## Tue Dec 16 19:05:32 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WLSH2_bin.20.fa -m mmseqs --itype genome -o WLSH2_bin.20 --output_dir /data/result/bins/wyx/egg/WLSH2_bin.20 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WLSH2_k127_10220876_3	244582.JQAK01000001_gene859	1.817e-124	408.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,47F9J@766|Rickettsiales	766|Rickettsiales	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH2_k127_10220876_2	91604.ID47_08735	2.378e-139	449.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,47ETT@766|Rickettsiales	766|Rickettsiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WLSH2_k127_10220876_0	985867.AEWF01000002_gene1576	1.275e-237	743.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2TSX1@28211|Alphaproteobacteria,47EV1@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
WLSH2_k127_10220876_5	91604.ID47_05625	2.044e-56	206.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,47FCQ@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
WLSH2_k127_10220876_1	244582.JQAK01000001_gene702	2.429e-188	593.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2TQT3@28211|Alphaproteobacteria,47EZ3@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
WLSH2_k127_10220876_4	244581.IM40_08080	5.237e-113	373.0	COG1672@1|root,COG1672@2|Bacteria,1MWJX@1224|Proteobacteria,2V4HQ@28211|Alphaproteobacteria,47FYU@766|Rickettsiales	766|Rickettsiales	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
WLSH2_k127_1041284_7	128390.XP_009470024.1	7.909e-05	55.0	28M43@1|root,2QTM0@2759|Eukaryota,39R11@33154|Opisthokonta,3BBTA@33208|Metazoa,3CZDB@33213|Bilateria,480I5@7711|Chordata,495WX@7742|Vertebrata,4GI4A@8782|Aves	33208|Metazoa	S	Golgin subfamily A member 4	GOLGA4	GO:0000138,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005802,GO:0005829,GO:0006810,GO:0006892,GO:0006893,GO:0007275,GO:0007399,GO:0008104,GO:0008150,GO:0008361,GO:0009987,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016192,GO:0017016,GO:0017137,GO:0019899,GO:0022008,GO:0022603,GO:0022604,GO:0030154,GO:0030306,GO:0030307,GO:0030516,GO:0031267,GO:0031344,GO:0031346,GO:0031984,GO:0031985,GO:0032501,GO:0032502,GO:0032535,GO:0033036,GO:0034613,GO:0040008,GO:0042802,GO:0042803,GO:0042886,GO:0043001,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045927,GO:0046983,GO:0048193,GO:0048518,GO:0048522,GO:0048638,GO:0048639,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050789,GO:0050793,GO:0050794,GO:0051020,GO:0051094,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051960,GO:0051962,GO:0060284,GO:0061387,GO:0061951,GO:0065007,GO:0065008,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0072659,GO:0090066,GO:0090150,GO:0098791,GO:0098876,GO:0120035,GO:1990778,GO:2000026	-	ko:K20283	-	-	-	-	ko00000,ko04131	-	-	-	GRIP
WLSH2_k127_1041284_1	985867.AEWF01000004_gene180	3.631e-221	703.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,47F4X@766|Rickettsiales	766|Rickettsiales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
WLSH2_k127_1041284_0	244582.JQAK01000001_gene1067	1.413e-239	752.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,47F2W@766|Rickettsiales	766|Rickettsiales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
WLSH2_k127_1041284_6	244582.JQAK01000001_gene1066	5.252e-52	186.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2UBXS@28211|Alphaproteobacteria,47FFY@766|Rickettsiales	766|Rickettsiales	C	COG3288 NAD NADP transhydrogenase alpha subunit	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
WLSH2_k127_1041284_3	91604.ID47_03225	1.386e-161	516.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,47F1Z@766|Rickettsiales	766|Rickettsiales	C	COG3288 NAD NADP transhydrogenase alpha subunit	pntAA	GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WLSH2_k127_1041284_4	1121022.ABENE_19125	3.234e-147	479.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria,2KI7S@204458|Caulobacterales	204458|Caulobacterales	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_1041284_5	244582.JQAK01000001_gene802	1.517e-56	201.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,47FMU@766|Rickettsiales	766|Rickettsiales	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WLSH2_k127_1041284_2	91604.ID47_03815	1.086e-184	587.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TQJR@28211|Alphaproteobacteria,47FVV@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WLSH2_k127_10633501_4	985867.AEWF01000001_gene2066	2.622e-124	411.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,47EXW@766|Rickettsiales	766|Rickettsiales	G	Phosphoglucose isomerase	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WLSH2_k127_10633501_13	985867.AEWF01000006_gene561	2.681e-87	297.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,47F9G@766|Rickettsiales	766|Rickettsiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
WLSH2_k127_10633501_12	985867.AEWF01000006_gene560	1.812e-96	319.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,47F58@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
WLSH2_k127_10633501_20	985867.AEWF01000001_gene1957	6.259e-41	158.0	COG1495@1|root,COG1495@2|Bacteria	2|Bacteria	O	protein disulfide oxidoreductase activity	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
WLSH2_k127_10633501_16	985867.AEWF01000001_gene1956	8.713e-67	235.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2U78A@28211|Alphaproteobacteria,47FM9@766|Rickettsiales	766|Rickettsiales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH2_k127_10633501_9	91604.ID47_04250	2.649e-111	361.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,47F8N@766|Rickettsiales	766|Rickettsiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WLSH2_k127_10633501_21	760192.Halhy_0668	2.821e-33	144.0	COG0845@1|root,COG0845@2|Bacteria,4NKUY@976|Bacteroidetes	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
WLSH2_k127_10633501_2	240292.Ava_1129	6.638e-153	509.0	COG2274@1|root,COG2274@2|Bacteria,1G2F9@1117|Cyanobacteria,1HIHN@1161|Nostocales	1117|Cyanobacteria	V	TIGRFAM NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
WLSH2_k127_10633501_6	313606.M23134_05974	3.669e-118	406.0	COG2274@1|root,COG2274@2|Bacteria,4NH0Y@976|Bacteroidetes,47U40@768503|Cytophagia	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WLSH2_k127_10633501_15	1268635.Loa_00306	1.333e-75	265.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,1RMDT@1236|Gammaproteobacteria,1JCFG@118969|Legionellales	118969|Legionellales	M	Glycosyltransferase Family 4	capM2_2	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH2_k127_10633501_7	91604.ID47_02750	1.093e-117	391.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2TSEA@28211|Alphaproteobacteria,47F26@766|Rickettsiales	766|Rickettsiales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
WLSH2_k127_10633501_10	985867.AEWF01000001_gene1815	5.33e-101	336.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,2U4AB@28211|Alphaproteobacteria,47GRB@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
WLSH2_k127_10633501_11	985867.AEWF01000001_gene1817	5.737e-101	336.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,47ETJ@766|Rickettsiales	766|Rickettsiales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
WLSH2_k127_10633501_17	985867.AEWF01000001_gene1818	2.771e-60	212.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria,47FD7@766|Rickettsiales	766|Rickettsiales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
WLSH2_k127_10633501_8	91604.ID47_02195	1.34e-116	385.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,47F51@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
WLSH2_k127_10633501_19	91604.ID47_02200	1.301e-44	169.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
WLSH2_k127_10633501_3	244582.JQAK01000001_gene2029	5.6e-150	491.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U91R@28211|Alphaproteobacteria,47FRN@766|Rickettsiales	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K01467	ko01501,ko02020,map01501,map02020	M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase
WLSH2_k127_10633501_22	997346.HMPREF9374_3180	4.44e-17	88.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,4HPRP@91061|Bacilli,27C48@186824|Thermoactinomycetaceae	91061|Bacilli	J	AKAP7 2'5' RNA ligase-like domain	ytlP	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
WLSH2_k127_10633501_24	1200792.AKYF01000006_gene1324	1.316e-07	53.0	2ETWR@1|root,33MDY@2|Bacteria,1VQ84@1239|Firmicutes,4HSAH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10633501_5	244582.JQAK01000001_gene899	9.849e-121	399.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,47F3Q@766|Rickettsiales	766|Rickettsiales	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
WLSH2_k127_10633501_0	985867.AEWF01000001_gene1876	0.0	1026.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,47EU7@766|Rickettsiales	766|Rickettsiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WLSH2_k127_10633501_23	209285.XP_006696163.1	1.232e-13	74.0	COG0271@1|root,KOG2313@2759|Eukaryota,3A8CG@33154|Opisthokonta,3P6SP@4751|Fungi,3QXAI@4890|Ascomycota,21APA@147550|Sordariomycetes,3U9QR@5139|Sordariales,3HE5D@35718|Chaetomiaceae	4751|Fungi	T	Belongs to the BolA IbaG family	uvi31	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:0106035,GO:1901564	-	ko:K22066	-	-	-	-	ko00000,ko03029	-	-	-	BolA
WLSH2_k127_10633501_18	985867.AEWF01000006_gene517	7.205e-49	181.0	COG0484@1|root,COG0484@2|Bacteria,1QU4R@1224|Proteobacteria,2TVZG@28211|Alphaproteobacteria,47FQW@766|Rickettsiales	766|Rickettsiales	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
WLSH2_k127_10633501_26	419610.Mext_3585	0.0001175	53.0	COG3021@1|root,COG3021@2|Bacteria,1MWFK@1224|Proteobacteria,2U1VS@28211|Alphaproteobacteria,1JTMW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WLSH2_k127_10633501_25	179408.Osc7112_2086	1.265e-06	51.0	COG3021@1|root,COG3021@2|Bacteria,1G1V5@1117|Cyanobacteria,1HAVR@1150|Oscillatoriales	1117|Cyanobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WLSH2_k127_10633501_14	985867.AEWF01000007_gene476	4.245e-85	291.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2TS2H@28211|Alphaproteobacteria,47FC6@766|Rickettsiales	766|Rickettsiales	M	COG1560 Lauroyl myristoyl acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
WLSH2_k127_10633501_1	91604.ID47_01880	1.177e-232	724.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,47EZQ@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
WLSH2_k127_10843958_12	414684.RC1_2738	2.661e-32	135.0	COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,2TUXK@28211|Alphaproteobacteria,2JS4K@204441|Rhodospirillales	204441|Rhodospirillales	F	Acts on guanine, xanthine and to a lesser extent hypoxanthine	gpt	-	2.4.2.22	ko:K00769	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WLSH2_k127_10843958_2	985867.AEWF01000001_gene1936	1.18e-169	540.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,47EVI@766|Rickettsiales	766|Rickettsiales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WLSH2_k127_10843958_4	985867.AEWF01000001_gene1937	3.631e-141	462.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,47F18@766|Rickettsiales	766|Rickettsiales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH2_k127_10843958_11	91604.ID47_02610	3.865e-35	138.0	2C7TH@1|root,32RJS@2|Bacteria,1MZK8@1224|Proteobacteria,2UC2R@28211|Alphaproteobacteria,47FU2@766|Rickettsiales	766|Rickettsiales	S	ETC complex I subunit conserved region	-	-	-	-	-	-	-	-	-	-	-	-	ETC_C1_NDUFA4
WLSH2_k127_10843958_9	91604.ID47_02580	2.057e-69	249.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,2TSQM@28211|Alphaproteobacteria,47FBG@766|Rickettsiales	766|Rickettsiales	J	Ribonuclease D	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WLSH2_k127_10843958_5	91604.ID47_08000	1.809e-124	406.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,47EXR@766|Rickettsiales	766|Rickettsiales	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WLSH2_k127_10843958_10	244582.JQAK01000001_gene952	5.435e-65	233.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,47FI0@766|Rickettsiales	766|Rickettsiales	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
WLSH2_k127_10843958_15	91604.ID47_11395	9.064e-22	109.0	COG0457@1|root,COG0457@2|Bacteria	91604.ID47_11395|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10843958_1	1502770.JQMG01000001_gene1691	2.488e-175	562.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,2KKTT@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
WLSH2_k127_10843958_13	334545.CCMG01000007_gene313	5.445e-26	119.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WLSH2_k127_10843958_6	91604.ID47_10900	4.415e-118	390.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,47F5F@766|Rickettsiales	766|Rickettsiales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
WLSH2_k127_10843958_7	244582.JQAK01000001_gene2119	5.414e-113	377.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,47EUY@766|Rickettsiales	766|Rickettsiales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
WLSH2_k127_10843958_8	91604.ID47_10890	7.255e-112	368.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,47F07@766|Rickettsiales	766|Rickettsiales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
WLSH2_k127_10843958_0	985867.AEWF01000004_gene57	1.787e-190	612.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,47F2S@766|Rickettsiales	766|Rickettsiales	M	Belongs to the peptidase S1C family	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_10843958_3	91604.ID47_10880	3.373e-167	554.0	COG0668@1|root,COG0668@2|Bacteria,1MY0I@1224|Proteobacteria,2TSIN@28211|Alphaproteobacteria,47FIB@766|Rickettsiales	766|Rickettsiales	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
WLSH2_k127_10843958_14	91604.ID47_09170	7.592e-22	111.0	COG3144@1|root,COG3144@2|Bacteria,1Q7AB@1224|Proteobacteria,2VDEU@28211|Alphaproteobacteria,47G4Z@766|Rickettsiales	766|Rickettsiales	N	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
WLSH2_k127_10843958_17	985867.AEWF01000002_gene1394	1.069e-06	53.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,47FT6@766|Rickettsiales	766|Rickettsiales	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD,FlgD_ig
WLSH2_k127_11137066_9	91604.ID47_03385	3.341e-47	175.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,47FG2@766|Rickettsiales	766|Rickettsiales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WLSH2_k127_11137066_2	91604.ID47_03380	3.727e-130	422.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,47F76@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	mraW	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WLSH2_k127_11137066_11	985867.AEWF01000001_gene2180	6.711e-24	109.0	COG5462@1|root,COG5462@2|Bacteria	2|Bacteria	-	-	MA20_01770	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11137066_0	985867.AEWF01000001_gene2179	1.093e-241	760.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,47EZH@766|Rickettsiales	766|Rickettsiales	M	Cell division protein FtsI penicillin-binding protein 2	pbpA2	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
WLSH2_k127_11137066_10	91604.ID47_09425	2.461e-31	128.0	2CCFX@1|root,301QQ@2|Bacteria,1PTPW@1224|Proteobacteria,2V5IZ@28211|Alphaproteobacteria,47G8Y@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11137066_8	985867.AEWF01000004_gene54	3.594e-57	205.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2TQZ1@28211|Alphaproteobacteria,47G27@766|Rickettsiales	766|Rickettsiales	S	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
WLSH2_k127_11137066_12	1198232.CYCME_2160	2.484e-15	78.0	COG1396@1|root,COG1396@2|Bacteria,1NGFD@1224|Proteobacteria,1SGW1@1236|Gammaproteobacteria,461E4@72273|Thiotrichales	72273|Thiotrichales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WLSH2_k127_11137066_6	1485545.JQLW01000005_gene1198	1.747e-84	294.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria	1224|Proteobacteria	M	protein related to capsule biosynthesis enzymes	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
WLSH2_k127_11137066_4	985867.AEWF01000001_gene2243	5.464e-86	289.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,47F8G@766|Rickettsiales	766|Rickettsiales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WLSH2_k127_11137066_3	244582.JQAK01000001_gene896	1.593e-88	298.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,47F67@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WLSH2_k127_11137066_5	91604.ID47_03040	3.057e-85	293.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,2TZY0@28211|Alphaproteobacteria,47FR5@766|Rickettsiales	766|Rickettsiales	M	Phosphatidate cytidylyltransferase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WLSH2_k127_11137066_1	244582.JQAK01000001_gene1559	3.883e-195	613.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2TS4V@28211|Alphaproteobacteria,47EUR@766|Rickettsiales	766|Rickettsiales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WLSH2_k127_11137066_7	91604.ID47_11595	3.994e-75	261.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,2U14Z@28211|Alphaproteobacteria,47G9M@766|Rickettsiales	766|Rickettsiales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WLSH2_k127_11183788_0	91604.ID47_11820	0.0	1284.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,47EX4@766|Rickettsiales	766|Rickettsiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K18138,ko:K18989	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718,M00720	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.30	-	-	ACR_tran
WLSH2_k127_11183788_1	985867.AEWF01000004_gene199	1.022e-128	426.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,47GQR@766|Rickettsiales	766|Rickettsiales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
WLSH2_k127_11183788_2	91604.ID47_10640	1.212e-126	421.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,47F0N@766|Rickettsiales	766|Rickettsiales	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
WLSH2_k127_11183788_5	91604.ID47_03525	1.784e-06	58.0	2AEUI@1|root,314RX@2|Bacteria,1PUM8@1224|Proteobacteria,2V67J@28211|Alphaproteobacteria,47G2K@766|Rickettsiales	766|Rickettsiales	S	Uncharacterized protein conserved in bacteria (DUF2125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2125
WLSH2_k127_11183788_3	985867.AEWF01000006_gene614	1.247e-95	318.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,47FBV@766|Rickettsiales	766|Rickettsiales	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH2_k127_11183788_4	4920.XP_004202696.1	1.552e-84	310.0	COG0464@1|root,KOG0741@2759|Eukaryota,38CBE@33154|Opisthokonta,3NV43@4751|Fungi,3QKQE@4890|Ascomycota,3RSNZ@4891|Saccharomycetes,47BHM@766764|Debaryomycetaceae	4751|Fungi	O	Vesicular-fusion protein SEC18	SEC18	GO:0000045,GO:0000149,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005829,GO:0005937,GO:0006810,GO:0006886,GO:0006888,GO:0006891,GO:0006892,GO:0006893,GO:0006906,GO:0006914,GO:0006996,GO:0007033,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009987,GO:0012505,GO:0015031,GO:0015833,GO:0016043,GO:0016050,GO:0016192,GO:0016236,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022406,GO:0022411,GO:0022607,GO:0030427,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033036,GO:0034613,GO:0035494,GO:0035639,GO:0036094,GO:0042144,GO:0042886,GO:0042995,GO:0043001,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043332,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0045184,GO:0046907,GO:0048193,GO:0048211,GO:0048219,GO:0048278,GO:0048280,GO:0048284,GO:0051179,GO:0051234,GO:0051286,GO:0051640,GO:0051641,GO:0051649,GO:0061024,GO:0061025,GO:0061919,GO:0061951,GO:0070300,GO:0070727,GO:0070925,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0072659,GO:0090150,GO:0090174,GO:0097159,GO:0097367,GO:0097576,GO:0098876,GO:0120025,GO:0120038,GO:0140056,GO:1901265,GO:1901363,GO:1905037,GO:1990778	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA,CDC48_2,CDC48_N
WLSH2_k127_11228938_8	91604.ID47_01675	1.583e-54	198.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,47FIA@766|Rickettsiales	766|Rickettsiales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WLSH2_k127_11228938_9	244582.JQAK01000001_gene891	2.342e-44	168.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,47FHR@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WLSH2_k127_11228938_1	91604.ID47_08335	9.483e-229	713.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2TS3R@28211|Alphaproteobacteria,47F36@766|Rickettsiales	766|Rickettsiales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WLSH2_k127_11228938_0	91604.ID47_08330	0.0	1242.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,47EV7@766|Rickettsiales	766|Rickettsiales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WLSH2_k127_11228938_7	244582.JQAK01000004_gene237	2.94e-75	258.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,47FJV@766|Rickettsiales	766|Rickettsiales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WLSH2_k127_11228938_6	985867.AEWF01000001_gene2022	6.291e-108	357.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,47FVN@766|Rickettsiales	766|Rickettsiales	E	HMGL-like	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
WLSH2_k127_11228938_5	264202.CF0427	4.469e-126	413.0	COG0516@1|root,COG0516@2|Bacteria,2JH39@204428|Chlamydiae	204428|Chlamydiae	C	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
WLSH2_k127_11228938_2	1500890.JQNL01000001_gene121	5.32e-198	629.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1X2YI@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
WLSH2_k127_11228938_4	626887.J057_05881	2.578e-145	473.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,465K9@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	-	-	3.5.4.28,3.5.4.3,3.5.4.31	ko:K01487,ko:K12960	ko00230,ko00270,ko01100,map00230,map00270,map01100	-	R01676,R09660	RC00204,RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WLSH2_k127_11228938_3	1094715.CM001373_gene3054	1.439e-174	567.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1JCWM@118969|Legionellales	118969|Legionellales	P	E1-E2 ATPase	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH2_k127_11277634_1	985867.AEWF01000002_gene1443	1.844e-121	398.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,47F79@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
WLSH2_k127_11277634_4	570417.WP0261	2.762e-16	79.0	COG1672@1|root,COG1672@2|Bacteria,1MWJX@1224|Proteobacteria,2V4HQ@28211|Alphaproteobacteria,47FYU@766|Rickettsiales	766|Rickettsiales	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
WLSH2_k127_11277634_3	292805.Wbm0116	2.588e-16	81.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,APH,TIR_2
WLSH2_k127_11277634_2	765952.PUV_16110	7.385e-72	249.0	COG1672@1|root,COG1672@2|Bacteria,2JGKE@204428|Chlamydiae	204428|Chlamydiae	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,HTH_5
WLSH2_k127_11277634_5	342949.PNA2_0984	1.685e-10	66.0	COG1672@1|root,arCOG03166@2157|Archaea,2Y2SA@28890|Euryarchaeota,245CF@183968|Thermococci	183968|Thermococci	S	AAA ATPase domain	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
WLSH2_k127_11277634_0	244582.JQAK01000004_gene333	1.545e-272	852.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,47F4S@766|Rickettsiales	766|Rickettsiales	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WLSH2_k127_11319858_21	1304866.K413DRAFT_0395	4.44e-40	151.0	COG3911@1|root,COG3911@2|Bacteria,1USSP@1239|Firmicutes,24ZQP@186801|Clostridia,36R5U@31979|Clostridiaceae	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
WLSH2_k127_11319858_20	639030.JHVA01000001_gene3382	1.992e-52	199.0	COG1680@1|root,COG1680@2|Bacteria,3Y3WB@57723|Acidobacteria,2JJDH@204432|Acidobacteriia	204432|Acidobacteriia	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WLSH2_k127_11319858_26	1448139.AI20_14240	1.984e-22	109.0	COG0457@1|root,COG0457@2|Bacteria,1P0WK@1224|Proteobacteria,1SU5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
WLSH2_k127_11319858_8	985867.AEWF01000003_gene862	2.248e-114	379.0	COG4188@1|root,COG4188@2|Bacteria,1N436@1224|Proteobacteria,2UF08@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
WLSH2_k127_11319858_4	1230343.CANP01000031_gene2518	3.187e-180	576.0	COG0488@1|root,COG0488@2|Bacteria,1R6WQ@1224|Proteobacteria,1S1SH@1236|Gammaproteobacteria,1JCS9@118969|Legionellales	118969|Legionellales	S	ABC transporter, ATP-binding protein	uup_2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_11319858_6	1230343.CANP01000041_gene3068	1.085e-132	430.0	COG3173@1|root,COG3173@2|Bacteria,1R5VZ@1224|Proteobacteria,1SMQY@1236|Gammaproteobacteria,1JDMV@118969|Legionellales	118969|Legionellales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_11319858_12	1122169.AREN01000024_gene2471	4.866e-89	298.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,1S5BY@1236|Gammaproteobacteria,1JD0R@118969|Legionellales	118969|Legionellales	S	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_SAD
WLSH2_k127_11319858_19	658187.LDG_7092	6.979e-56	199.0	COG0262@1|root,COG0262@2|Bacteria,1RH02@1224|Proteobacteria,1SA43@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	RibD C-terminal domain	FolA	-	-	-	-	-	-	-	-	-	-	-	RibD_C
WLSH2_k127_11319858_2	244581.IM40_02205	5.588e-215	711.0	COG0507@1|root,COG0507@2|Bacteria,1MUTR@1224|Proteobacteria,2TSQQ@28211|Alphaproteobacteria,47EZN@766|Rickettsiales	766|Rickettsiales	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,MobA_MobL
WLSH2_k127_11319858_27	91604.ID47_07410	1.702e-12	73.0	2CG76@1|root,301UK@2|Bacteria,1PTYR@1224|Proteobacteria,2V5S0@28211|Alphaproteobacteria,47GB3@766|Rickettsiales	766|Rickettsiales	S	Conjugal transfer protein TraD	-	-	-	-	-	-	-	-	-	-	-	-	TraD
WLSH2_k127_11319858_9	1411685.U062_00608	3.759e-113	377.0	COG2253@1|root,COG2253@2|Bacteria,1R66E@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	ko:K09144	-	-	-	-	ko00000	-	-	-	AbiEii,WYL
WLSH2_k127_11319858_15	1411685.U062_00609	2.508e-73	255.0	COG5340@1|root,COG5340@2|Bacteria,1RDP9@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
WLSH2_k127_11319858_5	244581.IM40_08105	1.766e-135	441.0	COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,2TS7K@28211|Alphaproteobacteria,47GQA@766|Rickettsiales	766|Rickettsiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
WLSH2_k127_11319858_30	244581.IM40_07805	0.0004929	49.0	COG3903@1|root,COG3903@2|Bacteria,1Q7EE@1224|Proteobacteria,2VDJE@28211|Alphaproteobacteria,47GDG@766|Rickettsiales	766|Rickettsiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
WLSH2_k127_11319858_11	91464.S7335_1012	4.481e-90	313.0	COG3464@1|root,COG3464@2|Bacteria,1G377@1117|Cyanobacteria,1H3U4@1129|Synechococcus	1117|Cyanobacteria	L	L COG3436 Transposase and inactivated derivatives	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
WLSH2_k127_11319858_0	227377.CBU_1928	4.305e-280	889.0	COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1JCGB@118969|Legionellales	118969|Legionellales	IQ	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
WLSH2_k127_11319858_23	648757.Rvan_1665	5.272e-25	110.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,3N8XA@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH2_k127_11319858_24	244582.JQAK01000001_gene893	2.977e-23	107.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,47FMT@766|Rickettsiales	766|Rickettsiales	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH2_k127_11319858_13	1333998.M2A_2770	1.209e-88	301.0	COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria,4BT7P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.163,1.1.1.53	ko:K00038,ko:K17754	ko00140,ko00930,ko01100,map00140,map00930,map01100	-	R02229,R04831,R04834,R04844,R04847	RC00139,RC00144,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WLSH2_k127_11319858_3	1132855.KB913035_gene1501	5.936e-212	688.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,2KM34@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Cation transporter/ATPase, N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH2_k127_11319858_28	768671.ThimaDRAFT_4913	1.157e-10	63.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_11319858_17	622637.KE124774_gene1190	1.106e-69	251.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,2UB2Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11319858_25	1187851.A33M_2779	1.321e-22	108.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_11319858_22	244581.IM40_03000	1.182e-25	113.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2UB7Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
WLSH2_k127_11319858_10	1173024.KI912148_gene3334	1.277e-112	374.0	COG2843@1|root,COG2843@2|Bacteria,1G20Q@1117|Cyanobacteria,1JJC3@1189|Stigonemataceae	1117|Cyanobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
WLSH2_k127_11319858_14	886293.Sinac_3852	1.364e-78	269.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K07100	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
WLSH2_k127_11319858_18	91604.ID47_02045	3.826e-63	239.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
WLSH2_k127_11319858_1	91604.ID47_02040	1.094e-247	777.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,47F2D@766|Rickettsiales	766|Rickettsiales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WLSH2_k127_11319858_16	765913.ThidrDRAFT_2496	6.374e-70	251.0	COG0628@1|root,COG0628@2|Bacteria,1NG06@1224|Proteobacteria,1S1I3@1236|Gammaproteobacteria,1WXUK@135613|Chromatiales	135613|Chromatiales	S	Transmembrane protein 43	-	-	-	-	-	-	-	-	-	-	-	-	TMEM43
WLSH2_k127_11319858_29	946483.Cenrod_1741	4.21e-09	60.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2VNF8@28216|Betaproteobacteria,4AG4P@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_11319858_7	985867.AEWF01000002_gene1332	1.779e-122	400.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2TRZ5@28211|Alphaproteobacteria,47FAX@766|Rickettsiales	766|Rickettsiales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
WLSH2_k127_11451104_11	555779.Dthio_PD0022	1.317e-53	195.0	COG4974@1|root,COG4974@2|Bacteria,1RC0C@1224|Proteobacteria,42W1W@68525|delta/epsilon subdivisions,2WRTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
WLSH2_k127_11451104_10	555779.Dthio_PD0022	2.711e-71	248.0	COG4974@1|root,COG4974@2|Bacteria,1RC0C@1224|Proteobacteria,42W1W@68525|delta/epsilon subdivisions,2WRTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
WLSH2_k127_11451104_14	1034943.BN1094_01081	3.472e-39	154.0	COG3436@1|root,COG3436@2|Bacteria,1N638@1224|Proteobacteria,1SFHC@1236|Gammaproteobacteria,1JFES@118969|Legionellales	118969|Legionellales	L	IS66 Orf2 like protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
WLSH2_k127_11451104_21	1034943.BN1094_01080	0.0006758	48.0	2APVY@1|root,31F0F@2|Bacteria,1QCDI@1224|Proteobacteria,1T83G@1236|Gammaproteobacteria,1JG7Q@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11451104_15	575586.HMPREF0016_00598	6.687e-38	145.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SAT7@1236|Gammaproteobacteria,3NNGV@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_11451104_9	985867.AEWF01000001_gene2103	2.907e-87	293.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,47FAN@766|Rickettsiales	766|Rickettsiales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WLSH2_k127_11451104_2	985867.AEWF01000001_gene2102	2.551e-151	490.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,47F0C@766|Rickettsiales	766|Rickettsiales	M	Belongs to the peptidase S11 family	dacA	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
WLSH2_k127_11451104_6	244582.JQAK01000001_gene1212	3.383e-102	344.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2TUER@28211|Alphaproteobacteria,47FIP@766|Rickettsiales	766|Rickettsiales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
WLSH2_k127_11451104_13	244582.JQAK01000001_gene1061	3.513e-44	179.0	COG2861@1|root,COG2861@2|Bacteria	2|Bacteria	M	carbohydrate metabolic process	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
WLSH2_k127_11451104_3	331113.SNE_A05360	2.473e-136	449.0	COG1672@1|root,COG1672@2|Bacteria,2JGKE@204428|Chlamydiae	204428|Chlamydiae	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,HTH_5
WLSH2_k127_11451104_1	91604.ID47_06770	1.141e-163	520.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,47EZ4@766|Rickettsiales	766|Rickettsiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_11451104_7	91604.ID47_10205	4.579e-99	333.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2TQTF@28211|Alphaproteobacteria,47FVW@766|Rickettsiales	766|Rickettsiales	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
WLSH2_k127_11451104_4	244582.JQAK01000001_gene1062	1.216e-122	404.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,47F3J@766|Rickettsiales	766|Rickettsiales	M	Belongs to the peptidase S41A family	ctp	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WLSH2_k127_11451104_8	244582.JQAK01000001_gene1079	5.956e-92	306.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,47F9F@766|Rickettsiales	766|Rickettsiales	L	hmm pf01612	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
WLSH2_k127_11451104_16	96561.Dole_1700	7.383e-32	126.0	COG4115@1|root,COG4115@2|Bacteria,1MZBP@1224|Proteobacteria,42V0Y@68525|delta/epsilon subdivisions,2WRCR@28221|Deltaproteobacteria,2MMBJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	TIGRFAM addiction module toxin, Txe YoeB family	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
WLSH2_k127_11451104_17	266265.Bxe_B1841	1.938e-13	73.0	COG2161@1|root,COG2161@2|Bacteria,1N6X6@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	yefM	-	-	ko:K19159	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
WLSH2_k127_11451104_5	91604.ID47_06905	1.685e-107	359.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,47F6H@766|Rickettsiales	766|Rickettsiales	L	Belongs to the 'phage' integrase family	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WLSH2_k127_11451104_18	1122179.KB890439_gene1605	1.46e-07	65.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1INME@117747|Sphingobacteriia	976|Bacteroidetes	O	Peptidase S8 and S53 subtilisin kexin sedolisin	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH2_k127_11451104_0	1279038.KB907337_gene394	1.239e-226	723.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,2JPJU@204441|Rhodospirillales	204441|Rhodospirillales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WLSH2_k127_11451104_12	985867.AEWF01000001_gene1780	6.067e-48	173.0	2DPV5@1|root,333HH@2|Bacteria,1NCA9@1224|Proteobacteria,2UHMY@28211|Alphaproteobacteria,47FF4@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1252386_2	1437425.CSEC_1461	9.483e-42	166.0	COG4188@1|root,COG4188@2|Bacteria,2JH8N@204428|Chlamydiae	204428|Chlamydiae	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1252386_0	91604.ID47_11040	3.944e-128	414.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2TS3H@28211|Alphaproteobacteria,47F2X@766|Rickettsiales	766|Rickettsiales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
WLSH2_k127_1252386_1	1528098.NOVO_05390	6.02e-120	396.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,47EZB@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_1269271_4	244582.JQAK01000001_gene676	1.254e-155	507.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,47ESZ@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH2_k127_1269271_8	91604.ID47_06015	1.795e-26	109.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria,47FT5@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
WLSH2_k127_1269271_2	1207063.P24_17695	3.299e-173	562.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TQXN@28211|Alphaproteobacteria,2JQSS@204441|Rhodospirillales	204441|Rhodospirillales	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
WLSH2_k127_1269271_7	1209072.ALBT01000053_gene487	2.918e-38	147.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_1269271_1	244581.IM40_08080	8.192e-176	563.0	COG1672@1|root,COG1672@2|Bacteria,1MWJX@1224|Proteobacteria,2V4HQ@28211|Alphaproteobacteria,47FYU@766|Rickettsiales	766|Rickettsiales	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
WLSH2_k127_1269271_0	91604.ID47_11640	9.114e-267	841.0	COG2114@1|root,COG2114@2|Bacteria,1RBTC@1224|Proteobacteria,2TV5V@28211|Alphaproteobacteria,47F19@766|Rickettsiales	766|Rickettsiales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,dCache_1
WLSH2_k127_1269271_3	91604.ID47_11645	1.41e-158	517.0	COG2860@1|root,COG2860@2|Bacteria,1QVY0@1224|Proteobacteria,2UB1W@28211|Alphaproteobacteria,47F2R@766|Rickettsiales	766|Rickettsiales	S	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3,UPF0126
WLSH2_k127_1269271_5	658187.LDG_7099	2.043e-101	333.0	COG0110@1|root,COG0110@2|Bacteria,1MUCJ@1224|Proteobacteria,1RPPT@1236|Gammaproteobacteria,1JE38@118969|Legionellales	118969|Legionellales	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.28	ko:K00638	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Hexapep
WLSH2_k127_1269271_6	91604.ID47_10615	1.795e-54	195.0	COG3708@1|root,COG3708@2|Bacteria,1RK32@1224|Proteobacteria,2UBD7@28211|Alphaproteobacteria,47F9B@766|Rickettsiales	766|Rickettsiales	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2
WLSH2_k127_1432414_8	686340.Metal_1232	8.232e-09	58.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SA4A@1236|Gammaproteobacteria,1XFUA@135618|Methylococcales	135618|Methylococcales	L	Protein of unknown function (DUF559)	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
WLSH2_k127_1432414_9	575586.HMPREF0016_00598	0.0002559	44.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SAT7@1236|Gammaproteobacteria,3NNGV@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_1432414_3	1303518.CCALI_01155	7.476e-115	379.0	COG1064@1|root,COG1064@2|Bacteria	2|Bacteria	P	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_1432414_4	91604.ID47_09605	5.973e-99	327.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria,47FFE@766|Rickettsiales	766|Rickettsiales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
WLSH2_k127_1432414_0	91604.ID47_09610	5.719e-253	792.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,47EXM@766|Rickettsiales	766|Rickettsiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WLSH2_k127_1432414_5	91604.ID47_09615	2.537e-32	126.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,47FRG@766|Rickettsiales	766|Rickettsiales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WLSH2_k127_1432414_6	985867.AEWF01000003_gene931	4.053e-25	110.0	COG0594@1|root,COG0594@2|Bacteria	2|Bacteria	J	ribonuclease P activity	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WLSH2_k127_1432414_7	426117.M446_5079	2.048e-16	79.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2UJCE@28211|Alphaproteobacteria,1JW3Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
WLSH2_k127_1432414_2	244582.JQAK01000003_gene428	6.088e-130	424.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
WLSH2_k127_1432414_1	244582.JQAK01000001_gene829	1.194e-191	606.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TTXA@28211|Alphaproteobacteria,47FXT@766|Rickettsiales	766|Rickettsiales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WLSH2_k127_1447716_7	985867.AEWF01000001_gene1895	3.706e-143	494.0	COG2911@1|root,COG2911@2|Bacteria,1PQT9@1224|Proteobacteria,2V8PC@28211|Alphaproteobacteria,47G3B@766|Rickettsiales	766|Rickettsiales	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	-	-	-	-	-	-	-	-	-	TamB
WLSH2_k127_1447716_6	985867.AEWF01000001_gene1896	9.084e-148	491.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2TRWD@28211|Alphaproteobacteria,47FVR@766|Rickettsiales	766|Rickettsiales	M	Surface antigen	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag
WLSH2_k127_1447716_10	244582.JQAK01000001_gene1029	1.221e-73	250.0	COG1846@1|root,COG1846@2|Bacteria,1RA1V@1224|Proteobacteria,2U5W6@28211|Alphaproteobacteria,47FI9@766|Rickettsiales	766|Rickettsiales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
WLSH2_k127_1447716_21	326298.Suden_1198	4.048e-06	61.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42SUS@68525|delta/epsilon subdivisions,2YQB0@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	NifU,Sel1
WLSH2_k127_1447716_19	159749.K0T2T3	1.376e-12	82.0	COG0790@1|root,KOG1550@2759|Eukaryota	2759|Eukaryota	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
WLSH2_k127_1447716_17	452471.Aasi_0854	1.299e-17	98.0	COG0790@1|root,COG0790@2|Bacteria,4NMCC@976|Bacteroidetes,47QS2@768503|Cytophagia	976|Bacteroidetes	KLT	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Pkinase,Sel1,Tox-ODYAM1,U-box
WLSH2_k127_1447716_11	588596.U9SRH9	6.545e-68	265.0	COG0790@1|root,KOG1550@2759|Eukaryota	588596.U9SRH9|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1447716_18	90675.XP_010475540.1	5.93e-17	97.0	COG0666@1|root,KOG0504@2759|Eukaryota,37HUN@33090|Viridiplantae,3G7GD@35493|Streptophyta,3HRMK@3699|Brassicales	35493|Streptophyta	S	Domain of unknown function	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005886,GO:0012505,GO:0016020,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4,PGG
WLSH2_k127_1447716_20	177437.HRM2_25390	8.066e-07	51.0	COG4467@1|root,COG4467@2|Bacteria,1QW8C@1224|Proteobacteria	1224|Proteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
WLSH2_k127_1447716_12	91604.ID47_09280	2.463e-59	217.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,47FG6@766|Rickettsiales	766|Rickettsiales	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WLSH2_k127_1447716_1	163164.WD_0740	2.235e-228	714.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2TQMA@28211|Alphaproteobacteria,47F4N@766|Rickettsiales	766|Rickettsiales	C	COG1271 Cytochrome bd-type quinol oxidase, subunit 1	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
WLSH2_k127_1447716_4	1333998.M2A_0859	9.902e-170	542.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,4BR9P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome bd terminal oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
WLSH2_k127_1447716_13	1522072.IL54_3053	3.317e-49	185.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria,2K1HH@204457|Sphingomonadales	204457|Sphingomonadales	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTP_transferase
WLSH2_k127_1447716_9	244582.JQAK01000001_gene2160	1.54e-88	303.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,47FEG@766|Rickettsiales	766|Rickettsiales	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
WLSH2_k127_1447716_8	91604.ID47_08175	6.763e-101	335.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,47FF7@766|Rickettsiales	766|Rickettsiales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
WLSH2_k127_1447716_2	91604.ID47_08180	1.879e-226	710.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,47F12@766|Rickettsiales	766|Rickettsiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WLSH2_k127_1447716_23	1449050.JNLE01000003_gene2641	0.0002993	55.0	COG3675@1|root,COG3675@2|Bacteria,1UUQ8@1239|Firmicutes,257FI@186801|Clostridia	186801|Clostridia	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
WLSH2_k127_1447716_16	227086.JGI_V11_20443	1.57e-38	158.0	COG4886@1|root,KOG0619@2759|Eukaryota	2759|Eukaryota	U	regulation of response to stimulus	-	-	-	ko:K19613	ko04014,map04014	-	-	-	ko00000,ko00001	-	-	-	COR,LRR_1,LRR_4,LRR_8,Peptidase_C14,Roc,U-box
WLSH2_k127_1447716_5	244582.JQAK01000001_gene1726	1.263e-153	493.0	COG1114@1|root,COG1114@2|Bacteria,1MVIF@1224|Proteobacteria,2UTUU@28211|Alphaproteobacteria,47FX2@766|Rickettsiales	766|Rickettsiales	E	Branched-chain amino acid transport protein	-	-	-	ko:K03311	-	-	-	-	ko00000	2.A.26	-	-	Branch_AA_trans
WLSH2_k127_1447716_0	985867.AEWF01000002_gene1663	1.172e-306	945.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,47EV8@766|Rickettsiales	766|Rickettsiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groEL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WLSH2_k127_1447716_15	985867.AEWF01000002_gene1662	3.22e-47	170.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria,47FG0@766|Rickettsiales	766|Rickettsiales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WLSH2_k127_1447716_3	91604.ID47_02000	1.452e-191	604.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,47EVG@766|Rickettsiales	766|Rickettsiales	E	Aminotransferase	aatA	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_1447716_14	91604.ID47_09545	2.838e-48	181.0	28PJ2@1|root,33FKF@2|Bacteria,1NIFN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1449565_4	91604.ID47_08770	2.854e-99	326.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,47EVT@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH2_k127_1449565_2	244582.JQAK01000001_gene2084	2.758e-142	458.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,47F3W@766|Rickettsiales	766|Rickettsiales	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
