## Tue Dec 16 19:25:44 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WLSH2_bin.23.fa -m mmseqs --itype genome -o WLSH2_bin.23 --output_dir /data/result/bins/wyx/egg/WLSH2_bin.23 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WLSH2_k127_10007352_6	926569.ANT_08950	8.694e-19	91.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
WLSH2_k127_10007352_2	926569.ANT_16250	5.562e-42	171.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_16250|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10007352_0	926569.ANT_16230	5.612e-164	526.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi	200795|Chloroflexi	J	modification enzyme, MiaB family	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
WLSH2_k127_10007352_7	1121272.KB903292_gene3677	5.598e-18	92.0	COG2319@1|root,COG3428@1|root,COG2319@2|Bacteria,COG3428@2|Bacteria,2I79H@201174|Actinobacteria	201174|Actinobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
WLSH2_k127_10007352_1	163908.KB235896_gene4878	5.391e-149	484.0	COG3385@1|root,COG3385@2|Bacteria,1G2T1@1117|Cyanobacteria,1HMX0@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	ko:K07495	-	-	-	-	ko00000	-	-	-	DDE_5,DDE_Tnp_1
WLSH2_k127_10007352_3	1469607.KK073768_gene4767	1.322e-40	153.0	COG3744@1|root,COG3744@2|Bacteria,1G9VS@1117|Cyanobacteria,1HQ0Y@1161|Nostocales	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_10007352_8	373994.Riv7116_2000	5.052e-09	59.0	2BKR4@1|root,32F71@2|Bacteria,1GJZQ@1117|Cyanobacteria,1HSZ2@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10007352_5	926569.ANT_30440	5.508e-19	89.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WLSH2_k127_10034954_1	1089553.Tph_c21880	1.759e-65	236.0	COG0815@1|root,COG0815@2|Bacteria,1V095@1239|Firmicutes,24B2E@186801|Clostridia	186801|Clostridia	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WLSH2_k127_10034954_0	926550.CLDAP_20940	3.07e-130	423.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_10034954_2	926550.CLDAP_20930	1.353e-48	190.0	COG0842@1|root,COG0842@2|Bacteria	926550.CLDAP_20930|-	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
WLSH2_k127_10034954_3	1223523.H340_03194	1.764e-38	159.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
WLSH2_k127_10068544_14	926569.ANT_00370	2.435e-09	68.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH2_k127_10068544_10	926569.ANT_00360	1.584e-33	138.0	2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10068544_8	926569.ANT_00350	1.61e-53	197.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10068544_7	926569.ANT_12670	7.791e-62	215.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WLSH2_k127_10068544_3	926569.ANT_12660	2.181e-96	326.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
WLSH2_k127_10068544_1	926569.ANT_12630	6.246e-137	442.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WLSH2_k127_10068544_5	926569.ANT_12620	1.617e-90	305.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi	200795|Chloroflexi	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WLSH2_k127_10068544_13	383372.Rcas_3007	2.616e-11	74.0	COG0589@1|root,COG0589@2|Bacteria,2GBQ1@200795|Chloroflexi,375ZM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_10068544_11	999411.HMPREF1092_02129	3.82e-13	77.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,36IGJ@31979|Clostridiaceae	186801|Clostridia	P	Chromate transport protein	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WLSH2_k127_10068544_15	1243664.CAVL020000010_gene4530	2.931e-09	65.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,4HH2P@91061|Bacilli,1ZFWF@1386|Bacillus	91061|Bacilli	P	COG2059 Chromate transport protein ChrA	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WLSH2_k127_10068544_0	1385519.N801_16550	5.493e-141	457.0	COG3227@1|root,COG3227@2|Bacteria,2GN0P@201174|Actinobacteria,4FEV0@85021|Intrasporangiaceae	201174|Actinobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M36,Peptidase_M4_C
WLSH2_k127_10068544_4	926569.ANT_30970	4.543e-92	306.0	COG1838@1|root,COG1838@2|Bacteria,2G74D@200795|Chloroflexi	200795|Chloroflexi	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
WLSH2_k127_10068544_2	926569.ANT_30960	7.183e-128	416.0	COG1951@1|root,COG1951@2|Bacteria,2G6YI@200795|Chloroflexi	200795|Chloroflexi	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01676,ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
WLSH2_k127_10068544_9	742767.HMPREF9456_00665	5.924e-41	168.0	28MUJ@1|root,32ZXP@2|Bacteria,4P1S1@976|Bacteroidetes,2FWAP@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10068544_6	321332.CYB_0528	9.061e-86	301.0	COG2211@1|root,COG2211@2|Bacteria,1G0ZY@1117|Cyanobacteria,1GYSX@1129|Synechococcus	1117|Cyanobacteria	P	GPH family sugar transporter	melB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_1007842_14	574087.Acear_1201	2.841e-06	50.0	COG0697@1|root,COG0697@2|Bacteria,1TR1G@1239|Firmicutes,24DN8@186801|Clostridia,3WAPI@53433|Halanaerobiales	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_1007842_4	1118054.CAGW01000081_gene2691	1.957e-124	412.0	COG1679@1|root,COG1786@1|root,COG1679@2|Bacteria,COG1786@2|Bacteria,1UJDG@1239|Firmicutes,4HTS5@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
WLSH2_k127_1007842_10	570952.ATVH01000013_gene3075	4.361e-23	104.0	COG1786@1|root,COG1786@2|Bacteria,1NE20@1224|Proteobacteria,2VGP3@28211|Alphaproteobacteria,2JXB6@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function DUF126	-	-	-	-	-	-	-	-	-	-	-	-	DUF126
WLSH2_k127_1007842_6	1128421.JAGA01000002_gene796	1.462e-58	207.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WLSH2_k127_1007842_12	317013.NY99_19845	5.216e-15	85.0	COG4870@1|root,COG4870@2|Bacteria,1MYZH@1224|Proteobacteria	1224|Proteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Peptidase_C1,Peptidase_C1_2
WLSH2_k127_1007842_0	1521187.JPIM01000030_gene1508	1.068e-170	551.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
WLSH2_k127_1007842_3	1382356.JQMP01000004_gene276	1.985e-127	419.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,27XFC@189775|Thermomicrobia	189775|Thermomicrobia	H	Nucleotidyl transferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WLSH2_k127_1007842_1	926569.ANT_21040	9.97e-139	456.0	COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi	200795|Chloroflexi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WLSH2_k127_1007842_13	1265502.KB905930_gene1503	6.504e-09	67.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2VJ31@28216|Betaproteobacteria,4A9R4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_1007842_15	485913.Krac_1095	4.721e-05	48.0	2DRAK@1|root,33AYS@2|Bacteria	485913.Krac_1095|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1007842_2	91464.S7335_963	2.402e-138	472.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria	1117|Cyanobacteria	K	ATP-dependent transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
WLSH2_k127_1007842_11	1521187.JPIM01000149_gene405	1.61e-16	89.0	COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
WLSH2_k127_1007842_9	1487921.DP68_06660	3.923e-43	169.0	2ET8I@1|root,3147J@2|Bacteria,1USUA@1239|Firmicutes,24ZT1@186801|Clostridia,36QDI@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1007842_8	1536774.H70357_27195	2.169e-49	185.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_1007842_5	338963.Pcar_0523	5.656e-69	250.0	COG1835@1|root,COG1835@2|Bacteria,1MYXY@1224|Proteobacteria,42VFT@68525|delta/epsilon subdivisions,2WRGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WLSH2_k127_1007842_7	1499689.CCNN01000007_gene865	9.75e-52	188.0	COG1680@1|root,COG1680@2|Bacteria,1TRPT@1239|Firmicutes,2495H@186801|Clostridia,36WDR@31979|Clostridiaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Beta-lactamase,DUF302
WLSH2_k127_10083279_4	717606.PaecuDRAFT_4438	1.956e-63	224.0	COG0500@1|root,COG2226@2|Bacteria,1VR4R@1239|Firmicutes,4HUAS@91061|Bacilli,27563@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_10083279_7	1121324.CLIT_2c02360	7.577e-48	179.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_10083279_6	1382306.JNIM01000001_gene1923	8.794e-56	198.0	COG2606@1|root,COG2606@2|Bacteria,2G6MD@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
WLSH2_k127_10083279_8	32057.KB217478_gene5797	5.325e-37	145.0	COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria,1HP49@1161|Nostocales	1117|Cyanobacteria	S	phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
WLSH2_k127_10083279_1	1121382.JQKG01000026_gene2918	2.371e-190	599.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
WLSH2_k127_10083279_2	1337936.IJ00_01670	4.409e-123	414.0	COG1680@1|root,COG1680@2|Bacteria,1G5Z2@1117|Cyanobacteria,1HIVF@1161|Nostocales	1117|Cyanobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_10083279_3	358681.BBR47_40870	1.437e-86	295.0	COG0179@1|root,COG0179@2|Bacteria,1UY98@1239|Firmicutes,4HC89@91061|Bacilli,26UR6@186822|Paenibacillaceae	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
WLSH2_k127_10083279_9	246197.MXAN_3705	5.456e-07	59.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria,2YTYN@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
WLSH2_k127_10083279_0	324602.Caur_2513	2.28e-201	631.0	COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi,3766I@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM homogentisate 12-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
WLSH2_k127_10083279_5	118161.KB235922_gene5825	2.229e-62	218.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,3VJBK@52604|Pleurocapsales	1117|Cyanobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
WLSH2_k127_10086765_0	765420.OSCT_2993	7.628e-126	417.0	COG1290@1|root,COG1290@2|Bacteria,2G7XY@200795|Chloroflexi,377D3@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
WLSH2_k127_10086765_2	765420.OSCT_2253	5.31e-52	199.0	COG4902@1|root,COG4902@2|Bacteria,2G8V7@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein domain (DUF2202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
WLSH2_k127_10086765_3	765420.OSCT_2995	5.411e-50	186.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
WLSH2_k127_10086765_7	553218.CAMRE0001_2325	0.0007176	49.0	COG3303@1|root,COG3303@2|Bacteria,1QXPE@1224|Proteobacteria,42NA5@68525|delta/epsilon subdivisions,2YN2W@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
WLSH2_k127_10086765_4	744872.Spica_2810	2.379e-41	155.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WLSH2_k127_10086765_5	880073.Calab_3220	5.113e-27	113.0	COG0450@1|root,COG0450@2|Bacteria,2NQYA@2323|unclassified Bacteria	2|Bacteria	O	C-terminal domain of 1-Cys peroxiredoxin	prxU	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
WLSH2_k127_10086765_1	713586.KB900536_gene1627	4.194e-81	271.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	alkyl hydroperoxide reductase	ahpC	GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
WLSH2_k127_10086765_6	338963.Pcar_1581	3.442e-10	63.0	COG1433@1|root,COG1433@2|Bacteria,1N7IQ@1224|Proteobacteria,42WGA@68525|delta/epsilon subdivisions,2WS2U@28221|Deltaproteobacteria,43VG7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WLSH2_k127_10087373_13	926569.ANT_19760	1.123e-05	50.0	COG2267@1|root,COG2267@2|Bacteria,2G6KF@200795|Chloroflexi	200795|Chloroflexi	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
WLSH2_k127_10087373_6	1536772.R70723_27805	5.073e-47	175.0	COG0454@1|root,COG0456@2|Bacteria,1V81Z@1239|Firmicutes,4HIXF@91061|Bacilli,275IW@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
WLSH2_k127_10087373_1	926550.CLDAP_29000	4.538e-137	454.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi	200795|Chloroflexi	L	DNA photolyase domain protein	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
WLSH2_k127_10087373_2	926569.ANT_13490	4.828e-133	435.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
WLSH2_k127_10087373_9	316274.Haur_3982	1.18e-33	141.0	COG1028@1|root,COG1028@2|Bacteria,2G9VV@200795|Chloroflexi,377FY@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_10087373_8	293826.Amet_3778	9.116e-39	147.0	COG1225@1|root,COG1225@2|Bacteria,1VBNH@1239|Firmicutes,24QGI@186801|Clostridia	186801|Clostridia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_10087373_12	1402135.SUH3_01230	9.83e-07	56.0	2DMSH@1|root,32TDY@2|Bacteria,1N0AC@1224|Proteobacteria,2UDPH@28211|Alphaproteobacteria,3ZXZ8@60136|Sulfitobacter	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4345
WLSH2_k127_10087373_3	1115632.JAFW01000001_gene1315	2.5e-129	419.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WLSH2_k127_10087373_5	572479.Hprae_1208	2.877e-50	187.0	2AVV0@1|root,31215@2|Bacteria,1V4K5@1239|Firmicutes,251D8@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
WLSH2_k127_10087373_10	1499967.BAYZ01000048_gene2701	1.154e-32	134.0	2DMDR@1|root,32QSY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1475)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1475
WLSH2_k127_10087373_7	485913.Krac_8487	1.348e-46	181.0	COG1307@1|root,COG1307@2|Bacteria,2G6P2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH2_k127_10087373_4	926550.CLDAP_29050	3.577e-111	373.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WLSH2_k127_10087373_0	246197.MXAN_0895	2.458e-144	474.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,43BX1@68525|delta/epsilon subdivisions,2X77U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WLSH2_k127_10104521_1	671143.DAMO_2721	1.157e-17	86.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WLSH2_k127_10104521_0	94624.Bpet1057	4.2e-220	696.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VKHY@28216|Betaproteobacteria,3T90F@506|Alcaligenaceae	28216|Betaproteobacteria	LV	Retron-type reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
WLSH2_k127_10117858_13	1121377.KB906402_gene3232	5.135e-121	422.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
WLSH2_k127_10117858_37	861299.J421_0249	1.017e-38	168.0	COG3899@1|root,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,Pkinase
WLSH2_k127_10117858_22	269797.Mbar_A2861	6.651e-77	268.0	arCOG06785@1|root,arCOG06785@2157|Archaea	269797.Mbar_A2861|-	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10117858_6	269797.Mbar_A2862	1.484e-184	627.0	COG2319@1|root,arCOG02561@2157|Archaea,2Y41K@28890|Euryarchaeota,2NAYQ@224756|Methanomicrobia	224756|Methanomicrobia	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
WLSH2_k127_10117858_35	926550.CLDAP_28250	2.616e-43	163.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WLSH2_k127_10117858_34	926569.ANT_29070	1.147e-45	169.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_10117858_32	479434.Sthe_0178	1.033e-50	189.0	COG2267@1|root,COG2267@2|Bacteria,2G9QQ@200795|Chloroflexi,27ZAE@189775|Thermomicrobia	189775|Thermomicrobia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_10117858_24	555779.Dthio_PD3240	4.577e-68	239.0	COG3640@1|root,COG3640@2|Bacteria,1R819@1224|Proteobacteria,42PQR@68525|delta/epsilon subdivisions,2WKE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
WLSH2_k127_10117858_21	555079.Toce_0801	3.491e-77	266.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,42F6P@68295|Thermoanaerobacterales	186801|Clostridia	D	CO dehydrogenase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
WLSH2_k127_10117858_40	760568.Desku_1454	6.292e-23	107.0	COG1456@1|root,COG1456@2|Bacteria,1V556@1239|Firmicutes,24I6Z@186801|Clostridia,262FN@186807|Peptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
WLSH2_k127_10117858_2	909663.KI867150_gene97	6.221e-217	692.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
WLSH2_k127_10117858_0	555779.Dthio_PD3239	7.905e-271	853.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
WLSH2_k127_10117858_45	335543.Sfum_2679	1.455e-06	56.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	2.7.13.3,5.3.1.13	ko:K06041,ko:K11527	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01001,ko01005,ko02022	-	-	-	CBS,HATPase_c,HisKA
WLSH2_k127_10117858_17	903818.KI912268_gene1657	3.41e-94	318.0	COG2069@1|root,COG2069@2|Bacteria	2|Bacteria	C	one-carbon metabolic process	acsD	-	1.2.7.4,2.1.1.245	ko:K00194,ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R07157,R08034,R09096,R10219,R10243	RC00004,RC00113,RC00250,RC02800,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
WLSH2_k127_10117858_16	555779.Dthio_PD3225	8.453e-113	387.0	COG1456@1|root,COG1456@2|Bacteria,1R4RE@1224|Proteobacteria,42M89@68525|delta/epsilon subdivisions,2WJVQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
WLSH2_k127_10117858_11	429009.Adeg_0338	7.053e-157	516.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WLSH2_k127_10117858_31	555779.Dthio_PD3223	7.05e-52	196.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WIT3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase, DHPS	-	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WLSH2_k127_10117858_41	1236902.ANAS01000042_gene2248	2.332e-19	102.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
WLSH2_k127_10117858_23	161156.JQKW01000013_gene179	1.504e-71	260.0	COG0685@1|root,COG2069@1|root,COG0685@2|Bacteria,COG2069@2|Bacteria,2GHER@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CE	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
WLSH2_k127_10117858_36	1125863.JAFN01000001_gene3473	1.082e-40	157.0	COG1247@1|root,COG1247@2|Bacteria,1PBZE@1224|Proteobacteria,42VVQ@68525|delta/epsilon subdivisions,2WR9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_4
WLSH2_k127_10117858_44	760568.Desku_3119	5.396e-08	57.0	COG1150@1|root,COG1150@2|Bacteria,1V98Z@1239|Firmicutes,24JWG@186801|Clostridia,265DT@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_9
WLSH2_k127_10117858_5	1480694.DC28_13880	2.001e-196	623.0	COG0281@1|root,COG0281@2|Bacteria,2J5DN@203691|Spirochaetes	203691|Spirochaetes	C	Malic enzyme, NAD binding domain	mdh	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
WLSH2_k127_10117858_27	484770.UFO1_1504	8.603e-61	221.0	COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H46S@909932|Negativicutes	909932|Negativicutes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_10117858_29	65393.PCC7424_2961	1.739e-57	208.0	COG0730@1|root,COG0730@2|Bacteria,1G76Y@1117|Cyanobacteria,3KI6J@43988|Cyanothece	1117|Cyanobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WLSH2_k127_10117858_30	926569.ANT_11700	2.867e-57	206.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WLSH2_k127_10117858_43	926569.ANT_11690	2.841e-08	64.0	COG4698@1|root,COG4698@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2140
WLSH2_k127_10117858_12	926569.ANT_11680	2.059e-147	483.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
WLSH2_k127_10117858_10	926569.ANT_11670	4.816e-158	504.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WLSH2_k127_10117858_38	926569.ANT_11660	2.562e-35	143.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WLSH2_k127_10117858_33	926569.ANT_19700	9.682e-50	187.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH2_k127_10117858_25	1128421.JAGA01000002_gene981	1.7e-65	229.0	COG0652@1|root,COG0652@2|Bacteria,2NPSW@2323|unclassified Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
WLSH2_k127_10117858_19	926569.ANT_19710	1.014e-85	289.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WLSH2_k127_10117858_18	926569.ANT_22980	5.398e-87	295.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH2_k127_10117858_7	926569.ANT_09690	7.353e-166	528.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WLSH2_k127_10117858_20	926569.ANT_09700	2.262e-82	282.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi	200795|Chloroflexi	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WLSH2_k127_10117858_3	926569.ANT_09720	2.607e-216	694.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WLSH2_k127_10117858_28	926569.ANT_09730	3.063e-60	215.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi	200795|Chloroflexi	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
WLSH2_k127_10117858_15	926569.ANT_09740	2.261e-115	377.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
WLSH2_k127_10117858_42	469381.Dpep_1916	1.05e-17	89.0	COG0851@1|root,COG0851@2|Bacteria,3TBIQ@508458|Synergistetes	508458|Synergistetes	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
WLSH2_k127_10117858_14	926569.ANT_09760	5.853e-116	385.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WLSH2_k127_10117858_4	926569.ANT_09770	2.6e-211	666.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH2_k127_10117858_9	485913.Krac_3018	1.779e-163	534.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_10117858_8	211165.AJLN01000100_gene4070	8.174e-165	536.0	COG1132@1|root,COG1132@2|Bacteria,1G1QS@1117|Cyanobacteria,1JK9K@1189|Stigonemataceae	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_10117858_26	1121015.N789_13050	1.507e-63	224.0	COG2114@1|root,COG2114@2|Bacteria,1QTA2@1224|Proteobacteria,1S8ZW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WLSH2_k127_10117858_1	926569.ANT_01100	4.463e-256	799.0	COG0008@1|root,COG0008@2|Bacteria,2G827@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
WLSH2_k127_10200091_0	926569.ANT_09980	0.0	2056.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WLSH2_k127_10200091_1	926569.ANT_09990	1.137e-71	243.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi	200795|Chloroflexi	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
WLSH2_k127_10200091_2	926569.ANT_10000	3.846e-65	225.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
WLSH2_k127_10200091_3	1278073.MYSTI_04640	3.507e-14	72.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2YXGK@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH2_k127_10361607_5	926569.ANT_11050	2.318e-38	144.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WLSH2_k127_10361607_3	357808.RoseRS_0097	1.3e-105	351.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi,376IE@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_10361607_2	765420.OSCT_2981	1.632e-118	388.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,374VR@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
WLSH2_k127_10361607_0	880073.Calab_0927	8.218e-168	537.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WLSH2_k127_10361607_4	926569.ANT_26870	1.401e-84	290.0	COG1432@1|root,COG1432@2|Bacteria,2G7FS@200795|Chloroflexi	200795|Chloroflexi	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
WLSH2_k127_10361607_1	1122221.JHVI01000014_gene1367	4.781e-154	498.0	COG0665@1|root,COG0665@2|Bacteria,1WI96@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WLSH2_k127_10361607_7	485913.Krac_2962	3.361e-16	81.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
WLSH2_k127_10361607_6	485913.Krac_2962	1.838e-20	99.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
WLSH2_k127_10420825_0	1040986.ATYO01000012_gene5293	2.092e-195	660.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYI3@28211|Alphaproteobacteria,43RTK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,PAS_9,Response_reg
WLSH2_k127_10420825_3	426117.M446_1527	1.504e-35	138.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2UD5E@28211|Alphaproteobacteria,1JV34@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH2_k127_10420825_1	292563.Cyast_1767	4.182e-95	324.0	COG2208@1|root,COG2208@2|Bacteria,1G3MK@1117|Cyanobacteria	1117|Cyanobacteria	T	Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HisKA,Response_reg,SpoIIE
WLSH2_k127_10420825_2	880073.Calab_2236	3.758e-94	324.0	COG1373@1|root,COG1373@2|Bacteria,2NQPG@2323|unclassified Bacteria	2|Bacteria	S	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_1049646_1	926549.KI421517_gene4116	3.264e-121	393.0	COG0667@1|root,COG0667@2|Bacteria,4NEDK@976|Bacteroidetes,47KVC@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_1049646_2	926569.ANT_03150	5.157e-121	397.0	COG1208@1|root,COG1208@2|Bacteria,2G5KH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WLSH2_k127_1049646_0	357808.RoseRS_3240	1.802e-148	479.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,374TY@32061|Chloroflexia	32061|Chloroflexia	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_1049646_3	926550.CLDAP_02300	1.55e-34	151.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi	200795|Chloroflexi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1049646_4	926569.ANT_08190	3.6e-25	110.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WLSH2_k127_1049646_6	316274.Haur_4586	5.753e-07	52.0	COG0667@1|root,COG0667@2|Bacteria,2G7TU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_10624479_4	926569.ANT_12920	1.998e-86	299.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
WLSH2_k127_10624479_6	383372.Rcas_4163	5.831e-65	231.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WLSH2_k127_10624479_7	1172188.KB911822_gene707	2.014e-46	183.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
WLSH2_k127_10624479_3	251229.Chro_3485	2.518e-115	381.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,3VIUN@52604|Pleurocapsales	1117|Cyanobacteria	E	Zinc-binding dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
WLSH2_k127_10624479_2	926569.ANT_23190	3.349e-118	401.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WLSH2_k127_10624479_1	926569.ANT_23180	4.724e-132	432.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi	200795|Chloroflexi	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
WLSH2_k127_10624479_0	383372.Rcas_4054	7.341e-182	578.0	COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_10624479_5	867845.KI911784_gene269	1.134e-73	258.0	COG0454@1|root,COG0456@2|Bacteria,2G7M3@200795|Chloroflexi,377HI@32061|Chloroflexia	32061|Chloroflexia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10805234_6	926550.CLDAP_05920	2.141e-111	369.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WLSH2_k127_10805234_7	926550.CLDAP_05930	3.488e-93	310.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,cNMP_binding
WLSH2_k127_10805234_10	1121472.AQWN01000004_gene812	5.458e-49	178.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,2607X@186807|Peptococcaceae	186801|Clostridia	C	Molybdopterin oxidoreductase Fe4S4 region	-	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WLSH2_k127_10805234_2	555088.DealDRAFT_1821	3.068e-190	608.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,42JP3@68298|Syntrophomonadaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WLSH2_k127_10805234_1	1449126.JQKL01000004_gene565	4.326e-209	672.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,26AM4@186813|unclassified Clostridiales	186801|Clostridia	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WLSH2_k127_10805234_14	867845.KI911784_gene1274	2.743e-21	101.0	COG0457@1|root,COG0457@2|Bacteria	867845.KI911784_gene1274|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10805234_15	1410638.JHXJ01000001_gene1899	1.436e-18	92.0	COG2154@1|root,COG2154@2|Bacteria,1URUN@1239|Firmicutes,259S5@186801|Clostridia,3WQKI@541000|Ruminococcaceae	2|Bacteria	H	TIR domain	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a,TIR_2
WLSH2_k127_10805234_4	1049564.TevJSym_ac01750	1.454e-134	437.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1J5NQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
WLSH2_k127_10805234_8	1206733.BAGC01000107_gene6550	6.018e-71	247.0	29CZA@1|root,2ZZXB@2|Bacteria,2HH6P@201174|Actinobacteria,4FTY7@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10805234_0	903818.KI912268_gene2225	3.643e-304	960.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,3Y2VH@57723|Acidobacteria	57723|Acidobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	ko:K18930	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
WLSH2_k127_10805234_16	1499967.BAYZ01000073_gene2016	5.287e-09	59.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
WLSH2_k127_10805234_13	632245.CLP_3462	6.937e-27	119.0	COG0500@1|root,COG2226@2|Bacteria,1UI7M@1239|Firmicutes,24E0D@186801|Clostridia,36N6N@31979|Clostridiaceae	186801|Clostridia	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_10805234_11	1173024.KI912151_gene1817	1.149e-39	151.0	COG0221@1|root,COG0221@2|Bacteria,1GKG1@1117|Cyanobacteria,1JM4R@1189|Stigonemataceae	1117|Cyanobacteria	C	Inorganic pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Pyrophosphatase
WLSH2_k127_10805234_9	1128421.JAGA01000003_gene3490	5.595e-52	190.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
WLSH2_k127_10805234_12	1499967.BAYZ01000009_gene5260	6.543e-32	134.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10805234_3	383372.Rcas_2537	3.838e-158	527.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_10805234_5	357808.RoseRS_3212	8.528e-123	405.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
WLSH2_k127_10805234_17	658612.MD26_10790	6.563e-05	53.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,1RPV2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Secretion Protein	VVA0148	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH2_k127_10819985_12	196162.Noca_1631	3.675e-87	292.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4DV65@85009|Propionibacteriales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH2_k127_10819985_2	926569.ANT_01250	3.561e-165	524.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH2_k127_10819985_3	926569.ANT_01260	4.456e-154	491.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH2_k127_10819985_18	62928.azo3277	1.66e-10	71.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2VIB9@28216|Betaproteobacteria,2KU7E@206389|Rhodocyclales	206389|Rhodocyclales	G	polysaccharide deactylase family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
WLSH2_k127_10819985_14	525897.Dbac_2216	3.609e-46	181.0	COG3146@1|root,COG3146@2|Bacteria,1QYWX@1224|Proteobacteria,43CDR@68525|delta/epsilon subdivisions,2X7PP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM FemAB-related protein, PEP-CTERM	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WLSH2_k127_10819985_17	479434.Sthe_1147	5.988e-12	77.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	Acetyltransf_6
WLSH2_k127_10819985_15	1198452.Jab_1c03170	2.947e-27	121.0	COG4123@1|root,COG4123@2|Bacteria,1NCED@1224|Proteobacteria	1224|Proteobacteria	S	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH2_k127_10819985_16	370438.PTH_0126	9.598e-26	119.0	COG0392@1|root,COG0392@2|Bacteria,1VDGK@1239|Firmicutes,24Q29@186801|Clostridia,262MZ@186807|Peptococcaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH2_k127_10819985_6	765420.OSCT_2196	3.339e-140	458.0	COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi	200795|Chloroflexi	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
WLSH2_k127_10819985_4	272134.KB731324_gene1049	3.817e-152	496.0	COG3845@1|root,COG3845@2|Bacteria,1G4UA@1117|Cyanobacteria,1HH79@1150|Oscillatoriales	1117|Cyanobacteria	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WLSH2_k127_10819985_9	1125863.JAFN01000001_gene149	2.42e-99	335.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42MWE@68525|delta/epsilon subdivisions,2WKIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WLSH2_k127_10819985_10	1158318.ATXC01000001_gene666	8.376e-98	330.0	COG1079@1|root,COG1079@2|Bacteria	2|Bacteria	S	Belongs to the binding-protein-dependent transport system permease family	rbsC-2	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WLSH2_k127_10819985_11	913865.DOT_3610	6.308e-97	330.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,24DRF@186801|Clostridia,2646E@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WLSH2_k127_10819985_8	1313172.YM304_01540	1.984e-100	337.0	COG1079@1|root,COG1079@2|Bacteria,2GKMB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WLSH2_k127_10819985_7	1313172.YM304_01530	5.947e-109	363.0	COG1744@1|root,COG1744@2|Bacteria,2IEKS@201174|Actinobacteria	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
WLSH2_k127_10819985_1	1408254.T458_16090	1.019e-173	559.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli,26RES@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WLSH2_k127_10819985_13	926569.ANT_14800	1.688e-80	278.0	COG1319@1|root,COG1319@2|Bacteria,2G8QC@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
WLSH2_k127_10819985_19	926569.ANT_21570	5.131e-10	65.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_10819985_0	926569.ANT_14810	0.0	1210.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
WLSH2_k127_10819985_20	644107.SL1157_0208	1.893e-05	50.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2UBYM@28211|Alphaproteobacteria,4NC4G@97050|Ruegeria	28211|Alphaproteobacteria	S	Tol-pal system-associated acyl-CoA thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
WLSH2_k127_10849154_8	634956.Geoth_3676	3.526e-28	126.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,1WGI6@129337|Geobacillus	91061|Bacilli	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_10849154_11	292415.Tbd_2679	2.242e-06	59.0	COG1675@1|root,COG1675@2|Bacteria,1MZ5R@1224|Proteobacteria,2VV6V@28216|Betaproteobacteria	28216|Betaproteobacteria	K	transcription initiation from RNA polymerase II promoter	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10849154_13	218491.ECA3415	0.000455	49.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1S1T0@1236|Gammaproteobacteria,1MTE5@122277|Pectobacterium	1236|Gammaproteobacteria	L	integrase recombinase protein rsp0090 or rs05531 SWALL Q8XTL6 (EMBL AL646076) (347 aa) fasta scores E()	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
WLSH2_k127_10849154_12	329726.AM1_1305	9.244e-05	50.0	COG0568@1|root,COG0568@2|Bacteria,1G1HF@1117|Cyanobacteria	1117|Cyanobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH2_k127_10849154_2	926569.ANT_20520	2.122e-91	311.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WLSH2_k127_10849154_3	309799.DICTH_1813	1.292e-76	267.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH2_k127_10849154_4	398512.JQKC01000029_gene4330	6.205e-63	225.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,24B28@186801|Clostridia,3WI3W@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH2_k127_10849154_0	509191.AEDB02000065_gene705	2.28e-129	421.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,3WI32@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_10849154_5	743722.Sph21_1746	5.433e-55	199.0	COG1011@1|root,COG1011@2|Bacteria,4NIMR@976|Bacteroidetes,1IPZN@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
WLSH2_k127_10849154_1	383372.Rcas_1244	4.232e-95	318.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PA14,Phosphodiest
WLSH2_k127_10849154_9	696281.Desru_0494	3.935e-20	95.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,24HX6@186801|Clostridia,261GD@186807|Peptococcaceae	186801|Clostridia	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH2_k127_10849154_7	660470.Theba_2253	4.164e-32	139.0	28N4R@1|root,2ZBA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
WLSH2_k127_10849154_10	1536770.R50345_22615	2.96e-18	94.0	COG3385@1|root,COG3385@2|Bacteria,1VF22@1239|Firmicutes,4ITXA@91061|Bacilli,26YUE@186822|Paenibacillaceae	91061|Bacilli	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_10851652_13	696747.NIES39_B00100	2.291e-05	59.0	28I1A@1|root,2Z85Z@2|Bacteria,1G170@1117|Cyanobacteria,1H7KJ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10851652_14	521011.Mpal_0500	3.893e-05	56.0	COG2339@1|root,arCOG02985@2157|Archaea,2Y73S@28890|Euryarchaeota,2NB99@224756|Methanomicrobia	224756|Methanomicrobia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
WLSH2_k127_10851652_12	357808.RoseRS_1616	7.49e-07	60.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_C14,TPR_8
