,2XVVH@28890|Euryarchaeota,2NADG@224756|Methanomicrobia	224756|Methanomicrobia	S	Aerotolerance regulator N-terminal	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
WLSH1_k127_1536536_2	626522.GCWU000325_00301	1.059e-28	122.0	COG1721@1|root,COG1721@2|Bacteria,4NE2N@976|Bacteroidetes,2FNSY@200643|Bacteroidia,1WD7E@1283313|Alloprevotella	976|Bacteroidetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WLSH1_k127_1536536_0	742823.HMPREF9465_00785	2.195e-40	157.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,4PQJC@995019|Sutterellaceae	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WLSH1_k127_1536536_3	795359.TOPB45_0844	8.594e-19	89.0	COG0766@1|root,COG0766@2|Bacteria,2GHFF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WLSH1_k127_1536536_4	1384484.AEQU_1319	1.863e-18	87.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4CUMS@84998|Coriobacteriia	84998|Coriobacteriia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WLSH1_k127_1536536_1	1121267.JHZL01000007_gene754	4.955e-35	140.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2YNWA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0321	Guanylate_kin
WLSH1_k127_1605891_0	411483.FAEPRAA2165_01603	5.576e-76	260.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WGA4@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH1_k127_1605891_1	471875.RUMLAC_00081	2.344e-22	101.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3WGA4@541000|Ruminococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH1_k127_1684902_0	935836.JAEL01000122_gene2004	1.577e-55	206.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,1ZCM9@1386|Bacillus	91061|Bacilli	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH1_k127_1716676_1	1265502.KB905930_gene1550	7.85e-29	120.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,4ADXV@80864|Comamonadaceae	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WLSH1_k127_1716676_2	1410638.JHXJ01000008_gene416	1.623e-19	91.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WLSH1_k127_1716676_3	1227349.C170_16185	1.059e-12	76.0	COG0671@1|root,COG0671@2|Bacteria,1VARM@1239|Firmicutes,4HIM1@91061|Bacilli,26ZB1@186822|Paenibacillaceae	91061|Bacilli	I	bacitracin transport permease	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2,PAP2_3
WLSH1_k127_1716676_0	1122603.ATVI01000007_gene1543	1.263e-53	195.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,1SZ3S@1236|Gammaproteobacteria,1X7S5@135614|Xanthomonadales	135614|Xanthomonadales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH1_k127_1726715_0	574087.Acear_1202	0.0003135	50.0	COG1075@1|root,COG1075@2|Bacteria,1VJP5@1239|Firmicutes,250IX@186801|Clostridia,3WBMR@53433|Halanaerobiales	186801|Clostridia	S	Putative serine esterase (DUF676)	-	-	-	-	-	-	-	-	-	-	-	-	DUF676
WLSH1_k127_1777473_0	1321778.HMPREF1982_01904	3.004e-70	246.0	COG1814@1|root,COG1814@2|Bacteria,1V4D2@1239|Firmicutes	1239|Firmicutes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WLSH1_k127_1780985_0	502025.Hoch_1025	4.143e-23	111.0	COG0358@1|root,COG1793@1|root,COG0358@2|Bacteria,COG1793@2|Bacteria,1REUN@1224|Proteobacteria,430W6@68525|delta/epsilon subdivisions,2WW2U@28221|Deltaproteobacteria,2YZHZ@29|Myxococcales	28221|Deltaproteobacteria	L	DNA primase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_1780985_2	926554.KI912657_gene4298	2.568e-05	49.0	2EUAB@1|root,33MSR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_1796646_0	1293054.HSACCH_00630	9.809e-155	509.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WA6Y@53433|Halanaerobiales	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WLSH1_k127_182151_0	393595.ABO_2523	0.0001356	48.0	COG0845@1|root,COG0845@2|Bacteria,1R866@1224|Proteobacteria,1SYE2@1236|Gammaproteobacteria,1XR97@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18302	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2,8.A.1	-	-	HlyD_D23
WLSH1_k127_182151_1	439235.Dalk_2024	0.0005209	50.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MJGT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
WLSH1_k127_1829863_0	264199.stu1801	1.113e-52	196.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli	91061|Bacilli	L	Hydrolase, tatd	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WLSH1_k127_1829863_4	1227272.HMPREF1556_00486	1.08e-12	71.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,2FNPV@200643|Bacteroidia,22XSI@171551|Porphyromonadaceae	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WLSH1_k127_1829863_5	391600.ABRU01000040_gene1730	2.332e-09	61.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2TRJR@28211|Alphaproteobacteria,2KGCG@204458|Caulobacterales	204458|Caulobacterales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WLSH1_k127_1829863_3	693986.MOC_4425	9.285e-13	72.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,1JQUB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
WLSH1_k127_1829863_1	748449.Halha_0897	1.64e-26	113.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WAKV@53433|Halanaerobiales	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WLSH1_k127_1829863_2	555088.DealDRAFT_0481	2.184e-23	102.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,42JVD@68298|Syntrophomonadaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WLSH1_k127_1832878_2	1500306.JQLA01000002_gene1356	1.534e-05	56.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,4B9A1@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC-type oligopeptide transport system, periplasmic component	nikA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH1_k127_1832878_0	926550.CLDAP_12320	1.156e-12	71.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WLSH1_k127_1832878_1	909663.KI867150_gene4	2.536e-08	60.0	COG3462@1|root,COG3462@2|Bacteria,1Q55M@1224|Proteobacteria,42WZ8@68525|delta/epsilon subdivisions,2WSP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
WLSH1_k127_189385_0	330214.NIDE3856	4.662e-05	53.0	COG3541@1|root,COG3541@2|Bacteria	2|Bacteria	L	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
WLSH1_k127_1908032_1	945713.IALB_2993	6.371e-12	69.0	2C97T@1|root,338QQ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
WLSH1_k127_1908032_0	1128912.GMES_2010	9.104e-71	250.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,4670H@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
WLSH1_k127_1938818_0	221288.JH992901_gene5682	4.492e-14	78.0	COG0586@1|root,COG0586@2|Bacteria,1G184@1117|Cyanobacteria,1JJT8@1189|Stigonemataceae	1117|Cyanobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
WLSH1_k127_1943738_0	945713.IALB_1378	1.12e-167	533.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WLSH1_k127_2022575_0	357808.RoseRS_2190	2.176e-11	75.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WLSH1_k127_203482_0	509191.AEDB02000109_gene4999	6.541e-67	233.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,3WGU2@541000|Ruminococcaceae	186801|Clostridia	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH1_k127_203482_2	639282.DEFDS_0625	9.616e-10	64.0	COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH1_k127_203482_1	522772.Dacet_2370	3.016e-10	65.0	COG0718@1|root,COG0718@2|Bacteria,2GFU9@200930|Deferribacteres	200930|Deferribacteres	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
WLSH1_k127_2042016_0	111780.Sta7437_0383	7.238e-29	127.0	COG1559@1|root,COG1559@2|Bacteria,1G27J@1117|Cyanobacteria,3VJCI@52604|Pleurocapsales	1117|Cyanobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WLSH1_k127_2057645_1	69014.TK0888	5.396e-12	69.0	COG2002@1|root,arCOG00812@2157|Archaea,2Y6IB@28890|Euryarchaeota,244N0@183968|Thermococci	183968|Thermococci	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
WLSH1_k127_2057645_0	1121428.DESHY_30138___1	6.045e-20	94.0	COG1569@1|root,COG1569@2|Bacteria,1VHAV@1239|Firmicutes,24QPU@186801|Clostridia,2671I@186807|Peptococcaceae	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WLSH1_k127_2122375_1	373903.Hore_05820	2.555e-37	150.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,3WAJ2@53433|Halanaerobiales	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WLSH1_k127_2122375_0	1123376.AUIU01000011_gene1073	7.46e-50	184.0	COG1494@1|root,COG1494@2|Bacteria	2|Bacteria	G	fructose-1,6-bisphosphatase	glpX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11,3.1.3.37	ko:K02446,ko:K11532	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
WLSH1_k127_2181646_0	1191523.MROS_2541	3.263e-42	158.0	COG1493@1|root,COG1493@2|Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
WLSH1_k127_2181646_2	717231.Flexsi_0985	9.094e-09	61.0	COG1544@1|root,COG1544@2|Bacteria,2GFDP@200930|Deferribacteres	200930|Deferribacteres	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
WLSH1_k127_2181646_1	888059.HMPREF9071_1366	3.872e-32	128.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,1HWMN@117743|Flavobacteriia,1EQ7K@1016|Capnocytophaga	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WLSH1_k127_2189396_0	525904.Tter_0997	7.131e-69	243.0	COG0391@1|root,COG0391@2|Bacteria,2NP7Q@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0052	ybhK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
WLSH1_k127_2189396_1	1501230.ET33_15665	8.652e-10	61.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,26RR1@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
WLSH1_k127_220562_0	932678.THERU_03350	1.156e-41	161.0	COG1692@1|root,COG1692@2|Bacteria,2G3Y9@200783|Aquificae	200783|Aquificae	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
WLSH1_k127_220562_1	375451.RD1_2012	3.725e-08	57.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,2TS4S@28211|Alphaproteobacteria,2P10C@2433|Roseobacter	28211|Alphaproteobacteria	S	protein conserved in bacteria	MA20_17970	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
WLSH1_k127_2236186_0	563040.Saut_0889	1.846e-23	104.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WLSH1_k127_2236186_2	1195236.CTER_0195	0.0006574	46.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,3WHII@541000|Ruminococcaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH1_k127_2236186_1	1183438.GKIL_1805	1.075e-06	57.0	COG0845@1|root,COG0845@2|Bacteria,1G0KI@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH1_k127_2254234_1	439235.Dalk_4811	1.182e-27	122.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2MI9W@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
WLSH1_k127_2254234_0	1128421.JAGA01000002_gene1247	4.527e-35	141.0	COG0744@1|root,COG0744@2|Bacteria	2|Bacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
WLSH1_k127_2323372_0	485918.Cpin_5506	1.279e-71	253.0	COG2755@1|root,COG5434@1|root,COG2755@2|Bacteria,COG5434@2|Bacteria,4NG4T@976|Bacteroidetes,1IPJZ@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM glycoside hydrolase family 28	-	-	-	ko:K19172	-	-	-	-	ko00000,ko02048	-	-	-	Glyco_hydro_28,Lipase_GDSL_2,Pectate_lyase_3
WLSH1_k127_2323372_1	411476.BACOVA_04901	1.816e-66	230.0	COG4677@1|root,COG4677@2|Bacteria,4NEEI@976|Bacteroidetes,2FMFM@200643|Bacteroidia,4AVS3@815|Bacteroidaceae	976|Bacteroidetes	M	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Pectinesterase
WLSH1_k127_239230_1	313612.L8106_04089	4.548e-21	102.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
WLSH1_k127_239230_2	179408.Osc7112_1554	3.049e-13	72.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,dCache_1
WLSH1_k127_239230_0	700598.Niako_5466	1.003e-67	237.0	COG0313@1|root,COG0313@2|Bacteria,4NFQM@976|Bacteroidetes,1IPC1@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WLSH1_k127_2399894_0	857087.Metme_1830	2.18e-120	410.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,1XGNR@135618|Methylococcales	135618|Methylococcales	P	PFAM Cation H exchanger	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
WLSH1_k127_2409290_2	1123371.ATXH01000012_gene1434	5.642e-14	75.0	COG0254@1|root,COG0254@2|Bacteria,2GI27@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WLSH1_k127_2409290_0	1173029.JH980292_gene3582	7.359e-28	124.0	COG2208@1|root,COG4191@1|root,COG2208@2|Bacteria,COG4191@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
WLSH1_k127_2409290_1	1449355.JQNR01000005_gene4402	6.501e-15	83.0	COG3451@1|root,COG3451@2|Bacteria,2GM5W@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory pathway, VirB4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
WLSH1_k127_2409290_3	478749.BRYFOR_08977	4.824e-08	56.0	COG3451@1|root,COG3451@2|Bacteria,1TQGE@1239|Firmicutes,24ACY@186801|Clostridia	186801|Clostridia	U	COG COG3451 Type IV secretory pathway, VirB4 components	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
WLSH1_k127_2437392_4	1235790.C805_00436	1.269e-08	56.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,25VU6@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WLSH1_k127_2437392_3	1450694.BTS2_1892	1.063e-12	71.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,1ZBZD@1386|Bacillus	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WLSH1_k127_2437392_7	1380355.JNIJ01000014_gene569	0.0003627	47.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,3JUZI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WLSH1_k127_2437392_6	289376.THEYE_A0984	2.007e-07	55.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	PFOR_II,POR,POR_N,Transketolase_C
WLSH1_k127_2437392_0	485913.Krac_6794	5.615e-27	114.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WLSH1_k127_2437392_5	1265505.ATUG01000001_gene3143	8.851e-08	56.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2MI7V@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH1_k127_2437392_8	456442.Mboo_0730	0.0003888	47.0	COG0674@1|root,arCOG01607@2157|Archaea,2Y7K5@28890|Euryarchaeota,2N9RY@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH1_k127_2437392_1	273075.Ta0772m	9.63e-25	106.0	COG1013@1|root,arCOG01599@2157|Archaea,2XUA1@28890|Euryarchaeota,241UV@183967|Thermoplasmata	183967|Thermoplasmata	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
WLSH1_k127_2437392_2	1157490.EL26_07490	1.528e-22	99.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,4HAA4@91061|Bacilli	91061|Bacilli	C	Catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	PFO_beta_C,TPP_enzyme_C
WLSH1_k127_2528068_0	1121481.AUAS01000002_gene3235	1.026e-38	149.0	COG1846@1|root,COG1846@2|Bacteria,4NT8S@976|Bacteroidetes	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WLSH1_k127_2562403_0	449447.MAE_05630	4.89e-31	134.0	COG0342@1|root,COG0342@2|Bacteria,1G053@1117|Cyanobacteria	1117|Cyanobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH1_k127_2562403_1	582515.KR51_00026430	2.357e-05	53.0	COG0342@1|root,COG0342@2|Bacteria,1G053@1117|Cyanobacteria	1117|Cyanobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH1_k127_2577244_0	177437.HRM2_33680	3.885e-16	88.0	28M0D@1|root,2ZAFE@2|Bacteria,1R6YH@1224|Proteobacteria,42NPF@68525|delta/epsilon subdivisions,2WM7K@28221|Deltaproteobacteria,2MIG7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
WLSH1_k127_2580117_1	224324.aq_797	2.104e-41	158.0	COG0793@1|root,COG0793@2|Bacteria,2G3RT@200783|Aquificae	200783|Aquificae	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WLSH1_k127_2580117_4	1121472.AQWN01000004_gene773	0.0001124	47.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,262H5@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM desulfoferrodoxin FeS4 iron-binding domain	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
WLSH1_k127_2580117_3	1235797.C816_02231	6.677e-07	52.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N71Y@216572|Oscillospiraceae	186801|Clostridia	I	Rubredoxin	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin
WLSH1_k127_2580117_0	656519.Halsa_1274	3.33e-71	248.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WA6B@53433|Halanaerobiales	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WLSH1_k127_2580117_2	744872.Spica_2759	6.946e-37	141.0	COG1418@1|root,COG1418@2|Bacteria,2J5IM@203691|Spirochaetes	203691|Spirochaetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WLSH1_k127_2580117_5	439235.Dalk_1768	0.0003029	50.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH1_k127_2587639_0	526222.Desal_0033	5.09e-40	152.0	COG0450@1|root,COG0450@2|Bacteria,1MYZG@1224|Proteobacteria,42SNG@68525|delta/epsilon subdivisions,2WP3M@28221|Deltaproteobacteria,2M9GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
WLSH1_k127_2608710_0	592031.GCWU000322_00678	0.0001814	51.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,25V2U@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH1_k127_2617832_1	1009370.ALO_20932	4.217e-22	105.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H1WR@909932|Negativicutes	909932|Negativicutes	M	PFAM penicillin-binding protein transpeptidase, Penicillin-binding protein dimerization domain-containing protein, PASTA domain containing protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
WLSH1_k127_2617832_0	935948.KE386493_gene2325	1.621e-25	109.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,42FD0@68295|Thermoanaerobacterales	186801|Clostridia	M	TIGRFAM stage V sporulation protein D	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
WLSH1_k127_2617832_3	1319815.HMPREF0202_01881	8.966e-10	61.0	COG0768@1|root,COG0768@2|Bacteria,37861@32066|Fusobacteria	32066|Fusobacteria	M	Penicillin-binding protein, transpeptidase domain protein	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
WLSH1_k127_2617832_2	944480.ATUV01000001_gene1352	1.414e-13	73.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,2M6KW@213113|Desulfurellales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
WLSH1_k127_2620214_0	643562.Daes_2072	2.025e-85	299.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2M8QJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WLSH1_k127_2620214_2	768679.TTX_1884	9.226e-06	56.0	COG1437@1|root,arCOG01723@2157|Archaea,2XQWN@28889|Crenarchaeota	28889|Crenarchaeota	F	adenylyl cyclase CyaB	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
WLSH1_k127_2620214_1	203267.TWT_787	6.736e-11	65.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
WLSH1_k127_2632292_0	59374.Fisuc_0453	5.806e-33	130.0	COG0621@1|root,COG0621@2|Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH1_k127_2684399_1	204669.Acid345_3049	1.89e-18	89.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,SMP_2,dCache_1
WLSH1_k127_2684399_2	517418.Ctha_0500	7.842e-17	80.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1FF3J@1090|Chlorobi	1090|Chlorobi	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WLSH1_k127_2684399_0	123214.PERMA_0988	8.366e-31	124.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2G4RX@200783|Aquificae	200783|Aquificae	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WLSH1_k127_2689059_0	649764.HMPREF0762_00217	5.02e-29	120.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CUVK@84998|Coriobacteriia	84998|Coriobacteriia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WLSH1_k127_2689059_1	1343739.PAP_07460	0.0009364	50.0	COG1041@1|root,arCOG00047@2157|Archaea,2Y2EJ@28890|Euryarchaeota,2432J@183968|Thermococci	183968|Thermococci	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
WLSH1_k127_2701211_0	1449076.JOOE01000002_gene1141	2.695e-17	93.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,2K1E1@204457|Sphingomonadales	204457|Sphingomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WLSH1_k127_273260_1	1121335.Clst_1328	3.797e-48	175.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WNX9@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70 factor, region 1.2	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH1_k127_273260_0	865861.AZSU01000003_gene2059	1.841e-48	181.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,36E45@31979|Clostridiaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH1_k127_273260_3	936140.AEOT01000020_gene1545	2.074e-05	47.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli,3F3N1@33958|Lactobacillaceae	91061|Bacilli	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WLSH1_k127_273260_2	1357400.HMPREF2086_00852	3.872e-22	97.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2YMJR@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaGprimase_HBD,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WLSH1_k127_2771904_0	526218.Sterm_3675	1.271e-10	64.0	COG0796@1|root,COG0796@2|Bacteria,379AN@32066|Fusobacteria	32066|Fusobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WLSH1_k127_2771904_1	42256.RradSPS_1554	4.489e-07	52.0	COG0796@1|root,COG0796@2|Bacteria,2GN4I@201174|Actinobacteria,4CQ0N@84995|Rubrobacteria	84995|Rubrobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WLSH1_k127_2778189_0	1499684.CCNP01000020_gene2365	6.142e-05	47.0	COG0457@1|root,COG0457@2|Bacteria,1V96X@1239|Firmicutes,24AK3@186801|Clostridia,36DG6@31979|Clostridiaceae	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
WLSH1_k127_2822282_1	572477.Alvin_2805	2.152e-45	172.0	COG0840@1|root,COG0840@2|Bacteria,1R486@1224|Proteobacteria,1RZM1@1236|Gammaproteobacteria,1X2BD@135613|Chromatiales	135613|Chromatiales	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB,MCPsignal