WLSH2_k127_1449565_11	1282362.AEAC466_00060	2.144e-36	144.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,2KGPK@204458|Caulobacterales	204458|Caulobacterales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
WLSH2_k127_1449565_3	244582.JQAK01000001_gene2086	5.816e-106	350.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,47FC1@766|Rickettsiales	766|Rickettsiales	S	COG1253 Hemolysins and related proteins containing CBS domains	tlyC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
WLSH2_k127_1449565_5	91604.ID47_02495	5.034e-90	304.0	COG1464@1|root,COG1464@2|Bacteria,1MUVY@1224|Proteobacteria,2TRCJ@28211|Alphaproteobacteria,47G2B@766|Rickettsiales	766|Rickettsiales	P	NLPA lipoprotein	-	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
WLSH2_k127_1449565_0	244582.JQAK01000001_gene2009	0.0	1016.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,47EZM@766|Rickettsiales	766|Rickettsiales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WLSH2_k127_1449565_1	414684.RC1_2859	4.991e-152	489.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2JQ3U@204441|Rhodospirillales	204441|Rhodospirillales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH2_k127_1449565_6	244582.JQAK01000001_gene2011	9.154e-66	233.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,47F9P@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
WLSH2_k127_1449565_14	91604.ID47_01335	2.084e-12	67.0	COG2026@1|root,COG2026@2|Bacteria,1N76D@1224|Proteobacteria,2UF77@28211|Alphaproteobacteria	28211|Alphaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
WLSH2_k127_1449565_15	91604.ID47_02215	0.000249	53.0	2ARNV@1|root,31GZK@2|Bacteria,1QEP0@1224|Proteobacteria,2V5U3@28211|Alphaproteobacteria,47GCJ@766|Rickettsiales	91604.ID47_02215|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1449565_7	981369.JQMJ01000004_gene2263	4.71e-51	183.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria,2NHYR@228398|Streptacidiphilus	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_3,SnoaL_2
WLSH2_k127_1449565_9	91604.ID47_10105	6.018e-43	169.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,2TSNZ@28211|Alphaproteobacteria,47G1A@766|Rickettsiales	766|Rickettsiales	P	Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
WLSH2_k127_1449565_10	269796.Rru_A3354	1.848e-39	156.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,2JS6Z@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WLSH2_k127_1449565_12	32507.XP_006801226.1	7.176e-17	93.0	COG4826@1|root,KOG2392@2759|Eukaryota,38E87@33154|Opisthokonta,3BEDG@33208|Metazoa,3CW32@33213|Bilateria,481ZQ@7711|Chordata,48YRQ@7742|Vertebrata,49XU3@7898|Actinopterygii	33208|Metazoa	V	Serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	SERPINE2	GO:0000003,GO:0001558,GO:0002028,GO:0003006,GO:0003008,GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005102,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006950,GO:0006996,GO:0007162,GO:0007275,GO:0007320,GO:0007399,GO:0007417,GO:0007420,GO:0007565,GO:0007566,GO:0007596,GO:0007599,GO:0007600,GO:0007610,GO:0007617,GO:0007618,GO:0007620,GO:0008150,GO:0008201,GO:0008285,GO:0008589,GO:0009314,GO:0009581,GO:0009582,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009653,GO:0009888,GO:0009892,GO:0009894,GO:0009895,GO:0009897,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010256,GO:0010466,GO:0010468,GO:0010543,GO:0010544,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010720,GO:0010755,GO:0010757,GO:0010766,GO:0010951,GO:0010955,GO:0010959,GO:0010975,GO:0010976,GO:0012505,GO:0014013,GO:0014015,GO:0014066,GO:0014067,GO:0016020,GO:0016043,GO:0016050,GO:0019098,GO:0019222,GO:0019897,GO:0019898,GO:0019953,GO:0021549,GO:0021575,GO:0021587,GO:0021675,GO:0021681,GO:0021683,GO:0021695,GO:0021696,GO:0022008,GO:0022037,GO:0022407,GO:0022408,GO:0022414,GO:0023051,GO:0023056,GO:0023057,GO:0030141,GO:0030154,GO:0030155,GO:0030162,GO:0030193,GO:0030195,GO:0030234,GO:0030308,GO:0030334,GO:0030414,GO:0030902,GO:0031012,GO:0031091,GO:0031232,GO:0031323,GO:0031324,GO:0031344,GO:0031346,GO:0031410,GO:0031594,GO:0031982,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0032940,GO:0033363,GO:0034110,GO:0034111,GO:0035295,GO:0036477,GO:0040008,GO:0040012,GO:0040034,GO:0042060,GO:0042127,GO:0042176,GO:0042177,GO:0042628,GO:0043025,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043269,GO:0043271,GO:0044085,GO:0044092,GO:0044297,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044703,GO:0044706,GO:0045202,GO:0045297,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045685,GO:0045687,GO:0045861,GO:0045879,GO:0045926,GO:0046903,GO:0048167,GO:0048505,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048608,GO:0048609,GO:0048699,GO:0048710,GO:0048711,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050804,GO:0050806,GO:0050817,GO:0050818,GO:0050819,GO:0050865,GO:0050866,GO:0050877,GO:0050878,GO:0050896,GO:0050906,GO:0050954,GO:0050974,GO:0050982,GO:0051049,GO:0051051,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051270,GO:0051336,GO:0051346,GO:0051606,GO:0051704,GO:0051960,GO:0051962,GO:0051966,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060291,GO:0060322,GO:0060384,GO:0060429,GO:0061041,GO:0061045,GO:0061107,GO:0061108,GO:0061110,GO:0061134,GO:0061135,GO:0061458,GO:0062023,GO:0065007,GO:0065008,GO:0065009,GO:0070613,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0090330,GO:0090331,GO:0097367,GO:0097458,GO:0097708,GO:0098552,GO:0098772,GO:0099177,GO:0099503,GO:0120035,GO:1900046,GO:1900047,GO:1901681,GO:1902531,GO:1902532,GO:1903034,GO:1903035,GO:1903317,GO:1903318,GO:2000026,GO:2000145	-	ko:K16643	-	-	-	-	ko00000,ko00536	-	-	-	Serpin
WLSH2_k127_1449565_8	244581.IM40_08080	4.299e-47	173.0	COG1672@1|root,COG1672@2|Bacteria,1MWJX@1224|Proteobacteria,2V4HQ@28211|Alphaproteobacteria,47FYU@766|Rickettsiales	766|Rickettsiales	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
WLSH2_k127_1499747_20	199310.c5383	5.401e-05	46.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1Q7PK@1224|Proteobacteria,1SPCH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
WLSH2_k127_1499747_1	91604.ID47_10000	1.652e-279	873.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2TRND@28211|Alphaproteobacteria,47FW4@766|Rickettsiales	766|Rickettsiales	I	AMP-binding enzyme	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding
WLSH2_k127_1499747_0	91604.ID47_06010	0.0	1724.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2TSY0@28211|Alphaproteobacteria,47F0D@766|Rickettsiales	766|Rickettsiales	S	ImcF-related N-terminal domain	-	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	ImcF-related_N
WLSH2_k127_1499747_8	244582.JQAK01000001_gene1176	5.044e-89	301.0	COG3455@1|root,COG3455@2|Bacteria,1N723@1224|Proteobacteria,2UM9J@28211|Alphaproteobacteria,47FQ2@766|Rickettsiales	766|Rickettsiales	S	Type VI secretion system protein DotU	-	-	-	-	-	-	-	-	-	-	-	-	DotU
WLSH2_k127_1499747_3	91604.ID47_06000	2.255e-182	582.0	COG3522@1|root,COG3522@2|Bacteria,1PNFP@1224|Proteobacteria,2VD65@28211|Alphaproteobacteria,47FBE@766|Rickettsiales	766|Rickettsiales	S	Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE	-	-	-	ko:K11893	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_VasE
WLSH2_k127_1499747_17	765913.ThidrDRAFT_2829	6.451e-19	90.0	2ANY6@1|root,31DZ3@2|Bacteria,1RIZN@1224|Proteobacteria,1S77G@1236|Gammaproteobacteria,1X0TD@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4280)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4280
WLSH2_k127_1499747_9	985867.AEWF01000001_gene2085	1.288e-86	301.0	COG3515@1|root,COG3515@2|Bacteria,1MY80@1224|Proteobacteria,2UFDW@28211|Alphaproteobacteria,47FE8@766|Rickettsiales	766|Rickettsiales	S	ImpA, N-terminal, type VI secretion system	-	-	-	ko:K11902	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	ImpA_N
WLSH2_k127_1499747_18	7994.ENSAMXP00000018515	1.317e-14	81.0	COG4886@1|root,KOG0619@2759|Eukaryota,39TPF@33154|Opisthokonta,3BEWQ@33208|Metazoa,3CWJ8@33213|Bilateria,47ZET@7711|Chordata,48VJ3@7742|Vertebrata,49RFZ@7898|Actinopterygii	33208|Metazoa	S	Leucine rich repeat containing 39	LRRC39	GO:0003007,GO:0003008,GO:0003013,GO:0003015,GO:0006996,GO:0007010,GO:0007275,GO:0007507,GO:0007517,GO:0008015,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010927,GO:0014706,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0031032,GO:0032501,GO:0032502,GO:0032989,GO:0042692,GO:0044085,GO:0045214,GO:0048468,GO:0048513,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048856,GO:0048869,GO:0051146,GO:0055001,GO:0055002,GO:0055008,GO:0060047,GO:0060415,GO:0060537,GO:0061061,GO:0070925,GO:0071840,GO:0072359,GO:0097435	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8
WLSH2_k127_1499747_7	985867.AEWF01000002_gene1445	4.822e-115	380.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,47F6Z@766|Rickettsiales	766|Rickettsiales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
WLSH2_k127_1499747_6	91604.ID47_00290	4.467e-118	386.0	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,2TUBR@28211|Alphaproteobacteria,47FH0@766|Rickettsiales	766|Rickettsiales	S	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	MTS
WLSH2_k127_1499747_19	985867.AEWF01000004_gene169	1.805e-14	86.0	2AE3H@1|root,313WN@2|Bacteria,1PT6Y@1224|Proteobacteria,2V546@28211|Alphaproteobacteria,47G5Y@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1499747_12	91604.ID47_11245	3.55e-74	262.0	COG3621@1|root,COG3621@2|Bacteria,1NEE4@1224|Proteobacteria,2V0HM@28211|Alphaproteobacteria,47G11@766|Rickettsiales	766|Rickettsiales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WLSH2_k127_1499747_11	1041139.KB902591_gene550	4.46e-79	271.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,4B79P@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WLSH2_k127_1499747_5	985867.AEWF01000001_gene2177	5.284e-148	472.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,47EVR@766|Rickettsiales	766|Rickettsiales	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WLSH2_k127_1499747_10	91604.ID47_04215	4.029e-80	271.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,47FDB@766|Rickettsiales	766|Rickettsiales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WLSH2_k127_1499747_16	91604.ID47_11715	8.315e-34	132.0	COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,47FMB@766|Rickettsiales	766|Rickettsiales	S	Uncharacterized protein conserved in bacteria (DUF2312)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2312
WLSH2_k127_1499747_2	985867.AEWF01000002_gene1341	2.261e-221	697.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,47FAJ@766|Rickettsiales	766|Rickettsiales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
WLSH2_k127_1499747_13	485913.Krac_2228	1.47e-73	259.0	COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WLSH2_k127_1499747_14	985867.AEWF01000001_gene2026	8.484e-63	222.0	COG2964@1|root,COG2964@2|Bacteria,1RBFW@1224|Proteobacteria,2U5B8@28211|Alphaproteobacteria,47GGD@766|Rickettsiales	766|Rickettsiales	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
WLSH2_k127_1499747_4	985867.AEWF01000001_gene2025	9.076e-162	517.0	COG0436@1|root,COG0436@2|Bacteria,1PEQR@1224|Proteobacteria,2V7WB@28211|Alphaproteobacteria,47GBS@766|Rickettsiales	766|Rickettsiales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WLSH2_k127_1499747_15	765952.PUV_14860	2.174e-56	208.0	COG2423@1|root,COG2423@2|Bacteria,2JGMU@204428|Chlamydiae	204428|Chlamydiae	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
WLSH2_k127_1501148_9	1120999.JONM01000027_gene480	1.145e-79	300.0	COG2304@1|root,COG2931@1|root,COG4932@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2VKA9@28216|Betaproteobacteria,2KR3Z@206351|Neisseriales	206351|Neisseriales	Q	TIGRFAM outer membrane adhesin like proteiin	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
WLSH2_k127_1501148_3	716544.wcw_1773	7.806e-133	433.0	COG1373@1|root,COG1373@2|Bacteria,2JGTG@204428|Chlamydiae	204428|Chlamydiae	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_1501148_2	1122604.JONR01000043_gene3174	1.593e-136	441.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1X3XQ@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
WLSH2_k127_1501148_7	1382230.ASAP_0816	5.35e-99	335.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TTAK@28211|Alphaproteobacteria,2JPCZ@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_1501148_12	244582.JQAK01000001_gene948	1.223e-29	118.0	COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UC58@28211|Alphaproteobacteria,47FPN@766|Rickettsiales	766|Rickettsiales	J	ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WLSH2_k127_1501148_5	5786.XP_003294959.1	4.625e-115	380.0	29VBM@1|root,2RXKM@2759|Eukaryota,3XAYF@554915|Amoebozoa	554915|Amoebozoa	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1501148_10	244582.JQAK01000001_gene2027	7.634e-62	222.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,47FBZ@766|Rickettsiales	766|Rickettsiales	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WLSH2_k127_1501148_13	985867.AEWF01000003_gene892	2.222e-21	99.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2,Response_reg
WLSH2_k127_1501148_6	985867.AEWF01000003_gene891	6.515e-109	361.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,47FWZ@766|Rickettsiales	766|Rickettsiales	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
WLSH2_k127_1501148_4	244582.JQAK01000001_gene2023	1.155e-117	387.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2TQVX@28211|Alphaproteobacteria,47F3A@766|Rickettsiales	766|Rickettsiales	L	NUDIX domain	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
WLSH2_k127_1501148_8	91604.ID47_03470	3.473e-83	288.0	COG0063@1|root,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria,47GN2@766|Rickettsiales	766|Rickettsiales	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
WLSH2_k127_1501148_17	192875.XP_004343590.1	4.335e-09	68.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38EHF@33154|Opisthokonta	33154|Opisthokonta	DTZ	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_1,LRR_6
WLSH2_k127_1501148_0	91604.ID47_02320	0.0	1284.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,47F10@766|Rickettsiales	766|Rickettsiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WLSH2_k127_1501148_15	985867.AEWF01000006_gene565	1.426e-15	78.0	2AKVI@1|root,31BNQ@2|Bacteria,1Q7HY@1224|Proteobacteria,2VDP7@28211|Alphaproteobacteria,47GKW@766|Rickettsiales	766|Rickettsiales	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
WLSH2_k127_1501148_14	1298867.AUES01000111_gene1945	1.119e-16	80.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria,2UGT0@28211|Alphaproteobacteria,3K14N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1501148_11	985867.AEWF01000003_gene875	7.888e-34	138.0	COG5389@1|root,COG5389@2|Bacteria,1Q74D@1224|Proteobacteria,2VD8S@28211|Alphaproteobacteria,47FKE@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
WLSH2_k127_1501148_18	1246448.ANAZ01000002_gene3887	4.477e-08	57.0	COG4453@1|root,COG4453@2|Bacteria,2IT03@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
WLSH2_k127_1501148_1	985867.AEWF01000001_gene2030	1.406e-221	702.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,47F3T@766|Rickettsiales	766|Rickettsiales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
WLSH2_k127_1507486_0	985867.AEWF01000004_gene220	8.581e-193	607.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,47F2P@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_1507486_1	985867.AEWF01000004_gene221	5.491e-125	404.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria,47F0U@766|Rickettsiales	766|Rickettsiales	I	3-hydroxyacyl-CoA dehydrogenase	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782,ko:K07516	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
WLSH2_k127_1877122_5	985867.AEWF01000004_gene191	1.91e-98	363.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2U0US@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank_2,Ank_4,Ank_5,PRANC
WLSH2_k127_1877122_20	5872.XP_004833234.1	4.321e-05	58.0	COG4281@1|root,KOG0817@2759|Eukaryota,3YAR5@5794|Apicomplexa,3KCJE@422676|Aconoidasida,3Z624@5863|Piroplasmida	422676|Aconoidasida	I	Acyl CoA binding protein	-	GO:0002039,GO:0003674,GO:0005070,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006810,GO:0006839,GO:0006915,GO:0006996,GO:0007005,GO:0007006,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008219,GO:0009966,GO:0009967,GO:0009987,GO:0010638,GO:0010646,GO:0010647,GO:0010821,GO:0010822,GO:0010941,GO:0010942,GO:0012501,GO:0016043,GO:0023051,GO:0023052,GO:0023056,GO:0030054,GO:0030674,GO:0031974,GO:0031981,GO:0032879,GO:0032880,GO:0033043,GO:0035556,GO:0035591,GO:0042802,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045786,GO:0046902,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051059,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051716,GO:0051726,GO:0060090,GO:0060341,GO:0061024,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0071840,GO:0072331,GO:0072332,GO:0090559,GO:0097190,GO:0097193,GO:1900117,GO:1900119,GO:1900739,GO:1900740,GO:1901028,GO:1901030,GO:1901796,GO:1902531,GO:1903747,GO:1903749,GO:1903827,GO:1903829,GO:1904951,GO:1905475,GO:1905477,GO:2001233,GO:2001235	-	-	-	-	-	-	-	-	-	-	ACBP,Ank_2,Ank_4
WLSH2_k127_1877122_0	244582.JQAK01000001_gene2088	2.027e-256	803.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,47EV9@766|Rickettsiales	766|Rickettsiales	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_1877122_1	91604.ID47_00545	1.41e-192	616.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,47EWC@766|Rickettsiales	766|Rickettsiales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WLSH2_k127_1877122_6	244582.JQAK01000004_gene341	1.022e-77	263.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,47FDC@766|Rickettsiales	766|Rickettsiales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
WLSH2_k127_1877122_15	985867.AEWF01000001_gene1830	6.894e-27	117.0	COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,2UGR1@28211|Alphaproteobacteria,47GPN@766|Rickettsiales	766|Rickettsiales	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
WLSH2_k127_1877122_4	985867.AEWF01000006_gene566	1.191e-115	380.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,47FAH@766|Rickettsiales	766|Rickettsiales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WLSH2_k127_1877122_2	91604.ID47_01860	4.153e-172	545.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2TSD0@28211|Alphaproteobacteria,47FWI@766|Rickettsiales	766|Rickettsiales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WLSH2_k127_1877122_19	368408.Tpen_0945	8.183e-06	49.0	COG1881@1|root,arCOG04702@2157|Archaea,2XQN7@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
WLSH2_k127_1877122_13	244582.JQAK01000001_gene736	2.906e-36	139.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,47FNA@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WLSH2_k127_1877122_8	1469245.JFBG01000040_gene1725	2.578e-71	252.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,1RP15@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	GO:0003674,GO:0003824,GO:0003924,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
WLSH2_k127_1877122_16	91604.ID47_02550	3.906e-20	91.0	COG1396@1|root,COG1396@2|Bacteria,1NGFD@1224|Proteobacteria,2UJZF@28211|Alphaproteobacteria,47GHQ@766|Rickettsiales	766|Rickettsiales	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1877122_11	91604.ID47_02545	5.925e-60	224.0	COG3550@1|root,COG3550@2|Bacteria,1Q798@1224|Proteobacteria,2VDDU@28211|Alphaproteobacteria,47G2H@766|Rickettsiales	766|Rickettsiales	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
WLSH2_k127_1877122_17	305900.GV64_01110	5.891e-08	65.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,DUF349,Prophage_tail
WLSH2_k127_1877122_3	91604.ID47_03440	1.715e-144	461.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,47EXU@766|Rickettsiales	766|Rickettsiales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_1877122_14	91604.ID47_06625	1.146e-30	129.0	2AI4A@1|root,318IC@2|Bacteria,1Q0F8@1224|Proteobacteria,2V5TM@28211|Alphaproteobacteria,47G0U@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1877122_7	985867.AEWF01000004_gene301	6.965e-75	261.0	2C130@1|root,32R80@2|Bacteria,1RG16@1224|Proteobacteria,2U90P@28211|Alphaproteobacteria,47G3M@766|Rickettsiales	766|Rickettsiales	S	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
WLSH2_k127_1877122_10	985867.AEWF01000001_gene1731	3.261e-69	244.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,2TSNZ@28211|Alphaproteobacteria,47FPV@766|Rickettsiales	766|Rickettsiales	P	Ion transport protein	-	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
WLSH2_k127_1877122_18	5722.XP_001304415.1	5.8e-06	54.0	COG0666@1|root,KOG4177@2759|Eukaryota	5722.XP_001304415.1|-	I	spectrin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1877122_9	1122164.JHWF01000018_gene627	1.275e-70	245.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,1JD8H@118969|Legionellales	118969|Legionellales	F	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
WLSH2_k127_1877122_12	1288826.MSNKSG1_05873	4.097e-55	207.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1S48Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH2_k127_1890325_1	985867.AEWF01000003_gene872	2.986e-89	302.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2TR57@28211|Alphaproteobacteria,47F52@766|Rickettsiales	766|Rickettsiales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WLSH2_k127_1890325_0	91604.ID47_10665	5.658e-120	394.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,47F1P@766|Rickettsiales	766|Rickettsiales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WLSH2_k127_1890325_2	244582.JQAK01000001_gene1668	1.597e-61	218.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,47FCE@766|Rickettsiales	766|Rickettsiales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WLSH2_k127_1890574_1	1144888.CM001467_gene468	1.257e-128	424.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRQD@28211|Alphaproteobacteria,47F4F@766|Rickettsiales	766|Rickettsiales	EGP	COG0477 Permeases of the major facilitator superfamily	bcr2	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
WLSH2_k127_1890574_2	748247.AZKH_2559	1.947e-70	245.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,2KW94@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
WLSH2_k127_1890574_0	13689.BV96_04083	1.913e-167	553.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria,2K19E@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WLSH2_k127_1890574_3	1267005.KB911255_gene2387	1.206e-05	47.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_1890574_4	244582.JQAK01000001_gene1860	0.0008007	44.0	COG3293@1|root,COG3293@2|Bacteria,1Q8IA@1224|Proteobacteria,2UWD1@28211|Alphaproteobacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
WLSH2_k127_1919535_0	985867.AEWF01000003_gene715	4.651e-60	216.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,2V8RN@28211|Alphaproteobacteria,47F9D@766|Rickettsiales	766|Rickettsiales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_1919535_1	985867.AEWF01000003_gene754	2.691e-28	119.0	COG1051@1|root,COG1051@2|Bacteria,1Q7I3@1224|Proteobacteria,2VDPB@28211|Alphaproteobacteria,47GM0@766|Rickettsiales	766|Rickettsiales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_1919535_2	91604.ID47_10605	3.019e-13	70.0	COG0454@1|root,COG2320@1|root,COG0456@2|Bacteria,COG2320@2|Bacteria,1RH46@1224|Proteobacteria,2U2UV@28211|Alphaproteobacteria,47GT1@766|Rickettsiales	766|Rickettsiales	K	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
WLSH2_k127_2020611_4	91604.ID47_04305	8.18e-162	515.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,47ETX@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
WLSH2_k127_2020611_12	91604.ID47_04300	2.231e-30	124.0	COG2204@1|root,COG2204@2|Bacteria,1Q76E@1224|Proteobacteria,2UW7Q@28211|Alphaproteobacteria,47FTT@766|Rickettsiales	766|Rickettsiales	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
WLSH2_k127_2020611_0	244582.JQAK01000001_gene2053	1.22e-280	881.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,47ETC@766|Rickettsiales	766|Rickettsiales	T	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_2020611_1	244582.JQAK01000001_gene2054	1.028e-227	713.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,47EYI@766|Rickettsiales	766|Rickettsiales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH2_k127_2020611_7	244582.JQAK01000001_gene1759	1.47e-125	404.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,47EWA@766|Rickettsiales	766|Rickettsiales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
WLSH2_k127_2020611_5	985867.AEWF01000003_gene659	1.813e-160	512.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria,47EUD@766|Rickettsiales	766|Rickettsiales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
WLSH2_k127_2020611_13	598659.NAMH_1184	1.125e-11	66.0	2AY0S@1|root,31Q2B@2|Bacteria,1QMQY@1224|Proteobacteria,42SY0@68525|delta/epsilon subdivisions,2YPGA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Bacteriophage replication gene A protein (GPA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPA
WLSH2_k127_2020611_3	1034943.BN1094_03115	2.82e-192	610.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,1RNQI@1236|Gammaproteobacteria,1JCV5@118969|Legionellales	118969|Legionellales	GM	Belongs to the mannose-6-phosphate isomerase type 2 family	-	-	-	-	-	-	-	-	-	-	-	-	MannoseP_isomer,NTP_transferase
WLSH2_k127_2020611_9	205918.Psyr_0917	1.042e-94	317.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,1S0H9@1236|Gammaproteobacteria,1Z8RA@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	V	ABC-2 type transporter	wzm	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
WLSH2_k127_2020611_6	925775.XVE_1967	1.788e-149	484.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1X76T@135614|Xanthomonadales	135614|Xanthomonadales	GM	ABC transporter	wzt	-	3.6.3.38	ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
WLSH2_k127_2020611_8	61647.LG71_13030	1.131e-95	357.0	COG0515@1|root,COG2227@1|root,COG2959@1|root,COG0515@2|Bacteria,COG2227@2|Bacteria,COG2959@2|Bacteria,1Q23S@1224|Proteobacteria,1RNW0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	HKLT	Methyltransferase domain	wxcB	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	APH,Methyltransf_31
WLSH2_k127_2020611_2	859657.RPSI07_2508	5.43e-204	700.0	COG0438@1|root,COG1216@1|root,COG1579@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG1579@2|Bacteria,1QWI8@1224|Proteobacteria,2W4RD@28216|Betaproteobacteria,1K6W4@119060|Burkholderiaceae	28216|Betaproteobacteria	H	methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_21
WLSH2_k127_2020611_10	1123288.SOV_3c08900	1.814e-82	314.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wbpX	-	-	ko:K12993	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glycos_transf_1
WLSH2_k127_2193765_7	985867.AEWF01000003_gene836	3.482e-64	225.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,47FA7@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179,ko:K06125	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117,M00128	R05000,R05615,R05616,R07273	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WLSH2_k127_2193765_10	244582.JQAK01000001_gene1826	3.222e-44	168.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,2U94R@28211|Alphaproteobacteria,47FGR@766|Rickettsiales	766|Rickettsiales	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WLSH2_k127_2193765_5	244582.JQAK01000001_gene1825	4.637e-65	227.0	COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,2UG7E@28211|Alphaproteobacteria,47FJ6@766|Rickettsiales	766|Rickettsiales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH2_k127_2193765_6	1207063.P24_00435	1.962e-64	224.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,2JS6P@204441|Rhodospirillales	204441|Rhodospirillales	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH2_k127_2193765_11	1384056.N787_10935	7.654e-42	158.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,1S5YQ@1236|Gammaproteobacteria,1X6MZ@135614|Xanthomonadales	135614|Xanthomonadales	J	Protein chain release factor B	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
WLSH2_k127_2193765_8	244582.JQAK01000001_gene1203	2.202e-59	209.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,47FGG@766|Rickettsiales	766|Rickettsiales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
WLSH2_k127_2193765_9	985867.AEWF01000002_gene1465	2.418e-49	181.0	COG3133@1|root,COG3133@2|Bacteria,1N6VZ@1224|Proteobacteria,2UJG5@28211|Alphaproteobacteria,47FJU@766|Rickettsiales	766|Rickettsiales	M	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
WLSH2_k127_2193765_4	91604.ID47_00705	2.852e-89	315.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,47FC3@766|Rickettsiales	766|Rickettsiales	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WLSH2_k127_2193765_12	244582.JQAK01000001_gene2137	5.299e-29	119.0	COG0607@1|root,COG0607@2|Bacteria,1Q2JH@1224|Proteobacteria,2UHT3@28211|Alphaproteobacteria,47G9X@766|Rickettsiales	766|Rickettsiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_2193765_0	244582.JQAK01000001_gene1936	5.421e-202	634.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,47F4J@766|Rickettsiales	766|Rickettsiales	P	ABC transporter	potA	-	3.6.3.30	ko:K02010,ko:K11076	ko02010,map02010	M00190,M00300	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.2	-	-	ABC_tran,TOBE_2
WLSH2_k127_2193765_2	91604.ID47_09320	3.273e-135	437.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,47F4R@766|Rickettsiales	766|Rickettsiales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11075	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
WLSH2_k127_2193765_3	91604.ID47_09315	2.81e-125	405.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,47F8E@766|Rickettsiales	766|Rickettsiales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11074	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
WLSH2_k127_2193765_1	244582.JQAK01000001_gene1064	6.323e-138	449.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2TS6R@28211|Alphaproteobacteria,47EW7@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
WLSH2_k127_2237152_3	985867.AEWF01000004_gene197	4.933e-71	250.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,47FIF@766|Rickettsiales	766|Rickettsiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_2237152_4	91604.ID47_09895	4.521e-57	204.0	2C2J5@1|root,315UG@2|Bacteria,1RHAH@1224|Proteobacteria,2U94W@28211|Alphaproteobacteria,47FM2@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF3576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3576
WLSH2_k127_2237152_0	91604.ID47_09890	0.0	1297.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,47EWT@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH2_k127_2237152_6	91604.ID47_09885	5.432e-31	127.0	2BN63@1|root,32GTC@2|Bacteria,1Q7B0@1224|Proteobacteria,2VDFM@28211|Alphaproteobacteria,47G6T@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
WLSH2_k127_2237152_5	1034943.BN1094_02099	2.632e-46	170.0	2D8VC@1|root,32TS1@2|Bacteria,1MZWT@1224|Proteobacteria,1T748@1236|Gammaproteobacteria,1JEUU@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2237152_1	985867.AEWF01000002_gene1514	6.461e-95	321.0	COG4531@1|root,COG4531@2|Bacteria,1QTTI@1224|Proteobacteria,2TVXP@28211|Alphaproteobacteria,47FCA@766|Rickettsiales	766|Rickettsiales	P	cation ABC transporter, periplasmic cation-binding protein	znuA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
WLSH2_k127_2237152_2	91604.ID47_00645	1.741e-84	283.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2TQZM@28211|Alphaproteobacteria,47FDN@766|Rickettsiales	766|Rickettsiales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
WLSH2_k127_2239654_1	985867.AEWF01000002_gene1452	1.035e-122	400.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2TR10@28211|Alphaproteobacteria,47F4E@766|Rickettsiales	766|Rickettsiales	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WLSH2_k127_2239654_7	1449076.JOOE01000003_gene3695	6.092e-92	308.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2K0GH@204457|Sphingomonadales	204457|Sphingomonadales	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WLSH2_k127_2239654_8	91604.ID47_00315	1.092e-72	249.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,47FBC@766|Rickettsiales	766|Rickettsiales	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
WLSH2_k127_2239654_10	91604.ID47_00305	6.758e-21	93.0	2A1I2@1|root,30PRT@2|Bacteria,1Q6WT@1224|Proteobacteria,2VD01@28211|Alphaproteobacteria,47GEP@766|Rickettsiales	766|Rickettsiales	S	Hypoxia induced protein conserved region	-	-	-	-	-	-	-	-	-	-	-	-	HIG_1_N
WLSH2_k127_2239654_2	91604.ID47_04200	8.32e-114	371.0	COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,47F9E@766|Rickettsiales	766|Rickettsiales	O	Glutathione S-transferase	gst	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N_3
WLSH2_k127_2239654_5	985867.AEWF01000004_gene347	2.169e-102	340.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,47FBA@766|Rickettsiales	766|Rickettsiales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WLSH2_k127_2239654_12	373994.Riv7116_5077	1.368e-07	61.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc
WLSH2_k127_2239654_9	91604.ID47_09800	2.089e-47	179.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,47FGC@766|Rickettsiales	766|Rickettsiales	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
WLSH2_k127_2239654_3	985867.AEWF01000003_gene915	1.195e-107	353.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2TQP2@28211|Alphaproteobacteria,47F6K@766|Rickettsiales	766|Rickettsiales	J	COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH2_k127_2239654_6	985867.AEWF01000003_gene914	6.319e-96	319.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2TSU3@28211|Alphaproteobacteria,47F62@766|Rickettsiales	766|Rickettsiales	S	glutamine amidotransferases	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
WLSH2_k127_2239654_11	448385.sce1315	8.812e-21	105.0	COG0510@1|root,COG0510@2|Bacteria,1Q5YC@1224|Proteobacteria,43A99@68525|delta/epsilon subdivisions,2X93X@28221|Deltaproteobacteria,2Z1RX@29|Myxococcales	28221|Deltaproteobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_2239654_0	244582.JQAK01000001_gene1304	1.62e-301	940.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,47EZE@766|Rickettsiales	766|Rickettsiales	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
WLSH2_k127_2239654_4	1454004.AW11_01021	5.569e-103	361.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_9,dCache_1
WLSH2_k127_2272755_4	1144888.CM001467_gene914	6.984e-132	430.0	COG1373@1|root,COG1373@2|Bacteria,1NQGE@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
WLSH2_k127_2272755_8	985867.AEWF01000002_gene1523	1.795e-102	342.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,47FEB@766|Rickettsiales	766|Rickettsiales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WLSH2_k127_2272755_13	985867.AEWF01000001_gene2029	1.167e-58	207.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2U78W@28211|Alphaproteobacteria,47FF3@766|Rickettsiales	766|Rickettsiales	J	SpoU rRNA Methylase family	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WLSH2_k127_2272755_14	985867.AEWF01000001_gene2138	1.28e-19	102.0	2ADN0@1|root,313CS@2|Bacteria,1PS7A@1224|Proteobacteria,2V4ED@28211|Alphaproteobacteria,47FX4@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2272755_11	244582.JQAK01000004_gene262	1.275e-81	287.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Porin_2
WLSH2_k127_2272755_7	985867.AEWF01000001_gene1722	1.064e-103	346.0	COG0697@1|root,COG0697@2|Bacteria,1MVKG@1224|Proteobacteria,2TVQG@28211|Alphaproteobacteria,47FFA@766|Rickettsiales	766|Rickettsiales	EG	EamA-like transporter family	-	-	-	ko:K15268	-	-	-	-	ko00000,ko02000	2.A.7.3.2	-	-	EamA
WLSH2_k127_2272755_2	91604.ID47_10945	9.988e-155	497.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,47EU3@766|Rickettsiales	766|Rickettsiales	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WLSH2_k127_2272755_10	1267535.KB906767_gene2997	1.377e-85	289.0	COG4279@1|root,COG4279@2|Bacteria,3Y8KE@57723|Acidobacteria	57723|Acidobacteria	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
WLSH2_k127_2272755_0	1562701.BBOF01000030_gene889	1.735e-282	897.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2VIEC@28216|Betaproteobacteria,1K27X@119060|Burkholderiaceae	28216|Betaproteobacteria	L	helicase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF3670,Helicase_C,SNF2_N,SWIM
WLSH2_k127_2272755_12	1283300.ATXB01000001_gene1939	1.656e-78	272.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,1RN6A@1236|Gammaproteobacteria,1XE2V@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
WLSH2_k127_2272755_6	86106.I862_04625	1.921e-111	368.0	COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,2TRK2@28211|Alphaproteobacteria,47FB5@766|Rickettsiales	766|Rickettsiales	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
WLSH2_k127_2272755_9	985867.AEWF01000004_gene191	1.397e-92	339.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2U0US@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank_2,Ank_4,Ank_5,PRANC
WLSH2_k127_2272755_3	985867.AEWF01000001_gene1897	5.153e-151	490.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,2TRB1@28211|Alphaproteobacteria,47F0R@766|Rickettsiales	766|Rickettsiales	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
WLSH2_k127_2272755_1	91604.ID47_00675	2.613e-249	775.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2TV8B@28211|Alphaproteobacteria,47EXZ@766|Rickettsiales	766|Rickettsiales	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
WLSH2_k127_2272755_5	985867.AEWF01000004_gene297	3.481e-131	425.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,47F5A@766|Rickettsiales	766|Rickettsiales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WLSH2_k127_2273103_2	985867.AEWF01000002_gene1530	4.753e-88	301.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,47FAP@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH2_k127_2273103_1	985867.AEWF01000004_gene213	1.682e-112	369.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2TQXQ@28211|Alphaproteobacteria,47F8S@766|Rickettsiales	766|Rickettsiales	U	Biopolymer transport	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
WLSH2_k127_2273103_4	985867.AEWF01000004_gene212	9.327e-56	205.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,47FGI@766|Rickettsiales	766|Rickettsiales	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
WLSH2_k127_2273103_3	244582.JQAK01000001_gene1997	3.756e-72	255.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	tolA	-	4.2.1.1	ko:K01674,ko:K03646	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	TonB_2
WLSH2_k127_2273103_0	985867.AEWF01000004_gene209	7.403e-172	550.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,47F05@766|Rickettsiales	766|Rickettsiales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WLSH2_k127_2382976_2	91604.ID47_10310	2.846e-55	195.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,47FCR@766|Rickettsiales	766|Rickettsiales	C	Ferredoxin	fdxB	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
WLSH2_k127_2382976_1	985867.AEWF01000003_gene809	1.187e-77	270.0	COG5459@1|root,COG5459@2|Bacteria,1MWMM@1224|Proteobacteria,2TQX8@28211|Alphaproteobacteria,47FDP@766|Rickettsiales	766|Rickettsiales	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
WLSH2_k127_2382976_0	985867.AEWF01000002_gene1509	0.0	1357.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,47EVZ@766|Rickettsiales	766|Rickettsiales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WLSH2_k127_2382976_3	929713.NIASO_18295	9.763e-31	139.0	COG3621@1|root,COG3621@2|Bacteria,4NG71@976|Bacteroidetes,1IQQH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WLSH2_k127_2684554_1	91604.ID47_07990	6.008e-284	878.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,47FVM@766|Rickettsiales	766|Rickettsiales	I	Carboxyl transferase domain	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH2_k127_2684554_4	244582.JQAK01000001_gene1027	1.108e-59	216.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria,47GAA@766|Rickettsiales	766|Rickettsiales	E	Pyrroline-5-carboxylate reductase dimerisation	-	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
WLSH2_k127_2684554_3	985867.AEWF01000001_gene2012	6.694e-67	238.0	COG0741@1|root,COG0741@2|Bacteria,1RDXX@1224|Proteobacteria,2UCH1@28211|Alphaproteobacteria,47FHX@766|Rickettsiales	766|Rickettsiales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	mltE2	-	-	-	-	-	-	-	-	-	-	-	SLT
WLSH2_k127_2684554_2	91604.ID47_06065	1.192e-173	555.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,47FI7@766|Rickettsiales	766|Rickettsiales	E	3-phosphoshikimate 1-carboxyvinyltransferase	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
WLSH2_k127_2684554_5	86106.I862_02085	3.67e-13	81.0	COG4886@1|root,COG4886@2|Bacteria,1NJBW@1224|Proteobacteria,2UMRR@28211|Alphaproteobacteria,47GSJ@766|Rickettsiales	766|Rickettsiales	S	Leucine-rich repeats, outliers	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
WLSH2_k127_2684554_0	244582.JQAK01000001_gene1092	8.393e-306	958.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,47F2J@766|Rickettsiales	766|Rickettsiales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WLSH2_k127_2696290_1	985867.AEWF01000002_gene1490	5.405e-37	147.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
WLSH2_k127_2696290_0	985867.AEWF01000002_gene1489	1.563e-275	853.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,47F0F@766|Rickettsiales	766|Rickettsiales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WLSH2_k127_2696290_2	985867.AEWF01000002_gene1488	0.0008483	42.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,47F6G@766|Rickettsiales	766|Rickettsiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WLSH2_k127_2974300_8	1397284.AYMN01000008_gene2000	4.463e-07	52.0	COG3415@1|root,COG3415@2|Bacteria,1P1T3@1224|Proteobacteria,1SSIX@1236|Gammaproteobacteria,405EN@613|Serratia	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29
WLSH2_k127_2974300_4	244582.JQAK01000001_gene1710	3.125e-89	301.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U59A@28211|Alphaproteobacteria,47G7T@766|Rickettsiales	766|Rickettsiales	U	MarC family integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	MarC
WLSH2_k127_2974300_2	985867.AEWF01000003_gene750	5.408e-142	458.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,47G29@766|Rickettsiales	766|Rickettsiales	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WLSH2_k127_2974300_1	91604.ID47_11855	2.686e-174	553.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,47EZP@766|Rickettsiales	766|Rickettsiales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH2_k127_2974300_0	91604.ID47_11860	2.522e-188	595.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,47ETM@766|Rickettsiales	766|Rickettsiales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WLSH2_k127_2974300_6	91604.ID47_08930	3.978e-61	214.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,47FHB@766|Rickettsiales	766|Rickettsiales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
WLSH2_k127_2974300_5	244582.JQAK01000001_gene1966	2.868e-74	259.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,47F8J@766|Rickettsiales	766|Rickettsiales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
WLSH2_k127_2974300_7	91604.ID47_09575	1.339e-53	211.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,2U1Y2@28211|Alphaproteobacteria,47FMG@766|Rickettsiales	766|Rickettsiales	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
WLSH2_k127_2974300_3	91604.ID47_09570	1.5e-97	335.0	COG3898@1|root,COG3898@2|Bacteria,1P5RR@1224|Proteobacteria,2TT5Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	HemY domain protein	lapB	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_19
WLSH2_k127_2995694_36	1174504.AJTN02000153_gene986	8.829e-09	64.0	COG0454@1|root,COG0456@2|Bacteria,1VFVQ@1239|Firmicutes,4HK5T@91061|Bacilli,1ZIKN@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	ydhI	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
WLSH2_k127_2995694_14	1528098.NOVO_06585	3.64e-58	207.0	COG1670@1|root,COG1670@2|Bacteria,1R4VC@1224|Proteobacteria,2VGBK@28211|Alphaproteobacteria,47G7H@766|Rickettsiales	766|Rickettsiales	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_8
WLSH2_k127_2995694_13	86106.I862_03315	1.167e-68	241.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,2U4TZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CO	phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