WLSH2_k127_10851652_2	395493.BegalDRAFT_3427	2.308e-89	301.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WLSH2_k127_10851652_9	1239962.C943_03877	1.131e-22	109.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
WLSH2_k127_10851652_3	456442.Mboo_1810	4.61e-73	263.0	arCOG06712@1|root,arCOG07605@1|root,arCOG06712@2157|Archaea,arCOG07605@2157|Archaea,2Y7KG@28890|Euryarchaeota	28890|Euryarchaeota	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
WLSH2_k127_10851652_4	269799.Gmet_1917	1.462e-51	194.0	COG2199@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2204@2|Bacteria,1QVAY@1224|Proteobacteria,42TG1@68525|delta/epsilon subdivisions,2WVCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response receiver sensor diguanylate cyclase, PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,Response_reg
WLSH2_k127_10851652_10	46234.ANA_C11282	9.509e-21	93.0	COG0286@1|root,COG0286@2|Bacteria,1G36A@1117|Cyanobacteria,1HMDZ@1161|Nostocales	1117|Cyanobacteria	V	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
WLSH2_k127_10851652_15	448385.sce1494	0.0005298	45.0	COG0515@1|root,COG0642@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1R72I@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,AAA_16,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_7,Pkinase
WLSH2_k127_10851652_6	215803.DB30_8412	1.024e-30	127.0	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1PEJF@1224|Proteobacteria,433Y5@68525|delta/epsilon subdivisions,2X2KM@28221|Deltaproteobacteria,2YXZ5@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
WLSH2_k127_10851652_1	697284.ERIC2_c09060	2.179e-113	375.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,26R39@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH2_k127_10851652_7	1391646.AVSU01000010_gene88	2.533e-27	127.0	COG0791@1|root,COG3807@1|root,COG0791@2|Bacteria,COG3807@2|Bacteria,1V9ZW@1239|Firmicutes,249UE@186801|Clostridia,25SRB@186804|Peptostreptococcaceae	186801|Clostridia	M	COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
WLSH2_k127_10851652_8	984262.SGRA_2270	1.163e-23	115.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	MA20_21840	-	3.2.1.96,3.5.1.28	ko:K01227,ko:K01448,ko:K03791,ko:K13277,ko:K17733	ko00511,ko01503,ko02024,map00511,map01503,map02024	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	GH19	-	Amidase_3,DUF1036,Glucosaminidase,PG_binding_1,SH3_3
WLSH2_k127_10851652_0	313624.NSP_34810	3.048e-229	728.0	COG1770@1|root,COG1770@2|Bacteria,1G1RH@1117|Cyanobacteria,1HJDI@1161|Nostocales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WLSH2_k127_10851652_5	1128421.JAGA01000003_gene3169	6.989e-51	188.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WLSH2_k127_10851652_11	697282.Mettu_0993	3.214e-10	61.0	COG3385@1|root,COG3385@2|Bacteria,1NIWM@1224|Proteobacteria,1S5FT@1236|Gammaproteobacteria,1XFX0@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_10854561_6	298655.KI912267_gene7354	6.74e-08	61.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
WLSH2_k127_10854561_0	926569.ANT_01730	6.532e-169	540.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH2_k127_10854561_1	198094.BA_1960	3.851e-97	327.0	2DB8K@1|root,2Z7S1@2|Bacteria,1TRA1@1239|Firmicutes,4HBIE@91061|Bacilli,1ZE40@1386|Bacillus	91061|Bacilli	G	Streptomycin adenylyltransferase	aadK	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
WLSH2_k127_10854561_3	926569.ANT_19030	2.558e-87	293.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
WLSH2_k127_10854561_4	926569.ANT_19040	1.148e-30	124.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10854561_2	926569.ANT_19050	1.033e-93	318.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,2G62P@200795|Chloroflexi	200795|Chloroflexi	L	HhH-GPD family	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
WLSH2_k127_10854561_5	1226322.HMPREF1545_03332	2.454e-22	100.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,2N6C1@216572|Oscillospiraceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
WLSH2_k127_10869974_10	632518.Calow_1305	5.473e-30	121.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,42ETC@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WLSH2_k127_10869974_6	926569.ANT_18960	3.405e-50	183.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WLSH2_k127_10869974_7	926569.ANT_18950	2.852e-46	169.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WLSH2_k127_10869974_4	926569.ANT_18940	8.172e-58	209.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi	200795|Chloroflexi	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WLSH2_k127_10869974_3	886293.Sinac_6174	2.957e-92	313.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WLSH2_k127_10869974_5	926569.ANT_03400	7.886e-53	202.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_10869974_8	926569.ANT_06720	4.833e-34	134.0	COG3877@1|root,COG3877@2|Bacteria,2G734@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
WLSH2_k127_10869974_11	926569.ANT_10390	1.054e-25	119.0	COG3595@1|root,COG3595@2|Bacteria,2G7DM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WLSH2_k127_10869974_1	926569.ANT_04390	1.69e-130	428.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
WLSH2_k127_10869974_9	926569.ANT_06730	1.565e-33	133.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10869974_0	1122222.AXWR01000002_gene2178	1.16e-130	430.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_10869974_2	457570.Nther_0397	5.295e-128	424.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,248MD@186801|Clostridia	186801|Clostridia	S	Modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH2_k127_10869974_13	313612.L8106_25460	1.907e-19	97.0	COG0312@1|root,COG0312@2|Bacteria,1G43A@1117|Cyanobacteria,1H9DT@1150|Oscillatoriales	1117|Cyanobacteria	S	and their inactivated homologs	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH2_k127_10922406_3	1340434.AXVA01000007_gene5144	1.14e-06	54.0	COG4655@1|root,COG4655@2|Bacteria,1V25X@1239|Firmicutes,4ITZ4@91061|Bacilli,1ZIQ4@1386|Bacillus	91061|Bacilli	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
WLSH2_k127_10922406_0	926569.ANT_16350	1.178e-298	925.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WLSH2_k127_10922406_2	867903.ThesuDRAFT_00034	1.114e-11	70.0	COG4961@1|root,COG4961@2|Bacteria,1VFNR@1239|Firmicutes,24R06@186801|Clostridia,3WDPM@538999|Clostridiales incertae sedis	186801|Clostridia	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
WLSH2_k127_10922406_1	1298880.AUEV01000028_gene4470	1.074e-12	79.0	COG3391@1|root,COG3391@2|Bacteria,2H4SV@201174|Actinobacteria	201174|Actinobacteria	MU	Bacterial Ig-like domain (group 3)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5
WLSH2_k127_11042384_0	138119.DSY2723	2.037e-124	419.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,2602R@186807|Peptococcaceae	186801|Clostridia	P	ATPase component of various ABC-type transport systems with duplicated ATPase domain	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WLSH2_k127_11042384_15	374847.Kcr_0337	1.605e-14	83.0	COG0619@1|root,arCOG02250@2157|Archaea	2157|Archaea	P	PFAM Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
WLSH2_k127_11042384_13	331869.BAL199_16123	5.237e-65	233.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2TSQB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
WLSH2_k127_11042384_1	1200792.AKYF01000010_gene2409	1.174e-123	414.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26R1I@186822|Paenibacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3,6.2.1.48	ko:K01897,ko:K02182,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_11042384_9	102129.Lepto7375DRAFT_8306	5.298e-78	273.0	COG3464@1|root,COG3464@2|Bacteria,1G42D@1117|Cyanobacteria,1HHEJ@1150|Oscillatoriales	1117|Cyanobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_11042384_4	479434.Sthe_2202	1.805e-104	359.0	COG0747@1|root,COG0747@2|Bacteria,2GA2M@200795|Chloroflexi,27YT9@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_11042384_3	1121091.AUMP01000064_gene3865	7.807e-108	368.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4H9T6@91061|Bacilli	91061|Bacilli	S	metal-dependent hydrolase with the TIM-barrel fold	ytcJ	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WLSH2_k127_11042384_2	479434.Sthe_2204	4.765e-108	359.0	COG0601@1|root,COG0601@2|Bacteria,2GBCN@200795|Chloroflexi,27YSV@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_11042384_5	309801.trd_1280	2.081e-103	343.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi,27Z1W@189775|Thermomicrobia	189775|Thermomicrobia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_11042384_14	1173027.Mic7113_1368	2.284e-42	181.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7HR@1150|Oscillatoriales	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,SpoIIE,TIR_2,WD40
WLSH2_k127_11042384_16	1123226.KB899279_gene2386	2.825e-09	65.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4HAQM@91061|Bacilli,26R44@186822|Paenibacillaceae	91061|Bacilli	U	Pilus assembly protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WLSH2_k127_11042384_17	1118054.CAGW01000061_gene2481	9.5e-08	59.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli,26QTS@186822|Paenibacillaceae	91061|Bacilli	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH2_k127_11042384_6	1094508.Tsac_2301	5.951e-100	338.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,248Q3@186801|Clostridia	186801|Clostridia	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
WLSH2_k127_11042384_11	1094508.Tsac_2300	6.605e-72	263.0	COG5297@1|root,COG5297@2|Bacteria,1UZ72@1239|Firmicutes,25DAV@186801|Clostridia,42HR5@68295|Thermoanaerobacterales	186801|Clostridia	G	Glycosyl hydrolase family 66	-	-	3.2.1.11	ko:K05988	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	Glyco_hydro_66
WLSH2_k127_11042384_10	1304865.JAGF01000001_gene1459	4.357e-77	267.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter (Permease)	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
WLSH2_k127_11042384_12	416591.Tlet_1227	9.532e-71	250.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10109,ko:K10118,ko:K15771,ko:K17242,ko:K17245	ko02010,map02010	M00194,M00196,M00198,M00207,M00491,M00600,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22,3.A.1.1.28,3.A.1.1.3,3.A.1.1.39,3.A.1.1.40	-	-	BPD_transp_1
WLSH2_k127_11042384_8	340099.Teth39_0261	3.668e-82	289.0	COG2182@1|root,COG2182@2|Bacteria,1UI3N@1239|Firmicutes,25F4S@186801|Clostridia,42I09@68295|Thermoanaerobacterales	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
WLSH2_k127_11042384_7	479435.Kfla_4053	9.429e-94	321.0	COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4DPVT@85009|Propionibacteriales	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
WLSH2_k127_11042384_18	395961.Cyan7425_2280	0.0007961	48.0	COG2433@1|root,COG2433@2|Bacteria,1G2BH@1117|Cyanobacteria	1117|Cyanobacteria	P	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
WLSH2_k127_11053733_2	1047013.AQSP01000134_gene1339	9.271e-39	149.0	COG5012@1|root,COG5012@2|Bacteria,2NQTJ@2323|unclassified Bacteria	2|Bacteria	S	B12 binding domain	-	-	-	ko:K14084	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124	RC00035,RC00732,RC02984	ko00000,ko00001,ko00002	-	-	-	B12-binding,B12-binding_2
WLSH2_k127_11053733_1	768706.Desor_4415	6.595e-42	171.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_11053733_0	589865.DaAHT2_2574	2.912e-48	191.0	COG5598@1|root,COG5598@2|Bacteria,1N18H@1224|Proteobacteria,42ME6@68525|delta/epsilon subdivisions,2WKDW@28221|Deltaproteobacteria,2MIBT@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_11053733_3	1304874.JAFY01000002_gene577	2.055e-28	121.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
WLSH2_k127_11085760_1	1121445.ATUZ01000018_gene2414	9.336e-24	106.0	2DPHF@1|root,33237@2|Bacteria,1R4GY@1224|Proteobacteria,435JT@68525|delta/epsilon subdivisions,2WZY2@28221|Deltaproteobacteria,2M8FU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
WLSH2_k127_11085760_0	768706.Desor_4320	2.057e-71	255.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,2642N@186807|Peptococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP pyruvate binding	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_11138088_6	926569.ANT_19480	1.244e-130	422.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WLSH2_k127_11138088_34	926569.ANT_19490	1.517e-56	201.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
WLSH2_k127_11138088_51	530564.Psta_3684	1.005e-16	82.0	COG1977@1|root,COG1977@2|Bacteria,2J1I1@203682|Planctomycetes	203682|Planctomycetes	H	COG1977 Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH2_k127_11138088_1	926550.CLDAP_06490	0.0	1050.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_11138088_24	926550.CLDAP_06500	1.727e-76	259.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WLSH2_k127_11138088_15	926550.CLDAP_06510	3.516e-100	334.0	COG1319@1|root,COG1319@2|Bacteria,2G8QI@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
WLSH2_k127_11138088_45	1229909.NSED_08400	1.151e-34	154.0	arCOG07561@1|root,arCOG07561@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3,VWA
WLSH2_k127_11138088_56	395495.Lcho_2202	0.0006186	51.0	COG4733@1|root,COG4733@2|Bacteria,1QZYI@1224|Proteobacteria,2VXAJ@28216|Betaproteobacteria,1KNYU@119065|unclassified Burkholderiales	2|Bacteria	S	PFAM Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PA14,fn3
WLSH2_k127_11138088_10	926550.CLDAP_06320	9.74e-128	416.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_11138088_55	1521187.JPIM01000077_gene1103	3.365e-06	58.0	COG1388@1|root,COG1388@2|Bacteria,2G99N@200795|Chloroflexi,375XT@32061|Chloroflexia	32061|Chloroflexia	M	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WLSH2_k127_11138088_11	243164.DET0573	2.779e-118	400.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WLSH2_k127_11138088_29	552811.Dehly_0557	1.504e-67	248.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
WLSH2_k127_11138088_12	926569.ANT_06790	1.751e-116	382.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
WLSH2_k127_11138088_19	926569.ANT_06780	4.183e-92	304.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
WLSH2_k127_11138088_8	926569.ANT_06770	4.752e-129	417.0	COG2267@1|root,COG2267@2|Bacteria,2G761@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_11138088_30	926569.ANT_03770	1.702e-60	216.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
WLSH2_k127_11138088_2	926569.ANT_06750	1.095e-186	593.0	COG1207@1|root,COG1207@2|Bacteria,2G7KV@200795|Chloroflexi	200795|Chloroflexi	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WLSH2_k127_11138088_13	429009.Adeg_1649	7.016e-115	380.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,42EPQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
WLSH2_k127_11138088_5	926569.ANT_06590	7.326e-138	443.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WLSH2_k127_11138088_0	926569.ANT_06600	0.0	1825.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WLSH2_k127_11138088_37	926569.ANT_06610	1.814e-49	178.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH2_k127_11138088_22	926569.ANT_06620	8.856e-81	276.0	COG0596@1|root,COG0596@2|Bacteria,2G8RI@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_11138088_40	926569.ANT_06690	3.144e-46	175.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Thiamin pyrophosphokinase, catalytic region	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
WLSH2_k127_11138088_4	926569.ANT_06700	1.72e-145	472.0	COG4143@1|root,COG4143@2|Bacteria,2G615@200795|Chloroflexi	200795|Chloroflexi	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
WLSH2_k127_11138088_3	926569.ANT_06710	4.465e-148	488.0	COG1178@1|root,COG1178@2|Bacteria,2G63A@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	BPD_transp_1
WLSH2_k127_11138088_16	926569.ANT_23590	1.185e-94	328.0	COG3842@1|root,COG3842@2|Bacteria,2G62Z@200795|Chloroflexi	200795|Chloroflexi	P	TOBE domain	-	-	3.6.3.31	ko:K02062,ko:K11072	ko02010,map02010	M00191,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1,3.A.1.19	-	-	ABC_tran,TOBE_2
WLSH2_k127_11138088_44	926569.ANT_23580	8.774e-35	138.0	COG3557@1|root,COG3557@2|Bacteria,2G79G@200795|Chloroflexi	200795|Chloroflexi	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
WLSH2_k127_11138088_31	926569.ANT_23560	1.092e-58	209.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
WLSH2_k127_11138088_38	926569.ANT_23520	4.167e-48	183.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WLSH2_k127_11138088_9	1121468.AUBR01000005_gene101	6.565e-129	421.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,42EQ1@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WLSH2_k127_11138088_18	926569.ANT_18930	4.689e-93	325.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	ftsZ	-	-	ko:K03531,ko:K03832	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko02048,ko03036,ko04812	2.C.1.1	-	-	DUF3747,DUF4173,FtsK_4TM,HAMP,HATPase_c,HisKA,TonB_C
WLSH2_k127_11138088_52	1333856.L686_11615	3.726e-11	68.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,1Z2WU@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH2_k127_11138088_39	379731.PST_1123	9.218e-47	188.0	COG3614@1|root,COG5002@1|root,COG3614@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RWNG@1236|Gammaproteobacteria,1Z02U@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_8,PAS_9,Response_reg
WLSH2_k127_11138088_7	419947.MRA_3417	6.113e-130	430.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria	201174|Actinobacteria	I	Squalene--hopene cyclase	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	5.5.1.16	ko:K17811	-	-	-	-	ko00000,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
WLSH2_k127_11138088_28	419947.MRA_3418	2.526e-69	248.0	28XHJ@1|root,2ZJEY@2|Bacteria	2|Bacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016101,GO:0016102,GO:0016114,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0035440,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0075136,GO:1901576	3.1.7.12,3.1.7.8,3.1.7.9	ko:K15911,ko:K22313	-	-	-	-	ko00000,ko01000	-	-	-	-
WLSH2_k127_11138088_53	1040989.AWZU01000051_gene998	2.363e-10	68.0	COG2020@1|root,COG2020@2|Bacteria,1MXP9@1224|Proteobacteria,2U2A4@28211|Alphaproteobacteria,3JV7T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
WLSH2_k127_11138088_54	292415.Tbd_0667	1.377e-06	60.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	bioF2	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Acetyltransf_6,FemAB_like
WLSH2_k127_11138088_43	1089547.KB913013_gene4388	2.259e-40	154.0	COG1661@1|root,COG1661@2|Bacteria,4NPS1@976|Bacteroidetes,47PS2@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
WLSH2_k127_11138088_35	383372.Rcas_2639	7.723e-55	210.0	COG0642@1|root,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS_4
WLSH2_k127_11138088_21	312284.A20C1_06196	3.348e-85	290.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,3UXBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
WLSH2_k127_11138088_17	1128421.JAGA01000001_gene2131	3.081e-94	317.0	COG1122@1|root,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WLSH2_k127_11138088_41	1449976.KALB_2006	3.053e-45	176.0	COG0619@1|root,COG0619@2|Bacteria,2HPW5@201174|Actinobacteria,4ECY2@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
WLSH2_k127_11138088_36	526222.Desal_3522	6.686e-50	187.0	COG3275@1|root,COG3275@2|Bacteria,1PY1H@1224|Proteobacteria,43EPZ@68525|delta/epsilon subdivisions,2X1BK@28221|Deltaproteobacteria,2MFQ8@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	-
WLSH2_k127_11138088_14	324602.Caur_0484	4.797e-104	347.0	COG1957@1|root,COG1957@2|Bacteria,2G6R6@200795|Chloroflexi,3766P@32061|Chloroflexia	32061|Chloroflexia	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
WLSH2_k127_11138088_20	1128421.JAGA01000001_gene2151	8.416e-86	295.0	COG1957@1|root,COG1957@2|Bacteria,2NPG1@2323|unclassified Bacteria	2|Bacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
WLSH2_k127_11138088_23	326427.Cagg_2909	2.96e-79	274.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi,376FG@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WLSH2_k127_11138088_42	383372.Rcas_0526	2.247e-43	177.0	COG2271@1|root,COG2271@2|Bacteria,2GBKS@200795|Chloroflexi,377QH@32061|Chloroflexia	32061|Chloroflexia	G	Nucleoside H+ symporter	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
WLSH2_k127_11138088_49	634956.Geoth_0831	3.625e-20	103.0	COG0477@1|root,COG2814@2|Bacteria,1TS3C@1239|Firmicutes,4HC3B@91061|Bacilli,1WEXZ@129337|Geobacillus	91061|Bacilli	EGP	Nucleoside H+ symporter	ywbF	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
WLSH2_k127_11138088_26	926569.ANT_17030	3.318e-72	256.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yicL_1	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
WLSH2_k127_11138088_32	243231.GSU1223	1.318e-57	211.0	29FVD@1|root,302T2@2|Bacteria,1RKWC@1224|Proteobacteria,42TAZ@68525|delta/epsilon subdivisions,2WP8E@28221|Deltaproteobacteria,43T6K@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11138088_47	357808.RoseRS_2161	3.08e-26	112.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
WLSH2_k127_11138088_46	269797.Mbar_A1687	8.659e-30	139.0	COG0642@1|root,arCOG02327@2157|Archaea,2XT8K@28890|Euryarchaeota,2NACV@224756|Methanomicrobia	224756|Methanomicrobia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_7TM,PAS
WLSH2_k127_11138088_25	118173.KB235914_gene3293	1.201e-74	284.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1G3MK@1117|Cyanobacteria,1H9X2@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Sporulation stage II, protein E C-terminal	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HAMP,SpoIIE
WLSH2_k127_11138088_50	326427.Cagg_2555	6.468e-18	100.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
WLSH2_k127_11138088_48	1220534.B655_1281	7.392e-21	95.0	COG1366@1|root,arCOG06891@2157|Archaea,2Y4H8@28890|Euryarchaeota	28890|Euryarchaeota	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
WLSH2_k127_11138088_27	1499967.BAYZ01000196_gene3072	2e-71	251.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	AAA_31,Patatin,cNMP_binding
WLSH2_k127_11138088_33	1499967.BAYZ01000196_gene3072	1.719e-57	210.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	AAA_31,Patatin,cNMP_binding
WLSH2_k127_11139620_3	477974.Daud_0108	1.611e-43	166.0	COG1810@1|root,COG1905@1|root,COG1810@2|Bacteria,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,261VF@186807|Peptococcaceae	186801|Clostridia	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WLSH2_k127_11139620_0	926569.ANT_27410	0.0	1303.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WLSH2_k127_11139620_2	1144275.COCOR_04256	3.026e-60	226.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11139620_1	997346.HMPREF9374_3675	5.278e-231	724.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,4HAPE@91061|Bacilli,27BM2@186824|Thermoactinomycetaceae	91061|Bacilli	E	Carboxypeptidase Taq (M32) metallopeptidase	ypwA	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
WLSH2_k127_11140696_0	485913.Krac_4778	2.118e-82	284.0	COG0667@1|root,COG0667@2|Bacteria,2G7TU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_11140696_1	171693.BN988_02365	4.804e-22	100.0	COG4242@1|root,COG4242@2|Bacteria,1V9TG@1239|Firmicutes,4IE2M@91061|Bacilli,23MYA@182709|Oceanobacillus	91061|Bacilli	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
WLSH2_k127_11162836_8	1122138.AQUZ01000030_gene4720	1.717e-87	303.0	COG2890@1|root,COG2890@2|Bacteria,2I3KM@201174|Actinobacteria,4DNZ4@85009|Propionibacteriales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
WLSH2_k127_11162836_20	377629.TERTU_1021	5.673e-26	111.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,2PNUS@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Translation initiation factor SUI1	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
WLSH2_k127_11162836_2	160799.PBOR_26510	1.047e-144	473.0	COG0076@1|root,COG0076@2|Bacteria,1TPVX@1239|Firmicutes,4HENF@91061|Bacilli	91061|Bacilli	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15,4.1.2.27	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	M00027,M00100	R00261,R00489,R01682,R02464,R02466,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
WLSH2_k127_11162836_18	471855.Shel_04870	8.694e-30	122.0	296T3@1|root,2ZU23@2|Bacteria,2HUYX@201174|Actinobacteria,4CW11@84998|Coriobacteriia	84998|Coriobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11162836_9	756499.Desde_2058	1.841e-79	274.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia	186801|Clostridia	C	nitroreductase	-	-	1.5.1.38	ko:K19285	ko00740,ko01100,map00740,map01100	-	R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
WLSH2_k127_11162836_11	443143.GM18_4304	7.966e-64	231.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
WLSH2_k127_11162836_7	589865.DaAHT2_0700	2.63e-107	367.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MPI2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
WLSH2_k127_11162836_10	1278307.KB906979_gene3753	8.856e-74	274.0	COG3291@1|root,COG4409@1|root,COG3291@2|Bacteria,COG4409@2|Bacteria,1NCV7@1224|Proteobacteria,1SDM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cleaves the terminal sialic acid (N-acetyl neuraminic acid) from carbohydrate chains in glycoproteins providing free sialic acid which can be used as carbon and energy sources. Sialidases have been suggested to be pathogenic factors in microbial infections. Facilitates cholera toxin binding to host intestinal epithelial cells by converting cell surface polysialogangliosides to GM1 monogangliosides	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3,PKD
WLSH2_k127_11162836_6	304371.MCP_1301	1.068e-110	377.0	arCOG09180@1|root,arCOG09180@2157|Archaea,2XTAJ@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
WLSH2_k127_11162836_4	304371.MCP_1300	4.677e-127	411.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_11162836_13	326427.Cagg_3772	1.771e-59	231.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
WLSH2_k127_11162836_1	448385.sce0611	1.306e-157	514.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42NXM@68525|delta/epsilon subdivisions,2WQMZ@28221|Deltaproteobacteria,2YY10@29|Myxococcales	28221|Deltaproteobacteria	C	Flavin containing amine oxidoreductase	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WLSH2_k127_11162836_15	118173.KB235910_gene4798	6.158e-43	160.0	2C4F3@1|root,32D38@2|Bacteria,1G6WA@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11162836_17	489825.LYNGBM3L_67230	2.932e-34	135.0	2CA6H@1|root,32RQP@2|Bacteria,1G86X@1117|Cyanobacteria,1HDCD@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WLSH2_k127_11162836_19	903818.KI912268_gene2350	1.006e-26	112.0	arCOG03368@1|root,331XD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11162836_12	926569.ANT_22980	1.191e-63	228.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH2_k127_11162836_0	357808.RoseRS_2964	1.712e-318	989.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2G7MP@200795|Chloroflexi,3760K@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	1.5.8.1,1.5.8.2	ko:K00317	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R01588,R02511	RC00185,RC00556,RC00557,RC00732	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
WLSH2_k127_11162836_16	926569.ANT_00450	5.867e-42	158.0	COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi	200795|Chloroflexi	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_5,LMWPc
WLSH2_k127_11162836_5	926569.ANT_02660	7.715e-112	367.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WLSH2_k127_11162836_3	926569.ANT_02650	1.854e-130	422.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi	2|Bacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_11162836_14	926569.ANT_02640	1.854e-45	166.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_11221783_3	933262.AXAM01000028_gene3342	3.651e-09	59.0	COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,42WFU@68525|delta/epsilon subdivisions,2WS4T@28221|Deltaproteobacteria,2MKX1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_11221783_0	497964.CfE428DRAFT_0631	1.652e-132	451.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
WLSH2_k127_11221783_4	706587.Desti_2082	2.004e-06	59.0	COG0500@1|root,COG2226@2|Bacteria,1PFBN@1224|Proteobacteria,42RZV@68525|delta/epsilon subdivisions,2WNGD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_11221783_1	1347368.HG964404_gene5394	1.02e-45	173.0	COG1413@1|root,COG1413@2|Bacteria,1VTQX@1239|Firmicutes,4HTH7@91061|Bacilli	91061|Bacilli	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11221783_2	91464.S7335_568	1.167e-26	119.0	COG1266@1|root,COG1266@2|Bacteria,1G9T4@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX amino terminal protease family	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_11267369_2	357808.RoseRS_2461	1.879e-56	201.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi	200795|Chloroflexi	F	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
WLSH2_k127_11267369_3	203119.Cthe_2213	2.09e-53	194.0	COG4843@1|root,COG4843@2|Bacteria,1V5RI@1239|Firmicutes,25DG5@186801|Clostridia	186801|Clostridia	S	UPF0316 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
WLSH2_k127_11267369_4	500633.CLOHIR_02218	6.192e-13	74.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,25TEH@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_11267369_1	765910.MARPU_00280	1.632e-108	366.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1WZAK@135613|Chromatiales	135613|Chromatiales	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
WLSH2_k127_11267369_0	926569.ANT_02680	6.14e-128	421.0	COG0475@1|root,COG0475@2|Bacteria,2G6B0@200795|Chloroflexi	200795|Chloroflexi	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WLSH2_k127_11267369_5	926569.ANT_02670	2.251e-09	59.0	COG0347@1|root,COG0347@2|Bacteria,2G9NA@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11274755_4	1120950.KB892707_gene4736	1.137e-14	87.0	2A5CY@1|root,30U2M@2|Bacteria,2GSI2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11274755_0	760192.Halhy_1321	1.742e-107	374.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1IVS2@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WLSH2_k127_11274755_1	765420.OSCT_0273	3.521e-101	341.0	COG0451@1|root,COG0451@2|Bacteria,2GAZF@200795|Chloroflexi,374ZI@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD
WLSH2_k127_11274755_6	591157.SSLG_06099	7.375e-10	66.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
WLSH2_k127_11274755_5	243274.THEMA_07785	3.13e-10	68.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
WLSH2_k127_11274755_3	102232.GLO73106DRAFT_00007210	5.09e-19	88.0	COG1598@1|root,COG1598@2|Bacteria,1G8YK@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
WLSH2_k127_11274755_7	420324.KI911996_gene8004	4.699e-09	59.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,1JTPR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM transposase IS4 family protein	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
WLSH2_k127_11274755_2	329726.AM1_1358	1.654e-29	119.0	COG3293@1|root,COG3293@2|Bacteria,1G0BW@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
WLSH2_k127_11287647_0	1386089.N865_01885	7.529e-129	419.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4FE57@85021|Intrasporangiaceae	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WLSH2_k127_11287647_1	272134.KB731324_gene3814	1.595e-82	280.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
WLSH2_k127_11407060_2	338969.Rfer_2518	9.274e-71	240.0	COG2519@1|root,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,2VHCQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
WLSH2_k127_11407060_1	1501230.ET33_07065	3.322e-72	258.0	COG2197@1|root,COG2197@2|Bacteria,1VSKR@1239|Firmicutes,4HUB6@91061|Bacilli,26WVV@186822|Paenibacillaceae	91061|Bacilli	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11407060_6	485913.Krac_0041	6.064e-25	111.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_11407060_4	694430.Natoc_3739	1.512e-49	188.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
WLSH2_k127_11407060_0	386456.JQKN01000003_gene298	6.931e-83	292.0	COG0001@1|root,arCOG00918@2157|Archaea,2XTRI@28890|Euryarchaeota,23NIZ@183925|Methanobacteria	183925|Methanobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_11407060_7	224325.AF_0578	3.178e-23	113.0	COG2234@1|root,arCOG02962@2157|Archaea	2157|Archaea	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WLSH2_k127_11407060_3	694430.Natoc_3739	6.123e-60	219.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
WLSH2_k127_11407060_5	1549858.MC45_01305	1.838e-25	115.0	COG1266@1|root,COG1266@2|Bacteria,1R5V2@1224|Proteobacteria,2U05S@28211|Alphaproteobacteria,2K3HV@204457|Sphingomonadales	204457|Sphingomonadales	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_11407733_4	926569.ANT_14570	1.818e-193	618.0	COG1111@1|root,COG1205@1|root,COG1403@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
WLSH2_k127_11407733_21	926569.ANT_12930	6.412e-86	295.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH2_k127_11407733_27	479434.Sthe_1388	1.81e-57	209.0	COG2738@1|root,COG2738@2|Bacteria,2G6KQ@200795|Chloroflexi,27YW2@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
WLSH2_k127_11407733_11	926569.ANT_12940	2.458e-120	400.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WLSH2_k127_11407733_35	357808.RoseRS_3213	4.609e-20	103.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8X1@200795|Chloroflexi,376YI@32061|Chloroflexia	32061|Chloroflexia	MV	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
WLSH2_k127_11407733_19	765420.OSCT_2139	3.19e-93	310.0	COG1136@1|root,COG1136@2|Bacteria,2G7XA@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_11407733_20	765420.OSCT_2138	3.128e-86	301.0	COG4591@1|root,COG4591@2|Bacteria,2G7ZF@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WLSH2_k127_11407733_13	765420.OSCT_2137	5.964e-116	387.0	COG4591@1|root,COG4591@2|Bacteria,2G85M@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WLSH2_k127_11407733_31	656519.Halsa_0289	1.093e-34	141.0	COG1309@1|root,COG1309@2|Bacteria,1V8M2@1239|Firmicutes,24J7T@186801|Clostridia,3WARX@53433|Halanaerobiales	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH2_k127_11407733_1	1116472.MGMO_104c00050	1.804e-269	873.0	COG2374@1|root,COG3210@1|root,COG3391@1|root,COG2374@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,1MX52@1224|Proteobacteria,1RMHH@1236|Gammaproteobacteria,1XG2B@135618|Methylococcales	135618|Methylococcales	U	Extracellular nuclease	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	-
WLSH2_k127_11407733_30	935866.JAER01000001_gene2712	3.701e-35	157.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF11,DUF4347
WLSH2_k127_11407733_12	926569.ANT_16990	1.709e-119	392.0	COG1052@1|root,COG1052@2|Bacteria,2G5K0@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_11407733_17	357808.RoseRS_1997	6.3e-103	353.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
WLSH2_k127_11407733_2	926569.ANT_01780	3.337e-238	740.0	COG1653@1|root,COG1653@2|Bacteria,2G5UT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117,ko:K17315	ko02010,map02010	M00196,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.28,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_11407733_8	926569.ANT_01790	4.251e-149	475.0	COG1175@1|root,COG1175@2|Bacteria,2G5W9@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
WLSH2_k127_11407733_9	926569.ANT_01800	5.402e-140	448.0	COG0395@1|root,COG0395@2|Bacteria,2G5SY@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