WLSH1_k127_2822282_0	266779.Meso_3167	1.49e-57	209.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,43I8J@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WLSH1_k127_282603_0	642492.Clole_2860	7.69e-139	449.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
WLSH1_k127_290536_0	1122609.AUGT01000010_gene3709	0.0002232	53.0	COG2304@1|root,COG2304@2|Bacteria,2I5F3@201174|Actinobacteria	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cutinase,PKD
WLSH1_k127_2909839_2	1403819.BATR01000175_gene5935	2.367e-13	70.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia,2ITHR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH1_k127_2909839_0	931626.Awo_c19530	4.444e-98	326.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,25UYI@186806|Eubacteriaceae	186801|Clostridia	D	FtsK SpoIIIE family protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH1_k127_2909839_1	1154757.Q5C_09600	3.466e-18	89.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli,4AX7M@81850|Leuconostocaceae	91061|Bacilli	D	DNA segregation ATPase FtsK SpoIIIE and related proteins	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH1_k127_2919410_2	1118057.CAGX01000018_gene1382	2.328e-29	124.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,22GBR@1570339|Peptoniphilaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
WLSH1_k127_2919410_1	509635.N824_29570	5.089e-56	198.0	COG1733@1|root,COG1733@2|Bacteria,4NSVE@976|Bacteroidetes,1IYH6@117747|Sphingobacteriia	976|Bacteroidetes	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
WLSH1_k127_2919410_0	1202532.FF52_08704	6.381e-65	226.0	COG3967@1|root,COG3967@2|Bacteria,4NMPW@976|Bacteroidetes,1I7IH@117743|Flavobacteriia,2NTGD@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
WLSH1_k127_2919410_3	1506583.JQJY01000001_gene431	3.03e-22	96.0	COG3967@1|root,COG3967@2|Bacteria,4NMPW@976|Bacteroidetes,1I7IH@117743|Flavobacteriia,2NTGD@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
WLSH1_k127_2919410_7	1144313.PMI10_03848	4.695e-10	60.0	COG3967@1|root,COG3967@2|Bacteria,4NMPW@976|Bacteroidetes,1I7IH@117743|Flavobacteriia,2NTGD@237|Flavobacterium	976|Bacteroidetes	M	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K14189	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
WLSH1_k127_2919410_4	880073.Calab_1805	6.976e-17	83.0	COG1595@1|root,COG1595@2|Bacteria,2NRM3@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH1_k127_2919410_5	589865.DaAHT2_1497	6.248e-13	72.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2MKZ2@213118|Desulfobacterales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH1_k127_2919410_8	880073.Calab_1806	3.243e-09	63.0	295PX@1|root,2ZT19@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_2919410_6	381764.Fnod_1376	8.638e-12	70.0	COG4902@1|root,COG4902@2|Bacteria,2GD4X@200918|Thermotogae	200918|Thermotogae	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
WLSH1_k127_2934423_0	743836.AYNA01000126_gene1337	1.413e-101	336.0	COG2159@1|root,COG2159@2|Bacteria,1R8EW@1224|Proteobacteria,2UVN1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WLSH1_k127_2934423_2	743836.AYNA01000126_gene1337	3.223e-06	51.0	COG2159@1|root,COG2159@2|Bacteria,1R8EW@1224|Proteobacteria,2UVN1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WLSH1_k127_2934423_3	935837.JAEK01000009_gene3594	0.0008668	42.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli,1ZBW6@1386|Bacillus	91061|Bacilli	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
WLSH1_k127_2945653_4	1297617.JPJD01000032_gene2048	2.924e-07	53.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,26941@186813|unclassified Clostridiales	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WLSH1_k127_2945653_2	1122951.ATUE01000009_gene426	1.578e-24	105.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,3NNY1@468|Moraxellaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WLSH1_k127_2945653_1	273068.TTE2297	2.391e-35	139.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,42G2K@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
WLSH1_k127_2945653_0	1292033.MPUT9231_0540	3.729e-56	199.0	COG0048@1|root,COG0048@2|Bacteria,3WTGE@544448|Tenericutes	544448|Tenericutes	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
WLSH1_k127_2945653_3	1235815.BAIX01000001_gene106	2.815e-08	55.0	COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia	976|Bacteroidetes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WLSH1_k127_2954056_10	1480694.DC28_08980	3.74e-06	53.0	COG0592@1|root,COG0592@2|Bacteria,2J629@203691|Spirochaetes	203691|Spirochaetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WLSH1_k127_2954056_3	1128421.JAGA01000002_gene422	2.931e-35	144.0	COG0592@1|root,COG0592@2|Bacteria,2NP7D@2323|unclassified Bacteria	2|Bacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WLSH1_k127_2954056_9	411473.RUMCAL_02302	2.085e-08	59.0	COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,24MRX@186801|Clostridia,3WRYJ@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH1_k127_2954056_7	1487953.JMKF01000050_gene2003	3.976e-11	75.0	COG0739@1|root,COG0739@2|Bacteria,1G03M@1117|Cyanobacteria,1H9Z5@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH1_k127_2954056_6	1007096.BAGW01000014_gene1180	3.133e-14	85.0	COG4632@1|root,COG5492@1|root,COG4632@2|Bacteria,COG5492@2|Bacteria,1TQBV@1239|Firmicutes,24AWX@186801|Clostridia,2N6AF@216572|Oscillospiraceae	186801|Clostridia	GN	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,NAGPA,SLH
WLSH1_k127_2954056_5	656519.Halsa_0451	7.266e-33	132.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,3WAIP@53433|Halanaerobiales	186801|Clostridia	M	PFAM Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WLSH1_k127_2954056_2	1405.DJ92_2006	3.846e-52	187.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli,1ZASX@1386|Bacillus	91061|Bacilli	M	UTP-glucose-1-phosphate uridylyltransferase	gtaB	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WLSH1_k127_2954056_8	589924.Ferp_0187	5.195e-11	67.0	COG0719@1|root,arCOG01715@2157|Archaea,2XTY9@28890|Euryarchaeota,245RN@183980|Archaeoglobi	183980|Archaeoglobi	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
WLSH1_k127_2954056_4	1321779.HMPREF1984_00956	4.042e-33	130.0	COG0719@1|root,COG0719@2|Bacteria,378VG@32066|Fusobacteria	32066|Fusobacteria	O	feS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WLSH1_k127_2954056_1	797303.Natpe_2774	2.642e-60	211.0	COG0719@1|root,arCOG01715@2157|Archaea,2XTY9@28890|Euryarchaeota,23S0E@183963|Halobacteria	183963|Halobacteria	O	COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB1	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WLSH1_k127_2954056_0	1321779.HMPREF1984_00956	3.879e-67	233.0	COG0719@1|root,COG0719@2|Bacteria,378VG@32066|Fusobacteria	32066|Fusobacteria	O	feS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WLSH1_k127_297126_2	991.IW20_16285	0.0003512	47.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PKCK@976|Bacteroidetes,1IJ7K@117743|Flavobacteriia,2P0KA@237|Flavobacterium	976|Bacteroidetes	G	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_297126_0	269797.Mbar_A0416	8.864e-06	48.0	arCOG03561@1|root,arCOG03561@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
WLSH1_k127_298191_0	1286171.EAL2_c15700	2.268e-17	96.0	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,25WEQ@186806|Eubacteriaceae	186801|Clostridia	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
WLSH1_k127_298191_1	1128398.Curi_c03470	0.0008264	43.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia,2694A@186813|unclassified Clostridiales	186801|Clostridia	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
WLSH1_k127_2985300_0	1284708.HMPREF1634_05490	5.82e-96	325.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WCE4@538999|Clostridiales incertae sedis	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WLSH1_k127_3042268_0	1123368.AUIS01000003_gene1806	4.46e-26	108.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,LUD_dom,SnoaL_3,SnoaL_4
WLSH1_k127_3042268_3	485913.Krac_7080	1.27e-09	63.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,LUD_dom,SnoaL_3,SnoaL_4
WLSH1_k127_3042268_1	1078085.HMPREF1210_00088	3.564e-14	78.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cadherin-like,DUF3494,Glug,TIG
WLSH1_k127_3042268_2	153948.NAL212_0720	1.049e-10	66.0	2E2YT@1|root,32XZH@2|Bacteria,1MYTS@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_3091268_0	858215.Thexy_1526	7.09e-13	78.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,42F11@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WLSH1_k127_319103_0	485916.Dtox_0279	1.689e-134	440.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,260I2@186807|Peptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WLSH1_k127_3221856_0	944547.ABLL_0736	4.258e-09	59.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1PGYK@1224|Proteobacteria,42YPW@68525|delta/epsilon subdivisions,2YR2J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_9
WLSH1_k127_3221856_1	697282.Mettu_0629	0.0005305	48.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
WLSH1_k127_3226677_0	1267533.KB906741_gene635	5.19e-125	408.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WLSH1_k127_3254728_1	76114.ebA1527	2.047e-08	56.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2VM0Z@28216|Betaproteobacteria,2KZAK@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WLSH1_k127_3254728_2	926550.CLDAP_10380	3.363e-06	50.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH1_k127_3254728_0	935840.JAEQ01000007_gene3975	3.541e-29	125.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2U0DX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH1_k127_3272782_0	1303518.CCALI_01954	1.378e-92	316.0	COG0536@1|root,COG0536@2|Bacteria	2|Bacteria	C	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043021,GO:0043022,GO:0043167,GO:0043168,GO:0043934,GO:0044424,GO:0044464,GO:0044877,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
WLSH1_k127_3274120_3	401526.TcarDRAFT_1293	1.716e-05	49.0	COG0503@1|root,COG0741@1|root,COG0503@2|Bacteria,COG0741@2|Bacteria,1TSYQ@1239|Firmicutes,4H5A6@909932|Negativicutes	909932|Negativicutes	F	protein secretion by the type IV secretion system	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WLSH1_k127_3274120_2	288705.RSal33209_2445	2.57e-06	50.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,1W871@1268|Micrococcaceae	201174|Actinobacteria	C	Malate dehydrogenase	mez_1	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
WLSH1_k127_3274120_0	877424.ATWC01000014_gene2592	2.004e-139	451.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,27ISX@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
WLSH1_k127_3274120_1	1123054.KB907720_gene3231	9.484e-88	299.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WX5F@135613|Chromatiales	135613|Chromatiales	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
WLSH1_k127_3289909_0	1121267.JHZL01000001_gene678	9.533e-11	64.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2YMQJ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WLSH1_k127_3289909_1	1304878.AUGD01000007_gene5501	1.025e-09	71.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,2U0VF@28211|Alphaproteobacteria,3JVUJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
WLSH1_k127_3289909_2	675806.VII_002067	8.12e-07	53.0	COG0845@1|root,COG0845@2|Bacteria,1R4JA@1224|Proteobacteria,1RPS5@1236|Gammaproteobacteria,1XU26@135623|Vibrionales	135623|Vibrionales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH1_k127_3311236_1	1247024.JRLH01000001_gene853	0.0002999	44.0	2DRC0@1|root,33B61@2|Bacteria,1NHS4@1224|Proteobacteria,1SGUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_3311236_0	694427.Palpr_3018	5.503e-29	130.0	COG1835@1|root,COG1835@2|Bacteria,4NMNZ@976|Bacteroidetes,2FP9R@200643|Bacteroidia,231KY@171551|Porphyromonadaceae	976|Bacteroidetes	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
WLSH1_k127_333500_0	397948.Cmaq_1100	5.915e-22	106.0	COG1032@1|root,arCOG01356@2157|Archaea,2XQ4W@28889|Crenarchaeota	28889|Crenarchaeota	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
WLSH1_k127_3352598_0	517418.Ctha_0161	5.738e-119	388.0	COG0069@1|root,COG1773@1|root,COG0069@2|Bacteria,COG1773@2|Bacteria,1FDGS@1090|Chlorobi	1090|Chlorobi	C	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rubredoxin
WLSH1_k127_3366075_1	580332.Slit_2306	2.403e-21	96.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
WLSH1_k127_3366075_0	1304885.AUEY01000009_gene1980	8.467e-45	172.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	BON,OMP_b-brl,OmpA
WLSH1_k127_3487619_2	592031.GCWU000322_00806	0.0002543	44.0	COG2184@1|root,COG2184@2|Bacteria,1TNY6@1239|Firmicutes,249XE@186801|Clostridia,25VWH@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
WLSH1_k127_3487619_0	243274.THEMA_00695	3.076e-42	159.0	COG0780@1|root,COG0780@2|Bacteria,2GDDY@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
WLSH1_k127_3487619_1	445970.ALIPUT_02210	1.828e-37	145.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FWBI@200643|Bacteroidia,22UYK@171550|Rikenellaceae	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH1_k127_3490146_6	425400.LS65_02640	2.365e-10	64.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2YMZZ@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Ribonuclease	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB
WLSH1_k127_3490146_7	1408226.T233_00370	7.615e-07	54.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,4AZE8@81852|Enterococcaceae	91061|Bacilli	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WLSH1_k127_3490146_5	742740.HMPREF9474_01537	2.128e-10	67.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,21XUX@1506553|Lachnoclostridium	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WLSH1_k127_3490146_0	1410632.JHWW01000007_gene531	7.972e-212	666.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,27IDF@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WLSH1_k127_3490146_4	765420.OSCT_1155	3.637e-11	69.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi,375QG@32061|Chloroflexia	32061|Chloroflexia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
WLSH1_k127_3490146_2	469618.FVAG_01929	3.065e-23	106.0	COG4122@1|root,COG4122@2|Bacteria,379F0@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
WLSH1_k127_3490146_1	1353529.M899_0022	6.89e-28	121.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2MSM0@213481|Bdellovibrionales,2WIVR@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH1_k127_3490146_3	883096.HMPREF9699_00263	1.081e-11	65.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1HWS4@117743|Flavobacteriia	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH1_k127_3499055_1	909663.KI867150_gene1241	1.141e-53	192.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2MQFZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
WLSH1_k127_3499055_0	909663.KI867150_gene1242	2.651e-59	211.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2MRZT@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WLSH1_k127_3541286_0	338963.Pcar_0406	2.858e-108	369.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,43S27@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Bacterial DNA topoisomeraes I ATP-binding domain	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WLSH1_k127_3541286_1	717772.THIAE_09715	6.034e-87	291.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,4608B@72273|Thiotrichales	72273|Thiotrichales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
WLSH1_k127_3568604_1	296587.XP_002504075.1	4.675e-06	49.0	2D47E@1|root,2SU67@2759|Eukaryota,389V8@33090|Viridiplantae,34PF7@3041|Chlorophyta	296587.XP_002504075.1|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_3568604_0	1298593.TOL_1818	1.26e-38	147.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,1RNPY@1236|Gammaproteobacteria,1XHJ5@135619|Oceanospirillales	135619|Oceanospirillales	O	protease	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
WLSH1_k127_3610327_2	411459.RUMOBE_00450	1.218e-05	54.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,3Y15H@572511|Blautia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
WLSH1_k127_3610327_1	909943.HIMB100_00006050	1.839e-09	67.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,4BPDJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WLSH1_k127_3610327_0	1123242.JH636434_gene4906	1.813e-26	111.0	COG0260@1|root,COG0260@2|Bacteria,2IY4Q@203682|Planctomycetes	203682|Planctomycetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WLSH1_k127_3653460_0	574087.Acear_2144	3.133e-49	187.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia,3WAC4@53433|Halanaerobiales	186801|Clostridia	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
WLSH1_k127_3670757_0	1121936.AUHI01000012_gene1230	1.675e-47	177.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli	91061|Bacilli	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
WLSH1_k127_3670757_1	324057.Pjdr2_3898	9.398e-42	160.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,26RFS@186822|Paenibacillaceae	91061|Bacilli	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WLSH1_k127_3750982_1	1262915.BN574_00289	2.528e-48	177.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,4H1VZ@909932|Negativicutes	909932|Negativicutes	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH1_k127_3750982_2	445971.ANASTE_00259	3.843e-28	114.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,25URN@186806|Eubacteriaceae	186801|Clostridia	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH1_k127_3750982_0	445971.ANASTE_00259	1.795e-61	217.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,25URN@186806|Eubacteriaceae	186801|Clostridia	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH1_k127_3751192_1	702450.CUW_1691	4.959e-33	132.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,3VNST@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WLSH1_k127_3751192_5	1007096.BAGW01000006_gene1863	2.29e-09	65.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,2N77Z@216572|Oscillospiraceae	186801|Clostridia	J	Ribosomal protein L9, N-terminal domain	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WLSH1_k127_3751192_4	944480.ATUV01000002_gene277	1.524e-16	84.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2M79G@213113|Desulfurellales	28221|Deltaproteobacteria	L	Likely ribonuclease with RNase H fold.	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WLSH1_k127_3751192_6	1354300.AUQY01000002_gene824	3.523e-09	57.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,22GS6@1570339|Peptoniphilaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WLSH1_k127_3751192_0	1123376.AUIU01000013_gene1793	3.556e-33	133.0	COG0020@1|root,COG0020@2|Bacteria,3J0HJ@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WLSH1_k127_3751192_2	944480.ATUV01000001_gene632	3.526e-28	117.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2WP5B@28221|Deltaproteobacteria,2M76K@213113|Desulfurellales	28221|Deltaproteobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WLSH1_k127_3751192_7	1118059.CAHC01000012_gene385	0.0002926	46.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WCIW@538999|Clostridiales incertae sedis	186801|Clostridia	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH1_k127_3751192_3	941824.TCEL_01868	1.163e-19	94.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,36DFF@31979|Clostridiaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH1_k127_3765678_4	526222.Desal_0134	1.793e-07	57.0	COG0694@1|root,COG0822@1|root,COG0694@2|Bacteria,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2M82B@213115|Desulfovibrionales	28221|Deltaproteobacteria	CO	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins	nifU	-	-	ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
WLSH1_k127_3765678_2	1215092.PA6_067_00070	2.056e-14	76.0	COG0642@1|root,COG2205@2|Bacteria,1QU03@1224|Proteobacteria,1T1JP@1236|Gammaproteobacteria,1YEIN@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WLSH1_k127_3765678_3	660470.Theba_1301	1.598e-10	69.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WLSH1_k127_3765678_5	1331660.L313_0309	6.045e-05	46.0	COG0745@1|root,COG0745@2|Bacteria,1RA6Z@1224|Proteobacteria,1SYDG@1236|Gammaproteobacteria,3NTB6@468|Moraxellaceae	1236|Gammaproteobacteria	KT	Transcriptional regulatory protein, C terminal	qseB	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_3765678_0	1401067.HMPREF0872_07525	3.135e-21	95.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H8V0@909932|Negativicutes	909932|Negativicutes	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_3765678_1	411489.CLOL250_02965	2.839e-17	82.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,36EH1@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_3833961_4	558884.JRGM01000178_gene2604	8.385e-06	50.0	COG2755@1|root,COG2755@2|Bacteria,1QV1E@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_fiber_2,SASA
WLSH1_k127_3833961_3	1292035.H476_2996	2.515e-06	51.0	COG5492@1|root,COG5492@2|Bacteria,1V17S@1239|Firmicutes,24GRG@186801|Clostridia	186801|Clostridia	N	S-layer domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,SLH