WLSH2_k127_2995694_8	391896.A1I_05385	1.414e-110	368.0	COG1247@1|root,COG5628@1|root,COG1247@2|Bacteria,COG5628@2|Bacteria,1NHRZ@1224|Proteobacteria,2TY5E@28211|Alphaproteobacteria,47GJE@766|Rickettsiales	766|Rickettsiales	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_2995694_25	1437425.CSEC_0377	3.084e-25	117.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	ko:K04791	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	Acyl_transf_1,HNH_4,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,PP-binding,ketoacyl-synt
WLSH2_k127_2995694_9	658187.LDG_7080	5.26e-94	319.0	COG3570@1|root,COG3570@2|Bacteria,1PMVT@1224|Proteobacteria,1TAIC@1236|Gammaproteobacteria,1JEVF@118969|Legionellales	118969|Legionellales	V	Aminoglycoside/hydroxyurea antibiotic resistance kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH_6_hur
WLSH2_k127_2995694_34	985867.AEWF01000009_gene1125	1.468e-11	72.0	28SB2@1|root,2ZEN3@2|Bacteria,1P6SB@1224|Proteobacteria,2UX6J@28211|Alphaproteobacteria,47GI7@766|Rickettsiales	766|Rickettsiales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
WLSH2_k127_2995694_30	244581.IM40_07830	1.699e-16	81.0	COG3311@1|root,COG3311@2|Bacteria,1N9IM@1224|Proteobacteria,2UH9G@28211|Alphaproteobacteria,47FV4@766|Rickettsiales	766|Rickettsiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2995694_23	420246.GTNG_2852	5.764e-26	123.0	COG3935@1|root,COG3935@2|Bacteria,1W6YH@1239|Firmicutes,4I46Y@91061|Bacilli,1WHNM@129337|Geobacillus	91061|Bacilli	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
WLSH2_k127_2995694_31	244581.IM40_09915	1.626e-15	83.0	2EI4V@1|root,33BW7@2|Bacteria	2|Bacteria	S	Protein of unknwon function (DUF3310)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3310
WLSH2_k127_2995694_27	985867.AEWF01000009_gene1127	2.09e-22	100.0	2DHT4@1|root,300U8@2|Bacteria,1PRHT@1224|Proteobacteria,2VDDV@28211|Alphaproteobacteria,47GJP@766|Rickettsiales	766|Rickettsiales	S	TraL protein	-	-	-	ko:K12068	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraL
WLSH2_k127_2995694_15	985867.AEWF01000009_gene1128	4.996e-57	204.0	2DBUJ@1|root,2ZB5X@2|Bacteria,1P88B@1224|Proteobacteria,2UKV0@28211|Alphaproteobacteria,47FXJ@766|Rickettsiales	766|Rickettsiales	S	TraE protein	-	-	-	ko:K12067	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraE
WLSH2_k127_2995694_19	985867.AEWF01000009_gene1129	6.336e-40	157.0	2ENFR@1|root,33G34@2|Bacteria,1NMEW@1224|Proteobacteria,2UVZT@28211|Alphaproteobacteria,47GEY@766|Rickettsiales	766|Rickettsiales	S	TraK protein	-	-	-	-	-	-	-	-	-	-	-	-	TraK
WLSH2_k127_2995694_10	985867.AEWF01000009_gene1130	3.685e-91	316.0	COG2433@1|root,COG2433@2|Bacteria,1QUPW@1224|Proteobacteria,2TY5C@28211|Alphaproteobacteria,47FER@766|Rickettsiales	1224|Proteobacteria	S	Bacterial conjugation TrbI-like protein	traB	-	-	ko:K12065	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TrbI
WLSH2_k127_2995694_1	985867.AEWF01000009_gene1132	1.856e-218	705.0	COG3451@1|root,COG3451@2|Bacteria,1MUEN@1224|Proteobacteria,2TRBA@28211|Alphaproteobacteria,47F7C@766|Rickettsiales	766|Rickettsiales	U	F pilus assembly Type-IV secretion system for plasmid transfer	-	-	-	ko:K12063	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	AAA_10,TraC_F_IV
WLSH2_k127_2995694_21	985867.AEWF01000009_gene1135	4.077e-32	132.0	COG4959@1|root,COG4959@2|Bacteria,1NPCA@1224|Proteobacteria,2UN0F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OU	Signal peptidase, peptidase S26	-	-	-	ko:K12062	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	Peptidase_S26
WLSH2_k127_2995694_17	985867.AEWF01000009_gene1136	3.97e-46	173.0	2CGUX@1|root,31QWG@2|Bacteria,1N1MK@1224|Proteobacteria,2UCMG@28211|Alphaproteobacteria,47FGF@766|Rickettsiales	766|Rickettsiales	S	Conjugal transfer protein TraW	-	-	-	ko:K12061	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	-
WLSH2_k127_2995694_4	985867.AEWF01000009_gene1138	1.977e-159	507.0	28HGF@1|root,2Z7SA@2|Bacteria,1MXUA@1224|Proteobacteria,2U2HG@28211|Alphaproteobacteria,47EWU@766|Rickettsiales	766|Rickettsiales	S	TraU protein	traU	-	-	ko:K12060	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraU
WLSH2_k127_2995694_28	91604.ID47_01350	1.718e-21	101.0	2CIAZ@1|root,2Z7YC@2|Bacteria,1NGH1@1224|Proteobacteria,2UK7J@28211|Alphaproteobacteria,47FR1@766|Rickettsiales	766|Rickettsiales	S	Type-F conjugative transfer system pilin assembly protein	-	-	-	ko:K12059	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TrbC_Ftype
WLSH2_k127_2995694_5	985867.AEWF01000009_gene1140	9.275e-137	452.0	28KC1@1|root,2Z9Z1@2|Bacteria,1MW96@1224|Proteobacteria,2U6RW@28211|Alphaproteobacteria,47FBP@766|Rickettsiales	766|Rickettsiales	S	Type-1V conjugative transfer system mating pair stabilisation	-	-	-	ko:K12058	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraN
WLSH2_k127_2995694_11	985867.AEWF01000009_gene1141	4.651e-87	295.0	COG0526@1|root,COG0526@2|Bacteria,1MXG2@1224|Proteobacteria,2U468@28211|Alphaproteobacteria,47F99@766|Rickettsiales	766|Rickettsiales	CO	F plasmid transfer operon protein	-	-	-	ko:K12057	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraF
WLSH2_k127_2995694_3	91604.ID47_01325	1.312e-188	601.0	28MTB@1|root,2ZB1J@2|Bacteria,1MWD0@1224|Proteobacteria,2UGCF@28211|Alphaproteobacteria,47GRW@766|Rickettsiales	766|Rickettsiales	S	Conjugative relaxosome accessory transposon protein	-	-	-	ko:K12072	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraH
WLSH2_k127_2995694_0	91604.ID47_01320	3.721e-289	914.0	COG4678@1|root,COG4678@2|Bacteria,1MXCR@1224|Proteobacteria,2U372@28211|Alphaproteobacteria,47GSX@766|Rickettsiales	766|Rickettsiales	G	TraG-like protein, N-terminal region	-	-	-	ko:K12056	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	TraG_N
WLSH2_k127_2995694_2	985867.AEWF01000012_gene1315	1.067e-197	632.0	COG3505@1|root,COG3505@2|Bacteria,1PWIG@1224|Proteobacteria,2TSDY@28211|Alphaproteobacteria,47EWB@766|Rickettsiales	766|Rickettsiales	U	Type IV secretory system Conjugative DNA transfer	-	-	-	-	-	-	-	-	-	-	-	-	TrwB_AAD_bind
WLSH2_k127_2995694_22	1122164.JHWF01000023_gene426	5.922e-27	122.0	COG0500@1|root,COG2226@2|Bacteria,1N6BW@1224|Proteobacteria,1SXHD@1236|Gammaproteobacteria,1JCCA@118969|Legionellales	118969|Legionellales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12
WLSH2_k127_2995694_20	1121033.AUCF01000013_gene1615	1.249e-35	140.0	COG1522@1|root,COG1522@2|Bacteria,1N0DP@1224|Proteobacteria,2UC1F@28211|Alphaproteobacteria,2JTAZ@204441|Rhodospirillales	204441|Rhodospirillales	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_AsnC-type
WLSH2_k127_2995694_24	1121033.AUCF01000028_gene355	1.414e-25	113.0	COG1280@1|root,COG1280@2|Bacteria,1N227@1224|Proteobacteria,2UCZW@28211|Alphaproteobacteria,2JS9J@204441|Rhodospirillales	204441|Rhodospirillales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
WLSH2_k127_2995694_6	765952.PUV_15050	1.14e-133	434.0	COG2334@1|root,COG2334@2|Bacteria,2JFUX@204428|Chlamydiae	204428|Chlamydiae	S	Choline/ethanolamine kinase	-	-	-	ko:K18844	-	-	-	-	ko00000,ko01504	-	-	-	APH
WLSH2_k127_2995694_12	985867.AEWF01000002_gene1418	1.073e-70	244.0	COG1051@1|root,COG1051@2|Bacteria,1Q922@1224|Proteobacteria,2URFC@28211|Alphaproteobacteria,47F9R@766|Rickettsiales	766|Rickettsiales	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_2995694_18	86106.I862_01755	5.612e-43	161.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,NUDIX
WLSH2_k127_2995694_37	765952.PUV_15780	1.204e-08	63.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WLSH2_k127_2995694_7	406124.ACPC01000009_gene1442	1.525e-114	378.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,4HB1P@91061|Bacilli,1ZQ9Y@1386|Bacillus	91061|Bacilli	V	peptidase S66	yocD	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
WLSH2_k127_2995694_26	658187.LDG_7088	1.99e-22	103.0	COG3153@1|root,COG3153@2|Bacteria,1MYMQ@1224|Proteobacteria,1SA16@1236|Gammaproteobacteria,1JEJ6@118969|Legionellales	118969|Legionellales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_2995694_16	658187.LDG_7093	1.032e-53	198.0	COG0500@1|root,COG2226@2|Bacteria,1R5JA@1224|Proteobacteria,1T4YK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH2_k127_2995694_33	1528098.NOVO_00860	5.402e-12	77.0	COG3903@1|root,COG3903@2|Bacteria,1Q7EE@1224|Proteobacteria,2VDJE@28211|Alphaproteobacteria,47GDG@766|Rickettsiales	766|Rickettsiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_8
WLSH2_k127_30055_10	5911.EAS06522	0.0009521	49.0	COG0484@1|root,KOG0712@2759|Eukaryota,3ZD6P@5878|Ciliophora	5878|Ciliophora	O	DnaJ central domain	-	-	-	ko:K09503	ko04141,map04141	-	-	-	ko00000,ko00001,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH2_k127_30055_7	336407.RBE_0908	1.283e-57	206.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2TR4Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the WrbA family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WLSH2_k127_30055_3	244582.JQAK01000001_gene1611	1.011e-111	367.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,47F1S@766|Rickettsiales	766|Rickettsiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
WLSH2_k127_30055_5	985867.AEWF01000003_gene854	1.055e-78	271.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,2U933@28211|Alphaproteobacteria,47G37@766|Rickettsiales	766|Rickettsiales	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
WLSH2_k127_30055_6	91604.ID47_10585	2.744e-63	222.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,47FEH@766|Rickettsiales	766|Rickettsiales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH2_k127_30055_0	985867.AEWF01000003_gene856	0.0	1430.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,47EW0@766|Rickettsiales	766|Rickettsiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH2_k127_30055_2	244582.JQAK01000001_gene1913	4.823e-177	581.0	COG1138@1|root,COG3088@1|root,COG1138@2|Bacteria,COG3088@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,47EYR@766|Rickettsiales	766|Rickettsiales	O	Cytochrome c-type biogenesis protein ccmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WLSH2_k127_30055_1	244582.JQAK01000001_gene769	3.677e-260	817.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,47EWH@766|Rickettsiales	766|Rickettsiales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WLSH2_k127_30055_9	1172181.KB911708_gene8083	1.164e-09	71.0	COG1404@1|root,COG1404@2|Bacteria,2GIRE@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	mycP	-	-	ko:K14743	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
WLSH2_k127_30055_4	91604.ID47_00205	3.36e-93	312.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,47F7G@766|Rickettsiales	766|Rickettsiales	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
WLSH2_k127_3018623_7	91604.ID47_02440	1.333e-06	49.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2TR5A@28211|Alphaproteobacteria,47F55@766|Rickettsiales	766|Rickettsiales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
WLSH2_k127_3018623_6	244582.JQAK01000001_gene1731	3.573e-28	121.0	COG1076@1|root,COG1076@2|Bacteria	2|Bacteria	O	ATPase activator activity	hscB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234	-	ko:K04082,ko:K05801	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C,TerB
WLSH2_k127_3018623_5	1380391.JIAS01000013_gene3547	1.258e-46	170.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria,2JSZV@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
WLSH2_k127_3018623_3	985867.AEWF01000003_gene804	1.094e-67	231.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2TU34@28211|Alphaproteobacteria,47F8P@766|Rickettsiales	766|Rickettsiales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WLSH2_k127_3018623_0	244582.JQAK01000001_gene1734	5.706e-204	642.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,47EYU@766|Rickettsiales	766|Rickettsiales	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WLSH2_k127_3018623_1	244582.JQAK01000001_gene1735	3.1e-136	443.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,47F0P@766|Rickettsiales	766|Rickettsiales	E	COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	spl1	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WLSH2_k127_3018623_4	244582.JQAK01000001_gene1736	6.544e-51	187.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2U5B9@28211|Alphaproteobacteria,47FFG@766|Rickettsiales	766|Rickettsiales	K	Transcriptional regulator	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
WLSH2_k127_3018623_2	985867.AEWF01000003_gene800	8.891e-117	379.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria,47F70@766|Rickettsiales	766|Rickettsiales	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
WLSH2_k127_3125491_0	244582.JQAK01000001_gene800	1.024e-74	260.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,47F1C@766|Rickettsiales	766|Rickettsiales	M	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_3125491_1	985867.AEWF01000001_gene2280	1.126e-57	220.0	2A23R@1|root,30QDZ@2|Bacteria,1Q78T@1224|Proteobacteria,2VDDG@28211|Alphaproteobacteria,47G19@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3186500_4	1122164.JHWF01000038_gene654	1.235e-12	81.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1JCUJ@118969|Legionellales	118969|Legionellales	S	Sel1-like repeats.	-	-	-	ko:K15475	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	Sel1
WLSH2_k127_3186500_0	985867.AEWF01000002_gene1433	0.0	1360.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,47ETH@766|Rickettsiales	766|Rickettsiales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WLSH2_k127_3186500_2	985867.AEWF01000001_gene2028	3.365e-158	504.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,47F02@766|Rickettsiales	766|Rickettsiales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
WLSH2_k127_3186500_1	91604.ID47_08730	1.229e-213	671.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,47EV2@766|Rickettsiales	766|Rickettsiales	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
WLSH2_k127_3186500_3	985867.AEWF01000004_gene191	1.509e-27	121.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2U0US@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ankyrin repeat	-	-	-	ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank_2,Ank_4,Ank_5,PRANC
WLSH2_k127_3189011_0	244581.IM40_08080	2.095e-183	586.0	COG1672@1|root,COG1672@2|Bacteria,1MWJX@1224|Proteobacteria,2V4HQ@28211|Alphaproteobacteria,47FYU@766|Rickettsiales	766|Rickettsiales	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
WLSH2_k127_3189011_1	244582.JQAK01000001_gene1082	1.947e-19	88.0	COG2011@1|root,COG2011@2|Bacteria,1MW8E@1224|Proteobacteria,2TU01@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type metal ion transport system permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
WLSH2_k127_3197872_2	91604.ID47_06285	3.29e-197	621.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,47EY1@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WLSH2_k127_3197872_3	91604.ID47_00010	5.561e-147	475.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,47F39@766|Rickettsiales	766|Rickettsiales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WLSH2_k127_3197872_1	985867.AEWF01000004_gene230	3.006e-225	707.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,47EXY@766|Rickettsiales	766|Rickettsiales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WLSH2_k127_3197872_4	985867.AEWF01000003_gene810	8.2e-48	179.0	2AE0H@1|root,313T4@2|Bacteria,1PSYX@1224|Proteobacteria,2V4Z0@28211|Alphaproteobacteria,47G0Y@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3197872_5	43989.cce_2547	1.299e-24	112.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,3KHPQ@43988|Cyanothece	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH2_k127_3197872_0	1174528.JH992893_gene5702	9.02e-277	898.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
WLSH2_k127_3230002_15	1035839.AFNK01000001_gene363	0.0007787	50.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,1Y7E4@135625|Pasteurellales	135625|Pasteurellales	M	OmpA-like transmembrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,OmpA_membrane
WLSH2_k127_3230002_9	334545.CCMG01000016_gene1286	3.086e-35	137.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM Excinuclease ABC, C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH2_k127_3230002_0	985867.AEWF01000003_gene664	4.271e-241	754.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2TUN4@28211|Alphaproteobacteria,47G0Q@766|Rickettsiales	766|Rickettsiales	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
WLSH2_k127_3230002_1	985867.AEWF01000001_gene1901	7.869e-165	537.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,47F85@766|Rickettsiales	766|Rickettsiales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
WLSH2_k127_3230002_7	91604.ID47_06125	6.199e-59	207.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2U7D8@28211|Alphaproteobacteria,47FPD@766|Rickettsiales	766|Rickettsiales	I	COG2867 oligoketide cyclase lipid transport protein	ratA	-	-	ko:K18588	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
WLSH2_k127_3230002_8	91604.ID47_08780	8.015e-46	170.0	COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,47FGP@766|Rickettsiales	766|Rickettsiales	K	ROS/MUCR transcriptional regulator protein	-	-	-	-	-	-	-	-	-	-	-	-	ROS_MUCR
WLSH2_k127_3230002_14	756067.MicvaDRAFT_1375	7.919e-16	85.0	COG0454@1|root,COG0456@2|Bacteria,1G5TG@1117|Cyanobacteria,1HB8N@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
WLSH2_k127_3230002_6	985867.AEWF01000002_gene1549	1.439e-67	232.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,47FD9@766|Rickettsiales	766|Rickettsiales	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WLSH2_k127_3230002_3	91604.ID47_08865	2.53e-124	404.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,47F5V@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WLSH2_k127_3230002_2	985867.AEWF01000002_gene1547	5.592e-161	528.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,47EZR@766|Rickettsiales	766|Rickettsiales	M	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_8
WLSH2_k127_3230002_11	91604.ID47_07015	4.785e-26	111.0	COG2944@1|root,COG2944@2|Bacteria,1NH2C@1224|Proteobacteria,2UK4P@28211|Alphaproteobacteria,47GS3@766|Rickettsiales	766|Rickettsiales	K	Helix-turn-helix	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
WLSH2_k127_3230002_12	985867.AEWF01000008_gene1037	7.999e-26	110.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,2UGH7@28211|Alphaproteobacteria,47GBY@766|Rickettsiales	766|Rickettsiales	S	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3230002_13	27923.ML12827a-PA	1.48e-25	119.0	COG4886@1|root,KOG0619@2759|Eukaryota,38C70@33154|Opisthokonta,3BCK5@33208|Metazoa	33208|Metazoa	S	Leucine-rich repeat protein	SHOC2	GO:0000164,GO:0002119,GO:0002164,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007264,GO:0007265,GO:0007275,GO:0007517,GO:0008150,GO:0008157,GO:0008287,GO:0008543,GO:0009719,GO:0009791,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010646,GO:0010647,GO:0010921,GO:0016020,GO:0017016,GO:0019208,GO:0019220,GO:0019222,GO:0019888,GO:0019899,GO:0019902,GO:0019903,GO:0023051,GO:0023052,GO:0023056,GO:0030234,GO:0031267,GO:0031323,GO:0031344,GO:0031399,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032991,GO:0035303,GO:0035304,GO:0035556,GO:0040025,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043666,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046578,GO:0046579,GO:0048513,GO:0048518,GO:0048522,GO:0048569,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051020,GO:0051056,GO:0051057,GO:0051128,GO:0051171,GO:0051174,GO:0051246,GO:0051336,GO:0051716,GO:0060255,GO:0061061,GO:0065007,GO:0065009,GO:0070013,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071774,GO:0071944,GO:0080090,GO:0098772,GO:1902494,GO:1902531,GO:1902533,GO:1903293	-	ko:K19613	ko04014,map04014	-	-	-	ko00000,ko00001	-	-	-	LRR_1,LRR_8
WLSH2_k127_3230002_10	7739.XP_002595932.1	3.52e-27	125.0	COG4886@1|root,KOG0619@2759|Eukaryota	2759|Eukaryota	U	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8
WLSH2_k127_3230002_4	244582.JQAK01000001_gene838	3.376e-123	406.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2TT3J@28211|Alphaproteobacteria,47FF1@766|Rickettsiales	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
WLSH2_k127_3230002_5	985867.AEWF01000002_gene1349	1.023e-80	277.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,47EWP@766|Rickettsiales	766|Rickettsiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH2_k127_3239306_6	91604.ID47_10605	1.373e-13	71.0	COG0454@1|root,COG2320@1|root,COG0456@2|Bacteria,COG2320@2|Bacteria,1RH46@1224|Proteobacteria,2U2UV@28211|Alphaproteobacteria,47GT1@766|Rickettsiales	766|Rickettsiales	K	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
WLSH2_k127_3239306_1	570417.WP1305	2.145e-149	479.0	COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,2TV70@28211|Alphaproteobacteria,47F3I@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
WLSH2_k127_3239306_4	658187.LDG_7101	2.757e-47	173.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Cupin_2
WLSH2_k127_3239306_0	452471.Aasi_1260	6.098e-197	629.0	COG1132@1|root,COG1132@2|Bacteria,4NZYU@976|Bacteroidetes,47XHN@768503|Cytophagia	976|Bacteroidetes	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_3239306_8	745411.B3C1_05150	0.0002382	50.0	COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1J672@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_00643	ARD
WLSH2_k127_3239306_7	390989.JOEG01000009_gene946	3.504e-08	59.0	COG3896@1|root,COG3896@2|Bacteria,2IFF0@201174|Actinobacteria,4DE7I@85008|Micromonosporales	201174|Actinobacteria	V	Chloramphenicol phosphotransferase-like protein	cpt	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
WLSH2_k127_3239306_3	658187.LDG_7085	1.231e-48	177.0	COG3896@1|root,COG3896@2|Bacteria,1NEN0@1224|Proteobacteria,1STA5@1236|Gammaproteobacteria,1JFD8@118969|Legionellales	118969|Legionellales	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
WLSH2_k127_3239306_5	306281.AJLK01000114_gene4306	4.6e-19	93.0	COG0454@1|root,COG0456@2|Bacteria,1GR2Z@1117|Cyanobacteria	1117|Cyanobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_3239306_2	1268635.Loa_02063	8.599e-88	306.0	COG3173@1|root,COG3173@2|Bacteria,1PN9I@1224|Proteobacteria,1RVJZ@1236|Gammaproteobacteria,1JFMX@118969|Legionellales	118969|Legionellales	K	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_329047_2	985867.AEWF01000006_gene583	9.21e-53	193.0	COG0454@1|root,COG2320@1|root,COG0456@2|Bacteria,COG2320@2|Bacteria,1RD0I@1224|Proteobacteria,2UIWW@28211|Alphaproteobacteria,47FC9@766|Rickettsiales	766|Rickettsiales	K	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,GrpB
WLSH2_k127_329047_3	711393.AYRX01000079_gene5273	1.65e-49	183.0	COG0259@1|root,COG0259@2|Bacteria,2IFQZ@201174|Actinobacteria	201174|Actinobacteria	H	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region	-	-	1.10.3.16	ko:K20262	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	R11490,R11491,R11492	RC03450,RC03451	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
WLSH2_k127_329047_1	1399147.P618_200431	1.08e-61	216.0	COG0454@1|root,COG0456@2|Bacteria,1NCA0@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
WLSH2_k127_329047_0	86106.I862_06950	8.434e-89	303.0	COG3173@1|root,COG3173@2|Bacteria,1MYZZ@1224|Proteobacteria,2V9VW@28211|Alphaproteobacteria,47G65@766|Rickettsiales	766|Rickettsiales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_329047_4	1304866.K413DRAFT_0395	4.175e-34	133.0	COG3911@1|root,COG3911@2|Bacteria,1USSP@1239|Firmicutes,24ZQP@186801|Clostridia,36R5U@31979|Clostridiaceae	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
WLSH2_k127_3313823_22	643562.Daes_3209	2.101e-24	109.0	29XY6@1|root,30JQT@2|Bacteria,1PWGF@1224|Proteobacteria,4373T@68525|delta/epsilon subdivisions,2X1XZ@28221|Deltaproteobacteria,2MFU4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Lipid A 3-O-deacylase (PagL)	-	-	-	ko:K12976	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	PagL
WLSH2_k127_3313823_29	500637.PROVRUST_05485	0.0001347	52.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3Z8RK@586|Providencia	1236|Gammaproteobacteria	M	Belongs to the ompA family	ompA	GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022	OMP_b-brl,OmpA,OmpA_membrane
WLSH2_k127_3313823_2	985867.AEWF01000004_gene68	6.399e-256	801.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,47F0M@766|Rickettsiales	766|Rickettsiales	S	ABC transporter C-terminal domain	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
WLSH2_k127_3313823_27	438753.AZC_3575	2.226e-10	73.0	COG5410@1|root,COG5410@2|Bacteria,1N0W2@1224|Proteobacteria,2U18J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
WLSH2_k127_3313823_4	765952.PUV_16110	1.574e-168	544.0	COG1672@1|root,COG1672@2|Bacteria,2JGKE@204428|Chlamydiae	204428|Chlamydiae	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,HTH_5
WLSH2_k127_3313823_5	985867.AEWF01000004_gene333	1.57e-164	522.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2TS2N@28211|Alphaproteobacteria,47EVV@766|Rickettsiales	766|Rickettsiales	J	glycyl-tRNA synthetase, alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
WLSH2_k127_3313823_3	91604.ID47_04275	3.043e-249	786.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2TQKJ@28211|Alphaproteobacteria,47F1H@766|Rickettsiales	766|Rickettsiales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
WLSH2_k127_3313823_7	331113.SNE_A04860	7.509e-128	420.0	COG0477@1|root,COG2814@2|Bacteria,2JGF2@204428|Chlamydiae	204428|Chlamydiae	EGP	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
WLSH2_k127_3313823_6	331113.SNE_A04860	1.265e-133	437.0	COG0477@1|root,COG2814@2|Bacteria,2JGF2@204428|Chlamydiae	204428|Chlamydiae	EGP	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
WLSH2_k127_3313823_15	244582.JQAK01000001_gene1756	9.308e-59	207.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
WLSH2_k127_3313823_8	985867.AEWF01000004_gene98	2.848e-127	411.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,47FW8@766|Rickettsiales	766|Rickettsiales	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH2_k127_3313823_16	237368.SCABRO_02688	8.403e-52	190.0	COG3646@1|root,COG3646@2|Bacteria,2J4TE@203682|Planctomycetes	203682|Planctomycetes	S	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
WLSH2_k127_3313823_25	91604.ID47_02060	4.112e-15	77.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2VDAN@28211|Alphaproteobacteria,47FTE@766|Rickettsiales	766|Rickettsiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WLSH2_k127_3313823_24	91604.ID47_02065	1.943e-19	91.0	COG1826@1|root,COG1826@2|Bacteria,1Q7J1@1224|Proteobacteria,2VDQA@28211|Alphaproteobacteria,47GP0@766|Rickettsiales	766|Rickettsiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	-
WLSH2_k127_3313823_11	985867.AEWF01000001_gene2039	6.018e-97	323.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,47FAE@766|Rickettsiales	766|Rickettsiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WLSH2_k127_3313823_1	244582.JQAK01000001_gene942	9.02e-272	854.0	COG4953@1|root,COG4953@2|Bacteria,1QVVU@1224|Proteobacteria,2TWK8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Penicillin-Binding Protein C-terminus Family	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
WLSH2_k127_3313823_14	1449063.JMLS01000024_gene3668	5.519e-75	257.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1VA03@1239|Firmicutes,4HBU4@91061|Bacilli,26U48@186822|Paenibacillaceae	91061|Bacilli	FL	Metal binding domain of Ada	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
WLSH2_k127_3313823_19	1408445.JHXP01000029_gene1814	1.114e-36	144.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,1SCEH@1236|Gammaproteobacteria,1JEMP@118969|Legionellales	118969|Legionellales	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
WLSH2_k127_3313823_17	1268072.PSAB_23745	1.096e-49	179.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli,26XT9@186822|Paenibacillaceae	91061|Bacilli	P	Alkylphosphonate utilization protein	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
WLSH2_k127_3313823_10	222534.KB893717_gene2138	2.775e-112	377.0	COG2865@1|root,COG2865@2|Bacteria,2GZ30@201174|Actinobacteria,4ETCG@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
WLSH2_k127_3313823_21	105420.BBPO01000059_gene3248	8.606e-27	115.0	COG1846@1|root,COG1846@2|Bacteria,2IIAV@201174|Actinobacteria,2NMB4@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR_2
WLSH2_k127_3313823_26	1121870.AUAA01000009_gene295	1.523e-11	70.0	COG5562@1|root,COG5562@2|Bacteria,4NR3A@976|Bacteroidetes,1I3BI@117743|Flavobacteriia,3HI90@358033|Chryseobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF1398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1398
WLSH2_k127_3313823_13	522772.Dacet_1720	2.022e-92	307.0	COG2818@1|root,COG2818@2|Bacteria	2|Bacteria	L	DNA-3-methyladenine glycosylase activity	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
WLSH2_k127_3313823_23	1041826.FCOL_08280	3.372e-24	115.0	COG4886@1|root,COG4886@2|Bacteria,4NPNU@976|Bacteroidetes,1I2Q2@117743|Flavobacteriia	976|Bacteroidetes	KLT	PFAM Leucine Rich Repeat	-	-	-	ko:K19613	ko04014,map04014	-	-	-	ko00000,ko00001	-	-	-	LRR_8
WLSH2_k127_3313823_0	244582.JQAK01000001_gene1718	0.0	1525.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1QVTW@1224|Proteobacteria,2TWJK@28211|Alphaproteobacteria,47EUW@766|Rickettsiales	766|Rickettsiales	CEH	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltD	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
WLSH2_k127_3313823_18	91604.ID47_04565	1.337e-46	171.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,47FGK@766|Rickettsiales	766|Rickettsiales	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxC2	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
WLSH2_k127_3313823_20	420324.KI912026_gene4975	4.19e-28	115.0	COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,1JVWQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Belongs to the BolA IbaG family	bolA2	-	-	-	-	-	-	-	-	-	-	-	BolA
WLSH2_k127_3313823_12	985867.AEWF01000004_gene262	1.593e-93	318.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria,47FF5@766|Rickettsiales	766|Rickettsiales	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WLSH2_k127_3313823_9	91604.ID47_04020	8.708e-117	384.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2U8WM@28211|Alphaproteobacteria,47F96@766|Rickettsiales	766|Rickettsiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_3439890_15	985867.AEWF01000007_gene377	1.351e-14	79.0	2AIWX@1|root,319EJ@2|Bacteria,1Q2HW@1224|Proteobacteria,2V66X@28211|Alphaproteobacteria,47G8E@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3439890_2	1173028.ANKO01000058_gene3036	4.478e-152	501.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_7,PAS_8,PAS_9,Response_reg
WLSH2_k127_3439890_8	244582.JQAK01000001_gene1938	2.958e-88	301.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,47F59@766|Rickettsiales	766|Rickettsiales	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WLSH2_k127_3439890_1	91604.ID47_00095	5.964e-173	554.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,47FA5@766|Rickettsiales	766|Rickettsiales	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Peptidase_M48,TPR_19
WLSH2_k127_3439890_16	1449351.RISW2_06870	5.317e-12	68.0	COG2938@1|root,COG2938@2|Bacteria,1Q6AG@1224|Proteobacteria,2VCGQ@28211|Alphaproteobacteria,4KN1I@93682|Roseivivax	28211|Alphaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sdh5
WLSH2_k127_3439890_10	985867.AEWF01000004_gene320	1.424e-80	275.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,47F5J@766|Rickettsiales	766|Rickettsiales	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
WLSH2_k127_3439890_0	349521.HCH_06999	7.666e-253	821.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1XIES@135619|Oceanospirillales	135619|Oceanospirillales	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N,SWIM
WLSH2_k127_3439890_4	1444711.CCJF01000005_gene1683	4.798e-141	458.0	COG0814@1|root,COG0814@2|Bacteria,2JGM8@204428|Chlamydiae	204428|Chlamydiae	E	Transmembrane amino acid transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	Trp_Tyr_perm
WLSH2_k127_3439890_17	908612.HMPREF9720_1064	5.03e-11	70.0	COG0196@1|root,COG0196@2|Bacteria	2|Bacteria	H	riboflavin kinase activity	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WLSH2_k127_3439890_3	91604.ID47_10220	3.704e-147	482.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,47F33@766|Rickettsiales	766|Rickettsiales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WLSH2_k127_3439890_9	336407.RBE_0823	2.468e-81	285.0	COG4632@1|root,COG4632@2|Bacteria,1NTF0@1224|Proteobacteria	1224|Proteobacteria	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA,SPOR
WLSH2_k127_3439890_11	86106.I862_04800	6.167e-45	166.0	COG1694@1|root,COG1694@2|Bacteria,1Q92Q@1224|Proteobacteria,2VD87@28211|Alphaproteobacteria,47GFU@766|Rickettsiales	766|Rickettsiales	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
WLSH2_k127_3439890_5	244582.JQAK01000001_gene799	3.019e-130	430.0	COG4320@1|root,COG4320@2|Bacteria,1N6EW@1224|Proteobacteria,2TU46@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
WLSH2_k127_3439890_12	985867.AEWF01000001_gene1734	4.567e-38	150.0	COG5452@1|root,COG5452@2|Bacteria,1N12T@1224|Proteobacteria,2UCES@28211|Alphaproteobacteria,47GG6@766|Rickettsiales	766|Rickettsiales	S	Ubiquinol-cytochrome C chaperone	-	-	-	-	-	-	-	-	-	-	-	-	Ubiq_cyt_C_chap
WLSH2_k127_3439890_13	985867.AEWF01000001_gene1735	3.363e-30	128.0	COG1399@1|root,COG1399@2|Bacteria,1Q78P@1224|Proteobacteria,2VDDB@28211|Alphaproteobacteria,47G0Z@766|Rickettsiales	766|Rickettsiales	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
WLSH2_k127_3439890_14	985867.AEWF01000001_gene1929	3.444e-25	105.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,2UKBX@28211|Alphaproteobacteria,47FSZ@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WLSH2_k127_3439890_6	985867.AEWF01000001_gene1928	1.394e-125	410.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2TR53@28211|Alphaproteobacteria,47EYB@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WLSH2_k127_3439890_7	244582.JQAK01000004_gene240	4.856e-119	391.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,47EVU@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WLSH2_k127_3581636_6	2903.EOD32897	3.854e-17	94.0	KOG4308@1|root,KOG4308@2759|Eukaryota	2759|Eukaryota	S	interleukin-8 biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
WLSH2_k127_3581636_0	91604.ID47_09195	1.106e-281	872.0	COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria,47ESY@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
WLSH2_k127_3581636_7	985867.AEWF01000004_gene253	1.882e-10	69.0	2ADX0@1|root,313P4@2|Bacteria,1PSRQ@1224|Proteobacteria,2V4UQ@28211|Alphaproteobacteria,47G5R@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3581636_4	985867.AEWF01000004_gene284	7.258e-104	344.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria,2TU31@28211|Alphaproteobacteria,47F35@766|Rickettsiales	766|Rickettsiales	S	Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
WLSH2_k127_3581636_3	985867.AEWF01000004_gene101	7.153e-105	355.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TRCV@28211|Alphaproteobacteria,47F7V@766|Rickettsiales	766|Rickettsiales	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
WLSH2_k127_3581636_2	1410620.SHLA_7c000630	6.288e-159	515.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2TQVF@28211|Alphaproteobacteria,4B8PW@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
WLSH2_k127_3581636_8	509190.Cseg_4220	8.031e-08	66.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,2KG17@204458|Caulobacterales	204458|Caulobacterales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
WLSH2_k127_3581636_1	985867.AEWF01000003_gene981	1.117e-216	679.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,47F08@766|Rickettsiales	766|Rickettsiales	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
WLSH2_k127_3909915_5	27923.ML223010a-PA	0.0001492	55.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38H8T@33154|Opisthokonta,3BB2P@33208|Metazoa	33208|Metazoa	S	Leucine rich repeat containing 34	LRRC34	-	-	-	-	-	-	-	-	-	-	-	LRR_6
WLSH2_k127_3909915_3	91604.ID47_03960	1.449e-115	377.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,47F1E@766|Rickettsiales	766|Rickettsiales	Q	ABC transporter, permease protein	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WLSH2_k127_3909915_1	244582.JQAK01000001_gene794	3.997e-219	694.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,47ET5@766|Rickettsiales	766|Rickettsiales	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_3909915_4	244582.JQAK01000004_gene301	1.324e-56	201.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2U9U1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WLSH2_k127_3909915_0	985867.AEWF01000004_gene108	5.4e-323	993.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,47EU8@766|Rickettsiales	766|Rickettsiales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	abcT1	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_Xtn
WLSH2_k127_3909915_2	91604.ID47_09420	2.025e-188	598.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria,47EUK@766|Rickettsiales	766|Rickettsiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WLSH2_k127_3943768_1	661367.LLO_0573	7.862e-32	126.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,1S8Z1@1236|Gammaproteobacteria,1JF90@118969|Legionellales	118969|Legionellales	L	GIY-YIG type nucleases (URI domain)	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH2_k127_3943768_0	985867.AEWF01000001_gene1966	3.631e-162	516.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,47EY7@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WLSH2_k127_4386031_1	438753.AZC_0008	2.769e-151	486.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,3EYJ0@335928|Xanthobacteraceae	28211|Alphaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH2_k127_4386031_3	91604.ID47_07800	7.085e-101	343.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2TS9S@28211|Alphaproteobacteria,47F8W@766|Rickettsiales	766|Rickettsiales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
WLSH2_k127_4386031_4	1227739.Hsw_2019	1.007e-24	110.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,47R93@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
WLSH2_k127_4386031_2	315456.RF_0322	2.89e-143	464.0	COG1301@1|root,COG1301@2|Bacteria,1R3SN@1224|Proteobacteria,2U5UF@28211|Alphaproteobacteria,47F6X@766|Rickettsiales	766|Rickettsiales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
WLSH2_k127_4386031_0	985867.AEWF01000004_gene66	1.564e-194	611.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,47EUM@766|Rickettsiales	766|Rickettsiales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH2_k127_4386031_5	5722.XP_001310853.1	1.898e-05	55.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
WLSH2_k127_4408240_4	985867.AEWF01000003_gene811	0.0006317	43.0	2BZT9@1|root,2ZEF7@2|Bacteria,1QVXX@1224|Proteobacteria,2TWM6@28211|Alphaproteobacteria,47FJG@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
WLSH2_k127_4408240_0	91604.ID47_10350	5.529e-98	326.0	COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,2TTDS@28211|Alphaproteobacteria,47F6B@766|Rickettsiales	766|Rickettsiales	S	transport system, ATPase component	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
WLSH2_k127_4408240_2	244582.JQAK01000001_gene1701	1.743e-87	300.0	COG4120@1|root,COG4120@2|Bacteria,1MXGE@1224|Proteobacteria,2TUWW@28211|Alphaproteobacteria,47FE0@766|Rickettsiales	766|Rickettsiales	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
WLSH2_k127_4408240_3	985867.AEWF01000003_gene816	7.481e-83	288.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system periplasmic component	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
WLSH2_k127_4408240_1	244582.JQAK01000001_gene1702	2.135e-90	308.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,47FUT@766|Rickettsiales	766|Rickettsiales	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
WLSH2_k127_4570427_2	91604.ID47_09165	1.275e-58	214.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,47FT6@766|Rickettsiales	766|Rickettsiales	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgD,FlgD_ig
WLSH2_k127_4570427_1	91604.ID47_09160	1.064e-104	354.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2TSF2@28211|Alphaproteobacteria,47FQP@766|Rickettsiales	766|Rickettsiales	N	Flagellar basal body protein FlaE	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bbr_C
WLSH2_k127_4570427_3	985867.AEWF01000002_gene1486	6.494e-51	188.0	COG4968@1|root,COG4968@2|Bacteria,1QUZW@1224|Proteobacteria,2TWJS@28211|Alphaproteobacteria,47GSW@766|Rickettsiales	766|Rickettsiales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4570427_4	1101189.AQUO01000002_gene728	5.57e-08	56.0	COG1961@1|root,COG1961@2|Bacteria,1PFVE@1224|Proteobacteria,2V7HD@28211|Alphaproteobacteria,2PYM2@265|Paracoccus	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Zn_ribbon_recom
WLSH2_k127_4570427_0	985867.AEWF01000009_gene1148	5.281e-142	463.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,47FUW@766|Rickettsiales	766|Rickettsiales	L	impB/mucB/samB family	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
WLSH2_k127_4612458_8	112098.XP_008607560.1	2.542e-20	101.0	COG4886@1|root,KOG0619@2759|Eukaryota	2759|Eukaryota	U	regulation of response to stimulus	LRRC17	GO:0001501,GO:0002376,GO:0002520,GO:0002682,GO:0002683,GO:0002761,GO:0002762,GO:0005575,GO:0005576,GO:0005615,GO:0007275,GO:0008150,GO:0009888,GO:0032501,GO:0032502,GO:0044421,GO:0045595,GO:0045596,GO:0045637,GO:0045638,GO:0045670,GO:0045671,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048539,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0051239,GO:0051241,GO:0060348,GO:0065007,GO:1902105,GO:1902106,GO:1903706,GO:1903707,GO:2000026	4.6.1.1	ko:K01768,ko:K19613	ko00230,ko02025,ko04014,ko04113,ko04213,map00230,map02025,map04014,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	LRRCT,LRR_8
WLSH2_k127_4612458_6	91604.ID47_09120	5.056e-52	197.0	2DN7Z@1|root,32W0X@2|Bacteria,1Q774@1224|Proteobacteria,2VDBM@28211|Alphaproteobacteria,47FWC@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4612458_2	244582.JQAK01000001_gene1119	1.877e-142	456.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,47F0J@766|Rickettsiales	766|Rickettsiales	C	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3	coxC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
WLSH2_k127_4612458_10	701176.VIBRN418_09683	8.72e-05	50.0	2DGAJ@1|root,2ZV5H@2|Bacteria,1P9YV@1224|Proteobacteria,1STCR@1236|Gammaproteobacteria,1Y074@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4612458_4	985867.AEWF01000001_gene1991	1.203e-63	226.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,47FEY@766|Rickettsiales	766|Rickettsiales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WLSH2_k127_4612458_7	244582.JQAK01000001_gene762	4.948e-22	98.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,2UJYU@28211|Alphaproteobacteria,47FSY@766|Rickettsiales	766|Rickettsiales	U	Involved in protein export. Participates in an early event of protein translocation (By similarity)	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
WLSH2_k127_4612458_0	91604.ID47_02460	2.508e-282	874.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,47EU6@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WLSH2_k127_4612458_9	244582.JQAK01000001_gene924	1.413e-19	95.0	COG2062@1|root,COG2062@2|Bacteria,1PRVF@1224|Proteobacteria,2V43E@28211|Alphaproteobacteria,47FRT@766|Rickettsiales	766|Rickettsiales	T	phosphohistidine phosphatase, SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WLSH2_k127_4612458_1	1150469.RSPPHO_01182	1.065e-215	693.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,2JQAT@204441|Rhodospirillales	204441|Rhodospirillales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WLSH2_k127_4612458_5	91604.ID47_09880	2.92e-61	217.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,47FG4@766|Rickettsiales	766|Rickettsiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WLSH2_k127_4612458_3	91604.ID47_09875	7.756e-123	397.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,47EZC@766|Rickettsiales	766|Rickettsiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WLSH2_k127_4639320_1	244582.JQAK01000001_gene1064	5.975e-61	213.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2TS6R@28211|Alphaproteobacteria,47EW7@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