WLSH2_k127_11407733_37	326427.Cagg_3389	6.172e-09	61.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
WLSH2_k127_11407733_7	926569.ANT_01520	8.437e-181	571.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WLSH2_k127_11407733_34	1107311.Q767_04180	1.055e-21	102.0	COG3427@1|root,COG3427@2|Bacteria,4NQ8R@976|Bacteroidetes,1I3CY@117743|Flavobacteriia,2NW9C@237|Flavobacterium	976|Bacteroidetes	S	SRPBCC superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WLSH2_k127_11407733_33	1121015.N789_05975	7.805e-29	124.0	2DU7K@1|root,33P8K@2|Bacteria,1P4QZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11407733_18	255470.cbdbA1648	3.172e-96	330.0	2A40N@1|root,30SJ6@2|Bacteria,2G9WM@200795|Chloroflexi,34DKR@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11407733_38	706587.Desti_5217	1.792e-06	50.0	2C1SS@1|root,32YN6@2|Bacteria,1NNFV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11407733_36	756067.MicvaDRAFT_5356	1.353e-19	91.0	2E90H@1|root,3339X@2|Bacteria,1G9EW@1117|Cyanobacteria,1HDD6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11407733_24	1382306.JNIM01000001_gene514	5.119e-66	251.0	COG0515@1|root,COG0515@2|Bacteria,2G8NP@200795|Chloroflexi	200795|Chloroflexi	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DZR,Pkinase
WLSH2_k127_11407733_5	926569.ANT_00880	2.054e-193	626.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH2_k127_11407733_26	272134.KB731324_gene1337	1.662e-58	207.0	COG1670@1|root,COG1670@2|Bacteria,1G5GV@1117|Cyanobacteria,1HAQ0@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WLSH2_k127_11407733_14	926569.ANT_16300	6.527e-109	359.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
WLSH2_k127_11407733_22	1242864.D187_001151	2.225e-74	262.0	COG1181@1|root,COG1181@2|Bacteria,1Q3H4@1224|Proteobacteria,4399M@68525|delta/epsilon subdivisions,2X4H1@28221|Deltaproteobacteria,2YZ01@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WLSH2_k127_11407733_10	926569.ANT_08060	3.228e-133	434.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
WLSH2_k127_11407733_25	1173026.Glo7428_1028	1.676e-65	230.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WLSH2_k127_11407733_15	658086.HMPREF0994_03756	1.664e-106	361.0	COG1486@1|root,COG1486@2|Bacteria,1V6E5@1239|Firmicutes,24KU5@186801|Clostridia	186801|Clostridia	G	Family 4 glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
WLSH2_k127_11407733_28	926569.ANT_12960	1.34e-53	195.0	COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WLSH2_k127_11407733_3	926569.ANT_12970	1.655e-213	678.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WLSH2_k127_11407733_29	207559.Dde_3087	9.351e-43	164.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42PHT@68525|delta/epsilon subdivisions,2WKTH@28221|Deltaproteobacteria,2MCXW@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WLSH2_k127_11407733_0	926569.ANT_30670	1.48e-294	916.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WLSH2_k127_11407733_23	357808.RoseRS_2229	2.463e-69	261.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WLSH2_k127_11407733_6	926569.ANT_03160	2.704e-189	607.0	COG1164@1|root,COG1164@2|Bacteria,2G5SV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
WLSH2_k127_11407733_16	1267535.KB906767_gene4461	1.823e-104	342.0	COG0667@1|root,COG0667@2|Bacteria,3Y35T@57723|Acidobacteria,2JK73@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_1143072_7	880073.Calab_1283	1.346e-31	131.0	COG0438@1|root,COG0438@2|Bacteria,2NQHY@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1,Glycos_transf_2
WLSH2_k127_1143072_6	926560.KE387023_gene3532	1.578e-80	280.0	COG1609@1|root,COG1609@2|Bacteria,1WM4T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WLSH2_k127_1143072_2	1128421.JAGA01000003_gene2771	6.121e-152	493.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_1143072_5	1128421.JAGA01000003_gene2770	2.567e-90	306.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771,ko:K17312	ko02010,map02010	M00207,M00491,M00604	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.15,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WLSH2_k127_1143072_4	1128421.JAGA01000003_gene2769	8.686e-100	334.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH2_k127_1143072_3	926550.CLDAP_37870	7.006e-127	420.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	2|Bacteria	P	PFAM ABC transporter related	-	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
WLSH2_k127_1143072_1	518766.Rmar_1774	1.882e-168	540.0	COG1626@1|root,COG1626@2|Bacteria,4PKJT@976|Bacteroidetes	976|Bacteroidetes	G	glycoside hydrolase family 37	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
WLSH2_k127_1143072_0	926550.CLDAP_09870	8.665e-178	567.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
WLSH2_k127_11498020_13	1297569.MESS2_300088	1.394e-104	345.0	COG0604@1|root,COG0604@2|Bacteria,1MXIK@1224|Proteobacteria,2TQPR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	ccrA	-	1.1.1.1,1.3.1.85	ko:K00001,ko:K14446	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	M00373	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R09291	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_11498020_22	536019.Mesop_4490	2.71e-63	223.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2TQPP@28211|Alphaproteobacteria,43ITC@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
WLSH2_k127_11498020_8	859653.HIMB5_00004450	1.671e-124	409.0	COG0404@1|root,COG0404@2|Bacteria,1N705@1224|Proteobacteria,2TQT7@28211|Alphaproteobacteria,4BRBA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	2.1.1.269,2.1.2.10	ko:K00605,ko:K17486	ko00260,ko00630,ko00670,ko00920,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map00920,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125,R10333	RC00022,RC00069,RC00113,RC00183,RC00347,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C,SnoaL_2
WLSH2_k127_11498020_9	1282876.BAOK01000001_gene2669	3.411e-112	375.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,4BS41@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	MA20_17095	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_11498020_2	439493.PB7211_1299	1.056e-226	721.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQNH@28211|Alphaproteobacteria,4BPP0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	P	RecF/RecN/SMC N terminal domain	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WLSH2_k127_11498020_16	1042375.AFPL01000035_gene2852	2.388e-100	338.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,1RN08@1236|Gammaproteobacteria,46D4J@72275|Alteromonadaceae	1236|Gammaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WLSH2_k127_11498020_15	1042375.AFPL01000035_gene2851	2.37e-100	336.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,464TR@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	-	-	ko:K02033,ko:K15581,ko:K19227	ko01501,ko01503,ko02010,ko02024,map01501,map01503,map02010,map02024	M00239,M00439,M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25,3.A.1.5.5	-	-	BPD_transp_1
WLSH2_k127_11498020_12	488538.SAR116_0067	1.614e-107	369.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,4BQ8P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_11498020_23	335543.Sfum_3689	8.107e-59	212.0	COG1309@1|root,COG1309@2|Bacteria,1PFBP@1224|Proteobacteria,43A4U@68525|delta/epsilon subdivisions,2X2CD@28221|Deltaproteobacteria,2MSAM@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
WLSH2_k127_11498020_6	247633.GP2143_05635	5.014e-182	580.0	COG1053@1|root,COG1053@2|Bacteria,1QWW9@1224|Proteobacteria,1T3IG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
WLSH2_k127_11498020_19	313628.LNTAR_06699	8.533e-70	253.0	COG0492@1|root,COG2010@1|root,COG0492@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
WLSH2_k127_11498020_36	1499967.BAYZ01000036_gene2419	3.079e-06	51.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
WLSH2_k127_11498020_21	1128421.JAGA01000002_gene1765	1.231e-63	224.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
WLSH2_k127_11498020_24	292459.STH920	1.688e-57	214.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
WLSH2_k127_11498020_28	349161.Dred_1325	3.545e-41	160.0	COG1150@1|root,COG1150@2|Bacteria,1V6M0@1239|Firmicutes,24M4D@186801|Clostridia,26709@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
WLSH2_k127_11498020_14	1121422.AUMW01000010_gene1060	2.243e-100	337.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,260T4@186807|Peptococcaceae	186801|Clostridia	C	heterodisulfide reductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
WLSH2_k127_11498020_0	1121423.JONT01000001_gene1843	0.0	1451.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
WLSH2_k127_11498020_20	1125863.JAFN01000001_gene1777	1.347e-65	226.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria,42TFE@68525|delta/epsilon subdivisions,2WPDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
WLSH2_k127_11498020_18	868595.Desca_0819	6.154e-77	271.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_8,FrhB_FdhB_C
WLSH2_k127_11498020_1	335543.Sfum_0824	5.092e-260	829.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,2MQTQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K15022	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00356,M00357,M00377,M00563,M00567	R00134,R04540,R11928,R11931,R11943,R11944	RC00011,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
WLSH2_k127_11498020_10	1125863.JAFN01000001_gene2931	3.555e-111	372.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8,Fer4_9,Nitrate_red_gam
WLSH2_k127_11498020_7	386456.JQKN01000010_gene695	1.543e-162	531.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23NUK@183925|Methanobacteria	183925|Methanobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
WLSH2_k127_11498020_31	696281.Desru_2695	1.015e-31	137.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_8,FrhB_FdhB_C
WLSH2_k127_11498020_32	706587.Desti_4515	9.068e-26	111.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_22,Fer4_8,FrhB_FdhB_C
WLSH2_k127_11498020_17	1121468.AUBR01000048_gene1645	1.681e-80	274.0	COG1152@1|root,COG1152@2|Bacteria,1UKJG@1239|Firmicutes,25FYP@186801|Clostridia	186801|Clostridia	C	PFAM Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_10,Fer4_9
WLSH2_k127_11498020_26	345219.Bcoa_0729	1.209e-44	176.0	COG1960@1|root,COG1960@2|Bacteria,1UZKG@1239|Firmicutes,4HA6B@91061|Bacilli,1ZEAS@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_11498020_29	868595.Desca_0819	6.879e-36	150.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_8,FrhB_FdhB_C
WLSH2_k127_11498020_4	1121430.JMLG01000005_gene675	3.798e-212	672.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,264B9@186807|Peptococcaceae	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
WLSH2_k127_11498020_25	1041930.Mtc_2332	3.576e-45	171.0	COG1394@1|root,arCOG04101@2157|Archaea,2Y394@28890|Euryarchaeota,2NA8W@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD-2	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WLSH2_k127_11498020_5	323259.Mhun_1758	4.83e-190	605.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WLSH2_k127_11498020_3	523845.AQXV01000049_gene939	4.724e-218	691.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,23Q05@183939|Methanococci	183939|Methanococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
WLSH2_k127_11498020_35	42256.RradSPS_2938	1.734e-06	56.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
WLSH2_k127_11498020_30	323259.Mhun_1761	1.596e-32	140.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota	28890|Euryarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC-2	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
WLSH2_k127_11498020_33	323259.Mhun_1762	8.773e-19	94.0	COG1390@1|root,arCOG00869@2157|Archaea	2157|Archaea	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
WLSH2_k127_11498020_34	593750.Metfor_0254	7.844e-14	74.0	COG0636@1|root,arCOG02455@2157|Archaea,2Y4F6@28890|Euryarchaeota,2NB8I@224756|Methanomicrobia	224756|Methanomicrobia	C	ATP synthase subunit C	atpK-2	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
WLSH2_k127_11498020_11	1041930.Mtc_1283	1.103e-109	378.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,2NAKS@224756|Methanomicrobia	224756|Methanomicrobia	C	V-type ATPase 116kDa subunit family	atpI-2	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
WLSH2_k127_11498020_27	926569.ANT_26560	3.916e-42	158.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi	200795|Chloroflexi	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_1321689_3	584708.Apau_2248	2.093e-12	68.0	COG0745@1|root,COG0745@2|Bacteria,3TAJR@508458|Synergistetes	508458|Synergistetes	K	PFAM response regulator receiver	-	-	-	ko:K07657,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_1321689_0	662479.C440_17076	1.175e-26	118.0	arCOG06181@1|root,arCOG06181@2157|Archaea,2Y06C@28890|Euryarchaeota,23XFD@183963|Halobacteria	183963|Halobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1321689_1	1114856.C496_20690	3.935e-26	117.0	arCOG02399@1|root,arCOG02399@2157|Archaea,2XVVI@28890|Euryarchaeota,23UYC@183963|Halobacteria	183963|Halobacteria	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WLSH2_k127_1321689_2	159087.Daro_3750	3.162e-13	71.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WGZJ@28216|Betaproteobacteria,2KVQZ@206389|Rhodocyclales	206389|Rhodocyclales	T	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_4
WLSH2_k127_135225_3	713587.THITH_10820	9.068e-26	111.0	COG0450@1|root,COG0450@2|Bacteria,1NBK9@1224|Proteobacteria	1224|Proteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_135225_1	1255043.TVNIR_1207	6.311e-82	273.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	alkyl hydroperoxide reductase	ahpC	GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
WLSH2_k127_135225_5	56780.SYN_01171	4.607e-12	72.0	COG1433@1|root,COG1433@2|Bacteria,1N7IQ@1224|Proteobacteria,42WGA@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WLSH2_k127_135225_4	429009.Adeg_1087	5.73e-25	108.0	COG1433@1|root,COG1433@2|Bacteria,1VFDZ@1239|Firmicutes,24R8N@186801|Clostridia,42GPN@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WLSH2_k127_135225_0	765911.Thivi_0862	6.598e-98	327.0	COG1149@1|root,COG1149@2|Bacteria,1NCD9@1224|Proteobacteria,1RZVT@1236|Gammaproteobacteria,1WX11@135613|Chromatiales	135613|Chromatiales	C	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
WLSH2_k127_135225_2	765911.Thivi_0863	1.644e-43	161.0	COG1149@1|root,COG1149@2|Bacteria,1MVPB@1224|Proteobacteria,1RRMS@1236|Gammaproteobacteria,1WXFM@135613|Chromatiales	135613|Chromatiales	C	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
WLSH2_k127_1404552_1	768671.ThimaDRAFT_4426	2.104e-185	595.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria,1SQA0@1236|Gammaproteobacteria,1X16W@135613|Chromatiales	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1404552_7	926569.ANT_03750	6.923e-91	310.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	ssuA	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
WLSH2_k127_1404552_6	926569.ANT_03740	2.369e-92	309.0	COG1116@1|root,COG1116@2|Bacteria,2G8SU@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
WLSH2_k127_1404552_5	926569.ANT_03730	5.298e-96	319.0	COG0600@1|root,COG0600@2|Bacteria,2G72A@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
WLSH2_k127_1404552_4	349161.Dred_2781	1.491e-99	332.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,26573@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WLSH2_k127_1404552_8	926569.ANT_24730	1.51e-75	260.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi	200795|Chloroflexi	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
WLSH2_k127_1404552_3	1122223.KB890687_gene2749	3.11e-150	492.0	COG3345@1|root,COG3345@2|Bacteria,1WIV5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
WLSH2_k127_1404552_2	926560.KE387027_gene866	2.235e-153	502.0	COG3345@1|root,COG3345@2|Bacteria,1WIV5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
WLSH2_k127_1404552_0	926569.ANT_22850	0.0	1598.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WLSH2_k127_1404552_9	414684.RC1_1051	1.491e-36	147.0	COG1183@1|root,COG1183@2|Bacteria,1NGCJ@1224|Proteobacteria,2TS1K@28211|Alphaproteobacteria,2JSRI@204441|Rhodospirillales	204441|Rhodospirillales	I	Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP	-	-	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	-
WLSH2_k127_1404552_10	1121912.AUHD01000007_gene504	1.426e-24	108.0	COG0454@1|root,COG0456@2|Bacteria,4NSH4@976|Bacteroidetes,1I419@117743|Flavobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) family	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
WLSH2_k127_1427940_1	663278.Ethha_0113	1.165e-26	114.0	2ERRQ@1|root,33JAW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1427940_3	748247.AZKH_0320	1.602e-06	60.0	COG3292@1|root,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,2VPDV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
WLSH2_k127_1427940_4	13616.ENSMODP00000019006	5.176e-06	57.0	KOG4475@1|root,KOG4475@2759|Eukaryota,39TF4@33154|Opisthokonta,3BEDR@33208|Metazoa,3D3US@33213|Bilateria,489BI@7711|Chordata,494KD@7742|Vertebrata,3J6QJ@40674|Mammalia,4K7BY@9263|Metatheria	33208|Metazoa	P	Von Willebrand factor A domain containing 7	VWA7	-	-	-	-	-	-	-	-	-	-	-	VWA_2
WLSH2_k127_1427940_0	926569.ANT_11280	1.047e-57	207.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
WLSH2_k127_1442868_7	945713.IALB_1235	3.433e-21	98.0	28J1N@1|root,2Z8YI@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WLSH2_k127_1442868_6	869213.JCM21142_104490	1.959e-34	142.0	28KWY@1|root,2ZAD1@2|Bacteria,4NM1H@976|Bacteroidetes,47SKN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1442868_9	326427.Cagg_2222	1.288e-05	48.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,375BH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
WLSH2_k127_1442868_3	552811.Dehly_1213	1.079e-63	235.0	COG2211@1|root,COG2211@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1442868_8	1499967.BAYZ01000041_gene2389	3.707e-06	57.0	COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria	2|Bacteria	I	Phosphate acyltransferases	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH2_k127_1442868_1	383372.Rcas_0084	7.816e-162	518.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_1442868_5	926569.ANT_17460	4.827e-46	183.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10117,ko:K17318	ko02010,map02010	M00196,M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_1442868_2	926569.ANT_27830	2.903e-102	346.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WLSH2_k127_1442868_4	926569.ANT_06830	9.982e-62	218.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
WLSH2_k127_1442868_0	926569.ANT_06840	7.117e-179	571.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi	200795|Chloroflexi	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WLSH2_k127_1456784_1	794903.OPIT5_14440	7.555e-178	570.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,3K78R@414999|Opitutae	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WLSH2_k127_1456784_5	382464.ABSI01000010_gene3730	3.002e-29	123.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
WLSH2_k127_1456784_4	926569.ANT_07800	3.864e-42	162.0	COG1437@1|root,COG1437@2|Bacteria,2G9FW@200795|Chloroflexi	200795|Chloroflexi	F	CYTH domain	-	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
WLSH2_k127_1456784_8	1068978.AMETH_3302	1.304e-10	73.0	COG4632@1|root,COG4632@2|Bacteria,2GNTM@201174|Actinobacteria	201174|Actinobacteria	G	Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA,SPOR
WLSH2_k127_1456784_2	926569.ANT_04470	2.073e-155	499.0	COG3227@1|root,COG3227@2|Bacteria,2G6Q0@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M4 thermolysin	-	-	3.4.24.27	ko:K08603	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	FTP,PLN_propep,Peptidase_M4,Peptidase_M4_C
WLSH2_k127_1456784_7	1123053.AUDG01000035_gene746	2.209e-21	109.0	COG3757@1|root,COG3757@2|Bacteria,1N792@1224|Proteobacteria,1SC72@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	lysozyme activity	yegX	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
WLSH2_k127_1456784_6	1121090.KB894702_gene1246	1.731e-22	113.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1V3MD@1239|Firmicutes,4HHD1@91061|Bacilli,1ZBPF@1386|Bacillus	91061|Bacilli	M	n-acetylmuramoyl-L-alanine amidase	cwlC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,PG_binding_1,SPOR
WLSH2_k127_1456784_3	926569.ANT_19880	1.337e-138	448.0	COG0809@1|root,COG0809@2|Bacteria,2G5UZ@200795|Chloroflexi	200795|Chloroflexi	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WLSH2_k127_1456784_0	926569.ANT_02850	2.407e-180	576.0	COG1236@1|root,COG1236@2|Bacteria,2G62G@200795|Chloroflexi	200795|Chloroflexi	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
WLSH2_k127_1456784_10	572544.Ilyop_1609	3.975e-07	53.0	2EYYJ@1|root,33S5A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1467536_1	926569.ANT_28790	3.63e-62	215.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
WLSH2_k127_1467536_0	56780.SYN_02685	1.871e-152	491.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2WJB1@28221|Deltaproteobacteria,2MR6Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH2_k127_1475402_5	1385519.N801_03195	7.75e-98	323.0	COG2234@1|root,COG2234@2|Bacteria,2IDP0@201174|Actinobacteria,4FE57@85021|Intrasporangiaceae	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WLSH2_k127_1475402_4	926560.KE387027_gene366	1.86e-114	385.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_1475402_15	395495.Lcho_3668	0.0001945	52.0	COG4733@1|root,COG4733@2|Bacteria,1QZYI@1224|Proteobacteria,2VXAJ@28216|Betaproteobacteria,1KNYU@119065|unclassified Burkholderiales	2|Bacteria	S	PFAM Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Malectin,PA14,fn3
WLSH2_k127_1475402_0	926569.ANT_15490	3.083e-284	884.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WLSH2_k127_1475402_10	330214.NIDE4175	3.811e-46	186.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
WLSH2_k127_1475402_14	1408304.JAHA01000007_gene1436	5.26e-12	79.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Lectin_legB,PQQ,PQQ_2,Peptidase_C14,TIR_2,WD40
WLSH2_k127_1475402_9	66875.JODY01000023_gene5676	3.933e-65	248.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_1475402_11	216594.MMAR_5214	6.17e-22	101.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,234M5@1762|Mycobacteriaceae	201174|Actinobacteria	S	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
WLSH2_k127_1475402_13	330214.NIDE1115	9.057e-15	82.0	COG0265@1|root,COG1262@1|root,COG0265@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Trypsin_2
WLSH2_k127_1475402_3	485913.Krac_11734	1.14e-139	462.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH2_k127_1475402_6	926569.ANT_17240	3.735e-94	325.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
WLSH2_k127_1475402_7	926550.CLDAP_16000	1.529e-88	304.0	COG0500@1|root,COG2226@2|Bacteria,2G7XP@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_1475402_2	448385.sce7039	1.393e-201	642.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YX8I@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
WLSH2_k127_1475402_1	324602.Caur_3096	4.41e-280	899.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi,375DR@32061|Chloroflexia	32061|Chloroflexia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH2_k127_1475402_8	926569.ANT_20430	1.657e-67	234.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WLSH2_k127_1475402_12	926569.ANT_20440	8.67e-15	82.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_14880_1	395961.Cyan7425_1515	6.415e-54	199.0	COG0726@1|root,COG0726@2|Bacteria,1G02J@1117|Cyanobacteria,3KI1Q@43988|Cyanothece	1117|Cyanobacteria	G	PFAM polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WLSH2_k127_14880_0	649638.Trad_0250	3.076e-64	226.0	COG2258@1|root,COG2258@2|Bacteria,1WMGC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
WLSH2_k127_14880_2	1519464.HY22_05255	7.978e-47	176.0	2ETC6@1|root,33KW3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_14880_3	305900.GV64_07175	5.296e-08	59.0	COG5649@1|root,COG5649@2|Bacteria,1ND08@1224|Proteobacteria,1SF0X@1236|Gammaproteobacteria,1XQ1Z@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WLSH2_k127_150480_2	373994.Riv7116_1807	1.079e-63	231.0	COG0596@1|root,COG0596@2|Bacteria,1GJMM@1117|Cyanobacteria,1HSGW@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_150480_5	118161.KB235922_gene2311	2.635e-12	73.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WLSH2_k127_150480_3	1037409.BJ6T_09450	8.279e-26	120.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,3JSZR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
WLSH2_k127_150480_1	1536774.H70357_34270	3.177e-79	284.0	COG1680@1|root,COG1680@2|Bacteria,1UZZ5@1239|Firmicutes,4HA1I@91061|Bacilli,26XEG@186822|Paenibacillaceae	91061|Bacilli	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
WLSH2_k127_150480_0	1122221.JHVI01000003_gene389	2.807e-122	424.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Pkinase,TPR_10,TPR_12,Trans_reg_C
WLSH2_k127_1506879_42	748727.CLJU_c17830	9.84e-05	52.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia,36GY4@31979|Clostridiaceae	186801|Clostridia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WLSH2_k127_1506879_11	926569.ANT_20980	5.982e-109	359.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
WLSH2_k127_1506879_15	926569.ANT_20970	3.137e-97	325.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K09820,ko:K11710	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
WLSH2_k127_1506879_24	1128421.JAGA01000003_gene3096	5.992e-66	235.0	COG0803@1|root,COG0803@2|Bacteria,2NP5U@2323|unclassified Bacteria	2|Bacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077,ko:K09818	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
WLSH2_k127_1506879_30	1123288.SOV_5c01990	6.199e-42	168.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4H234@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WLSH2_k127_1506879_41	324602.Caur_1061	3.064e-05	52.0	COG1366@1|root,COG1366@2|Bacteria,2G9DJ@200795|Chloroflexi,375QD@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS_2
WLSH2_k127_1506879_19	926569.ANT_14560	2.464e-84	294.0	COG0790@1|root,COG3359@1|root,COG0790@2|Bacteria,COG3359@2|Bacteria,2G6TK@200795|Chloroflexi	200795|Chloroflexi	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
WLSH2_k127_1506879_17	1120998.AUFC01000002_gene2638	3.295e-90	331.0	COG3210@1|root,COG4677@1|root,COG3210@2|Bacteria,COG4677@2|Bacteria,1TR9M@1239|Firmicutes,24BEI@186801|Clostridia	186801|Clostridia	U	S-layer domain-containing protein	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Flg_new,SLH
WLSH2_k127_1506879_31	926569.ANT_08030	2.871e-38	166.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WLSH2_k127_1506879_18	1170562.Cal6303_4741	7.326e-88	309.0	COG2211@1|root,COG2211@2|Bacteria,1G0ZY@1117|Cyanobacteria	1117|Cyanobacteria	G	COG2211 Na melibiose symporter and related	melB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_1506879_5	926569.ANT_03590	2.67e-188	617.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
WLSH2_k127_1506879_6	1121481.AUAS01000005_gene2121	1.243e-165	528.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,47N6I@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WLSH2_k127_1506879_0	926569.ANT_22270	1.371e-314	974.0	COG0153@1|root,COG1210@1|root,COG0153@2|Bacteria,COG1210@2|Bacteria,2G6XV@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WLSH2_k127_1506879_1	926550.CLDAP_17180	1.591e-230	719.0	COG2873@1|root,COG2873@2|Bacteria,2G5NS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	CoA_binding_2,Cys_Met_Meta_PP
WLSH2_k127_1506879_9	203119.Cthe_1845	2.034e-138	447.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,HTS
WLSH2_k127_1506879_10	485913.Krac_9623	3.579e-128	415.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WLSH2_k127_1506879_28	1121936.AUHI01000006_gene1989	1.617e-55	204.0	28PN2@1|root,2ZCAV@2|Bacteria,1V2C1@1239|Firmicutes,4HGS6@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1506879_37	1120936.KB907225_gene2686	6.372e-10	69.0	COG0202@1|root,COG0202@2|Bacteria	2|Bacteria	K	RNA polymerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1506879_26	153721.MYP_430	1.398e-60	212.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,47PVI@768503|Cytophagia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
WLSH2_k127_1506879_32	1133849.O3I_010390	3.538e-35	138.0	COG5646@1|root,COG5646@2|Bacteria,2IT4Y@201174|Actinobacteria,4G31R@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WLSH2_k127_1506879_13	926569.ANT_03360	5.171e-102	338.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
WLSH2_k127_1506879_21	411490.ANACAC_02185	1.463e-76	272.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	aspC	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_1506879_20	1521187.JPIM01000016_gene3688	1.56e-82	280.0	COG2077@1|root,COG2077@2|Bacteria,2G8IQ@200795|Chloroflexi	200795|Chloroflexi	O	Redoxin	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	-
WLSH2_k127_1506879_3	1521187.JPIM01000016_gene3672	4.033e-195	616.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,3751U@32061|Chloroflexia	32061|Chloroflexia	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WLSH2_k127_1506879_25	86416.Clopa_3621	1.739e-63	226.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	-	-	2.7.11.1,3.5.1.124	ko:K03152,ko:K05520,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko01002	-	-	-	DJ-1_PfpI,ThiJ_like
WLSH2_k127_1506879_14	313606.M23134_06235	6.032e-101	343.0	COG3616@1|root,COG3616@2|Bacteria,4NJAX@976|Bacteroidetes,47TAU@768503|Cytophagia	976|Bacteroidetes	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
WLSH2_k127_1506879_2	324602.Caur_2083	3.839e-205	646.0	COG2211@1|root,COG2211@2|Bacteria,2G6RZ@200795|Chloroflexi,3764D@32061|Chloroflexia	32061|Chloroflexia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_1506879_7	383372.Rcas_2187	3.213e-147	481.0	COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi,3752N@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_1506879_4	357808.RoseRS_1072	4.277e-193	612.0	COG0076@1|root,COG0076@2|Bacteria,2GAD1@200795|Chloroflexi,376VF@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase class V	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
WLSH2_k127_1506879_36	1449044.JMLE01000012_gene3049	3.579e-14	85.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1506879_40	272562.CA_C0243	1.453e-05	57.0	COG0842@1|root,COG0842@2|Bacteria,1UZU6@1239|Firmicutes,24BPW@186801|Clostridia,36DU4@31979|Clostridiaceae	186801|Clostridia	V	ABC-2 type transporter	sagI	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH2_k127_1506879_35	509191.AEDB02000108_gene1630	6.378e-17	94.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
WLSH2_k127_1506879_29	448385.sce2707	8.898e-55	197.0	2E8ZQ@1|root,33397@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1506879_12	926569.ANT_08150	9.986e-103	342.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_1506879_23	1288963.ADIS_3103	4.381e-66	236.0	2ET8I@1|root,33KSM@2|Bacteria,4NZEX@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1506879_43	1410624.JNKK01000036_gene781	0.0001269	48.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,27PAH@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WLSH2_k127_1506879_38	1032480.MLP_51760	2.209e-09	62.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria,4DSW5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1506879_8	42256.RradSPS_0358	5.019e-142	485.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_1506879_27	251221.35212976	3.671e-58	208.0	COG1573@1|root,COG1573@2|Bacteria,1FZYH@1117|Cyanobacteria	1117|Cyanobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH2_k127_1506879_16	1189619.pgond44_14073	2.311e-90	329.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,TPR_12,TPR_7
WLSH2_k127_1506879_22	1121451.DESAM_22149	3.085e-70	244.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MA7Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
WLSH2_k127_1506879_34	1499685.CCFJ01000012_gene1766	4.982e-21	96.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HHIC@91061|Bacilli,1ZC3A@1386|Bacillus	91061|Bacilli	KT	LuxR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_15079_3	671143.DAMO_1706	5.499e-19	91.0	COG2250@1|root,COG2250@2|Bacteria,2NRCJ@2323|unclassified Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
WLSH2_k127_15079_1	383372.Rcas_1020	1.093e-32	129.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	HEPN,NTP_transf_2
WLSH2_k127_15079_4	926569.ANT_12240	1.611e-09	63.0	COG1468@1|root,COG1468@2|Bacteria,2G83H@200795|Chloroflexi	200795|Chloroflexi	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
WLSH2_k127_15079_0	28072.Nos7524_0144	9.965e-67	237.0	COG0582@1|root,COG0582@2|Bacteria,1GPZH@1117|Cyanobacteria,1HU9Q@1161|Nostocales	1117|Cyanobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
WLSH2_k127_15079_2	224325.AF_0099	9.4e-23	104.0	COG2405@1|root,arCOG00719@2157|Archaea,2XXKY@28890|Euryarchaeota	28890|Euryarchaeota	V	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	-
WLSH2_k127_1550041_2	1499967.BAYZ01000009_gene5337	0.0002709	52.0	2EKNX@1|root,33ECP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1550041_0	5180.EDO03054	2.237e-60	224.0	KOG0272@1|root,KOG0295@1|root,KOG0272@2759|Eukaryota,KOG0295@2759|Eukaryota,3AFR9@33154|Opisthokonta,3Q43U@4751|Fungi,3RM8R@4890|Ascomycota	4751|Fungi	A	NACHT domain	-	-	-	-	-	-	-	-	-	-	-	-	HET,NACHT,WD40
WLSH2_k127_1561261_9	595460.RRSWK_05050	4.629e-110	373.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
WLSH2_k127_1561261_13	595460.RRSWK_05050	1.495e-82	293.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
WLSH2_k127_1561261_10	593750.Metfor_1047	1.132e-105	361.0	arCOG09580@1|root,arCOG09580@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1561261_23	998674.ATTE01000001_gene970	1.77e-36	155.0	COG1881@1|root,COG1881@2|Bacteria,1NQK5@1224|Proteobacteria,1S0T6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP,YHYH
WLSH2_k127_1561261_15	313595.P700755_000276	7.677e-70	254.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,1HYD5@117743|Flavobacteriia,4C35P@83612|Psychroflexus	976|Bacteroidetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pectate_lyase_3,SGL
WLSH2_k127_1561261_25	313603.FB2170_17336	0.00055	46.0	COG0657@1|root,COG0657@2|Bacteria,4NH62@976|Bacteroidetes,1HYAU@117743|Flavobacteriia,2PG9S@252356|Maribacter	976|Bacteroidetes	G	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WLSH2_k127_1561261_11	867845.KI911784_gene1111	9.508e-101	345.0	COG2211@1|root,COG2211@2|Bacteria,2G6RZ@200795|Chloroflexi	200795|Chloroflexi	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_1561261_3	1265505.ATUG01000001_gene4484	1.612e-158	514.0	COG1053@1|root,COG1053@2|Bacteria,1QWW9@1224|Proteobacteria	1224|Proteobacteria	C	fad dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
WLSH2_k127_1561261_6	926550.CLDAP_19780	1.093e-126	413.0	COG0685@1|root,COG0685@2|Bacteria,2G7NU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
WLSH2_k127_1561261_22	926550.CLDAP_19770	5.861e-45	168.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
WLSH2_k127_1561261_14	234267.Acid_6580	6.033e-82	279.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria	234267.Acid_6580|-	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