WLSH1_k127_3833961_1	1382358.JHVN01000002_gene2339	2.097e-13	75.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,21W76@150247|Anoxybacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WLSH1_k127_3833961_0	1097668.BYI23_C002750	3.447e-15	76.0	COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,2VJ81@28216|Betaproteobacteria,1K5DI@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH1_k127_3833961_6	290512.Paes_0204	0.0001834	50.0	COG1262@1|root,COG1680@1|root,COG1262@2|Bacteria,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase,Fib_succ_major,TIR_2
WLSH1_k127_3833961_2	86416.Clopa_3415	4.144e-07	53.0	COG2165@1|root,COG2165@2|Bacteria,1VK8F@1239|Firmicutes,24UDT@186801|Clostridia	186801|Clostridia	NU	prepilin-type N-terminal cleavage methylation domain	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl
WLSH1_k127_3837814_0	1499967.BAYZ01000028_gene1279	1.359e-29	123.0	COG0635@1|root,COG0635@2|Bacteria,2NRKI@2323|unclassified Bacteria	2|Bacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,NUDIX,Radical_SAM
WLSH1_k127_3837814_2	240292.Ava_2941	1.175e-20	101.0	COG4339@1|root,COG4339@2|Bacteria,1G5Q9@1117|Cyanobacteria,1HJAE@1161|Nostocales	1117|Cyanobacteria	S	COGs COG4339 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_3837814_3	1289135.A966_04281	2.087e-14	83.0	COG0669@1|root,COG0669@2|Bacteria,2J7VS@203691|Spirochaetes	203691|Spirochaetes	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH1_k127_3837814_1	93612.XP_008025341.1	3.861e-22	105.0	COG1335@1|root,KOG4003@2759|Eukaryota,39V1V@33154|Opisthokonta,3NYNG@4751|Fungi,3QSWQ@4890|Ascomycota,201NG@147541|Dothideomycetes,4KEID@92860|Pleosporales	4751|Fungi	V	Isochorismatase family	PNC1	GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005777,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0042579,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1904523,GO:1904524,GO:2000112,GO:2000113,GO:2000278,GO:2000279,GO:2001141	3.5.1.19	ko:K01440	ko00760,ko01100,ko04213,map00760,map01100,map04213	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
WLSH1_k127_38509_0	272562.CA_C2687	7.525e-13	76.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,36DC9@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
WLSH1_k127_3851680_1	1121472.AQWN01000009_gene355	5.434e-46	173.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,2603X@186807|Peptococcaceae	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH1_k127_3851680_0	555088.DealDRAFT_0765	1.961e-53	194.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42KEX@68298|Syntrophomonadaceae	186801|Clostridia	NU	General secretory system II protein E domain protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH1_k127_3874033_0	1283300.ATXB01000001_gene618	7.097e-55	199.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1XEGS@135618|Methylococcales	135618|Methylococcales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WLSH1_k127_3874033_1	929562.Emtol_0508	4.315e-17	81.0	COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,47P74@768503|Cytophagia	976|Bacteroidetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
WLSH1_k127_3888693_0	693746.OBV_20800	8.388e-12	69.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,2N6FP@216572|Oscillospiraceae	186801|Clostridia	M	UDP-N-acetylenolpyruvoylglucosamine reductase	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WLSH1_k127_3888693_1	598659.NAMH_0270	3.243e-07	53.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2YN53@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iIT341.HP1418	MurB_C
WLSH1_k127_3888693_2	592029.DDD_1881	4.287e-07	53.0	COG1943@1|root,COG1943@2|Bacteria,4NPWC@976|Bacteroidetes,1I28P@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WLSH1_k127_3888693_3	945713.IALB_1198	0.0001527	46.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WLSH1_k127_3895639_0	1121405.dsmv_2804	1.367e-228	713.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2MI3V@213118|Desulfobacterales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WLSH1_k127_3937012_2	945713.IALB_0486	4.477e-08	57.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WLSH1_k127_3937012_0	338963.Pcar_0432	1.366e-73	252.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,43UYD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
WLSH1_k127_3937012_1	610130.Closa_0928	1.042e-68	246.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia,21YXH@1506553|Lachnoclostridium	186801|Clostridia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WLSH1_k127_3939421_2	1157490.EL26_13300	2.09e-29	121.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli,277VM@186823|Alicyclobacillaceae	91061|Bacilli	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WLSH1_k127_3939421_3	1437600.JDUI01000007_gene768	2.031e-17	83.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CZU1@85004|Bifidobacteriales	201174|Actinobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WLSH1_k127_3939421_0	649349.Lbys_1940	7.102e-62	228.0	COG4487@1|root,COG4487@2|Bacteria,4NGZ9@976|Bacteroidetes,47MY2@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2130)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
WLSH1_k127_3939421_1	469604.HMPREF0946_00895	4.542e-55	202.0	COG0116@1|root,COG0116@2|Bacteria,378K7@32066|Fusobacteria	32066|Fusobacteria	L	Putative RNA methylase family UPF0020	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
WLSH1_k127_3941573_0	1162668.LFE_1113	5.374e-25	114.0	COG3391@1|root,COG3391@2|Bacteria,3J19W@40117|Nitrospirae	40117|Nitrospirae	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
WLSH1_k127_3941573_1	2903.EOD12963	2.03e-22	106.0	KOG2177@1|root,KOG2177@2759|Eukaryota	2759|Eukaryota	O	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	BTB,Lactonase,NHL,SGL
WLSH1_k127_3988431_0	1395513.P343_08515	2.063e-36	150.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli,26P9P@186821|Sporolactobacillaceae	91061|Bacilli	S	ABC transporter	yfmM	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WLSH1_k127_3988431_1	1282887.AUJG01000005_gene218	1.9e-19	93.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH1_k127_4029056_0	269797.Mbar_A1407	3.221e-93	321.0	COG3547@1|root,arCOG03585@2157|Archaea,2XWFH@28890|Euryarchaeota	28890|Euryarchaeota	L	COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
WLSH1_k127_4045115_0	1249480.B649_05555	1.135e-137	437.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2YMJV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WLSH1_k127_4045115_1	1249480.B649_05560	6.654e-101	330.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2YNXC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iIT341.HP0618	ADK
WLSH1_k127_4065153_1	1121271.AUCM01000003_gene1449	1.402e-23	100.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
WLSH1_k127_4065153_0	1348114.OM33_04865	5.772e-33	140.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,2Q0X8@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH1_k127_4098014_1	1191523.MROS_1111	3.135e-08	55.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
WLSH1_k127_4098014_0	1191523.MROS_1110	3.184e-113	373.0	COG2461@1|root,COG2461@2|Bacteria	2|Bacteria	P	Hemerythrin HHE cation binding domain protein	XK27_04775	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
WLSH1_k127_4120193_0	880073.Calab_0118	0.0002591	54.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.89	ko:K01224,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DctA-YdbH,Laminin_G_3
WLSH1_k127_4251294_0	765420.OSCT_0924	2.136e-31	134.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF
WLSH1_k127_4251294_1	388467.A19Y_2623	2.374e-07	58.0	2E4CS@1|root,32Z87@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_427105_0	880073.Calab_1915	4.587e-52	188.0	COG1159@1|root,COG1159@2|Bacteria,2NP0U@2323|unclassified Bacteria	2|Bacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113	-	ko:K03595,ko:K06883	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WLSH1_k127_427105_1	945713.IALB_2378	4.396e-35	140.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	pagO	-	-	ko:K07790	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.7	-	-	EamA
WLSH1_k127_4277004_0	1120985.AUMI01000004_gene1358	2.746e-244	780.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4H26H@909932|Negativicutes	909932|Negativicutes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH1_k127_4277004_2	1123242.JH636434_gene3222	1.584e-07	60.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,2IYXB@203682|Planctomycetes	203682|Planctomycetes	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_16,TPR_2,TPR_6,TPR_8
WLSH1_k127_4277004_1	485913.Krac_12284	1.424e-16	90.0	COG0849@1|root,COG0849@2|Bacteria	2|Bacteria	D	cell division	-	-	-	-	-	-	-	-	-	-	-	-	FtsA
WLSH1_k127_429474_5	457398.HMPREF0326_02352	3.883e-05	50.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2WRHX@28221|Deltaproteobacteria,2MCG1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
WLSH1_k127_429474_3	1424334.W822_21230	4.063e-19	94.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,3T1YQ@506|Alcaligenaceae	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WLSH1_k127_429474_4	697329.Rumal_3051	1.803e-16	81.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WLSH1_k127_429474_2	1449126.JQKL01000021_gene77	2.775e-20	93.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2682V@186813|unclassified Clostridiales	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WLSH1_k127_429474_0	758.BBIX01000006_gene711	3.002e-95	321.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1Y6WZ@135625|Pasteurellales	135625|Pasteurellales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WLSH1_k127_429474_1	518766.Rmar_2465	1.779e-58	208.0	COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,1FISE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WLSH1_k127_4369546_1	304371.MCP_1254	1.125e-18	91.0	COG1989@1|root,arCOG02298@2157|Archaea,2XUQP@28890|Euryarchaeota,2N9XX@224756|Methanomicrobia	224756|Methanomicrobia	N	Peptidase A24A, prepilin type IV	-	-	3.4.23.52	ko:K07991	-	-	-	-	ko00000,ko01000,ko01002,ko02035,ko02044	-	-	-	Arc_PepC_II,Peptidase_A24
WLSH1_k127_4369546_0	351160.LRC468	3.319e-49	179.0	COG0484@1|root,arCOG02846@2157|Archaea,2XV5D@28890|Euryarchaeota,2N95Q@224756|Methanomicrobia	224756|Methanomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH1_k127_4423898_0	864565.HMPREF0379_0814	1.01e-20	92.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,25T4Y@186804|Peptostreptococcaceae	186801|Clostridia	NOU	Bacterial Peptidase A24 N-terminal domain	hofD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WLSH1_k127_4423898_1	515635.Dtur_1026	4.477e-08	57.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WLSH1_k127_4445179_0	933262.AXAM01000010_gene1379	1.113e-06	59.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2MJMG@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WLSH1_k127_4453291_0	926569.ANT_19510	6.234e-15	85.0	COG0451@1|root,COG0451@2|Bacteria,2G74B@200795|Chloroflexi	200795|Chloroflexi	GM	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
WLSH1_k127_4456273_3	378806.STAUR_4644	6.253e-09	60.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YY0K@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1
WLSH1_k127_4456273_2	639030.JHVA01000001_gene1258	2.419e-12	68.0	COG0223@1|root,COG0223@2|Bacteria,3Y32C@57723|Acidobacteria,2JHUK@204432|Acidobacteriia	204432|Acidobacteriia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WLSH1_k127_4456273_0	351627.Csac_2081	3.887e-38	146.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,42FC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WLSH1_k127_4456273_1	765420.OSCT_2672	1.934e-16	84.0	COG0628@1|root,COG0628@2|Bacteria,2G712@200795|Chloroflexi,375FE@32061|Chloroflexia	32061|Chloroflexia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WLSH1_k127_4488668_2	485918.Cpin_1629	4.272e-27	115.0	COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,1IS0B@117747|Sphingobacteriia	976|Bacteroidetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
WLSH1_k127_4488668_5	573370.DMR_12330	3.408e-14	76.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2MD30@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
WLSH1_k127_4488668_0	684719.HIMB114_00004110	5.765e-51	186.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2TQPF@28211|Alphaproteobacteria,4BQ1I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
WLSH1_k127_4488668_3	867902.Ornrh_0463	1.474e-26	113.0	COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,1I2VR@117743|Flavobacteriia	976|Bacteroidetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
WLSH1_k127_4488668_1	1408323.JQKK01000014_gene105	2.174e-47	172.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,27MQ8@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
WLSH1_k127_4488668_4	316274.Haur_4923	1.221e-18	87.0	COG0186@1|root,COG0186@2|Bacteria,2G722@200795|Chloroflexi,375WC@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
WLSH1_k127_4493817_2	264731.PRU_0991	1.905e-14	74.0	COG0514@1|root,COG0514@2|Bacteria,4NG10@976|Bacteroidetes,2FPSQ@200643|Bacteroidia	976|Bacteroidetes	L	ATP-dependent DNA helicase	recQ3	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
WLSH1_k127_4493817_1	1304880.JAGB01000003_gene1153	1.602e-21	95.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
WLSH1_k127_4493817_0	1396141.BATP01000022_gene456	5.974e-47	175.0	COG0514@1|root,COG0514@2|Bacteria,46U82@74201|Verrucomicrobia,2ITT4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RQC	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
WLSH1_k127_4493817_3	1313301.AUGC01000001_gene1423	0.0004157	50.0	COG0514@1|root,COG0514@2|Bacteria,4NEFD@976|Bacteroidetes	976|Bacteroidetes	L	ATP-dependent DNA helicase RecQ	recQ2	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
WLSH1_k127_4513344_2	1313293.BAN_0114400	0.0003525	44.0	COG0180@1|root,COG0180@2|Bacteria,2J68U@203691|Spirochaetes	203691|Spirochaetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WLSH1_k127_4513344_0	643867.Ftrac_0103	5.813e-22	99.0	2C6BU@1|root,32S87@2|Bacteria,4NRX1@976|Bacteroidetes,47R4G@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_4513344_1	596154.Alide2_2722	2.489e-12	71.0	2C6BU@1|root,32S87@2|Bacteria,1NIFE@1224|Proteobacteria,2VRGB@28216|Betaproteobacteria,4AGT5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_4519229_0	1123253.AUBD01000005_gene107	2.735e-74	259.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,1RMN0@1236|Gammaproteobacteria,1X3I1@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
WLSH1_k127_4519229_1	1380370.JIBA01000016_gene675	0.000838	46.0	COG0438@1|root,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4FEYY@85021|Intrasporangiaceae	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH1_k127_4526842_0	580340.Tlie_1429	3.861e-53	191.0	COG0168@1|root,COG0168@2|Bacteria,3T9WI@508458|Synergistetes	508458|Synergistetes	P	Potassium uptake protein, TrkH family	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WLSH1_k127_4526842_1	1121904.ARBP01000003_gene6423	6.766e-49	179.0	COG0168@1|root,COG0168@2|Bacteria,4NGMF@976|Bacteroidetes,47JH5@768503|Cytophagia	976|Bacteroidetes	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WLSH1_k127_4540273_0	373903.Hore_00650	1.597e-22	102.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WA5Y@53433|Halanaerobiales	186801|Clostridia	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
WLSH1_k127_4540273_1	446470.Snas_5142	2.234e-07	52.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4EY90@85014|Glycomycetales	201174|Actinobacteria	O	PDZ domain (Also known as DHR or GLGF)	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
WLSH1_k127_4540273_3	691883.XP_009493491.1	0.0008007	44.0	COG0265@1|root,KOG1320@2759|Eukaryota,38G0B@33154|Opisthokonta	33154|Opisthokonta	O	pentacyclic triterpenoid metabolic process	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH1_k127_4540273_2	439235.Dalk_3706	0.0002382	50.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2MHQQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	degP-2	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH1_k127_4541519_1	351016.RAZWK3B_10752	6.561e-18	85.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,2P1HU@2433|Roseobacter	28211|Alphaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WLSH1_k127_4541519_0	1179226.AJXO01000033_gene1177	6.194e-21	94.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli,4GZK2@90964|Staphylococcaceae	91061|Bacilli	L	endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH1_k127_4543014_1	545694.TREPR_1796	7.678e-11	66.0	COG2348@1|root,COG2348@2|Bacteria,2J58H@203691|Spirochaetes	203691|Spirochaetes	V	Methicillin resistance protein	femA	-	-	-	-	-	-	-	-	-	-	-	FemAB
WLSH1_k127_4543014_0	351627.Csac_2154	4.682e-41	154.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,42ET2@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WLSH1_k127_4608333_0	1157635.KB892001_gene2698	3.019e-05	51.0	COG1653@1|root,COG1653@2|Bacteria,2GKM8@201174|Actinobacteria	201174|Actinobacteria	G	PFAM extracellular solute-binding protein family 1	dasA	-	-	ko:K17329	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
WLSH1_k127_4643444_0	990073.ATHU01000001_gene761	3.512e-39	152.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2YN57@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WLSH1_k127_4643444_1	1323663.AROI01000015_gene551	8.862e-08	60.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtC	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WLSH1_k127_4726579_0	927658.AJUM01000047_gene2869	4.778e-95	321.0	COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia,3XJVQ@558415|Marinilabiliaceae	976|Bacteroidetes	H	Domain of unknown function (DUF4301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4301
WLSH1_k127_4773242_3	759362.KVU_0640	5.313e-14	75.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WLSH1_k127_4773242_0	552811.Dehly_0754	8.488e-23	103.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi,34DBK@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH1_k127_4773242_4	1319815.HMPREF0202_01508	4.755e-12	69.0	COG0360@1|root,COG0360@2|Bacteria,37APH@32066|Fusobacteria	32066|Fusobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WLSH1_k127_4773242_2	62928.azo3158	8.932e-17	83.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,2VRNX@28216|Betaproteobacteria,2KWBG@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulatory protein, C terminal	colR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_4773242_1	469618.FVAG_00150	1.48e-19	91.0	COG0745@1|root,COG0745@2|Bacteria,379HE@32066|Fusobacteria	32066|Fusobacteria	K	Psort location Cytoplasmic, score 9.97	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_4823642_1	1123405.AUMM01000015_gene2399	2.568e-08	61.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,4HCJ2@91061|Bacilli,26PRR@186821|Sporolactobacillaceae	91061|Bacilli	S	Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
WLSH1_k127_4823642_0	1121104.AQXH01000004_gene23	2.512e-27	118.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes	976|Bacteroidetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WLSH1_k127_4872659_1	1047013.AQSP01000130_gene1863	5.361e-33	135.0	28KQH@1|root,2ZA8A@2|Bacteria	2|Bacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
WLSH1_k127_4872659_0	1379698.RBG1_1C00001G0607	4.727e-43	167.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
WLSH1_k127_4897199_1	1276920.ADIAG_03912	1.382e-07	55.0	COG0607@1|root,COG0607@2|Bacteria,2IQJQ@201174|Actinobacteria	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH1_k127_4897199_0	268407.PWYN_17235	6.804e-90	318.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli,26RXA@186822|Paenibacillaceae	91061|Bacilli	JKL	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity	cshA	GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
WLSH1_k127_4923367_0	59374.Fisuc_2482	1.008e-103	342.0	COG0112@1|root,COG0112@2|Bacteria	2|Bacteria	E	glycine hydroxymethyltransferase activity	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081	SHMT
WLSH1_k127_4923367_5	1244528.CFT03427_1152	6.473e-13	69.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2YM9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WLSH1_k127_4923367_2	1163745.HCD_01375	2.218e-63	226.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2YM9U@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WLSH1_k127_4923367_4	1122915.AUGY01000062_gene4437	7.505e-31	125.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli,26YJD@186822|Paenibacillaceae	91061|Bacilli	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH1_k127_4923367_6	207559.Dde_2039	0.0005513	51.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2M8WH@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH1_k127_4923367_1	1341151.ASZU01000021_gene1201	1.618e-72	254.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli,27AZA@186824|Thermoactinomycetaceae	91061|Bacilli	L	TRCF	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH1_k127_4923367_3	1242864.D187_001969	2.469e-32	129.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2YUID@29|Myxococcales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH1_k127_4937256_2	941824.TCEL_01715	1.016e-21	98.0	COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,36F0B@31979|Clostridiaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