WLSH2_k127_4639320_0	391896.A1I_07205	2.331e-209	662.0	COG3202@1|root,COG3202@2|Bacteria,1MVS9@1224|Proteobacteria,2TSSJ@28211|Alphaproteobacteria,47G4H@766|Rickettsiales	766|Rickettsiales	P	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlcE	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015931,GO:0016020,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
WLSH2_k127_4643225_4	985867.AEWF01000002_gene1405	3.999e-142	470.0	COG1305@1|root,COG1305@2|Bacteria,1R5Q7@1224|Proteobacteria,2TV5A@28211|Alphaproteobacteria,47EYX@766|Rickettsiales	766|Rickettsiales	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857
WLSH2_k127_4643225_5	985867.AEWF01000002_gene1561	1.926e-92	308.0	COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2U10V@28211|Alphaproteobacteria,47F7Z@766|Rickettsiales	766|Rickettsiales	S	Sugar fermentation stimulation protein homolog	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
WLSH2_k127_4643225_6	1120983.KB894570_gene1666	3.885e-80	277.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria,1JN0T@119043|Rhodobiaceae	28211|Alphaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WLSH2_k127_4643225_7	985867.AEWF01000002_gene1506	2.643e-76	264.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,47FB8@766|Rickettsiales	766|Rickettsiales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31,Methyltransf_4
WLSH2_k127_4643225_11	985867.AEWF01000002_gene1532	4.044e-28	115.0	2AEQR@1|root,314MA@2|Bacteria,1PUBJ@1224|Proteobacteria,2V620@28211|Alphaproteobacteria,47GHR@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4643225_10	91604.ID47_04365	1.514e-56	201.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2U5Q5@28211|Alphaproteobacteria,47FKU@766|Rickettsiales	766|Rickettsiales	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
WLSH2_k127_4643225_9	91604.ID47_04360	4.31e-59	209.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2UCHU@28211|Alphaproteobacteria,47FIU@766|Rickettsiales	766|Rickettsiales	Q	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WLSH2_k127_4643225_15	91604.ID47_04355	4.084e-22	101.0	2AKRG@1|root,31BIB@2|Bacteria,1Q7D6@1224|Proteobacteria,2VDI6@28211|Alphaproteobacteria,47GBM@766|Rickettsiales	766|Rickettsiales	S	Uncharacterized protein conserved in bacteria (DUF2155)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2155
WLSH2_k127_4643225_3	91604.ID47_11710	1.118e-146	477.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,47EW1@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
WLSH2_k127_4643225_17	985867.AEWF01000001_gene1942	8.165e-17	85.0	COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,2UA8D@28211|Alphaproteobacteria,47FH4@766|Rickettsiales	766|Rickettsiales	M	COG4520 Surface antigen	omp	-	-	-	-	-	-	-	-	-	-	-	17kDa_Anti_2,Rick_17kDa_Anti
WLSH2_k127_4643225_8	91604.ID47_02295	8.76e-74	257.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2TRPS@28211|Alphaproteobacteria,47G4N@766|Rickettsiales	766|Rickettsiales	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH2_k127_4643225_13	244582.JQAK01000004_gene317	5.885e-25	107.0	COG0721@1|root,COG0721@2|Bacteria,1QE6I@1224|Proteobacteria,2VADW@28211|Alphaproteobacteria,47FQF@766|Rickettsiales	766|Rickettsiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WLSH2_k127_4643225_2	91604.ID47_03735	7.879e-247	769.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria,47F34@766|Rickettsiales	766|Rickettsiales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH2_k127_4643225_1	91604.ID47_03740	1.291e-261	814.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,47EW2@766|Rickettsiales	766|Rickettsiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WLSH2_k127_4643225_19	661367.LLO_0761	4.944e-06	54.0	2APRX@1|root,31EVS@2|Bacteria,1QC85@1224|Proteobacteria,1T7XI@1236|Gammaproteobacteria,1JFZX@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4643225_16	1444711.CCJF01000005_gene919	1.089e-21	101.0	COG3631@1|root,COG3631@2|Bacteria,2JHCY@204428|Chlamydiae	204428|Chlamydiae	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WLSH2_k127_4643225_18	1408445.JHXP01000013_gene2577	2.302e-06	55.0	2APRX@1|root,31EVS@2|Bacteria,1QC85@1224|Proteobacteria,1T7XI@1236|Gammaproteobacteria,1JFZX@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4643225_12	1444711.CCJF01000005_gene920	4.891e-27	118.0	COG1309@1|root,COG1309@2|Bacteria,2JHEE@204428|Chlamydiae	204428|Chlamydiae	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH2_k127_4643225_21	1231626.CAHE_0618	0.0009778	51.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
WLSH2_k127_4643225_0	1123366.TH3_06730	0.0	1137.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2JPMN@204441|Rhodospirillales	204441|Rhodospirillales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH2_k127_4665941_4	1121468.AUBR01000045_gene1803	1.239e-12	70.0	COG1415@1|root,COG1415@2|Bacteria,1UWH7@1239|Firmicutes,24DPJ@186801|Clostridia,42EWV@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
WLSH2_k127_4665941_5	634956.Geoth_1102	5.062e-08	64.0	29610@1|root,2ZTBM@2|Bacteria,1W5TX@1239|Firmicutes	1239|Firmicutes	S	RNase LS, bacterial toxin	-	-	-	-	-	-	-	-	-	-	-	-	RnlA_toxin
WLSH2_k127_4665941_2	401526.TcarDRAFT_1529	4.825e-63	228.0	COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H4G6@909932|Negativicutes	909932|Negativicutes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhC	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WLSH2_k127_4665941_1	368407.Memar_1171	2.098e-71	257.0	COG0457@1|root,arCOG03032@2157|Archaea	2157|Archaea	T	PFAM TPR repeat-containing protein	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	TPR_2,TPR_8
WLSH2_k127_4665941_0	688269.Theth_0193	8.043e-92	309.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_4665941_3	688269.Theth_0192	1.836e-33	135.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH2_k127_4719128_1	439235.Dalk_1526	5.062e-13	70.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
WLSH2_k127_4719128_0	335543.Sfum_1184	2.745e-202	647.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1PFB9@1224|Proteobacteria,437WC@68525|delta/epsilon subdivisions,2X35Z@28221|Deltaproteobacteria,2MS2F@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4827228_0	857087.Metme_2040	1.797e-66	229.0	COG0221@1|root,COG0221@2|Bacteria,1RGCP@1224|Proteobacteria,1SP0T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
WLSH2_k127_4827228_1	1116472.MGMO_83c00210	3.352e-48	173.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,1TKPU@1236|Gammaproteobacteria,1XGHN@135618|Methylococcales	135618|Methylococcales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WLSH2_k127_4877798_0	985867.AEWF01000001_gene1779	1.099e-56	200.0	COG3773@1|root,COG3773@2|Bacteria,1RH3D@1224|Proteobacteria,2UAUQ@28211|Alphaproteobacteria,47G6J@766|Rickettsiales	766|Rickettsiales	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
WLSH2_k127_4877798_1	244582.JQAK01000001_gene861	1.251e-28	117.0	2DPV5@1|root,333HH@2|Bacteria,1NCA9@1224|Proteobacteria,2UHMY@28211|Alphaproteobacteria,47FF4@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4991173_1	985867.AEWF01000007_gene441	1.361e-307	948.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,47EWK@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WLSH2_k127_4991173_3	435832.HMPREF0604_01421	2.23e-30	138.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KQPW@206351|Neisseriales	206351|Neisseriales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
WLSH2_k127_4991173_2	5821.PBANKA_134030	1.358e-78	277.0	COG0462@1|root,KOG1448@2759|Eukaryota,3Y9IE@5794|Apicomplexa,3KANX@422676|Aconoidasida,3YXPY@5819|Haemosporida	422676|Aconoidasida	EF	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WLSH2_k127_4991173_0	91604.ID47_01750	0.0	1037.0	COG2185@1|root,COG2185@2|Bacteria,1QU3N@1224|Proteobacteria,2TVY1@28211|Alphaproteobacteria,47FYT@766|Rickettsiales	766|Rickettsiales	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
WLSH2_k127_4991173_4	1105110.MC5_05550	1.035e-06	59.0	2DPPW@1|root,332XD@2|Bacteria,1QVXZ@1224|Proteobacteria,2TWM8@28211|Alphaproteobacteria,47FQB@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF2608)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2608
WLSH2_k127_5044619_6	91604.ID47_00310	1.785e-79	278.0	COG1073@1|root,COG1073@2|Bacteria,1PS6S@1224|Proteobacteria,2V4DS@28211|Alphaproteobacteria,47FWU@766|Rickettsiales	766|Rickettsiales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
WLSH2_k127_5044619_5	1206737.BAGF01000145_gene5772	2.675e-82	287.0	COG0662@1|root,COG0662@2|Bacteria,2I519@201174|Actinobacteria,4G649@85025|Nocardiaceae	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_5044619_9	1343740.M271_48185	2.674e-65	236.0	COG0079@1|root,COG0079@2|Bacteria,2I9R2@201174|Actinobacteria	201174|Actinobacteria	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_5044619_2	1173028.ANKO01000058_gene3036	7.495e-153	505.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_7,PAS_8,PAS_9,Response_reg
WLSH2_k127_5044619_10	91604.ID47_07615	1.537e-62	231.0	COG1181@1|root,COG1181@2|Bacteria,1QVXS@1224|Proteobacteria,2UTY6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp
WLSH2_k127_5044619_4	91604.ID47_08795	9.235e-84	281.0	COG2173@1|root,COG2173@2|Bacteria,1RENK@1224|Proteobacteria,2TRK8@28211|Alphaproteobacteria,47FWT@766|Rickettsiales	766|Rickettsiales	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
WLSH2_k127_5044619_13	985867.AEWF01000012_gene1316	3.411e-13	83.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	PG_binding_1,Sel1
WLSH2_k127_5044619_12	985867.AEWF01000005_gene2411	9.487e-24	100.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,2TUNY@28211|Alphaproteobacteria,47FWE@766|Rickettsiales	766|Rickettsiales	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5044619_7	985867.AEWF01000004_gene165	2.564e-69	242.0	COG0546@1|root,COG0546@2|Bacteria,1RDW2@1224|Proteobacteria,2U7C9@28211|Alphaproteobacteria,47FFM@766|Rickettsiales	766|Rickettsiales	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WLSH2_k127_5044619_14	4533.OB08G25140.1	8.042e-13	78.0	COG0588@1|root,KOG0235@2759|Eukaryota,37J1U@33090|Viridiplantae,3GEKA@35493|Streptophyta,3KVV4@4447|Liliopsida,3IETK@38820|Poales	35493|Streptophyta	G	Histidine phosphatase superfamily (branch 1)	-	GO:0003674,GO:0003824,GO:0004647,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0070178,GO:0070179,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WLSH2_k127_5044619_1	985867.AEWF01000004_gene83	6.071e-162	518.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TSUZ@28211|Alphaproteobacteria,47FB0@766|Rickettsiales	766|Rickettsiales	E	Required for the activity of the bacterial periplasmic transport system of putrescine	-	-	-	ko:K11073	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	SBP_bac_6,SBP_bac_8
WLSH2_k127_5044619_0	985867.AEWF01000004_gene70	6.316e-206	649.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria,47F0T@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WLSH2_k127_5044619_8	985867.AEWF01000004_gene69	3.011e-68	235.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,47FC2@766|Rickettsiales	766|Rickettsiales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WLSH2_k127_5044619_3	331113.SNE_A22960	7.867e-139	456.0	COG1672@1|root,COG1672@2|Bacteria,2JGKE@204428|Chlamydiae	2|Bacteria	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
WLSH2_k127_5044619_11	421052.F945_00023	5.657e-59	210.0	COG3738@1|root,COG3738@2|Bacteria,1RE1M@1224|Proteobacteria,1S44B@1236|Gammaproteobacteria,3NKTP@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1287)	yijF	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
WLSH2_k127_5044619_15	86106.I862_01195	5.344e-06	55.0	COG0265@1|root,COG0265@2|Bacteria,1RBDX@1224|Proteobacteria,2U6E8@28211|Alphaproteobacteria,47F6D@766|Rickettsiales	766|Rickettsiales	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_5059158_9	91604.ID47_03650	5.934e-67	237.0	COG2602@1|root,COG2602@2|Bacteria,1NWXE@1224|Proteobacteria,2TTNH@28211|Alphaproteobacteria,47FBM@766|Rickettsiales	766|Rickettsiales	V	Penicillin binding protein transpeptidase domain	blaD	-	3.5.2.6	ko:K17838	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Transpeptidase
WLSH2_k127_5059158_4	1380394.JADL01000009_gene3188	1.416e-161	520.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,2JQ3D@204441|Rhodospirillales	204441|Rhodospirillales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
WLSH2_k127_5059158_11	91604.ID47_05860	1.177e-32	128.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupA	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WLSH2_k127_5059158_12	244582.JQAK01000001_gene1455	4.258e-27	113.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WLSH2_k127_5059158_2	244582.JQAK01000001_gene1456	2.588e-165	529.0	COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2TSKU@28211|Alphaproteobacteria,47EYP@766|Rickettsiales	766|Rickettsiales	C	reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
WLSH2_k127_5059158_3	91604.ID47_00350	6.837e-163	519.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2TSM0@28211|Alphaproteobacteria,47ETR@766|Rickettsiales	766|Rickettsiales	D	Belongs to the SEDS family. MrdB RodA subfamily	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WLSH2_k127_5059158_13	661367.LLO_1873	2.072e-25	106.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1JFGW@118969|Legionellales	118969|Legionellales	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
WLSH2_k127_5059158_6	1230343.CANP01000021_gene1429	1.178e-118	389.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1JFGW@118969|Legionellales	118969|Legionellales	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
WLSH2_k127_5059158_1	596153.Alide_2301	1.625e-190	602.0	COG0446@1|root,COG0446@2|Bacteria,1PP77@1224|Proteobacteria,2W9FF@28216|Betaproteobacteria,4AA7E@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_5059158_0	985867.AEWF01000001_gene2254	0.0	1395.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,47EX4@766|Rickettsiales	766|Rickettsiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K18138,ko:K18989	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718,M00720	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.30	-	-	ACR_tran
WLSH2_k127_5059158_7	985867.AEWF01000001_gene2253	8.855e-116	384.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,47FX6@766|Rickettsiales	766|Rickettsiales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WLSH2_k127_5059158_8	244582.JQAK01000001_gene935	1.978e-95	329.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	MA20_05655	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH2_k127_5059158_5	985867.AEWF01000001_gene2239	1.391e-129	429.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2TRMX@28211|Alphaproteobacteria,47F9M@766|Rickettsiales	766|Rickettsiales	S	Peptidase, M16 family	-	-	-	ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH2_k127_5059158_10	985867.AEWF01000001_gene2237	1.114e-58	207.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria,47FQG@766|Rickettsiales	766|Rickettsiales	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WLSH2_k127_5059158_15	257310.BB3159	1.012e-19	90.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,2VRK1@28216|Betaproteobacteria,3T969@506|Alcaligenaceae	28216|Betaproteobacteria	K	regulator	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
WLSH2_k127_5059163_5	748280.NH8B_1804	6.974e-211	671.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH41@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase	phbC2	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PHBC_N,PhaC_N
WLSH2_k127_5059163_60	9597.XP_008949701.1	1.916e-08	68.0	COG0326@1|root,KOG1216@1|root,KOG0019@2759|Eukaryota,KOG1216@2759|Eukaryota,38BYG@33154|Opisthokonta,3BBY5@33208|Metazoa,3CRZ6@33213|Bilateria,4839A@7711|Chordata,495CX@7742|Vertebrata,3JDKW@40674|Mammalia,35MYM@314146|Euarchontoglires,4MAW0@9443|Primates,4N7ZJ@9604|Hominidae	33208|Metazoa	VW	C8	MUC19	GO:0005575,GO:0005576	-	ko:K03900,ko:K10955,ko:K13908,ko:K21125,ko:K22020	ko04151,ko04510,ko04512,ko04610,ko04611,ko04657,ko04970,ko05146,ko05165,ko05226,map04151,map04510,map04512,map04610,map04611,map04657,map04970,map05146,map05165,map05226	-	-	-	ko00000,ko00001,ko03110,ko04131,ko04147,ko04516	-	-	-	C8,TIL,VWD
WLSH2_k127_5059163_61	224914.BMEI1830	4.924e-07	60.0	COG3637@1|root,COG3637@2|Bacteria,1NJWW@1224|Proteobacteria,2UD8G@28211|Alphaproteobacteria,1J3UZ@118882|Brucellaceae	28211|Alphaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
WLSH2_k127_5059163_8	216142.LT40_09225	1.165e-186	594.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	phosphomannomutase	xanA	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH2_k127_5059163_35	91604.ID47_06530	1.88e-61	224.0	COG1286@1|root,COG1286@2|Bacteria	2|Bacteria	S	toxin biosynthetic process	cvpA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
WLSH2_k127_5059163_15	244582.JQAK01000001_gene1410	1.51e-145	473.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,47FF2@766|Rickettsiales	766|Rickettsiales	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
WLSH2_k127_5059163_6	985867.AEWF01000001_gene1723	6.708e-202	638.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,47ETV@766|Rickettsiales	766|Rickettsiales	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WLSH2_k127_5059163_11	91604.ID47_08045	8.666e-151	502.0	COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,47F86@766|Rickettsiales	766|Rickettsiales	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
WLSH2_k127_5059163_45	45351.EDO45781	2e-30	132.0	COG3475@1|root,2SCGN@2759|Eukaryota,3ACHR@33154|Opisthokonta,3BWMA@33208|Metazoa	33208|Metazoa	M	LicD family	-	-	-	-	-	-	-	-	-	-	-	-	LicD
WLSH2_k127_5059163_9	985867.AEWF01000003_gene820	5.132e-177	577.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,2TW2Q@28211|Alphaproteobacteria,47GTM@766|Rickettsiales	766|Rickettsiales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
WLSH2_k127_5059163_39	91604.ID47_10375	4.167e-42	161.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2UBYU@28211|Alphaproteobacteria,47FMQ@766|Rickettsiales	766|Rickettsiales	C	Cytochrome b561	cybB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
WLSH2_k127_5059163_27	985867.AEWF01000003_gene818	3.124e-92	314.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria,47FDS@766|Rickettsiales	766|Rickettsiales	I	Alpha/beta hydrolase family	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
WLSH2_k127_5059163_38	985867.AEWF01000003_gene918	3.404e-44	167.0	COG2854@1|root,COG2854@2|Bacteria,1PDBV@1224|Proteobacteria,2U5HR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
WLSH2_k127_5059163_55	244582.JQAK01000001_gene1806	1.832e-15	80.0	COG5336@1|root,COG5336@2|Bacteria,1Q3U7@1224|Proteobacteria,2UJSQ@28211|Alphaproteobacteria,47GNY@766|Rickettsiales	766|Rickettsiales	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
WLSH2_k127_5059163_23	985867.AEWF01000003_gene901	6.869e-113	370.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,47EYQ@766|Rickettsiales	766|Rickettsiales	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WLSH2_k127_5059163_41	91604.ID47_11060	3.321e-34	132.0	COG0636@1|root,COG0636@2|Bacteria,1PMN4@1224|Proteobacteria,2V08B@28211|Alphaproteobacteria,47FQ8@766|Rickettsiales	766|Rickettsiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WLSH2_k127_5059163_48	985867.AEWF01000003_gene899	5.214e-24	109.0	COG0711@1|root,COG0711@2|Bacteria,1Q76H@1224|Proteobacteria,2VDAY@28211|Alphaproteobacteria,47FU5@766|Rickettsiales	766|Rickettsiales	C	COG0711 F0F1-type ATP synthase, subunit b	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B,YMF19
WLSH2_k127_5059163_49	91604.ID47_11050	1.138e-18	93.0	2AEGF@1|root,314BI@2|Bacteria,1PTVM@1224|Proteobacteria,2V5PT@28211|Alphaproteobacteria,47GA5@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5059163_3	985867.AEWF01000002_gene1380	7.825e-262	818.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,47F2Q@766|Rickettsiales	766|Rickettsiales	L	Single-stranded-DNA-specific exonuclease (RecJ)	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH2_k127_5059163_44	570417.WP0261	6.207e-32	126.0	COG1672@1|root,COG1672@2|Bacteria,1MWJX@1224|Proteobacteria,2V4HQ@28211|Alphaproteobacteria,47FYU@766|Rickettsiales	766|Rickettsiales	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2
WLSH2_k127_5059163_22	1144888.CM001467_gene914	1.284e-118	393.0	COG1373@1|root,COG1373@2|Bacteria,1NQGE@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
WLSH2_k127_5059163_62	91604.ID47_10860	1.962e-05	50.0	2BIKX@1|root,32CTT@2|Bacteria,1Q83C@1224|Proteobacteria,2V769@28211|Alphaproteobacteria,47GMU@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5059163_2	985867.AEWF01000002_gene1382	1.122e-284	886.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,47EXF@766|Rickettsiales	766|Rickettsiales	I	Poly(3-hydroxyalkanoate) synthetase	phbC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
WLSH2_k127_5059163_43	244581.IM40_06825	9.908e-34	141.0	COG5599@1|root,COG5599@2|Bacteria,1QU22@1224|Proteobacteria,2TXC7@28211|Alphaproteobacteria,47GTG@766|Rickettsiales	1224|Proteobacteria	T	Inositol hexakisphosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTPlike_phytase
WLSH2_k127_5059163_40	244581.IM40_06825	2.191e-38	155.0	COG5599@1|root,COG5599@2|Bacteria,1QU22@1224|Proteobacteria,2TXC7@28211|Alphaproteobacteria,47GTG@766|Rickettsiales	1224|Proteobacteria	T	Inositol hexakisphosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTPlike_phytase
WLSH2_k127_5059163_46	244581.IM40_06825	7.14e-30	131.0	COG5599@1|root,COG5599@2|Bacteria,1QU22@1224|Proteobacteria,2TXC7@28211|Alphaproteobacteria,47GTG@766|Rickettsiales	1224|Proteobacteria	T	Inositol hexakisphosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTPlike_phytase
WLSH2_k127_5059163_52	1123511.KB905859_gene2204	6.825e-18	95.0	COG5599@1|root,COG5599@2|Bacteria,1V8D3@1239|Firmicutes,4H3GG@909932|Negativicutes	909932|Negativicutes	T	Inositol hexakisphosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTPlike_phytase
WLSH2_k127_5059163_42	244581.IM40_06825	4.946e-34	143.0	COG5599@1|root,COG5599@2|Bacteria,1QU22@1224|Proteobacteria,2TXC7@28211|Alphaproteobacteria,47GTG@766|Rickettsiales	1224|Proteobacteria	T	Inositol hexakisphosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTPlike_phytase
WLSH2_k127_5059163_29	244582.JQAK01000001_gene1207	5.587e-89	297.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria,47GC8@766|Rickettsiales	766|Rickettsiales	S	metal ion binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WLSH2_k127_5059163_25	985867.AEWF01000001_gene2283	2.442e-103	352.0	COG0642@1|root,COG0642@2|Bacteria,1QU3Y@1224|Proteobacteria,2TVYH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WLSH2_k127_5059163_34	244582.JQAK01000001_gene1209	1.407e-67	237.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2TSK7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	regA	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
WLSH2_k127_5059163_33	985867.AEWF01000006_gene604	1.984e-74	256.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria,47FJY@766|Rickettsiales	766|Rickettsiales	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WLSH2_k127_5059163_1	985867.AEWF01000006_gene605	1.515e-293	911.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,47EU9@766|Rickettsiales	766|Rickettsiales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WLSH2_k127_5059163_17	985867.AEWF01000003_gene811	3.692e-137	450.0	2BZT9@1|root,2ZEF7@2|Bacteria,1QVXX@1224|Proteobacteria,2TWM6@28211|Alphaproteobacteria,47FJG@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
WLSH2_k127_5059163_14	91604.ID47_09865	7.852e-146	479.0	COG3202@1|root,COG3202@2|Bacteria,1MVS9@1224|Proteobacteria,2TSSJ@28211|Alphaproteobacteria,47EX6@766|Rickettsiales	766|Rickettsiales	C	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlc1	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006862,GO:0008150,GO:0015711,GO:0015748,GO:0015865,GO:0015867,GO:0015868,GO:0015893,GO:0015931,GO:0016020,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051503,GO:0071702,GO:0071705,GO:0071944,GO:1901264	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
WLSH2_k127_5059163_51	91604.ID47_05680	3.736e-18	89.0	COG5622@1|root,COG5622@2|Bacteria,1Q7BP@1224|Proteobacteria,2VDGD@28211|Alphaproteobacteria,47G8B@766|Rickettsiales	766|Rickettsiales	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
WLSH2_k127_5059163_30	985867.AEWF01000001_gene2232	6.319e-87	315.0	2BSBU@1|root,32MDP@2|Bacteria,1Q8KU@1224|Proteobacteria,2V7C7@28211|Alphaproteobacteria,47FWH@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5059163_58	390333.Ldb0032	4.815e-09	67.0	COG0515@1|root,COG0515@2|Bacteria,1TSH3@1239|Firmicutes,4HGIJ@91061|Bacilli,3F7MT@33958|Lactobacillaceae	91061|Bacilli	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like,Pkinase
WLSH2_k127_5059163_13	985867.AEWF01000003_gene778	4.803e-147	471.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,47F1N@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
WLSH2_k127_5059163_19	244582.JQAK01000001_gene1792	4.664e-124	409.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2TS37@28211|Alphaproteobacteria,47EVA@766|Rickettsiales	766|Rickettsiales	M	Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide- 1,4'-bisphosphate precursor of lipid A	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
WLSH2_k127_5059163_32	91604.ID47_10190	5.539e-80	278.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2TTZ4@28211|Alphaproteobacteria,47F5U@766|Rickettsiales	766|Rickettsiales	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
WLSH2_k127_5059163_31	985867.AEWF01000003_gene967	4.017e-81	281.0	COG3660@1|root,COG3660@2|Bacteria,1RH27@1224|Proteobacteria,2VG34@28211|Alphaproteobacteria,47GSB@766|Rickettsiales	766|Rickettsiales	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
WLSH2_k127_5059163_37	713586.KB900536_gene1646	5.138e-51	188.0	29P18@1|root,309ZE@2|Bacteria,1RF28@1224|Proteobacteria,1SKWV@1236|Gammaproteobacteria,1X0FG@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5059163_0	91604.ID47_11185	0.0	1006.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,47EUE@766|Rickettsiales	766|Rickettsiales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WLSH2_k127_5059163_12	251229.Chro_1886	1.26e-149	496.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3VIJ3@52604|Pleurocapsales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GGDEF,PAS_3,Response_reg
WLSH2_k127_5059163_24	1244869.H261_04208	1.281e-111	371.0	COG3287@1|root,COG3287@2|Bacteria	2|Bacteria	M	FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
WLSH2_k127_5059163_28	985867.AEWF01000003_gene987	1.033e-89	301.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2TS8J@28211|Alphaproteobacteria,47FCM@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WLSH2_k127_5059163_54	91604.ID47_04680	4.683e-16	92.0	2AKME@1|root,31BDW@2|Bacteria,1Q78J@1224|Proteobacteria,2VDD7@28211|Alphaproteobacteria,47G0J@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5059163_10	91604.ID47_04685	3.94e-161	513.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,47EX3@766|Rickettsiales	766|Rickettsiales	S	Enoyl-(Acyl-carrier-protein) reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
WLSH2_k127_5059163_21	985867.AEWF01000004_gene238	2.117e-119	398.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,47F22@766|Rickettsiales	766|Rickettsiales	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
WLSH2_k127_5059163_26	985867.AEWF01000004_gene237	1.443e-99	331.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,47F68@766|Rickettsiales	766|Rickettsiales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,Methyltransf_11,Methyltransf_23
WLSH2_k127_5059163_53	1485545.JQLW01000009_gene86	4.692e-17	85.0	COG1708@1|root,COG1708@2|Bacteria,1N7SN@1224|Proteobacteria	1224|Proteobacteria	S	PFAM DNA polymerase, beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH2_k127_5059163_16	91604.ID47_11870	3.282e-143	464.0	COG1301@1|root,COG1301@2|Bacteria,1R3SN@1224|Proteobacteria,2U5UF@28211|Alphaproteobacteria,47F6X@766|Rickettsiales	766|Rickettsiales	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
WLSH2_k127_5059163_18	985867.AEWF01000004_gene205	1.454e-136	472.0	COG3164@1|root,COG3164@2|Bacteria,1MVDY@1224|Proteobacteria,2TSGG@28211|Alphaproteobacteria,47F6Q@766|Rickettsiales	766|Rickettsiales	S	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
WLSH2_k127_5059163_7	985867.AEWF01000001_gene1921	7.859e-192	611.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,47EZF@766|Rickettsiales	766|Rickettsiales	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
WLSH2_k127_5059163_50	985867.AEWF01000003_gene929	2.424e-18	91.0	2E5SK@1|root,3196Q@2|Bacteria,1Q1XI@1224|Proteobacteria,2V63B@28211|Alphaproteobacteria,47GIS@766|Rickettsiales	766|Rickettsiales	N	Class II flagellar assembly regulator	-	-	-	-	-	-	-	-	-	-	-	-	FliX
WLSH2_k127_5059163_36	86106.I862_02180	1.012e-54	197.0	COG1051@1|root,COG1051@2|Bacteria,1RKG8@1224|Proteobacteria,2UCMT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_5059163_56	172088.AUGA01000004_gene3944	3.825e-11	64.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,3JQP3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WLSH2_k127_5059163_20	91604.ID47_06440	4.082e-120	393.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,47EXB@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WLSH2_k127_5059163_4	244582.JQAK01000001_gene954	7.878e-221	694.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,47EYW@766|Rickettsiales	766|Rickettsiales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M,Zn_ribbon_recom
WLSH2_k127_5059163_47	985867.AEWF01000001_gene2063	2.156e-28	117.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria,47FAG@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WLSH2_k127_5061706_12	985867.AEWF01000003_gene1006	3.493e-29	122.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2UCJF@28211|Alphaproteobacteria,47FKM@766|Rickettsiales	766|Rickettsiales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WLSH2_k127_5061706_0	244582.JQAK01000001_gene2153	0.0	1109.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,47F21@766|Rickettsiales	766|Rickettsiales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
WLSH2_k127_5061706_1	985867.AEWF01000003_gene1004	1.019e-227	716.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,47EVY@766|Rickettsiales	766|Rickettsiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
WLSH2_k127_5061706_8	244582.JQAK01000001_gene2155	3.791e-49	179.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,47FMI@766|Rickettsiales	766|Rickettsiales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
WLSH2_k127_5061706_3	985867.AEWF01000004_gene254	5.969e-146	467.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,2TSQD@28211|Alphaproteobacteria,47EZ5@766|Rickettsiales	766|Rickettsiales	G	fructose-bisphosphate aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
WLSH2_k127_5061706_5	985867.AEWF01000004_gene255	1.91e-91	304.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,47F73@766|Rickettsiales	766|Rickettsiales	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WLSH2_k127_5061706_4	985867.AEWF01000004_gene256	1.453e-116	381.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,47F9T@766|Rickettsiales	766|Rickettsiales	G	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WLSH2_k127_5061706_2	91604.ID47_03350	9.561e-205	643.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,47EYJ@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WLSH2_k127_5061706_6	244582.JQAK01000001_gene740	5.038e-53	193.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,47FG1@766|Rickettsiales	766|Rickettsiales	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WLSH2_k127_5061706_10	244582.JQAK01000001_gene743	4.027e-34	133.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria,47FM3@766|Rickettsiales	766|Rickettsiales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WLSH2_k127_5061706_7	244582.JQAK01000001_gene744	5.461e-52	186.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria,47FKY@766|Rickettsiales	766|Rickettsiales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WLSH2_k127_5061706_13	118161.KB235919_gene6419	2.549e-13	72.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5061706_14	663321.REG_1996	0.000213	46.0	COG3464@1|root,COG3464@2|Bacteria,1MX7Z@1224|Proteobacteria,1RQ4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5061706_9	118161.KB235919_gene6419	3.662e-40	158.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5061706_11	985867.AEWF01000002_gene1400	5.794e-30	136.0	2AKVW@1|root,31BP3@2|Bacteria,1Q7IP@1224|Proteobacteria,2VDPZ@28211|Alphaproteobacteria,47GN7@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5098174_2	985867.AEWF01000003_gene712	5.782e-78	267.0	COG1121@1|root,COG1121@2|Bacteria,1MW47@1224|Proteobacteria,2TRJA@28211|Alphaproteobacteria,47FFB@766|Rickettsiales	766|Rickettsiales	P	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_5098174_0	91604.ID47_09585	2.53e-124	404.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2TS2V@28211|Alphaproteobacteria,47F4Z@766|Rickettsiales	766|Rickettsiales	U	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
WLSH2_k127_5098174_1	985867.AEWF01000001_gene1997	3.573e-114	376.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2TTW2@28211|Alphaproteobacteria,47FAY@766|Rickettsiales	766|Rickettsiales	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
WLSH2_k127_5098174_3	91604.ID47_02440	3.172e-24	102.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2TR5A@28211|Alphaproteobacteria,47F55@766|Rickettsiales	766|Rickettsiales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
WLSH2_k127_5129671_20	985867.AEWF01000002_gene1489	3.045e-36	139.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,47F0F@766|Rickettsiales	766|Rickettsiales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WLSH2_k127_5129671_7	91604.ID47_11945	1.605e-113	372.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,47F6G@766|Rickettsiales	766|Rickettsiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WLSH2_k127_5129671_0	985867.AEWF01000002_gene1487	3.535e-271	841.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,47ETU@766|Rickettsiales	766|Rickettsiales	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WLSH2_k127_5129671_5	91604.ID47_11445	5.902e-116	382.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,47G10@766|Rickettsiales	766|Rickettsiales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	-	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
WLSH2_k127_5129671_10	985867.AEWF01000001_gene2332	2.809e-84	294.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,47F80@766|Rickettsiales	766|Rickettsiales	H	Probable RNA and SrmB- binding site of polymerase A	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd
WLSH2_k127_5129671_19	91604.ID47_11840	5.158e-38	151.0	2AJVV@1|root,31AIM@2|Bacteria,1Q5QP@1224|Proteobacteria,2VC1I@28211|Alphaproteobacteria,47G53@766|Rickettsiales	766|Rickettsiales	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
WLSH2_k127_5129671_21	985867.AEWF01000004_gene201	5.762e-34	140.0	2AJVV@1|root,31AIM@2|Bacteria,1Q5QP@1224|Proteobacteria,2VC1I@28211|Alphaproteobacteria,47G53@766|Rickettsiales	766|Rickettsiales	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
WLSH2_k127_5129671_1	985867.AEWF01000001_gene1831	1.668e-261	819.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,47F25@766|Rickettsiales	766|Rickettsiales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WLSH2_k127_5129671_12	91604.ID47_02260	1.564e-66	233.0	COG2941@1|root,COG2941@2|Bacteria,1RAK4@1224|Proteobacteria,2U85I@28211|Alphaproteobacteria,47FI6@766|Rickettsiales	766|Rickettsiales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
WLSH2_k127_5129671_18	1197906.CAJQ02000024_gene1397	6.992e-40	151.0	COG0599@1|root,COG0599@2|Bacteria,1MZ80@1224|Proteobacteria,2UDE8@28211|Alphaproteobacteria,3JZ0Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WLSH2_k127_5129671_15	380394.Lferr_0210	1.844e-51	184.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1T9P7@1236|Gammaproteobacteria,2NDUI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WLSH2_k127_5129671_14	91604.ID47_02025	8.602e-53	200.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	ymfM	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
WLSH2_k127_5129671_8	91604.ID47_08710	9.183e-101	336.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,47F8R@766|Rickettsiales	766|Rickettsiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WLSH2_k127_5129671_6	91604.ID47_08705	1.249e-115	387.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2TSJ3@28211|Alphaproteobacteria,47FMF@766|Rickettsiales	766|Rickettsiales	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N,SurA_N_3
WLSH2_k127_5129671_9	91604.ID47_08700	6.765e-90	312.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2TQUB@28211|Alphaproteobacteria,47FE4@766|Rickettsiales	766|Rickettsiales	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WLSH2_k127_5129671_4	91604.ID47_08695	2.62e-128	425.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,47F8I@766|Rickettsiales	766|Rickettsiales	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WLSH2_k127_5129671_2	91604.ID47_08690	4.098e-240	765.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,47F1W@766|Rickettsiales	766|Rickettsiales	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
WLSH2_k127_5129671_11	985867.AEWF01000001_gene1939	2.119e-78	265.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,47FC5@766|Rickettsiales	766|Rickettsiales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WLSH2_k127_5129671_17	985867.AEWF01000001_gene1793	4.802e-42	159.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2U7A4@28211|Alphaproteobacteria,47G8S@766|Rickettsiales	766|Rickettsiales	L	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WLSH2_k127_5129671_13	91604.ID47_06270	1.093e-53	192.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,2U728@28211|Alphaproteobacteria,47G8A@766|Rickettsiales	766|Rickettsiales	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
WLSH2_k127_5129671_16	985867.AEWF01000001_gene1905	3.512e-48	188.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,47F2K@766|Rickettsiales	766|Rickettsiales	C	COG1294 Cytochrome bd-type quinol oxidase, subunit 2	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
WLSH2_k127_5129671_3	985867.AEWF01000001_gene1994	4.324e-145	465.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,47EY9@766|Rickettsiales	766|Rickettsiales	M	Belongs to the KdsA family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
WLSH2_k127_5129671_22	1538644.KO02_08780	2.653e-25	121.0	COG3621@1|root,COG3621@2|Bacteria,4NG71@976|Bacteroidetes,1IQQH@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WLSH2_k127_5129671_23	313594.PI23P_10780	9.312e-22	109.0	COG3621@1|root,COG3621@2|Bacteria,4NG71@976|Bacteroidetes,1HY7V@117743|Flavobacteriia	976|Bacteroidetes	S	COG3621 Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WLSH2_k127_5233852_0	1430440.MGMSRv2_0800	1.171e-184	609.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,2JPPJ@204441|Rhodospirillales	204441|Rhodospirillales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
WLSH2_k127_5233852_1	985867.AEWF01000003_gene973	2.547e-157	501.0	COG2267@1|root,COG2267@2|Bacteria,1QU3E@1224|Proteobacteria,2TVXS@28211|Alphaproteobacteria,47F2I@766|Rickettsiales	766|Rickettsiales	I	Alpha/beta hydrolase family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
WLSH2_k127_5286427_0	91604.ID47_06745	0.0	1086.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,47EUT@766|Rickettsiales	766|Rickettsiales	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WLSH2_k127_5286427_5	244582.JQAK01000001_gene2161	2.819e-42	159.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2UBQ9@28211|Alphaproteobacteria,47FP5@766|Rickettsiales	766|Rickettsiales	S	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity)	tsaE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WLSH2_k127_5286427_2	1123261.AXDW01000013_gene3512	4.338e-94	319.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T1I4@1236|Gammaproteobacteria,1X2XB@135614|Xanthomonadales	135614|Xanthomonadales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
WLSH2_k127_5286427_1	1057002.KB905370_gene4948	3.71e-128	424.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,4B7FQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	rkpK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WLSH2_k127_5286427_3	244582.JQAK01000001_gene1216	1.497e-70	247.0	COG0500@1|root,COG2226@2|Bacteria,1NA7K@1224|Proteobacteria,2TT7T@28211|Alphaproteobacteria,47FR2@766|Rickettsiales	766|Rickettsiales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_5286427_4	985867.AEWF01000002_gene1466	4.476e-48	178.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2VAAA@28211|Alphaproteobacteria,47G64@766|Rickettsiales	766|Rickettsiales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WLSH2_k127_5367537_0	985867.AEWF01000001_gene2164	1.234e-99	329.0	COG0765@1|root,COG0765@2|Bacteria,1N786@1224|Proteobacteria,2TRW3@28211|Alphaproteobacteria,47GQG@766|Rickettsiales	766|Rickettsiales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
WLSH2_k127_5367537_1	985867.AEWF01000001_gene2165	8.441e-86	289.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,47F84@766|Rickettsiales	766|Rickettsiales	E	COG1126 ABC-type polar amino acid transport system, ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
WLSH2_k127_5367537_2	980584.AFPB01000149_gene521	1.811e-35	144.0	COG1443@1|root,COG1443@2|Bacteria,4NFJV@976|Bacteroidetes,1HXIQ@117743|Flavobacteriia,406DD@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	I	NUDIX domain	idi	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
WLSH2_k127_5368693_20	1158292.JPOE01000005_gene286	1.463e-07	59.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,1KKAX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
WLSH2_k127_5368693_6	1121033.AUCF01000003_gene3311	5.347e-91	309.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,2JPV4@204441|Rhodospirillales	204441|Rhodospirillales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
WLSH2_k127_5368693_15	211586.SO_0341	2.585e-36	153.0	COG2202@1|root,COG3292@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3292@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q8ZG@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Two component regulator three Y domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Reg_prop,Y_Y_Y
WLSH2_k127_5368693_3	187272.Mlg_1207	5.38e-131	432.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,1SKFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	glutamate--cysteine ligase	gsh1	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
WLSH2_k127_5368693_16	1144312.PMI09_02499	3.18e-33	134.0	COG0607@1|root,COG0607@2|Bacteria,1RDIR@1224|Proteobacteria,2U820@28211|Alphaproteobacteria,4BFT1@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Protein of unknown function (DUF2892)	ygaP	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
WLSH2_k127_5368693_18	244582.JQAK01000001_gene1860	1.286e-23	100.0	COG3293@1|root,COG3293@2|Bacteria,1Q8IA@1224|Proteobacteria,2UWD1@28211|Alphaproteobacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
WLSH2_k127_5368693_19	91604.ID47_11465	1.549e-09	64.0	29F04@1|root,301XX@2|Bacteria,1PU5K@1224|Proteobacteria,2V5XC@28211|Alphaproteobacteria,47GEM@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5368693_11	91604.ID47_11480	6.675e-69	248.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria	1224|Proteobacteria	U	Type II secretion system	pilC2	-	-	ko:K02505,ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WLSH2_k127_5368693_5	244582.JQAK01000004_gene332	3.868e-117	397.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,47EVD@766|Rickettsiales	766|Rickettsiales	NU	Type II/IV secretion system protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH2_k127_5368693_1	91604.ID47_00660	1.341e-151	485.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2TQZX@28211|Alphaproteobacteria,47EXP@766|Rickettsiales	766|Rickettsiales	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WLSH2_k127_5368693_2	91604.ID47_00665	3.796e-140	459.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria,47FJS@766|Rickettsiales	766|Rickettsiales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_5368693_8	244582.JQAK01000001_gene2132	2.431e-79	268.0	COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria,47FAB@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	ko:K09987	-	-	-	-	ko00000	-	-	-	DUF1013