WLSH2_k127_1561261_1	370438.PTH_1770	3.302e-215	677.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,26067@186807|Peptococcaceae	186801|Clostridia	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
WLSH2_k127_1561261_21	1122197.ATWI01000009_gene1614	3.129e-49	180.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,1S1Z5@1236|Gammaproteobacteria,466W9@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	4.2.1.149,4.2.1.17	ko:K01692,ko:K08299	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10675	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH2_k127_1561261_26	29908.U7PNR9	0.0006429	45.0	COG1028@1|root,KOG0725@2759|Eukaryota,39J7V@33154|Opisthokonta,3Q49F@4751|Fungi,3QVEC@4890|Ascomycota,21A3Z@147550|Sordariomycetes	4751|Fungi	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	TFIIA_gamma_C,TFIIA_gamma_N,adh_short,adh_short_C2
WLSH2_k127_1561261_5	1265505.ATUG01000001_gene4318	1.369e-131	434.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_1561261_2	1449126.JQKL01000003_gene1813	4.565e-205	656.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,26A1J@186813|unclassified Clostridiales	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_1561261_8	56780.SYN_01215	3.32e-111	375.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_1561261_16	926550.CLDAP_16300	1.286e-62	218.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
WLSH2_k127_1561261_7	867903.ThesuDRAFT_01275	7.137e-113	378.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,3WD6V@538999|Clostridiales incertae sedis	186801|Clostridia	C	acyl-CoA transferase carnitine dehydratase	-	-	2.8.3.19	ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
WLSH2_k127_1561261_17	1304874.JAFY01000002_gene577	4.204e-62	233.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
WLSH2_k127_1561261_18	1089553.Tph_c27670	2.199e-60	215.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548,ko:K14084	ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230	M00017,M00563	R00946,R09124,R09365	RC00035,RC00113,RC00732,RC01241,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
WLSH2_k127_1561261_24	399739.Pmen_4204	2.677e-17	92.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2,PAF-AH_p_II
WLSH2_k127_1561261_4	1123284.KB899048_gene1589	1.382e-134	446.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HB3V@91061|Bacilli,26NEF@186821|Sporolactobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_1561261_20	1265505.ATUG01000002_gene2759	9.652e-54	198.0	COG1600@1|root,COG1600@2|Bacteria,1NW4X@1224|Proteobacteria,4300M@68525|delta/epsilon subdivisions,2WVFS@28221|Deltaproteobacteria,2MNF3@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1561261_0	270374.MELB17_04792	6.268e-240	759.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,1RPXX@1236|Gammaproteobacteria,4657J@72275|Alteromonadaceae	1236|Gammaproteobacteria	CM	COG1042 Acyl-CoA synthetase (NDP forming)	pauA	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_1561261_19	211165.AJLN01000116_gene3204	1.098e-56	207.0	COG5486@1|root,COG5486@2|Bacteria,1GF5E@1117|Cyanobacteria	1117|Cyanobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
WLSH2_k127_1561261_12	1297569.MESS2_300088	6.548e-100	329.0	COG0604@1|root,COG0604@2|Bacteria,1MXIK@1224|Proteobacteria,2TQPR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	ccrA	-	1.1.1.1,1.3.1.85	ko:K00001,ko:K14446	ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220	M00373	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R09291	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_1607085_0	926550.CLDAP_27080	6.493e-135	436.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi	2|Bacteria	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	patA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K05830,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R01155,R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECIAI1_1343.ECIAI1_3220,iECSF_1327.ECSF_2916,iECs_1301.ECs3955,iZ_1308.Z4426	Aminotran_3
WLSH2_k127_1607085_3	926550.CLDAP_27070	7.735e-86	294.0	2BWNB@1|root,32WFI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1607085_1	926560.KE387023_gene3595	2.915e-115	409.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
WLSH2_k127_1607085_5	331678.Cphamn1_0275	2.634e-30	129.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
WLSH2_k127_1607085_6	1123371.ATXH01000033_gene423	1.942e-13	78.0	COG1309@1|root,COG1309@2|Bacteria,2GHH2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH2_k127_1607085_4	251221.35211874	7.628e-60	220.0	COG0596@1|root,COG0596@2|Bacteria,1G05K@1117|Cyanobacteria	1117|Cyanobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_1607085_7	1122609.AUGT01000013_gene4106	2.506e-10	64.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria,4DSW5@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1607085_2	42256.RradSPS_0358	1.859e-104	362.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_1654815_3	1232410.KI421421_gene3301	2.936e-33	134.0	COG0640@1|root,COG0640@2|Bacteria,1NCXP@1224|Proteobacteria,42TJG@68525|delta/epsilon subdivisions,2WSYR@28221|Deltaproteobacteria,43VCK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1654815_1	269799.Gmet_1792	4.4e-55	199.0	2B0BZ@1|root,31SP3@2|Bacteria,1RM1T@1224|Proteobacteria,42RVA@68525|delta/epsilon subdivisions,2WR20@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1654815_5	379066.GAU_3713	3.487e-08	59.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	Fer4,HTH_3,HTH_31
WLSH2_k127_1654815_6	102129.Lepto7375DRAFT_1049	6.66e-07	58.0	28KW4@1|root,2ZACH@2|Bacteria,1G2SE@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1654815_0	886293.Sinac_1249	0.0	2269.0	COG3459@1|root,COG3459@2|Bacteria,2IYJ0@203682|Planctomycetes	203682|Planctomycetes	G	Putative glucoamylase	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
WLSH2_k127_1654815_2	626887.J057_06391	1.979e-47	184.0	COG0589@1|root,COG0589@2|Bacteria,1NAHQ@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_1654815_4	316274.Haur_2048	1.374e-16	82.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi,376XZ@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
WLSH2_k127_1662606_1	266117.Rxyl_2810	2.665e-22	108.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WLSH2_k127_1662606_0	926569.ANT_18450	1.175e-77	267.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi	200795|Chloroflexi	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WLSH2_k127_1673698_1	880073.Calab_1809	5.07e-160	511.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_1673698_3	880073.Calab_0286	3.128e-130	424.0	COG1294@1|root,COG1294@2|Bacteria,2NS31@2323|unclassified Bacteria	2|Bacteria	C	PFAM Cytochrome bd ubiquinol oxidase, subunit II	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120	Cyt_bd_oxida_II
WLSH2_k127_1673698_2	469371.Tbis_2750	1.804e-150	490.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,4DZRD@85010|Pseudonocardiales	201174|Actinobacteria	C	Cytochrome bd-type quinol oxidase, subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
WLSH2_k127_1673698_11	279238.Saro_0194	8.19e-20	94.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2UAVK@28211|Alphaproteobacteria,2K421@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WLSH2_k127_1673698_8	317619.ANKN01000187_gene3820	1.293e-71	254.0	COG0682@1|root,COG0682@2|Bacteria,1G0H2@1117|Cyanobacteria,1MKRX@1212|Prochloraceae	1117|Cyanobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH2_k127_1673698_10	1307761.L21SP2_3047	2.458e-54	206.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
WLSH2_k127_1673698_4	926569.ANT_16830	4.775e-125	416.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi	200795|Chloroflexi	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WLSH2_k127_1673698_6	1211114.ALIP01000143_gene2266	7.775e-86	295.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,1T49M@1236|Gammaproteobacteria,1X4E9@135614|Xanthomonadales	135614|Xanthomonadales	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_1673698_9	504472.Slin_5207	4.444e-69	243.0	COG1216@1|root,COG1216@2|Bacteria,4NIW6@976|Bacteroidetes,47PUF@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_1673698_5	502025.Hoch_0348	7.76e-106	357.0	COG1621@1|root,COG1621@2|Bacteria,1RCMP@1224|Proteobacteria,432Y7@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1673698_0	1183438.GKIL_3722	3.844e-258	812.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WLSH2_k127_1673698_7	706587.Desti_5093	1.102e-80	302.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_16789_10	1210884.HG799474_gene15133	2.338e-07	61.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
WLSH2_k127_16789_9	326427.Cagg_3119	2.618e-10	64.0	2A426@1|root,30SKW@2|Bacteria,2GAFI@200795|Chloroflexi,375XZ@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_16789_2	1121346.KB899815_gene1901	3.741e-163	542.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26R22@186822|Paenibacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WLSH2_k127_16789_3	502025.Hoch_3258	2.052e-64	225.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,4385Z@68525|delta/epsilon subdivisions,2X3FT@28221|Deltaproteobacteria,2YVWY@29|Myxococcales	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WLSH2_k127_16789_7	502025.Hoch_3258	1.546e-18	85.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,4385Z@68525|delta/epsilon subdivisions,2X3FT@28221|Deltaproteobacteria,2YVWY@29|Myxococcales	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WLSH2_k127_16789_1	644282.Deba_0431	1.236e-167	546.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WLSH2_k127_16789_5	755178.Cyan10605_1187	1.16e-23	103.0	COG1708@1|root,COG1708@2|Bacteria,1G9J2@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH2_k127_16789_6	926550.CLDAP_07640	1.575e-19	89.0	COG2161@1|root,COG2161@2|Bacteria,2G9Q0@200795|Chloroflexi	200795|Chloroflexi	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WLSH2_k127_16789_4	383372.Rcas_1958	9.437e-31	125.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
WLSH2_k127_16789_8	1304880.JAGB01000001_gene901	1.437e-10	66.0	COG1708@1|root,COG1708@2|Bacteria,1VM1R@1239|Firmicutes,24UG9@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH2_k127_16789_0	926569.ANT_14870	2.035e-209	666.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WLSH2_k127_1699223_13	926560.KE387023_gene2131	1.826e-110	362.0	COG3694@1|root,COG3694@2|Bacteria,1WM9D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_6
WLSH2_k127_1699223_30	926560.KE387023_gene2132	6.664e-64	228.0	COG4587@1|root,COG4587@2|Bacteria,1WMG7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_6
WLSH2_k127_1699223_4	926560.KE387023_gene2133	8.079e-144	464.0	COG4586@1|root,COG4586@2|Bacteria,1WM9A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_1699223_56	926569.ANT_11780	1.926e-23	112.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WLSH2_k127_1699223_62	1268237.G114_01204	2.704e-15	90.0	COG0739@1|root,COG0739@2|Bacteria,1R6RZ@1224|Proteobacteria,1RP73@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	lasA	-	-	ko:K08642	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PPC,Peptidase_M23
WLSH2_k127_1699223_68	195103.CPF_0338	5.659e-06	58.0	COG1716@1|root,COG1716@2|Bacteria,1VF0E@1239|Firmicutes,24P12@186801|Clostridia,36KT8@31979|Clostridiaceae	186801|Clostridia	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
WLSH2_k127_1699223_67	1117318.PRUB_00625	8.774e-07	61.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S0G0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
WLSH2_k127_1699223_0	926569.ANT_10660	0.0	1222.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH2_k127_1699223_70	1278308.KB907079_gene2127	6.735e-05	46.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4FMW7@85023|Microbacteriaceae	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_1699223_57	926569.ANT_14010	5.643e-23	100.0	COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WLSH2_k127_1699223_63	1128421.JAGA01000002_gene1038	2.536e-14	76.0	COG1254@1|root,COG1254@2|Bacteria,2NQ0Z@2323|unclassified Bacteria	2|Bacteria	C	Acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WLSH2_k127_1699223_24	926569.ANT_19940	1.187e-71	258.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
WLSH2_k127_1699223_42	926550.CLDAP_05630	5.451e-49	186.0	COG0679@1|root,COG0679@2|Bacteria,2G90G@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
WLSH2_k127_1699223_28	926569.ANT_19930	4.495e-67	240.0	COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi	200795|Chloroflexi	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WLSH2_k127_1699223_19	926569.ANT_19920	1.318e-86	300.0	COG0750@1|root,COG0750@2|Bacteria,2G6GY@200795|Chloroflexi	200795|Chloroflexi	M	SMART PDZ DHR GLGF domain protein	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
WLSH2_k127_1699223_52	479434.Sthe_0786	5.16e-36	142.0	COG0537@1|root,COG0537@2|Bacteria,2G6VV@200795|Chloroflexi,27YE1@189775|Thermomicrobia	189775|Thermomicrobia	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WLSH2_k127_1699223_39	926569.ANT_28020	3.141e-50	189.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_4
WLSH2_k127_1699223_7	926550.CLDAP_24920	1.167e-122	402.0	COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi	200795|Chloroflexi	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WLSH2_k127_1699223_48	926569.ANT_28920	3.347e-40	160.0	28XMW@1|root,2ZJIW@2|Bacteria,2G9GS@200795|Chloroflexi	926569.ANT_28920|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1699223_29	304371.MCP_0966	6.823e-67	239.0	COG0863@1|root,arCOG00115@2157|Archaea,2Y8E2@28890|Euryarchaeota	28890|Euryarchaeota	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
WLSH2_k127_1699223_32	316274.Haur_3812	4.821e-60	225.0	COG0793@1|root,COG0793@2|Bacteria,2GAAX@200795|Chloroflexi,374TM@32061|Chloroflexia	32061|Chloroflexia	M	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41,Tricorn_C1
WLSH2_k127_1699223_65	926569.ANT_02430	4.115e-12	67.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1699223_36	926569.ANT_02430	2.085e-51	190.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1699223_55	1382306.JNIM01000001_gene144	1.75e-28	123.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi	200795|Chloroflexi	L	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
WLSH2_k127_1699223_8	926569.ANT_00500	1.323e-119	399.0	COG2211@1|root,COG2211@2|Bacteria,2G6B9@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
WLSH2_k127_1699223_66	1122939.ATUD01000003_gene3451	3.151e-09	59.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria,4CQ80@84995|Rubrobacteria	84995|Rubrobacteria	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WLSH2_k127_1699223_61	1121930.AQXG01000008_gene178	1.192e-15	80.0	COG1321@1|root,COG1321@2|Bacteria,4NGUP@976|Bacteroidetes,1IS2N@117747|Sphingobacteriia	976|Bacteroidetes	K	Iron dependent repressor, metal binding and dimerisation domain	sirR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WLSH2_k127_1699223_69	1246995.AFR_19695	5.068e-05	55.0	COG3170@1|root,COG3170@2|Bacteria,2I40K@201174|Actinobacteria,4D8QC@85008|Micromonosporales	201174|Actinobacteria	NU	Glycosyltransferase family 87	-	-	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
WLSH2_k127_1699223_1	926569.ANT_00530	3.29e-204	650.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
WLSH2_k127_1699223_53	926569.ANT_00520	1.271e-35	144.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi	200795|Chloroflexi	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
WLSH2_k127_1699223_15	926569.ANT_00510	2.2e-94	318.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WLSH2_k127_1699223_38	926569.ANT_06250	1.269e-50	188.0	COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi	200795|Chloroflexi	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
WLSH2_k127_1699223_18	316274.Haur_0048	5.234e-93	315.0	COG1235@1|root,COG1235@2|Bacteria,2G833@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WLSH2_k127_1699223_27	316274.Haur_0049	6.087e-68	242.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_1699223_46	1173028.ANKO01000193_gene5867	1.545e-41	168.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
WLSH2_k127_1699223_50	926569.ANT_07030	2.571e-37	147.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
WLSH2_k127_1699223_6	926569.ANT_07040	8.073e-133	432.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	yhfE	-	3.2.1.4	ko:K01179,ko:K01269	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
WLSH2_k127_1699223_34	926569.ANT_07040	1.964e-53	191.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	yhfE	-	3.2.1.4	ko:K01179,ko:K01269	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
WLSH2_k127_1699223_11	383372.Rcas_3959	1.435e-112	373.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
WLSH2_k127_1699223_49	313624.NSP_5230	1.32e-38	145.0	COG4680@1|root,COG4680@2|Bacteria,1G7BW@1117|Cyanobacteria,1HPS5@1161|Nostocales	1117|Cyanobacteria	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
WLSH2_k127_1699223_35	671143.DAMO_3092	5.016e-53	189.0	COG5499@1|root,COG5499@2|Bacteria,2NRMJ@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	-
WLSH2_k127_1699223_59	1430440.MGMSRv2_2383	1.912e-20	93.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,2JSDJ@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
WLSH2_k127_1699223_47	1469607.KK073769_gene6074	2.355e-40	153.0	COG3293@1|root,COG3293@2|Bacteria,1G0BW@1117|Cyanobacteria,1HNSC@1161|Nostocales	1117|Cyanobacteria	L	transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
WLSH2_k127_1699223_71	331869.BAL199_22882	0.0005997	43.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,2TURP@28211|Alphaproteobacteria,4BRIA@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
WLSH2_k127_1699223_43	485913.Krac_4709	1.209e-45	177.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
WLSH2_k127_1699223_45	926560.KE387023_gene3674	4.994e-43	159.0	COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
WLSH2_k127_1699223_23	485913.Krac_0962	4.436e-75	280.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
WLSH2_k127_1699223_21	926569.ANT_00170	1.76e-82	280.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WLSH2_k127_1699223_33	926560.KE387023_gene2631	1.378e-57	209.0	2EH2B@1|root,33AU9@2|Bacteria,1WMY7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH2_k127_1699223_3	926569.ANT_31560	1.516e-145	472.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WLSH2_k127_1699223_44	580327.Tthe_0526	2.505e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,42GT3@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_1699223_26	926569.ANT_31550	1.229e-69	239.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WLSH2_k127_1699223_22	926569.ANT_30100	4.828e-77	279.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
WLSH2_k127_1699223_41	926569.ANT_03600	2.911e-49	183.0	COG1225@1|root,COG1225@2|Bacteria,2G9KJ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_1699223_5	926569.ANT_19100	8.434e-134	436.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH2_k127_1699223_58	643648.Slip_1920	6.038e-23	109.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,42KK8@68298|Syntrophomonadaceae	186801|Clostridia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
WLSH2_k127_1699223_2	926569.ANT_19090	1.467e-178	569.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi	200795|Chloroflexi	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WLSH2_k127_1699223_9	526227.Mesil_1248	4.417e-119	400.0	COG3119@1|root,COG3119@2|Bacteria,1WM9P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
WLSH2_k127_1699223_12	1128421.JAGA01000001_gene2030	1.619e-111	372.0	COG1524@1|root,COG1524@2|Bacteria,2NQ0M@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WLSH2_k127_1699223_51	388401.RB2150_05393	3.933e-37	146.0	COG3038@1|root,COG3038@2|Bacteria,1PP9T@1224|Proteobacteria,2V9B2@28211|Alphaproteobacteria,3ZIMG@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WLSH2_k127_1699223_37	926569.ANT_06220	6.863e-51	184.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH2_k127_1699223_60	945713.IALB_0787	5.189e-18	87.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.11.1,4.6.1.1	ko:K01768,ko:K12132	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	DUF3467
WLSH2_k127_1699223_25	926569.ANT_06230	1.445e-71	248.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
WLSH2_k127_1699223_54	1121920.AUAU01000013_gene1720	8.112e-30	123.0	COG3613@1|root,COG3613@2|Bacteria	2|Bacteria	F	nucleoside 2-deoxyribosyltransferase	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
WLSH2_k127_1699223_17	926569.ANT_28000	2.238e-93	324.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
WLSH2_k127_1699223_14	926569.ANT_27990	2.901e-97	331.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926569.ANT_27990|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1699223_16	926569.ANT_03120	5.301e-94	319.0	COG4448@1|root,COG4448@2|Bacteria	2|Bacteria	E	L-asparaginase II	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_II
WLSH2_k127_1699223_20	926569.ANT_03110	4.872e-86	293.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH2_k127_1699223_10	926569.ANT_06880	3.124e-116	400.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
WLSH2_k127_1699223_31	926569.ANT_19610	1.047e-62	222.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WLSH2_k127_1699223_40	926569.ANT_25690	2.579e-49	182.0	COG3287@1|root,COG3287@2|Bacteria,2G7G0@200795|Chloroflexi	200795|Chloroflexi	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
WLSH2_k127_1704328_13	1265503.KB905161_gene3256	7.176e-07	53.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,1RX8V@1236|Gammaproteobacteria,2Q877@267889|Colwelliaceae	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WLSH2_k127_1704328_10	1392490.JHZX01000001_gene168	1.093e-20	103.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
WLSH2_k127_1704328_2	439235.Dalk_4420	1.584e-81	286.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,42USJ@68525|delta/epsilon subdivisions,2WQ3J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WLSH2_k127_1704328_7	1120972.AUMH01000008_gene2067	1.148e-45	174.0	COG1414@1|root,COG1414@2|Bacteria,1V6ZB@1239|Firmicutes,4HJH8@91061|Bacilli	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
WLSH2_k127_1704328_6	1167006.UWK_00398	3.017e-47	175.0	COG1247@1|root,COG1247@2|Bacteria,1REV2@1224|Proteobacteria,42UEY@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Acetyltransferase	ywnH	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_4
WLSH2_k127_1704328_9	926561.KB900622_gene618	1.618e-24	112.0	COG0778@1|root,COG0778@2|Bacteria,1UW3S@1239|Firmicutes,25M99@186801|Clostridia,3WC8N@53433|Halanaerobiales	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_1704328_5	1121085.AUCI01000045_gene70	8.605e-54	200.0	COG1788@1|root,COG1788@2|Bacteria,1UYH2@1239|Firmicutes,4HGBM@91061|Bacilli,1ZIHE@1386|Bacillus	91061|Bacilli	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WLSH2_k127_1704328_4	1121085.AUCI01000045_gene72	2.562e-61	220.0	COG2057@1|root,COG2057@2|Bacteria,1UDE4@1239|Firmicutes,4HDQF@91061|Bacilli,1ZHM8@1386|Bacillus	91061|Bacilli	I	Coenzyme A transferase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
WLSH2_k127_1704328_11	877414.ATWA01000006_gene136	8.768e-12	68.0	COG2768@1|root,COG2768@2|Bacteria,1VET2@1239|Firmicutes,24QUH@186801|Clostridia	186801|Clostridia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH2_k127_1704328_12	1283299.AUKG01000002_gene3731	2.23e-11	74.0	COG0454@1|root,COG0456@2|Bacteria,2HPI4@201174|Actinobacteria,4CQVU@84995|Rubrobacteria	84995|Rubrobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_1704328_0	504472.Slin_4020	9.936e-93	314.0	COG0657@1|root,COG0657@2|Bacteria,4NIQ0@976|Bacteroidetes,47JK6@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WLSH2_k127_1704328_1	1121346.KB899811_gene1710	9.047e-87	298.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,26R5U@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
WLSH2_k127_1704328_3	926550.CLDAP_06170	1.067e-63	228.0	COG1129@1|root,COG1129@2|Bacteria,2G8AK@200795|Chloroflexi	200795|Chloroflexi	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WLSH2_k127_1704328_8	1469948.JPNB01000001_gene875	3.637e-35	146.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
WLSH2_k127_1706937_8	926569.ANT_26250	9.454e-07	51.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
WLSH2_k127_1706937_9	326427.Cagg_2197	7.835e-06	51.0	2EPAC@1|root,33GX3@2|Bacteria,2GB3X@200795|Chloroflexi,377VD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1706937_3	926569.ANT_25910	1.391e-147	483.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	2|Bacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WLSH2_k127_1706937_6	926569.ANT_25330	1.453e-71	255.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
WLSH2_k127_1706937_5	926560.KE387027_gene263	1.151e-78	272.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
WLSH2_k127_1706937_2	1242864.D187_001830	3.992e-175	590.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2YWHV@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
WLSH2_k127_1706937_4	926569.ANT_13310	2.25e-102	349.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi	200795|Chloroflexi	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
WLSH2_k127_1706937_1	926550.CLDAP_40150	1.078e-190	612.0	COG1164@1|root,COG1164@2|Bacteria,2G5UV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH2_k127_1706937_0	926569.ANT_13300	7.691e-202	640.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
WLSH2_k127_1708010_1	1499967.BAYZ01000131_gene330	4.647e-32	128.0	2BY23@1|root,345FG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1708010_0	867845.KI911784_gene3669	8.633e-79	281.0	COG0443@1|root,COG0443@2|Bacteria,2GBRB@200795|Chloroflexi,3768Q@32061|Chloroflexia	32061|Chloroflexia	O	Hsp70 protein	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
WLSH2_k127_1708010_2	649638.Trad_1724	2.074e-05	47.0	COG4401@1|root,COG4401@2|Bacteria,1WJZD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
WLSH2_k127_1735649_2	604354.TSIB_1009	1.787e-160	527.0	COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota,242U3@183968|Thermococci	183968|Thermococci	C	aldehyde ferredoxin oxidoreductase	aor	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_1735649_27	1283299.AUKG01000003_gene649	1.124e-65	240.0	COG2355@1|root,COG2355@2|Bacteria,2HRND@201174|Actinobacteria,4CTQJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
WLSH2_k127_1735649_16	926550.CLDAP_13320	7.574e-102	342.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WLSH2_k127_1735649_0	926550.CLDAP_10200	3.958e-184	587.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_1735649_20	1235279.C772_01702	3.262e-92	314.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,4HCFJ@91061|Bacilli,26E46@186818|Planococcaceae	91061|Bacilli	G	COG1175 ABC-type sugar transport systems, permease components	-	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
WLSH2_k127_1735649_6	926550.CLDAP_10180	1.296e-135	439.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH2_k127_1735649_3	373903.Hore_15280	1.508e-155	502.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3WADV@53433|Halanaerobiales	186801|Clostridia	G	PFAM Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WLSH2_k127_1735649_13	485913.Krac_2351	2.246e-113	377.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WLSH2_k127_1735649_26	1227454.C446_01021	2.04e-67	241.0	COG1874@1|root,arCOG04085@2157|Archaea,2XSU6@28890|Euryarchaeota,23UX4@183963|Halobacteria	183963|Halobacteria	G	COG1874 Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1735649_22	1499967.BAYZ01000141_gene6143	2.142e-86	305.0	COG0001@1|root,COG0001@2|Bacteria,2NNV5@2323|unclassified Bacteria	2|Bacteria	H	PFAM aminotransferase class-III	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006553,GO:0006554,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016769,GO:0016999,GO:0017144,GO:0019475,GO:0019477,GO:0019665,GO:0019666,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046440,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.111,5.4.3.8	ko:K01845,ko:K21585	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272,R11607	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_1735649_1	1125973.JNLC01000010_gene1478	5.19e-174	555.0	COG1653@1|root,COG1653@2|Bacteria,1MX9J@1224|Proteobacteria,2U36T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_1735649_18	1125973.JNLC01000010_gene1477	4.617e-97	327.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TSH3@28211|Alphaproteobacteria,3K63G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
WLSH2_k127_1735649_9	1125973.JNLC01000010_gene1475	3.829e-122	403.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,3JT2D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter	MA20_13190	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
WLSH2_k127_1735649_25	357808.RoseRS_4112	2.001e-80	279.0	COG0371@1|root,COG0371@2|Bacteria,2G95F@200795|Chloroflexi	200795|Chloroflexi	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
WLSH2_k127_1735649_15	1173022.Cri9333_3939	4.455e-105	356.0	COG2211@1|root,COG2211@2|Bacteria,1GBZ6@1117|Cyanobacteria,1HF47@1150|Oscillatoriales	1117|Cyanobacteria	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_1735649_31	1499967.BAYZ01000041_gene2356	2.689e-30	136.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
WLSH2_k127_1735649_19	1444309.JAQG01000115_gene3194	6.161e-94	323.0	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,26UDI@186822|Paenibacillaceae	91061|Bacilli	E	Peptidase family M20/M25/M40	yodQ	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_1735649_4	118173.KB235914_gene3833	1.252e-153	491.0	COG0673@1|root,COG0673@2|Bacteria,1G18V@1117|Cyanobacteria,1HG44@1150|Oscillatoriales	1117|Cyanobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.335,1.1.99.28	ko:K00118,ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_1735649_28	1111479.AXAR01000009_gene2433	2.155e-42	165.0	COG2120@1|root,COG2120@2|Bacteria,1UYGC@1239|Firmicutes,4HJGK@91061|Bacilli	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WLSH2_k127_1735649_5	926569.ANT_08180	1.068e-140	453.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WLSH2_k127_1735649_21	926569.ANT_22350	5.447e-92	311.0	COG3394@1|root,COG3394@2|Bacteria,2G6X5@200795|Chloroflexi	200795|Chloroflexi	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
WLSH2_k127_1735649_7	1173022.Cri9333_3939	4.507e-130	428.0	COG2211@1|root,COG2211@2|Bacteria,1GBZ6@1117|Cyanobacteria,1HF47@1150|Oscillatoriales	1117|Cyanobacteria	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_1735649_29	1288963.ADIS_3302	3.939e-38	159.0	COG3356@1|root,COG3356@2|Bacteria,4NU9C@976|Bacteroidetes,47VT1@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
WLSH2_k127_1735649_30	278963.ATWD01000001_gene2540	3.137e-32	142.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WLSH2_k127_1735649_33	235909.GK3196	2.188e-07	63.0	COG3543@1|root,COG3543@2|Bacteria,1VFVM@1239|Firmicutes,4HIWH@91061|Bacilli,1WG5U@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
WLSH2_k127_1735649_17	926569.ANT_15020	2.839e-99	339.0	COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_1735649_11	1121381.JNIV01000214_gene3716	1.042e-117	396.0	COG2211@1|root,COG2211@2|Bacteria,1WIWY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_1735649_23	926569.ANT_11070	1.139e-85	293.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WLSH2_k127_1735649_14	926550.CLDAP_10170	2.599e-111	372.0	COG3356@1|root,COG3356@2|Bacteria,2G7ZP@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1735649_8	926550.CLDAP_16080	3.049e-129	425.0	COG1653@1|root,COG1653@2|Bacteria,2G958@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
WLSH2_k127_1735649_10	1499967.BAYZ01000095_gene4184	3.431e-120	393.0	COG1175@1|root,COG1175@2|Bacteria,2NQCB@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WLSH2_k127_1735649_12	926550.CLDAP_16100	3.546e-117	383.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	yesQ	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	iYO844.BSU06990	BPD_transp_1
WLSH2_k127_1735649_24	1499967.BAYZ01000095_gene4182	1.474e-81	293.0	COG1486@1|root,COG1486@2|Bacteria,2NQP2@2323|unclassified Bacteria	2|Bacteria	G	Family 4 glycosyl hydrolase	lplD	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WLSH2_k127_1735649_32	926550.CLDAP_10160	2.058e-28	132.0	COG0399@1|root,COG0399@2|Bacteria,2G7WW@200795|Chloroflexi	200795|Chloroflexi	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WLSH2_k127_1768053_2	671143.DAMO_0407	1.722e-232	733.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_1768053_1	926569.ANT_10850	1.003e-267	860.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636,ko:K07642	ko02020,map02020	M00434,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
WLSH2_k127_1768053_5	32057.KB217478_gene1220	9.225e-52	193.0	COG0300@1|root,COG0300@2|Bacteria,1GBUP@1117|Cyanobacteria,1HTYJ@1161|Nostocales	1117|Cyanobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_1768053_7	1128421.JAGA01000002_gene172	3.256e-29	126.0	COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria	2|Bacteria	I	Phosphate acyltransferases	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,Cytidylate_kin
WLSH2_k127_1768053_8	552811.Dehly_0238	1.138e-28	124.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH2_k127_1768053_4	926569.ANT_10810	1.019e-79	271.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WLSH2_k127_1768053_6	926569.ANT_15850	6.386e-40	168.0	COG4745@1|root,COG4745@2|Bacteria,2G9RB@200795|Chloroflexi	200795|Chloroflexi	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1768053_3	926569.ANT_27260	1.953e-126	434.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
WLSH2_k127_1768053_10	1122917.KB899664_gene2911	1.118e-15	85.0	COG0454@1|root,COG0456@2|Bacteria,1V7GR@1239|Firmicutes,4HM2Z@91061|Bacilli,26Y6V@186822|Paenibacillaceae	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_1768053_9	864702.OsccyDRAFT_1639	5.046e-26	113.0	COG3502@1|root,COG3502@2|Bacteria,1G99N@1117|Cyanobacteria,1HBZI@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF952)	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
WLSH2_k127_1768053_0	926569.ANT_15860	5.158e-320	1008.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
WLSH2_k127_1776445_5	536227.CcarbDRAFT_4777	1.571e-96	321.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
WLSH2_k127_1776445_4	926569.ANT_18650	2.989e-119	391.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH2_k127_1776445_8	926569.ANT_18660	1.5e-65	231.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
WLSH2_k127_1776445_0	926569.ANT_18670	2.689e-142	468.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
WLSH2_k127_1776445_2	926550.CLDAP_07480	2.002e-136	445.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH2_k127_1776445_6	926569.ANT_11510	1.428e-93	325.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1776445_15	1111479.AXAR01000032_gene3129	3.043e-05	56.0	COG5650@1|root,COG5650@2|Bacteria,1W08I@1239|Firmicutes,4HY85@91061|Bacilli	91061|Bacilli	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
WLSH2_k127_1776445_3	926569.ANT_11510	1.703e-119	400.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1776445_7	1382356.JQMP01000003_gene2108	3.846e-79	284.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
WLSH2_k127_1776445_1	926569.ANT_05240	3.312e-138	454.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