WLSH1_k127_4937256_4	457396.CSBG_01165	1.053e-15	79.0	COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,36F0B@31979|Clostridiaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
WLSH1_k127_4937256_0	1176165.CAJD01000012_gene695	1.36e-42	174.0	COG1215@1|root,COG1215@2|Bacteria,2IK1V@201174|Actinobacteria,4F9BY@85019|Brevibacteriaceae	201174|Actinobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_4937256_1	711393.AYRX01000079_gene5577	3.403e-23	105.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria	201174|Actinobacteria	KT	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WLSH1_k127_4937256_3	1387312.BAUS01000002_gene949	1.403e-18	89.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,2KM54@206350|Nitrosomonadales	206350|Nitrosomonadales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WLSH1_k127_4939302_0	647113.Metok_0325	5.591e-07	62.0	COG5410@1|root,arCOG09550@2157|Archaea,2XW1V@28890|Euryarchaeota,23QCA@183939|Methanococci	183939|Methanococci	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
WLSH1_k127_4944671_1	938289.CAJN020000003_gene1031	3.255e-53	189.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,26808@186813|unclassified Clostridiales	186801|Clostridia	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WLSH1_k127_4944671_2	997350.HMPREF9129_0158	2.416e-29	121.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,22FWX@1570339|Peptoniphilaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WLSH1_k127_4944671_0	1111454.HMPREF1250_1264	5.747e-66	232.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4H228@909932|Negativicutes	909932|Negativicutes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WLSH1_k127_4944671_3	1429851.X548_12415	0.0002789	50.0	COG1574@1|root,COG1574@2|Bacteria,1NHEU@1224|Proteobacteria,1SHYG@1236|Gammaproteobacteria,1X95G@135614|Xanthomonadales	135614|Xanthomonadales	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_4955217_0	696369.KI912183_gene2430	4.305e-162	519.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,25ZXZ@186807|Peptococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WLSH1_k127_4955217_1	33905.BTHE_0892	3.701e-96	327.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WLSH1_k127_4974559_3	439235.Dalk_3387	2.238e-07	53.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,42ZT9@68525|delta/epsilon subdivisions,2WUUI@28221|Deltaproteobacteria,2MNC0@213118|Desulfobacterales	28221|Deltaproteobacteria	H	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C
WLSH1_k127_4974559_1	1353529.M899_2677	7.485e-17	93.0	COG0729@1|root,COG0729@2|Bacteria,1QY1J@1224|Proteobacteria,430S6@68525|delta/epsilon subdivisions,2MU2E@213481|Bdellovibrionales,2WVNT@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
WLSH1_k127_4974559_0	1246445.ANAY01000021_gene1741	5.716e-62	218.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,4EGW8@85012|Streptosporangiales	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH1_k127_4974559_2	469617.FUAG_01535	8.294e-12	65.0	COG0154@1|root,COG0154@2|Bacteria,3783S@32066|Fusobacteria	32066|Fusobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH1_k127_4976144_0	357808.RoseRS_0580	2.294e-16	86.0	COG0472@1|root,COG0472@2|Bacteria,2G6H5@200795|Chloroflexi,375CW@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_4
WLSH1_k127_4976144_1	635013.TherJR_1751	1.724e-08	59.0	COG2165@1|root,COG2165@2|Bacteria,1VK8F@1239|Firmicutes,25GH3@186801|Clostridia,267EJ@186807|Peptococcaceae	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
WLSH1_k127_4990482_2	638303.Thal_0220	0.0003987	44.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G3KI@200783|Aquificae	200783|Aquificae	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WLSH1_k127_4990482_1	411462.DORLON_00555	4.871e-35	139.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,27UT3@189330|Dorea	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
WLSH1_k127_4990482_0	868595.Desca_0931	6.734e-58	205.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,26146@186807|Peptococcaceae	186801|Clostridia	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
WLSH1_k127_5007688_0	523850.TON_1907	2.573e-27	121.0	COG1404@1|root,arCOG00702@2157|Archaea,2XSZR@28890|Euryarchaeota,243UH@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH1_k127_5044551_0	641146.HMPREF9020_00761	2.093e-43	168.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,4CZ9X@85004|Bifidobacteriales	201174|Actinobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WLSH1_k127_5124730_1	269799.Gmet_1227	4.03e-27	112.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WMSH@28221|Deltaproteobacteria,43U4F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH1_k127_5124730_0	90814.KL370891_gene1555	5.391e-31	126.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,45ZW9@72273|Thiotrichales	72273|Thiotrichales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH1_k127_5124730_2	1121935.AQXX01000126_gene932	6.439e-08	56.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,1RSHC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid,zf-TFIIB
WLSH1_k127_5148774_0	1270196.JCKI01000009_gene3311	4.8e-15	78.0	COG1605@1|root,COG1605@2|Bacteria,4P863@976|Bacteroidetes,1IZWG@117747|Sphingobacteriia	976|Bacteroidetes	E	Chorismate mutase type II	-	-	-	-	-	-	-	-	-	-	-	-	CM_2
WLSH1_k127_5148774_1	1123270.ATUR01000002_gene2252	1.956e-14	74.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,2UFDJ@28211|Alphaproteobacteria,2K59J@204457|Sphingomonadales	204457|Sphingomonadales	P	PhnA protein	-	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA
WLSH1_k127_516206_0	871968.DESME_00645	1.405e-74	269.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,2602M@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
WLSH1_k127_5269453_0	1184267.A11Q_1026	1.024e-90	307.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2MSM9@213481|Bdellovibrionales,2WKBA@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WLSH1_k127_5269453_1	1408254.T458_17170	1.132e-12	72.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli,26QT4@186822|Paenibacillaceae	91061|Bacilli	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WLSH1_k127_5269453_2	1123511.KB905844_gene1246	6.096e-11	69.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4H27E@909932|Negativicutes	909932|Negativicutes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WLSH1_k127_5337848_0	272623.L84502	1.198e-32	134.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli,1YBBD@1357|Lactococcus	91061|Bacilli	K	Tex-like protein N-terminal domain	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
WLSH1_k127_5351769_2	1120973.AQXL01000096_gene3018	0.0005324	49.0	COG4926@1|root,COG4926@2|Bacteria,1U67P@1239|Firmicutes,4HAN5@91061|Bacilli	91061|Bacilli	L	Phage minor structural protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,Prophage_tail
WLSH1_k127_5351769_0	1125699.HMPREF9194_01175	1.526e-14	77.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WLSH1_k127_5351769_1	1122132.AQYH01000002_gene1445	0.0003881	44.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,4B8NI@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WLSH1_k127_5354643_0	398767.Glov_1103	1.111e-19	96.0	COG2888@1|root,COG2888@2|Bacteria,1MZH3@1224|Proteobacteria,42VBG@68525|delta/epsilon subdivisions,2WTZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_5406392_0	1042156.CXIVA_15510	0.0002677	44.0	COG0514@1|root,COG0514@2|Bacteria	2|Bacteria	L	ATP-dependent DNA helicase (RecQ)	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
WLSH1_k127_5420743_0	1123325.JHUV01000009_gene474	5.194e-69	240.0	COG2107@1|root,COG2107@2|Bacteria,2G4EE@200783|Aquificae	200783|Aquificae	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
WLSH1_k127_5428425_0	926569.ANT_09980	2.19e-113	378.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WLSH1_k127_5429950_1	393480.FNP_1252	5.348e-05	53.0	COG0457@1|root,COG4282@1|root,COG0457@2|Bacteria,COG4282@2|Bacteria,37B6Y@32066|Fusobacteria	32066|Fusobacteria	G	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_16,TPR_8
WLSH1_k127_5429950_0	1430440.MGMSRv2_2695	8.732e-35	136.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,2JPIQ@204441|Rhodospirillales	204441|Rhodospirillales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WLSH1_k127_5437095_1	1189612.A33Q_3691	1.083e-05	51.0	COG0640@1|root,COG0640@2|Bacteria,4NS23@976|Bacteroidetes,47UMU@768503|Cytophagia	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_5437095_0	1134413.ANNK01000167_gene529	7.61e-29	124.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,4HIMM@91061|Bacilli,1ZDPJ@1386|Bacillus	91061|Bacilli	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WLSH1_k127_5449968_0	880073.Calab_0503	5.165e-84	287.0	COG0826@1|root,COG0826@2|Bacteria,2NPQH@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
WLSH1_k127_5449968_3	926549.KI421517_gene787	5.163e-46	170.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47J9E@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WLSH1_k127_5449968_1	1123057.P872_19655	3.108e-60	210.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47J9E@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WLSH1_k127_5449968_2	290317.Cpha266_1251	3.498e-49	182.0	COG0513@1|root,COG0513@2|Bacteria,1FDMN@1090|Chlorobi	1090|Chlorobi	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WLSH1_k127_5449968_5	1121912.AUHD01000006_gene1194	4.814e-09	60.0	COG0421@1|root,COG0421@2|Bacteria,4NPK5@976|Bacteroidetes,1I2D9@117743|Flavobacteriia	976|Bacteroidetes	E	Spermidine synthase	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
WLSH1_k127_5449968_4	1137281.D778_02019	7.554e-18	85.0	COG0421@1|root,COG0421@2|Bacteria,4NPK5@976|Bacteroidetes,1I2D9@117743|Flavobacteriia	976|Bacteroidetes	E	Spermidine synthase	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
WLSH1_k127_5451731_0	1121024.AUCD01000039_gene166	2.343e-100	349.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,27F7B@186828|Carnobacteriaceae	91061|Bacilli	S	ABC transporter C-terminal domain	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH1_k127_5453612_1	1471459.JFLJ01000111_gene102	5.353e-47	171.0	COG2805@1|root,COG2805@2|Bacteria,1G0HI@1117|Cyanobacteria,1MKIW@1212|Prochloraceae	1117|Cyanobacteria	NU	Twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH1_k127_5453612_2	1410668.JNKC01000003_gene511	1.501e-08	58.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,36E42@31979|Clostridiaceae	186801|Clostridia	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH1_k127_5453612_0	1047013.AQSP01000118_gene1252	1.298e-119	412.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_545809_0	1906.SFRA_22265	5.303e-09	58.0	COG0739@1|root,COG1652@1|root,COG0739@2|Bacteria,COG1652@2|Bacteria,2GK68@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	ko:K21687	-	-	-	-	ko00000	-	GH23	-	LysM,Peptidase_M23,Transglycosylas
WLSH1_k127_5461400_0	357808.RoseRS_2870	3.155e-48	187.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi,37651@32061|Chloroflexia	32061|Chloroflexia	S	Alpha-2-macroglobulin family	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5
WLSH1_k127_5477586_0	1122947.FR7_0944	1.767e-31	138.0	COG2861@1|root,COG2861@2|Bacteria,1V413@1239|Firmicutes,4H49M@909932|Negativicutes	909932|Negativicutes	S	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
WLSH1_k127_5506855_0	1123371.ATXH01000001_gene1181	1.118e-38	149.0	COG1373@1|root,COG1373@2|Bacteria,2GGZJ@200940|Thermodesulfobacteria	2|Bacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH1_k127_5506855_1	1047013.AQSP01000038_gene1966	7.8e-33	133.0	COG1373@1|root,COG1373@2|Bacteria,2NPXS@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH1_k127_5513586_0	1120985.AUMI01000008_gene2737	1.609e-42	162.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4H2UX@909932|Negativicutes	909932|Negativicutes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
WLSH1_k127_5548897_0	925409.KI911562_gene466	3.485e-22	100.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WLSH1_k127_5632662_0	335541.Swol_2418	8.642e-139	452.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42JIH@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
WLSH1_k127_5632662_1	1121459.AQXE01000001_gene2886	7.391e-58	205.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2M9TD@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH1_k127_5632662_4	459495.SPLC1_S203600	4.926e-14	74.0	COG2173@1|root,COG2173@2|Bacteria,1G07K@1117|Cyanobacteria,1H8T7@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
WLSH1_k127_5632662_3	1173027.Mic7113_1328	1.279e-32	132.0	COG2173@1|root,COG2173@2|Bacteria,1G07K@1117|Cyanobacteria,1H8T7@1150|Oscillatoriales	1117|Cyanobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
WLSH1_k127_5632662_5	391587.KAOT1_08343	1.781e-05	51.0	COG1611@1|root,COG1611@2|Bacteria,4NGWU@976|Bacteroidetes,1I1G2@117743|Flavobacteriia	976|Bacteroidetes	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WLSH1_k127_5632662_2	945713.IALB_1435	1.968e-38	147.0	COG0441@1|root,COG0441@2|Bacteria	2|Bacteria	J	threonyl-tRNA aminoacylation	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WLSH1_k127_5650778_0	525904.Tter_0176	4.329e-99	337.0	COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
WLSH1_k127_5652804_0	644107.SL1157_2843	3.092e-54	199.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,4NB1N@97050|Ruegeria	28211|Alphaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WLSH1_k127_5652804_2	267377.MMP1541	0.0001226	49.0	COG4818@1|root,arCOG04344@2157|Archaea,2XZ6C@28890|Euryarchaeota,23R98@183939|Methanococci	183939|Methanococci	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
WLSH1_k127_5652804_1	698758.AXY_14710	1.131e-10	66.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WLSH1_k127_5670526_1	1007104.SUS17_1864	0.0008835	45.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U8VA@28211|Alphaproteobacteria,2K4TG@204457|Sphingomonadales	204457|Sphingomonadales	NU	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
WLSH1_k127_5670526_0	1423814.HMPREF0549_1745	3.288e-17	85.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,3F6K4@33958|Lactobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WLSH1_k127_5728733_2	1446473.JHWH01000001_gene996	8.056e-08	55.0	COG1739@1|root,COG1739@2|Bacteria,1RHG0@1224|Proteobacteria,2U9IC@28211|Alphaproteobacteria,2PX50@265|Paracoccus	28211|Alphaproteobacteria	S	Uncharacterized protein family UPF0029	-	-	-	-	-	-	-	-	-	-	-	-	UPF0029
WLSH1_k127_5728733_1	263820.PTO1429	3.153e-20	93.0	COG0350@1|root,COG1515@1|root,arCOG00929@2157|Archaea,arCOG02724@2157|Archaea,2XURE@28890|Euryarchaeota,24279@183967|Thermoplasmata	183967|Thermoplasmata	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Endonuclease_5
WLSH1_k127_5728733_0	1120973.AQXL01000128_gene2793	1.176e-101	357.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli,277WB@186823|Alicyclobacillaceae	91061|Bacilli	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WLSH1_k127_5759427_1	485913.Krac_12036	0.0007889	49.0	COG3428@1|root,COG3428@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	PASTA,bPH_2
WLSH1_k127_5759427_0	699246.HMPREF0868_1363	1.42e-46	173.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,26861@186813|unclassified Clostridiales	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
WLSH1_k127_5763465_0	511051.CSE_09400	2.571e-11	67.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
WLSH1_k127_5779450_2	591001.Acfer_1585	0.0006445	51.0	COG3409@1|root,COG3584@1|root,COG3409@2|Bacteria,COG3584@2|Bacteria,1UV4J@1239|Firmicutes,4H4W0@909932|Negativicutes	909932|Negativicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3D,PG_binding_1
WLSH1_k127_5779450_1	1123239.KB898626_gene674	0.0004867	52.0	COG0791@1|root,COG3409@1|root,COG0791@2|Bacteria,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,4ISYS@91061|Bacilli	91061|Bacilli	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,PG_binding_1
WLSH1_k127_5779450_0	1502852.FG94_03618	4.349e-09	67.0	COG2309@1|root,COG2309@2|Bacteria,1R4I5@1224|Proteobacteria,2VPND@28216|Betaproteobacteria,473BI@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_5856266_5	653733.Selin_2521	1.411e-11	69.0	COG1194@1|root,COG1194@2|Bacteria	2|Bacteria	L	base-excision repair	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
WLSH1_k127_5856266_3	1123502.AQXD01000001_gene1033	1.517e-15	79.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,1X4F8@135614|Xanthomonadales	135614|Xanthomonadales	L	glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
WLSH1_k127_5856266_2	357809.Cphy_2835	3.825e-16	88.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,2202G@1506553|Lachnoclostridium	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
WLSH1_k127_5856266_4	411469.EUBHAL_01685	9.713e-15	76.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,25VHS@186806|Eubacteriaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WLSH1_k127_5856266_0	858215.Thexy_1234	4.229e-36	148.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,42ER8@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WLSH1_k127_5856266_1	5762.XP_002679746.1	2.344e-22	101.0	COG0498@1|root,KOG2616@2759|Eukaryota	2759|Eukaryota	E	2-oxobutyrate metabolic process	THNSL1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,SKI,Thr_synth_N
WLSH1_k127_5860253_0	224324.aq_461	2.316e-106	357.0	COG0064@1|root,COG0064@2|Bacteria,2G3P7@200783|Aquificae	200783|Aquificae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WLSH1_k127_5873834_2	940282.CADQ01000100_gene1276	1.809e-26	109.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2TSEQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,FAD_binding_3,Pyr_redox_2
WLSH1_k127_5873834_4	1408436.JHXY01000011_gene1509	2.551e-18	85.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,25UTR@186806|Eubacteriaceae	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
WLSH1_k127_5873834_1	908338.HMPREF9286_1045	3.262e-34	139.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH1_k127_5873834_0	500633.CLOHIR_01232	2.87e-40	159.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,25QPV@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH1_k127_5873834_3	759914.BP951000_1771	2.438e-26	112.0	COG0064@1|root,COG0064@2|Bacteria,2J58X@203691|Spirochaetes	203691|Spirochaetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WLSH1_k127_5900953_0	512565.AMIS_50860	1.173e-42	158.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4D9QG@85008|Micromonosporales	201174|Actinobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WLSH1_k127_5900953_2	1235800.C819_01832	0.0001485	45.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,27I7S@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WLSH1_k127_5900953_1	1121472.AQWN01000004_gene804	1.189e-26	113.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,260QV@186807|Peptococcaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WLSH1_k127_5905163_1	1117319.PSPO_05226	1.814e-09	62.0	COG2501@1|root,COG2501@2|Bacteria,1N8C4@1224|Proteobacteria,1SCIR@1236|Gammaproteobacteria,2Q2CT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	S4 domain	ybcJ	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
WLSH1_k127_5905163_0	485913.Krac_0136	9.559e-38	147.0	COG3451@1|root,COG3451@2|Bacteria	2|Bacteria	U	multi-organism process	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
WLSH1_k127_5908502_1	269799.Gmet_0292	1.059e-05	56.0	COG4412@1|root,COG4932@1|root,COG4412@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_5908502_0	1304888.ATWF01000002_gene59	6.682e-08	60.0	COG1404@1|root,COG5184@1|root,COG1404@2|Bacteria,COG5184@2|Bacteria,2GGNW@200930|Deferribacteres	200930|Deferribacteres	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH1_k127_5908502_2	371731.Rsw2DRAFT_0690	8.125e-05	51.0	COG2931@1|root,COG5295@1|root,COG2931@2|Bacteria,COG5295@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,1FCAX@1060|Rhodobacter	28211|Alphaproteobacteria	Q	Hint domain	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Hint_2
WLSH1_k127_5915606_1	457421.CBFG_05810	0.0002709	52.0	2CFJX@1|root,33270@2|Bacteria,1VG2G@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_5915606_0	1121333.JMLH01000078_gene2853	3.916e-05	48.0	COG1141@1|root,COG1141@2|Bacteria,1VKNJ@1239|Firmicutes,3VRZN@526524|Erysipelotrichia	526524|Erysipelotrichia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
WLSH1_k127_5947915_0	1313421.JHBV01000041_gene3530	5.678e-07	57.0	COG4642@1|root,COG4642@2|Bacteria	2|Bacteria	S	regulation of ryanodine-sensitive calcium-release channel activity	-	-	-	-	-	-	-	-	-	-	-	-	MORN