WLSH2_k127_5368693_13	1267005.KB911255_gene2943	2.077e-47	175.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,3N71K@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	O	Redoxin	MA20_20905	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
WLSH2_k127_5368693_0	985867.AEWF01000002_gene1659	1.274e-226	709.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,47F20@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX2	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH2_k127_5368693_12	985867.AEWF01000003_gene824	5.874e-52	190.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,47FKR@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WLSH2_k127_5368693_7	91604.ID47_10410	1.685e-89	301.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,47F82@766|Rickettsiales	766|Rickettsiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
WLSH2_k127_5368693_4	91604.ID47_00505	1.179e-129	418.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2TTJC@28211|Alphaproteobacteria,47FZM@766|Rickettsiales	766|Rickettsiales	IQ	KR domain	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
WLSH2_k127_5368693_9	985867.AEWF01000004_gene185	1.158e-75	261.0	COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,47FZ4@766|Rickettsiales	766|Rickettsiales	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
WLSH2_k127_5368693_17	244582.JQAK01000001_gene2096	9.121e-26	110.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2UF4N@28211|Alphaproteobacteria,47FUQ@766|Rickettsiales	766|Rickettsiales	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
WLSH2_k127_5368693_14	91604.ID47_00215	1.277e-45	168.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2U9GJ@28211|Alphaproteobacteria,47G81@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
WLSH2_k127_5368693_10	1177928.TH2_20181	1.151e-70	248.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,2TRS7@28211|Alphaproteobacteria,2JQ2M@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
WLSH2_k127_5428954_14	91604.ID47_03600	3.931e-44	164.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TQRE@28211|Alphaproteobacteria,47F4I@766|Rickettsiales	766|Rickettsiales	T	COG0642 Signal transduction histidine kinase	envZ	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WLSH2_k127_5428954_9	985867.AEWF01000007_gene406	1.017e-93	313.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,47FD8@766|Rickettsiales	766|Rickettsiales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ompR	-	-	ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_5428954_3	985867.AEWF01000007_gene405	6.135e-230	719.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,47F0Y@766|Rickettsiales	766|Rickettsiales	C	Dehydrogenase	lpdA-1	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_5428954_7	391600.ABRU01000042_gene2448	5.751e-144	471.0	COG3177@1|root,COG3177@2|Bacteria,1PMMC@1224|Proteobacteria,2U0HK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
WLSH2_k127_5428954_20	244582.JQAK01000001_gene707	3.574e-10	62.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,47F0Y@766|Rickettsiales	766|Rickettsiales	C	Dehydrogenase	lpdA-1	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_5428954_5	595494.Tola_0398	1.078e-162	529.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,1RMCN@1236|Gammaproteobacteria,1Y45R@135624|Aeromonadales	135624|Aeromonadales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WLSH2_k127_5428954_15	244581.IM40_06825	1.164e-42	168.0	COG5599@1|root,COG5599@2|Bacteria,1QU22@1224|Proteobacteria,2TXC7@28211|Alphaproteobacteria,47GTG@766|Rickettsiales	1224|Proteobacteria	T	Inositol hexakisphosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTPlike_phytase
WLSH2_k127_5428954_12	985867.AEWF01000001_gene2061	2.87e-58	205.0	COG3824@1|root,COG3824@2|Bacteria,1N18M@1224|Proteobacteria,2UBUK@28211|Alphaproteobacteria,47G9D@766|Rickettsiales	766|Rickettsiales	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
WLSH2_k127_5428954_17	244582.JQAK01000001_gene975	6.376e-26	117.0	2E53M@1|root,32ZWP@2|Bacteria,1N5H5@1224|Proteobacteria,2UXAH@28211|Alphaproteobacteria,47G7J@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	ko:K11918	-	-	-	-	ko00000,ko02044	-	-	-	-
WLSH2_k127_5428954_19	91604.ID47_11395	2.338e-10	73.0	COG0457@1|root,COG0457@2|Bacteria	91604.ID47_11395|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5428954_1	91604.ID47_02780	8.46e-266	828.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,2TQTR@28211|Alphaproteobacteria,47EU4@766|Rickettsiales	766|Rickettsiales	S	metallo-beta-lactamase	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
WLSH2_k127_5428954_0	91604.ID47_00765	0.0	1019.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2TR9U@28211|Alphaproteobacteria,47EWW@766|Rickettsiales	766|Rickettsiales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WLSH2_k127_5428954_11	227377.CBU_0139	1.89e-83	286.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,1RSY6@1236|Gammaproteobacteria,1JGMC@118969|Legionellales	118969|Legionellales	H	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
WLSH2_k127_5428954_6	985867.AEWF01000004_gene339	4.397e-144	470.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47G2W@766|Rickettsiales	766|Rickettsiales	EGP	Sugar (and other) transporter	-	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1
WLSH2_k127_5428954_16	765952.PUV_13520	2.622e-27	121.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	bioD	-	2.1.1.197,6.3.3.3	ko:K01935,ko:K02169	ko00780,ko01100,map00780,map01100	M00123,M00572,M00573,M00577	R03182,R09543	RC00003,RC00460,RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
WLSH2_k127_5428954_13	244582.JQAK01000001_gene728	3.404e-56	199.0	COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,47FG9@766|Rickettsiales	766|Rickettsiales	L	COG2927 DNA polymerase III, chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
WLSH2_k127_5428954_4	985867.AEWF01000006_gene508	1.732e-196	625.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,47F0A@766|Rickettsiales	766|Rickettsiales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WLSH2_k127_5428954_10	985867.AEWF01000001_gene2250	2.112e-93	321.0	29APY@1|root,2ZXPR@2|Bacteria,1R817@1224|Proteobacteria,2TSBC@28211|Alphaproteobacteria,47FWK@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF1849)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1849
WLSH2_k127_5428954_18	244582.JQAK01000001_gene731	1.914e-11	68.0	COG4321@1|root,COG4321@2|Bacteria,1Q8BU@1224|Proteobacteria,2VEI6@28211|Alphaproteobacteria,47GJM@766|Rickettsiales	766|Rickettsiales	S	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_4
WLSH2_k127_5428954_2	631454.N177_2262	6.363e-248	777.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,1JNN7@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WLSH2_k127_5428954_8	244582.JQAK01000001_gene1105	1.541e-111	365.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,47EZD@766|Rickettsiales	766|Rickettsiales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
WLSH2_k127_5428954_22	91604.ID47_07810	3.853e-05	52.0	2A23R@1|root,30QDZ@2|Bacteria,1Q78T@1224|Proteobacteria,2VDDG@28211|Alphaproteobacteria,47G19@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5579978_0	91604.ID47_08910	8.225e-236	746.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,47GQ6@766|Rickettsiales	766|Rickettsiales	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_5579978_4	323848.Nmul_A0374	4.92e-105	366.0	COG0476@1|root,COG0778@1|root,COG0476@2|Bacteria,COG0778@2|Bacteria,1PDX3@1224|Proteobacteria,2VNSD@28216|Betaproteobacteria,37268@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Nitroreductase family	moeY	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_5579978_7	1283300.ATXB01000001_gene220	1.591e-11	74.0	COG3176@1|root,COG3176@2|Bacteria,1R1UP@1224|Proteobacteria,1T5BM@1236|Gammaproteobacteria,1XGN5@135618|Methylococcales	135618|Methylococcales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
WLSH2_k127_5579978_5	244582.JQAK01000001_gene1602	1.324e-42	160.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,47FHK@766|Rickettsiales	766|Rickettsiales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
WLSH2_k127_5579978_1	91604.ID47_09345	3.722e-177	566.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria,47F2M@766|Rickettsiales	766|Rickettsiales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WLSH2_k127_5579978_2	244582.JQAK01000001_gene915	1.206e-158	515.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,47F65@766|Rickettsiales	766|Rickettsiales	M	COG0739 Membrane proteins related to metalloendopeptidases	nlpD2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH2_k127_5579978_3	91604.ID47_02360	7.438e-110	367.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,47EWZ@766|Rickettsiales	766|Rickettsiales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH2_k127_5579978_9	1506583.JQJY01000001_gene199	0.0001312	47.0	COG2059@1|root,COG2059@2|Bacteria,4NNZ1@976|Bacteroidetes,1HXXV@117743|Flavobacteriia,2NV1C@237|Flavobacterium	976|Bacteroidetes	P	chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WLSH2_k127_5579978_6	658187.LDG_7161	8.512e-32	134.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,1JC54@118969|Legionellales	118969|Legionellales	O	Glutathione peroxidase	btuE	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WLSH2_k127_5579978_8	985867.AEWF01000004_gene346	5.022e-09	69.0	29F8D@1|root,30262@2|Bacteria,1PURK@1224|Proteobacteria,2V6AD@28211|Alphaproteobacteria,47GNX@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_56	1121286.AUMT01000001_gene181	1.636e-12	70.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,1I1CS@117743|Flavobacteriia,3ZPRP@59732|Chryseobacterium	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WLSH2_k127_5583332_28	1230343.CANP01000044_gene3487	4.351e-49	181.0	COG0563@1|root,COG0563@2|Bacteria,1N0HQ@1224|Proteobacteria,1SCDP@1236|Gammaproteobacteria,1JDZS@118969|Legionellales	118969|Legionellales	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_7	985867.AEWF01000001_gene2211	2.175e-191	604.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2U3BS@28211|Alphaproteobacteria,47FZK@766|Rickettsiales	766|Rickettsiales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH2_k127_5583332_17	985867.AEWF01000001_gene2210	1.705e-108	357.0	COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,2U1ES@28211|Alphaproteobacteria,47G1F@766|Rickettsiales	766|Rickettsiales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_5583332_41	985867.AEWF01000001_gene2209	9.531e-36	142.0	COG4706@1|root,COG4706@2|Bacteria,1N00A@1224|Proteobacteria,2UHNU@28211|Alphaproteobacteria,47GBQ@766|Rickettsiales	766|Rickettsiales	I	Dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_11	985867.AEWF01000001_gene2208	3.686e-156	503.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,2U069@28211|Alphaproteobacteria,47G2A@766|Rickettsiales	766|Rickettsiales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH2_k127_5583332_36	91604.ID47_05955	9.679e-40	155.0	2AKR7@1|root,31BI1@2|Bacteria,1Q7CX@1224|Proteobacteria,2VDHW@28211|Alphaproteobacteria,47GB4@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF3261)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3261
WLSH2_k127_5583332_13	1123355.JHYO01000009_gene3109	2.406e-142	463.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,2U2VT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
WLSH2_k127_5583332_6	985867.AEWF01000001_gene2206	5.154e-198	643.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2U3X4@28211|Alphaproteobacteria,47G4E@766|Rickettsiales	766|Rickettsiales	S	exporter	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_34	985867.AEWF01000001_gene2205	4.36e-43	167.0	COG2834@1|root,COG2834@2|Bacteria,1Q1N0@1224|Proteobacteria,2UGT7@28211|Alphaproteobacteria,47GC6@766|Rickettsiales	766|Rickettsiales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_32	985867.AEWF01000001_gene2204	3.759e-44	164.0	COG0824@1|root,COG0824@2|Bacteria,1RH6W@1224|Proteobacteria,2UADR@28211|Alphaproteobacteria,47GBZ@766|Rickettsiales	766|Rickettsiales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	-
WLSH2_k127_5583332_2	985867.AEWF01000001_gene2203	2.495e-245	770.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2TSPJ@28211|Alphaproteobacteria,47G25@766|Rickettsiales	766|Rickettsiales	E	Aromatic amino acid lyase	-	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WLSH2_k127_5583332_4	985867.AEWF01000001_gene2202	1.002e-215	684.0	COG1216@1|root,COG4261@1|root,COG1216@2|Bacteria,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2U2W1@28211|Alphaproteobacteria,47FZU@766|Rickettsiales	766|Rickettsiales	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_5583332_52	674977.VMC_33890	1.958e-16	93.0	COG0764@1|root,COG0764@2|Bacteria,1NAA7@1224|Proteobacteria,1SCQV@1236|Gammaproteobacteria,1XXWN@135623|Vibrionales	135623|Vibrionales	I	3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein)	-	-	-	-	-	-	-	-	-	-	-	-	FabA
WLSH2_k127_5583332_16	985867.AEWF01000001_gene2200	1.047e-110	379.0	COG0318@1|root,COG0318@2|Bacteria,1MXPB@1224|Proteobacteria,2U3YI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
WLSH2_k127_5583332_44	985867.AEWF01000001_gene2199	3.381e-32	133.0	COG4648@1|root,COG4648@2|Bacteria,1N0PK@1224|Proteobacteria,2UFEU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_49	91604.ID47_05910	3.126e-25	108.0	COG0236@1|root,COG0236@2|Bacteria,1N7Q1@1224|Proteobacteria,2UH6B@28211|Alphaproteobacteria,47GEH@766|Rickettsiales	766|Rickettsiales	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH2_k127_5583332_47	985867.AEWF01000001_gene2197	1.024e-28	117.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,2UHI1@28211|Alphaproteobacteria,47GG3@766|Rickettsiales	766|Rickettsiales	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH2_k127_5583332_20	985867.AEWF01000001_gene2196	1.904e-98	329.0	COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,2U88A@28211|Alphaproteobacteria,47FZD@766|Rickettsiales	766|Rickettsiales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WLSH2_k127_5583332_33	985867.AEWF01000001_gene2195	2.383e-43	167.0	2DNSX@1|root,32YZ0@2|Bacteria,1NDSG@1224|Proteobacteria,2UIC0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
WLSH2_k127_5583332_54	985867.AEWF01000001_gene2194	5.161e-16	83.0	2E65Y@1|root,330UM@2|Bacteria,1N8U3@1224|Proteobacteria,2UJ92@28211|Alphaproteobacteria,47GEJ@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_46	985867.AEWF01000001_gene2193	7.592e-30	128.0	2AMT0@1|root,31CPH@2|Bacteria,1Q9EA@1224|Proteobacteria,2VDMN@28211|Alphaproteobacteria,47GHS@766|Rickettsiales	766|Rickettsiales	Q	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH2_k127_5583332_14	985867.AEWF01000004_gene229	4.644e-125	411.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,47F61@766|Rickettsiales	766|Rickettsiales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_21,SMC_N
WLSH2_k127_5583332_45	244582.JQAK01000001_gene1431	2.777e-30	124.0	COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,2UC8X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
WLSH2_k127_5583332_12	244582.JQAK01000001_gene1432	1.336e-142	460.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,47F2C@766|Rickettsiales	766|Rickettsiales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	hflC1	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
WLSH2_k127_5583332_29	1278073.MYSTI_07439	1.822e-47	175.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42TNB@68525|delta/epsilon subdivisions,2WQIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Peptidyl-prolyl cis-trans	fbp	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WLSH2_k127_5583332_30	244582.JQAK01000004_gene300	1.642e-45	169.0	COG0615@1|root,COG0615@2|Bacteria,1QXSR@1224|Proteobacteria,2TXCJ@28211|Alphaproteobacteria,47FJR@766|Rickettsiales	766|Rickettsiales	IM	Cytidylyltransferase-like	tagD	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
WLSH2_k127_5583332_8	985867.AEWF01000003_gene701	3.105e-179	585.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,47F66@766|Rickettsiales	766|Rickettsiales	CO	Thioredoxin-like	dsbD	-	-	ko:K08344	-	-	-	-	ko00000,ko02000	5.A.1.5	-	-	DsbC,DsbD,Thioredoxin_7
WLSH2_k127_5583332_48	1122604.JONR01000015_gene187	1.385e-28	130.0	COG2831@1|root,COG2831@2|Bacteria,1QW38@1224|Proteobacteria,1T2R4@1236|Gammaproteobacteria,1X71G@135614|Xanthomonadales	135614|Xanthomonadales	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
WLSH2_k127_5583332_21	261292.Nit79A3_2571	1.45e-87	299.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,371SS@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WLSH2_k127_5583332_51	1122212.AULO01000007_gene2329	1.864e-19	94.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1XKAM@135619|Oceanospirillales	135619|Oceanospirillales	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
WLSH2_k127_5583332_55	400668.Mmwyl1_2331	2.413e-13	72.0	2E3QA@1|root,32YN8@2|Bacteria,1N98P@1224|Proteobacteria,1SCNQ@1236|Gammaproteobacteria,1XM6K@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
WLSH2_k127_5583332_1	985867.AEWF01000004_gene319	1.933e-303	951.0	COG0642@1|root,COG2205@2|Bacteria,1MVY8@1224|Proteobacteria,2TS5B@28211|Alphaproteobacteria,47FH8@766|Rickettsiales	766|Rickettsiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7
WLSH2_k127_5583332_5	985867.AEWF01000003_gene964	3.616e-208	665.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,47FYY@766|Rickettsiales	766|Rickettsiales	S	Heparinase II III family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_24	91604.ID47_09385	1.269e-81	278.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,47F6A@766|Rickettsiales	766|Rickettsiales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WLSH2_k127_5583332_39	985867.AEWF01000003_gene961	1.209e-36	146.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,47FJF@766|Rickettsiales	766|Rickettsiales	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
WLSH2_k127_5583332_40	244581.IM40_01940	5.763e-36	150.0	2DBXV@1|root,2ZBR7@2|Bacteria,1P0VQ@1224|Proteobacteria,2UUWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_37	244581.IM40_01940	2.482e-38	158.0	2DBXV@1|root,2ZBR7@2|Bacteria,1P0VQ@1224|Proteobacteria,2UUWK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_42	985867.AEWF01000003_gene841	2.277e-35	135.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WLSH2_k127_5583332_19	244582.JQAK01000001_gene1921	3.246e-103	348.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,47F7B@766|Rickettsiales	766|Rickettsiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WLSH2_k127_5583332_15	244582.JQAK01000001_gene1920	3.411e-115	375.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,47G2R@766|Rickettsiales	766|Rickettsiales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WLSH2_k127_5583332_22	91604.ID47_10500	3.78e-87	296.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,47FWM@766|Rickettsiales	766|Rickettsiales	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WLSH2_k127_5583332_35	244582.JQAK01000001_gene1918	2.523e-41	160.0	COG3218@1|root,COG3218@2|Bacteria,1PUEX@1224|Proteobacteria,2V644@28211|Alphaproteobacteria,47GJA@766|Rickettsiales	766|Rickettsiales	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
WLSH2_k127_5583332_59	91604.ID47_10510	3.421e-05	55.0	2AK86@1|root,31AYF@2|Bacteria,1Q6IC@1224|Proteobacteria,2VCP2@28211|Alphaproteobacteria,47GAQ@766|Rickettsiales	766|Rickettsiales	S	A nuclease of the HNH/ENDO VII superfamily with conserved LHH	-	-	-	-	-	-	-	-	-	-	-	-	LHH
WLSH2_k127_5583332_3	91604.ID47_06305	2.059e-224	702.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,47EWV@766|Rickettsiales	766|Rickettsiales	E	Belongs to the glutamine synthetase family	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WLSH2_k127_5583332_26	1444711.CCJF01000005_gene943	1.481e-62	229.0	COG1078@1|root,COG1078@2|Bacteria	2|Bacteria	S	dGTPase activity	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
WLSH2_k127_5583332_25	1522072.IL54_4439	3.105e-80	288.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2TREW@28211|Alphaproteobacteria,2K043@204457|Sphingomonadales	204457|Sphingomonadales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
WLSH2_k127_5583332_0	91604.ID47_11630	5.259e-317	985.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,47EZY@766|Rickettsiales	766|Rickettsiales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
WLSH2_k127_5583332_53	745718.JADT01000044_gene2485	4.465e-16	81.0	COG0454@1|root,COG0456@2|Bacteria,4PMBT@976|Bacteroidetes,1IJR1@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_5583332_43	1121904.ARBP01000018_gene2659	6.896e-34	131.0	COG0454@1|root,COG0456@2|Bacteria,4PMBT@976|Bacteroidetes	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_5583332_10	1408444.JHYC01000007_gene2276	1.227e-162	518.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1JDD4@118969|Legionellales	118969|Legionellales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WLSH2_k127_5583332_9	1122165.AUHS01000037_gene2333	1.108e-170	544.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1JCGD@118969|Legionellales	118969|Legionellales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	-
WLSH2_k127_5583332_38	1444711.CCJF01000005_gene493	9.045e-37	144.0	COG1051@1|root,COG1051@2|Bacteria,2JGFB@204428|Chlamydiae	204428|Chlamydiae	F	NUDIX domain	-	-	-	ko:K12152	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
WLSH2_k127_5583332_27	985867.AEWF01000007_gene399	5.321e-56	200.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2U95Q@28211|Alphaproteobacteria,47FMA@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WLSH2_k127_5583332_31	985867.AEWF01000007_gene398	5.914e-45	166.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2UBSV@28211|Alphaproteobacteria,47FNR@766|Rickettsiales	766|Rickettsiales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WLSH2_k127_5583332_23	985867.AEWF01000003_gene666	8.165e-85	285.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,47FEZ@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
WLSH2_k127_5583332_18	985867.AEWF01000003_gene667	1.225e-103	345.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria,47F5I@766|Rickettsiales	766|Rickettsiales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	p34	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
WLSH2_k127_5583332_57	1111728.ATYS01000016_gene4632	1.579e-05	49.0	2DT0U@1|root,33I6V@2|Bacteria,1NMHR@1224|Proteobacteria,1SGK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_58	1201290.M902_2301	1.638e-05	57.0	COG0642@1|root,COG2205@2|Bacteria	1201290.M902_2301|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5583332_50	680198.SCAB_80291	4.285e-22	109.0	COG0457@1|root,COG0457@2|Bacteria,2GIWN@201174|Actinobacteria	201174|Actinobacteria	D	FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_10,TPR_12
WLSH2_k127_5994067_58	91604.ID47_10725	1.416e-43	177.0	29EJH@1|root,301HH@2|Bacteria,1PSZV@1224|Proteobacteria,2V4ZI@28211|Alphaproteobacteria,47G4S@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5994067_54	985867.AEWF01000003_gene879	2.729e-46	184.0	COG3307@1|root,COG3307@2|Bacteria,1MZYX@1224|Proteobacteria,2UC2T@28211|Alphaproteobacteria,47FSC@766|Rickettsiales	766|Rickettsiales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WLSH2_k127_5994067_42	1238182.C882_2151	1.296e-63	221.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria,2JSDI@204441|Rhodospirillales	204441|Rhodospirillales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
WLSH2_k127_5994067_32	91604.ID47_10710	5.554e-99	335.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,47F7N@766|Rickettsiales	766|Rickettsiales	I	Glycerol-3-phosphate dehydrogenase	gpsA	GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WLSH2_k127_5994067_14	91604.ID47_10705	6.783e-156	497.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2TSF7@28211|Alphaproteobacteria,47ET7@766|Rickettsiales	766|Rickettsiales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WLSH2_k127_5994067_35	91604.ID47_10265	9.683e-76	258.0	COG2823@1|root,COG2823@2|Bacteria,1NJK0@1224|Proteobacteria,2U9XB@28211|Alphaproteobacteria,47FG5@766|Rickettsiales	766|Rickettsiales	S	periplasmic or secreted lipoprotein	osmY	-	-	-	-	-	-	-	-	-	-	-	BON
WLSH2_k127_5994067_65	91604.ID47_10260	1.212e-23	104.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the UPF0102 family	MA20_24645	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
WLSH2_k127_5994067_29	985867.AEWF01000003_gene790	8.194e-104	344.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,47F9A@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WLSH2_k127_5994067_43	91604.ID47_10250	2.628e-63	228.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,47FM5@766|Rickettsiales	766|Rickettsiales	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_6
WLSH2_k127_5994067_31	91604.ID47_10430	2.794e-102	345.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria,47EW4@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WLSH2_k127_5994067_28	244582.JQAK01000001_gene1748	2.373e-112	372.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,47EZ6@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
WLSH2_k127_5994067_57	244582.JQAK01000001_gene1749	1.092e-43	164.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2U987@28211|Alphaproteobacteria,47FGJ@766|Rickettsiales	766|Rickettsiales	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
WLSH2_k127_5994067_6	1088868.CIN_15920	3.794e-212	665.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,2JPVN@204441|Rhodospirillales	204441|Rhodospirillales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WLSH2_k127_5994067_49	1123366.TH3_15724	9.121e-52	189.0	COG0558@1|root,COG0558@2|Bacteria,1RD5Y@1224|Proteobacteria,2U8F4@28211|Alphaproteobacteria,2JSJA@204441|Rhodospirillales	204441|Rhodospirillales	I	COG0558 Phosphatidylglycerophosphate synthase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
WLSH2_k127_5994067_47	1177928.TH2_04020	7.97e-54	197.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,2U6DE@28211|Alphaproteobacteria,2JRU9@204441|Rhodospirillales	204441|Rhodospirillales	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH2_k127_5994067_13	1485545.JQLW01000005_gene1224	2.014e-160	518.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria	1224|Proteobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_5994067_66	1411685.U062_01163	1.858e-19	91.0	COG2128@1|root,COG2128@2|Bacteria,1RC52@1224|Proteobacteria,1S2A0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	ynjA	-	-	-	-	-	-	-	-	-	-	-	CMD
WLSH2_k127_5994067_50	1265313.HRUBRA_00308	2.286e-50	187.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,1T62V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA2	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WLSH2_k127_5994067_63	13035.Dacsa_2599	1.398e-34	140.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
WLSH2_k127_5994067_8	985867.AEWF01000003_gene989	2.624e-203	643.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria,47F2V@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH2_k127_5994067_7	985867.AEWF01000003_gene988	9.687e-209	657.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria,47ETK@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
WLSH2_k127_5994067_55	985867.AEWF01000003_gene748	1.226e-45	171.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,47FJ7@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WLSH2_k127_5994067_21	244582.JQAK01000001_gene1767	1.476e-129	418.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,47EWD@766|Rickettsiales	766|Rickettsiales	D	involved in chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WLSH2_k127_5994067_27	985867.AEWF01000003_gene746	2.289e-112	369.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,47F6R@766|Rickettsiales	766|Rickettsiales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WLSH2_k127_5994067_1	91604.ID47_04540	0.0	1139.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria,47F01@766|Rickettsiales	766|Rickettsiales	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N,SWIM
WLSH2_k127_5994067_26	91604.ID47_00340	8.414e-115	381.0	COG0778@1|root,COG0778@2|Bacteria,1PUI1@1224|Proteobacteria,2U13C@28211|Alphaproteobacteria,47EUV@766|Rickettsiales	28211|Alphaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_5994067_4	91604.ID47_04415	6.445e-226	707.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2TU0C@28211|Alphaproteobacteria,47EZU@766|Rickettsiales	766|Rickettsiales	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
WLSH2_k127_5994067_38	91604.ID47_00600	2.331e-66	231.0	29F2X@1|root,31BF3@2|Bacteria,1Q79S@1224|Proteobacteria,2VDED@28211|Alphaproteobacteria,47G3R@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5994067_61	91604.ID47_00595	7.351e-39	151.0	COG3518@1|root,COG3518@2|Bacteria,1PT5S@1224|Proteobacteria,2V53K@28211|Alphaproteobacteria,47G5T@766|Rickettsiales	766|Rickettsiales	S	Gene 25-like lysozyme	-	-	-	ko:K11897	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
WLSH2_k127_5994067_46	985867.AEWF01000002_gene1574	1.836e-56	215.0	COG3621@1|root,COG3621@2|Bacteria,1RDY7@1224|Proteobacteria,2VGM5@28211|Alphaproteobacteria,47EUB@766|Rickettsiales	766|Rickettsiales	S	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	Patatin
WLSH2_k127_5994067_10	244582.JQAK01000001_gene773	1.242e-178	582.0	COG0515@1|root,COG0515@2|Bacteria,1R4I9@1224|Proteobacteria,2U0GX@28211|Alphaproteobacteria,47FCN@766|Rickettsiales	766|Rickettsiales	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WLSH2_k127_5994067_59	91604.ID47_02640	1.517e-40	159.0	2EA0K@1|root,319E4@2|Bacteria,1Q2GI@1224|Proteobacteria,2V9TZ@28211|Alphaproteobacteria,47G57@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5994067_40	91604.ID47_10165	3.733e-66	229.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria,47FP0@766|Rickettsiales	766|Rickettsiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
WLSH2_k127_5994067_45	91604.ID47_10170	6.793e-57	206.0	COG4395@1|root,COG4395@2|Bacteria,1NCIX@1224|Proteobacteria,2TTDQ@28211|Alphaproteobacteria,47FN2@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
WLSH2_k127_5994067_5	985867.AEWF01000003_gene714	1.582e-224	709.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,47EXT@766|Rickettsiales	766|Rickettsiales	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
WLSH2_k127_5994067_56	985867.AEWF01000003_gene713	6.293e-44	162.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,47FQK@766|Rickettsiales	766|Rickettsiales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
WLSH2_k127_5994067_18	91604.ID47_10175	7.99e-135	438.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,47F8H@766|Rickettsiales	766|Rickettsiales	M	MltA specific insert domain	-	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
WLSH2_k127_5994067_64	985867.AEWF01000003_gene793	6.322e-28	119.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2UCM1@28211|Alphaproteobacteria,47FSV@766|Rickettsiales	766|Rickettsiales	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
WLSH2_k127_5994067_48	91604.ID47_10345	4.504e-52	195.0	COG0583@1|root,COG0583@2|Bacteria,1Q92M@1224|Proteobacteria,2VD82@28211|Alphaproteobacteria,47FHC@766|Rickettsiales	766|Rickettsiales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WLSH2_k127_5994067_0	244582.JQAK01000001_gene943	0.0	1917.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
WLSH2_k127_5994067_25	985867.AEWF01000001_gene2269	7.171e-118	383.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,47F3D@766|Rickettsiales	766|Rickettsiales	S	COG1137 ABC-type (unclassified) transport system, ATPase component	abcT2	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
WLSH2_k127_5994067_62	985867.AEWF01000001_gene2268	1.215e-34	141.0	COG1934@1|root,COG1934@2|Bacteria	2|Bacteria	S	lipopolysaccharide binding	lptA	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iB21_1397.B21_03016,iECBD_1354.ECBD_0542,iECB_1328.ECB_03065,iECD_1391.ECD_03065	OstA
WLSH2_k127_5994067_53	985867.AEWF01000001_gene2267	1.211e-47	178.0	COG5375@1|root,COG5375@2|Bacteria,1Q758@1224|Proteobacteria,2VD9N@28211|Alphaproteobacteria,47FPX@766|Rickettsiales	766|Rickettsiales	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
WLSH2_k127_5994067_24	985867.AEWF01000001_gene2266	1.303e-120	396.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2TU5X@28211|Alphaproteobacteria,47F46@766|Rickettsiales	766|Rickettsiales	M	Belongs to the SIS family. GutQ KpsF subfamily	kpsF	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
WLSH2_k127_5994067_33	985867.AEWF01000007_gene411	1.632e-80	271.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria,47FAI@766|Rickettsiales	766|Rickettsiales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WLSH2_k127_5994067_30	244582.JQAK01000001_gene965	1.576e-103	342.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,47F0G@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH2_k127_5994067_17	985867.AEWF01000007_gene413	3.222e-143	460.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,47EWI@766|Rickettsiales	766|Rickettsiales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WLSH2_k127_5994067_22	985867.AEWF01000007_gene414	3.558e-127	412.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,47ET1@766|Rickettsiales	766|Rickettsiales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WLSH2_k127_5994067_41	985867.AEWF01000004_gene280	5.737e-65	224.0	COG2764@1|root,COG2764@2|Bacteria,1N6GB@1224|Proteobacteria,2VCHU@28211|Alphaproteobacteria,47FNV@766|Rickettsiales	766|Rickettsiales	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WLSH2_k127_5994067_9	244582.JQAK01000001_gene1902	2.487e-192	603.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,47F00@766|Rickettsiales	766|Rickettsiales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WLSH2_k127_5994067_2	985867.AEWF01000003_gene850	0.0	1125.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,47EYK@766|Rickettsiales	766|Rickettsiales	T	histidine kinase response regulator	dhkA	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
WLSH2_k127_5994067_16	91604.ID47_04170	6.848e-146	473.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,47F81@766|Rickettsiales	766|Rickettsiales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
WLSH2_k127_5994067_23	588932.JHOF01000018_gene1216	6.665e-121	396.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2TRRX@28211|Alphaproteobacteria,2KF04@204458|Caulobacterales	204458|Caulobacterales	P	Membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
WLSH2_k127_5994067_11	244582.JQAK01000004_gene134	5.69e-166	541.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2TRVJ@28211|Alphaproteobacteria,47G4C@766|Rickettsiales	766|Rickettsiales	P	K+ potassium transporter	-	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
WLSH2_k127_5994067_44	1121033.AUCF01000003_gene3279	7.646e-63	222.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,2U69V@28211|Alphaproteobacteria,2JRWN@204441|Rhodospirillales	204441|Rhodospirillales	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
WLSH2_k127_5994067_19	985867.AEWF01000001_gene2043	1.37e-134	438.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,47F5G@766|Rickettsiales	766|Rickettsiales	G	COG1472 Beta-glucosidase-related glycosidases	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Glyco_hydro_3
WLSH2_k127_5994067_34	91604.ID47_02055	2.842e-76	261.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2UANG@28211|Alphaproteobacteria,47FCF@766|Rickettsiales	766|Rickettsiales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WLSH2_k127_5994067_12	91604.ID47_10690	1.723e-160	516.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,2UTBP@28211|Alphaproteobacteria,47G1M@766|Rickettsiales	766|Rickettsiales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_5994067_39	91604.ID47_03140	2.599e-66	230.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,47FA3@766|Rickettsiales	766|Rickettsiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WLSH2_k127_5994067_37	91604.ID47_02235	1.387e-71	247.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,47FDT@766|Rickettsiales	766|Rickettsiales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WLSH2_k127_5994067_20	91604.ID47_03780	4.24e-132	427.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,47F6T@766|Rickettsiales	766|Rickettsiales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WLSH2_k127_5994067_36	985867.AEWF01000001_gene2096	3.171e-74	256.0	COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,47FCJ@766|Rickettsiales	766|Rickettsiales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WLSH2_k127_5994067_52	91604.ID47_02760	5.217e-49	185.0	2AKP6@1|root,31BFU@2|Bacteria,1Q7AK@1224|Proteobacteria,2VDF5@28211|Alphaproteobacteria,47G5E@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5994067_60	661367.LLO_0117	2.499e-40	158.0	2C6BU@1|root,32S87@2|Bacteria,1NIFE@1224|Proteobacteria,1SFM9@1236|Gammaproteobacteria,1JFSY@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5994067_15	91604.ID47_08350	2.112e-152	488.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,47EZ9@766|Rickettsiales	766|Rickettsiales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WLSH2_k127_5994067_51	96561.Dole_3165	3.123e-50	187.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WLSH2_k127_5994067_3	244582.JQAK01000001_gene1645	6.857e-308	953.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,47F48@766|Rickettsiales	766|Rickettsiales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WLSH2_k127_5994067_70	981223.AIED01000028_gene365	0.0006651	43.0	2AZUS@1|root,31S44@2|Bacteria,1QPM2@1224|Proteobacteria,1TNBK@1236|Gammaproteobacteria,3NQAU@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5994067_67	91604.ID47_10335	2.886e-14	77.0	2BH5U@1|root,32B6Y@2|Bacteria,1Q1RT@1224|Proteobacteria,2V624@28211|Alphaproteobacteria,47GHW@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6036451_10	985867.AEWF01000006_gene542	3.867e-27	111.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,47FS5@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WLSH2_k127_6036451_5	985867.AEWF01000006_gene543	2.5e-60	209.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,47FE9@766|Rickettsiales	766|Rickettsiales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WLSH2_k127_6036451_1	91604.ID47_00450	3.551e-183	595.0	COG0642@1|root,COG2205@2|Bacteria,1PE4W@1224|Proteobacteria,2V7DJ@28211|Alphaproteobacteria,47G03@766|Rickettsiales	766|Rickettsiales	T	CHASE4 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HATPase_c,HisKA
WLSH2_k127_6036451_2	985867.AEWF01000004_gene215	5.442e-158	507.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,2TS77@28211|Alphaproteobacteria,47FG7@766|Rickettsiales	766|Rickettsiales	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
WLSH2_k127_6036451_9	91604.ID47_00460	4.795e-32	134.0	29F8Z@1|root,3026M@2|Bacteria,1Q77T@1224|Proteobacteria,2VDC9@28211|Alphaproteobacteria,47FXU@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6036451_6	91604.ID47_00465	2.966e-48	173.0	COG1366@1|root,COG1366@2|Bacteria,1NGGT@1224|Proteobacteria,2UHDV@28211|Alphaproteobacteria,47G88@766|Rickettsiales	766|Rickettsiales	T	STAS domain	-	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
WLSH2_k127_6036451_4	91604.ID47_00150	3.644e-77	265.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2TRHN@28211|Alphaproteobacteria,47FDY@766|Rickettsiales	766|Rickettsiales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
WLSH2_k127_6036451_8	91604.ID47_08815	2.163e-41	155.0	COG3761@1|root,COG3761@2|Bacteria,1RHS3@1224|Proteobacteria,2U95G@28211|Alphaproteobacteria,47FSF@766|Rickettsiales	766|Rickettsiales	C	NADH ubiquinone oxidoreductase 17.2 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	NDUFA12
WLSH2_k127_6036451_0	985867.AEWF01000002_gene1420	3.85e-246	773.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,47ET8@766|Rickettsiales	766|Rickettsiales	V	COG1132 ABC-type multidrug transport system, ATPase and permease components	msbA1	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_6036451_3	91604.ID47_09015	3.405e-84	286.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,47FIR@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
WLSH2_k127_6036451_7	985867.AEWF01000002_gene1422	7.191e-45	168.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2UBQA@28211|Alphaproteobacteria,47FPQ@766|Rickettsiales	766|Rickettsiales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WLSH2_k127_6040546_1	985867.AEWF01000002_gene1480	1.097e-21	100.0	COG0355@1|root,COG0355@2|Bacteria,1NIKZ@1224|Proteobacteria,2UKK8@28211|Alphaproteobacteria,47FKQ@766|Rickettsiales	766|Rickettsiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
WLSH2_k127_6040546_0	91604.ID47_10330	3.951e-150	485.0	2BZT9@1|root,2ZEF7@2|Bacteria,1QVXX@1224|Proteobacteria,2TWM6@28211|Alphaproteobacteria,47FJG@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
WLSH2_k127_6108848_3	91604.ID47_06190	8.191e-28	119.0	2BS6C@1|root,32M7F@2|Bacteria,1Q34R@1224|Proteobacteria,2VA5D@28211|Alphaproteobacteria,47G62@766|Rickettsiales	766|Rickettsiales	S	Phage gp6-like head-tail connector protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
WLSH2_k127_6108848_5	985867.AEWF01000001_gene1773	3.431e-05	51.0	2AKTU@1|root,31BKW@2|Bacteria,1Q7FW@1224|Proteobacteria,2VDM4@28211|Alphaproteobacteria,47GGW@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6108848_4	985867.AEWF01000001_gene1774	9.478e-28	117.0	29EWC@1|root,301U3@2|Bacteria,1PTXC@1224|Proteobacteria,2V5R0@28211|Alphaproteobacteria,47GAC@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6108848_2	985867.AEWF01000001_gene1776	3.389e-65	226.0	28SA5@1|root,2ZEMB@2|Bacteria,1N9WW@1224|Proteobacteria,2UIHK@28211|Alphaproteobacteria,47FTN@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6108848_0	91604.ID47_06165	1.763e-133	433.0	COG0697@1|root,COG0697@2|Bacteria,1MX07@1224|Proteobacteria,2TQNT@28211|Alphaproteobacteria,47GQE@766|Rickettsiales	766|Rickettsiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_6108848_1	91604.ID47_06160	1.553e-105	362.0	2EAGC@1|root,334JN@2|Bacteria,1N1US@1224|Proteobacteria,2UEQF@28211|Alphaproteobacteria,47FIH@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6160355_0	985867.AEWF01000004_gene259	4.416e-35	156.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2UF6P@28211|Alphaproteobacteria,47FE1@766|Rickettsiales	766|Rickettsiales	S	Ankyrin repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
WLSH2_k127_6235955_6	985867.AEWF01000002_gene1453	2.962e-116	380.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria,47FY7@766|Rickettsiales	766|Rickettsiales	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WLSH2_k127_6235955_16	1280390.CBQR020000061_gene1216	3.655e-06	61.0	COG0457@1|root,COG0793@1|root,COG0457@2|Bacteria,COG0793@2|Bacteria,1V076@1239|Firmicutes,4HQQT@91061|Bacilli,272BT@186822|Paenibacillaceae	91061|Bacilli	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,TPR_16,TPR_2,TPR_8
WLSH2_k127_6235955_13	985867.AEWF01000002_gene1454	1.212e-24	106.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,47FNB@766|Rickettsiales	766|Rickettsiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WLSH2_k127_6235955_9	244582.JQAK01000004_gene278	1.592e-49	182.0	COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,2U992@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WLSH2_k127_6235955_7	244582.JQAK01000001_gene1549	4.869e-75	255.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,47FBI@766|Rickettsiales	766|Rickettsiales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WLSH2_k127_6235955_0	985867.AEWF01000001_gene1750	0.0	1965.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,47F50@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
WLSH2_k127_6235955_2	78245.Xaut_0549	0.0	1049.0	COG1061@1|root,COG1061@2|Bacteria,1MXFH@1224|Proteobacteria,2TWGC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KL	PFAM type III restriction protein res subunit	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
WLSH2_k127_6235955_14	661367.LLO_2940	2.971e-22	108.0	COG5659@1|root,COG5659@2|Bacteria,1R613@1224|Proteobacteria,1RZI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
WLSH2_k127_6235955_17	661367.LLO_2940	3.317e-05	47.0	COG5659@1|root,COG5659@2|Bacteria,1R613@1224|Proteobacteria,1RZI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