WLSH2_k127_1776445_13	1171373.PACID_22330	2.641e-18	94.0	COG3346@1|root,COG3346@2|Bacteria,2GR90@201174|Actinobacteria,4DR52@85009|Propionibacteriales	201174|Actinobacteria	S	SURF1 family	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	SURF1
WLSH2_k127_1776445_11	926569.ANT_05270	1.02e-53	196.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WLSH2_k127_1776445_9	926569.ANT_05280	3.51e-65	231.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
WLSH2_k127_1776445_10	926569.ANT_05300	1.219e-58	207.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WLSH2_k127_1813182_10	555500.I215_09521	1.354e-84	291.0	28J1N@1|root,2Z8YI@2|Bacteria,4NH1X@976|Bacteroidetes,1I0QB@117743|Flavobacteriia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WLSH2_k127_1813182_9	449447.MAE_54140	5.862e-87	301.0	28HTA@1|root,2Z806@2|Bacteria,1G35E@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1813182_0	335543.Sfum_3271	1.931e-318	995.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1Q4TM@1224|Proteobacteria,43A26@68525|delta/epsilon subdivisions,2X24Y@28221|Deltaproteobacteria,2MSDH@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1813182_14	797303.Natpe_4189	3.887e-72	266.0	COG4715@1|root,arCOG03429@2157|Archaea,2XUSY@28890|Euryarchaeota,23SPU@183963|Halobacteria	183963|Halobacteria	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
WLSH2_k127_1813182_18	391625.PPSIR1_07887	8.055e-55	206.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2YVU0@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
WLSH2_k127_1813182_28	272134.KB731324_gene2232	0.0001411	45.0	COG3293@1|root,2ZJP3@2|Bacteria,1GQG4@1117|Cyanobacteria,1HI2R@1150|Oscillatoriales	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
WLSH2_k127_1813182_12	926569.ANT_18520	2.483e-79	271.0	COG0170@1|root,COG0170@2|Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1813182_27	344747.PM8797T_16887	1.588e-07	65.0	COG1807@1|root,COG1807@2|Bacteria,2IZ75@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH2_k127_1813182_19	1408422.JHYF01000011_gene3398	4.516e-36	143.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,36KPD@31979|Clostridiaceae	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
WLSH2_k127_1813182_3	324602.Caur_3869	1.324e-308	959.0	COG1472@1|root,COG1472@2|Bacteria,2G84T@200795|Chloroflexi,3759W@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WLSH2_k127_1813182_4	926569.ANT_27030	1.811e-272	852.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WLSH2_k127_1813182_5	316274.Haur_0632	6.679e-146	471.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi,3752Z@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WLSH2_k127_1813182_23	561230.PC1_2136	4.871e-19	92.0	2E8SS@1|root,3333I@2|Bacteria,1NF8M@1224|Proteobacteria,1SJ9Y@1236|Gammaproteobacteria,1MSH9@122277|Pectobacterium	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1813182_13	926569.ANT_13070	4.294e-77	266.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi	200795|Chloroflexi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WLSH2_k127_1813182_26	643473.KB235930_gene4203	9.315e-11	66.0	COG3385@1|root,COG3385@2|Bacteria,1G27F@1117|Cyanobacteria,1HMUZ@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_1813182_21	32057.KB217483_gene10078	3.298e-33	141.0	COG3385@1|root,2ZA2Q@2|Bacteria,1G4UP@1117|Cyanobacteria,1HTE9@1161|Nostocales	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_1813182_15	1121121.KB894296_gene681	3.833e-66	247.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,26TP2@186822|Paenibacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_1813182_24	251229.Chro_4009	2.13e-15	90.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,3VI20@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
WLSH2_k127_1813182_22	1242864.D187_003686	3.05e-22	112.0	COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria,1MUIQ@1224|Proteobacteria,42XEE@68525|delta/epsilon subdivisions,2WT63@28221|Deltaproteobacteria,2Z2GG@29|Myxococcales	28221|Deltaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT
WLSH2_k127_1813182_11	1385935.N836_34245	1.346e-80	278.0	2DBFF@1|root,2Z8YA@2|Bacteria,1G2KB@1117|Cyanobacteria,1HFHB@1150|Oscillatoriales	1117|Cyanobacteria	L	Helix-turn-helix of DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
WLSH2_k127_1813182_8	479434.Sthe_1638	1.304e-89	307.0	COG0624@1|root,COG0624@2|Bacteria,2G60R@200795|Chloroflexi,27Y02@189775|Thermomicrobia	189775|Thermomicrobia	E	peptidase dimerisation domain protein	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WLSH2_k127_1813182_20	326427.Cagg_1682	7.285e-34	133.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_23570	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_34
WLSH2_k127_1813182_7	927677.ALVU02000001_gene4704	7.742e-104	346.0	COG1131@1|root,COG1131@2|Bacteria,1G3BQ@1117|Cyanobacteria,1H4K5@1142|Synechocystis	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH2_k127_1813182_17	326427.Cagg_1684	3.372e-57	207.0	COG1668@1|root,COG1668@2|Bacteria,2G9RA@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WLSH2_k127_1813182_1	1121430.JMLG01000004_gene880	3.357e-318	984.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24DPN@186801|Clostridia	186801|Clostridia	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WLSH2_k127_1813182_6	357808.RoseRS_3083	2.918e-143	468.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH2_k127_1813182_2	926569.ANT_16290	5.202e-313	969.0	COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS
WLSH2_k127_1813182_16	926569.ANT_15950	7.226e-59	214.0	COG1608@1|root,COG1608@2|Bacteria,2G6TH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aspartate glutamate uridylate kinase	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH2_k127_1828596_4	926569.ANT_02540	6.704e-73	254.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WLSH2_k127_1828596_5	595537.Varpa_1467	1.546e-17	84.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2VVJM@28216|Betaproteobacteria,4AEUN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
WLSH2_k127_1828596_0	635013.TherJR_2465	9.582e-170	553.0	COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,249N1@186801|Clostridia,260S4@186807|Peptococcaceae	186801|Clostridia	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_1828596_2	926569.ANT_07470	7.269e-88	297.0	COG1116@1|root,COG1116@2|Bacteria,2G8C7@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
WLSH2_k127_1828596_1	926569.ANT_07480	2.7e-118	389.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
WLSH2_k127_1828596_3	926569.ANT_07490	3.308e-80	274.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
WLSH2_k127_1828596_6	309801.trd_0544	7.675e-05	52.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WLSH2_k127_1879783_4	1121423.JONT01000015_gene1322	3.468e-07	55.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,261DM@186807|Peptococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_1879783_2	477974.Daud_0819	2.172e-08	59.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia	186801|Clostridia	L	resolvase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_1879783_3	314230.DSM3645_28217	1.525e-07	54.0	COG1961@1|root,COG1961@2|Bacteria,2IXU9@203682|Planctomycetes	203682|Planctomycetes	L	DNA invertase Pin	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_1879783_1	314278.NB231_09273	2.405e-22	100.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria	1224|Proteobacteria	L	Resolvase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_1879783_0	383372.Rcas_1516	1.253e-40	154.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
WLSH2_k127_1962481_2	926550.CLDAP_06250	6.5e-86	299.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MFS_1
WLSH2_k127_1962481_1	1382359.JIAL01000001_gene647	3.092e-99	336.0	COG0153@1|root,COG0153@2|Bacteria,3Y300@57723|Acidobacteria,2JI7E@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WLSH2_k127_1962481_0	1408473.JHXO01000011_gene3193	1.43e-146	477.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,2FWDF@200643|Bacteroidia	976|Bacteroidetes	C	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
WLSH2_k127_1962481_11	1232410.KI421421_gene3301	3.975e-07	53.0	COG0640@1|root,COG0640@2|Bacteria,1NCXP@1224|Proteobacteria,42TJG@68525|delta/epsilon subdivisions,2WSYR@28221|Deltaproteobacteria,43VCK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1962481_9	1232410.KI421421_gene3301	1.414e-13	73.0	COG0640@1|root,COG0640@2|Bacteria,1NCXP@1224|Proteobacteria,42TJG@68525|delta/epsilon subdivisions,2WSYR@28221|Deltaproteobacteria,43VCK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1962481_10	661478.OP10G_2458	1.749e-07	55.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
WLSH2_k127_1962481_4	926569.ANT_24350	1.226e-69	244.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WLSH2_k127_1962481_7	243164.DET0295	4.457e-38	154.0	COG4974@1|root,COG4974@2|Bacteria,2G8U5@200795|Chloroflexi,34DNB@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
WLSH2_k127_1962481_5	391625.PPSIR1_07887	5.242e-60	220.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,42RQP@68525|delta/epsilon subdivisions,2WNQ7@28221|Deltaproteobacteria,2YVU0@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos,Metallophos_2
WLSH2_k127_1962481_3	1514668.JOOA01000002_gene2712	1.801e-76	265.0	COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,24C3A@186801|Clostridia,3WJ2E@541000|Ruminococcaceae	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WLSH2_k127_1962481_6	1121422.AUMW01000017_gene1926	1.954e-50	187.0	COG5340@1|root,COG5340@2|Bacteria,1TQSK@1239|Firmicutes,247JC@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
WLSH2_k127_2030856_1	526225.Gobs_0746	2.053e-14	74.0	COG1262@1|root,COG3170@1|root,COG1262@2|Bacteria,COG3170@2|Bacteria,2IBYZ@201174|Actinobacteria	201174|Actinobacteria	NU	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	PknH_C,TIR_2
WLSH2_k127_2030856_3	1123487.KB892849_gene262	1.338e-13	74.0	COG0775@1|root,COG0775@2|Bacteria,1R441@1224|Proteobacteria,2W87D@28216|Betaproteobacteria,2KZJZ@206389|Rhodocyclales	206389|Rhodocyclales	F	SEFIR domain	-	-	-	-	-	-	-	-	-	-	-	-	SEFIR
WLSH2_k127_2030856_0	1173024.KI912152_gene425	6.488e-111	377.0	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_2030856_2	926569.ANT_14030	2.369e-14	74.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH2_k127_2064455_8	926569.ANT_07080	1.209e-85	293.0	COG0583@1|root,COG0583@2|Bacteria,2G77H@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WLSH2_k127_2064455_11	665571.STHERM_c19020	7.03e-33	136.0	COG0517@1|root,COG0517@2|Bacteria,2J6JU@203691|Spirochaetes	203691|Spirochaetes	S	CBS domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
WLSH2_k127_2064455_10	868131.MSWAN_0796	1.041e-36	144.0	COG0500@1|root,arCOG01631@2157|Archaea	2157|Archaea	Q	RNA methylase	-	GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	CMAS,DOT1,Methyltransf_25,Methyltransf_31,PrmA
WLSH2_k127_2064455_0	696747.NIES39_M01500	0.0	1193.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1H81U@1150|Oscillatoriales	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_2064455_6	1122611.KB903940_gene1706	2.788e-94	312.0	28N0F@1|root,2ZB6V@2|Bacteria,2I31F@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
WLSH2_k127_2064455_12	1443665.JACA01000045_gene4749	3.024e-19	93.0	COG3232@1|root,COG3232@2|Bacteria,4PH3M@976|Bacteroidetes,1IHU1@117743|Flavobacteriia,2YJKV@290174|Aquimarina	976|Bacteroidetes	E	5-carboxymethyl-2-hydroxymuconate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	CHMI
WLSH2_k127_2064455_2	1122223.KB890696_gene142	2.392e-155	495.0	COG0346@1|root,COG0346@2|Bacteria,1WICV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
WLSH2_k127_2064455_9	266117.Rxyl_0200	2.132e-81	276.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4CSRQ@84995|Rubrobacteria	84995|Rubrobacteria	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
WLSH2_k127_2064455_5	309801.trd_0904	1.158e-97	324.0	COG2120@1|root,COG2120@2|Bacteria,2G8FR@200795|Chloroflexi,27Y9R@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	4.2.1.83	ko:K16515	ko00362,map00362	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	PIG-L
WLSH2_k127_2064455_4	926569.ANT_07120	2.187e-110	364.0	COG0657@1|root,COG0657@2|Bacteria,2G747@200795|Chloroflexi	200795|Chloroflexi	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WLSH2_k127_2064455_7	926569.ANT_07120	6.799e-86	294.0	COG0657@1|root,COG0657@2|Bacteria,2G747@200795|Chloroflexi	200795|Chloroflexi	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WLSH2_k127_2064455_3	926569.ANT_07110	1.474e-151	484.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
WLSH2_k127_2064455_1	926569.ANT_07100	3.546e-226	709.0	COG1129@1|root,COG1129@2|Bacteria,2G7YP@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
WLSH2_k127_2070903_6	572477.Alvin_0642	9.764e-05	46.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_2070903_5	1209072.ALBT01000076_gene72	3.448e-05	53.0	2ENTF@1|root,33GEM@2|Bacteria,1NZ01@1224|Proteobacteria,1SPT8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2070903_1	765420.OSCT_2995	5.436e-52	191.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
WLSH2_k127_2070903_3	744872.Spica_2810	1.148e-40	154.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WLSH2_k127_2070903_4	765420.OSCT_2995	7.632e-40	156.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
WLSH2_k127_2070903_0	765420.OSCT_2991	2.654e-78	280.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K00406,ko:K03889,ko:K17222,ko:K19713	ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020	M00151,M00156,M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3
WLSH2_k127_2070903_2	765420.OSCT_2992	2.658e-43	163.0	COG0723@1|root,COG0723@2|Bacteria,2GB28@200795|Chloroflexi,377SJ@32061|Chloroflexia	32061|Chloroflexia	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
WLSH2_k127_2092970_1	498761.HM1_3055	3.233e-94	319.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
WLSH2_k127_2092970_4	498761.HM1_3055	1.435e-06	54.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
WLSH2_k127_2092970_3	656519.Halsa_1049	2.939e-36	147.0	2D0M5@1|root,32T8U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2092970_6	765420.OSCT_1735	0.0001758	50.0	COG3103@1|root,COG4991@2|Bacteria,2GBHW@200795|Chloroflexi,3761I@32061|Chloroflexia	32061|Chloroflexia	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
WLSH2_k127_2092970_5	1524467.IV04_04135	1.608e-05	50.0	COG0732@1|root,COG0732@2|Bacteria,1R5R8@1224|Proteobacteria	1224|Proteobacteria	L	restriction -modification system	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
WLSH2_k127_2092970_2	1230342.CTM_26780	2.778e-50	190.0	COG0732@1|root,COG0732@2|Bacteria,1VC5J@1239|Firmicutes,24MS4@186801|Clostridia,36VV7@31979|Clostridiaceae	186801|Clostridia	V	COG0732 Restriction endonuclease S subunits	-	-	-	-	-	-	-	-	-	-	-	-	Methylase_S
WLSH2_k127_2092970_0	46234.ANA_C10110	3.18e-139	451.0	COG0286@1|root,COG0286@2|Bacteria,1G132@1117|Cyanobacteria,1HQG8@1161|Nostocales	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
WLSH2_k127_2137664_1	1236514.BAKL01000004_gene494	2.349e-36	140.0	COG0507@1|root,COG0507@2|Bacteria,4NJCM@976|Bacteroidetes,2FQUV@200643|Bacteroidia,4AKVJ@815|Bacteroidaceae	976|Bacteroidetes	L	Helix-hairpin-helix containing domain	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
WLSH2_k127_2137664_0	926550.CLDAP_38260	8.178e-185	597.0	COG0507@1|root,COG0632@1|root,COG0507@2|Bacteria,COG0632@2|Bacteria,2G626@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
WLSH2_k127_2137664_2	1116472.MGMO_57c00220	5.49e-10	60.0	COG3385@1|root,COG3385@2|Bacteria,1NIWM@1224|Proteobacteria,1S5FT@1236|Gammaproteobacteria,1XFX0@135618|Methylococcales	135618|Methylococcales	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_2159355_0	1133849.O3I_027875	2.663e-146	485.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4FX0N@85025|Nocardiaceae	201174|Actinobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_2159355_6	304371.MCP_2203	3.43e-31	134.0	COG1266@1|root,arCOG02766@2157|Archaea	2157|Archaea	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_2159355_1	485913.Krac_0164	2.349e-55	208.0	COG0454@1|root,COG0456@2|Bacteria,2G8DV@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_2159355_4	1114856.C496_09266	5.923e-40	158.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,23WZT@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_2159355_7	91464.S7335_589	3.597e-31	133.0	COG0596@1|root,COG0596@2|Bacteria,1GFX0@1117|Cyanobacteria	1117|Cyanobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_2159355_8	485913.Krac_5383	1.158e-26	116.0	COG0346@1|root,COG0622@1|root,COG0346@2|Bacteria,COG0622@2|Bacteria,2G8MU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_2159355_2	317025.Tcr_1073	7.058e-46	176.0	COG1266@1|root,COG1266@2|Bacteria,1MWXT@1224|Proteobacteria,1S05B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_2159355_5	1047013.AQSP01000068_gene2283	1.807e-33	134.0	2FIP3@1|root,34AEW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2159355_11	1191523.MROS_1929	2.079e-07	59.0	2FIP3@1|root,34AEW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2159355_10	316274.Haur_0706	2.272e-15	89.0	COG3042@1|root,COG5513@1|root,COG3042@2|Bacteria,COG5513@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
WLSH2_k127_2159355_9	1521187.JPIM01000149_gene405	2.439e-16	92.0	COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
WLSH2_k127_2159355_3	1235798.C817_03844	8.557e-41	157.0	COG1309@1|root,COG1309@2|Bacteria,1UY1A@1239|Firmicutes,24CX4@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WLSH2_k127_2159355_12	216432.CA2559_12543	3.284e-05	48.0	COG2197@1|root,COG2197@2|Bacteria,4NMTW@976|Bacteroidetes,1I1JF@117743|Flavobacteriia	976|Bacteroidetes	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_2184346_4	378806.STAUR_5097	8.284e-20	102.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07499	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_29,HTH_32,HTH_33
WLSH2_k127_2184346_0	378806.STAUR_5098	1.205e-93	320.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,42Q11@68525|delta/epsilon subdivisions,2WKFK@28221|Deltaproteobacteria,2Z242@29|Myxococcales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
WLSH2_k127_2184346_2	391612.CY0110_26712	6.956e-28	118.0	COG1598@1|root,COG1598@2|Bacteria,1G9MA@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
WLSH2_k127_2184346_1	933262.AXAM01000063_gene611	1.987e-28	115.0	COG1724@1|root,COG1724@2|Bacteria,1NP3B@1224|Proteobacteria	1224|Proteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
WLSH2_k127_2184346_3	927677.ALVU02000001_gene2433	4.951e-20	91.0	COG2929@1|root,COG2929@2|Bacteria,1G805@1117|Cyanobacteria	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
WLSH2_k127_2196657_1	1441629.PCH70_47870	0.0002844	47.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RX8I@1236|Gammaproteobacteria,1Z9PF@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	QU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
WLSH2_k127_2196657_0	981384.AEYW01000006_gene2983	6.073e-58	218.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
WLSH2_k127_2219980_6	1356852.N008_00900	1.193e-133	438.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WLSH2_k127_2219980_17	316278.SynRCC307_0256	2.416e-08	63.0	COG0745@1|root,COG0745@2|Bacteria,1G1EZ@1117|Cyanobacteria,1GZ8T@1129|Synechococcus	1117|Cyanobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	rpaA	-	-	ko:K10697	ko02020,map02020	M00467	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_2219980_7	926550.CLDAP_05410	1.31e-123	409.0	COG1167@1|root,COG1167@2|Bacteria,2G81Z@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WLSH2_k127_2219980_11	118173.KB235912_gene38	8.095e-44	163.0	COG5611@1|root,COG5611@2|Bacteria	2|Bacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_2219980_2	383372.Rcas_1569	2.279e-165	548.0	COG1404@1|root,COG1404@2|Bacteria,2G80X@200795|Chloroflexi,375FY@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH2_k127_2219980_12	1267535.KB906767_gene735	2.892e-41	164.0	COG1073@1|root,COG1073@2|Bacteria,3Y5TG@57723|Acidobacteria,2JNP5@204432|Acidobacteriia	204432|Acidobacteriia	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2219980_13	1312959.KI914656_gene787	4.053e-41	159.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
WLSH2_k127_2219980_10	545243.BAEV01000109_gene2788	4.935e-45	167.0	COG0454@1|root,COG0456@2|Bacteria,1VC1N@1239|Firmicutes,24MWN@186801|Clostridia,36V25@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
WLSH2_k127_2219980_5	926569.ANT_15460	3.965e-141	460.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WLSH2_k127_2219980_19	660470.Theba_1130	5.384e-05	48.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
WLSH2_k127_2219980_1	926569.ANT_23460	1.009e-167	535.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WLSH2_k127_2219980_0	926569.ANT_23450	2.731e-178	566.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WLSH2_k127_2219980_14	926569.ANT_23440	4.336e-39	158.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	6.3.2.4	ko:K01921,ko:K03589	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
WLSH2_k127_2219980_3	926569.ANT_23430	1.688e-146	472.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WLSH2_k127_2219980_8	926569.ANT_23420	6.531e-105	349.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WLSH2_k127_2219980_4	926569.ANT_23400	6.153e-146	476.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH2_k127_2219980_9	926569.ANT_23380	8.158e-92	308.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WLSH2_k127_2243714_30	1123368.AUIS01000006_gene577	9.217e-21	99.0	COG3437@1|root,COG3437@2|Bacteria,1QWW7@1224|Proteobacteria,1T5NB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH2_k127_2243714_25	118166.JH976537_gene1045	3.163e-33	142.0	COG1511@1|root,COG2319@1|root,COG1511@2|Bacteria,COG2319@2|Bacteria,1GHUJ@1117|Cyanobacteria,1HHZK@1150|Oscillatoriales	1117|Cyanobacteria	S	GUN4-like	-	-	-	-	-	-	-	-	-	-	-	-	GUN4
WLSH2_k127_2243714_18	357808.RoseRS_2229	1.353e-66	251.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WLSH2_k127_2243714_20	330214.NIDE4035	2.485e-46	189.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
WLSH2_k127_2243714_34	570952.ATVH01000011_gene58	7.82e-13	74.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,2JQV9@204441|Rhodospirillales	204441|Rhodospirillales	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WLSH2_k127_2243714_26	2074.JNYD01000008_gene1228	9.266e-33	145.0	COG0443@1|root,COG3391@1|root,COG4995@1|root,COG0443@2|Bacteria,COG3391@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,HSP70
WLSH2_k127_2243714_17	351160.RCIX1913	1.566e-69	250.0	COG1852@1|root,arCOG02078@2157|Archaea,2XXPW@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
WLSH2_k127_2243714_14	1321778.HMPREF1982_02491	1.431e-74	256.0	COG4845@1|root,COG4845@2|Bacteria,1UPU1@1239|Firmicutes,25CW3@186801|Clostridia	186801|Clostridia	V	PFAM Chloramphenicol acetyltransferase	-	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
WLSH2_k127_2243714_31	316067.Geob_1157	1.934e-20	95.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
WLSH2_k127_2243714_4	926569.ANT_07740	7.123e-137	449.0	COG0577@1|root,COG0577@2|Bacteria,2G6MK@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_2243714_10	926569.ANT_07730	3.138e-91	321.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
WLSH2_k127_2243714_12	926569.ANT_07720	3.483e-86	293.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_2243714_29	497964.CfE428DRAFT_0631	7.858e-25	108.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
WLSH2_k127_2243714_35	1121019.AUMN01000038_gene23	4.355e-12	72.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WLSH2_k127_2243714_39	105559.Nwat_3042	4.844e-08	62.0	COG3832@1|root,COG3832@2|Bacteria,1N34T@1224|Proteobacteria,1S642@1236|Gammaproteobacteria,1WYKR@135613|Chromatiales	135613|Chromatiales	S	PFAM Polyketide cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WLSH2_k127_2243714_38	1214101.BN159_0442	8.568e-09	62.0	COG1359@1|root,COG1359@2|Bacteria,2GT9F@201174|Actinobacteria	201174|Actinobacteria	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2243714_24	1174528.JH992898_gene3078	1.203e-40	155.0	COG1670@1|root,COG1670@2|Bacteria,1G63R@1117|Cyanobacteria,1JJYB@1189|Stigonemataceae	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH2_k127_2243714_33	378806.STAUR_4577	2.749e-14	79.0	COG0727@1|root,COG0727@2|Bacteria,1NJH8@1224|Proteobacteria,432FF@68525|delta/epsilon subdivisions,2XA02@28221|Deltaproteobacteria,2YW1E@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
WLSH2_k127_2243714_11	867845.KI911784_gene835	2.377e-88	300.0	COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi,375I3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
WLSH2_k127_2243714_41	1122613.ATUP01000001_gene723	0.0005702	51.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2TR7U@28211|Alphaproteobacteria,43WW4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	COG0668 Small-conductance mechanosensitive channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
WLSH2_k127_2243714_3	1169154.KB897780_gene2126	1.293e-139	452.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
WLSH2_k127_2243714_8	335543.Sfum_4027	2.722e-98	335.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2MQDN@213462|Syntrophobacterales	1224|Proteobacteria	KT	Stage II sporulation	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2,sCache_2
WLSH2_k127_2243714_7	1487953.JMKF01000043_gene2591	3.749e-100	341.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
WLSH2_k127_2243714_13	926550.CLDAP_24490	1.65e-78	275.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH2_k127_2243714_22	469616.FMAG_01339	3.285e-41	164.0	COG1175@1|root,COG1175@2|Bacteria,379SM@32066|Fusobacteria	32066|Fusobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10193	ko02010,map02010	M00202	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.11	-	-	BPD_transp_1
WLSH2_k127_2243714_9	926569.ANT_13390	3.091e-95	316.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
WLSH2_k127_2243714_40	377629.TERTU_0521	0.000224	53.0	COG1555@1|root,COG1555@2|Bacteria,1N2AZ@1224|Proteobacteria,1SG4T@1236|Gammaproteobacteria,2PQ0F@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
WLSH2_k127_2243714_2	926569.ANT_14720	5.585e-230	719.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH2_k127_2243714_16	926569.ANT_14710	1.943e-70	248.0	COG0084@1|root,COG0084@2|Bacteria,2G6F2@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WLSH2_k127_2243714_6	926569.ANT_14700	4.298e-107	356.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
WLSH2_k127_2243714_15	1144275.COCOR_04923	8.573e-73	257.0	COG3613@1|root,COG3613@2|Bacteria,1NBEC@1224|Proteobacteria	1224|Proteobacteria	F	nucleoside 2-deoxyribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2243714_21	926569.ANT_04110	1.57e-41	158.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
WLSH2_k127_2243714_0	926569.ANT_04080	5.043e-274	855.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi	200795|Chloroflexi	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
WLSH2_k127_2243714_27	449447.MAE_37310	3.422e-32	139.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Peptidase_C14,Pkinase,TIR_2
WLSH2_k127_2243714_28	526225.Gobs_0746	4.555e-31	135.0	COG1262@1|root,COG3170@1|root,COG1262@2|Bacteria,COG3170@2|Bacteria,2IBYZ@201174|Actinobacteria	201174|Actinobacteria	NU	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	PknH_C,TIR_2
WLSH2_k127_2243714_37	1089547.KB913013_gene3162	5.093e-09	68.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,47KF5@768503|Cytophagia	976|Bacteroidetes	O	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
WLSH2_k127_2243714_19	765420.OSCT_3196	1.842e-58	228.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WLSH2_k127_2243714_5	926550.CLDAP_00050	2.087e-110	362.0	COG0588@1|root,COG0588@2|Bacteria,2G822@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WLSH2_k127_2243714_1	926569.ANT_20730	1.931e-242	769.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WLSH2_k127_2258468_16	572477.Alvin_0642	7.855e-07	53.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_2258468_18	7897.ENSLACP00000000230	0.0006163	49.0	COG0500@1|root,KOG1269@2759|Eukaryota,38CU5@33154|Opisthokonta,3BHPW@33208|Metazoa,3CZZR@33213|Bilateria,48D3D@7711|Chordata,499VX@7742|Vertebrata	33208|Metazoa	I	Tellurite resistance protein TehB	-	-	2.1.1.103	ko:K05929	ko00564,map00564	-	R02037,R06868,R06869	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_2258468_0	765420.OSCT_1688	2.512e-116	385.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WLSH2_k127_2258468_4	765420.OSCT_1686	1.829e-94	323.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH2_k127_2258468_6	357808.RoseRS_2229	6.133e-69	256.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WLSH2_k127_2258468_5	926569.ANT_12150	5.827e-76	277.0	COG0834@1|root,COG0834@2|Bacteria,2G6HE@200795|Chloroflexi	200795|Chloroflexi	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WLSH2_k127_2258468_8	272134.KB731324_gene1880	9.092e-52	188.0	COG3153@1|root,COG3153@2|Bacteria,1G6H9@1117|Cyanobacteria,1HBUU@1150|Oscillatoriales	1117|Cyanobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
WLSH2_k127_2258468_14	1242864.D187_001257	7.847e-21	97.0	COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,42WIT@68525|delta/epsilon subdivisions,2X0TU@28221|Deltaproteobacteria,2Z2N8@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH2_k127_2258468_15	1242864.D187_001257	1.181e-07	54.0	COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,42WIT@68525|delta/epsilon subdivisions,2X0TU@28221|Deltaproteobacteria,2Z2N8@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH2_k127_2258468_12	485916.Dtox_1955	1.276e-24	107.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_2258468_2	439235.Dalk_0771	2.854e-99	330.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,42Q5R@68525|delta/epsilon subdivisions,2WM6U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
WLSH2_k127_2258468_13	1121324.CLIT_11c00570	4.051e-24	106.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,25QP7@186804|Peptostreptococcaceae	186801|Clostridia	K	response regulator	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_2258468_10	370438.PTH_1831	4.427e-25	108.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_2258468_11	1173027.Mic7113_5472	5.315e-25	109.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1G1FK@1117|Cyanobacteria,1H8GM@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
WLSH2_k127_2258468_3	68170.KL590486_gene9692	2.433e-96	324.0	COG1131@1|root,COG1131@2|Bacteria,2IBP5@201174|Actinobacteria,4E9YU@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_2258468_7	1385514.N782_09870	4.239e-66	235.0	COG1277@1|root,COG1277@2|Bacteria,1V787@1239|Firmicutes,4IRME@91061|Bacilli,2YBAS@289201|Pontibacillus	91061|Bacilli	S	Bacitracin ABC transporter permease	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
WLSH2_k127_2258468_9	1541065.JRFE01000026_gene2122	2.568e-37	144.0	COG0824@1|root,COG0824@2|Bacteria,1G6JT@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
WLSH2_k127_2258468_1	765420.OSCT_1468	3.761e-104	351.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH2_k127_2258468_17	1123508.JH636453_gene5800	3.558e-05	56.0	COG3391@1|root,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WLSH2_k127_2389605_8	113355.CM001775_gene1440	5.119e-44	168.0	28NKA@1|root,2ZBM5@2|Bacteria,1G5FU@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2389605_1	926569.ANT_05390	2.279e-121	397.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
WLSH2_k127_2389605_0	926569.ANT_05380	8.754e-170	539.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi	200795|Chloroflexi	H	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
WLSH2_k127_2389605_3	1128421.JAGA01000002_gene455	1.868e-99	340.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WLSH2_k127_2389605_4	926569.ANT_30400	1.886e-92	315.0	COG2355@1|root,COG2355@2|Bacteria,2G6FQ@200795|Chloroflexi	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WLSH2_k127_2389605_2	324602.Caur_1560	3.804e-113	378.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi,375H2@32061|Chloroflexia	32061|Chloroflexia	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_2389605_6	768710.DesyoDRAFT_4220	7.996e-67	245.0	COG5598@1|root,COG5598@2|Bacteria,1V335@1239|Firmicutes,24GX0@186801|Clostridia,26435@186807|Peptococcaceae	186801|Clostridia	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_2389605_5	266117.Rxyl_0312	2.114e-68	256.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2GJW4@201174|Actinobacteria,4CQV5@84995|Rubrobacteria	84995|Rubrobacteria	EU	Peptidase S9, prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WLSH2_k127_2389605_9	1047013.AQSP01000134_gene1338	8.987e-36	143.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_2393530_2	357808.RoseRS_3898	8.236e-57	205.0	COG0673@1|root,COG0673@2|Bacteria,2G7R0@200795|Chloroflexi,377Y3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WLSH2_k127_2393530_1	926569.ANT_30490	1.62e-64	231.0	COG0496@1|root,COG0496@2|Bacteria	2|Bacteria	P	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WLSH2_k127_2393530_3	1144343.PMI41_04610	3.666e-37	145.0	COG1762@1|root,COG1762@2|Bacteria,1N6D6@1224|Proteobacteria,2UEPG@28211|Alphaproteobacteria,43KHK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	GT	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.200	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_EIIA_2
WLSH2_k127_2393530_4	1040982.AXAL01000040_gene56	7.023e-19	90.0	COG3414@1|root,COG3414@2|Bacteria,1N5JB@1224|Proteobacteria,2UDYS@28211|Alphaproteobacteria,43KMU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Phosphotransferase system, galactitol-specific IIB component	-	-	2.7.1.200	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_IIB
WLSH2_k127_2393530_0	1231190.NA8A_22913	2.066e-113	373.0	COG3775@1|root,COG3775@2|Bacteria,1MVRC@1224|Proteobacteria,2TXEI@28211|Alphaproteobacteria,43I4M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	system Galactitol-specific IIC component	-	-	-	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5.1	-	-	EIIC-GAT
WLSH2_k127_2416979_2	926569.ANT_02640	2.536e-86	290.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_2416979_0	926569.ANT_02630	1.427e-120	393.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WLSH2_k127_2416979_1	1128421.JAGA01000002_gene1719	1.859e-106	350.0	COG1117@1|root,COG1117@2|Bacteria,2NP2B@2323|unclassified Bacteria	2|Bacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WLSH2_k127_2446300_2	926569.ANT_01110	1.005e-35	145.0	COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
WLSH2_k127_2446300_0	926569.ANT_19870	6.478e-161	512.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WLSH2_k127_2446300_3	240015.ACP_1735	4.391e-13	72.0	29WS1@1|root,30ID4@2|Bacteria,3Y5IE@57723|Acidobacteria,2JK0W@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
WLSH2_k127_2446300_1	572544.Ilyop_1609	2.869e-58	211.0	2EYYJ@1|root,33S5A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2499753_14	177437.HRM2_44710	3.701e-54	194.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2499753_19	177437.HRM2_44710	4.305e-23	101.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2499753_9	926550.CLDAP_07690	3.22e-110	364.0	COG1131@1|root,COG1131@2|Bacteria,2G7U7@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_2499753_20	1429046.RR21198_0371	6.076e-17	86.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WLSH2_k127_2499753_8	926550.CLDAP_07700	5.036e-114	375.0	COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_2499753_17	765420.OSCT_0043	3.709e-39	163.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