WLSH1_k127_5954809_2	426368.MmarC7_0341	7.747e-15	80.0	COG2244@1|root,arCOG02209@2157|Archaea,2XVVS@28890|Euryarchaeota,23Q3M@183939|Methanococci	183939|Methanococci	S	Polysaccharide biosynthesis protein	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WLSH1_k127_5954809_1	1123009.AUID01000020_gene145	1.117e-62	224.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,268V0@186813|unclassified Clostridiales	186801|Clostridia	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WLSH1_k127_5954809_0	1460635.JCM19038_3879	2.641e-98	330.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli	91061|Bacilli	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WLSH1_k127_5975956_0	643648.Slip_1000	1.594e-16	84.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,42JPV@68298|Syntrophomonadaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WLSH1_k127_599178_6	484770.UFO1_2245	0.0003498	50.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	gspG	-	-	ko:K02456,ko:K02650,ko:K02655	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl,T2SSG
WLSH1_k127_599178_4	224324.aq_633	1.376e-09	63.0	COG0272@1|root,COG0272@2|Bacteria,2G3NB@200783|Aquificae	200783|Aquificae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH1_k127_599178_2	762903.Pedsa_0152	1.038e-15	78.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,1IQAI@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH1_k127_599178_1	537972.ABQU01000065_gene1438	1.394e-21	96.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2YM83@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH1_k127_599178_0	290633.GOX0168	2.672e-33	132.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,2JQB4@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
WLSH1_k127_599178_3	1515613.HQ37_08300	2.756e-10	63.0	COG0272@1|root,COG0272@2|Bacteria,4NE2X@976|Bacteroidetes,2FKZZ@200643|Bacteroidia,22WHC@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH1_k127_599178_5	525282.HMPREF0391_11305	5.201e-07	52.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,22G1U@1570339|Peptoniphilaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH1_k127_5996232_1	1246.JMEA01000005_gene1250	3.798e-13	70.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli,4AWS7@81850|Leuconostocaceae	91061|Bacilli	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WLSH1_k127_5996232_0	1122176.KB903587_gene4426	3.001e-14	83.0	COG0659@1|root,COG0659@2|Bacteria,4NFX2@976|Bacteroidetes,1IW25@117747|Sphingobacteriia	976|Bacteroidetes	P	COG0659 Sulfate permease and related	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WLSH1_k127_5996232_2	5888.CAK93203	2.353e-07	59.0	COG0659@1|root,2T2NQ@2759|Eukaryota,3ZFFC@5878|Ciliophora	5878|Ciliophora	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfate_transp
WLSH1_k127_6002811_0	515635.Dtur_0873	1.113e-81	279.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	ctsE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH1_k127_6064479_1	176090.SSIN_1607	2.156e-29	117.0	COG0561@1|root,COG0652@1|root,COG0561@2|Bacteria,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli	91061|Bacilli	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Hydrolase_3,Pro_isomerase
WLSH1_k127_6064479_2	1229758.C270_05940	4.151e-21	94.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli,4AX50@81850|Leuconostocaceae	91061|Bacilli	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Hydrolase_3,Pro_isomerase
WLSH1_k127_6064479_0	28532.XP_010558607.1	9.527e-65	224.0	COG0525@1|root,KOG0432@2759|Eukaryota,37QE7@33090|Viridiplantae,3GBVU@35493|Streptophyta,3HP0S@3699|Brassicales	35493|Streptophyta	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061458,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WLSH1_k127_6113885_0	880526.KE386488_gene209	4.099e-12	75.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia,22UD9@171550|Rikenellaceae	976|Bacteroidetes	S	von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
WLSH1_k127_6133201_0	1227497.C491_06643	1.131e-10	74.0	COG1199@1|root,arCOG00770@2157|Archaea,2XSWZ@28890|Euryarchaeota,23S1B@183963|Halobacteria	183963|Halobacteria	K	COG1199 Rad3-related DNA helicases	-	-	-	-	-	-	-	-	-	-	-	-	DEAD_2,Helicase_C_2
WLSH1_k127_6156300_0	309801.trd_0832	5.806e-98	327.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi,27XPX@189775|Thermomicrobia	189775|Thermomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WLSH1_k127_6180469_0	469618.FVAG_00910	1.3e-20	92.0	COG0714@1|root,COG0714@2|Bacteria,379JE@32066|Fusobacteria	32066|Fusobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH1_k127_6180469_1	1112216.JH594425_gene2134	2.259e-05	49.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,2K1NZ@204457|Sphingomonadales	204457|Sphingomonadales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH1_k127_6215789_5	1379858.N508_01794	2.196e-22	99.0	COG0769@1|root,COG0769@2|Bacteria,2GEVK@200930|Deferribacteres	200930|Deferribacteres	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH1_k127_6215789_1	1380408.AVGH01000039_gene2250	3.336e-46	175.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,21WCG@150247|Anoxybacillus	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH1_k127_6215789_0	1449050.JNLE01000005_gene5206	8.025e-117	387.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,36DX4@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	-	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WLSH1_k127_6215789_6	264201.pc1228	1.019e-16	85.0	COG1190@1|root,COG1190@2|Bacteria,2JFIC@204428|Chlamydiae	204428|Chlamydiae	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WLSH1_k127_6215789_4	1140.Synpcc7942_1340	5.799e-27	116.0	COG0242@1|root,COG0242@2|Bacteria,1G1FB@1117|Cyanobacteria,1GZM4@1129|Synechococcus	1117|Cyanobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WLSH1_k127_6215789_7	1121899.Q764_05005	4.47e-12	67.0	COG0692@1|root,COG0692@2|Bacteria,4NE2B@976|Bacteroidetes,1HY4H@117743|Flavobacteriia,2P070@237|Flavobacterium	976|Bacteroidetes	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH1_k127_6215789_3	1349767.GJA_5456	1.786e-27	111.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2VHN3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH1_k127_6215789_8	1497679.EP56_03140	1.392e-08	55.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HG5F@91061|Bacilli,26M61@186820|Listeriaceae	91061|Bacilli	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH1_k127_6215789_2	1198452.Jab_1c01850	2.191e-32	126.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2VHN3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH1_k127_6243637_1	323259.Mhun_0005	1.003e-05	50.0	COG0642@1|root,COG2202@1|root,arCOG02330@1|root,arCOG02377@1|root,arCOG02330@2157|Archaea,arCOG02377@2157|Archaea,arCOG06192@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,PocR,Response_reg
WLSH1_k127_6243637_0	582402.Hbal_1992	1.017e-14	76.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,43WMM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
WLSH1_k127_6248835_1	1280696.ATVY01000009_gene3088	1.112e-22	98.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,4BXTC@830|Butyrivibrio	186801|Clostridia	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH1_k127_6248835_0	596324.TREVI0001_2195	5.118e-124	404.0	COG0495@1|root,COG0495@2|Bacteria,2J5BV@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH1_k127_6248835_2	545694.TREPR_3229	2.88e-21	97.0	COG0495@1|root,COG0495@2|Bacteria,2J5BV@203691|Spirochaetes	203691|Spirochaetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH1_k127_6255965_0	479434.Sthe_1164	2.129e-21	98.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,27YGT@189775|Thermomicrobia	189775|Thermomicrobia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
WLSH1_k127_6255965_1	1280689.AUJC01000008_gene2936	1.602e-16	88.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,36EZJ@31979|Clostridiaceae	186801|Clostridia	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH1_k127_6305855_0	3067.XP_002953335.1	0.0002146	51.0	KOG3509@1|root,KOG3509@2759|Eukaryota	2759|Eukaryota	S	calcium ion binding	SSPO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.11.1.7	ko:K19511	-	-	-	-	ko00000,ko01000	-	-	-	C8,F5_F8_type_C,Ig_3,Kazal_2,LRR_8,Ldl_recept_a,TIL,TSP_1,VWC,VWD
WLSH1_k127_6344873_0	595537.Varpa_0977	1.221e-14	76.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,4AAXV@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH1_k127_6344873_1	1267535.KB906767_gene1214	2.03e-13	76.0	COG2433@1|root,COG2433@2|Bacteria,3Y7F1@57723|Acidobacteria	57723|Acidobacteria	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
WLSH1_k127_6356832_0	1158318.ATXC01000001_gene640	9.683e-15	81.0	COG4902@1|root,COG4902@2|Bacteria	2|Bacteria	-	-	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	DUF2202
WLSH1_k127_6387640_1	273121.WS0696	1.485e-57	217.0	COG3829@1|root,COG3829@2|Bacteria,1RH32@1224|Proteobacteria,42RBS@68525|delta/epsilon subdivisions,2YP0S@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	KT	sensor protein	cetB	-	-	-	-	-	-	-	-	-	-	-	PAS,PAS_3
WLSH1_k127_6387640_5	5722.XP_001582263.1	5.945e-06	49.0	COG0666@1|root,KOG4177@2759|Eukaryota,KOG4412@2759|Eukaryota	2759|Eukaryota	L	proteasome regulatory particle assembly	-	-	-	ko:K15503,ko:K15504	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
WLSH1_k127_6387640_4	5722.XP_001318041.1	3.692e-08	57.0	COG0666@1|root,KOG0504@2759|Eukaryota	2759|Eukaryota	I	protein ubiquitination	-	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
WLSH1_k127_6387640_0	868864.Dester_0256	6.582e-174	576.0	COG0209@1|root,COG0209@2|Bacteria,2G3TE@200783|Aquificae	200783|Aquificae	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
WLSH1_k127_6387640_3	8153.XP_005929556.1	2.775e-17	88.0	KOG3128@1|root,KOG3128@2759|Eukaryota,39AX7@33154|Opisthokonta,3BGKK@33208|Metazoa,3CYGM@33213|Bilateria,482AP@7711|Chordata,495DP@7742|Vertebrata,49V44@7898|Actinopterygii	33208|Metazoa	S	5'-nucleotidase, cytosolic IIIA	NT5C3A	GO:0000215,GO:0000287,GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009123,GO:0009125,GO:0009158,GO:0009161,GO:0009164,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0012505,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042578,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046128,GO:0046130,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:0098542,GO:0140098,GO:0140101,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	UMPH-1
WLSH1_k127_6387640_6	13616.ENSMODP00000018406	0.0001123	48.0	KOG3128@1|root,KOG3128@2759|Eukaryota,39AX7@33154|Opisthokonta,3BGKK@33208|Metazoa,3D2VG@33213|Bilateria,4863A@7711|Chordata,4971B@7742|Vertebrata,3JBX4@40674|Mammalia,4JWIT@9263|Metatheria	33208|Metazoa	F	5'-nucleotidase, cytosolic IIIB	NT5C3B	GO:0000288,GO:0000291,GO:0000956,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006401,GO:0006402,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009057,GO:0009058,GO:0009116,GO:0009119,GO:0009123,GO:0009125,GO:0009158,GO:0009161,GO:0009164,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042578,GO:0043170,GO:0043928,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072521,GO:0072523,GO:0090304,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	UMPH-1
WLSH1_k127_6387640_2	269799.Gmet_0175	6.411e-53	196.0	COG0791@1|root,COG0791@2|Bacteria,1NRCV@1224|Proteobacteria,42YTE@68525|delta/epsilon subdivisions,2WUEN@28221|Deltaproteobacteria,43U28@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_6388423_3	227941.CCA_00128	0.0002962	43.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2JFW6@204428|Chlamydiae	204428|Chlamydiae	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WLSH1_k127_6388423_0	552811.Dehly_0095	6.683e-39	149.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,34CQM@301297|Dehalococcoidia	301297|Dehalococcoidia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WLSH1_k127_6388423_1	189426.PODO_09510	6.375e-37	143.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli,26QXQ@186822|Paenibacillaceae	91061|Bacilli	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
WLSH1_k127_6388423_2	1008459.TASI_1128	3.169e-13	76.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,3T32Z@506|Alcaligenaceae	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WLSH1_k127_6396715_3	479434.Sthe_1068	5.384e-06	49.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi,27YEC@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WLSH1_k127_6396715_1	1286171.EAL2_c01920	3.196e-40	153.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,25WEH@186806|Eubacteriaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WLSH1_k127_6396715_2	608506.COB47_0868	1.724e-16	83.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,42GJW@68295|Thermoanaerobacterales	186801|Clostridia	J	ribosomal protein l17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WLSH1_k127_6396715_0	748449.Halha_0216	3.823e-61	222.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WAFV@53433|Halanaerobiales	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WLSH1_k127_6404405_0	416591.Tlet_0786	1.736e-56	201.0	COG0192@1|root,COG0192@2|Bacteria,2GCFC@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WLSH1_k127_6404405_1	398512.JQKC01000007_gene1057	4.591e-10	67.0	28I50@1|root,2Z88F@2|Bacteria,1V10M@1239|Firmicutes,24I2A@186801|Clostridia,3WPAD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_6430787_2	1432050.IE4771_CH02254	1.37e-23	104.0	COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2VFZS@28211|Alphaproteobacteria,4BMHX@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Integral membrane protein TerC family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TerC
WLSH1_k127_6430787_1	1348635.BBJY01000005_gene3257	2.136e-57	217.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1NAY1@1224|Proteobacteria,1RP74@1236|Gammaproteobacteria,1XSE4@135623|Vibrionales	135623|Vibrionales	J	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA	rsmF	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.178	ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA
WLSH1_k127_6430787_3	1444712.BN1013_01468	3.428e-19	91.0	COG0234@1|root,COG0234@2|Bacteria,2JG6X@204428|Chlamydiae	204428|Chlamydiae	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WLSH1_k127_6430787_0	926569.ANT_26670	1.745e-166	535.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WLSH1_k127_6435628_0	1340493.JNIF01000003_gene1736	2.54e-101	337.0	COG0016@1|root,COG0016@2|Bacteria,3Y3NJ@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WLSH1_k127_6441761_0	1408433.JHXV01000016_gene1847	4.42e-09	66.0	COG1708@1|root,COG1708@2|Bacteria,4NPRU@976|Bacteroidetes,1I105@117743|Flavobacteriia	976|Bacteroidetes	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH1_k127_6465418_4	1033738.CAEP01000260_gene3577	3.363e-06	50.0	2ETWR@1|root,33MDY@2|Bacteria,1VQ84@1239|Firmicutes,4HSAH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_6465418_1	138119.DSY3166	6.474e-20	93.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,262DA@186807|Peptococcaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WLSH1_k127_6465418_2	891968.Anamo_1519	4.611e-13	78.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,3T9T4@508458|Synergistetes	508458|Synergistetes	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
WLSH1_k127_6465418_5	1232430.CAVG010000071_gene698	0.0005623	44.0	COG0741@1|root,COG3942@1|root,COG0741@2|Bacteria,COG3942@2|Bacteria,1UNUC@1239|Firmicutes,4IUPT@91061|Bacilli,4H1RP@90964|Staphylococcaceae	91061|Bacilli	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Peptidase_M23
WLSH1_k127_6465418_0	755178.Cyan10605_1695	1.293e-48	182.0	COG0042@1|root,COG0042@2|Bacteria,1G0PN@1117|Cyanobacteria	1117|Cyanobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
WLSH1_k127_6465418_3	926561.KB900621_gene2861	1.084e-12	72.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3WAGN@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
WLSH1_k127_6551118_1	411490.ANACAC_02006	1.088e-65	229.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
WLSH1_k127_6551118_2	1158294.JOMI01000007_gene212	3.481e-33	130.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,2FMZT@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
WLSH1_k127_6551118_3	743719.PaelaDRAFT_1543	2.167e-11	68.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,26QET@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
WLSH1_k127_6551118_4	1408473.JHXO01000013_gene536	1.267e-06	53.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes,2FMZT@200643|Bacteroidia	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
WLSH1_k127_6551118_0	745411.B3C1_08676	6.567e-82	287.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1J4C1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	histidyl-tRNA synthetase	hisS	GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iE2348C_1286.E2348C_2797,iECNA114_1301.ECNA114_2592,iECSF_1327.ECSF_2358	HGTP_anticodon,tRNA-synt_His
WLSH1_k127_6558968_0	321327.CYA_2346	5.707e-109	363.0	COG0021@1|root,COG0021@2|Bacteria,1G0GC@1117|Cyanobacteria,1GZ7M@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WLSH1_k127_6604319_3	862965.PARA_08510	1.22e-05	50.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1Y7GR@135625|Pasteurellales	135625|Pasteurellales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WLSH1_k127_6604319_0	246194.CHY_0259	1.834e-104	343.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,42EYE@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH1_k127_6604319_2	1280686.AUKE01000001_gene2167	2.594e-26	110.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,4BX9D@830|Butyrivibrio	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH1_k127_6604319_1	1449335.JQLG01000004_gene1442	8.599e-53	188.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli,27F9T@186828|Carnobacteriaceae	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH1_k127_6609571_0	709032.Sulku_1491	1.004e-114	374.0	COG0643@1|root,COG0643@2|Bacteria,1R7CN@1224|Proteobacteria,42PXU@68525|delta/epsilon subdivisions,2YNWD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c
WLSH1_k127_6609571_1	709032.Sulku_1490	1.221e-68	236.0	COG1406@1|root,COG1406@2|Bacteria,1NFHA@1224|Proteobacteria,42WKA@68525|delta/epsilon subdivisions,2YSDX@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	N	Chemotaxis phosphatase CheX	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
WLSH1_k127_6609571_2	709032.Sulku_1489	4.088e-08	55.0	COG2201@1|root,COG2201@2|Bacteria,1QZ2G@1224|Proteobacteria,43CEJ@68525|delta/epsilon subdivisions,2YQ1P@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WLSH1_k127_6639608_0	330214.NIDE3436	4.934e-05	54.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE3436|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_6663224_0	1403819.BATR01000094_gene2946	2.006e-44	173.0	COG0072@1|root,COG0072@2|Bacteria,46SDG@74201|Verrucomicrobia,2ITHP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WLSH1_k127_6702881_0	1353529.M899_1215	1.221e-108	361.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2MSMW@213481|Bdellovibrionales,2WJ3E@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH1_k127_6702881_1	264462.Bd3872	7.515e-27	110.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2MTIB@213481|Bdellovibrionales,2WJV2@28221|Deltaproteobacteria	213481|Bdellovibrionales	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
WLSH1_k127_6702881_3	224719.Abm4_1618	0.0001414	46.0	arCOG06880@1|root,arCOG06880@2157|Archaea,2Y864@28890|Euryarchaeota	28890|Euryarchaeota	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH1_k127_6702881_2	290317.Cpha266_1411	1.812e-23	102.0	COG0566@1|root,COG0566@2|Bacteria,1FDZH@1090|Chlorobi	1090|Chlorobi	H	PFAM tRNA rRNA methyltransferase (SpoU)	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
WLSH1_k127_6755979_0	1507.HMPREF0262_01111	2.519e-82	280.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,36EAY@31979|Clostridiaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
WLSH1_k127_6755979_1	945713.IALB_2599	2.401e-16	80.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH1_k127_6784394_0	521097.Coch_0390	7.837e-54	199.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,1IIKD@117743|Flavobacteriia,1ERG6@1016|Capnocytophaga	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH1_k127_6784394_1	96561.Dole_3114	5.589e-15	76.0	COG0463@1|root,COG0463@2|Bacteria,1QW1R@1224|Proteobacteria,42R1R@68525|delta/epsilon subdivisions,2X72M@28221|Deltaproteobacteria,2MNMW@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WLSH1_k127_6805620_0	1489678.RDMS_09110	7.049e-76	267.0	COG0593@1|root,COG0593@2|Bacteria,1WIHX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WLSH1_k127_6805620_1	1408415.JHXL01000008_gene185	3.488e-12	68.0	COG0593@1|root,COG0593@2|Bacteria,3WT3A@544448|Tenericutes	544448|Tenericutes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WLSH1_k127_6820704_0	1165096.ARWF01000001_gene219	2.277e-13	73.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,2KMRX@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WLSH1_k127_6824706_0	103733.JNYO01000056_gene1095	1.839e-38	151.0	COG1216@1|root,COG1216@2|Bacteria,2I2J1@201174|Actinobacteria,4EDQ0@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH1_k127_6824706_1	1392493.JIAB01000001_gene1746	3.689e-27	118.0	COG1215@1|root,COG1215@2|Bacteria,1UIBE@1239|Firmicutes,25EGF@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH1_k127_6857687_0	15368.BRADI1G43020.1	2.954e-71	253.0	COG2801@1|root,KOG0017@2759|Eukaryota,37THH@33090|Viridiplantae,3GG2K@35493|Streptophyta,3M2IR@4447|Liliopsida,3IKX9@38820|Poales	35493|Streptophyta	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_2,gag_pre-integrs,rve