WLSH2_k127_6235955_3	78245.Xaut_0547	1.42e-237	754.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2VB18@28211|Alphaproteobacteria,3F258@335928|Xanthobacteraceae	28211|Alphaproteobacteria	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WLSH2_k127_6235955_8	237368.SCABRO_00086	1.861e-58	212.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	-	-	3.6.4.12	ko:K10742	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_24,PDDEXK_1
WLSH2_k127_6235955_11	1056512.D515_04389	1.21e-35	153.0	COG3540@1|root,COG3540@2|Bacteria,1R6R7@1224|Proteobacteria,1RYX6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3540 Phosphodiesterase alkaline phosphatase D	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
WLSH2_k127_6235955_4	985867.AEWF01000002_gene1640	1.293e-157	501.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria,47EVK@766|Rickettsiales	766|Rickettsiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
WLSH2_k127_6235955_15	985867.AEWF01000007_gene378	6.258e-18	87.0	2A2BK@1|root,30QNI@2|Bacteria,1Q7FK@1224|Proteobacteria,2VDKS@28211|Alphaproteobacteria,47GG1@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF1467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1467
WLSH2_k127_6235955_1	91604.ID47_06025	0.0	1080.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,47EV3@766|Rickettsiales	766|Rickettsiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WLSH2_k127_6235955_10	91604.ID47_06020	1.75e-49	179.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,47FMZ@766|Rickettsiales	766|Rickettsiales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH2_k127_6235955_12	1306406.ASHX01000002_gene5177	1.329e-25	118.0	COG4295@1|root,COG4295@2|Bacteria,2GKXE@201174|Actinobacteria	201174|Actinobacteria	K	Uncharacterized protein conserved in bacteria (DUF2263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2263
WLSH2_k127_6283679_11	985867.AEWF01000001_gene1796	1.528e-86	300.0	2A23R@1|root,314DY@2|Bacteria,1PTZW@1224|Proteobacteria,2V5SW@28211|Alphaproteobacteria,47GBN@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6283679_3	985867.AEWF01000001_gene1845	1.979e-204	649.0	COG1404@1|root,COG1404@2|Bacteria,1PSS6@1224|Proteobacteria,2V4V3@28211|Alphaproteobacteria,47G3G@766|Rickettsiales	766|Rickettsiales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH2_k127_6283679_16	357804.Ping_1006	1.198e-32	134.0	2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,1S78C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3833)	PP2730	-	-	-	-	-	-	-	-	-	-	-	DUF3833
WLSH2_k127_6283679_4	91604.ID47_03895	2.366e-203	656.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,47EWY@766|Rickettsiales	766|Rickettsiales	I	Propionyl-CoA carboxylase alpha	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
WLSH2_k127_6283679_18	985867.AEWF01000007_gene373	2.788e-29	121.0	2ADJZ@1|root,313AE@2|Bacteria,1PS40@1224|Proteobacteria,2V4AZ@28211|Alphaproteobacteria,47GDA@766|Rickettsiales	766|Rickettsiales	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
WLSH2_k127_6283679_15	985867.AEWF01000006_gene579	4.979e-44	186.0	COG1340@1|root,COG1340@2|Bacteria,1Q96X@1224|Proteobacteria,2VDCM@28211|Alphaproteobacteria,47FYQ@766|Rickettsiales	766|Rickettsiales	S	protein secretion by the type IV secretion system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6283679_13	28229.ND2E_0261	6.287e-57	213.0	COG0845@1|root,COG0845@2|Bacteria,1R443@1224|Proteobacteria,1RYSM@1236|Gammaproteobacteria,2Q5MG@267889|Colwelliaceae	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH2_k127_6283679_0	715451.ambt_20910	0.0	1133.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,464D1@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
WLSH2_k127_6283679_20	313612.L8106_01182	2.523e-25	114.0	COG1226@1|root,32Y28@2|Bacteria,1G7VB@1117|Cyanobacteria,1HG2S@1150|Oscillatoriales	1117|Cyanobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
WLSH2_k127_6283679_5	1268635.Loa_00219	2.626e-193	613.0	COG1373@1|root,COG1373@2|Bacteria,1MWDX@1224|Proteobacteria,1RYD6@1236|Gammaproteobacteria,1JFUU@118969|Legionellales	118969|Legionellales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_6283679_10	985867.AEWF01000001_gene2166	1.46e-94	316.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2TTZV@28211|Alphaproteobacteria,47FDQ@766|Rickettsiales	766|Rickettsiales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
WLSH2_k127_6283679_8	91604.ID47_07905	6.863e-123	406.0	COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,2TQW3@28211|Alphaproteobacteria,47EYY@766|Rickettsiales	766|Rickettsiales	I	Enoyl-CoA hydratase/isomerase	-	-	3.1.2.4	ko:K05605	ko00280,ko00410,ko00640,ko01100,ko01200,map00280,map00410,map00640,map01100,map01200	M00013	R03158,R05064	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
WLSH2_k127_6283679_17	91604.ID47_07865	3.709e-32	128.0	COG2919@1|root,COG2919@2|Bacteria,1Q75Y@1224|Proteobacteria,2VDAB@28211|Alphaproteobacteria,47FSI@766|Rickettsiales	766|Rickettsiales	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
WLSH2_k127_6283679_19	5762.XP_002671624.1	1.101e-27	120.0	COG0790@1|root,KOG1550@2759|Eukaryota	2759|Eukaryota	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
WLSH2_k127_6283679_9	1336208.JADY01000002_gene204	1.666e-111	377.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,2JQ1V@204441|Rhodospirillales	204441|Rhodospirillales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
WLSH2_k127_6283679_2	91604.ID47_06395	4.05e-248	773.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,47EU0@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WLSH2_k127_6283679_1	91604.ID47_06400	1.239e-289	901.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,47EU1@766|Rickettsiales	766|Rickettsiales	C	NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADH5_C,Proton_antipo_M,Proton_antipo_N
WLSH2_k127_6283679_12	91604.ID47_09080	8.859e-77	262.0	COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,2U7CB@28211|Alphaproteobacteria,47F7H@766|Rickettsiales	766|Rickettsiales	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_N_3
WLSH2_k127_6283679_7	244582.JQAK01000001_gene679	3.242e-146	476.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,47F3Z@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH2_k127_6283679_14	91604.ID47_00770	1.205e-49	183.0	COG0790@1|root,COG0790@2|Bacteria,1Q79M@1224|Proteobacteria,2VDEA@28211|Alphaproteobacteria,47G3J@766|Rickettsiales	766|Rickettsiales	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
WLSH2_k127_6283679_6	985867.AEWF01000004_gene228	2.508e-166	542.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2TT8A@28211|Alphaproteobacteria,47F5P@766|Rickettsiales	766|Rickettsiales	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
WLSH2_k127_6294733_0	985867.AEWF01000001_gene1809	2.328e-90	299.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,47ET6@766|Rickettsiales	766|Rickettsiales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_6385984_4	575586.HMPREF0016_00598	7.308e-36	139.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SAT7@1236|Gammaproteobacteria,3NNGV@468|Moraxellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_6385984_2	91604.ID47_09205	1.463e-152	496.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,2VF0H@28211|Alphaproteobacteria,47F1M@766|Rickettsiales	766|Rickettsiales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_6385984_1	91604.ID47_09200	4.195e-171	550.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,2TS48@28211|Alphaproteobacteria,47FBK@766|Rickettsiales	766|Rickettsiales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_6385984_3	78898.MVEG_01283T0	1.438e-45	184.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38KU9@33154|Opisthokonta,3NXW6@4751|Fungi	4751|Fungi	AT	Mortierella verticillata NRRL 6337	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
WLSH2_k127_6385984_6	135651.CBN09593	7.17e-15	87.0	KOG1908@1|root,KOG1908@2759|Eukaryota,38WGW@33154|Opisthokonta,3BFV5@33208|Metazoa,3CWDU@33213|Bilateria,40AWX@6231|Nematoda,1KYJV@119089|Chromadorea,410JT@6236|Rhabditida	33208|Metazoa	A	Leucine Rich repeat	PPP1R37	GO:0008150,GO:0009892,GO:0010563,GO:0010921,GO:0010923,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0035303,GO:0035305,GO:0043086,GO:0044092,GO:0045936,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051174,GO:0051336,GO:0051346,GO:0065007,GO:0065009	-	ko:K17576	-	-	-	-	ko00000,ko01009	-	-	-	LRR_6
WLSH2_k127_6385984_0	985867.AEWF01000004_gene176	0.0	1099.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,47F1Q@766|Rickettsiales	766|Rickettsiales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WLSH2_k127_6434029_1	244582.JQAK01000001_gene2031	1.299e-40	156.0	COG2905@1|root,COG2905@2|Bacteria,1QXSK@1224|Proteobacteria,2TXCG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_6434029_0	91604.ID47_10755	0.0	1292.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,47EUQ@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WLSH2_k127_6434029_2	86106.I862_01195	1.169e-35	148.0	COG0265@1|root,COG0265@2|Bacteria,1RBDX@1224|Proteobacteria,2U6E8@28211|Alphaproteobacteria,47F6D@766|Rickettsiales	766|Rickettsiales	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_6559064_46	439375.Oant_0133	3.793e-06	57.0	COG3637@1|root,COG3637@2|Bacteria,1NJWW@1224|Proteobacteria,2UD8G@28211|Alphaproteobacteria,1J3QB@118882|Brucellaceae	28211|Alphaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
WLSH2_k127_6559064_6	985867.AEWF01000004_gene138	8.389e-285	885.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,47EYD@766|Rickettsiales	766|Rickettsiales	M	Cell division protein FtsI penicillin-binding protein 2	pbpA1	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WLSH2_k127_6559064_32	91604.ID47_11765	9.814e-46	170.0	2BZN9@1|root,301IM@2|Bacteria,1PT3C@1224|Proteobacteria,2V51V@28211|Alphaproteobacteria,47G5D@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	-
WLSH2_k127_6559064_40	1485545.JQLW01000009_gene86	6.062e-17	83.0	COG1708@1|root,COG1708@2|Bacteria,1N7SN@1224|Proteobacteria	1224|Proteobacteria	S	PFAM DNA polymerase, beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH2_k127_6559064_33	452471.Aasi_0740	2.167e-39	150.0	COG1373@1|root,COG1373@2|Bacteria,4NEMX@976|Bacteroidetes,47MKR@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_6559064_26	452659.RrIowa_1398	2.411e-89	301.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria,47FW5@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_6559064_42	266779.Meso_0132	1.1e-16	82.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2TU59@28211|Alphaproteobacteria,43J7Z@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	COG0842 ABC-type multidrug transport system, permease component	ybhR	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH2_k127_6559064_22	1122164.JHWF01000023_gene434	5.922e-96	326.0	COG0845@1|root,COG0845@2|Bacteria,1N4HU@1224|Proteobacteria,1S8NY@1236|Gammaproteobacteria,1JDB5@118969|Legionellales	118969|Legionellales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
WLSH2_k127_6559064_7	86106.I862_05540	9.41e-221	721.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,47EX4@766|Rickettsiales	766|Rickettsiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18989	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718,M00720	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.30	-	-	ACR_tran
WLSH2_k127_6559064_19	765952.PUV_01660	1.694e-106	359.0	COG0842@1|root,COG0842@2|Bacteria,2JFF8@204428|Chlamydiae	204428|Chlamydiae	V	ABC-2 family transporter protein	ybhR	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH2_k127_6559064_17	1437425.CSEC_2285	8.564e-114	378.0	COG0842@1|root,COG0842@2|Bacteria,2JFXH@204428|Chlamydiae	204428|Chlamydiae	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH2_k127_6559064_8	1028307.EAE_14555	9.787e-209	663.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,3X1T9@547|Enterobacter	1236|Gammaproteobacteria	V	ABC transporter	ybhF	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_6559064_21	690850.Desaf_0397	2.126e-96	327.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MGB8@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
WLSH2_k127_6559064_0	91604.ID47_07980	0.0	1384.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,47EYC@766|Rickettsiales	766|Rickettsiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WLSH2_k127_6559064_20	985867.AEWF01000007_gene466	4.128e-101	339.0	COG0760@1|root,COG0760@2|Bacteria,1PSH9@1224|Proteobacteria,2V4P5@28211|Alphaproteobacteria,47G1H@766|Rickettsiales	766|Rickettsiales	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
WLSH2_k127_6559064_37	91604.ID47_04105	1.228e-25	114.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2UGK6@28211|Alphaproteobacteria,47FKW@766|Rickettsiales	766|Rickettsiales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
WLSH2_k127_6559064_13	91604.ID47_06595	3.074e-121	404.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,47F5Z@766|Rickettsiales	766|Rickettsiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WLSH2_k127_6559064_29	91604.ID47_06600	1.424e-54	197.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria,47FH6@766|Rickettsiales	766|Rickettsiales	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	yhbH	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
WLSH2_k127_6559064_27	985867.AEWF01000004_gene244	1.669e-60	211.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,47FBY@766|Rickettsiales	766|Rickettsiales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
WLSH2_k127_6559064_9	244582.JQAK01000004_gene347	5.709e-153	493.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria,47FAU@766|Rickettsiales	766|Rickettsiales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_6559064_24	244582.JQAK01000004_gene217	3.44e-91	321.0	COG3774@1|root,COG3774@2|Bacteria,1PEQW@1224|Proteobacteria,2V41W@28211|Alphaproteobacteria,47FWJ@766|Rickettsiales	766|Rickettsiales	M	Glycosyltransferase sugar-binding region containing DXD motif	-	-	-	-	-	-	-	-	-	-	-	-	Gly_transf_sug
WLSH2_k127_6559064_25	244582.JQAK01000004_gene216	1.077e-90	317.0	COG0500@1|root,COG3475@1|root,COG0500@2|Bacteria,COG3475@2|Bacteria,1NEZ9@1224|Proteobacteria,2UF4R@28211|Alphaproteobacteria,47GS9@766|Rickettsiales	766|Rickettsiales	MQ	LicD family	-	-	-	-	-	-	-	-	-	-	-	-	LicD
WLSH2_k127_6559064_4	91604.ID47_01840	0.0	1069.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,47F38@766|Rickettsiales	766|Rickettsiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WLSH2_k127_6559064_30	91604.ID47_06030	1.717e-54	194.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2U93J@28211|Alphaproteobacteria,47G63@766|Rickettsiales	766|Rickettsiales	I	Thioesterase superfamily	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
WLSH2_k127_6559064_3	985867.AEWF01000001_gene2220	0.0	1160.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,47F0I@766|Rickettsiales	766|Rickettsiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH2_k127_6559064_14	91604.ID47_03395	1.239e-120	409.0	COG4805@1|root,COG4805@2|Bacteria,1PIM6@1224|Proteobacteria,2UAH8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WLSH2_k127_6559064_34	697282.Mettu_2502	5.575e-37	143.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SA4A@1236|Gammaproteobacteria,1XFUA@135618|Methylococcales	135618|Methylococcales	L	Protein of unknown function (DUF559)	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
WLSH2_k127_6559064_11	985867.AEWF01000007_gene366	5.3e-136	445.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47G3Y@766|Rickettsiales	766|Rickettsiales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6559064_23	91604.ID47_01995	1.164e-92	319.0	COG2200@1|root,COG2200@2|Bacteria,1R5R6@1224|Proteobacteria,2TU0I@28211|Alphaproteobacteria,47FRP@766|Rickettsiales	766|Rickettsiales	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
WLSH2_k127_6559064_12	91604.ID47_07970	2.288e-133	433.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,47FV3@766|Rickettsiales	766|Rickettsiales	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WLSH2_k127_6559064_31	985867.AEWF01000002_gene1337	1.218e-47	175.0	2AKK5@1|root,31BCB@2|Bacteria,1Q76Y@1224|Proteobacteria,2VDBC@28211|Alphaproteobacteria,47FVK@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF2750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2750
WLSH2_k127_6559064_2	985867.AEWF01000004_gene292	0.0	1224.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,47EZJ@766|Rickettsiales	766|Rickettsiales	L	This protein is involved in the repair of mismatches in DNA	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WLSH2_k127_6559064_41	985867.AEWF01000006_gene535	8.308e-17	82.0	COG1476@1|root,COG1476@2|Bacteria,1P625@1224|Proteobacteria,2V643@28211|Alphaproteobacteria,47GJ9@766|Rickettsiales	766|Rickettsiales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6559064_36	985867.AEWF01000006_gene536	6.955e-29	119.0	COG3550@1|root,COG3550@2|Bacteria	2|Bacteria	S	kinase activity	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
WLSH2_k127_6559064_16	985867.AEWF01000006_gene537	5.489e-114	375.0	COG3550@1|root,COG3550@2|Bacteria,1RHBA@1224|Proteobacteria,2V4K6@28211|Alphaproteobacteria,47FZZ@766|Rickettsiales	766|Rickettsiales	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
WLSH2_k127_6559064_1	91604.ID47_08090	0.0	1264.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,47F1J@766|Rickettsiales	766|Rickettsiales	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
WLSH2_k127_6559064_10	985867.AEWF01000001_gene2134	4.178e-147	472.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria,47EXD@766|Rickettsiales	766|Rickettsiales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
WLSH2_k127_6559064_15	244582.JQAK01000001_gene2102	4.236e-116	383.0	COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2TV9J@28211|Alphaproteobacteria,47FYS@766|Rickettsiales	766|Rickettsiales	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
WLSH2_k127_6559064_18	985867.AEWF01000004_gene225	5.28e-107	355.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2TTI4@28211|Alphaproteobacteria,47FHG@766|Rickettsiales	766|Rickettsiales	S	P-loop ATPase protein family	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
WLSH2_k127_6559064_39	985867.AEWF01000004_gene224	3.036e-19	94.0	COG2847@1|root,COG2847@2|Bacteria,1N3BG@1224|Proteobacteria,2UM57@28211|Alphaproteobacteria,47FNQ@766|Rickettsiales	766|Rickettsiales	S	Pfam:DUF461	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
WLSH2_k127_6559064_28	658187.LDG_7107	1.202e-57	201.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,1S6NH@1236|Gammaproteobacteria,1JER2@118969|Legionellales	118969|Legionellales	J	Putative tRNA binding domain	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	tRNA_bind
WLSH2_k127_6559064_48	97139.C824_01001	0.0001513	55.0	COG4115@1|root,COG4115@2|Bacteria,1VEN0@1239|Firmicutes,24MYT@186801|Clostridia,36T2H@31979|Clostridiaceae	186801|Clostridia	S	YoeB-like toxin of bacterial type II toxin-antitoxin system	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
WLSH2_k127_6559064_38	1278311.AUAL01000040_gene713	4.233e-22	113.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
WLSH2_k127_6559064_5	91604.ID47_03125	2.082e-289	899.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,47F1D@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WLSH2_k127_6559064_47	285535.JOEY01000035_gene3715	6.361e-06	48.0	COG0477@1|root,COG0477@2|Bacteria,2H6BY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_6759875_4	91604.ID47_06385	3.95e-83	285.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,47FFK@766|Rickettsiales	766|Rickettsiales	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,BPL_LplA_LipB_2
WLSH2_k127_6759875_1	985867.AEWF01000001_gene2133	4.825e-179	567.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,47G4Q@766|Rickettsiales	766|Rickettsiales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_6759875_8	98439.AJLL01000089_gene3806	1.526e-51	191.0	COG1285@1|root,COG1285@2|Bacteria,1G354@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	iJN678.mgtC	MgtC
WLSH2_k127_6759875_11	857293.CAAU_0084	6.423e-08	65.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,36HXX@31979|Clostridiaceae	186801|Clostridia	M	Subtilase family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
WLSH2_k127_6759875_10	1173024.KI912148_gene2701	8.888e-12	78.0	COG1404@1|root,COG1404@2|Bacteria,1G04D@1117|Cyanobacteria,1JKHR@1189|Stigonemataceae	1117|Cyanobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_S8
WLSH2_k127_6759875_7	244582.JQAK01000004_gene127	1.032e-58	212.0	COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,2TVD9@28211|Alphaproteobacteria,47GBU@766|Rickettsiales	766|Rickettsiales	I	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH2_k127_6759875_6	244582.JQAK01000004_gene128	2.492e-60	214.0	COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,2TVD9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Phospholipid N-methyltransferase	pmtA	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,RrnaAD
WLSH2_k127_6759875_2	91604.ID47_10695	1.859e-143	458.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,2TS4S@28211|Alphaproteobacteria,47F1K@766|Rickettsiales	766|Rickettsiales	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
WLSH2_k127_6759875_5	911045.PSE_p0252	3.799e-61	220.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,2U2KK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	lgtF	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_6759875_0	91604.ID47_06075	5.47e-251	780.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,47F3K@766|Rickettsiales	766|Rickettsiales	C	isocitrate	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WLSH2_k127_6759875_3	91604.ID47_05150	5.607e-129	423.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria,47FW5@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_6759875_9	1408444.JHYC01000009_gene1744	9.033e-46	172.0	COG1309@1|root,COG1309@2|Bacteria,1N7QG@1224|Proteobacteria	1224|Proteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
WLSH2_k127_6783626_1	1519464.HY22_00560	1.133e-12	69.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Reprolysin_5
WLSH2_k127_6783626_0	1121472.AQWN01000001_gene283	5.925e-18	94.0	COG1349@1|root,COG1349@2|Bacteria,1VC1B@1239|Firmicutes,24P9E@186801|Clostridia,265X6@186807|Peptococcaceae	186801|Clostridia	GK	Protein of unknown function (DUF1670)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1670
WLSH2_k127_6794406_4	244581.IM40_00080	4.238e-69	245.0	COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,1MZV9@1224|Proteobacteria,2TWJW@28211|Alphaproteobacteria,47F32@766|Rickettsiales	766|Rickettsiales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,Hexapep
WLSH2_k127_6794406_0	91604.ID47_04575	0.0	1400.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,47EVS@766|Rickettsiales	766|Rickettsiales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WLSH2_k127_6794406_3	1122164.JHWF01000026_gene352	4.955e-91	313.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,1RNVR@1236|Gammaproteobacteria,1JDZ9@118969|Legionellales	118969|Legionellales	P	TrkA-N domain	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
WLSH2_k127_6794406_8	91604.ID47_11530	2.101e-20	93.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,47F0W@766|Rickettsiales	766|Rickettsiales	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
WLSH2_k127_6794406_2	1034943.BN1094_02737	2.179e-144	478.0	2EW55@1|root,33PI9@2|Bacteria,1QC2T@1224|Proteobacteria,1T7QT@1236|Gammaproteobacteria,1JFQ2@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6794406_1	91604.ID47_11530	1.699e-274	875.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,47F0W@766|Rickettsiales	766|Rickettsiales	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
WLSH2_k127_6794406_6	985867.AEWF01000003_gene956	1.44e-56	204.0	COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	-	-	-	-	-	-	-	-	-	LolA
WLSH2_k127_6794406_5	91604.ID47_07955	9.058e-64	230.0	COG5001@1|root,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria,2V7DK@28211|Alphaproteobacteria,47FZB@766|Rickettsiales	766|Rickettsiales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
WLSH2_k127_6794406_10	1245471.PCA10_46080	6.257e-09	67.0	COG1361@1|root,COG2202@1|root,COG2931@1|root,COG3188@1|root,COG3210@1|root,COG1361@2|Bacteria,COG2202@2|Bacteria,COG2931@2|Bacteria,COG3188@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,1RX6F@1236|Gammaproteobacteria,1YJEZ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	MNQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
WLSH2_k127_7013934_2	1121396.KB892957_gene3215	2.772e-30	120.0	COG1452@1|root,COG1452@2|Bacteria,1QW3G@1224|Proteobacteria,43CZ5@68525|delta/epsilon subdivisions,2X87D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7013934_0	177437.HRM2_24360	1.055e-54	199.0	2BWMW@1|root,32QZS@2|Bacteria,1NG2J@1224|Proteobacteria,42VWY@68525|delta/epsilon subdivisions,2WSFB@28221|Deltaproteobacteria,2MKVZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
WLSH2_k127_7013934_1	1318628.MARLIPOL_16284	1.309e-40	155.0	2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,1SUQW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7021370_16	244582.JQAK01000001_gene812	1.24e-35	136.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria,47FKP@766|Rickettsiales	766|Rickettsiales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WLSH2_k127_7021370_13	244582.JQAK01000001_gene811	3.427e-48	173.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,47FK1@766|Rickettsiales	766|Rickettsiales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WLSH2_k127_7021370_18	985867.AEWF01000001_gene1975	1.43e-29	120.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2UBX6@28211|Alphaproteobacteria,47FQQ@766|Rickettsiales	766|Rickettsiales	N	Bacterial export proteins, family 3	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
WLSH2_k127_7021370_10	91604.ID47_02525	8.82e-76	261.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2TTHN@28211|Alphaproteobacteria,47FI5@766|Rickettsiales	766|Rickettsiales	NU	Bacterial export proteins, family 1	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
WLSH2_k127_7021370_15	91604.ID47_10995	4.828e-37	143.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,47FM0@766|Rickettsiales	766|Rickettsiales	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
WLSH2_k127_7021370_7	985867.AEWF01000003_gene940	4.399e-85	288.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,47F8T@766|Rickettsiales	766|Rickettsiales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
WLSH2_k127_7021370_22	985867.AEWF01000003_gene939	1.018e-11	74.0	2AJUU@1|root,31AHH@2|Bacteria,1Q5NF@1224|Proteobacteria,2VBZM@28211|Alphaproteobacteria,47G6V@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7021370_17	1444711.CCJF01000004_gene2206	2.042e-34	137.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_7021370_6	91604.ID47_10565	6.551e-87	292.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2TRXJ@28211|Alphaproteobacteria,47FD4@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WLSH2_k127_7021370_9	91604.ID47_01770	1.992e-79	267.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2TTCK@28211|Alphaproteobacteria,47FT9@766|Rickettsiales	766|Rickettsiales	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
WLSH2_k127_7021370_23	909943.HIMB100_00007770	2.222e-09	69.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	CP_0488	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
WLSH2_k127_7021370_24	765952.PUV_05530	3.47e-08	58.0	2EFVT@1|root,339N0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7021370_4	1144888.CM001467_gene301	1.113e-132	434.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_7021370_3	985867.AEWF01000001_gene1859	9.498e-138	452.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,47F88@766|Rickettsiales	766|Rickettsiales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WLSH2_k127_7021370_0	91604.ID47_05835	0.0	1124.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,47EXX@766|Rickettsiales	766|Rickettsiales	C	Malic enzyme	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
WLSH2_k127_7021370_8	244582.JQAK01000001_gene1041	7.712e-83	284.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WLSH2_k127_7021370_11	985867.AEWF01000003_gene657	7.4e-66	231.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria,47FD3@766|Rickettsiales	766|Rickettsiales	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WLSH2_k127_7021370_1	244582.JQAK01000001_gene1068	5.022e-145	467.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,47EUG@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WLSH2_k127_7021370_5	91604.ID47_06850	1.144e-105	351.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,47FET@766|Rickettsiales	766|Rickettsiales	J	ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WLSH2_k127_7021370_2	452471.Aasi_1916	2.461e-140	464.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,47J9E@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WLSH2_k127_7021370_21	697282.Mettu_4296	4.193e-19	99.0	29X56@1|root,30IU6@2|Bacteria,1NGEN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7021370_19	1399147.P618_200555	3.653e-29	129.0	COG0454@1|root,COG0454@2|Bacteria,1N23J@1224|Proteobacteria,2UC2A@28211|Alphaproteobacteria,47FIX@766|Rickettsiales	766|Rickettsiales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_7021370_12	1122165.AUHS01000031_gene465	1.574e-55	198.0	COG0454@1|root,COG0456@2|Bacteria,1PGJZ@1224|Proteobacteria,1TC1C@1236|Gammaproteobacteria,1JGD6@118969|Legionellales	118969|Legionellales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_7021370_14	472759.Nhal_1671	2.246e-44	167.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1WYZZ@135613|Chromatiales	135613|Chromatiales	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WLSH2_k127_7021370_20	1288963.ADIS_4387	1.252e-26	115.0	COG4948@1|root,COG4948@2|Bacteria,4NEPP@976|Bacteroidetes,47M8J@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_7054256_5	244582.JQAK01000001_gene2116	1.209e-89	299.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,47ET6@766|Rickettsiales	766|Rickettsiales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_7054256_4	985867.AEWF01000001_gene1808	4.359e-160	514.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,47EV0@766|Rickettsiales	766|Rickettsiales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WLSH2_k127_7054256_0	91604.ID47_01810	0.0	1350.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,47F2F@766|Rickettsiales	766|Rickettsiales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
WLSH2_k127_7054256_2	985867.AEWF01000001_gene1805	4.144e-164	519.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria,47EV4@766|Rickettsiales	766|Rickettsiales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
WLSH2_k127_7054256_1	91604.ID47_01795	7.685e-187	591.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,47EYN@766|Rickettsiales	766|Rickettsiales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
WLSH2_k127_7054256_3	91604.ID47_01790	4.41e-164	520.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,47EYA@766|Rickettsiales	766|Rickettsiales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
WLSH2_k127_7054256_7	91604.ID47_01785	8.701e-84	284.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2TTWP@28211|Alphaproteobacteria,47FHM@766|Rickettsiales	766|Rickettsiales	S	hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
WLSH2_k127_7054256_8	29495.EA26_13360	1.482e-78	274.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1Q7PK@1224|Proteobacteria,1RSF0@1236|Gammaproteobacteria,1Y326@135623|Vibrionales	135623|Vibrionales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_33
WLSH2_k127_7054256_10	91604.ID47_04705	5.39e-07	59.0	COG0810@1|root,COG0810@2|Bacteria,1Q7F7@1224|Proteobacteria,2VDKE@28211|Alphaproteobacteria,47GFA@766|Rickettsiales	766|Rickettsiales	U	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WLSH2_k127_7054256_6	91604.ID47_04700	1.357e-89	320.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TT3G@28211|Alphaproteobacteria,47FVS@766|Rickettsiales	766|Rickettsiales	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
WLSH2_k127_7332077_1	985867.AEWF01000001_gene1798	1.504e-45	183.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria,1R6J6@1224|Proteobacteria,2U3C8@28211|Alphaproteobacteria,47FXB@766|Rickettsiales	766|Rickettsiales	MT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
WLSH2_k127_7332077_0	91604.ID47_06205	1.581e-215	674.0	COG4695@1|root,COG4695@2|Bacteria,1MUP5@1224|Proteobacteria,2TT33@28211|Alphaproteobacteria,47EUP@766|Rickettsiales	766|Rickettsiales	S	Phage portal protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
WLSH2_k127_7365017_14	985867.AEWF01000001_gene1947	5.688e-140	449.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2TUB5@28211|Alphaproteobacteria,47F5M@766|Rickettsiales	766|Rickettsiales	S	Rhodanese Homology Domain	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
WLSH2_k127_7365017_27	985867.AEWF01000001_gene1767	1.042e-34	136.0	COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,47FMW@766|Rickettsiales	766|Rickettsiales	C	Succinate dehydrogenase, cytochrome b556 subunit	sdhC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WLSH2_k127_7365017_29	244582.JQAK01000001_gene1231	6.502e-31	126.0	COG2142@1|root,COG2142@2|Bacteria,1Q3QW@1224|Proteobacteria,2VAE5@28211|Alphaproteobacteria,47FT2@766|Rickettsiales	766|Rickettsiales	C	Succinate dehydrogenase hydrophobic	sdhD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WLSH2_k127_7365017_12	985867.AEWF01000006_gene587	9.14e-143	458.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,47F6W@766|Rickettsiales	766|Rickettsiales	L	Exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WLSH2_k127_7365017_5	91604.ID47_11705	1.998e-251	788.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,47EW3@766|Rickettsiales	766|Rickettsiales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WLSH2_k127_7365017_26	985867.AEWF01000006_gene567	1.959e-35	137.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VD95@28211|Alphaproteobacteria,47FN5@766|Rickettsiales	766|Rickettsiales	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH2_k127_7365017_11	244582.JQAK01000004_gene351	6.444e-171	541.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,47EV5@766|Rickettsiales	766|Rickettsiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WLSH2_k127_7365017_10	244582.JQAK01000004_gene350	3.192e-183	578.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,47F43@766|Rickettsiales	766|Rickettsiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WLSH2_k127_7365017_13	331869.BAL199_25719	1.398e-141	460.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,4BPRH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	1.2.4.1,2.3.1.12	ko:K00162,ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R02569,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WLSH2_k127_7365017_3	91604.ID47_09185	7.546e-277	861.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,47EWE@766|Rickettsiales	766|Rickettsiales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
WLSH2_k127_7365017_19	1144319.PMI16_00922	1.165e-84	284.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2VK49@28216|Betaproteobacteria,474CR@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red,Flavodoxin_5
WLSH2_k127_7365017_7	244582.JQAK01000001_gene1693	1.135e-191	606.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47F3Y@766|Rickettsiales	766|Rickettsiales	EGP	Major facilitator	proP6	-	-	ko:K03762	-	-	-	-	ko00000,ko02000	2.A.1.6.4	-	-	MFS_1,Sugar_tr
WLSH2_k127_7365017_6	1230343.CANP01000048_gene3680	2.566e-222	706.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1S04I@1236|Gammaproteobacteria,1JDPW@118969|Legionellales	118969|Legionellales	P	E1-E2 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
WLSH2_k127_7365017_16	91604.ID47_00280	9.302e-120	399.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria,47G4J@766|Rickettsiales	766|Rickettsiales	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_7365017_0	331869.BAL199_10862	0.0	1092.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,4BPMR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Bacterial NAD-glutamate dehydrogenase	gdhB	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
WLSH2_k127_7365017_33	985867.AEWF01000002_gene1553	1.48e-16	83.0	COG1551@1|root,COG1551@2|Bacteria,1Q20H@1224|Proteobacteria,2UHK1@28211|Alphaproteobacteria,47FUA@766|Rickettsiales	766|Rickettsiales	T	Global regulator protein family	-	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
WLSH2_k127_7365017_30	91604.ID47_08840	3.836e-25	108.0	2C7H7@1|root,301WJ@2|Bacteria,1PU39@1224|Proteobacteria,2V5VD@28211|Alphaproteobacteria,47GDB@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
WLSH2_k127_7365017_24	985867.AEWF01000002_gene1555	5.932e-46	169.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2U94I@28211|Alphaproteobacteria,47FQE@766|Rickettsiales	766|Rickettsiales	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WLSH2_k127_7365017_32	985867.AEWF01000002_gene1556	1.6e-22	99.0	2AJU2@1|root,31AGK@2|Bacteria,1QFZ4@1224|Proteobacteria,2V5WU@28211|Alphaproteobacteria,47GE6@766|Rickettsiales	766|Rickettsiales	S	Flagellar hook-basal body complex protein FliE	-	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
WLSH2_k127_7365017_22	985867.AEWF01000004_gene136	8.135e-61	221.0	COG1792@1|root,COG1792@2|Bacteria	2|Bacteria	M	regulation of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WLSH2_k127_7365017_8	985867.AEWF01000004_gene135	1.155e-185	586.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,47EYF@766|Rickettsiales	766|Rickettsiales	D	Rod shape-determining protein (MreB)	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WLSH2_k127_7365017_21	985867.AEWF01000004_gene241	8.558e-73	254.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2U7CZ@28211|Alphaproteobacteria,47FDR@766|Rickettsiales	766|Rickettsiales	M	COG2853 Surface lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
WLSH2_k127_7365017_25	985867.AEWF01000002_gene1385	1.391e-45	169.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria,47FQD@766|Rickettsiales	766|Rickettsiales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
WLSH2_k127_7365017_2	244582.JQAK01000001_gene1690	2.994e-281	889.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,47EW9@766|Rickettsiales	766|Rickettsiales	D	Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity)	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH2_k127_7365017_17	985867.AEWF01000002_gene1476	7.584e-101	332.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,47F4C@766|Rickettsiales	766|Rickettsiales	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WLSH2_k127_7365017_15	985867.AEWF01000002_gene1477	1.703e-126	422.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,47F6I@766|Rickettsiales	766|Rickettsiales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WLSH2_k127_7365017_35	1035839.AFNK01000085_gene486	2.294e-09	58.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7365017_9	244582.JQAK01000004_gene123	1.397e-185	590.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,2U6FF@28211|Alphaproteobacteria,47FIT@766|Rickettsiales	766|Rickettsiales	G	Sugar phosphate permease	uhpC	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
WLSH2_k127_7365017_18	244582.JQAK01000004_gene122	1.185e-93	311.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,47FCV@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
WLSH2_k127_7365017_34	1265505.ATUG01000002_gene1327	7.282e-10	71.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,42KZ4@68525|delta/epsilon subdivisions,2WKT2@28221|Deltaproteobacteria,2MJ8K@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
WLSH2_k127_7365017_1	985867.AEWF01000004_gene67	1.454e-294	921.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,47ETD@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
WLSH2_k127_7365017_20	153721.MYP_205	2.431e-79	268.0	COG1225@1|root,COG1225@2|Bacteria,4NMET@976|Bacteroidetes,47PI0@768503|Cytophagia	976|Bacteroidetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_7365017_31	985867.AEWF01000003_gene762	3.252e-24	105.0	2AKS5@1|root,31BJ3@2|Bacteria,1Q7DY@1224|Proteobacteria,2VDIY@28211|Alphaproteobacteria,47GCM@766|Rickettsiales	766|Rickettsiales	S	Frataxin-like domain	-	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
WLSH2_k127_7365017_4	91604.ID47_10090	6.78e-259	810.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,47EVM@766|Rickettsiales	766|Rickettsiales	V	Part of an ABC transporter complex. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation (By similarity)	msbA2	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_7365017_28	91604.ID47_10830	4.44e-33	136.0	2AJH8@1|root,31A3T@2|Bacteria,1Q4VH@1224|Proteobacteria,2VBA5@28211|Alphaproteobacteria,47G5J@766|Rickettsiales	766|Rickettsiales	S	OmpA-like transmembrane domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
WLSH2_k127_7365017_23	91604.ID47_10830	1.835e-51	189.0	2AJH8@1|root,31A3T@2|Bacteria,1Q4VH@1224|Proteobacteria,2VBA5@28211|Alphaproteobacteria,47G5J@766|Rickettsiales	766|Rickettsiales	S	OmpA-like transmembrane domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
WLSH2_k127_737038_1	985867.AEWF01000006_gene583	1.407e-50	186.0	COG0454@1|root,COG2320@1|root,COG0456@2|Bacteria,COG2320@2|Bacteria,1RD0I@1224|Proteobacteria,2UIWW@28211|Alphaproteobacteria,47FC9@766|Rickettsiales	766|Rickettsiales	K	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10,GrpB
WLSH2_k127_737038_2	391616.OA238_c29190	8.645e-26	113.0	2ECEJ@1|root,336CU@2|Bacteria,1N0XT@1224|Proteobacteria,2UUDS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_737038_0	86106.I862_06950	4.585e-77	266.0	COG3173@1|root,COG3173@2|Bacteria,1MYZZ@1224|Proteobacteria,2V9VW@28211|Alphaproteobacteria,47G65@766|Rickettsiales	766|Rickettsiales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_7445762_4	1038922.PflQ2_5432	0.0002259	52.0	COG1404@1|root,COG1404@2|Bacteria,1QYUS@1224|Proteobacteria,1T3VT@1236|Gammaproteobacteria,1YSFZ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH2_k127_7445762_0	91604.ID47_11525	7.4e-323	1023.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,47ETW@766|Rickettsiales	766|Rickettsiales	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	recB	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WLSH2_k127_7445762_1	118005.AWNK01000011_gene117	9.556e-143	465.0	COG3328@1|root,COG3328@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
WLSH2_k127_7445762_3	91604.ID47_09000	7.619e-59	214.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	com1	-	5.3.4.1	ko:K03805,ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DSBA,Thioredoxin_4
WLSH2_k127_7445762_2	91604.ID47_10325	4.397e-59	212.0	2AE0H@1|root,313T4@2|Bacteria,1PSYX@1224|Proteobacteria,2V4Z0@28211|Alphaproteobacteria,47G0Y@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7464295_5	244581.IM40_03505	2.649e-55	206.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Pilus assembly protein	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
WLSH2_k127_7464295_0	450851.PHZ_c3000	1.426e-125	419.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,2KFEJ@204458|Caulobacterales	204458|Caulobacterales	U	secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WLSH2_k127_7464295_3	244581.IM40_03495	8.549e-98	333.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Pilus assembly protein	cpaE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CBP_BcsQ,CbiA,ParA
WLSH2_k127_7464295_9	91604.ID47_09765	1.577e-18	94.0	COG5461@1|root,COG5461@2|Bacteria,1QPEH@1224|Proteobacteria,2V65S@28211|Alphaproteobacteria,47GK9@766|Rickettsiales	766|Rickettsiales	N	Pilus biogenesis CpaD protein (pilus_cpaD)	-	-	-	ko:K02281	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Pilus_CpaD
WLSH2_k127_7464295_1	91604.ID47_09760	4.123e-120	406.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,47GF1@766|Rickettsiales	766|Rickettsiales	U	Bacterial type II and III secretion system protein	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Secretin
WLSH2_k127_7464295_7	91604.ID47_09755	1.033e-43	169.0	COG3745@1|root,COG3745@2|Bacteria,1Q7CW@1224|Proteobacteria,2VDHU@28211|Alphaproteobacteria,47GAZ@766|Rickettsiales	766|Rickettsiales	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC
WLSH2_k127_7464295_4	91604.ID47_09745	1.762e-55	203.0	COG5010@1|root,COG5010@2|Bacteria,1MVUP@1224|Proteobacteria,2V9HV@28211|Alphaproteobacteria,47FRI@766|Rickettsiales	766|Rickettsiales	U	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