WLSH2_k127_2499753_7	926550.CLDAP_07720	5.824e-119	394.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
WLSH2_k127_2499753_15	926550.CLDAP_07730	2.035e-46	174.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_10010	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH2_k127_2499753_6	316274.Haur_3936	2.167e-120	400.0	COG0477@1|root,COG2223@1|root,COG2223@2|Bacteria,COG2814@2|Bacteria,2GA7I@200795|Chloroflexi,3780K@32061|Chloroflexia	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_2499753_5	926550.CLDAP_06530	7.767e-137	445.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
WLSH2_k127_2499753_12	1189619.pgond44_14073	1.926e-77	294.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes,1I0JH@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,TPR_12,TPR_7
WLSH2_k127_2499753_18	420324.KI911972_gene3032	9.502e-28	116.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,1JYYS@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
WLSH2_k127_2499753_10	880072.Desac_0095	1.653e-98	333.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
WLSH2_k127_2499753_1	383372.Rcas_0950	1.463e-233	732.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,376MS@32061|Chloroflexia	32061|Chloroflexia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
WLSH2_k127_2499753_22	273068.TTE1222	4.233e-14	79.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,42GW2@68295|Thermoanaerobacterales	186801|Clostridia	I	PFAM Biotin lipoyl attachment	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
WLSH2_k127_2499753_2	357808.RoseRS_3692	3.638e-172	549.0	COG1883@1|root,COG1883@2|Bacteria,2G7ZJ@200795|Chloroflexi,3768I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
WLSH2_k127_2499753_23	648996.Theam_0536	1.048e-07	63.0	COG0454@1|root,COG0456@2|Bacteria,2G48Y@200783|Aquificae	200783|Aquificae	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WLSH2_k127_2499753_3	926569.ANT_02910	1.412e-165	534.0	COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
WLSH2_k127_2499753_13	926569.ANT_02900	1.02e-72	255.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WLSH2_k127_2499753_4	926569.ANT_02220	1.085e-141	455.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
WLSH2_k127_2499753_11	926569.ANT_02230	2.223e-90	308.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH2_k127_2499753_16	926569.ANT_02240	6.98e-41	153.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi	200795|Chloroflexi	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WLSH2_k127_2499753_0	926569.ANT_02250	8.518e-257	803.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WLSH2_k127_2499753_21	926569.ANT_02260	1.457e-14	74.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi	200795|Chloroflexi	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
WLSH2_k127_2551000_0	485913.Krac_2962	7.754e-101	342.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
WLSH2_k127_2551000_1	102129.Lepto7375DRAFT_4471	7.214e-26	113.0	COG2405@1|root,COG2405@2|Bacteria,1G5DX@1117|Cyanobacteria,1HBC1@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
WLSH2_k127_2551000_2	313624.NSP_40740	1.988e-24	106.0	COG2886@1|root,COG2886@2|Bacteria,1G8EZ@1117|Cyanobacteria,1HQ18@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
WLSH2_k127_257703_17	56780.SYN_02800	1.669e-13	80.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,42M1M@68525|delta/epsilon subdivisions,2X5M1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WLSH2_k127_257703_5	926569.ANT_28730	1.092e-118	396.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_257703_6	926569.ANT_28720	1.708e-114	372.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_257703_0	926569.ANT_23610	9.318e-196	619.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WLSH2_k127_257703_18	443218.AS9A_0525	1.011e-07	60.0	COG2839@1|root,COG2839@2|Bacteria,2IQDE@201174|Actinobacteria,2397M@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
WLSH2_k127_257703_20	1160718.SU9_11513	3.108e-07	63.0	COG1653@1|root,COG1653@2|Bacteria,2GN9T@201174|Actinobacteria	201174|Actinobacteria	G	solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_257703_3	926569.ANT_05540	1.947e-130	424.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WLSH2_k127_257703_12	926569.ANT_25530	2.739e-35	144.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WLSH2_k127_257703_4	926569.ANT_05530	1.41e-128	421.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WLSH2_k127_257703_7	926569.ANT_05520	6.283e-109	363.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WLSH2_k127_257703_1	926569.ANT_23160	1.07e-185	610.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi	200795|Chloroflexi	L	PFAM SMC domain protein	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
WLSH2_k127_257703_8	485913.Krac_2500	1.563e-76	271.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
WLSH2_k127_257703_11	926569.ANT_29050	3.476e-44	166.0	COG3005@1|root,COG3005@2|Bacteria,2G748@200795|Chloroflexi	200795|Chloroflexi	C	NapC/NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
WLSH2_k127_257703_2	926569.ANT_29060	2.316e-176	563.0	COG3303@1|root,COG3303@2|Bacteria,2G5UX@200795|Chloroflexi	200795|Chloroflexi	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
WLSH2_k127_257703_14	867903.ThesuDRAFT_01409	3.145e-26	115.0	COG2847@1|root,COG2847@2|Bacteria	2|Bacteria	P	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
WLSH2_k127_257703_19	1537994.JQFW01000056_gene637	1.779e-07	59.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria,46BZW@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_257703_13	234267.Acid_2932	1.24e-32	138.0	COG0664@1|root,COG0664@2|Bacteria,3Y4WU@57723|Acidobacteria	57723|Acidobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_257703_9	926569.ANT_01450	5.705e-70	240.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
WLSH2_k127_257703_15	304371.MCP_2443	6.03e-19	98.0	arCOG08211@1|root,arCOG08211@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_257703_16	309798.COPRO5265_1458	5.314e-16	91.0	2DTCK@1|root,33JQD@2|Bacteria,1VNW3@1239|Firmicutes,24X19@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2612423_13	1122176.KB903531_gene2970	1.459e-55	202.0	COG2267@1|root,COG2267@2|Bacteria,4NIU9@976|Bacteroidetes	976|Bacteroidetes	I	Alpha beta hydrolase	ytpA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
WLSH2_k127_2612423_25	765420.OSCT_2813	2.257e-12	75.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	ko:K07013,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	V4R
WLSH2_k127_2612423_18	926569.ANT_03770	1.71e-34	139.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
WLSH2_k127_2612423_16	926569.ANT_13840	1.016e-42	168.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_2612423_17	926569.ANT_13860	8.075e-42	162.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
WLSH2_k127_2612423_1	926569.ANT_13870	1.263e-192	609.0	COG4962@1|root,COG4962@2|Bacteria,2G7K7@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WLSH2_k127_2612423_23	1232437.KL662077_gene1836	1.013e-16	83.0	2EU69@1|root,33MNV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2612423_24	29581.BW37_05050	7.196e-16	90.0	COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2VNYQ@28216|Betaproteobacteria,475KV@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,Response_reg
WLSH2_k127_2612423_6	926569.ANT_13890	6.279e-100	331.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_2612423_5	926569.ANT_13900	1.135e-101	345.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_13900|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2612423_14	1254432.SCE1572_02910	1.227e-46	181.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MZW@68525|delta/epsilon subdivisions,2WIV1@28221|Deltaproteobacteria,2YUVS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PocR
WLSH2_k127_2612423_2	926569.ANT_13960	2.81e-177	571.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WLSH2_k127_2612423_8	926569.ANT_13970	3.967e-81	280.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WLSH2_k127_2612423_4	926569.ANT_13980	3.177e-108	357.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WLSH2_k127_2612423_7	926569.ANT_13990	1.996e-91	308.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WLSH2_k127_2612423_12	926569.ANT_22890	1.425e-65	233.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
WLSH2_k127_2612423_9	926569.ANT_22900	1.01e-77	268.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi	200795|Chloroflexi	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
WLSH2_k127_2612423_20	771875.Ferpe_0714	3.745e-21	106.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
WLSH2_k127_2612423_15	926569.ANT_22920	5.326e-45	164.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi	200795|Chloroflexi	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WLSH2_k127_2612423_22	926569.ANT_22930	8.43e-19	90.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi	200795|Chloroflexi	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WLSH2_k127_2612423_21	926569.ANT_22940	9.651e-20	89.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
WLSH2_k127_2612423_10	926569.ANT_22950	1.98e-76	263.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WLSH2_k127_2612423_11	671143.DAMO_1520	1.842e-67	237.0	COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WLSH2_k127_2612423_0	671143.DAMO_0407	3.091e-270	845.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_2612423_19	671143.DAMO_1519	3.721e-25	106.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_2641064_2	1121946.AUAX01000003_gene1573	5.392e-55	198.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4DA4P@85008|Micromonosporales	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	regX3	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_2641064_1	316274.Haur_4664	7.829e-82	289.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_2641064_6	1123242.JH636434_gene5180	7.615e-07	54.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
WLSH2_k127_2641064_4	640511.BC1002_4772	1.777e-36	140.0	COG0526@1|root,COG0526@2|Bacteria,1RA5V@1224|Proteobacteria,2VQX7@28216|Betaproteobacteria,1KFIZ@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
WLSH2_k127_2641064_0	316274.Haur_2134	3.252e-128	418.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
WLSH2_k127_2641064_3	926569.ANT_11150	5.663e-52	193.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi	200795|Chloroflexi	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
WLSH2_k127_2641064_5	1321778.HMPREF1982_02132	4.695e-12	67.0	2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2657085_0	1321778.HMPREF1982_02247	1.983e-149	487.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,267T0@186813|unclassified Clostridiales	186801|Clostridia	KL	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
WLSH2_k127_2657085_3	926569.ANT_22190	6.786e-20	95.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_2657085_4	864069.MicloDRAFT_00004300	2.295e-06	54.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,DUF3105,HTH_23,HTH_Tnp_4,rve
WLSH2_k127_2657085_1	1306990.BARG01000018_gene1846	1.293e-80	278.0	COG1609@1|root,COG1609@2|Bacteria,2GK7G@201174|Actinobacteria	201174|Actinobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,HTH_Tnp_4
WLSH2_k127_2657085_2	1713.JOFV01000018_gene213	4.613e-41	156.0	2EJRI@1|root,32U8K@2|Bacteria,2IT18@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WLSH2_k127_2657085_5	756499.Desde_0552	1.698e-05	53.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,24QD8@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM
WLSH2_k127_2698909_2	42256.RradSPS_0358	2.197e-40	158.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_2698909_4	485913.Krac_1095	9.902e-12	69.0	2DRAK@1|root,33AYS@2|Bacteria	485913.Krac_1095|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2698909_0	1345697.M493_09900	1.776e-48	179.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1WE27@129337|Geobacillus	91061|Bacilli	EGP	LacY proton/sugar symporter	tetA_3	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
WLSH2_k127_2698909_1	406124.ACPC01000043_gene1820	3.475e-44	168.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,Sugar_tr
WLSH2_k127_2698909_3	1101188.KI912155_gene1889	1.124e-24	107.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,1W9JV@1268|Micrococcaceae	201174|Actinobacteria	G	pyruvate phosphate dikinase, PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_2741808_23	926569.ANT_19170	9.542e-08	65.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	ko:K04066,ko:K07037,ko:K17266	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400,ko04147	-	-	-	Band_7
WLSH2_k127_2741808_5	1009370.ALO_05268	4.379e-51	188.0	COG0613@1|root,COG0613@2|Bacteria,1VCKE@1239|Firmicutes,4H57V@909932|Negativicutes	909932|Negativicutes	S	PHP-associated	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
WLSH2_k127_2741808_16	926569.ANT_08190	1.857e-24	103.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WLSH2_k127_2741808_13	926569.ANT_30350	5.533e-32	132.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2741808_6	861299.J421_2299	1.985e-47	182.0	COG4127@1|root,COG4127@2|Bacteria,1ZV3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
WLSH2_k127_2741808_27	1279017.AQYJ01000022_gene2719	0.0003699	53.0	COG3063@1|root,COG3063@2|Bacteria,1R0M2@1224|Proteobacteria,1T4K4@1236|Gammaproteobacteria,46DCA@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8,Transglut_core
WLSH2_k127_2741808_20	765420.OSCT_2071	2.116e-09	71.0	COG2114@1|root,COG2202@1|root,COG2114@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564	-	ko:K03320,ko:K11525	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.11	-	-	Guanylate_cyc,PAS_9
WLSH2_k127_2741808_11	765420.OSCT_1712	2.357e-34	152.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WLSH2_k127_2741808_3	926550.CLDAP_08440	7.745e-65	228.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_2741808_15	926569.ANT_23300	2.959e-25	110.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WLSH2_k127_2741808_4	926550.CLDAP_08440	2.918e-57	206.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_2741808_9	317936.Nos7107_4563	4.028e-37	155.0	COG4928@1|root,COG4928@2|Bacteria,1G0KU@1117|Cyanobacteria,1HM31@1161|Nostocales	1117|Cyanobacteria	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
WLSH2_k127_2741808_14	402777.KB235898_gene5099	8.772e-31	141.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,TPR_1,TPR_8
WLSH2_k127_2741808_19	1191523.MROS_1992	1.649e-09	72.0	COG4783@1|root,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
WLSH2_k127_2741808_21	179408.Osc7112_0028	6.947e-09	69.0	COG0457@1|root,COG0457@2|Bacteria,1G3MN@1117|Cyanobacteria,1H8AK@1150|Oscillatoriales	1117|Cyanobacteria	K	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
WLSH2_k127_2741808_24	313612.L8106_15774	2.529e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1H9PH@1150|Oscillatoriales	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
WLSH2_k127_2741808_26	6334.EFV60666	6.34e-05	55.0	COG0428@1|root,KOG4642@1|root,KOG2693@2759|Eukaryota,KOG4642@2759|Eukaryota,38FZT@33154|Opisthokonta,3BEK2@33208|Metazoa,3CS6P@33213|Bilateria,40ATZ@6231|Nematoda	33208|Metazoa	P	Histidine-rich membrane protein KE4 homolog	SLC39A7	GO:0000003,GO:0000041,GO:0001667,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005801,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0006873,GO:0006875,GO:0006882,GO:0006928,GO:0006950,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0008021,GO:0008150,GO:0008324,GO:0009636,GO:0009888,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010312,GO:0010631,GO:0010632,GO:0012505,GO:0015075,GO:0015318,GO:0016020,GO:0016477,GO:0019222,GO:0019725,GO:0019953,GO:0022412,GO:0022414,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030133,GO:0030154,GO:0030234,GO:0030334,GO:0030424,GO:0030707,GO:0030855,GO:0031090,GO:0031323,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032879,GO:0033106,GO:0033238,GO:0034220,GO:0036477,GO:0040011,GO:0040012,GO:0042069,GO:0042175,GO:0042221,GO:0042592,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044456,GO:0044464,GO:0044703,GO:0045202,GO:0046873,GO:0046915,GO:0046916,GO:0048468,GO:0048471,GO:0048477,GO:0048609,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051179,GO:0051234,GO:0051239,GO:0051270,GO:0051674,GO:0051704,GO:0055065,GO:0055069,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060429,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070382,GO:0070838,GO:0071577,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0080090,GO:0090130,GO:0090132,GO:0097038,GO:0097458,GO:0097501,GO:0097708,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:0098772,GO:0098793,GO:0098827,GO:0099503,GO:0120025,GO:1990359,GO:2000026,GO:2000145,GO:2000274	-	ko:K14713	-	-	-	-	ko00000,ko02000	2.A.5.4.3,2.A.5.4.4,2.A.5.4.7	-	-	Zip
WLSH2_k127_2741808_12	867845.KI911784_gene1274	7.744e-34	148.0	COG0457@1|root,COG0457@2|Bacteria	867845.KI911784_gene1274|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2741808_22	394503.Ccel_0631	3.057e-08	58.0	COG0348@1|root,COG0348@2|Bacteria,1V143@1239|Firmicutes,25BBT@186801|Clostridia,36FQI@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_5,Fer4_9
WLSH2_k127_2741808_0	765420.OSCT_2998	1.26e-120	401.0	COG1251@1|root,COG1251@2|Bacteria,2G6YZ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pyr_redox_2
WLSH2_k127_2741808_8	765420.OSCT_2999	3.873e-45	171.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
WLSH2_k127_2741808_1	765420.OSCT_3000	2.212e-102	349.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
WLSH2_k127_2741808_7	926569.ANT_00760	1.914e-46	173.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WLSH2_k127_2741808_10	41431.PCC8801_3792	3.907e-35	145.0	2B8KV@1|root,321W5@2|Bacteria,1GMTM@1117|Cyanobacteria,3KKAC@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2741808_25	1121930.AQXG01000021_gene1675	9.398e-07	60.0	2DQS1@1|root,338C0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2741808_2	479434.Sthe_0243	5.99e-66	232.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_2741808_17	301.JNHE01000002_gene2354	3.006e-18	91.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,1RNPP@1236|Gammaproteobacteria,1YEYN@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
WLSH2_k127_2812948_1	926550.CLDAP_18930	9.293e-156	500.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WLSH2_k127_2812948_0	118163.Ple7327_2930	3.873e-157	508.0	COG4992@1|root,COG4992@2|Bacteria,1G4MC@1117|Cyanobacteria,3VMJX@52604|Pleurocapsales	1117|Cyanobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_2812948_4	1122603.ATVI01000011_gene2119	4.646e-110	364.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X790@135614|Xanthomonadales	135614|Xanthomonadales	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WLSH2_k127_2812948_3	926550.CLDAP_33840	1.675e-127	415.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WLSH2_k127_2812948_7	1216932.CM240_3316	1.279e-52	199.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,36FZK@31979|Clostridiaceae	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
WLSH2_k127_2812948_5	329726.AM1_4991	1.327e-94	317.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1G3BJ@1117|Cyanobacteria	1117|Cyanobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
WLSH2_k127_2812948_6	1565314.OA34_01920	1.878e-78	272.0	COG0697@1|root,COG0697@2|Bacteria,1MXX1@1224|Proteobacteria,42UPB@68525|delta/epsilon subdivisions	1224|Proteobacteria	EG	EamA-like transporter family	yedA	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_2812948_2	247490.KSU1_C0108	1.067e-132	430.0	COG0174@1|root,COG0174@2|Bacteria,2IXHM@203682|Planctomycetes	203682|Planctomycetes	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WLSH2_k127_2818019_2	63737.Npun_F1222	4.359e-208	707.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HINJ@1161|Nostocales	1117|Cyanobacteria	L	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
WLSH2_k127_2818019_13	867845.KI911784_gene2472	3.711e-55	224.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
WLSH2_k127_2818019_12	479434.Sthe_1268	4.455e-62	225.0	COG4454@1|root,COG4454@2|Bacteria,2GBEQ@200795|Chloroflexi,27Z6N@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2818019_0	926569.ANT_22450	0.0	1065.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
WLSH2_k127_2818019_10	926569.ANT_22460	2.983e-74	257.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WLSH2_k127_2818019_8	926569.ANT_15400	3.982e-103	346.0	COG0667@1|root,COG0667@2|Bacteria,2G6QZ@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_2818019_5	926569.ANT_13870	4.239e-131	432.0	COG4962@1|root,COG4962@2|Bacteria,2G7K7@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WLSH2_k127_2818019_19	225849.swp_0420	1.815e-10	73.0	COG4961@1|root,COG4961@2|Bacteria,1QV5Z@1224|Proteobacteria	1224|Proteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
WLSH2_k127_2818019_21	1267535.KB906767_gene1382	5.024e-07	59.0	COG4961@1|root,COG4961@2|Bacteria,3Y95G@57723|Acidobacteria	57723|Acidobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
WLSH2_k127_2818019_11	765420.OSCT_1933	1.248e-70	254.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G89B@200795|Chloroflexi,377XT@32061|Chloroflexia	200795|Chloroflexi	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBP_BcsQ,Response_reg
WLSH2_k127_2818019_17	1306174.JODP01000013_gene7620	1.666e-33	140.0	COG5002@1|root,COG5002@2|Bacteria,2I2TP@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,dCache_1
WLSH2_k127_2818019_1	926569.ANT_12650	1.972e-283	881.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WLSH2_k127_2818019_20	1541960.KQ78_02245	1.528e-07	55.0	2961X@1|root,2ZTCF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2818019_6	1121920.AUAU01000017_gene1235	9.534e-126	406.0	COG0289@1|root,COG0289@2|Bacteria	2|Bacteria	E	4-hydroxy-tetrahydrodipicolinate reductase	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
WLSH2_k127_2818019_18	1382315.JPOI01000001_gene598	1.529e-22	102.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,1WGPA@129337|Geobacillus	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WLSH2_k127_2818019_3	635013.TherJR_0871	3.408e-186	595.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2613E@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH2_k127_2818019_9	485915.Dret_0923	5.163e-96	322.0	COG0697@1|root,COG0697@2|Bacteria,1Q9QV@1224|Proteobacteria,43293@68525|delta/epsilon subdivisions,2WXT3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2818019_15	1906.SFRA_17115	6.672e-45	174.0	COG2365@1|root,COG2365@2|Bacteria,2IR8R@201174|Actinobacteria	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
WLSH2_k127_2818019_4	289376.THEYE_A1151	3.351e-158	514.0	COG0064@1|root,COG0064@2|Bacteria,3J0FK@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WLSH2_k127_2818019_22	1123075.AUDP01000012_gene3499	9.344e-07	54.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia,3WKBH@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_2818019_16	871968.DESME_07925	7.211e-35	143.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_2818019_7	926550.CLDAP_18930	1.127e-119	393.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WLSH2_k127_2900827_3	1307759.JOMJ01000003_gene1698	9.301e-13	78.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2M8V2@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
WLSH2_k127_2900827_1	634956.Geoth_0283	2.756e-132	437.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,1WE58@129337|Geobacillus	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WLSH2_k127_2900827_0	926569.ANT_02400	1.035e-163	522.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
WLSH2_k127_2900827_2	926569.ANT_12820	8.017e-26	115.0	COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi	200795|Chloroflexi	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_290300_4	1131269.AQVV01000005_gene375	2.884e-20	92.0	COG0224@1|root,COG0224@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
WLSH2_k127_290300_3	926569.ANT_20140	7.101e-92	311.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	2|Bacteria	M	PFAM Glycosyl transferase family 2	wcqE	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
WLSH2_k127_290300_2	1312959.KI914645_gene983	5.238e-161	525.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,1W8QW@1268|Micrococcaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
WLSH2_k127_290300_0	926569.ANT_27610	4.093e-259	807.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	200795|Chloroflexi	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WLSH2_k127_290300_5	867845.KI911784_gene13	9.291e-16	84.0	COG0640@1|root,COG0640@2|Bacteria,2GB64@200795|Chloroflexi,377ES@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WLSH2_k127_290300_1	595494.Tola_1002	4.563e-237	740.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1S0YQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WLSH2_k127_2996890_15	335541.Swol_0731	1.022e-53	203.0	COG0472@1|root,COG0472@2|Bacteria	2|Bacteria	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	wbpL	-	2.7.8.33,2.7.8.35	ko:K02851,ko:K13007	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
WLSH2_k127_2996890_4	56780.SYN_02684	7.436e-155	516.0	COG5360@1|root,COG5360@2|Bacteria,1MZ5X@1224|Proteobacteria,42PG1@68525|delta/epsilon subdivisions,2WP6V@28221|Deltaproteobacteria,2MRGQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
WLSH2_k127_2996890_22	401053.AciPR4_1803	1.173e-10	74.0	COG3595@1|root,COG3595@2|Bacteria,3Y4HG@57723|Acidobacteria,2JJ7G@204432|Acidobacteriia	204432|Acidobacteriia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WLSH2_k127_2996890_16	324602.Caur_0399	4.955e-35	140.0	COG1595@1|root,COG1595@2|Bacteria,2GBQ7@200795|Chloroflexi,376YC@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_2996890_8	926569.ANT_28800	2.222e-135	441.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_2996890_17	1144319.PMI16_02691	3.435e-24	109.0	COG0454@1|root,COG0456@2|Bacteria,1N8A4@1224|Proteobacteria,2VWFS@28216|Betaproteobacteria,478WZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_2996890_6	1128421.JAGA01000002_gene1976	8.625e-153	489.0	COG3458@1|root,COG3458@2|Bacteria,2NQIP@2323|unclassified Bacteria	2|Bacteria	Q	Acetyl xylan esterase (AXE1)	cah3	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005975,GO:0005976,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009308,GO:0009987,GO:0010383,GO:0010410,GO:0016787,GO:0016788,GO:0016999,GO:0017144,GO:0019213,GO:0019752,GO:0030653,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043645,GO:0044036,GO:0044106,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0045491,GO:0046483,GO:0046555,GO:0046872,GO:0047739,GO:0052689,GO:0071554,GO:0071704,GO:0072338,GO:1901266,GO:1901360,GO:1901564	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
WLSH2_k127_2996890_2	926569.ANT_28810	1.489e-173	550.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
WLSH2_k127_2996890_20	1121373.KB903629_gene382	4.279e-11	77.0	COG3405@1|root,COG3794@1|root,COG3866@1|root,COG4886@1|root,COG3405@2|Bacteria,COG3794@2|Bacteria,COG3866@2|Bacteria,COG4886@2|Bacteria,4PMDJ@976|Bacteroidetes,47TS5@768503|Cytophagia	976|Bacteroidetes	CG	G8	-	-	-	-	-	-	-	-	-	-	-	-	G8
WLSH2_k127_2996890_21	1268239.PALB_24680	5.12e-11	65.0	2AAWD@1|root,3109H@2|Bacteria,1N31N@1224|Proteobacteria	1224|Proteobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
WLSH2_k127_2996890_18	390989.JOEG01000005_gene1900	5.78e-18	90.0	COG1249@1|root,COG1249@2|Bacteria,2I5DW@201174|Actinobacteria	201174|Actinobacteria	C	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
WLSH2_k127_2996890_0	926569.ANT_28820	5.335e-192	607.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
WLSH2_k127_2996890_3	926569.ANT_24720	1.828e-173	560.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
WLSH2_k127_2996890_1	926569.ANT_19080	4.086e-180	574.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WLSH2_k127_2996890_5	760568.Desku_1807	2.806e-154	500.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,261XG@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
WLSH2_k127_2996890_9	926569.ANT_31030	2.472e-116	382.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WLSH2_k127_2996890_13	926569.ANT_31020	4.252e-76	260.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi	200795|Chloroflexi	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WLSH2_k127_2996890_11	926569.ANT_31010	3.647e-102	338.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH2_k127_2996890_12	926569.ANT_03510	6.881e-79	267.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WLSH2_k127_2996890_10	926569.ANT_03500	1.451e-110	363.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WLSH2_k127_2996890_14	926569.ANT_03490	3.28e-63	228.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WLSH2_k127_2996890_7	926569.ANT_02050	1.331e-135	438.0	COG1494@1|root,COG1494@2|Bacteria,2G5XR@200795|Chloroflexi	200795|Chloroflexi	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
WLSH2_k127_3050884_1	1123023.JIAI01000020_gene2106	1.903e-86	297.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,4E076@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
WLSH2_k127_3050884_0	861299.J421_1510	1.459e-171	553.0	COG0154@1|root,COG0154@2|Bacteria,1ZT8R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
WLSH2_k127_3050884_3	1128421.JAGA01000002_gene1382	2.854e-45	168.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_3050884_5	56110.Oscil6304_4466	9.484e-39	151.0	COG5433@1|root,COG5433@2|Bacteria,1G2IT@1117|Cyanobacteria,1HHU1@1150|Oscillatoriales	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_3050884_6	102129.Lepto7375DRAFT_5666	2.462e-11	67.0	COG5433@1|root,COG5433@2|Bacteria,1G2IT@1117|Cyanobacteria,1HHU1@1150|Oscillatoriales	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_3050884_8	313606.M23134_05930	0.0006341	44.0	COG0732@1|root,COG0732@2|Bacteria,4NK11@976|Bacteroidetes,47QR3@768503|Cytophagia	976|Bacteroidetes	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
WLSH2_k127_3050884_2	345341.KUTG_08651	2.511e-47	182.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4E37Q@85010|Pseudonocardiales	201174|Actinobacteria	Q	Poly(3-hydroxybutyrate) depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
WLSH2_k127_3050884_4	1128421.JAGA01000001_gene2240	3.964e-39	160.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF285,LolA,MucB_RseB,NHL
WLSH2_k127_3050884_7	1123009.AUID01000012_gene1653	1.211e-09	60.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,268T7@186813|unclassified Clostridiales	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_3084947_22	158787.BSCA_2328	4.607e-06	55.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CZ69@85004|Bifidobacteriales	201174|Actinobacteria	D	recombinase XerD	xerD	GO:0008150,GO:0040007	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WLSH2_k127_3084947_5	383372.Rcas_4135	2.934e-125	418.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,PAS_9,Response_reg
WLSH2_k127_3084947_3	926569.ANT_04770	8.209e-182	608.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
WLSH2_k127_3084947_10	338963.Pcar_2439	1.11e-67	240.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WLSH2_k127_3084947_8	926569.ANT_05870	6.862e-80	271.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	pilL	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K02487,ko:K03407,ko:K03413,ko:K06596,ko:K11526,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507,M00508,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
WLSH2_k127_3084947_6	1128421.JAGA01000001_gene2047	4.269e-110	364.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WLSH2_k127_3084947_7	319795.Dgeo_1614	6.772e-91	320.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HisKA_7TM,PAS,PAS_4,PAS_8
WLSH2_k127_3084947_4	926569.ANT_24850	1.921e-164	527.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WLSH2_k127_3084947_20	1304878.AUGD01000001_gene422	5.26e-17	89.0	COG4552@1|root,COG4552@2|Bacteria,1MVCP@1224|Proteobacteria,2TT6Z@28211|Alphaproteobacteria,3JR0T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WLSH2_k127_3084947_1	926569.ANT_22400	3.407e-232	735.0	COG3533@1|root,COG3533@2|Bacteria,2G7X9@200795|Chloroflexi	200795|Chloroflexi	S	COGs COG3533 conserved	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
WLSH2_k127_3084947_14	485913.Krac_4807	3.057e-45	169.0	COG1670@1|root,COG1670@2|Bacteria,2G7IT@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH2_k127_3084947_12	1499967.BAYZ01000193_gene3904	2.02e-47	178.0	2AR01@1|root,31G8U@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3084947_0	485913.Krac_7358	1.02e-273	855.0	COG1472@1|root,COG1472@2|Bacteria,2G84T@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WLSH2_k127_3084947_18	1131269.AQVV01000020_gene2197	1.64e-23	107.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	DinB_2,Methyltransf_23,Methyltransf_25
WLSH2_k127_3084947_11	1125863.JAFN01000001_gene122	1.686e-55	210.0	COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_3084947_17	926569.ANT_27650	9.797e-26	110.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WLSH2_k127_3084947_2	926550.CLDAP_11620	2.353e-185	586.0	COG0446@1|root,COG0446@2|Bacteria,2G6GM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_3084947_19	1191523.MROS_1024	1.228e-21	102.0	COG2427@1|root,COG2427@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1641
WLSH2_k127_3084947_13	926569.ANT_27630	4.125e-46	168.0	COG2920@1|root,COG2920@2|Bacteria,2G9BI@200795|Chloroflexi	200795|Chloroflexi	P	DsrC like protein	dsrC	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
WLSH2_k127_3084947_9	926569.ANT_27620	8.875e-79	265.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
WLSH2_k127_3084947_16	926569.ANT_00160	1.114e-38	151.0	28U8H@1|root,2ZGE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3084947_15	926550.CLDAP_06330	2.089e-41	160.0	COG2606@1|root,COG2606@2|Bacteria,2G931@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
WLSH2_k127_3097453_11	177437.HRM2_44710	8.817e-17	81.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3097453_10	56780.SYN_01286	5.455e-43	163.0	COG1913@1|root,COG1913@2|Bacteria,1N38I@1224|Proteobacteria,42UMZ@68525|delta/epsilon subdivisions,2WRS9@28221|Deltaproteobacteria,2MS0H@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
WLSH2_k127_3097453_4	224325.AF_2278	9.607e-101	339.0	COG1180@1|root,arCOG00947@2157|Archaea,2XWY1@28890|Euryarchaeota	28890|Euryarchaeota	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
WLSH2_k127_3097453_8	880073.Calab_1912	3.628e-62	223.0	COG2518@1|root,COG2518@2|Bacteria,2NP7E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WLSH2_k127_3097453_3	1047013.AQSP01000124_gene2683	1.362e-117	409.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
WLSH2_k127_3097453_12	926569.ANT_09040	1.757e-07	62.0	COG0265@1|root,COG0265@2|Bacteria,2G821@200795|Chloroflexi	200795|Chloroflexi	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