WLSH1_k127_6858887_0	338966.Ppro_2445	0.0006108	48.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2,CHU_C,Copper-bind,DUF1080,DUF11
WLSH1_k127_6876163_1	1296415.JACC01000023_gene4307	3.901e-05	51.0	COG0438@1|root,COG0438@2|Bacteria,4NETA@976|Bacteroidetes,1HZ9Z@117743|Flavobacteriia,2YHJW@290174|Aquimarina	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH1_k127_6876163_0	573569.F7308_1118	1.331e-18	93.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria,4612P@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyl transferases group 1	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WLSH1_k127_6899057_2	289397.MBOVPG45_0594	1.594e-44	171.0	COG0130@1|root,COG0130@2|Bacteria,3WTAQ@544448|Tenericutes	544448|Tenericutes	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
WLSH1_k127_6899057_5	1128421.JAGA01000002_gene636	4.797e-13	76.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	XK27_09705	-	6.1.1.14	ko:K01879,ko:K06950	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HD
WLSH1_k127_6899057_3	443152.MDG893_11701	3.441e-20	101.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,464B8@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Belongs to the peptidase S26 family	lepB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
WLSH1_k127_6899057_4	1175306.GWL_44920	6.331e-16	82.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,472M3@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WLSH1_k127_6899057_0	1444309.JAQG01000038_gene2820	8.922e-162	526.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,26TFI@186822|Paenibacillaceae	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WLSH1_k127_6899057_1	272134.KB731324_gene5568	3.128e-50	186.0	COG0653@1|root,COG0653@2|Bacteria,1G1B4@1117|Cyanobacteria,1H8K0@1150|Oscillatoriales	1117|Cyanobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
WLSH1_k127_690049_2	387093.SUN_2065	1.986e-13	71.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2YMF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	ATP-dependent CLP protease ATP-binding subunit	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WLSH1_k127_690049_0	697284.ERIC2_c38800	9.36e-77	264.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,26RRK@186822|Paenibacillaceae	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WLSH1_k127_690049_1	1392501.JIAC01000001_gene453	5.013e-17	81.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H206@909932|Negativicutes	909932|Negativicutes	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WLSH1_k127_6931531_1	768704.Desmer_4028	3.818e-05	53.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,260KF@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WLSH1_k127_6931531_0	269797.Mbar_A1941	3.103e-13	76.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota,2NB2Q@224756|Methanomicrobia	224756|Methanomicrobia	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WLSH1_k127_6931531_2	410358.Mlab_0477	0.0001187	48.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota	28890|Euryarchaeota	O	Peptidyl-prolyl cis-trans	mtfK1	-	5.2.1.8	ko:K01802,ko:K03768,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WLSH1_k127_694528_0	861454.HMPREF9099_00258	4.926e-14	74.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,27IWZ@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WLSH1_k127_694528_1	1394178.AWOO02000011_gene3932	0.0003618	51.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,4EIK2@85012|Streptosporangiales	201174|Actinobacteria	M	Sortase family	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
WLSH1_k127_6953054_6	670487.Ocepr_2127	2.015e-06	55.0	COG0739@1|root,COG0739@2|Bacteria,1WIMC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH1_k127_6953054_1	1449063.JMLS01000012_gene5532	5.406e-60	213.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli,26SES@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WLSH1_k127_6953054_4	641149.HMPREF9016_00670	1.483e-10	63.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,2KPM8@206351|Neisseriales	206351|Neisseriales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WLSH1_k127_6953054_2	592029.DDD_0030	4.549e-21	95.0	COG0482@1|root,COG0482@2|Bacteria,4NFXZ@976|Bacteroidetes,1HWQ1@117743|Flavobacteriia,3HK3A@363408|Nonlabens	976|Bacteroidetes	J	tRNA methyl transferase	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WLSH1_k127_6953054_5	208960.XP_007265813.1	8.343e-08	59.0	28N75@1|root,2QUSF@2759|Eukaryota,3A77U@33154|Opisthokonta,3P5YA@4751|Fungi,3V211@5204|Basidiomycota,22EKF@155619|Agaricomycetes	4751|Fungi	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,NT5C
WLSH1_k127_6953054_0	118166.JH976537_gene3093	1.852e-64	228.0	COG1131@1|root,COG1131@2|Bacteria,1G0UC@1117|Cyanobacteria,1H9JW@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH1_k127_6953054_3	938293.CAJU020000009_gene1266	2.488e-11	66.0	COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,24A31@186801|Clostridia,22G2M@1570339|Peptoniphilaceae	186801|Clostridia	O	cog cog0450	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
WLSH1_k127_6956109_0	1034943.BN1094_02363	5.197e-12	76.0	COG3868@1|root,COG3868@2|Bacteria,1MXYK@1224|Proteobacteria,1RMK1@1236|Gammaproteobacteria,1JFSD@118969|Legionellales	118969|Legionellales	S	Glycoside-hydrolase family GH114	-	-	-	ko:K21006	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_114
WLSH1_k127_6957421_0	1162668.LFE_1113	1e-13	79.0	COG3391@1|root,COG3391@2|Bacteria,3J19W@40117|Nitrospirae	40117|Nitrospirae	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
WLSH1_k127_6998509_0	928724.SacglDRAFT_02623	4.933e-06	49.0	COG2133@1|root,COG3291@1|root,COG3828@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GMT2@201174|Actinobacteria,4E9PV@85010|Pseudonocardiales	201174|Actinobacteria	G	PFAM F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,F5_F8_type_C,GSDH,PKD,ThuA
WLSH1_k127_7008791_0	1131813.AQVT01000001_gene1639	5.123e-09	65.0	COG3335@1|root,COG3335@2|Bacteria,1P76X@1224|Proteobacteria,2UGCZ@28211|Alphaproteobacteria,1JTGI@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
WLSH1_k127_7021425_1	709991.Odosp_0764	1.99e-30	129.0	COG0847@1|root,COG0847@2|Bacteria,4NP7B@976|Bacteroidetes,2FSMF@200643|Bacteroidia,22Y26@171551|Porphyromonadaceae	976|Bacteroidetes	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
WLSH1_k127_7021425_0	1294142.CINTURNW_0968	6.22e-49	180.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,36E5A@31979|Clostridiaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH1_k127_7021425_2	4155.Migut.D01199.1.p	1.575e-22	101.0	COG0484@1|root,KOG0715@2759|Eukaryota,37M6Z@33090|Viridiplantae,3GBY2@35493|Streptophyta,44EJ4@71274|asterids	35493|Streptophyta	O	Chaperone protein DNAj	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH1_k127_7021425_3	1219084.AP014508_gene1136	0.0003276	44.0	COG0484@1|root,COG0484@2|Bacteria,2GC14@200918|Thermotogae	200918|Thermotogae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH1_k127_7030334_1	714961.BFZC1_22634	1.827e-14	85.0	COG0739@1|root,COG1388@1|root,COG3583@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,4HB43@91061|Bacilli,3IXJZ@400634|Lysinibacillus	91061|Bacilli	M	membrane	nlpD	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
WLSH1_k127_7030334_0	1121423.JONT01000007_gene497	5.776e-16	90.0	COG2247@1|root,COG5492@1|root,COG2247@2|Bacteria,COG5492@2|Bacteria,1UJJ9@1239|Firmicutes,25F4A@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,SLH
WLSH1_k127_7037338_1	580332.Slit_2604	9.319e-33	131.0	COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,2WB4G@28216|Betaproteobacteria,44WNY@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Pfam:N_methyl_2	-	-	-	ko:K10924	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
WLSH1_k127_7037338_0	935836.JAEL01000022_gene1624	4.605e-33	137.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,1ZBA5@1386|Bacillus	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WLSH1_k127_7037338_5	1033737.CAEV01000010_gene2448	4.605e-09	60.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,36E84@31979|Clostridiaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WLSH1_k127_7037338_3	588581.Cpap_3278	3.743e-14	79.0	COG2211@1|root,COG2211@2|Bacteria,1UKKD@1239|Firmicutes,25GE3@186801|Clostridia	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH1_k127_7037338_2	862517.HMPREF9225_1023	4.407e-22	101.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,22HPP@1570339|Peptoniphilaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
WLSH1_k127_7037338_6	745310.G432_11080	2.409e-05	48.0	2CFS3@1|root,32S2D@2|Bacteria,1N23S@1224|Proteobacteria,2U9XJ@28211|Alphaproteobacteria,2K236@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_7037338_4	1280685.AUKC01000028_gene663	1.539e-13	71.0	2DN9Q@1|root,32WAD@2|Bacteria,1VRWI@1239|Firmicutes,24ZBK@186801|Clostridia,4BWQI@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_7063764_0	195522.BD01_1489	6.68e-09	68.0	COG2244@1|root,arCOG02209@2157|Archaea,2XSUR@28890|Euryarchaeota,245B4@183968|Thermococci	183968|Thermococci	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WLSH1_k127_7063764_1	386456.JQKN01000005_gene507	7.211e-05	49.0	COG2244@1|root,arCOG02209@2157|Archaea,2XSUR@28890|Euryarchaeota	28890|Euryarchaeota	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WLSH1_k127_7081881_0	484770.UFO1_3117	6.783e-36	141.0	COG1051@1|root,COG1051@2|Bacteria,1V7E6@1239|Firmicutes,4H4XZ@909932|Negativicutes	909932|Negativicutes	F	Hydrolase, NUDIX family	-	-	3.6.1.55,3.6.1.56	ko:K03574,ko:K17816	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WLSH1_k127_7081881_1	1238184.CM001792_gene385	2.243e-32	133.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9ZK@91061|Bacilli,23K45@182709|Oceanobacillus	91061|Bacilli	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WLSH1_k127_7081881_2	1122149.BACN01000027_gene1528	7.335e-28	119.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WLSH1_k127_7081881_3	1545701.LACWKB10_1322	1.357e-18	88.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,3F3QI@33958|Lactobacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH1_k127_7081881_4	768706.Desor_4294	3.135e-08	55.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,263T6@186807|Peptococcaceae	186801|Clostridia	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH1_k127_7143065_0	196490.AUEZ01000016_gene3160	1.271e-08	63.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,3JQS3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	CHASE2	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WLSH1_k127_7143065_1	1449063.JMLS01000002_gene1135	6.032e-06	54.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1UYB2@1239|Firmicutes,4HIMD@91061|Bacilli,26TDP@186822|Paenibacillaceae	91061|Bacilli	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WLSH1_k127_7175848_0	5762.XP_002672387.1	6.046e-14	84.0	2EME7@1|root,2SR3F@2759|Eukaryota	5762.XP_002672387.1|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_7209211_0	1296416.JACB01000010_gene1521	6.746e-30	124.0	COG2834@1|root,COG3391@1|root,COG2834@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,1I9S0@117743|Flavobacteriia	976|Bacteroidetes	M	Cadherin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,NHL
WLSH1_k127_7209211_2	1396418.BATQ01000020_gene5037	0.000316	44.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,2IUGQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WLSH1_k127_7209211_1	1415775.U729_1656	1.461e-10	66.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,36IPK@31979|Clostridiaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
WLSH1_k127_7211126_1	1336803.PHEL49_2113	0.000539	43.0	COG2273@1|root,COG3209@1|root,COG3637@1|root,COG4625@1|root,COG2273@2|Bacteria,COG3209@2|Bacteria,COG3637@2|Bacteria,COG4625@2|Bacteria,4PKBQ@976|Bacteroidetes,1IJ7S@117743|Flavobacteriia	976|Bacteroidetes	M	SPTR CHU large protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF5011,HYR,SprB
WLSH1_k127_7211126_0	1122138.AQUZ01000041_gene7287	1.985e-06	59.0	COG2373@1|root,COG2373@2|Bacteria,2GPUR@201174|Actinobacteria	201174|Actinobacteria	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_7215386_4	215803.DB30_7231	5.415e-10	61.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,42M2Y@68525|delta/epsilon subdivisions,2WKJG@28221|Deltaproteobacteria,2YUCJ@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
WLSH1_k127_7215386_1	714943.Mucpa_0634	1.367e-34	136.0	COG0702@1|root,COG0702@2|Bacteria,4NE40@976|Bacteroidetes,1IRWC@117747|Sphingobacteriia	976|Bacteroidetes	GM	NmrA family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
WLSH1_k127_7215386_2	866536.Belba_1037	2.765e-20	93.0	COG0702@1|root,COG0702@2|Bacteria,4NE40@976|Bacteroidetes,47XJX@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
WLSH1_k127_7215386_3	857290.HMPREF9156_01054	1.12e-15	78.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4CZ2I@85004|Bifidobacteriales	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH1_k127_7215386_5	762968.HMPREF9441_02853	2.746e-08	56.0	COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia	976|Bacteroidetes	S	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH1_k127_7215386_0	1131269.AQVV01000007_gene1015	1.338e-37	142.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH1_k127_7244287_0	1392493.JIAB01000001_gene1532	1.589e-27	119.0	COG0745@1|root,COG0745@2|Bacteria,1V1RY@1239|Firmicutes,25B9C@186801|Clostridia,27KVZ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_7244287_1	768670.Calni_1202	2.919e-20	98.0	COG0745@1|root,COG0745@2|Bacteria,2GFS3@200930|Deferribacteres	200930|Deferribacteres	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH1_k127_7244287_3	622312.ROSEINA2194_00244	1.602e-06	51.0	COG0642@1|root,COG2205@2|Bacteria,1V1U7@1239|Firmicutes,24GNQ@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WLSH1_k127_7244287_2	118173.KB235914_gene197	4.838e-07	58.0	COG0642@1|root,COG2205@2|Bacteria,1G2I4@1117|Cyanobacteria,1H7VC@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
WLSH1_k127_7267043_1	926559.JoomaDRAFT_0279	1.389e-43	159.0	COG0188@1|root,COG0188@2|Bacteria,4NDWQ@976|Bacteroidetes,1HY4P@117743|Flavobacteriia	976|Bacteroidetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH1_k127_7267043_0	880073.Calab_0944	5.606e-127	410.0	COG0187@1|root,COG0187@2|Bacteria,2NNSN@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WLSH1_k127_7270091_0	309799.DICTH_1273	1.82e-89	310.0	COG0172@1|root,COG0172@2|Bacteria	2|Bacteria	J	seryl-tRNA aminoacylation	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WLSH1_k127_7270091_1	1385517.N800_08775	6.351e-19	92.0	COG2871@1|root,COG3182@1|root,COG2871@2|Bacteria,COG3182@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,1X6HX@135614|Xanthomonadales	135614|Xanthomonadales	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1,PepSY_TM
WLSH1_k127_7284315_0	517418.Ctha_1137	3.801e-38	151.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
WLSH1_k127_7284315_1	880073.Calab_0181	8.154e-13	76.0	COG2067@1|root,COG2067@2|Bacteria,2NRFG@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_7291860_1	1191523.MROS_2818	3.431e-15	82.0	2DTQV@1|root,33MB6@2|Bacteria	2|Bacteria	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
WLSH1_k127_7291860_0	517418.Ctha_2424	1.021e-21	101.0	COG0768@1|root,COG0768@2|Bacteria,1FD7D@1090|Chlorobi	1090|Chlorobi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WLSH1_k127_7322692_1	1123325.JHUV01000009_gene431	3.237e-63	224.0	COG0149@1|root,COG0149@2|Bacteria,2G4FH@200783|Aquificae	200783|Aquificae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WLSH1_k127_7322692_0	1004149.AFOE01000004_gene2414	4.674e-123	408.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1HXNG@117743|Flavobacteriia	976|Bacteroidetes	C	Aldehyde dehydrogenase	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79	ko:K00128,ko:K00135	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00350,ko00380,ko00410,ko00561,ko00620,ko00625,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00350,map00380,map00410,map00561,map00620,map00625,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135	R00264,R00631,R00710,R00713,R00714,R00904,R01752,R01986,R02401,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH1_k127_7330705_0	388413.ALPR1_03310	3.072e-145	461.0	COG0175@1|root,COG0175@2|Bacteria,4NEPD@976|Bacteroidetes,47JCC@768503|Cytophagia	976|Bacteroidetes	EH	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
WLSH1_k127_7330705_1	1120966.AUBU01000008_gene2603	1.302e-46	169.0	COG2895@1|root,COG2895@2|Bacteria,4NETI@976|Bacteroidetes,47KGK@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU
WLSH1_k127_7339322_1	1347368.HG964407_gene6726	1.348e-09	65.0	COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,1ZBJD@1386|Bacillus	91061|Bacilli	S	AI-2E family transporter	ydbI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WLSH1_k127_7339322_0	1196029.ALIM01000014_gene3668	1.033e-19	93.0	COG0628@1|root,COG0628@2|Bacteria,1TSBK@1239|Firmicutes,4HBYJ@91061|Bacilli,1ZBJD@1386|Bacillus	91061|Bacilli	S	AI-2E family transporter	ydbI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WLSH1_k127_7369350_3	398767.Glov_2914	2.823e-11	68.0	COG0028@1|root,COG1361@1|root,COG3386@1|root,COG3468@1|root,COG0028@2|Bacteria,COG1361@2|Bacteria,COG3386@2|Bacteria,COG3468@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
WLSH1_k127_7369350_2	1276229.SSYRP_v1c02150	4.528e-33	134.0	COG0087@1|root,COG0087@2|Bacteria,3WT04@544448|Tenericutes	544448|Tenericutes	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
WLSH1_k127_7369350_1	742733.HMPREF9469_05246	2.014e-37	148.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,21XPR@1506553|Lachnoclostridium	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
WLSH1_k127_7369350_4	525909.Afer_0400	8.574e-11	66.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4CN84@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
WLSH1_k127_7369350_0	771875.Ferpe_1413	2.998e-77	265.0	COG0090@1|root,COG0090@2|Bacteria,2GBXA@200918|Thermotogae	200918|Thermotogae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WLSH1_k127_7369350_5	1128421.JAGA01000002_gene700	6.964e-08	54.0	COG0090@1|root,COG0090@2|Bacteria,2NNR3@2323|unclassified Bacteria	2|Bacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WLSH1_k127_7444146_2	99598.Cal7507_4174	5.143e-12	71.0	COG1032@1|root,COG1032@2|Bacteria,1G3ZK@1117|Cyanobacteria,1HMX2@1161|Nostocales	1117|Cyanobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
WLSH1_k127_7444146_1	263820.PTO0315	3.191e-14	84.0	COG0438@1|root,arCOG01403@2157|Archaea	2157|Archaea	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH1_k127_7444146_0	683083.C414_000290001	6.934e-35	141.0	COG0451@1|root,COG0451@2|Bacteria,1QUEV@1224|Proteobacteria,43BNE@68525|delta/epsilon subdivisions,2YMGV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
WLSH1_k127_745678_0	696369.KI912183_gene1621	2.238e-104	349.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WLSH1_k127_745678_1	667014.Thein_1716	5.979e-29	117.0	COG1418@1|root,COG1418@2|Bacteria,2GIAK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
WLSH1_k127_7488816_0	593750.Metfor_1904	2.219e-05	50.0	COG1196@1|root,arCOG00371@2157|Archaea	2157|Archaea	D	Required for chromosome condensation and partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
WLSH1_k127_7546508_0	1379281.AVAG01000052_gene929	1.245e-44	176.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MG22@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WLSH1_k127_7547764_0	1158345.JNLL01000001_gene2037	2.004e-28	122.0	COG0758@1|root,COG0758@2|Bacteria,2G3ZI@200783|Aquificae	200783|Aquificae	LU	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
WLSH1_k127_7547764_1	748449.Halha_0643	6.433e-21	93.0	COG0322@1|root,COG0758@1|root,COG0322@2|Bacteria,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,3WAKH@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
WLSH1_k127_7568485_0	1042877.GQS_00060	2.437e-66	238.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTA2@28890|Euryarchaeota,243FX@183968|Thermococci	183968|Thermococci	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH1_k127_7568485_1	656519.Halsa_0839	1.504e-12	68.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,3WACN@53433|Halanaerobiales	186801|Clostridia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
WLSH1_k127_7572230_1	1274374.CBLK010000070_gene1125	1.591e-36	150.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WLSH1_k127_7572230_4	1410658.JHWI01000013_gene823	4.539e-20	94.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,3VPVT@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	-	-	-	-	-	-	-	-	-	-	DAHP_synth_1
WLSH1_k127_7572230_0	1050201.KB913034_gene546	6.173e-55	200.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,3VPVT@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	-	-	-	-	-	-	-	-	-	-	DAHP_synth_1