WLSH2_k127_7464295_6	985867.AEWF01000001_gene1733	2.195e-49	183.0	COG2913@1|root,COG2913@2|Bacteria,1N8M2@1224|Proteobacteria	1224|Proteobacteria	J	SmpA / OmlA family	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
WLSH2_k127_7464295_2	1408444.JHYC01000007_gene2301	2.059e-119	392.0	COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,1RN80@1236|Gammaproteobacteria,1JC8Y@118969|Legionellales	118969|Legionellales	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox
WLSH2_k127_7506261_2	244582.JQAK01000004_gene276	6.571e-215	681.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2TR6J@28211|Alphaproteobacteria,47F49@766|Rickettsiales	766|Rickettsiales	NU	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
WLSH2_k127_7506261_5	1123355.JHYO01000011_gene1495	1.661e-112	372.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2TRIV@28211|Alphaproteobacteria,36XEV@31993|Methylocystaceae	28211|Alphaproteobacteria	N	FliG middle domain	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
WLSH2_k127_7506261_11	985867.AEWF01000002_gene1644	2.621e-32	134.0	COG1317@1|root,COG1317@2|Bacteria,1Q782@1224|Proteobacteria,2VDCK@28211|Alphaproteobacteria,47FYP@766|Rickettsiales	766|Rickettsiales	NU	bacterial-type flagellum organization	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	-
WLSH2_k127_7506261_10	985867.AEWF01000002_gene1645	2.893e-37	145.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2UC6U@28211|Alphaproteobacteria,47FPZ@766|Rickettsiales	766|Rickettsiales	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
WLSH2_k127_7506261_3	91604.ID47_06870	2.579e-189	600.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,47F3B@766|Rickettsiales	766|Rickettsiales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH2_k127_7506261_1	91604.ID47_06865	7.012e-312	968.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2TQUR@28211|Alphaproteobacteria,47EYS@766|Rickettsiales	766|Rickettsiales	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
WLSH2_k127_7506261_15	1286632.P278_28390	3.954e-06	59.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1HXFD@117743|Flavobacteriia	976|Bacteroidetes	O	Belongs to the peptidase S8 family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH2_k127_7506261_9	91604.ID47_08715	1.298e-50	181.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,47FJQ@766|Rickettsiales	766|Rickettsiales	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH2_k127_7506261_6	91604.ID47_11280	3.062e-107	353.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2TT93@28211|Alphaproteobacteria,47F06@766|Rickettsiales	766|Rickettsiales	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
WLSH2_k127_7506261_14	985867.AEWF01000003_gene993	1.472e-08	59.0	2AESK@1|root,314PD@2|Bacteria,1PUG9@1224|Proteobacteria,2V650@28211|Alphaproteobacteria,47GJS@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7506261_12	91604.ID47_11290	7.008e-26	110.0	2A574@1|root,30TW5@2|Bacteria,1Q9AM@1224|Proteobacteria,2VDHR@28211|Alphaproteobacteria,47GAU@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7506261_4	985867.AEWF01000003_gene995	1.892e-178	571.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,2TW8J@28211|Alphaproteobacteria,47GTP@766|Rickettsiales	766|Rickettsiales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WLSH2_k127_7506261_8	244582.JQAK01000001_gene2032	3.106e-62	221.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,47FCU@766|Rickettsiales	766|Rickettsiales	J	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WLSH2_k127_7506261_7	985867.AEWF01000003_gene885	7.718e-92	313.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,47FCG@766|Rickettsiales	766|Rickettsiales	E	AFG1-like ATPase	n2B	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
WLSH2_k127_7506261_0	985867.AEWF01000002_gene1349	0.0	1362.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,47EWP@766|Rickettsiales	766|Rickettsiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity)	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH2_k127_7628928_4	985867.AEWF01000011_gene1225	2.315e-55	199.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2UCXW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
WLSH2_k127_7628928_5	469595.CSAG_04126	3.928e-29	121.0	COG0589@1|root,COG0589@2|Bacteria,1N9BR@1224|Proteobacteria,1SFNQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_7628928_3	1278073.MYSTI_01038	2.898e-65	242.0	COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,42UCF@68525|delta/epsilon subdivisions,2WREI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
WLSH2_k127_7628928_2	246197.MXAN_3432	1.264e-176	563.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42PNF@68525|delta/epsilon subdivisions,2WKN3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WLSH2_k127_7628928_6	91604.ID47_10825	5.956e-27	115.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,47FKH@766|Rickettsiales	766|Rickettsiales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
WLSH2_k127_7628928_0	1121022.ABENE_22735	1.245e-233	743.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2KFFV@204458|Caulobacterales	204458|Caulobacterales	P	Haloacid dehalogenase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
WLSH2_k127_7628928_1	91604.ID47_05710	1.722e-185	617.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,1MWRF@1224|Proteobacteria,2U9VQ@28211|Alphaproteobacteria,47F2N@766|Rickettsiales	766|Rickettsiales	Q	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_5,GerE,NB-ARC,TPR_12,TPR_2,TPR_7,TPR_8
WLSH2_k127_7628928_8	1211817.CCAT010000062_gene3907	0.0005777	51.0	COG2247@1|root,COG3227@1|root,COG4886@1|root,COG2247@2|Bacteria,COG3227@2|Bacteria,COG4886@2|Bacteria,1VS6B@1239|Firmicutes	1239|Firmicutes	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,DUF5011
WLSH2_k127_7628928_7	1305737.JAFX01000001_gene2360	4.809e-21	106.0	COG3491@1|root,COG3491@2|Bacteria,4NED5@976|Bacteroidetes,47JDX@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
WLSH2_k127_7629747_11	91604.ID47_09100	1.449e-24	106.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	CP_0257	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
WLSH2_k127_7629747_7	1034943.BN1094_02754	6.033e-46	168.0	COG3070@1|root,COG3070@2|Bacteria,1N0ND@1224|Proteobacteria,1SE8F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Regulator of competence-specific genes	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
WLSH2_k127_7629747_9	1444712.BN1013_00103	1.049e-32	141.0	COG0510@1|root,COG0510@2|Bacteria,2JH7I@204428|Chlamydiae	204428|Chlamydiae	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7629747_1	244582.JQAK01000001_gene1279	3.663e-154	490.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,2TRY4@28211|Alphaproteobacteria,47FY5@766|Rickettsiales	766|Rickettsiales	KL	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,HTH_18
WLSH2_k127_7629747_0	91604.ID47_02075	4.364e-190	601.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,47F37@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WLSH2_k127_7629747_8	91604.ID47_02085	1.095e-45	173.0	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2TUNI@28211|Alphaproteobacteria,47FJA@766|Rickettsiales	766|Rickettsiales	D	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
WLSH2_k127_7629747_12	1522072.IL54_0171	2.196e-05	47.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2K0IX@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WLSH2_k127_7629747_5	91604.ID47_02085	9.236e-90	304.0	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2TUNI@28211|Alphaproteobacteria,47FJA@766|Rickettsiales	766|Rickettsiales	D	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
WLSH2_k127_7629747_10	244582.JQAK01000001_gene1445	3.547e-31	125.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,47FKT@766|Rickettsiales	766|Rickettsiales	U	The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF- YajC-YidC subcomplex facilitates these functions	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
WLSH2_k127_7629747_2	1123355.JHYO01000005_gene796	6.457e-146	479.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,36XME@31993|Methylocystaceae	28211|Alphaproteobacteria	U	Protein export membrane protein	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH2_k127_7629747_6	244581.IM40_07595	4.096e-83	286.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,47F5C@766|Rickettsiales	766|Rickettsiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH2_k127_7629747_4	985867.AEWF01000001_gene1716	9.225e-128	421.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,47EUC@766|Rickettsiales	766|Rickettsiales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WLSH2_k127_7629747_3	244582.JQAK01000001_gene961	6.738e-139	445.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria,47ET2@766|Rickettsiales	766|Rickettsiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH2_k127_7630023_1	1238182.C882_4251	2.912e-18	100.0	COG2982@1|root,COG2982@2|Bacteria,1QY0F@1224|Proteobacteria,2TY3Y@28211|Alphaproteobacteria,2JYZF@204441|Rhodospirillales	204441|Rhodospirillales	M	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
WLSH2_k127_7630023_2	1238182.C882_4252	3.581e-13	74.0	2E371@1|root,32Y6T@2|Bacteria,1N8D8@1224|Proteobacteria,2UGA5@28211|Alphaproteobacteria,2JUT3@204441|Rhodospirillales	204441|Rhodospirillales	S	YnbE-like lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
WLSH2_k127_7630023_3	392500.Swoo_1912	4.286e-05	49.0	COG3784@1|root,COG3784@2|Bacteria,1N6R1@1224|Proteobacteria,1SC8V@1236|Gammaproteobacteria,2QCJX@267890|Shewanellaceae	1236|Gammaproteobacteria	S	conserved protein UCP025560	ydbL	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
WLSH2_k127_7630023_0	985867.AEWF01000001_gene2032	5.527e-120	393.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,47EXI@766|Rickettsiales	766|Rickettsiales	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
WLSH2_k127_7643771_0	985867.AEWF01000004_gene265	1.457e-191	602.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,47EU2@766|Rickettsiales	766|Rickettsiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WLSH2_k127_7643771_2	91604.ID47_10230	5.2e-07	57.0	2AKUJ@1|root,31BMN@2|Bacteria,1Q7GN@1224|Proteobacteria,2VDMX@28211|Alphaproteobacteria,47GI9@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7643771_1	985867.AEWF01000003_gene788	2.893e-120	395.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,47ETZ@766|Rickettsiales	766|Rickettsiales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH2_k127_7650838_1	909663.KI867150_gene337	1.601e-51	192.0	COG0823@1|root,COG0823@2|Bacteria,1Q2D4@1224|Proteobacteria,437ZF@68525|delta/epsilon subdivisions,2X39G@28221|Deltaproteobacteria,2MSI3@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7900556_3	91604.ID47_08855	6.455e-15	79.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,47F0Q@766|Rickettsiales	766|Rickettsiales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WLSH2_k127_7900556_0	1121013.P873_04835	2.691e-64	229.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,1S22P@1236|Gammaproteobacteria,1X3J4@135614|Xanthomonadales	135614|Xanthomonadales	M	Dolichol-phosphate mannosyltransferase	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WLSH2_k127_7900556_2	78898.MVEG_02525T0	1.037e-34	155.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38KU9@33154|Opisthokonta,3NXW6@4751|Fungi	4751|Fungi	AT	Mortierella verticillata NRRL 6337	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
WLSH2_k127_7900556_1	985867.AEWF01000002_gene1400	8.51e-59	233.0	2AKVW@1|root,31BP3@2|Bacteria,1Q7IP@1224|Proteobacteria,2VDPZ@28211|Alphaproteobacteria,47GN7@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8031947_0	985867.AEWF01000007_gene407	4.699e-120	392.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TQRE@28211|Alphaproteobacteria,47F4I@766|Rickettsiales	766|Rickettsiales	T	COG0642 Signal transduction histidine kinase	envZ	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WLSH2_k127_8087545_4	91604.ID47_04045	1.933e-105	346.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,47F9V@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
WLSH2_k127_8087545_1	985867.AEWF01000004_gene357	2.71e-148	477.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,47G4M@766|Rickettsiales	766|Rickettsiales	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
WLSH2_k127_8087545_10	7739.XP_002595932.1	4.401e-16	92.0	COG4886@1|root,KOG0619@2759|Eukaryota	2759|Eukaryota	U	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8
WLSH2_k127_8087545_2	589865.DaAHT2_2586	2.798e-126	415.0	COG3550@1|root,COG3550@2|Bacteria,1RHBA@1224|Proteobacteria,42VDG@68525|delta/epsilon subdivisions,2X5H7@28221|Deltaproteobacteria,2MKX7@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
WLSH2_k127_8087545_9	589865.DaAHT2_2585	2.615e-16	82.0	COG3620@1|root,COG3620@2|Bacteria,1MYVA@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
WLSH2_k127_8087545_0	91604.ID47_10740	2.822e-201	634.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2U059@28211|Alphaproteobacteria,47G0M@766|Rickettsiales	766|Rickettsiales	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
WLSH2_k127_8087545_5	91604.ID47_10745	3.094e-75	254.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2U5EA@28211|Alphaproteobacteria,47FE5@766|Rickettsiales	766|Rickettsiales	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH2_k127_8087545_6	91604.ID47_10345	3.636e-62	226.0	COG0583@1|root,COG0583@2|Bacteria,1Q92M@1224|Proteobacteria,2VD82@28211|Alphaproteobacteria,47FHC@766|Rickettsiales	766|Rickettsiales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WLSH2_k127_8087545_3	91604.ID47_04485	5.263e-119	386.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,47F63@766|Rickettsiales	766|Rickettsiales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
WLSH2_k127_8087545_7	985867.AEWF01000004_gene274	2.419e-60	212.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,47FCY@766|Rickettsiales	766|Rickettsiales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WLSH2_k127_8087545_8	985867.AEWF01000004_gene275	4.977e-59	210.0	COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,47FHU@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
WLSH2_k127_8113190_15	1397284.AYMN01000008_gene2000	8.455e-07	51.0	COG3415@1|root,COG3415@2|Bacteria,1P1T3@1224|Proteobacteria,1SSIX@1236|Gammaproteobacteria,405EN@613|Serratia	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29
WLSH2_k127_8113190_13	985867.AEWF01000003_gene895	1.004e-33	139.0	2AJH8@1|root,31A3T@2|Bacteria,1Q4VH@1224|Proteobacteria,2VBA5@28211|Alphaproteobacteria,47G5J@766|Rickettsiales	766|Rickettsiales	S	OmpA-like transmembrane domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
WLSH2_k127_8113190_5	452659.RrIowa_1249	3.354e-113	380.0	COG0477@1|root,COG0477@2|Bacteria,1RG0P@1224|Proteobacteria,2U7W3@28211|Alphaproteobacteria,47F8M@766|Rickettsiales	766|Rickettsiales	EGP	COG0477 Permeases of the major facilitator superfamily	proP4	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_8113190_3	1379701.JPJC01000076_gene2640	8.4e-159	512.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JZV4@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH2_k127_8113190_8	91604.ID47_02340	5.359e-108	357.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,47F1U@766|Rickettsiales	766|Rickettsiales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
WLSH2_k127_8113190_2	244582.JQAK01000001_gene1398	2.002e-184	585.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria,47EVX@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WLSH2_k127_8113190_6	985867.AEWF01000007_gene403	5.221e-110	367.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2TS4G@28211|Alphaproteobacteria,47F7D@766|Rickettsiales	766|Rickettsiales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
WLSH2_k127_8113190_9	91604.ID47_10730	2.965e-70	243.0	2CN5Z@1|root,32SGB@2|Bacteria,1N1FB@1224|Proteobacteria,2UBV1@28211|Alphaproteobacteria,47G2X@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF2948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2948
WLSH2_k127_8113190_1	985867.AEWF01000003_gene951	2.063e-195	616.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,47EX5@766|Rickettsiales	766|Rickettsiales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WLSH2_k127_8113190_12	985867.AEWF01000003_gene952	2.087e-39	152.0	COG3034@1|root,COG3034@2|Bacteria	2|Bacteria	M	peptidoglycan biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WLSH2_k127_8113190_7	244582.JQAK01000001_gene1674	7.551e-110	357.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2TSDM@28211|Alphaproteobacteria,47F3H@766|Rickettsiales	766|Rickettsiales	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
WLSH2_k127_8113190_4	91604.ID47_02410	5.956e-119	385.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,47F7F@766|Rickettsiales	766|Rickettsiales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WLSH2_k127_8113190_10	985867.AEWF01000001_gene2000	3.256e-57	202.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,47FHD@766|Rickettsiales	766|Rickettsiales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WLSH2_k127_8113190_0	91604.ID47_08685	1.892e-205	646.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,47F3V@766|Rickettsiales	766|Rickettsiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WLSH2_k127_8113190_11	1304866.K413DRAFT_0395	1.254e-40	153.0	COG3911@1|root,COG3911@2|Bacteria,1USSP@1239|Firmicutes,24ZQP@186801|Clostridia,36R5U@31979|Clostridiaceae	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
WLSH2_k127_8234420_13	985867.AEWF01000003_gene834	1.234e-19	100.0	2A53A@1|root,30TRS@2|Bacteria,1Q97K@1224|Proteobacteria,2VDDD@28211|Alphaproteobacteria,47G13@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8234420_4	1090319.KE386571_gene3012	7.038e-113	376.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2TSIP@28211|Alphaproteobacteria,2K0VH@204457|Sphingomonadales	204457|Sphingomonadales	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
WLSH2_k127_8234420_17	1036674.A28LD_1128	4.439e-05	54.0	COG3012@1|root,COG3012@2|Bacteria,1R46G@1224|Proteobacteria,1RMGM@1236|Gammaproteobacteria,2QGS1@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
WLSH2_k127_8234420_5	985867.AEWF01000007_gene477	3.437e-110	360.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,47EY4@766|Rickettsiales	766|Rickettsiales	IQ	dehydrogenases with different specificities (related to short-chain alcohol)	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_8234420_3	244582.JQAK01000001_gene817	2.35e-121	397.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,47EZI@766|Rickettsiales	766|Rickettsiales	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WLSH2_k127_8234420_15	225849.swp_4876	2.739e-14	81.0	COG0671@1|root,COG0671@2|Bacteria,1N3TP@1224|Proteobacteria,1SADV@1236|Gammaproteobacteria,2QARH@267890|Shewanellaceae	1236|Gammaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WLSH2_k127_8234420_12	313606.M23134_02958	3.642e-22	109.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8
WLSH2_k127_8234420_10	985867.AEWF01000006_gene615	5.095e-55	203.0	COG1434@1|root,COG1434@2|Bacteria,1RHMV@1224|Proteobacteria,2U957@28211|Alphaproteobacteria,47FK9@766|Rickettsiales	766|Rickettsiales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WLSH2_k127_8234420_0	244581.IM40_09620	6.156e-150	482.0	COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,2UPMJ@28211|Alphaproteobacteria,47FWQ@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
WLSH2_k127_8234420_14	400682.PAC_15721258	3.307e-17	94.0	COG4870@1|root,2S8PN@2759|Eukaryota,39QU5@33154|Opisthokonta	33154|Opisthokonta	O	Belongs to the peptidase C1 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
WLSH2_k127_8234420_11	985867.AEWF01000001_gene1813	5.793e-28	117.0	2BT51@1|root,32N9R@2|Bacteria,1Q3NZ@1224|Proteobacteria,2VC4V@28211|Alphaproteobacteria,47GCD@766|Rickettsiales	766|Rickettsiales	S	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
WLSH2_k127_8234420_7	985867.AEWF01000001_gene1812	6.957e-84	304.0	COG1345@1|root,COG1345@2|Bacteria,1Q77G@1224|Proteobacteria,2VDBZ@28211|Alphaproteobacteria,47FX7@766|Rickettsiales	766|Rickettsiales	N	Flagellar hook-associated protein 2 N-terminus	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
WLSH2_k127_8234420_2	91604.ID47_02150	3.734e-139	457.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2TT8X@28211|Alphaproteobacteria,47G1V@766|Rickettsiales	28211|Alphaproteobacteria	N	Bacterial flagellin N-terminal helical region	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WLSH2_k127_8234420_1	91604.ID47_02475	1.093e-141	471.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,47FIG@766|Rickettsiales	766|Rickettsiales	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
WLSH2_k127_8234420_8	244582.JQAK01000004_gene155	1.073e-73	257.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,47F6P@766|Rickettsiales	766|Rickettsiales	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WLSH2_k127_8234420_16	91604.ID47_09040	6.122e-11	74.0	2AKV0@1|root,31BN5@2|Bacteria,1Q7H7@1224|Proteobacteria,2VDNM@28211|Alphaproteobacteria,47GJ6@766|Rickettsiales	91604.ID47_09040|-	S	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8234420_9	765952.PUV_13550	1.119e-61	219.0	COG0132@1|root,COG0132@2|Bacteria,2JGXM@204428|Chlamydiae	204428|Chlamydiae	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
WLSH2_k127_8234420_18	1430440.MGMSRv2_0928	0.0002031	44.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2U5AJ@28211|Alphaproteobacteria,2JSUQ@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	2.1.1.197,6.3.3.3	ko:K01935,ko:K02169	ko00780,ko01100,map00780,map01100	M00123,M00572,M00573,M00577	R03182,R09543	RC00003,RC00460,RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Methyltransf_12,Methyltransf_23,Methyltransf_25
WLSH2_k127_8234420_6	91604.ID47_09130	6.169e-110	359.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria,47EXE@766|Rickettsiales	766|Rickettsiales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
WLSH2_k127_8403132_6	1208323.B30_11280	3.363e-18	101.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria	28211|Alphaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	pkcI	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WLSH2_k127_8403132_9	65489.OBART10G03980.1	0.0001439	56.0	2D2C0@1|root,2SMBI@2759|Eukaryota,37YJG@33090|Viridiplantae,3GNXU@35493|Streptophyta,3KPSA@4447|Liliopsida,3I7PF@38820|Poales	35493|Streptophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_17
WLSH2_k127_8403132_5	526224.Bmur_0622	1.138e-21	112.0	COG0666@1|root,COG0666@2|Bacteria,2J5FX@203691|Spirochaetes	203691|Spirochaetes	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
WLSH2_k127_8403132_3	91604.ID47_03595	5.04e-34	136.0	COG5490@1|root,COG5490@2|Bacteria,1Q76F@1224|Proteobacteria,2VDAV@28211|Alphaproteobacteria,47FTU@766|Rickettsiales	766|Rickettsiales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
WLSH2_k127_8403132_2	985867.AEWF01000001_gene1847	6.986e-104	346.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2UC0Y@28211|Alphaproteobacteria,47G9R@766|Rickettsiales	766|Rickettsiales	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8403132_1	985867.AEWF01000001_gene2062	1.188e-209	655.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria,47G22@766|Rickettsiales	766|Rickettsiales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_8403132_10	765952.PUV_16110	0.000601	43.0	COG1672@1|root,COG1672@2|Bacteria,2JGKE@204428|Chlamydiae	204428|Chlamydiae	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,HTH_5
WLSH2_k127_8403132_8	4113.PGSC0003DMT400020472	5.482e-10	72.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,3G9ZF@35493|Streptophyta,44RPV@71274|asterids	35493|Streptophyta	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LRR_6,LRR_8
WLSH2_k127_8403132_0	91604.ID47_06480	0.0	1386.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,47EW6@766|Rickettsiales	766|Rickettsiales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WLSH2_k127_8403132_4	1492737.FEM08_08850	6.093e-26	110.0	COG4680@1|root,COG4680@2|Bacteria,4NQ54@976|Bacteroidetes,1I2RY@117743|Flavobacteriia,2NWYJ@237|Flavobacterium	976|Bacteroidetes	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
WLSH2_k127_8403132_7	228410.NE1587	4.185e-11	66.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,2VRK1@28216|Betaproteobacteria,37351@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
WLSH2_k127_8479513_14	189426.PODO_09655	9.41e-12	74.0	COG4859@1|root,COG4859@2|Bacteria,1UYUT@1239|Firmicutes,4HXMB@91061|Bacilli,2755H@186822|Paenibacillaceae	91061|Bacilli	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
WLSH2_k127_8479513_0	91604.ID47_00375	4.561e-228	718.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,47EZ7@766|Rickettsiales	766|Rickettsiales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
WLSH2_k127_8479513_9	91604.ID47_11205	8.925e-41	158.0	2AKKR@1|root,31BD4@2|Bacteria,1Q77N@1224|Proteobacteria,2VDC4@28211|Alphaproteobacteria,47FXM@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8479513_13	272624.lpg1742	1.189e-12	70.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria,1JFBK@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8479513_3	985867.AEWF01000003_gene904	3.264e-122	398.0	COG0568@1|root,COG0568@2|Bacteria,1MUXA@1224|Proteobacteria,2TUED@28211|Alphaproteobacteria,47G2V@766|Rickettsiales	766|Rickettsiales	K	Sigma-70, region 4	-	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
WLSH2_k127_8479513_2	91604.ID47_11315	1.669e-133	430.0	COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,47F75@766|Rickettsiales	766|Rickettsiales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MipZ
WLSH2_k127_8479513_12	985867.AEWF01000003_gene998	3.116e-15	85.0	2AF2E@1|root,3150Y@2|Bacteria,1PUZD@1224|Proteobacteria,2V4YQ@28211|Alphaproteobacteria,47G78@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8479513_4	985867.AEWF01000004_gene131	8.287e-118	413.0	COG0457@1|root,COG0457@2|Bacteria,1N09H@1224|Proteobacteria,2TSKT@28211|Alphaproteobacteria,47FKB@766|Rickettsiales	766|Rickettsiales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8479513_8	985867.AEWF01000004_gene130	8.268e-64	237.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,47FA1@766|Rickettsiales	766|Rickettsiales	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
WLSH2_k127_8479513_15	985867.AEWF01000003_gene977	1.476e-09	61.0	COG3024@1|root,COG3024@2|Bacteria,1PU08@1224|Proteobacteria,2VD3R@28211|Alphaproteobacteria,47GP4@766|Rickettsiales	766|Rickettsiales	S	DNA gyrase inhibitor YacG	-	-	-	-	-	-	-	-	-	-	-	-	YacG
WLSH2_k127_8479513_11	985867.AEWF01000003_gene978	4.699e-33	142.0	COG1530@1|root,COG1530@2|Bacteria,1PUBQ@1224|Proteobacteria,2V4P8@28211|Alphaproteobacteria,47G1I@766|Rickettsiales	766|Rickettsiales	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
WLSH2_k127_8479513_10	244582.JQAK01000001_gene1753	4.084e-35	134.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,47FN6@766|Rickettsiales	766|Rickettsiales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WLSH2_k127_8479513_5	985867.AEWF01000001_gene1692	5.708e-99	331.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,47EWJ@766|Rickettsiales	766|Rickettsiales	C	Cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
WLSH2_k127_8479513_1	91604.ID47_08375	9.768e-227	707.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,47EXV@766|Rickettsiales	766|Rickettsiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
WLSH2_k127_8479513_7	91604.ID47_08370	1.024e-77	264.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria,47F5K@766|Rickettsiales	766|Rickettsiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
WLSH2_k127_8479513_6	1317124.DW2_12255	1.402e-90	306.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2XMAG@285107|Thioclava	28211|Alphaproteobacteria	Q	Organic solvent ABC transporter ATP-binding protein	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WLSH2_k127_8536357_2	1027273.GZ77_23845	2.617e-69	248.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria,1SHHY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
WLSH2_k127_8536357_7	984262.SGRA_2277	2.266e-06	62.0	COG4886@1|root,COG4886@2|Bacteria,4NK2Y@976|Bacteroidetes,1IRQW@117747|Sphingobacteriia	976|Bacteroidetes	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	ko:K19613	ko04014,map04014	-	-	-	ko00000,ko00001	-	-	-	DUF1963,LRR_4,LRR_8
WLSH2_k127_8536357_3	1088869.GMO_23810	1.885e-18	102.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,2JSVP@204441|Rhodospirillales	204441|Rhodospirillales	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WLSH2_k127_8536357_4	985867.AEWF01000003_gene919	3.567e-17	81.0	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria,2VB37@28211|Alphaproteobacteria,47FTM@766|Rickettsiales	766|Rickettsiales	J	structural constituent of ribosome	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WLSH2_k127_8536357_1	985867.AEWF01000003_gene718	9.067e-83	292.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47FWS@766|Rickettsiales	766|Rickettsiales	EGP	COG0477 Permeases of the major facilitator superfamily	proP5	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_8536357_0	91604.ID47_11110	6.265e-95	325.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TQVP@28211|Alphaproteobacteria,47FWS@766|Rickettsiales	766|Rickettsiales	EGP	COG0477 Permeases of the major facilitator superfamily	proP5	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_8536357_5	227377.CBU_2021	3.482e-09	59.0	COG1373@1|root,COG1373@2|Bacteria,1R3UA@1224|Proteobacteria,1SAYB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_8604984_11	244581.IM40_03570	4.957e-07	57.0	2AG46@1|root,3168U@2|Bacteria,1Q7XX@1224|Proteobacteria,2VE39@28211|Alphaproteobacteria,47G7N@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8604984_3	244582.JQAK01000001_gene1663	1.229e-76	264.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2TRHN@28211|Alphaproteobacteria,47FDY@766|Rickettsiales	766|Rickettsiales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
WLSH2_k127_8604984_6	985867.AEWF01000004_gene173	1.144e-56	206.0	COG1261@1|root,COG1261@2|Bacteria,1PRX2@1224|Proteobacteria,2V44S@28211|Alphaproteobacteria,47FSG@766|Rickettsiales	766|Rickettsiales	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
WLSH2_k127_8604984_2	91604.ID47_00160	4.466e-94	315.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2TRR4@28211|Alphaproteobacteria,47FBX@766|Rickettsiales	766|Rickettsiales	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WLSH2_k127_8604984_5	91604.ID47_00165	1.293e-58	211.0	COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,2U06G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgF	-	-	ko:K02391,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WLSH2_k127_8604984_8	244582.JQAK01000001_gene1706	1.238e-36	152.0	COG3334@1|root,COG3334@2|Bacteria,1RKF6@1224|Proteobacteria,2TRR1@28211|Alphaproteobacteria,47FUV@766|Rickettsiales	766|Rickettsiales	S	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
WLSH2_k127_8604984_9	985867.AEWF01000003_gene705	8.808e-35	141.0	2BP2J@1|root,32HT5@2|Bacteria,1Q1JG@1224|Proteobacteria,2V60W@28211|Alphaproteobacteria,47FS3@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8604984_0	91604.ID47_09560	1.311e-132	432.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2TR4F@28211|Alphaproteobacteria,47F3N@766|Rickettsiales	766|Rickettsiales	N	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
WLSH2_k127_8604984_7	985867.AEWF01000003_gene707	1.512e-47	176.0	COG1580@1|root,COG1580@2|Bacteria,1RH5C@1224|Proteobacteria,2V36J@28211|Alphaproteobacteria,47FP7@766|Rickettsiales	766|Rickettsiales	N	Flagellar basal body-associated protein FliL	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
WLSH2_k127_8604984_1	91604.ID47_00245	3.162e-126	411.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2TRT6@28211|Alphaproteobacteria,47F47@766|Rickettsiales	766|Rickettsiales	M	Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WLSH2_k127_8604984_4	985867.AEWF01000003_gene715	7.794e-69	241.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,2V8RN@28211|Alphaproteobacteria,47F9D@766|Rickettsiales	766|Rickettsiales	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_8665575_5	91604.ID47_05865	4.609e-108	355.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,47F5X@766|Rickettsiales	766|Rickettsiales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH2_k127_8665575_9	244582.JQAK01000004_gene162	2.34e-79	276.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2TRHW@28211|Alphaproteobacteria,47F8U@766|Rickettsiales	766|Rickettsiales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
WLSH2_k127_8665575_13	985867.AEWF01000001_gene2157	3.701e-42	157.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,47FFJ@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
WLSH2_k127_8665575_11	91604.ID47_03290	9.657e-65	227.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria,47FDH@766|Rickettsiales	766|Rickettsiales	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WLSH2_k127_8665575_7	91604.ID47_03285	6.135e-88	292.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,47F77@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3,1.6.99.3	ko:K00338,ko:K03941	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	Fer4
WLSH2_k127_8665575_4	244582.JQAK01000001_gene694	5.943e-172	544.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,47EYG@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WLSH2_k127_8665575_0	985867.AEWF01000001_gene2153	8.732e-318	985.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,47F11@766|Rickettsiales	766|Rickettsiales	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C
WLSH2_k127_8665575_1	91604.ID47_03270	2.093e-236	735.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria,47EVE@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WLSH2_k127_8665575_10	244582.JQAK01000001_gene691	2.958e-75	259.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,47F8V@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)	nuoE	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
WLSH2_k127_8665575_2	985867.AEWF01000001_gene2150	5.988e-213	666.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,47ET3@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
WLSH2_k127_8665575_8	91604.ID47_03255	1.154e-84	286.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2TSMT@28211|Alphaproteobacteria,47FCH@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
WLSH2_k127_8665575_6	985867.AEWF01000001_gene2148	2.299e-99	327.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2TQK3@28211|Alphaproteobacteria,47EZV@766|Rickettsiales	766|Rickettsiales	C	Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3,1.6.99.3	ko:K00331,ko:K03940	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	Oxidored_q6
WLSH2_k127_8665575_12	244582.JQAK01000001_gene687	2.911e-57	201.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria,47FH2@766|Rickettsiales	766|Rickettsiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WLSH2_k127_8665575_3	985867.AEWF01000002_gene1544	4.526e-192	604.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,47F3C@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WLSH2_k127_8695560_2	985867.AEWF01000002_gene1491	4.838e-80	275.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,47FD5@766|Rickettsiales	766|Rickettsiales	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
WLSH2_k127_8695560_4	244582.JQAK01000004_gene315	3.034e-39	151.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,47FNC@766|Rickettsiales	766|Rickettsiales	S	Belongs to the HesB IscA family	iscA1	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
WLSH2_k127_8695560_6	244582.JQAK01000001_gene1530	1.404e-16	92.0	COG1404@1|root,COG1404@2|Bacteria,1PU89@1224|Proteobacteria,2V606@28211|Alphaproteobacteria,47GI4@766|Rickettsiales	766|Rickettsiales	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8695560_5	91604.ID47_09920	2.647e-38	154.0	COG0671@1|root,COG0671@2|Bacteria,1NCHC@1224|Proteobacteria,2UH7U@28211|Alphaproteobacteria,47FR9@766|Rickettsiales	766|Rickettsiales	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WLSH2_k127_8695560_0	91604.ID47_09910	2.925e-304	947.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,2TRCZ@28211|Alphaproteobacteria,47FZ3@766|Rickettsiales	766|Rickettsiales	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
WLSH2_k127_8695560_1	91604.ID47_09030	6.413e-83	278.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,47F9H@766|Rickettsiales	766|Rickettsiales	O	COG0694 Thioredoxin-like proteins and domains	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
WLSH2_k127_8695560_3	91604.ID47_09035	4.14e-50	188.0	COG0741@1|root,COG0741@2|Bacteria,1Q4YY@1224|Proteobacteria,2VBDF@28211|Alphaproteobacteria,47G5M@766|Rickettsiales	766|Rickettsiales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WLSH2_k127_8714277_10	231434.JQJH01000011_gene3217	0.0001015	53.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,3NBMX@45404|Beijerinckiaceae	28211|Alphaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH2_k127_8714277_3	91604.ID47_01910	2.061e-36	144.0	2AKR0@1|root,31BHU@2|Bacteria,1Q7CN@1224|Proteobacteria,2VDHJ@28211|Alphaproteobacteria,47GAJ@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8714277_1	985867.AEWF01000001_gene1783	5.837e-74	259.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K11066	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
WLSH2_k127_8714277_4	244581.IM40_06825	8.809e-31	134.0	COG5599@1|root,COG5599@2|Bacteria,1QU22@1224|Proteobacteria,2TXC7@28211|Alphaproteobacteria,47GTG@766|Rickettsiales	1224|Proteobacteria	T	Inositol hexakisphosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTPlike_phytase
WLSH2_k127_8714277_0	244582.JQAK01000001_gene1751	0.0	1509.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria,47EUX@766|Rickettsiales	766|Rickettsiales	I	COG0477 Permeases of the major facilitator superfamily	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
WLSH2_k127_8714277_6	1437425.CSEC_2024	1.705e-18	88.0	2ET5D@1|root,33KPF@2|Bacteria,2JHBU@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8714277_8	6239.T08B1.4b	9.61e-06	58.0	KOG4569@1|root,KOG4569@2759|Eukaryota,39G5H@33154|Opisthokonta,3C1H6@33208|Metazoa,3DHVZ@33213|Bilateria,40GIW@6231|Nematoda,1KZKP@119089|Chromadorea,40TD9@6236|Rhabditida	33208|Metazoa	G	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
WLSH2_k127_8714277_2	985867.AEWF01000001_gene2068	4.82e-63	223.0	COG5385@1|root,COG5385@2|Bacteria	2|Bacteria	S	Histidine phosphotransferase C-terminal domain	chpT	-	-	ko:K13588	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001	-	-	-	HPTransfase
WLSH2_k127_8714277_9	1144888.CM001467_gene914	5.401e-05	46.0	COG1373@1|root,COG1373@2|Bacteria,1NQGE@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
WLSH2_k127_8714277_7	65393.PCC7424_5660	7.867e-10	67.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,3KHBS@43988|Cyanothece	1117|Cyanobacteria	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
WLSH2_k127_8714277_5	331869.BAL199_30477	9.416e-24	108.0	COG5433@1|root,COG5433@2|Bacteria,1PY8T@1224|Proteobacteria,2UGIG@28211|Alphaproteobacteria,4BT36@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
WLSH2_k127_8760973_7	469595.CSAG_04150	8.232e-65	228.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,3WY8H@544|Citrobacter	1236|Gammaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,HTH_32,rve
WLSH2_k127_8760973_2	244582.JQAK01000001_gene1780	1.768e-88	301.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria,47FZH@766|Rickettsiales	766|Rickettsiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_8760973_3	244582.JQAK01000001_gene960	7.581e-84	293.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,47F0S@766|Rickettsiales	766|Rickettsiales	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
WLSH2_k127_8760973_8	985867.AEWF01000001_gene2004	3.66e-50	184.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
WLSH2_k127_8760973_9	1196324.A374_03394	1.425e-28	117.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hbs	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WLSH2_k127_8760973_6	244582.JQAK01000004_gene293	5.522e-69	245.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2TRTG@28211|Alphaproteobacteria,47F9C@766|Rickettsiales	766|Rickettsiales	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
WLSH2_k127_8760973_1	91604.ID47_04340	1.994e-201	634.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,47F7A@766|Rickettsiales	766|Rickettsiales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	argD	-	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_8760973_0	244582.JQAK01000001_gene1694	7.294e-241	753.0	COG3202@1|root,COG3202@2|Bacteria,1MVS9@1224|Proteobacteria,2TSSJ@28211|Alphaproteobacteria,47EX6@766|Rickettsiales	766|Rickettsiales	C	Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism	tlc1	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006862,GO:0008150,GO:0015711,GO:0015748,GO:0015865,GO:0015867,GO:0015868,GO:0015893,GO:0015931,GO:0016020,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051503,GO:0071702,GO:0071705,GO:0071944,GO:1901264	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	TLC
WLSH2_k127_8760973_11	111780.Sta7437_2732	7.219e-21	108.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1GIUI@1117|Cyanobacteria,3VKVG@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,TPR_2
WLSH2_k127_8760973_5	985867.AEWF01000001_gene1743	7.832e-71	244.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria,47FEQ@766|Rickettsiales	766|Rickettsiales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WLSH2_k127_8760973_4	985867.AEWF01000001_gene1744	1.096e-81	273.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,47F97@766|Rickettsiales	766|Rickettsiales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WLSH2_k127_8760973_10	402881.Plav_2199	2.579e-27	113.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,1JPCP@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	Cold shock protein domain	MA20_28310	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WLSH2_k127_8775111_2	78898.MVEG_05746T0	9.96e-111	386.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38KU9@33154|Opisthokonta,3NXW6@4751|Fungi	4751|Fungi	AT	Mortierella verticillata NRRL 6337	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
WLSH2_k127_8775111_3	244582.JQAK01000001_gene1365	1.11e-103	341.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_5
WLSH2_k127_8775111_0	985867.AEWF01000004_gene222	2.454e-295	915.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,47FZ6@766|Rickettsiales	766|Rickettsiales	I	Acyl-CoA dehydrogenase N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
WLSH2_k127_8775111_1	91604.ID47_00495	8.138e-266	827.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria,47F0U@766|Rickettsiales	766|Rickettsiales	I	3-hydroxyacyl-CoA dehydrogenase	fadB	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782,ko:K07516	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04743,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
WLSH2_k127_8806943_2	579405.Dd703_3276	2.785e-71	245.0	COG0451@1|root,COG0451@2|Bacteria,1MVPZ@1224|Proteobacteria,1RYAV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	Epimerase dehydratase	rmd	-	1.1.1.135,1.1.1.271	ko:K02377,ko:K22252	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03396,R03398,R05692	RC00182,RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WLSH2_k127_8806943_1	1027273.GZ77_02315	1.812e-109	365.0	COG0438@1|root,COG0438@2|Bacteria,1P81Z@1224|Proteobacteria,1S2B8@1236|Gammaproteobacteria,1XN79@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH2_k127_8806943_0	857087.Metme_3646	1.033e-142	461.0	COG0438@1|root,COG0438@2|Bacteria,1MVB4@1224|Proteobacteria,1RNYM@1236|Gammaproteobacteria,1XGQ1@135618|Methylococcales	135618|Methylococcales	M	Glycosyl transferases group 1	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glycos_transf_1
WLSH2_k127_8806943_6	1411123.JQNH01000001_gene2114	2.767e-18	95.0	COG2959@1|root,COG2959@2|Bacteria	2|Bacteria	H	enzyme of heme biosynthesis	-	-	2.1.1.107,2.1.1.294,2.7.1.181,2.7.11.1	ko:K02496,ko:K05802,ko:K08884,ko:K18827	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194,R10657,R10658	RC00002,RC00003,RC00078,RC00871,RC03220	ko00000,ko00001,ko00002,ko01000,ko01001,ko01005,ko02000	1.A.23.1.1	-	-	DUF2570,DUF4012,HemX
WLSH2_k127_8806943_7	1282361.ABAC402_13585	8.162e-06	56.0	COG1360@1|root,COG1360@2|Bacteria,1RAGU@1224|Proteobacteria,2U71Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