WLSH2_k127_3097453_0	671143.DAMO_0407	3.093e-255	802.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_3097453_7	1235457.C404_25045	3.14e-71	248.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,1K29G@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_3097453_5	525904.Tter_2095	2.732e-75	271.0	COG0642@1|root,COG2205@2|Bacteria,2NQXV@2323|unclassified Bacteria	2|Bacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA
WLSH2_k127_3097453_2	926569.ANT_08100	8.327e-128	415.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
WLSH2_k127_3097453_1	926569.ANT_08110	3.45e-205	647.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WLSH2_k127_3097453_6	926569.ANT_17350	8.408e-72	253.0	COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
WLSH2_k127_3097453_9	1235279.C772_01025	1.513e-59	217.0	COG3375@1|root,COG3375@2|Bacteria,1V21D@1239|Firmicutes,4HG3H@91061|Bacilli,26EU3@186818|Planococcaceae	91061|Bacilli	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_3127155_2	1033743.CAES01000080_gene3874	8.247e-67	228.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,26UCG@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
WLSH2_k127_3127155_4	926569.ANT_19290	1.388e-60	218.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3127155_1	926569.ANT_19280	9.42e-95	316.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WLSH2_k127_3127155_3	326427.Cagg_3772	1.014e-66	249.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
WLSH2_k127_3127155_0	926550.CLDAP_03690	2.975e-117	383.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WLSH2_k127_3198028_15	1134474.O59_002851	4.753e-09	60.0	2BK9M@1|root,32EPT@2|Bacteria,1NC6I@1224|Proteobacteria,1SV8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3198028_0	443143.GM18_0105	0.0	1062.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QGH@68525|delta/epsilon subdivisions,2WKTM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM multicopper oxidase type 2	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
WLSH2_k127_3198028_2	670487.Ocepr_0187	6.767e-89	304.0	COG4948@1|root,COG4948@2|Bacteria,1WMNA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Mandelate racemase muconate lactonizing enzyme	ykfB	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_3198028_11	926556.Echvi_1589	9.841e-32	134.0	COG0596@1|root,COG0596@2|Bacteria,4NJSG@976|Bacteroidetes,47XXP@768503|Cytophagia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,CarbopepD_reg_2
WLSH2_k127_3198028_12	316274.Haur_3592	1.868e-31	136.0	COG0791@1|root,COG0791@2|Bacteria,2G99E@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
WLSH2_k127_3198028_6	105559.Nwat_1866	2.137e-77	261.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,1S3N1@1236|Gammaproteobacteria,1X23J@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WLSH2_k127_3198028_7	324602.Caur_0188	2.725e-75	256.0	COG0693@1|root,COG0693@2|Bacteria,2GAQG@200795|Chloroflexi,375Y9@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ThiJ PfpI domain protein	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WLSH2_k127_3198028_5	1499967.BAYZ01000013_gene6463	6.432e-81	278.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
WLSH2_k127_3198028_4	1128421.JAGA01000002_gene971	4.525e-81	277.0	COG2309@1|root,COG2309@2|Bacteria,2NPEI@2323|unclassified Bacteria	2|Bacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WLSH2_k127_3198028_10	1128421.JAGA01000002_gene971	2.797e-32	126.0	COG2309@1|root,COG2309@2|Bacteria,2NPEI@2323|unclassified Bacteria	2|Bacteria	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WLSH2_k127_3198028_1	926569.ANT_22520	1.083e-260	818.0	COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WLSH2_k127_3198028_9	926569.ANT_22530	5.06e-49	183.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
WLSH2_k127_3198028_8	765420.OSCT_3068	1.839e-74	264.0	COG2339@1|root,COG2339@2|Bacteria,2G946@200795|Chloroflexi,375Y0@32061|Chloroflexia	32061|Chloroflexia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
WLSH2_k127_3198028_14	1395513.P343_06705	2.139e-09	69.0	COG3103@1|root,COG3807@1|root,COG4193@1|root,COG3103@2|Bacteria,COG3807@2|Bacteria,COG4193@2|Bacteria,1V0NC@1239|Firmicutes,4HNGM@91061|Bacilli	91061|Bacilli	GT	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3
WLSH2_k127_3230085_2	926569.ANT_09830	2.061e-118	401.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,GGDEF,HATPase_c,HD,HD_5,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WLSH2_k127_3230085_4	926569.ANT_09820	1.052e-95	332.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G97C@200795|Chloroflexi	200795|Chloroflexi	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WLSH2_k127_3230085_0	926569.ANT_09810	2.043e-132	430.0	COG2008@1|root,COG2008@2|Bacteria,2G5XG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	gly1	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WLSH2_k127_3230085_1	926569.ANT_09800	1.034e-125	408.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH2_k127_3230085_6	926569.ANT_09790	2.483e-41	158.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi	200795|Chloroflexi	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WLSH2_k127_3230085_3	1191523.MROS_0930	1.019e-110	368.0	COG0787@1|root,COG0787@2|Bacteria	2|Bacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WLSH2_k127_3230085_7	1123242.JH636434_gene4709	1.145e-30	123.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH2_k127_3230085_5	357808.RoseRS_2402	2.037e-92	331.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4
WLSH2_k127_3230085_10	446462.Amir_2207	0.0001261	49.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4E8P4@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_3230085_9	326427.Cagg_2731	7.68e-06	53.0	COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi,376RT@32061|Chloroflexia	32061|Chloroflexia	M	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
WLSH2_k127_3232198_22	1123371.ATXH01000005_gene2092	2.374e-07	61.0	COG0517@1|root,COG0517@2|Bacteria,2GI21@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_3232198_21	1454004.AW11_01670	6.708e-20	99.0	COG0604@1|root,COG2905@1|root,COG0604@2|Bacteria,COG2905@2|Bacteria,1MXIK@1224|Proteobacteria,2W1P8@28216|Betaproteobacteria	28216|Betaproteobacteria	CT	Domain in cystathionine beta-synthase and other proteins.	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,CBS
WLSH2_k127_3232198_17	266117.Rxyl_0771	2.675e-42	166.0	arCOG06048@1|root,31EJQ@2|Bacteria,2GPSC@201174|Actinobacteria,4CQDB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3232198_14	338963.Pcar_0940	6.737e-54	199.0	COG1349@1|root,COG1349@2|Bacteria,1MXW2@1224|Proteobacteria,42VAF@68525|delta/epsilon subdivisions,2WRBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	DeoR C terminal sensor domain	-	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
WLSH2_k127_3232198_9	1380390.JIAT01000009_gene1063	9.611e-84	289.0	COG2129@1|root,COG2129@2|Bacteria,2IJW1@201174|Actinobacteria,4CQ37@84995|Rubrobacteria	84995|Rubrobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3232198_15	309801.trd_1316	1.565e-46	189.0	COG0531@1|root,COG0531@2|Bacteria,2G76Z@200795|Chloroflexi	200795|Chloroflexi	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_3232198_10	1298863.AUEP01000004_gene2240	1.856e-81	280.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4DU8X@85009|Propionibacteriales	201174|Actinobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
WLSH2_k127_3232198_0	1380391.JIAS01000015_gene369	1.158e-189	620.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2JREU@204441|Rhodospirillales	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
WLSH2_k127_3232198_7	41431.PCC8801_0885	1.666e-87	301.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.1.1.72,2.7.1.15,2.7.1.4	ko:K00571,ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000,ko02048	-	-	-	PfkB
WLSH2_k127_3232198_2	635013.TherJR_0057	2.622e-180	576.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_3232198_16	706587.Desti_4215	1.861e-44	169.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
WLSH2_k127_3232198_23	749927.AMED_1225	0.0002311	48.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
WLSH2_k127_3232198_13	522306.CAP2UW1_2085	4.56e-71	248.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,1KQA5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	phosphate transporter	-	-	-	ko:K03306,ko:K16322	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.1	-	-	PHO4
WLSH2_k127_3232198_4	316274.Haur_2471	2.331e-129	424.0	COG1840@1|root,COG1840@2|Bacteria,2G65V@200795|Chloroflexi,376WG@32061|Chloroflexia	32061|Chloroflexia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
WLSH2_k127_3232198_6	926569.ANT_31320	9.327e-106	351.0	COG4132@1|root,COG4132@2|Bacteria,2G69Y@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
WLSH2_k127_3232198_8	511051.CSE_14420	1.288e-86	293.0	COG1177@1|root,COG1177@2|Bacteria	2|Bacteria	P	DNA import into cell involved in transformation	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
WLSH2_k127_3232198_5	1381123.AYOD01000043_gene1446	2.82e-127	417.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,43GT7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
WLSH2_k127_3232198_11	1280390.CBQR020000003_gene47	1.086e-76	266.0	COG1524@1|root,COG1524@2|Bacteria,1TR0T@1239|Firmicutes,4HD1Y@91061|Bacilli,26UHQ@186822|Paenibacillaceae	91061|Bacilli	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WLSH2_k127_3232198_12	316274.Haur_1216	1.643e-71	252.0	COG0454@1|root,COG0456@2|Bacteria,2G9FH@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_3232198_20	316274.Haur_1215	7.71e-31	126.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K02030,ko:K03407,ko:K07679,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,ko05133,map02020,map02030,map04112,map05133	M00236,M00477,M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	3.A.1.3	-	-	CHASE3,HATPase_c,HisKA,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
WLSH2_k127_3232198_3	926569.ANT_19900	7.727e-141	457.0	COG0498@1|root,COG0498@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_3232198_18	316274.Haur_1219	4.661e-38	146.0	COG0784@1|root,COG0784@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	2|Bacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WLSH2_k127_3232198_19	316274.Haur_1219	1.286e-31	128.0	COG0784@1|root,COG0784@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	2|Bacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WLSH2_k127_3232198_1	316274.Haur_1218	1.997e-185	588.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733,ko:K22010	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018,M00839	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	HATPase_c,HisKA,PALP,Response_reg
WLSH2_k127_3308781_13	926569.ANT_19020	2.668e-16	78.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi	200795|Chloroflexi	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
WLSH2_k127_3308781_7	926569.ANT_10030	4.274e-54	190.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi	200795|Chloroflexi	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
WLSH2_k127_3308781_1	926569.ANT_10040	1.139e-103	339.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
WLSH2_k127_3308781_4	926569.ANT_10050	5.071e-82	278.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
WLSH2_k127_3308781_11	926569.ANT_10060	2.005e-31	127.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi	200795|Chloroflexi	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
WLSH2_k127_3308781_0	926569.ANT_10070	1.159e-144	464.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WLSH2_k127_3308781_8	926569.ANT_10080	1.398e-45	165.0	COG0185@1|root,COG0185@2|Bacteria,2G6US@200795|Chloroflexi	200795|Chloroflexi	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
WLSH2_k127_3308781_10	926569.ANT_10090	1.493e-38	146.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi	200795|Chloroflexi	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
WLSH2_k127_3308781_2	926569.ANT_10100	1.769e-95	320.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi	200795|Chloroflexi	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WLSH2_k127_3308781_5	926569.ANT_10110	5.219e-67	230.0	COG0197@1|root,COG0197@2|Bacteria,2G6NA@200795|Chloroflexi	200795|Chloroflexi	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
WLSH2_k127_3308781_14	926569.ANT_10120	1.797e-10	64.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
WLSH2_k127_3308781_12	926569.ANT_10130	1.124e-30	123.0	COG0186@1|root,COG0186@2|Bacteria,2G722@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
WLSH2_k127_3308781_6	926569.ANT_10140	4.315e-62	214.0	COG0093@1|root,COG0093@2|Bacteria,2G6MZ@200795|Chloroflexi	200795|Chloroflexi	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
WLSH2_k127_3308781_9	926569.ANT_10150	1.301e-40	152.0	COG0198@1|root,COG0198@2|Bacteria,2G750@200795|Chloroflexi	200795|Chloroflexi	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
WLSH2_k127_3308781_3	926569.ANT_10160	3.219e-84	281.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi	200795|Chloroflexi	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
WLSH2_k127_3332311_20	1469607.KK073768_gene4663	2.089e-17	82.0	COG3547@1|root,COG3547@2|Bacteria,1GA7N@1117|Cyanobacteria,1HTM7@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
WLSH2_k127_3332311_17	485913.Krac_3951	4.805e-34	133.0	COG3666@1|root,COG3666@2|Bacteria,2G998@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
WLSH2_k127_3332311_21	485913.Krac_3951	3.321e-09	59.0	COG3666@1|root,COG3666@2|Bacteria,2G998@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
WLSH2_k127_3332311_12	485913.Krac_3951	4.207e-70	246.0	COG3666@1|root,COG3666@2|Bacteria,2G998@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
WLSH2_k127_3332311_18	316274.Haur_3574	6.413e-30	129.0	291JP@1|root,2ZP62@2|Bacteria,2GASU@200795|Chloroflexi,3778Y@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3332311_16	1128421.JAGA01000002_gene855	7.601e-37	145.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
WLSH2_k127_3332311_19	485913.Krac_9920	6.487e-22	97.0	COG0695@1|root,COG0695@2|Bacteria,2G75B@200795|Chloroflexi	200795|Chloroflexi	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
WLSH2_k127_3332311_5	926569.ANT_18360	2.698e-139	449.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH2_k127_3332311_9	926569.ANT_18350	4.697e-97	332.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WLSH2_k127_3332311_11	349124.Hhal_0136	4.206e-93	315.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,1RR31@1236|Gammaproteobacteria,1WXBJ@135613|Chromatiales	135613|Chromatiales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH2_k127_3332311_8	930171.Asphe3_09660	1.795e-102	342.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WLSH2_k127_3332311_3	926569.ANT_18090	1.786e-147	472.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi	200795|Chloroflexi	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH2_k127_3332311_1	926569.ANT_18100	7.127e-218	680.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
WLSH2_k127_3332311_10	330214.NIDE1244	2.77e-93	318.0	COG0686@1|root,COG0686@2|Bacteria	2|Bacteria	E	alanine dehydrogenase activity	ald	GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
WLSH2_k127_3332311_2	1232410.KI421419_gene2455	2.501e-202	637.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,43UGV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
WLSH2_k127_3332311_7	215803.DB30_5889	5.867e-130	431.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,2YUEU@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WLSH2_k127_3332311_14	1444309.JAQG01000157_gene3282	1.38e-55	205.0	COG0697@1|root,COG0697@2|Bacteria,1UH2I@1239|Firmicutes,4HCFV@91061|Bacilli,26TFQ@186822|Paenibacillaceae	91061|Bacilli	EG	membrane	gmT1	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_3332311_15	247490.KSU1_C0604	1.68e-43	164.0	COG1186@1|root,COG1186@2|Bacteria,2J05G@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
WLSH2_k127_3332311_4	926569.ANT_18140	1.164e-144	468.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi	200795|Chloroflexi	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
WLSH2_k127_3332311_0	926569.ANT_18150	8.23e-245	771.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WLSH2_k127_3332311_13	926569.ANT_18160	1.906e-69	242.0	COG2186@1|root,COG2186@2|Bacteria,2G8XU@200795|Chloroflexi	200795|Chloroflexi	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD
WLSH2_k127_3332311_6	309801.trd_0392	1.265e-130	428.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi,27Y2Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WLSH2_k127_3348140_1	1229172.JQFA01000002_gene2146	4.923e-65	242.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_3348140_0	610130.Closa_1338	5.14e-181	591.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1UYA0@1239|Firmicutes	1239|Firmicutes	GT	Phosphoenolpyruvate synthase	yvkC	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_3382003_3	926569.ANT_30330	4.92e-210	677.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
WLSH2_k127_3382003_2	552811.Dehly_0095	4.344e-218	709.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,34CQM@301297|Dehalococcoidia	301297|Dehalococcoidia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WLSH2_k127_3382003_5	926569.ANT_30350	3.195e-65	243.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3382003_4	926569.ANT_04320	1.885e-115	377.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH2_k127_3382003_6	926569.ANT_04330	2.65e-54	198.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH2_k127_3382003_10	926569.ANT_04340	1.826e-22	103.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	mec	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
WLSH2_k127_3382003_1	1007103.AFHW01000171_gene2574	6.686e-247	777.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,26R74@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WLSH2_k127_3382003_0	926569.ANT_25700	0.0	1149.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WLSH2_k127_3382003_9	926569.ANT_25690	6.766e-36	146.0	COG3287@1|root,COG3287@2|Bacteria,2G7G0@200795|Chloroflexi	200795|Chloroflexi	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
WLSH2_k127_345344_20	357808.RoseRS_0489	7.267e-43	158.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi,37571@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WLSH2_k127_345344_9	1121405.dsmv_1496	1.478e-108	366.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42RH4@68525|delta/epsilon subdivisions,2WNQ0@28221|Deltaproteobacteria,2MNDR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
WLSH2_k127_345344_12	357808.RoseRS_0169	4.048e-94	315.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi,3764I@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
WLSH2_k127_345344_15	357808.RoseRS_0170	4.123e-78	269.0	COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi,37758@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
WLSH2_k127_345344_5	357808.RoseRS_0174	5.18e-125	407.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi,376DK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
WLSH2_k127_345344_22	926569.ANT_12680	1.341e-36	143.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WLSH2_k127_345344_1	926569.ANT_04130	1.046e-145	481.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
WLSH2_k127_345344_30	65393.PCC7424_5869	1.665e-14	83.0	2CGDF@1|root,34388@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_345344_25	926569.ANT_29210	3.913e-34	149.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WLSH2_k127_345344_4	926569.ANT_06580	3.52e-125	406.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
WLSH2_k127_345344_11	926569.ANT_06560	4.133e-101	347.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
WLSH2_k127_345344_7	926569.ANT_06540	4.53e-113	374.0	COG1215@1|root,COG1215@2|Bacteria,2G8MG@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_345344_10	926569.ANT_06530	3.932e-101	336.0	COG2604@1|root,COG2604@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,DUF2920,MAF_flag10
WLSH2_k127_345344_8	926569.ANT_06520	8.03e-109	357.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WLSH2_k127_345344_2	926569.ANT_06500	2.841e-145	471.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_345344_14	926569.ANT_06490	2.819e-88	296.0	COG1083@1|root,COG1083@2|Bacteria	2|Bacteria	M	cytidylyl-transferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,RraA-like
WLSH2_k127_345344_13	1449063.JMLS01000021_gene835	2.415e-88	299.0	COG3541@1|root,COG3541@2|Bacteria,1TT57@1239|Firmicutes,4HD38@91061|Bacilli,26RAT@186822|Paenibacillaceae	91061|Bacilli	S	Predicted nucleotidyltransferase	ycgL	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
WLSH2_k127_345344_24	574376.BAMA_03785	7.756e-35	141.0	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4IQ7V@91061|Bacilli,1ZQWI@1386|Bacillus	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_345344_27	324057.Pjdr2_2017	2.475e-27	118.0	COG1051@1|root,COG1051@2|Bacteria,1V6PH@1239|Firmicutes,4IQ1N@91061|Bacilli,27665@186822|Paenibacillaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_345344_21	357808.RoseRS_4364	7.761e-38	153.0	28I6Y@1|root,2Z89T@2|Bacteria	2|Bacteria	S	SseB protein C-terminal domain	sseB	-	-	-	-	-	-	-	-	-	-	-	SseB,SseB_C
WLSH2_k127_345344_3	926569.ANT_17710	2.797e-136	439.0	COG1216@1|root,COG1216@2|Bacteria,2G961@200795|Chloroflexi	200795|Chloroflexi	H	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_345344_17	886293.Sinac_7569	5.637e-59	225.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
WLSH2_k127_345344_0	1047013.AQSP01000144_gene895	1.113e-170	550.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
WLSH2_k127_345344_26	1385935.N836_35615	6.17e-34	141.0	COG0457@1|root,COG0457@2|Bacteria,1GAAM@1117|Cyanobacteria,1HDEW@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
WLSH2_k127_345344_28	264732.Moth_0652	3.864e-21	98.0	COG1569@1|root,COG1569@2|Bacteria,1V6UC@1239|Firmicutes,24KEA@186801|Clostridia,42HGV@68295|Thermoanaerobacterales	186801|Clostridia	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
WLSH2_k127_345344_18	1121374.KB891585_gene2413	1.045e-53	195.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WLSH2_k127_345344_6	926569.ANT_14150	8.178e-125	409.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16,5.3.1.8,5.3.1.9	ko:K00820,ko:K15916	ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931	M00001,M00004,M00114	R00768,R01819,R02739,R02740,R03321	RC00010,RC00163,RC00376,RC00563,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	SIS
WLSH2_k127_345344_29	3218.PP1S80_148V6.1	2.47e-17	98.0	KOG4351@1|root,KOG4582@1|root,KOG4351@2759|Eukaryota,KOG4582@2759|Eukaryota,37HVT@33090|Viridiplantae,3GCJ1@35493|Streptophyta	35493|Streptophyta	V	ubiquitin binding	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1,ZZ
WLSH2_k127_345344_16	926569.ANT_22190	2.069e-74	285.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_345344_19	1382306.JNIM01000001_gene3604	2.716e-47	197.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
WLSH2_k127_3458544_1	1173020.Cha6605_0968	8.912e-136	446.0	COG2267@1|root,COG2267@2|Bacteria,1G771@1117|Cyanobacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
WLSH2_k127_3458544_4	797210.Halxa_0140	2.003e-42	169.0	arCOG13341@1|root,arCOG13341@2157|Archaea,2XXWE@28890|Euryarchaeota,23WKG@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3458544_3	573413.Spirs_4186	2.336e-49	191.0	COG1835@1|root,COG1835@2|Bacteria,2J8VJ@203691|Spirochaetes	203691|Spirochaetes	I	PFAM Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WLSH2_k127_3458544_5	571.MC52_15565	1.883e-39	152.0	COG1943@1|root,COG1943@2|Bacteria,1RAP9@1224|Proteobacteria,1S230@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
WLSH2_k127_3458544_7	33876.JNXY01000002_gene258	2.04e-11	67.0	COG1266@1|root,COG1266@2|Bacteria,2GMJ1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_3458544_2	471852.Tcur_4825	7.217e-80	274.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_25
WLSH2_k127_3458544_0	42256.RradSPS_0358	2.913e-145	500.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_3458544_6	1128421.JAGA01000001_gene2283	2.394e-23	105.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WLSH2_k127_3475770_3	933262.AXAM01000028_gene3342	6.123e-08	56.0	COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,42WFU@68525|delta/epsilon subdivisions,2WS4T@28221|Deltaproteobacteria,2MKX1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_3475770_0	485913.Krac_1500	4.642e-80	275.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	ko:K02529,ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022,ko03000	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,TniQ
WLSH2_k127_3475770_1	749414.SBI_02612	1.695e-71	260.0	COG1233@1|root,COG1233@2|Bacteria,2GP0A@201174|Actinobacteria	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
WLSH2_k127_3475770_2	857087.Metme_4171	2.03e-70	256.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria,1XDYA@135618|Methylococcales	135618|Methylococcales	Q	Flavin containing amine oxidoreductase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
WLSH2_k127_348645_6	1131462.DCF50_p622	2.359e-50	186.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,26246@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_348645_1	926569.ANT_07430	7.702e-117	387.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
WLSH2_k127_348645_4	264732.Moth_1000	6.843e-65	238.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,42FN6@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WLSH2_k127_348645_3	1183438.GKIL_3985	4.897e-73	254.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
WLSH2_k127_348645_2	706587.Desti_5093	3.098e-80	303.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_348645_0	926569.ANT_25100	8.04e-233	736.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
WLSH2_k127_348645_5	926569.ANT_25090	7.907e-59	214.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3494982_44	1304885.AUEY01000093_gene1590	0.0009174	44.0	COG3177@1|root,COG3177@2|Bacteria,1MX0V@1224|Proteobacteria,42RKK@68525|delta/epsilon subdivisions,2WNV3@28221|Deltaproteobacteria,2MK5P@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
WLSH2_k127_3494982_9	926569.ANT_11740	6.433e-135	448.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G6UY@200795|Chloroflexi	200795|Chloroflexi	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_3494982_25	760568.Desku_2954	2.406e-50	205.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,24A78@186801|Clostridia,262GC@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_3494982_5	926569.ANT_16920	2.665e-194	616.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
WLSH2_k127_3494982_16	1128421.JAGA01000001_gene2396	4.627e-87	300.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WLSH2_k127_3494982_11	926569.ANT_16940	1.902e-123	407.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WLSH2_k127_3494982_4	926569.ANT_16960	1.2e-195	619.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WLSH2_k127_3494982_13	926569.ANT_04560	6.903e-105	347.0	COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi	200795|Chloroflexi	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WLSH2_k127_3494982_18	926569.ANT_04550	3e-76	262.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
WLSH2_k127_3494982_28	926569.ANT_04540	1.146e-39	150.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WLSH2_k127_3494982_27	604331.AUHY01000042_gene2025	1.764e-41	162.0	COG0406@1|root,COG0406@2|Bacteria,1WMWI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WLSH2_k127_3494982_10	221360.RS9917_05080	1.004e-133	437.0	COG0304@1|root,COG0304@2|Bacteria,1G1J5@1117|Cyanobacteria,1GZS9@1129|Synechococcus	1117|Cyanobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH2_k127_3494982_22	926569.ANT_22470	2.139e-63	222.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
WLSH2_k127_3494982_34	926569.ANT_22470	3.361e-17	83.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
WLSH2_k127_3494982_24	926569.ANT_22480	2.05e-58	208.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
WLSH2_k127_3494982_20	926569.ANT_22490	3.908e-69	243.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WLSH2_k127_3494982_35	986075.CathTA2_2041	6.23e-13	73.0	COG5652@1|root,COG5652@2|Bacteria,1VGDJ@1239|Firmicutes,4HNZ0@91061|Bacilli	91061|Bacilli	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WLSH2_k127_3494982_7	459495.SPLC1_S020090	3.675e-168	547.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1G2KN@1117|Cyanobacteria,1HBXR@1150|Oscillatoriales	1117|Cyanobacteria	EH	Amino-transferase class IV	-	-	2.6.1.85,4.1.3.38	ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
WLSH2_k127_3494982_2	290317.Cpha266_0842	6.178e-210	667.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_3494982_1	1304875.JAFZ01000002_gene325	2.638e-224	710.0	COG1132@1|root,COG1132@2|Bacteria,3TA8S@508458|Synergistetes	508458|Synergistetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WLSH2_k127_3494982_36	1006006.Mcup_1526	7.908e-13	74.0	COG0221@1|root,arCOG01711@2157|Archaea,2XQB5@28889|Crenarchaeota	28889|Crenarchaeota	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
WLSH2_k127_3494982_15	1347369.CCAD010000087_gene1866	3.692e-94	319.0	COG0656@1|root,COG0656@2|Bacteria,1TSG5@1239|Firmicutes,4HAMT@91061|Bacilli,1ZEPD@1386|Bacillus	91061|Bacilli	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_3494982_42	714943.Mucpa_4703	0.0006215	44.0	COG1331@1|root,COG1331@2|Bacteria,4NFE2@976|Bacteroidetes,1IQ72@117747|Sphingobacteriia	976|Bacteroidetes	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
WLSH2_k127_3494982_32	402777.KB235904_gene3578	1.19e-24	114.0	COG3860@1|root,COG3860@2|Bacteria,1GBAQ@1117|Cyanobacteria	1117|Cyanobacteria	S	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
WLSH2_k127_3494982_3	926569.ANT_11410	4.668e-209	671.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
WLSH2_k127_3494982_26	391596.PBAL39_09901	6.534e-44	167.0	COG1285@1|root,COG1285@2|Bacteria,4NRHK@976|Bacteroidetes,1ITN7@117747|Sphingobacteriia	976|Bacteroidetes	S	Magnesium transporter MgtC	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
WLSH2_k127_3494982_12	926550.CLDAP_06710	1.831e-119	394.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WLSH2_k127_3494982_8	1356854.N007_03230	1.613e-156	503.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH2_k127_3494982_14	926569.ANT_20880	2.428e-98	335.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_3494982_19	926569.ANT_20860	9.573e-74	252.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WLSH2_k127_3494982_23	926569.ANT_18330	1.338e-61	217.0	COG0521@1|root,COG0521@2|Bacteria,2G7HV@200795|Chloroflexi	200795|Chloroflexi	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
WLSH2_k127_3494982_30	504728.K649_02050	7.331e-29	121.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	ypeA	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
WLSH2_k127_3494982_31	926569.ANT_18320	8.84e-25	108.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K03413,ko:K07719	ko02020,ko02030,map02020,map02030	M00506,M00518	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HATPase_c,Response_reg,YcbB
WLSH2_k127_3494982_0	926569.ANT_18310	0.0	1137.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WLSH2_k127_3494982_33	926569.ANT_18300	1.77e-23	104.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
WLSH2_k127_3494982_17	485913.Krac_2203	2.678e-76	269.0	COG3677@1|root,COG3677@2|Bacteria,2G6SJ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3494982_41	1121448.DGI_3055	2.399e-05	50.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MB2S@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WLSH2_k127_3494982_21	592015.HMPREF1705_01827	3.278e-68	242.0	COG0697@1|root,COG0697@2|Bacteria,3TB45@508458|Synergistetes	508458|Synergistetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_3494982_43	891968.Anamo_0049	0.0007318	42.0	COG0697@1|root,COG0697@2|Bacteria,3TB45@508458|Synergistetes	508458|Synergistetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_3494982_6	926569.ANT_20720	7.683e-176	557.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
WLSH2_k127_3509978_0	383372.Rcas_1300	1.923e-234	760.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WLSH2_k127_3509978_3	1239962.C943_04385	3.583e-10	67.0	COG1051@1|root,COG1051@2|Bacteria,4NN73@976|Bacteroidetes,47P7Y@768503|Cytophagia	976|Bacteroidetes	F	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WLSH2_k127_3509978_2	324602.Caur_1140	2.115e-39	162.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GGDEF,HAMP
WLSH2_k127_3509978_1	926550.CLDAP_29080	2.69e-184	607.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
WLSH2_k127_3514319_2	926569.ANT_00050	3.722e-109	357.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_3514319_6	1340493.JNIF01000004_gene1024	6.765e-19	101.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
WLSH2_k127_3514319_4	1120956.JHZK01000007_gene2813	3.46e-25	110.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2VAAS@28211|Alphaproteobacteria,1JQG0@119043|Rhodobiaceae	28211|Alphaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WLSH2_k127_3514319_3	522306.CAP2UW1_0547	2.299e-55	200.0	COG0500@1|root,COG0500@2|Bacteria,1R0QC@1224|Proteobacteria,2WHV7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3514319_1	1128421.JAGA01000002_gene1768	6.074e-113	377.0	COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria	2|Bacteria	C	e3 binding domain	bfmBB	-	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WLSH2_k127_3514319_7	383372.Rcas_4353	6.461e-13	70.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH2_k127_3514319_5	1396418.BATQ01000056_gene247	1.638e-21	95.0	COG0614@1|root,COG0614@2|Bacteria,46W5F@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH2_k127_3514319_0	1124780.ANNU01000044_gene525	2.393e-304	953.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WLSH2_k127_3540621_3	586413.CCDL010000001_gene1218	7.008e-55	201.0	COG1680@1|root,COG1680@2|Bacteria,1V3KP@1239|Firmicutes,4IDK5@91061|Bacilli,23KW4@182709|Oceanobacillus	91061|Bacilli	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_3540621_6	316274.Haur_2144	2.963e-13	77.0	COG0784@1|root,COG0784@2|Bacteria,2GB7B@200795|Chloroflexi,377HM@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WLSH2_k127_3540621_2	926569.ANT_11780	2.189e-58	221.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WLSH2_k127_3540621_7	716544.wcw_1307	1.263e-10	66.0	2EAAF@1|root,334ES@2|Bacteria,2JGCU@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3540621_5	1408433.JHXV01000028_gene2136	4.403e-29	125.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,1I1B3@117743|Flavobacteriia,2PB9Y@246874|Cryomorphaceae	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
WLSH2_k127_3540621_0	357808.RoseRS_1075	1.22e-148	499.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_3540621_1	357808.RoseRS_3212	1.194e-123	407.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
WLSH2_k127_3540621_4	926569.ANT_07670	1.931e-39	156.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH2_k127_3543374_5	926569.ANT_06330	3.037e-74	255.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_3543374_6	485913.Krac_7960	3.095e-70	247.0	COG0500@1|root,COG2226@2|Bacteria,2G78Q@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_3543374_1	926569.ANT_06340	1.108e-160	512.0	COG1086@1|root,COG1086@2|Bacteria,2G8BP@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