WLSH1_k127_7572230_2	1191523.MROS_2202	1.307e-32	130.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF2786,DUF45
WLSH1_k127_7572230_5	1226325.HMPREF1548_04464	2.317e-06	53.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,36GX1@31979|Clostridiaceae	186801|Clostridia	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WLSH1_k127_7572230_3	394503.Ccel_2522	2.948e-21	101.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,36F1A@31979|Clostridiaceae	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH1_k127_7579940_1	759914.BP951000_2294	5.166e-05	50.0	COG2373@1|root,COG2373@2|Bacteria,2J5M0@203691|Spirochaetes	203691|Spirochaetes	S	Alpha-2-macroglobulin family	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Big_5,MG1
WLSH1_k127_7579940_0	234267.Acid_2300	3.06e-16	93.0	COG2373@1|root,COG2373@2|Bacteria,3Y439@57723|Acidobacteria	57723|Acidobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
WLSH1_k127_770934_0	1382304.JNIL01000001_gene2809	2.915e-96	325.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,2786P@186823|Alicyclobacillaceae	91061|Bacilli	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH1_k127_7728850_0	1191523.MROS_0374	6.269e-124	401.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WLSH1_k127_7728850_1	945713.IALB_1404	1.822e-29	119.0	COG1004@1|root,COG1004@2|Bacteria	2|Bacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WLSH1_k127_7730952_0	1382304.JNIL01000001_gene2685	1.221e-13	78.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,4HAKE@91061|Bacilli,2787Z@186823|Alicyclobacillaceae	91061|Bacilli	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
WLSH1_k127_7741859_0	333138.LQ50_13520	3.501e-92	314.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli,1ZBY9@1386|Bacillus	91061|Bacilli	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WLSH1_k127_7753767_1	1347368.HG964407_gene6819	8.278e-22	96.0	COG1162@1|root,COG1162@2|Bacteria,1V272@1239|Firmicutes,4HPS4@91061|Bacilli	91061|Bacilli	S	RNHCP domain	-	-	-	-	-	-	-	-	-	-	-	-	RNHCP
WLSH1_k127_7753767_2	1121342.AUCO01000022_gene3009	7.843e-12	67.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,36EWX@31979|Clostridiaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
WLSH1_k127_7753767_0	1287488.HMPREF0671_11065	1.146e-25	109.0	COG0037@1|root,COG0037@2|Bacteria,4NEJS@976|Bacteroidetes,2FP2A@200643|Bacteroidia	976|Bacteroidetes	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
WLSH1_k127_7826617_5	656024.FsymDg_3437	0.0005679	45.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WLSH1_k127_7826617_1	1229783.C273_02950	2.78e-19	96.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,4GXC9@90964|Staphylococcaceae	91061|Bacilli	L	Belongs to the Nudix hydrolase family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
WLSH1_k127_7826617_3	759914.BP951000_0112	1.42e-12	75.0	COG1057@1|root,COG1057@2|Bacteria,2J65I@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
WLSH1_k127_7826617_2	272947.RP440	7.879e-13	72.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria,47F5E@766|Rickettsiales	766|Rickettsiales	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WLSH1_k127_7826617_4	335541.Swol_0584	3.149e-05	46.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,42JYG@68298|Syntrophomonadaceae	186801|Clostridia	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
WLSH1_k127_7826617_0	1262915.BN574_01333	1.639e-21	100.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,4H27N@909932|Negativicutes	909932|Negativicutes	H	NAD( ) synthase glutamine-hydrolyzing	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WLSH1_k127_7829852_0	498761.HM1_1406	9.742e-49	181.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WLSH1_k127_7829852_1	547144.HydHO_0290	3.226e-34	135.0	COG0100@1|root,COG0100@2|Bacteria,2G43F@200783|Aquificae	200783|Aquificae	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WLSH1_k127_786396_2	1403819.BATR01000049_gene1416	4.161e-35	143.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia,2ITXP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WLSH1_k127_786396_5	204773.HEAR3406	2.13e-07	53.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,472M2@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WLSH1_k127_786396_0	387092.NIS_1222	1.279e-161	515.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2YMSF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iIT341.HP1134	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WLSH1_k127_786396_1	1042876.PPS_5275	4.221e-38	147.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1YVWI@136845|Pseudomonas putida group	1236|Gammaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	iSbBS512_1146.SbBS512_E4187	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WLSH1_k127_786396_6	1449345.JHWC01000004_gene611	0.0001781	50.0	COG0711@1|root,COG0711@2|Bacteria,1Q2G9@1224|Proteobacteria,42VN4@68525|delta/epsilon subdivisions,2YQBE@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Belongs to the ATPase B chain family	atpF'	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
WLSH1_k127_786396_4	926550.CLDAP_05100	6.968e-08	57.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WLSH1_k127_786396_3	1382306.JNIM01000001_gene205	7.492e-17	88.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WLSH1_k127_7869061_0	556263.FSEG_00924	4.072e-95	327.0	COG0018@1|root,COG0018@2|Bacteria,378C4@32066|Fusobacteria	32066|Fusobacteria	J	Psort location Cytoplasmic, score 9.97	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WLSH1_k127_7869859_2	768706.Desor_4089	1.436e-08	58.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,2641K@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG2	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WLSH1_k127_7869859_0	1288963.ADIS_3499	2.256e-27	127.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47MTC@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WLSH1_k127_7869859_4	1117318.PRUB_05736	6.551e-05	49.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q1FC@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
WLSH1_k127_7869859_3	1515615.HQ41_05945	1.79e-08	59.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,2FM3B@200643|Bacteroidia,22VY6@171551|Porphyromonadaceae	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WLSH1_k127_7869859_1	223926.28807470	1.117e-20	99.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1XU61@135623|Vibrionales	135623|Vibrionales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18989	-	M00720	-	-	ko00000,ko00002,ko02000	2.A.6.2.30	-	-	ACR_tran
WLSH1_k127_7876006_0	1408164.MOLA814_01653	2.183e-56	202.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,1KPR0@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WLSH1_k127_7882499_0	1123230.ARQJ01000032_gene1300	6.086e-06	52.0	COG1073@1|root,COG1073@2|Bacteria,1V7CZ@1239|Firmicutes,4HJJ0@91061|Bacilli	91061|Bacilli	S	Serine hydrolase	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
WLSH1_k127_7883282_2	445973.CLOBAR_00311	0.0003338	46.0	COG4969@1|root,COG4969@2|Bacteria,1UI23@1239|Firmicutes,25N77@186801|Clostridia,25RX1@186804|Peptostreptococcaceae	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
WLSH1_k127_7883282_0	32057.KB217478_gene3484	9.817e-08	57.0	COG0268@1|root,COG0268@2|Bacteria,1G7PV@1117|Cyanobacteria,1HNY3@1161|Nostocales	1117|Cyanobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WLSH1_k127_7883282_1	1499967.BAYZ01000003_gene5877	2.439e-07	53.0	COG0290@1|root,COG0290@2|Bacteria,2NPDH@2323|unclassified Bacteria	2|Bacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WLSH1_k127_7918928_4	525903.Taci_0620	0.0006667	44.0	COG1420@1|root,COG1420@2|Bacteria,3TA2U@508458|Synergistetes	508458|Synergistetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
WLSH1_k127_7918928_3	457396.CSBG_02457	4.45e-26	117.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,36DW8@31979|Clostridiaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
WLSH1_k127_7918928_2	1122216.AUHW01000005_gene556	1.033e-29	123.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH1_k127_7918928_1	768706.Desor_5283	6.757e-33	136.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,260DV@186807|Peptococcaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH1_k127_7918928_0	742743.HMPREF9453_00693	1.859e-71	246.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4H22T@909932|Negativicutes	909932|Negativicutes	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH1_k127_7922183_0	1122128.AUEE01000002_gene1320	0.0003889	48.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,4GZ3W@90964|Staphylococcaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WLSH1_k127_7957443_2	926562.Oweho_2622	2.356e-07	53.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,1HWY3@117743|Flavobacteriia,2PARY@246874|Cryomorphaceae	976|Bacteroidetes	S	PFAM von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
WLSH1_k127_7957443_0	1410613.JNKF01000014_gene2067	4e-21	97.0	COG2304@1|root,COG2304@2|Bacteria,4NDUC@976|Bacteroidetes,2FNXM@200643|Bacteroidia	976|Bacteroidetes	S	Von Willebrand factor type A domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
WLSH1_k127_7957443_1	1123487.KB892849_gene286	9.521e-12	66.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,2VVUD@28216|Betaproteobacteria,2KXCR@206389|Rhodocyclales	206389|Rhodocyclales	K	TfoX N-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
WLSH1_k127_795932_0	323259.Mhun_1971	2.542e-58	211.0	COG1948@1|root,arCOG02284@2157|Archaea,2XT7B@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Beta propeller domain	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Beta_propel,Inhibitor_I42
WLSH1_k127_795932_2	28229.ND2E_4302	2.156e-16	85.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1R5QM@1224|Proteobacteria,1S0WF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
WLSH1_k127_795932_4	177437.HRM2_32220	2.15e-15	79.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,42QMQ@68525|delta/epsilon subdivisions,2WN4S@28221|Deltaproteobacteria,2MJWK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GGDEF
WLSH1_k127_795932_5	1280685.AUKC01000077_gene3302	1.301e-06	51.0	2DRFJ@1|root,33BHY@2|Bacteria,1UPE7@1239|Firmicutes,25HEA@186801|Clostridia,4C0D6@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_795932_6	465817.ETA_29970	2.525e-06	49.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,3X5EE@551|Erwinia	1236|Gammaproteobacteria	M	silverDB	-	-	-	-	-	-	-	-	-	-	-	-	PAAR_motif,RHS,RHS_repeat,Tox-HNH-EHHH
WLSH1_k127_795932_3	1499968.TCA2_3163	1.956e-15	77.0	2DXNX@1|root,345RV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_795932_1	679926.Mpet_1589	1.33e-18	91.0	COG3209@1|root,arCOG12091@2157|Archaea,2Y87Z@28890|Euryarchaeota,2NBP1@224756|Methanomicrobia	224756|Methanomicrobia	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_7980450_0	1121342.AUCO01000005_gene333	1.712e-05	55.0	COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,24DUI@186801|Clostridia	186801|Clostridia	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
WLSH1_k127_7981117_0	1192124.LIG30_0509	2.497e-56	211.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K2HZ@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
WLSH1_k127_7983964_1	883169.HMPREF9719_01566	1.358e-106	353.0	COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,22JHM@1653|Corynebacteriaceae	201174|Actinobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH1_k127_7983964_11	1184267.A11Q_1589	0.0001727	45.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2MU8J@213481|Bdellovibrionales,2WIVS@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
WLSH1_k127_7983964_7	1121335.Clst_2461	1.793e-08	58.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WLSH1_k127_7983964_10	292459.STH2540	7.308e-06	50.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WLSH1_k127_7983964_0	289376.THEYE_A1448	1.208e-195	616.0	COG0050@1|root,COG0050@2|Bacteria,3J0DG@40117|Nitrospirae	40117|Nitrospirae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
WLSH1_k127_7983964_3	926569.ANT_10030	4.629e-28	117.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi	200795|Chloroflexi	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
WLSH1_k127_7983964_4	755732.Fluta_2697	4.771e-17	82.0	COG0227@1|root,COG0227@2|Bacteria,4NS7Q@976|Bacteroidetes,1I3YG@117743|Flavobacteriia,2PB6U@246874|Cryomorphaceae	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WLSH1_k127_7983964_6	688269.Theth_0790	4.248e-11	67.0	COG0228@1|root,COG0228@2|Bacteria,2GD7M@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WLSH1_k127_7983964_5	264201.pc0357	2.717e-11	66.0	COG1837@1|root,COG1837@2|Bacteria,2JGBY@204428|Chlamydiae	204428|Chlamydiae	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
WLSH1_k127_7983964_2	697281.Mahau_2357	9.869e-99	336.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WLSH1_k127_8002541_0	1437425.CSEC_0579	2.046e-103	351.0	COG0215@1|root,COG0215@2|Bacteria,2JFNB@204428|Chlamydiae	204428|Chlamydiae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
WLSH1_k127_8002541_1	580332.Slit_2952	1.835e-06	49.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,44W0G@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WLSH1_k127_8050037_1	485917.Phep_1358	2.518e-07	54.0	COG3391@1|root,COG4632@1|root,COG3391@2|Bacteria,COG4632@2|Bacteria,4NNEF@976|Bacteroidetes,1ISMB@117747|Sphingobacteriia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA,NHL,TIG
WLSH1_k127_8050037_0	1123278.KB893615_gene5179	1.396e-07	56.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
WLSH1_k127_8050037_2	511051.CSE_15450	0.000102	53.0	COG1470@1|root,COG3391@1|root,COG1470@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_6,Cu_amine_oxidN1,DUF4384,DUF5128,F5_F8_type_C,NHL
WLSH1_k127_8050037_3	484770.UFO1_2245	0.0002458	47.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	gspG	-	-	ko:K02456,ko:K02650,ko:K02655	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl,T2SSG
WLSH1_k127_8060934_3	1267580.AF6_0048	2.528e-11	64.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,21VIY@150247|Anoxybacillus	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WLSH1_k127_8060934_0	1174504.AJTN02000203_gene2773	2.96e-35	137.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,1ZC7I@1386|Bacillus	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WLSH1_k127_8060934_1	388919.SSA_1297	1.457e-23	102.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli,1WQJR@1305|Streptococcus sanguinis	91061|Bacilli	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WLSH1_k127_8060934_2	536232.CLM_3842	1.184e-15	81.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,36DMH@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WLSH1_k127_8060934_4	1223521.BBJX01000004_gene2224	0.0005322	49.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,4ABCV@80864|Comamonadaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
WLSH1_k127_8108874_0	1200557.JHWV01000001_gene476	0.0009684	46.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4H5KC@909932|Negativicutes	909932|Negativicutes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH1_k127_8177559_0	990285.RGCCGE502_22705	0.0001844	55.0	COG5283@1|root,COG5283@2|Bacteria,1NFKU@1224|Proteobacteria,2U1H4@28211|Alphaproteobacteria,4BCD7@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3,PhageMin_Tail
WLSH1_k127_8288276_0	2325.TKV_c16700	1.224e-77	278.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,42FUU@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WLSH1_k127_835043_2	1121105.ATXL01000058_gene2026	0.000314	48.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli,4B0Q5@81852|Enterococcaceae	91061|Bacilli	L	DNA polymerase III, delta	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WLSH1_k127_835043_0	1123020.AUIE01000007_gene3216	5.269e-09	61.0	COG3209@1|root,COG3209@2|Bacteria,1NF2V@1224|Proteobacteria	1224|Proteobacteria	M	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WLSH1_k127_835043_1	1227349.C170_12405	0.0001525	47.0	COG4099@1|root,COG5263@1|root,COG4099@2|Bacteria,COG5263@2|Bacteria,1VS9V@1239|Firmicutes,4HUV4@91061|Bacilli,26TZF@186822|Paenibacillaceae	91061|Bacilli	DZ	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Peptidase_S9,SLH,fn3
WLSH1_k127_844530_1	880073.Calab_2467	5.853e-28	113.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
WLSH1_k127_844530_0	880073.Calab_2466	7.952e-97	319.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH1_k127_8569910_0	1410608.JNKX01000019_gene2758	1.573e-45	169.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,2FMH0@200643|Bacteroidia,4AMVJ@815|Bacteroidaceae	976|Bacteroidetes	L	single-stranded-DNA-specific exonuclease recJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH1_k127_8569910_4	235909.GK0594	1.427e-05	48.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4HU64@91061|Bacilli,1WHE6@129337|Geobacillus	91061|Bacilli	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH1_k127_8569910_1	373903.Hore_12210	5.173e-42	164.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WB7F@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
WLSH1_k127_8569910_2	1239962.C943_04447	1.372e-16	93.0	COG5267@1|root,COG5267@2|Bacteria,4NHSB@976|Bacteroidetes,47MD4@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
WLSH1_k127_8569910_5	1122176.KB903549_gene1245	4.13e-05	53.0	COG4102@1|root,COG4102@2|Bacteria,4NFFC@976|Bacteroidetes,1IWTR@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
WLSH1_k127_8569910_3	639030.JHVA01000001_gene213	1.034e-08	68.0	COG4102@1|root,COG4102@2|Bacteria,3Y2YD@57723|Acidobacteria,2JI17@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
WLSH1_k127_8580374_0	1254432.SCE1572_07400	4.788e-29	118.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2YXKD@29|Myxococcales	28221|Deltaproteobacteria	C	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205,1.7.1.7	ko:K00088,ko:K00364	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R01134,R08240	RC00143,RC00457,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WLSH1_k127_8580374_1	1002339.HMPREF9373_1380	1.935e-11	68.0	2CFWE@1|root,3430F@2|Bacteria,1NY3W@1224|Proteobacteria,1SQNA@1236|Gammaproteobacteria,3NM6K@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_8597853_5	290512.Paes_0433	2.015e-06	55.0	COG1185@1|root,COG1432@1|root,COG1185@2|Bacteria,COG1432@2|Bacteria,1FEI0@1090|Chlorobi	1090|Chlorobi	J	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
WLSH1_k127_8597853_0	202954.BBNK01000003_gene2656	1.562e-37	153.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,3NJI2@468|Moraxellaceae	1236|Gammaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WLSH1_k127_8597853_1	865861.AZSU01000003_gene1926	9.997e-35	138.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,36HY1@31979|Clostridiaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WLSH1_k127_8597853_4	331869.BAL199_15293	1.232e-06	54.0	2A9WW@1|root,30Z4Z@2|Bacteria,1PM1G@1224|Proteobacteria,2UWN1@28211|Alphaproteobacteria,4BT5B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_8597853_3	379066.GAU_1176	5.502e-11	68.0	COG2385@1|root,COG2385@2|Bacteria,1ZT25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
WLSH1_k127_8597853_2	479434.Sthe_0357	4.755e-26	122.0	COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia	189775|Thermomicrobia	PT	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
WLSH1_k127_8635064_3	1562701.BBOF01000009_gene53	1.61e-06	56.0	2F8II@1|root,340XB@2|Bacteria,1N0UB@1224|Proteobacteria,2WIF4@28216|Betaproteobacteria,1K8ZD@119060|Burkholderiaceae	1224|Proteobacteria	S	Carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_8635064_0	352165.HMPREF7215_0927	2.384e-55	199.0	COG0343@1|root,COG0343@2|Bacteria,3TA1P@508458|Synergistetes	508458|Synergistetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WLSH1_k127_8635064_1	679937.Bcop_1431	2.108e-27	113.0	COG0343@1|root,COG0343@2|Bacteria,4NE15@976|Bacteroidetes,2FMUM@200643|Bacteroidia,4AN36@815|Bacteroidaceae	976|Bacteroidetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WLSH1_k127_8635064_2	861452.HMPREF9093_01059	2.128e-23	100.0	COG0343@1|root,COG0343@2|Bacteria,378C1@32066|Fusobacteria	32066|Fusobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WLSH1_k127_8651140_4	751944.HALDL1_02790	0.0006339	46.0	COG2220@1|root,arCOG00497@2157|Archaea,2XVZW@28890|Euryarchaeota,23UG7@183963|Halobacteria	183963|Halobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	ko:K14952	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	Lactamase_B_3
WLSH1_k127_8651140_1	904293.HMPREF9176_1169	1.464e-25	113.0	COG2249@1|root,COG2249@2|Bacteria,1V59U@1239|Firmicutes,4HHZC@91061|Bacilli	91061|Bacilli	S	NADPH-quinone reductase (modulator of drug activity B)	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
WLSH1_k127_8651140_3	1169152.AXVD01000028_gene3182	1.038e-10	65.0	COG4997@1|root,COG4997@2|Bacteria,2INKW@201174|Actinobacteria,4G4K9@85025|Nocardiaceae	201174|Actinobacteria	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