WLSH2_k127_8806943_3	269799.Gmet_1337	3.825e-63	221.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42QSG@68525|delta/epsilon subdivisions,2WN24@28221|Deltaproteobacteria,43T8F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bacterial sugar transferase	-	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf
WLSH2_k127_8806943_5	767434.Fraau_2485	6.769e-49	180.0	COG0590@1|root,COG0590@2|Bacteria,1RFCW@1224|Proteobacteria,1S5YA@1236|Gammaproteobacteria,1XC1R@135614|Xanthomonadales	135614|Xanthomonadales	FJ	deaminase	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
WLSH2_k127_8806943_4	244582.JQAK01000001_gene1779	2.232e-55	196.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,47EZC@766|Rickettsiales	766|Rickettsiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WLSH2_k127_8831835_5	1380394.JADL01000010_gene4364	8.295e-73	254.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,2JRPG@204441|Rhodospirillales	204441|Rhodospirillales	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH2_k127_8831835_0	985867.AEWF01000004_gene286	4.008e-284	880.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2TS0R@28211|Alphaproteobacteria,47G1E@766|Rickettsiales	766|Rickettsiales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2
WLSH2_k127_8831835_4	244582.JQAK01000001_gene1594	9.575e-88	300.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,47FCB@766|Rickettsiales	766|Rickettsiales	S	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
WLSH2_k127_8831835_2	985867.AEWF01000004_gene233	3.52e-208	664.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,47ETE@766|Rickettsiales	766|Rickettsiales	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WLSH2_k127_8831835_1	414684.RC1_2006	6.603e-227	720.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,2JQ4J@204441|Rhodospirillales	204441|Rhodospirillales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH2_k127_8831835_3	244582.JQAK01000001_gene1042	8.518e-167	530.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,47F2Y@766|Rickettsiales	766|Rickettsiales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WLSH2_k127_8831835_6	985867.AEWF01000001_gene1756	7.524e-55	201.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2TWYJ@28211|Alphaproteobacteria,47GTR@766|Rickettsiales	766|Rickettsiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WLSH2_k127_89883_1	1122212.AULO01000012_gene1111	0.0003401	51.0	COG1073@1|root,COG1073@2|Bacteria,1QU04@1224|Proteobacteria,1T1JR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_89883_0	91604.ID47_11030	5.995e-252	785.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria,47EUA@766|Rickettsiales	766|Rickettsiales	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH2_k127_9008436_2	244581.IM40_01700	1.343e-55	208.0	COG3520@1|root,COG3520@2|Bacteria,1MWVS@1224|Proteobacteria,2U1QR@28211|Alphaproteobacteria,47FJC@766|Rickettsiales	766|Rickettsiales	S	Type VI secretion, TssG	-	-	-	ko:K11895	ko02025,map02025	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssG
WLSH2_k127_9008436_0	91604.ID47_09855	5.022e-259	814.0	COG3519@1|root,COG3519@2|Bacteria,1MUY4@1224|Proteobacteria,2TUGV@28211|Alphaproteobacteria,47ETI@766|Rickettsiales	766|Rickettsiales	S	Type VI secretion system, TssF	-	-	-	ko:K11896	-	M00334	-	-	ko00000,ko00002,ko02044	3.A.23.1	-	-	T6SS_TssF
WLSH2_k127_9008436_1	244582.JQAK01000004_gene289	3.24e-258	804.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,47EV6@766|Rickettsiales	766|Rickettsiales	I	propionyl-CoA carboxylase beta	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH2_k127_9143389_10	1054213.HMPREF9946_04402	7.783e-27	109.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,2JPKS@204441|Rhodospirillales	204441|Rhodospirillales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
WLSH2_k127_9143389_13	1410668.JNKC01000016_gene993	4.89e-05	46.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9143389_5	985867.AEWF01000002_gene1589	5.75e-90	302.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria,47FBR@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
WLSH2_k127_9143389_14	1211579.PP4_14950	8.79e-05	45.0	2AP99@1|root,31EB9@2|Bacteria,1RM04@1224|Proteobacteria,1S5Z7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9143389_1	985867.AEWF01000002_gene1588	4.148e-207	649.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2TR40@28211|Alphaproteobacteria,47FB7@766|Rickettsiales	766|Rickettsiales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
WLSH2_k127_9143389_2	91604.ID47_00745	1.002e-178	568.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria,47F0Z@766|Rickettsiales	766|Rickettsiales	P	domain protein	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WLSH2_k127_9143389_8	91604.ID47_03915	4.569e-45	173.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,2U7AP@28211|Alphaproteobacteria,47FFP@766|Rickettsiales	766|Rickettsiales	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WLSH2_k127_9143389_3	985867.AEWF01000007_gene368	3.011e-124	408.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,47FAK@766|Rickettsiales	766|Rickettsiales	S	Permease	perM	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
WLSH2_k127_9143389_7	244582.JQAK01000001_gene749	1.079e-47	179.0	COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,47FFT@766|Rickettsiales	766|Rickettsiales	L	ATPase involved in DNA replication initiation	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA
WLSH2_k127_9143389_9	244582.JQAK01000001_gene755	1.298e-31	124.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria,47FKV@766|Rickettsiales	766|Rickettsiales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH2_k127_9143389_0	91604.ID47_08015	3.933e-216	676.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TR32@28211|Alphaproteobacteria,47F0E@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH2_k127_9143389_6	985867.AEWF01000006_gene528	2.911e-66	228.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,47FEK@766|Rickettsiales	766|Rickettsiales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WLSH2_k127_9143389_11	1232410.KI421413_gene775	2.807e-06	51.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_9,Response_reg
WLSH2_k127_9143389_4	1122165.AUHS01000004_gene3159	9.756e-94	317.0	COG2826@1|root,COG2826@2|Bacteria,1MWI0@1224|Proteobacteria,1RRSE@1236|Gammaproteobacteria,1JEXQ@118969|Legionellales	118969|Legionellales	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
WLSH2_k127_9162936_2	883126.HMPREF9710_04992	2.482e-49	184.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,2VPCI@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,HTH_29,HTH_32,rve
WLSH2_k127_9162936_3	1416760.AYMS01000156_gene1806	3.622e-07	52.0	COG3385@1|root,COG3385@2|Bacteria,4NNZ7@976|Bacteroidetes,1I7YK@117743|Flavobacteriia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_9162936_4	1189620.AJXL01000220_gene3127	1.046e-06	54.0	COG3385@1|root,COG3385@2|Bacteria,4NNZ7@976|Bacteroidetes,1I7YK@117743|Flavobacteriia,2NZAM@237|Flavobacterium	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_9162936_0	153948.NAL212_2251	1.86e-144	473.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2VHIG@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
WLSH2_k127_9162936_1	1337093.MBE-LCI_3428	4.509e-75	261.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2V7ZJ@28211|Alphaproteobacteria,2PA1C@245186|Loktanella	28211|Alphaproteobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
WLSH2_k127_9181525_5	1348663.KCH_77290	1.402e-08	66.0	COG1051@1|root,COG4639@1|root,COG1051@2|Bacteria,COG4639@2|Bacteria,2IK42@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	ATP_bind_2,NUDIX
WLSH2_k127_9181525_1	292415.Tbd_1082	3.085e-140	455.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH2_k127_9181525_3	1122137.AQXF01000005_gene1117	9.789e-107	353.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	ABC transporter	MA20_09455	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_9181525_4	159450.NH14_19310	4.862e-60	220.0	COG0845@1|root,COG0845@2|Bacteria,1R3U4@1224|Proteobacteria,2VNQ2@28216|Betaproteobacteria,1K0P5@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
WLSH2_k127_9181525_0	91604.ID47_06915	2.414e-194	614.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2TRXU@28211|Alphaproteobacteria,47EUF@766|Rickettsiales	766|Rickettsiales	NU	ATP synthase alpha/beta family, nucleotide-binding domain	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WLSH2_k127_9181525_2	985867.AEWF01000002_gene1636	4.651e-133	427.0	COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,47EUZ@766|Rickettsiales	766|Rickettsiales	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ctrA	-	-	ko:K02483,ko:K13584	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_9201504_3	985867.AEWF01000003_gene807	1.394e-208	662.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2U258@28211|Alphaproteobacteria,47F16@766|Rickettsiales	766|Rickettsiales	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
WLSH2_k127_9201504_2	290315.Clim_1364	3.843e-211	666.0	COG0415@1|root,COG0415@2|Bacteria,1FEBK@1090|Chlorobi	1090|Chlorobi	H	DNA photolyase domain protein	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
WLSH2_k127_9201504_14	313612.L8106_00480	1.089e-05	55.0	COG1525@1|root,COG1525@2|Bacteria,1G54G@1117|Cyanobacteria,1HANT@1150|Oscillatoriales	1117|Cyanobacteria	L	Micrococcal nuclease (thermonuclease) homologs	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
WLSH2_k127_9201504_15	1158294.JOMI01000003_gene2329	1.332e-05	55.0	COG1525@1|root,COG1525@2|Bacteria,4NT0S@976|Bacteroidetes,2FXU2@200643|Bacteroidia	976|Bacteroidetes	L	Staphylococcal nuclease homologues	lpxP	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
WLSH2_k127_9201504_4	1528106.JRJE01000031_gene3256	2.445e-185	607.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2TU7G@28211|Alphaproteobacteria,2JQT9@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
WLSH2_k127_9201504_1	985867.AEWF01000001_gene1785	1.654e-212	668.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,47EXA@766|Rickettsiales	766|Rickettsiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WLSH2_k127_9201504_7	91604.ID47_03510	3.339e-120	392.0	COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,47FX5@766|Rickettsiales	766|Rickettsiales	D	FtsX-like permease family	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
WLSH2_k127_9201504_6	985867.AEWF01000006_gene617	1.259e-120	392.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria,47F9Z@766|Rickettsiales	766|Rickettsiales	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WLSH2_k127_9201504_0	985867.AEWF01000006_gene603	4.947e-236	735.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,47EUJ@766|Rickettsiales	766|Rickettsiales	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WLSH2_k127_9201504_12	596152.DesU5LDRAFT_3950	7.509e-07	53.0	COG3847@1|root,COG3847@2|Bacteria,1NGVU@1224|Proteobacteria,42X6U@68525|delta/epsilon subdivisions,2WSP7@28221|Deltaproteobacteria,2MDVB@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
WLSH2_k127_9201504_11	1101190.ARWB01000001_gene1312	9.394e-09	63.0	COG4961@1|root,COG4961@2|Bacteria,1N0M1@1224|Proteobacteria,2UCUG@28211|Alphaproteobacteria,370WY@31993|Methylocystaceae	28211|Alphaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
WLSH2_k127_9201504_10	1122135.KB893134_gene3957	2.824e-15	83.0	COG4961@1|root,COG4961@2|Bacteria,1N654@1224|Proteobacteria,2UEG6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
WLSH2_k127_9201504_8	244581.IM40_03465	1.629e-103	353.0	COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Flp pilus assembly protein TadG	-	-	-	-	-	-	-	-	-	-	-	-	Tad
WLSH2_k127_9201504_9	244581.IM40_03465	1.457e-94	327.0	COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Flp pilus assembly protein TadG	-	-	-	-	-	-	-	-	-	-	-	-	Tad
WLSH2_k127_9201504_5	1123401.JHYQ01000021_gene1025	5.823e-162	520.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,45ZYU@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_9244315_16	857087.Metme_2203	3.886e-57	203.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,1RSJY@1236|Gammaproteobacteria,1XFE6@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
WLSH2_k127_9244315_4	985867.AEWF01000001_gene1945	1.709e-148	484.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,47G0T@766|Rickettsiales	766|Rickettsiales	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
WLSH2_k127_9244315_21	1238182.C882_0226	1.199e-30	138.0	COG1198@1|root,COG1198@2|Bacteria,1QU4F@1224|Proteobacteria,2UAXK@28211|Alphaproteobacteria,2JXTU@204441|Rhodospirillales	204441|Rhodospirillales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9244315_14	1238182.C882_0225	4.388e-62	230.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2TVZ5@28211|Alphaproteobacteria,2JUHI@204441|Rhodospirillales	204441|Rhodospirillales	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
WLSH2_k127_9244315_26	990073.ATHU01000001_gene1068	0.0009364	51.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42RGM@68525|delta/epsilon subdivisions,2YPC6@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	V	HlyD family secretion protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	HlyD_3,HlyD_D23
WLSH2_k127_9244315_10	91604.ID47_01855	6.297e-86	291.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria,47FEF@766|Rickettsiales	766|Rickettsiales	S	Metal-dependent hydrolases of the beta-lactamase superfamily I	phnP	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
WLSH2_k127_9244315_25	6211.A0A068Y871	7.231e-05	54.0	KOG4308@1|root,KOG4308@2759|Eukaryota,38H8T@33154|Opisthokonta,3BB2P@33208|Metazoa,3D25Z@33213|Bilateria	33208|Metazoa	S	cell differentiation	LRRC34	-	-	-	-	-	-	-	-	-	-	-	LRR_6
WLSH2_k127_9244315_3	754476.Q7A_193	1.218e-189	604.0	COG3177@1|root,COG3177@2|Bacteria,1MVW0@1224|Proteobacteria,1RYFI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
WLSH2_k127_9244315_0	91604.ID47_11785	1.586e-290	905.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,47ET4@766|Rickettsiales	766|Rickettsiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
WLSH2_k127_9244315_23	1208583.COMX_05130	4.211e-07	63.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
WLSH2_k127_9244315_24	765952.PUV_08390	7.826e-06	58.0	COG0790@1|root,COG0790@2|Bacteria,2JGIF@204428|Chlamydiae	204428|Chlamydiae	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
WLSH2_k127_9244315_20	91604.ID47_08980	1.736e-37	150.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,47FNY@766|Rickettsiales	766|Rickettsiales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WLSH2_k127_9244315_8	985867.AEWF01000002_gene1342	2.937e-119	387.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,47ET9@766|Rickettsiales	766|Rickettsiales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WLSH2_k127_9244315_13	91604.ID47_09260	1.657e-66	230.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,47FFN@766|Rickettsiales	766|Rickettsiales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WLSH2_k127_9244315_9	91604.ID47_02720	3.399e-97	326.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria,47F87@766|Rickettsiales	766|Rickettsiales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_9244315_5	244582.JQAK01000001_gene1106	1.017e-145	472.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,47EXN@766|Rickettsiales	766|Rickettsiales	E	Threonine dehydratase	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_9244315_22	588581.Cpap_0278	3.464e-22	113.0	COG3621@1|root,COG3621@2|Bacteria,1UYFU@1239|Firmicutes,25DW4@186801|Clostridia	186801|Clostridia	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WLSH2_k127_9244315_12	985867.AEWF01000001_gene1795	3.303e-67	254.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	Patatin
WLSH2_k127_9244315_1	91604.ID47_02290	3.156e-220	704.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,47G2Z@766|Rickettsiales	766|Rickettsiales	I	Biotin carboxylase C-terminal domain	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
WLSH2_k127_9244315_7	91604.ID47_11970	4.536e-136	439.0	COG3654@1|root,COG3943@1|root,COG3654@2|Bacteria,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,2TU1T@28211|Alphaproteobacteria,47FHS@766|Rickettsiales	766|Rickettsiales	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Virulence_RhuM
WLSH2_k127_9244315_6	91604.ID47_03450	5.475e-139	464.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria,47F8X@766|Rickettsiales	766|Rickettsiales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
WLSH2_k127_9244315_11	91604.ID47_02125	1.263e-74	254.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2U6ZT@28211|Alphaproteobacteria,47FDI@766|Rickettsiales	766|Rickettsiales	O	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
WLSH2_k127_9244315_15	91604.ID47_03200	8.403e-59	209.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,47GSZ@766|Rickettsiales	766|Rickettsiales	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
WLSH2_k127_9244315_2	244582.JQAK01000001_gene1562	4.063e-212	676.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,2TUB2@28211|Alphaproteobacteria,47F1B@766|Rickettsiales	766|Rickettsiales	S	Phage late control gene D protein (GPD)	-	-	-	ko:K11904	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	Phage_GPD
WLSH2_k127_9244315_17	709032.Sulku_0484	1.268e-48	183.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,42MSW@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
WLSH2_k127_9244315_18	244582.JQAK01000001_gene1944	2.544e-42	157.0	COG1742@1|root,COG1742@2|Bacteria,1MZI8@1224|Proteobacteria,2UBWY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	UPF0060 membrane protein	-	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
WLSH2_k127_9246090_5	244582.JQAK01000001_gene1482	1.265e-109	356.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,47F6P@766|Rickettsiales	766|Rickettsiales	C	radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WLSH2_k127_9246090_0	91604.ID47_00685	0.0	1572.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,47EXC@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH2_k127_9246090_16	43151.ADAC001750-PA	6.632e-05	53.0	COG4886@1|root,KOG0619@2759|Eukaryota,39XNU@33154|Opisthokonta,3BMXY@33208|Metazoa,3D0K1@33213|Bilateria,41Y9A@6656|Arthropoda,3SKC5@50557|Insecta,451P4@7147|Diptera,45CMA@7148|Nematocera	33208|Metazoa	U	Leucine-rich transmembrane protein	-	GO:0000902,GO:0007275,GO:0007399,GO:0008150,GO:0009653,GO:0009987,GO:0016043,GO:0022008,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0048468,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0071840,GO:0120036,GO:0120039	-	-	-	-	-	-	-	-	-	-	I-set,Ig_3,LRR_8
WLSH2_k127_9246090_8	91604.ID47_00685	3.523e-80	283.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,47EXC@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH2_k127_9246090_14	870187.Thini_3690	1.373e-19	102.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,461DX@72273|Thiotrichales	72273|Thiotrichales	I	aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
WLSH2_k127_9246090_4	91604.ID47_06630	1.547e-137	447.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,47F5S@766|Rickettsiales	766|Rickettsiales	H	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WLSH2_k127_9246090_11	244582.JQAK01000001_gene2008	1.433e-49	184.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2U5V2@28211|Alphaproteobacteria,47FFU@766|Rickettsiales	766|Rickettsiales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WLSH2_k127_9246090_15	1034943.BN1094_00732	2.417e-16	87.0	2APSB@1|root,31EWC@2|Bacteria,1QC8U@1224|Proteobacteria,1T7Y8@1236|Gammaproteobacteria,1JG0W@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9246090_1	244582.JQAK01000001_gene1230	0.0	1015.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,47EUN@766|Rickettsiales	766|Rickettsiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WLSH2_k127_9246090_3	244582.JQAK01000001_gene1229	1.103e-145	464.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,47EX7@766|Rickettsiales	766|Rickettsiales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_17,Fer4_8
WLSH2_k127_9246090_10	306264.CUP0830	7.815e-72	253.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2YMPY@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WLSH2_k127_9246090_12	985867.AEWF01000002_gene1431	1.035e-32	129.0	COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,47FNF@766|Rickettsiales	766|Rickettsiales	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
WLSH2_k127_9246090_7	91604.ID47_08960	2.06e-91	310.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,47EXQ@766|Rickettsiales	766|Rickettsiales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WLSH2_k127_9246090_2	244582.JQAK01000001_gene2022	5.321e-158	506.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,47EVJ@766|Rickettsiales	766|Rickettsiales	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WLSH2_k127_9246090_9	91604.ID47_02330	8.912e-77	261.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2TTX4@28211|Alphaproteobacteria,47FJH@766|Rickettsiales	766|Rickettsiales	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
WLSH2_k127_9246090_6	91604.ID47_05875	1.842e-91	307.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,47FB4@766|Rickettsiales	766|Rickettsiales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WLSH2_k127_9363056_2	588596.U9TWX4	2.451e-49	199.0	COG0515@1|root,COG0790@1|root,KOG0192@2759|Eukaryota,KOG1550@2759|Eukaryota,38DA9@33154|Opisthokonta	33154|Opisthokonta	MOT	fungal-type cell wall polysaccharide biosynthetic process	CHS4	GO:0000003,GO:0000131,GO:0000271,GO:0003006,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005628,GO:0005933,GO:0005935,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006030,GO:0006031,GO:0006037,GO:0006038,GO:0006040,GO:0006807,GO:0007049,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009272,GO:0009653,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0017144,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030234,GO:0030427,GO:0030435,GO:0030437,GO:0032502,GO:0032505,GO:0033692,GO:0034221,GO:0034293,GO:0034637,GO:0034645,GO:0042546,GO:0042763,GO:0042764,GO:0043085,GO:0043170,GO:0043934,GO:0043935,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044464,GO:0044703,GO:0046349,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0050790,GO:0051278,GO:0051321,GO:0051704,GO:0065007,GO:0065009,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071852,GO:0071966,GO:0098772,GO:1901071,GO:1901073,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903046	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
WLSH2_k127_9363056_1	985867.AEWF01000004_gene87	1.917e-193	613.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,2TSHG@28211|Alphaproteobacteria,47F0V@766|Rickettsiales	766|Rickettsiales	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
WLSH2_k127_9363056_4	985867.AEWF01000001_gene2278	3.249e-26	114.0	COG4731@1|root,COG4731@2|Bacteria,1Q3TW@1224|Proteobacteria,2VAFQ@28211|Alphaproteobacteria,47GGY@766|Rickettsiales	766|Rickettsiales	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
WLSH2_k127_9363056_0	91604.ID47_11500	8.133e-255	801.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2TRPY@28211|Alphaproteobacteria,47EWG@766|Rickettsiales	766|Rickettsiales	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH2_k127_9363056_5	452471.Aasi_0461	3.568e-20	104.0	COG0790@1|root,COG4115@1|root,COG0790@2|Bacteria,COG4115@2|Bacteria	2|Bacteria	D	mRNA cleavage	-	-	-	ko:K07126,ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Sel1,YoeB_toxin
WLSH2_k127_9532524_2	264203.ZMO0137	1.267e-11	78.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2K2V2@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
WLSH2_k127_9532524_0	985867.AEWF01000001_gene1852	1.297e-270	857.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,47G46@766|Rickettsiales	766|Rickettsiales	K	RNB	-	-	-	-	-	-	-	-	-	-	-	-	RNB,S1
WLSH2_k127_9532524_3	7994.ENSAMXP00000009052	1.78e-10	71.0	COG4886@1|root,KOG0619@2759|Eukaryota,38G9U@33154|Opisthokonta,3BCFH@33208|Metazoa,3CUNN@33213|Bilateria,4855J@7711|Chordata,490NA@7742|Vertebrata,49VGZ@7898|Actinopterygii	33208|Metazoa	S	Leucine rich repeat containing	LRRC58	-	-	-	-	-	-	-	-	-	-	-	LRR_1,LRR_4,LRR_6,LRR_8
WLSH2_k127_9532524_1	91604.ID47_00410	2.659e-73	262.0	COG0814@1|root,COG0814@2|Bacteria,1N35H@1224|Proteobacteria,2UDY2@28211|Alphaproteobacteria,47F6E@766|Rickettsiales	766|Rickettsiales	E	Tryptophan/tyrosine permease family	-	-	-	ko:K03834	-	-	-	-	ko00000,ko02000	2.A.42.1.1	-	-	Trp_Tyr_perm
WLSH2_k127_955197_0	1178540.BA70_06775	3.043e-21	98.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli,1ZAUZ@1386|Bacillus	91061|Bacilli	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_9558743_2	1268635.Loa_01276	2.895e-137	450.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1RMSZ@1236|Gammaproteobacteria,1JDX0@118969|Legionellales	118969|Legionellales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_9558743_5	91604.ID47_09960	9.995e-47	174.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,47FMK@766|Rickettsiales	766|Rickettsiales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
WLSH2_k127_9558743_0	244582.JQAK01000001_gene1762	6.583e-247	767.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,47GT0@766|Rickettsiales	766|Rickettsiales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WLSH2_k127_9558743_3	91604.ID47_06365	1.354e-94	313.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2TRZM@28211|Alphaproteobacteria,47F94@766|Rickettsiales	766|Rickettsiales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
WLSH2_k127_9558743_4	985867.AEWF01000001_gene1737	3.022e-59	217.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,47FII@766|Rickettsiales	766|Rickettsiales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
WLSH2_k127_9558743_1	985867.AEWF01000005_gene2466	1.355e-183	580.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2U050@28211|Alphaproteobacteria,47FW5@766|Rickettsiales	766|Rickettsiales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_9630867_12	91604.ID47_09160	1.267e-23	112.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2TSF2@28211|Alphaproteobacteria,47FQP@766|Rickettsiales	766|Rickettsiales	N	Flagellar basal body protein FlaE	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bbr_C
WLSH2_k127_9630867_7	91604.ID47_03430	3.601e-95	318.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria,47FA2@766|Rickettsiales	766|Rickettsiales	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WLSH2_k127_9630867_4	414684.RC1_1215	4.587e-134	439.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,2JPQR@204441|Rhodospirillales	204441|Rhodospirillales	M	COG4591 ABC-type transport system, involved in lipoprotein release, permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WLSH2_k127_9630867_11	91604.ID47_06060	1.654e-24	106.0	COG4530@1|root,COG4530@2|Bacteria,1Q76M@1224|Proteobacteria,2VDB2@28211|Alphaproteobacteria,47FUF@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
WLSH2_k127_9630867_2	985867.AEWF01000003_gene960	1.21e-168	539.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,47EY2@766|Rickettsiales	766|Rickettsiales	H	5-aminolevulinic acid synthase	hemA	-	2.3.1.37	ko:K00643	ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110	-	R00830	RC00004,RC02815	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_9630867_10	985867.AEWF01000003_gene889	8.731e-33	130.0	COG5349@1|root,COG5349@2|Bacteria,1Q3BY@1224|Proteobacteria,2VA8E@28211|Alphaproteobacteria,47GEZ@766|Rickettsiales	766|Rickettsiales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
WLSH2_k127_9630867_5	244582.JQAK01000001_gene1823	1.418e-110	364.0	COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the 3-hydroxyisobutyrate dehydrogenase family	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WLSH2_k127_9630867_1	91604.ID47_10985	3.013e-229	719.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,47GQ9@766|Rickettsiales	766|Rickettsiales	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH2_k127_9630867_3	1122135.KB893168_gene1931	1.908e-148	479.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the thiolase family	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_9630867_0	91604.ID47_04220	0.0	1131.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,47EW5@766|Rickettsiales	766|Rickettsiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
WLSH2_k127_9630867_6	244582.JQAK01000001_gene1023	2.278e-103	348.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,47EX0@766|Rickettsiales	766|Rickettsiales	LU	DNA processing protein	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
WLSH2_k127_9630867_8	244582.JQAK01000004_gene262	1.535e-87	305.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Porin_2
WLSH2_k127_9630867_14	91604.ID47_10830	2.358e-16	88.0	2AJH8@1|root,31A3T@2|Bacteria,1Q4VH@1224|Proteobacteria,2VBA5@28211|Alphaproteobacteria,47G5J@766|Rickettsiales	766|Rickettsiales	S	OmpA-like transmembrane domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
WLSH2_k127_9630867_9	244582.JQAK01000001_gene2105	2.224e-64	230.0	COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria,47FG3@766|Rickettsiales	766|Rickettsiales	G	sugar phosphatases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
WLSH2_k127_9630867_13	985867.AEWF01000002_gene1423	3.387e-23	106.0	2AEZE@1|root,314XF@2|Bacteria,1PUVI@1224|Proteobacteria,2V6DM@28211|Alphaproteobacteria,47G8K@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9712920_2	244582.JQAK01000004_gene152	1.025e-170	546.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,2TQVA@28211|Alphaproteobacteria,47GE0@766|Rickettsiales	766|Rickettsiales	U	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
WLSH2_k127_9712920_0	985867.AEWF01000003_gene983	0.0	1682.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,47G2C@766|Rickettsiales	766|Rickettsiales	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	POR,TPP_enzyme_C
WLSH2_k127_9712920_7	1094980.Mpsy_2551	0.0001352	52.0	COG0484@1|root,arCOG06880@1|root,arCOG02846@2157|Archaea,arCOG06880@2157|Archaea,2XV5D@28890|Euryarchaeota,2N95Q@224756|Methanomicrobia	224756|Methanomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH2_k127_9712920_5	4555.Si022453m	1.854e-06	58.0	COG0484@1|root,KOG0714@2759|Eukaryota,37KKV@33090|Viridiplantae,3GAHE@35493|Streptophyta,3M25X@4447|Liliopsida,3I45S@38820|Poales	35493|Streptophyta	O	DnaJ C terminal domain	-	-	-	ko:K09510	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,DnaJ_C
WLSH2_k127_9712920_8	985867.AEWF01000002_gene1441	0.0007927	52.0	2ADBU@1|root,31319@2|Bacteria,1PRKQ@1224|Proteobacteria,2V3VQ@28211|Alphaproteobacteria,47G5W@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9712920_6	985867.AEWF01000002_gene1439	1.005e-05	58.0	2AKQP@1|root,31BHF@2|Bacteria,1Q7CB@1224|Proteobacteria,2VDH5@28211|Alphaproteobacteria,47G9P@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9712920_3	985867.AEWF01000001_gene1973	2.915e-113	376.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2TS13@28211|Alphaproteobacteria,47F40@766|Rickettsiales	766|Rickettsiales	NU	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
WLSH2_k127_9712920_1	244582.JQAK01000001_gene776	2.477e-284	889.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,47EUH@766|Rickettsiales	766|Rickettsiales	L	Has both ATPase and helicase activities. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair (By similarity)	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH2_k127_9712920_4	648757.Rvan_1972	4.695e-55	200.0	COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,2UBIJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	PFAM SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
WLSH2_k127_971674_13	643648.Slip_1917	1.718e-12	77.0	COG2064@1|root,COG2064@2|Bacteria,1V2T1@1239|Firmicutes,24GQ4@186801|Clostridia,42KJZ@68298|Syntrophomonadaceae	186801|Clostridia	NU	PFAM type II secretion system	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
WLSH2_k127_971674_3	91604.ID47_09125	1.303e-87	293.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,47FHJ@766|Rickettsiales	766|Rickettsiales	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WLSH2_k127_971674_0	244582.JQAK01000001_gene1518	6.357e-161	514.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria,47F13@766|Rickettsiales	766|Rickettsiales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
WLSH2_k127_971674_9	985867.AEWF01000002_gene1496	5.034e-34	133.0	2BKF2@1|root,32EVU@2|Bacteria,1Q0BV@1224|Proteobacteria,2V5T4@28211|Alphaproteobacteria,47GBT@766|Rickettsiales	766|Rickettsiales	S	Rod binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
WLSH2_k127_971674_11	91604.ID47_11905	3.823e-21	98.0	2A9YD@1|root,30Z6K@2|Bacteria,1NJP8@1224|Proteobacteria,2UNC3@28211|Alphaproteobacteria,47GCA@766|Rickettsiales	766|Rickettsiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_971674_1	985867.AEWF01000002_gene1494	8.432e-137	456.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2TV1B@28211|Alphaproteobacteria,47FNU@766|Rickettsiales	766|Rickettsiales	N	flagellar hook-associated protein	-	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
WLSH2_k127_971674_4	91604.ID47_11915	3.073e-71	251.0	COG1344@1|root,COG1344@2|Bacteria,1PS3Y@1224|Proteobacteria,2V4AX@28211|Alphaproteobacteria,47FXD@766|Rickettsiales	766|Rickettsiales	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_971674_10	985867.AEWF01000002_gene1492	3.871e-24	108.0	2AKRS@1|root,31BIM@2|Bacteria,1Q7DI@1224|Proteobacteria,2VDIH@28211|Alphaproteobacteria,47GC4@766|Rickettsiales	766|Rickettsiales	S	FliW protein	-	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
WLSH2_k127_971674_2	91604.ID47_04470	5.461e-97	323.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria,47F9W@766|Rickettsiales	766|Rickettsiales	P	Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system	znuC	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
WLSH2_k127_971674_5	244582.JQAK01000001_gene1266	7.743e-68	239.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,2TS2V@28211|Alphaproteobacteria,47FCW@766|Rickettsiales	766|Rickettsiales	P	ABC-type Mn2 Zn2 transport systems, permease components	znuB	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
WLSH2_k127_971674_6	91604.ID47_11440	3.419e-62	222.0	COG4649@1|root,COG4649@2|Bacteria,1Q3FF@1224|Proteobacteria,2U6ND@28211|Alphaproteobacteria,47FTH@766|Rickettsiales	766|Rickettsiales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
WLSH2_k127_971674_7	985867.AEWF01000002_gene1376	8.8e-59	206.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2U9JM@28211|Alphaproteobacteria,47FFR@766|Rickettsiales	766|Rickettsiales	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
WLSH2_k127_971674_8	247633.GP2143_07329	3.673e-50	195.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1JBK6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3344 Retron-type reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
WLSH2_k127_9723668_11	314285.KT71_05577	9.374e-10	59.0	COG3328@1|root,COG3328@2|Bacteria,1QE3H@1224|Proteobacteria,1TH70@1236|Gammaproteobacteria,1JA8W@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
WLSH2_k127_9723668_9	244582.JQAK01000001_gene874	2.181e-29	121.0	COG5425@1|root,COG5425@2|Bacteria,1N08I@1224|Proteobacteria,2UBVR@28211|Alphaproteobacteria,47FNI@766|Rickettsiales	766|Rickettsiales	E	Usg-like family	-	-	-	-	-	-	-	-	-	-	-	-	Usg
WLSH2_k127_9723668_3	244582.JQAK01000001_gene1511	3.388e-140	458.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2TWGV@28211|Alphaproteobacteria,47GTJ@766|Rickettsiales	766|Rickettsiales	G	COG0477 Permeases of the major facilitator superfamily	ampG4	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
WLSH2_k127_9723668_6	1458357.BG58_11775	1.304e-66	239.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
WLSH2_k127_9723668_7	244582.JQAK01000001_gene1259	7.76e-60	211.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,47FI1@766|Rickettsiales	766|Rickettsiales	C	Cytochrome C	cycM	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
WLSH2_k127_9723668_4	985867.AEWF01000002_gene1560	3.256e-79	271.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,47FAV@766|Rickettsiales	766|Rickettsiales	S	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
WLSH2_k127_9723668_10	244582.JQAK01000001_gene1365	1.335e-16	81.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_5
WLSH2_k127_9723668_2	159087.Daro_2117	1.289e-156	509.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,2KVF0@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WLSH2_k127_9723668_0	244582.JQAK01000001_gene1013	3.353e-189	595.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,47F15@766|Rickettsiales	766|Rickettsiales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WLSH2_k127_9723668_1	985867.AEWF01000001_gene2162	2.288e-186	587.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,47F1I@766|Rickettsiales	766|Rickettsiales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
WLSH2_k127_9723668_5	985867.AEWF01000001_gene2163	8.131e-70	245.0	COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,2UDVW@28211|Alphaproteobacteria,47FIQ@766|Rickettsiales	766|Rickettsiales	ET	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	yqiX	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WLSH2_k127_9775919_12	203122.Sde_1292	2.984e-75	271.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,464KG@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Secretion protein	lssD	-	-	ko:K02022,ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
WLSH2_k127_9775919_6	1198232.CYCME_0399	3.316e-163	538.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,45ZQX@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter transmembrane region	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
WLSH2_k127_9775919_10	985867.AEWF01000001_gene2073	1.264e-88	303.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2TV3E@28211|Alphaproteobacteria,47FIC@766|Rickettsiales	766|Rickettsiales	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
WLSH2_k127_9775919_14	1122169.AREN01000013_gene2261	2.236e-63	222.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,1S425@1236|Gammaproteobacteria,1JC54@118969|Legionellales	118969|Legionellales	O	Glutathione peroxidase	btuE	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WLSH2_k127_9775919_2	985867.AEWF01000002_gene1633	2.124e-198	625.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2TQXW@28211|Alphaproteobacteria,47F1X@766|Rickettsiales	766|Rickettsiales	I	PHB de-polymerase C-terminus	-	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
WLSH2_k127_9775919_28	1353528.DT23_02040	3.744e-09	63.0	COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria,2XNS3@285107|Thioclava	28211|Alphaproteobacteria	S	Protein of unknown function (DUF465)	MA20_03740	-	-	-	-	-	-	-	-	-	-	-	DUF465
WLSH2_k127_9775919_20	985867.AEWF01000003_gene911	2.852e-46	169.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,47FGB@766|Rickettsiales	766|Rickettsiales	FG	Protein kinase C inhibitor 1	pkcI	-	-	-	-	-	-	-	-	-	-	-	HIT
WLSH2_k127_9775919_9	985867.AEWF01000003_gene912	1.963e-89	297.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,47F57@766|Rickettsiales	766|Rickettsiales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
WLSH2_k127_9775919_0	985867.AEWF01000003_gene913	2.495e-225	704.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,47F04@766|Rickettsiales	766|Rickettsiales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
WLSH2_k127_9775919_17	985867.AEWF01000003_gene821	4.74e-58	203.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,47FHH@766|Rickettsiales	766|Rickettsiales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
WLSH2_k127_9775919_3	1122135.KB893168_gene1836	4.782e-198	623.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_9775919_8	227377.CBU_1877	6.545e-119	395.0	COG1373@1|root,COG1373@2|Bacteria,1RAB0@1224|Proteobacteria,1SA91@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_9775919_4	91604.ID47_00190	1.409e-182	576.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2TQJD@28211|Alphaproteobacteria,47EXG@766|Rickettsiales	766|Rickettsiales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
WLSH2_k127_9775919_5	985867.AEWF01000004_gene178	5.735e-173	547.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,47EX2@766|Rickettsiales	766|Rickettsiales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
WLSH2_k127_9775919_1	244582.JQAK01000001_gene1263	5.169e-224	705.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,47F09@766|Rickettsiales	766|Rickettsiales	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K13896	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
WLSH2_k127_9775919_22	244582.JQAK01000001_gene2143	4.913e-44	164.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2UC00@28211|Alphaproteobacteria,47FQ5@766|Rickettsiales	766|Rickettsiales	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WLSH2_k127_9775919_21	244582.JQAK01000001_gene1869	4.03e-45	171.0	COG4340@1|root,COG4340@2|Bacteria,1R9YQ@1224|Proteobacteria,2U65P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	2OG-Fe dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-Fe_Oxy_2
WLSH2_k127_9775919_19	244582.JQAK01000001_gene1869	2.002e-46	179.0	COG4340@1|root,COG4340@2|Bacteria,1R9YQ@1224|Proteobacteria,2U65P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	2OG-Fe dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-Fe_Oxy_2
WLSH2_k127_9775919_7	244582.JQAK01000001_gene1868	4.576e-154	494.0	COG0436@1|root,COG0436@2|Bacteria,1PEQR@1224|Proteobacteria,2V7WB@28211|Alphaproteobacteria,47GBS@766|Rickettsiales	766|Rickettsiales	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WLSH2_k127_9775919_23	357804.Ping_3724	2.684e-42	163.0	COG1296@1|root,COG1296@2|Bacteria,1MVGN@1224|Proteobacteria,1RZYJ@1236|Gammaproteobacteria,2QIEU@267894|Psychromonadaceae	1236|Gammaproteobacteria	E	AzlC protein	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
WLSH2_k127_9775919_30	1245471.PCA10_21120	8.033e-08	55.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,1SCKQ@1236|Gammaproteobacteria,1YGNV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
WLSH2_k127_9775919_32	1219035.NT2_08_01360	7.917e-07	52.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_9775919_25	1121124.JNIX01000008_gene2443	5.129e-32	132.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2UBY4@28211|Alphaproteobacteria,2KH4H@204458|Caulobacterales	204458|Caulobacterales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
WLSH2_k127_9775919_24	244582.JQAK01000001_gene1797	7.235e-42	166.0	COG2165@1|root,COG2165@2|Bacteria,1QVU6@1224|Proteobacteria,2UKPF@28211|Alphaproteobacteria,47FPK@766|Rickettsiales	766|Rickettsiales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9775919_18	985867.AEWF01000003_gene767	5.208e-56	203.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,47FEC@766|Rickettsiales	766|Rickettsiales	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WLSH2_k127_9775919_15	985867.AEWF01000003_gene766	4.123e-59	209.0	COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,47FJ2@766|Rickettsiales	766|Rickettsiales	S	protein conserved in bacteria	-	-	-	ko:K09985	-	-	-	-	ko00000	-	-	-	SspB
WLSH2_k127_9775919_31	1132836.RCCGE510_12016	2.775e-07	53.0	2A9UM@1|root,30Z2G@2|Bacteria,1PQIA@1224|Proteobacteria,2V2X8@28211|Alphaproteobacteria,4BJT2@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9775919_11	985867.AEWF01000002_gene1540	1.641e-77	276.0	COG0477@1|root,COG2814@2|Bacteria,1PE4X@1224|Proteobacteria,2V91X@28211|Alphaproteobacteria,47G2M@766|Rickettsiales	766|Rickettsiales	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
WLSH2_k127_9775919_16	293613.A1E_03375	4.712e-58	214.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U9SX@28211|Alphaproteobacteria,47FCZ@766|Rickettsiales	766|Rickettsiales	V	proteins, homologs of microcin C7 resistance protein MccF	mccF	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
WLSH2_k127_9775919_13	985867.AEWF01000001_gene1783	1.716e-69	248.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K11066	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
WLSH2_k127_9878474_0	91604.ID47_01865	6.193e-63	222.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,47FFZ@766|Rickettsiales	766|Rickettsiales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
## 1609 queries scanned
## Total time (seconds): 5.642725229263306
## Rate: 285.15 q/s