WLSH1_k127_8651140_0	469618.FVAG_00297	3.173e-40	162.0	COG0341@1|root,COG0341@2|Bacteria,378NT@32066|Fusobacteria	32066|Fusobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH1_k127_8651140_5	1150864.MILUP08_42650	0.0006817	46.0	28HZQ@1|root,2Z84P@2|Bacteria,2H0F4@201174|Actinobacteria,4DEA2@85008|Micromonosporales	201174|Actinobacteria	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
WLSH1_k127_8651140_2	485913.Krac_5206	4.402e-14	78.0	COG3451@1|root,COG3451@2|Bacteria	2|Bacteria	U	multi-organism process	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87,PrgI
WLSH1_k127_8682790_1	56780.SYN_02789	4.837e-18	86.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2MQBE@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WLSH1_k127_8682790_0	1232410.KI421413_gene701	1.627e-67	237.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42QX1@68525|delta/epsilon subdivisions,2WMNH@28221|Deltaproteobacteria,43TQD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
WLSH1_k127_8704122_3	694429.Pyrfu_0043	4.28e-05	51.0	COG0237@1|root,arCOG01045@2157|Archaea,2XQTJ@28889|Crenarchaeota	28889|Crenarchaeota	F	Belongs to the UPF0200 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_17,AAA_18
WLSH1_k127_8704122_1	386415.NT01CX_1296	2.1e-69	247.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,36DHP@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH1_k127_8704122_0	1121930.AQXG01000001_gene1270	2.291e-120	397.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,1IR52@117747|Sphingobacteriia	976|Bacteroidetes	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
WLSH1_k127_8704122_2	1211813.CAPH01000016_gene759	1.3e-38	149.0	COG0587@1|root,COG0587@2|Bacteria,4NFA0@976|Bacteroidetes,2FNND@200643|Bacteroidia,22UBQ@171550|Rikenellaceae	976|Bacteroidetes	L	DNA polymerase alpha chain like domain	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
WLSH1_k127_8756630_0	349161.Dred_0684	3.252e-118	388.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,260UE@186807|Peptococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WLSH1_k127_8756630_1	574087.Acear_0752	1.155e-55	207.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,24948@186801|Clostridia,3WA9N@53433|Halanaerobiales	186801|Clostridia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WLSH1_k127_8773470_0	1294142.CINTURNW_3339	7.086e-56	197.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,36I3G@31979|Clostridiaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
WLSH1_k127_8773470_2	1196322.A370_00680	2.208e-19	87.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,36I3G@31979|Clostridiaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
WLSH1_k127_8773470_1	203119.Cthe_1345	1.1e-39	150.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,3WJCT@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WLSH1_k127_8777986_0	1047013.AQSP01000118_gene1252	1.497e-15	77.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_8807149_0	1121035.AUCH01000002_gene1678	2.366e-42	159.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VNJW@28216|Betaproteobacteria,2KW08@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
WLSH1_k127_8807149_3	82654.Pse7367_1168	1.013e-06	52.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G107@1117|Cyanobacteria,1H9NE@1150|Oscillatoriales	1117|Cyanobacteria	T	CHASE2 domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WLSH1_k127_8807149_1	1410609.JHVB01000001_gene1992	2.697e-17	84.0	COG2114@1|root,COG2114@2|Bacteria,2J6Q9@203691|Spirochaetes	203691|Spirochaetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
WLSH1_k127_8807149_4	1121004.ATVC01000014_gene2031	1.096e-05	50.0	COG2114@1|root,COG2114@2|Bacteria,1MWHK@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	cyaG2	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,NTP_transf_9
WLSH1_k127_8807149_2	1123517.JOMR01000001_gene1613	6.341e-16	83.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,GAF,GAF_2,Guanylate_cyc,HAMP,PAS_9,dCache_1
WLSH1_k127_8851528_0	497965.Cyan7822_4390	1.016e-05	52.0	COG1950@1|root,COG1950@2|Bacteria,1G7RB@1117|Cyanobacteria,3KIDQ@43988|Cyanothece	1117|Cyanobacteria	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
WLSH1_k127_8851528_2	632518.Calow_0503	0.0001227	51.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,42F33@68295|Thermoanaerobacterales	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WLSH1_k127_8858276_2	264462.Bd2784	4.754e-05	45.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2MTH2@213481|Bdellovibrionales,2WIIV@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	aconitate hydratase	aco	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WLSH1_k127_8858276_1	742740.HMPREF9474_00953	1.696e-06	50.0	COG2199@1|root,COG2199@2|Bacteria,COG3706@2|Bacteria,1TSTI@1239|Firmicutes,24AJT@186801|Clostridia,21ZM4@1506553|Lachnoclostridium	186801|Clostridia	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,dCache_1
WLSH1_k127_8858276_0	1071400.LBUCD034_1505	1.089e-73	253.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli,3F3P2@33958|Lactobacillaceae	91061|Bacilli	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WLSH1_k127_8858276_3	246197.MXAN_1933	0.0002875	51.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2YUDA@29|Myxococcales	28221|Deltaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WLSH1_k127_8870381_0	1121333.JMLH01000057_gene1707	1.932e-48	185.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,3VPWG@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Responsible for synthesis of pseudouridine from uracil	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2,S4
WLSH1_k127_9005620_2	449447.MAE_60350	4.465e-05	50.0	COG3464@1|root,COG3464@2|Bacteria,1G0IQ@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH1_k127_9005620_1	592015.HMPREF1705_00894	7.41e-12	74.0	COG3464@1|root,COG3464@2|Bacteria,3TCGB@508458|Synergistetes	2|Bacteria	L	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH1_k127_9005620_0	930945.SiRe_1160	3.35e-12	67.0	COG0396@1|root,arCOG04236@2157|Archaea,2XQ7X@28889|Crenarchaeota	28889|Crenarchaeota	O	TIGRFAM FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WLSH1_k127_9044129_0	1047013.AQSP01000118_gene1252	1.235e-66	239.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9048962_2	706439.HMPREF9057_02911	2.61e-07	53.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4D3R4@85005|Actinomycetales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
WLSH1_k127_9048962_3	1463845.JOIG01000006_gene1038	9.868e-07	53.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria	201174|Actinobacteria	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WLSH1_k127_9048962_0	383372.Rcas_1996	6.564e-16	87.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,375FQ@32061|Chloroflexia	32061|Chloroflexia	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WLSH1_k127_9048962_4	747365.Thena_0719	0.000404	47.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,42EPS@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM glycosyl transferase, family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366,ko:K21464	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WLSH1_k127_9048962_1	204536.SULAZ_0853	1.245e-11	66.0	COG5009@1|root,COG5009@2|Bacteria,2G3MT@200783|Aquificae	200783|Aquificae	M	Penicillin-binding protein 1A	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WLSH1_k127_9051893_0	227086.JGI_V11_85812	1.159e-109	374.0	COG1243@1|root,KOG2535@2759|Eukaryota	2759|Eukaryota	BK	phosphorylase kinase regulator activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
WLSH1_k127_9051893_1	1250278.JQNQ01000001_gene164	4.525e-10	63.0	COG0189@1|root,COG0189@2|Bacteria,4NFXS@976|Bacteroidetes,1I0AD@117743|Flavobacteriia	976|Bacteroidetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_907418_1	1519464.HY22_06390	2.595e-21	95.0	COG0859@1|root,COG0859@2|Bacteria,1FF11@1090|Chlorobi	1090|Chlorobi	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WLSH1_k127_907418_0	1191523.MROS_1306	1.545e-70	243.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WLSH1_k127_9171268_1	1121396.KB893074_gene3000	8.469e-44	163.0	COG0423@1|root,COG0423@2|Bacteria,1R3VX@1224|Proteobacteria,42MHG@68525|delta/epsilon subdivisions,2WKJC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
WLSH1_k127_9171268_0	929506.CbC4_0171	7.72e-115	377.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,36DC4@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
WLSH1_k127_9264264_0	1123073.KB899244_gene186	1.608e-07	57.0	COG1470@1|root,COG3209@1|root,COG5184@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria,1N55D@1224|Proteobacteria,1T481@1236|Gammaproteobacteria,1XD8U@135614|Xanthomonadales	135614|Xanthomonadales	DMZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG
WLSH1_k127_9264264_2	414684.RC1_1137	1.866e-06	52.0	COG5301@1|root,COG5301@2|Bacteria,1N59Q@1224|Proteobacteria,2UN28@28211|Alphaproteobacteria,2JWW2@204441|Rhodospirillales	204441|Rhodospirillales	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9264264_1	1304888.ATWF01000002_gene248	1.176e-06	56.0	COG4733@1|root,COG5301@1|root,COG4733@2|Bacteria,COG5301@2|Bacteria	2|Bacteria	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,NPCBM,Phage-tail_3,Phage_fiber_2,fn3
WLSH1_k127_9264264_3	309799.DICTH_0726	2.366e-05	50.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Lectin_C,N_methyl,SBP_bac_10,T2SSG
WLSH1_k127_9300458_0	1382306.JNIM01000001_gene3556	3.4e-134	440.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WLSH1_k127_9315672_0	37659.JNLN01000001_gene2590	6.926e-12	68.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,36F0J@31979|Clostridiaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WLSH1_k127_9315672_1	396588.Tgr7_0172	1.003e-05	51.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WLSH1_k127_9347346_1	452637.Oter_1561	1.095e-45	173.0	COG0469@1|root,COG0469@2|Bacteria,46SBJ@74201|Verrucomicrobia,3K7C0@414999|Opitutae	414999|Opitutae	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WLSH1_k127_9347346_0	443254.Marpi_0537	1.512e-85	301.0	COG1164@1|root,COG1164@2|Bacteria,2GCJ4@200918|Thermotogae	200918|Thermotogae	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH1_k127_9365770_0	439235.Dalk_1419	1.869e-67	237.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2MJIB@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH1_k127_9399444_2	1045858.Bint_1485	2.863e-24	105.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2J65C@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WLSH1_k127_9399444_0	927704.SELR_17760	2.31e-63	226.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,4H27N@909932|Negativicutes	909932|Negativicutes	H	NAD( ) synthase glutamine-hydrolyzing	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WLSH1_k127_9399444_4	931276.Cspa_c34350	4.77e-17	81.0	COG0635@1|root,COG1051@1|root,COG0635@2|Bacteria,COG1051@2|Bacteria,1UZNM@1239|Firmicutes,249M8@186801|Clostridia,36R7U@31979|Clostridiaceae	186801|Clostridia	FH	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Radical_SAM
WLSH1_k127_9399444_3	1280686.AUKE01000014_gene609	1.518e-17	83.0	COG0635@1|root,COG1051@1|root,COG0635@2|Bacteria,COG1051@2|Bacteria,1TST7@1239|Firmicutes,249C3@186801|Clostridia,4BXVE@830|Butyrivibrio	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Radical_SAM
WLSH1_k127_9422044_1	638302.HMPREF0908_1323	4.389e-05	46.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,4H3EA@909932|Negativicutes	909932|Negativicutes	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
WLSH1_k127_9422044_0	1027273.GZ77_23665	2.244e-13	76.0	COG1378@1|root,COG1378@2|Bacteria,1PZ3N@1224|Proteobacteria,1RS6X@1236|Gammaproteobacteria,1XITG@135619|Oceanospirillales	135619|Oceanospirillales	K	Transcriptional regulator, TrmB	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
WLSH1_k127_9520733_2	1408473.JHXO01000022_gene2532	1.13e-19	91.0	2E4EA@1|root,32Z9I@2|Bacteria,4NTWC@976|Bacteroidetes,2FU6R@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9520733_7	1407650.BAUB01000037_gene2911	0.0001088	45.0	2DMNG@1|root,32SP1@2|Bacteria,1G7Q6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9520733_4	1121267.JHZL01000002_gene1115	5.419e-09	57.0	2AK5G@1|root,31AVC@2|Bacteria,1Q693@1224|Proteobacteria,432NC@68525|delta/epsilon subdivisions,2YSJH@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9520733_3	411470.RUMGNA_02974	3.766e-13	71.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9520733_6	509191.AEDB02000042_gene4877	4.62e-06	48.0	2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,24W9H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9520733_1	1382230.ASAP_2763	1.691e-28	120.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,2UWJH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9520733_0	1121428.DESHY_80091___1	1.288e-153	505.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WLSH1_k127_9525386_0	926556.Echvi_1551	8.508e-28	125.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,47K19@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WLSH1_k127_9563672_0	991.IW20_12375	1.506e-135	439.0	COG4108@1|root,COG4108@2|Bacteria,4NFEZ@976|Bacteroidetes,1HY71@117743|Flavobacteriia,2NSDD@237|Flavobacterium	976|Bacteroidetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
WLSH1_k127_9566041_1	929556.Solca_3424	8.419e-05	48.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WLSH1_k127_9566041_0	1313421.JHBV01000024_gene5042	1.342e-19	100.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,4NIIR@976|Bacteroidetes,1IPF7@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WLSH1_k127_9584332_3	332101.JIBU02000005_gene319	1.929e-06	56.0	2BGQZ@1|root,32AQ0@2|Bacteria,1UGJA@1239|Firmicutes,25P1N@186801|Clostridia,36TFV@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9584332_1	411901.BACCAC_01620	2.746e-20	96.0	COG0641@1|root,COG0641@2|Bacteria,4NJSB@976|Bacteroidetes,2FR91@200643|Bacteroidia	976|Bacteroidetes	C	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
WLSH1_k127_9584332_0	391625.PPSIR1_25641	4.511e-43	162.0	COG0641@1|root,COG0641@2|Bacteria,1NG2E@1224|Proteobacteria,43BH9@68525|delta/epsilon subdivisions,2X6VN@28221|Deltaproteobacteria,2YYEN@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
WLSH1_k127_9584332_2	515622.bpr_I1900	1.433e-08	58.0	COG0641@1|root,COG0641@2|Bacteria,1UZY1@1239|Firmicutes,24B2I@186801|Clostridia,4C0XV@830|Butyrivibrio	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
WLSH1_k127_9638411_1	1192034.CAP_3726	1.049e-05	50.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2YXKD@29|Myxococcales	28221|Deltaproteobacteria	C	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205,1.7.1.7	ko:K00088,ko:K00364	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R01134,R08240	RC00143,RC00457,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WLSH1_k127_9638411_0	1499967.BAYZ01000076_gene830	6.448e-34	138.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WLSH1_k127_9639229_2	1123296.JQKE01000020_gene1029	0.0009656	49.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria	1224|Proteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SLT
WLSH1_k127_9639229_0	1304284.L21TH_0428	5.09e-06	53.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,36KNM@31979|Clostridiaceae	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
WLSH1_k127_9639229_1	56107.Cylst_0952	1.048e-05	55.0	COG2348@1|root,COG2348@2|Bacteria,1G1W5@1117|Cyanobacteria	1117|Cyanobacteria	V	FemAB family	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WLSH1_k127_9648563_0	1094980.Mpsy_0517	1.082e-33	143.0	COG2202@1|root,arCOG02350@1|root,arCOG02376@1|root,arCOG02350@2157|Archaea,arCOG02376@2157|Archaea,arCOG06918@2157|Archaea,2Y82C@28890|Euryarchaeota,2NBNJ@224756|Methanomicrobia	2157|Archaea	T	His Kinase A (phospho-acceptor) domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	GAF,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
WLSH1_k127_9674172_0	936596.HMPREF1495_0149	1.086e-41	158.0	COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,249AN@186801|Clostridia	186801|Clostridia	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
WLSH1_k127_9674172_1	243365.CV_1028	1.979e-26	111.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,2KR5B@206351|Neisseriales	206351|Neisseriales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
WLSH1_k127_9674172_2	1188240.MYEA_6840	7.138e-05	47.0	COG0262@1|root,COG0262@2|Bacteria,3WTUP@544448|Tenericutes	544448|Tenericutes	H	Dihydrofolate reductase	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
WLSH1_k127_9780233_0	1313301.AUGC01000003_gene2006	1.267e-200	642.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes	976|Bacteroidetes	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WLSH1_k127_9780233_1	457396.CSBG_00338	3.26e-44	165.0	COG3103@1|root,COG4991@2|Bacteria,1V4Q0@1239|Firmicutes,24G0J@186801|Clostridia,36I4A@31979|Clostridiaceae	186801|Clostridia	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF285
WLSH1_k127_9781344_1	1295642.H839_05814	7.454e-22	107.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,1WH6H@129337|Geobacillus	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-TG,RHS_repeat
WLSH1_k127_9781344_0	1318628.MARLIPOL_09971	4.447e-48	189.0	COG1372@1|root,COG1520@1|root,COG3209@1|root,COG1372@2|Bacteria,COG1520@2|Bacteria,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,46DDZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	LM	Rhs Family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF5122,He_PIG,PT-HINT,RHS_repeat
WLSH1_k127_9781344_4	862751.SACTE_5519	7.097e-06	54.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria	201174|Actinobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
WLSH1_k127_9781344_2	679926.Mpet_1589	5.502e-14	82.0	COG3209@1|root,arCOG12091@2157|Archaea,2Y87Z@28890|Euryarchaeota,2NBP1@224756|Methanomicrobia	224756|Methanomicrobia	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH1_k127_9781344_3	679935.Alfi_0073	8.271e-07	54.0	COG3621@1|root,COG3621@2|Bacteria,4NYS9@976|Bacteroidetes,2FS0H@200643|Bacteroidia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Laminin_G_3
WLSH1_k127_9783060_0	634956.Geoth_3268	1.088e-32	138.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HUAQ@91061|Bacilli,1WHAR@129337|Geobacillus	91061|Bacilli	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH1_k127_9831311_0	1033740.CAEW01000030_gene59	2.288e-75	259.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli,26DM2@186818|Planococcaceae	91061|Bacilli	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WLSH1_k127_9833266_0	387631.Asulf_00034	3.977e-32	134.0	COG0125@1|root,arCOG01891@2157|Archaea,2Y11Y@28890|Euryarchaeota	28890|Euryarchaeota	F	Thymidylate kinase	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WLSH1_k127_9833266_1	525904.Tter_2798	1.109e-21	98.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	epsD	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754,ko:K19422	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH1_k127_9875830_1	1540257.JQMW01000009_gene3151	2.566e-25	109.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,36DG2@31979|Clostridiaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH1_k127_9875830_0	1384057.CD33_18735	1.455e-57	204.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3IWUH@400634|Lysinibacillus	91061|Bacilli	NU	Type II secretion system protein E	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH1_k127_9879740_0	1265505.ATUG01000002_gene2465	6.624e-13	74.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions,2WKXG@28221|Deltaproteobacteria,2MN38@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
WLSH1_k127_989265_0	985665.HPL003_23505	4.12e-71	254.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,26RZ6@186822|Paenibacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WLSH1_k127_9924860_1	745411.B3C1_00940	4.347e-20	92.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1J6G9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WLSH1_k127_9924860_2	1121020.JIAG01000001_gene1214	2.574e-10	64.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,1W7T9@1268|Micrococcaceae	201174|Actinobacteria	K	Crp Fnr family	glxR	GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH1_k127_9924860_0	1227352.C173_17291	1.449e-111	371.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli,271UU@186822|Paenibacillaceae	91061|Bacilli	J	tRNA synthetases class II (A)	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_2c,tRNA_SAD
WLSH1_k127_9933357_0	1408322.JHYK01000017_gene1705	3.214e-66	235.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,27IHU@186928|unclassified Lachnospiraceae	186801|Clostridia	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WLSH1_k127_9933357_1	936375.HMPREF1152_0361	0.0001665	45.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WLSH1_k127_9963293_0	1124780.ANNU01000010_gene3624	2.961e-202	644.0	COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,47JCZ@768503|Cytophagia	976|Bacteroidetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WLSH1_k127_9985876_0	479433.Caci_0451	1.441e-06	60.0	COG1470@1|root,COG1470@2|Bacteria,2I2TR@201174|Actinobacteria	201174|Actinobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF916
## 988 queries scanned
## Total time (seconds): 4.246464252471924
## Rate: 232.66 q/s