WLSH2_k127_3543374_4	926569.ANT_06350	1.924e-85	292.0	COG1091@1|root,COG1091@2|Bacteria,2G9A2@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WLSH2_k127_3543374_7	573061.Clocel_3479	1.605e-52	190.0	COG0494@1|root,COG0494@2|Bacteria,1V5CY@1239|Firmicutes,24HM6@186801|Clostridia,36MGF@31979|Clostridiaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WLSH2_k127_3543374_8	1321778.HMPREF1982_03438	2.403e-51	186.0	COG0537@1|root,COG0537@2|Bacteria,1VSAZ@1239|Firmicutes,24IYZ@186801|Clostridia	186801|Clostridia	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WLSH2_k127_3543374_11	1089548.KI783301_gene2104	1.16e-18	94.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,4HFNQ@91061|Bacilli,3WE7Z@539002|Bacillales incertae sedis	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	yqiK	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WLSH2_k127_3543374_0	926569.ANT_06360	1e-160	513.0	COG2089@1|root,COG2089@2|Bacteria,2G8PB@200795|Chloroflexi	200795|Chloroflexi	M	SAF	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
WLSH2_k127_3543374_2	926569.ANT_06370	5.604e-110	367.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH2_k127_3543374_9	617140.AJZE01000062_gene2964	2.828e-45	173.0	COG2746@1|root,COG2746@2|Bacteria,1MZ5F@1224|Proteobacteria,1TK0N@1236|Gammaproteobacteria,1Y1XG@135623|Vibrionales	135623|Vibrionales	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
WLSH2_k127_3543374_3	436308.Nmar_0137	1.347e-97	334.0	COG2234@1|root,arCOG02959@2157|Archaea	2157|Archaea	S	Peptidase M28	ywaD2	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WLSH2_k127_3543374_10	1521187.JPIM01000048_gene85	1.963e-26	112.0	COG1861@1|root,COG1861@2|Bacteria,2G8I7@200795|Chloroflexi	200795|Chloroflexi	M	Cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
WLSH2_k127_3573897_1	397287.C807_03488	2.783e-103	345.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,27UCH@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PEP-utilising enzyme, mobile domain	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_3573897_2	406124.ACPC01000043_gene1820	1.288e-92	318.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,Sugar_tr
WLSH2_k127_3573897_3	1229172.JQFA01000002_gene2146	1.938e-68	252.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_3573897_4	1120949.KB903329_gene9218	6.026e-14	75.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3573897_0	42256.RradSPS_0358	1.051e-181	604.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_3573897_6	1227457.C451_00955	7.383e-09	63.0	arCOG09146@1|root,arCOG09146@2157|Archaea,2XVE2@28890|Euryarchaeota,23UK9@183963|Halobacteria	183963|Halobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3573897_5	472759.Nhal_0786	2.062e-13	78.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
WLSH2_k127_3573897_7	338966.Ppro_1938	0.000778	46.0	COG1964@1|root,COG1964@2|Bacteria,1QE02@1224|Proteobacteria,42M4B@68525|delta/epsilon subdivisions,2WJDI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
WLSH2_k127_3578525_7	646529.Desaci_2079	8.042e-31	141.0	COG4409@1|root,COG4409@2|Bacteria,1UMID@1239|Firmicutes,24CGE@186801|Clostridia	186801|Clostridia	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3578525_11	459495.SPLC1_S532970	8.311e-09	69.0	COG0515@1|root,COG0515@2|Bacteria,1G0B6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	spkD	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4101,Pkinase,SH3_3
WLSH2_k127_3578525_0	526227.Mesil_0601	8.19e-199	631.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
WLSH2_k127_3578525_1	439235.Dalk_4295	1.67e-190	607.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,42NVR@68525|delta/epsilon subdivisions,2WM9A@28221|Deltaproteobacteria,2MMWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
WLSH2_k127_3578525_8	466088.CL42_13010	9.143e-30	123.0	2DP1M@1|root,3305U@2|Bacteria,1P038@1224|Proteobacteria,1SRZA@1236|Gammaproteobacteria,3NS4S@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3578525_2	1499967.BAYZ01000018_gene6344	8.769e-150	480.0	COG3191@1|root,COG3191@2|Bacteria,2NNR0@2323|unclassified Bacteria	2|Bacteria	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WLSH2_k127_3578525_9	1463936.JOJI01000016_gene224	7.26e-20	96.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WLSH2_k127_3578525_3	926569.ANT_14140	5.37e-88	298.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WLSH2_k127_3578525_4	1123489.AUAN01000002_gene926	4.093e-49	188.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4H32Z@909932|Negativicutes	909932|Negativicutes	P	oligopeptide transport system permease protein OppB	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
WLSH2_k127_3578525_5	1128421.JAGA01000002_gene832	1.985e-47	182.0	COG1173@1|root,COG1173@2|Bacteria,2NQ14@2323|unclassified Bacteria	2|Bacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
WLSH2_k127_3578525_6	670487.Ocepr_0734	8.808e-35	141.0	COG0560@1|root,COG0560@2|Bacteria,1WKQA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
WLSH2_k127_3607832_0	10228.TriadP62141	3.342e-144	469.0	COG0405@1|root,KOG2410@2759|Eukaryota,38ENY@33154|Opisthokonta,3BN8F@33208|Metazoa	33208|Metazoa	E	Gamma-glutamyltranspeptidase 2-like	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WLSH2_k127_3607832_1	926569.ANT_06740	6.715e-129	424.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1
WLSH2_k127_3607832_2	118163.Ple7327_1873	1.432e-30	141.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VM99@52604|Pleurocapsales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_9,PHY
WLSH2_k127_3638723_13	926569.ANT_30300	4.072e-59	207.0	2FH2K@1|root,348XD@2|Bacteria,2G93E@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3638723_12	509191.AEDB02000081_gene2454	5.629e-61	219.0	COG4894@1|root,COG4894@2|Bacteria,1VUCV@1239|Firmicutes,250FU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3638723_10	926569.ANT_30130	1.39e-65	239.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
WLSH2_k127_3638723_4	926569.ANT_30130	1.305e-99	337.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
WLSH2_k127_3638723_9	926569.ANT_30120	6.711e-71	249.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WLSH2_k127_3638723_20	926550.CLDAP_10230	1.018e-23	113.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	3.5.1.104	ko:K21449,ko:K22278	-	-	-	-	ko00000,ko01000,ko02000	1.B.40.2	-	-	LysM,PG_binding_1,PG_binding_4,YkuD
WLSH2_k127_3638723_8	926569.ANT_30110	1.919e-72	252.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
WLSH2_k127_3638723_15	926569.ANT_04460	7.967e-43	162.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi	200795|Chloroflexi	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WLSH2_k127_3638723_11	926569.ANT_04450	6.466e-65	228.0	COG2078@1|root,COG2078@2|Bacteria	2|Bacteria	S	ferrous iron binding	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
WLSH2_k127_3638723_6	926569.ANT_03580	6.709e-87	310.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03580|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3638723_3	28072.Nos7524_5078	7.344e-115	393.0	COG1807@1|root,COG1807@2|Bacteria,1G0W2@1117|Cyanobacteria,1HRA1@1161|Nostocales	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH2_k127_3638723_16	926569.ANT_15180	7.174e-42	158.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
WLSH2_k127_3638723_0	316274.Haur_0812	3.654e-213	667.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi,376I0@32061|Chloroflexia	32061|Chloroflexia	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
WLSH2_k127_3638723_17	926569.ANT_15190	1.49e-34	137.0	2DTJR@1|root,33KPB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3638723_18	32057.KB217478_gene431	4.468e-33	143.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria,1HM0P@1161|Nostocales	1117|Cyanobacteria	I	TIGRFAM lipid kinase, YegS Rv2252 BmrU family	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WLSH2_k127_3638723_5	926569.ANT_15210	2.631e-99	343.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_3638723_7	1121396.KB893068_gene1448	1.669e-72	250.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2MHRY@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WLSH2_k127_3638723_14	1499967.BAYZ01000110_gene3008	2.191e-55	209.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,rve,rve_3
WLSH2_k127_3638723_22	926569.ANT_15230	5.847e-22	97.0	COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi	200795|Chloroflexi	J	ribosomal protein L28	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WLSH2_k127_3638723_21	1232430.CAVG010000121_gene1165	1.305e-22	101.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,4HIS4@91061|Bacilli,4GZ54@90964|Staphylococcaceae	91061|Bacilli	S	Asp23 family, cell envelope-related function	yloU	-	-	-	-	-	-	-	-	-	-	-	Asp23
WLSH2_k127_3638723_1	926569.ANT_15250	5.303e-209	663.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
WLSH2_k127_3638723_2	926569.ANT_19910	8.57e-116	381.0	COG3407@1|root,COG3407@2|Bacteria,2G5SQ@200795|Chloroflexi	200795|Chloroflexi	I	GHMP kinases N terminal domain	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
WLSH2_k127_3638723_19	745718.JADT01000019_gene1521	3.684e-28	120.0	COG0500@1|root,COG0500@2|Bacteria,4PMC2@976|Bacteroidetes	976|Bacteroidetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
WLSH2_k127_3698639_1	1273538.G159_04940	1.047e-17	88.0	2DNVA@1|root,32ZBE@2|Bacteria,1W480@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3698639_0	42256.RradSPS_0358	4.363e-252	805.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_372637_5	134676.ACPL_7882	4.903e-24	106.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria,4DBGR@85008|Micromonosporales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_372637_1	266779.Meso_3021	7.174e-130	426.0	COG2309@1|root,COG2309@2|Bacteria,1MW2Y@1224|Proteobacteria,2TSGB@28211|Alphaproteobacteria,43I54@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Leucyl aminopeptidase (Aminopeptidase T)	ampS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WLSH2_k127_372637_3	326423.RBAM_014190	2.279e-119	397.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,1ZCU3@1386|Bacillus	91061|Bacilli	E	COG2309 Leucyl aminopeptidase (aminopeptidase T)	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WLSH2_k127_372637_0	1521187.JPIM01000001_gene834	9.901e-179	566.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_372637_6	1288826.MSNKSG1_17266	1.014e-09	66.0	2EI3W@1|root,33BVA@2|Bacteria,1NPW4@1224|Proteobacteria,1SGBC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_372637_4	926569.ANT_15670	6.095e-85	309.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_372637_2	383372.Rcas_2077	6.086e-128	422.0	COG0366@1|root,COG0366@2|Bacteria,2G7SV@200795|Chloroflexi	200795|Chloroflexi	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
WLSH2_k127_3787032_1	215803.DB30_8826	1.04e-63	220.0	28H95@1|root,2Z7KY@2|Bacteria,1RA0C@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
WLSH2_k127_3787032_3	871968.DESME_06580	4.63e-08	66.0	COG2234@1|root,COG2234@2|Bacteria,1VBQF@1239|Firmicutes,25B63@186801|Clostridia,264IR@186807|Peptococcaceae	186801|Clostridia	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WLSH2_k127_3787032_4	313612.L8106_14845	0.0003371	47.0	COG3293@1|root,COG3293@2|Bacteria,1FZVT@1117|Cyanobacteria,1HHIP@1150|Oscillatoriales	1117|Cyanobacteria	L	COG3293 Transposase and inactivated derivatives	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
WLSH2_k127_3787032_0	329726.AM1_6258	4.564e-115	384.0	COG3464@1|root,COG3464@2|Bacteria,1G42D@1117|Cyanobacteria	1117|Cyanobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_3787032_2	329726.AM1_1358	2.242e-33	132.0	COG3293@1|root,COG3293@2|Bacteria,1G0BW@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
WLSH2_k127_3808240_0	926569.ANT_06410	2.94e-178	571.0	COG1887@1|root,COG1887@2|Bacteria	2|Bacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
WLSH2_k127_3808240_1	926569.ANT_06400	4.387e-127	415.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
WLSH2_k127_3808240_2	926569.ANT_06390	5.263e-99	332.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
WLSH2_k127_3808240_3	926569.ANT_06380	3.63e-70	247.0	COG1861@1|root,COG1861@2|Bacteria,2G8I7@200795|Chloroflexi	200795|Chloroflexi	M	Cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
WLSH2_k127_3845015_1	240015.ACP_3313	2.661e-136	437.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JMQ0@204432|Acidobacteriia	204432|Acidobacteriia	F	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WLSH2_k127_3845015_4	1123376.AUIU01000012_gene1404	2.952e-68	246.0	COG1902@1|root,COG1902@2|Bacteria,3J14N@40117|Nitrospirae	40117|Nitrospirae	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
WLSH2_k127_3845015_8	706587.Desti_5083	3.811e-07	61.0	COG1575@1|root,COG1575@2|Bacteria,1PWVZ@1224|Proteobacteria,4349B@68525|delta/epsilon subdivisions,2X2PW@28221|Deltaproteobacteria,2MRJX@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WLSH2_k127_3845015_5	754436.JCM19237_2168	9.418e-30	131.0	COG0739@1|root,COG0739@2|Bacteria,1QJWI@1224|Proteobacteria,1THY9@1236|Gammaproteobacteria,1XXW6@135623|Vibrionales	135623|Vibrionales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH2_k127_3845015_7	208596.CAR_c10310	9.774e-08	59.0	2DS5A@1|root,33EKG@2|Bacteria,1VPZG@1239|Firmicutes,4HSKB@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3845015_3	644968.DFW101_2543	9.02e-69	255.0	COG3503@1|root,COG3503@2|Bacteria,1QQ9D@1224|Proteobacteria,431ME@68525|delta/epsilon subdivisions,2WWTB@28221|Deltaproteobacteria,2MC5V@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
WLSH2_k127_3845015_2	1242864.D187_000281	5.339e-94	321.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,42WQU@68525|delta/epsilon subdivisions,2WTEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
WLSH2_k127_3845015_0	290402.Cbei_3862	2.763e-144	474.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,36HNH@31979|Clostridiaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_3845015_6	768706.Desor_4320	4.296e-16	83.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,2642N@186807|Peptococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP pyruvate binding	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_3856077_7	926569.ANT_13820	5.391e-76	259.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WLSH2_k127_3856077_3	273068.TTE0898	2.255e-104	348.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,42EXB@68295|Thermoanaerobacterales	186801|Clostridia	D	TIGRFAM Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WLSH2_k127_3856077_12	926569.ANT_13800	1.375e-54	195.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
WLSH2_k127_3856077_1	926569.ANT_13790	7.734e-250	776.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WLSH2_k127_3856077_4	926569.ANT_13780	2.109e-101	338.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WLSH2_k127_3856077_0	926569.ANT_13770	7.63e-268	833.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WLSH2_k127_3856077_2	926569.ANT_06070	3.298e-143	463.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WLSH2_k127_3856077_6	1128421.JAGA01000003_gene3537	4.315e-87	293.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_3856077_5	1128421.JAGA01000003_gene3536	3.848e-99	342.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_3856077_24	1132855.KB913035_gene1521	0.0007132	48.0	COG4244@1|root,COG4244@2|Bacteria,1PJNX@1224|Proteobacteria,2W82R@28216|Betaproteobacteria,2KNIG@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
WLSH2_k127_3856077_19	926550.CLDAP_25310	1.123e-16	87.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	1.1.5.2	ko:K00117,ko:K21430	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	iSbBS512_1146.SbBS512_E2507	GSDH
WLSH2_k127_3856077_17	401526.TcarDRAFT_0950	1.133e-24	110.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4H2F4@909932|Negativicutes	909932|Negativicutes	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_like
WLSH2_k127_3856077_20	525904.Tter_0530	2.765e-14	75.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WLSH2_k127_3856077_15	28444.JODQ01000002_gene4623	5.366e-30	135.0	COG0823@1|root,COG2982@1|root,COG0823@2|Bacteria,COG2982@2|Bacteria,2H3MT@201174|Actinobacteria	201174|Actinobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
WLSH2_k127_3856077_18	1116472.MGMO_8c00230	4.936e-23	113.0	COG3391@1|root,COG5563@1|root,COG3391@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466,VPEP
WLSH2_k127_3856077_8	768710.DesyoDRAFT_1784	8.85e-63	222.0	COG2197@1|root,COG2197@2|Bacteria,1V407@1239|Firmicutes,24IMS@186801|Clostridia,265NV@186807|Peptococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WLSH2_k127_3856077_11	1123288.SOV_2c03000	1.102e-57	215.0	COG2202@1|root,COG3850@1|root,COG2202@2|Bacteria,COG3850@2|Bacteria,1UNYH@1239|Firmicutes,4H8IN@909932|Negativicutes	2|Bacteria	T	N-terminal 7TM region of histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,HisKA_7TM,MFS_1,PAS,PAS_3,PAS_9,PilJ
WLSH2_k127_3856077_21	413816.BBJP01000081_gene2897	2.932e-10	71.0	COG0642@1|root,arCOG02327@2157|Archaea,2XT8K@28890|Euryarchaeota,23U1Y@183963|Halobacteria	183963|Halobacteria	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_7TM,PAS_4,PAS_8
WLSH2_k127_3856077_16	330214.NIDE0193	1.353e-25	119.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
WLSH2_k127_3856077_9	1120998.AUFC01000012_gene472	2.441e-61	219.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24C8S@186801|Clostridia	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K11624	ko02020,map02020	M00484	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WLSH2_k127_3856077_10	1123288.SOV_2c03000	1.156e-58	225.0	COG2202@1|root,COG3850@1|root,COG2202@2|Bacteria,COG3850@2|Bacteria,1UNYH@1239|Firmicutes,4H8IN@909932|Negativicutes	2|Bacteria	T	N-terminal 7TM region of histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,HisKA_7TM,MFS_1,PAS,PAS_3,PAS_9,PilJ
WLSH2_k127_3856077_13	1306406.ASHX01000001_gene4469	1.952e-43	179.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF11,PKD,PPC
WLSH2_k127_3856077_14	1519464.HY22_00625	7.474e-31	140.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	Beta_helix,DUF11,HemolysinCabind,PT-VENN
WLSH2_k127_3864431_11	926569.ANT_05890	3.344e-51	189.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
WLSH2_k127_3864431_1	926569.ANT_05900	4.415e-185	586.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_3864431_10	926569.ANT_05910	2.19e-52	194.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
WLSH2_k127_3864431_9	1297569.MESS2_450014	3.725e-59	216.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,43HRV@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
WLSH2_k127_3864431_3	1089553.Tph_c26530	2.118e-168	544.0	COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
WLSH2_k127_3864431_5	754027.HMPREF9554_01554	6.009e-140	452.0	COG0180@1|root,COG0180@2|Bacteria,2J68U@203691|Spirochaetes	203691|Spirochaetes	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WLSH2_k127_3864431_4	926569.ANT_05950	7.133e-156	507.0	COG0147@1|root,COG1169@1|root,COG0147@2|Bacteria,COG1169@2|Bacteria,2G5M7@200795|Chloroflexi	200795|Chloroflexi	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
WLSH2_k127_3864431_6	1242864.D187_003310	1.515e-130	424.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WLSH2_k127_3864431_2	290397.Adeh_2070	8.298e-174	550.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WLSH2_k127_3864431_0	290397.Adeh_2071	3.883e-249	777.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
WLSH2_k127_3864431_7	926569.ANT_03320	1.008e-74	255.0	COG0066@1|root,COG0066@2|Bacteria,2G6JE@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
WLSH2_k127_3864431_8	313612.L8106_13140	8.674e-68	238.0	COG0500@1|root,COG2226@2|Bacteria,1G1SP@1117|Cyanobacteria,1H91U@1150|Oscillatoriales	1117|Cyanobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_3899701_9	926569.ANT_11710	1.265e-93	313.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH2_k127_3899701_15	867845.KI911784_gene997	5.226e-74	254.0	COG0517@1|root,COG0517@2|Bacteria,2G6TI@200795|Chloroflexi,376YQ@32061|Chloroflexia	32061|Chloroflexia	S	amino acid-binding ACT domain protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
WLSH2_k127_3899701_1	880072.Desac_1601	1.33e-262	827.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
WLSH2_k127_3899701_3	926569.ANT_19690	3.86e-213	671.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_3899701_10	1278307.KB907016_gene3433	9.003e-90	303.0	COG2267@1|root,COG2267@2|Bacteria,1R299@1224|Proteobacteria,1T5JY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_3899701_7	926569.ANT_22320	5.515e-105	353.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WLSH2_k127_3899701_23	926569.ANT_22310	5.102e-35	138.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi	200795|Chloroflexi	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WLSH2_k127_3899701_14	926569.ANT_22300	2.689e-74	268.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
WLSH2_k127_3899701_4	1444309.JAQG01000164_gene1837	4.454e-137	454.0	COG2304@1|root,COG2304@2|Bacteria,1TSU7@1239|Firmicutes,4HPXN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
WLSH2_k127_3899701_37	1229172.JQFA01000004_gene1781	1.351e-06	52.0	COG5433@1|root,COG5433@2|Bacteria,1G7IY@1117|Cyanobacteria,1HHE3@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_3899701_0	926569.ANT_16840	0.0	1137.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WLSH2_k127_3899701_25	163908.KB235896_gene2282	2.722e-30	120.0	COG2442@1|root,COG2442@2|Bacteria,1G869@1117|Cyanobacteria,1HSSK@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WLSH2_k127_3899701_39	179408.Osc7112_0570	5.769e-06	48.0	COG4634@1|root,COG4634@2|Bacteria,1G8GS@1117|Cyanobacteria,1HCSC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3899701_27	179408.Osc7112_0570	3.088e-21	94.0	COG4634@1|root,COG4634@2|Bacteria,1G8GS@1117|Cyanobacteria,1HCSC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3899701_13	521045.Kole_0611	2.381e-78	269.0	COG1272@1|root,COG1272@2|Bacteria,2GCUZ@200918|Thermotogae	200918|Thermotogae	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
WLSH2_k127_3899701_34	264732.Moth_1271	3.728e-10	74.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,24S59@186801|Clostridia,42J2N@68295|Thermoanaerobacterales	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WLSH2_k127_3899701_16	696747.NIES39_C05180	4.202e-72	272.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
WLSH2_k127_3899701_17	234267.Acid_0172	6.991e-68	239.0	29WUK@1|root,30IG1@2|Bacteria,3Y5ZU@57723|Acidobacteria	57723|Acidobacteria	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
WLSH2_k127_3899701_28	1047013.AQSP01000111_gene1661	3.346e-19	90.0	COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria	2|Bacteria	O	peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
WLSH2_k127_3899701_29	1303518.CCALI_01835	4.695e-18	94.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-1	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_3899701_31	631362.Thi970DRAFT_03746	3.556e-14	76.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria	1224|Proteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
WLSH2_k127_3899701_19	1121272.KB903250_gene2710	2.932e-53	199.0	COG0671@1|root,COG0671@2|Bacteria,2IPT0@201174|Actinobacteria	201174|Actinobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WLSH2_k127_3899701_24	1122134.KB893650_gene1737	2.354e-33	131.0	2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,1S8M3@1236|Gammaproteobacteria,1XPJY@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WLSH2_k127_3899701_36	926562.Oweho_0806	8.282e-09	57.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,1I4BI@117743|Flavobacteriia,2PBSI@246874|Cryomorphaceae	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WLSH2_k127_3899701_5	926550.CLDAP_08640	1.825e-121	400.0	COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,FecR,LysM,Peptidase_S9
WLSH2_k127_3899701_12	1403819.BATR01000053_gene1643	2.034e-85	289.0	COG0406@1|root,COG0406@2|Bacteria,46T4J@74201|Verrucomicrobia,2IV5M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WLSH2_k127_3899701_38	5911.EAR82375	4.747e-06	59.0	2CYSW@1|root,2S679@2759|Eukaryota,3ZE4R@5878|Ciliophora	5878|Ciliophora	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WLSH2_k127_3899701_30	926569.ANT_31290	2.636e-15	89.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
WLSH2_k127_3899701_11	272134.KB731324_gene5924	4.443e-86	319.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,PD40,SpoIIE,TIR_2,WD40
WLSH2_k127_3899701_20	1173027.Mic7113_1369	2.308e-52	203.0	COG0457@1|root,COG0457@2|Bacteria,1G8AT@1117|Cyanobacteria,1HCX3@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
WLSH2_k127_3899701_2	1173027.Mic7113_1369	6.891e-214	689.0	COG0457@1|root,COG0457@2|Bacteria,1G8AT@1117|Cyanobacteria,1HCX3@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
WLSH2_k127_3899701_22	316274.Haur_0342	8.92e-38	149.0	COG1428@1|root,COG1428@2|Bacteria,2G8Z7@200795|Chloroflexi	200795|Chloroflexi	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
WLSH2_k127_3899701_18	1313301.AUGC01000014_gene2498	2.182e-57	206.0	COG0346@1|root,COG0346@2|Bacteria,4NREW@976|Bacteroidetes	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WLSH2_k127_3899701_8	646529.Desaci_2502	3.694e-102	338.0	COG0412@1|root,COG0412@2|Bacteria,1UZRU@1239|Firmicutes	1239|Firmicutes	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
WLSH2_k127_3899701_26	345341.KUTG_01351	1.528e-22	99.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria,4E7K2@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3899701_6	1250005.PHEL85_0834	1.069e-105	348.0	COG1864@1|root,COG1864@2|Bacteria,4NMN6@976|Bacteroidetes,1I8WS@117743|Flavobacteriia	976|Bacteroidetes	L	DNA/RNA non-specific endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS
WLSH2_k127_3899701_32	1519464.HY22_14065	1.335e-13	80.0	2DDRS@1|root,2ZJ0Y@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
WLSH2_k127_3899701_21	404589.Anae109_3135	6.99e-38	145.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WLSH2_k127_3946208_0	35754.JNYJ01000019_gene80	1.367e-122	424.0	COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales	201174|Actinobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12
WLSH2_k127_3946208_1	1449126.JQKL01000047_gene2728	1.435e-19	88.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,268PP@186813|unclassified Clostridiales	186801|Clostridia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
WLSH2_k127_4004196_6	1117647.M5M_00895	1.315e-12	69.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,1RNSW@1236|Gammaproteobacteria,1J4SC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WLSH2_k127_4004196_5	386456.JQKN01000021_gene35	6.619e-14	72.0	arCOG09714@1|root,arCOG09714@2157|Archaea,2Y0H8@28890|Euryarchaeota,23P85@183925|Methanobacteria	183925|Methanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4004196_7	352165.HMPREF7215_0586	6.902e-09	59.0	arCOG09714@1|root,316P9@2|Bacteria,3TCH4@508458|Synergistetes	508458|Synergistetes	S	COG NOG16854 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4004196_2	1033810.HLPCO_001074	1.546e-35	148.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,Methyltransf_25
WLSH2_k127_4004196_8	536227.CcarbDRAFT_4028	1.404e-07	63.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	sagE	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_4004196_4	410358.Mlab_1184	6.494e-31	134.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,2NAUF@224756|Methanomicrobia	224756|Methanomicrobia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_4004196_1	58344.JOEL01000016_gene5882	2.894e-59	225.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	3.5.2.18	ko:K15358	ko00760,ko01120,map00760,map01120	-	R07984	RC01933	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WLSH2_k127_4004196_0	29306.JOBE01000012_gene6482	1.424e-143	475.0	COG1680@1|root,COG4412@1|root,COG1680@2|Bacteria,COG4412@2|Bacteria,2I8QH@201174|Actinobacteria	201174|Actinobacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Peptidase_M6
WLSH2_k127_4032599_1	926569.ANT_15080	2.831e-23	106.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_4032599_2	926569.ANT_15080	2.055e-22	108.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_4032599_0	926569.ANT_22190	4.103e-86	301.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_4032599_4	926569.ANT_22190	1.982e-19	98.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_4032599_3	926569.ANT_22190	3.235e-21	101.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_4032599_5	765420.OSCT_0053	7.808e-09	61.0	COG0582@1|root,COG0582@2|Bacteria,2G8NN@200795|Chloroflexi,377FN@32061|Chloroflexia	32061|Chloroflexia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
WLSH2_k127_4065057_3	357808.RoseRS_0445	3.347e-25	113.0	2DMC8@1|root,32J63@2|Bacteria	357808.RoseRS_0445|-	L	each copy contains a frameshift at the sequence CCCCCCTTTTT and 7 copies of repeat with repeat unit SCEEP	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4065057_2	357808.RoseRS_3382	2.841e-44	169.0	2DMC8@1|root,32J63@2|Bacteria	357808.RoseRS_3382|-	L	each copy contains a frameshift at the sequence CCCCCCTTTTT and 7 copies of repeat with repeat unit SCEEP	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4065057_1	608506.COB47_0803	2.668e-56	204.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,42FEQ@68295|Thermoanaerobacterales	186801|Clostridia	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WLSH2_k127_4065057_0	742765.HMPREF9457_03673	1.12e-210	679.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,27V45@189330|Dorea	186801|Clostridia	K	Likely ribonuclease with RNase H fold.	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
WLSH2_k127_4065057_7	633697.EubceDRAFT1_2240	0.0003245	49.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,25VNQ@186806|Eubacteriaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
WLSH2_k127_4065057_5	1321778.HMPREF1982_02247	7.267e-09	59.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,267T0@186813|unclassified Clostridiales	186801|Clostridia	KL	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
WLSH2_k127_4065057_6	1043493.BBLU01000003_gene2450	1.046e-06	53.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria	201174|Actinobacteria	K	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
WLSH2_k127_4065057_4	102232.GLO73106DRAFT_00015700	1.039e-09	59.0	COG4113@1|root,COG4113@2|Bacteria,1G8IF@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_4066044_0	1049564.TevJSym_bb00130	1.731e-146	477.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1J4BX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	penicillin-binding protein	mrcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
WLSH2_k127_4066044_1	1279019.ARQK01000031_gene1211	1.16e-27	116.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
WLSH2_k127_4114916_17	1459636.NTE_00544	0.0003961	46.0	COG1522@1|root,arCOG01580@2157|Archaea	2157|Archaea	K	COG1522 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_11,HTH_24
WLSH2_k127_4114916_0	926569.ANT_12980	2.263e-306	979.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
WLSH2_k127_4114916_4	316274.Haur_4305	8.357e-97	329.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,374VF@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
WLSH2_k127_4114916_10	926569.ANT_16620	8.934e-68	239.0	COG0647@1|root,COG0647@2|Bacteria,2G6G5@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
WLSH2_k127_4114916_7	309801.trd_A0702	1.219e-87	297.0	COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi,27Y6W@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
WLSH2_k127_4114916_8	926569.ANT_16610	4.403e-86	291.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WLSH2_k127_4114916_9	926569.ANT_16600	1.301e-79	284.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WLSH2_k127_4114916_13	926569.ANT_16590	8.997e-35	138.0	29ATW@1|root,2ZXTA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4114916_16	293826.Amet_1623	5.975e-05	54.0	COG1266@1|root,COG1266@2|Bacteria,1V1B4@1239|Firmicutes,25CEY@186801|Clostridia,36WUT@31979|Clostridiaceae	186801|Clostridia	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_4114916_15	706587.Desti_3197	5.758e-09	66.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WLSH2_k127_4114916_6	304371.MCP_1301	8.191e-90	316.0	arCOG09180@1|root,arCOG09180@2157|Archaea,2XTAJ@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
WLSH2_k127_4114916_1	304371.MCP_1300	1.438e-132	428.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_4114916_5	304371.MCP_1301	3.391e-94	329.0	arCOG09180@1|root,arCOG09180@2157|Archaea,2XTAJ@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
WLSH2_k127_4114916_2	304371.MCP_1300	3.316e-129	418.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_4114916_12	645991.Sgly_0951	1.651e-50	185.0	COG1051@1|root,COG1051@2|Bacteria,1V466@1239|Firmicutes,24PBY@186801|Clostridia,262DY@186807|Peptococcaceae	186801|Clostridia	F	PFAM NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
WLSH2_k127_4114916_14	493475.GARC_0477	1.637e-27	122.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria,1SAFU@1236|Gammaproteobacteria,468T4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
WLSH2_k127_4114916_3	118161.KB235922_gene3697	1.122e-103	351.0	COG1680@1|root,COG1680@2|Bacteria,1G45A@1117|Cyanobacteria	1117|Cyanobacteria	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WLSH2_k127_4114916_11	744980.TRICHSKD4_5107	1.398e-50	182.0	COG0662@1|root,COG0662@2|Bacteria,1N56T@1224|Proteobacteria,2UCUS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_4136556_14	671143.DAMO_0652	3.1e-82	278.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_4136556_5	671143.DAMO_0652	7.417e-130	421.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_4136556_1	926550.CLDAP_38240	4.823e-262	815.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH2_k127_4136556_19	378806.STAUR_7979	1.817e-41	158.0	2E2RY@1|root,32XUA@2|Bacteria,1N9C1@1224|Proteobacteria,42XP0@68525|delta/epsilon subdivisions,2WT7T@28221|Deltaproteobacteria,2YVJE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
WLSH2_k127_4136556_11	378806.STAUR_7837	1.413e-103	347.0	COG0451@1|root,COG0451@2|Bacteria,1RBSM@1224|Proteobacteria,42XUG@68525|delta/epsilon subdivisions,2WTSY@28221|Deltaproteobacteria,2YX8Q@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
WLSH2_k127_4136556_3	1437882.AZRU01000042_gene4585	2.129e-149	487.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,1RM95@1236|Gammaproteobacteria,1YE9N@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Biotin carboxylase, N-terminal domain	mccA	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
WLSH2_k127_4136556_24	926550.CLDAP_16280	5.197e-19	94.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
WLSH2_k127_4136556_15	204669.Acid345_4730	1.28e-64	231.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,3Y2H3@57723|Acidobacteria,2JHTN@204432|Acidobacteriia	2|Bacteria	T	cyclic nucleotide-binding	yejC	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	DUF1003
WLSH2_k127_4136556_16	926550.CLDAP_16300	3.955e-61	213.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
WLSH2_k127_4136556_13	8083.ENSXMAP00000011022	3.002e-83	287.0	COG2301@1|root,2QQPK@2759|Eukaryota,38GJH@33154|Opisthokonta,3BAH3@33208|Metazoa,3CUC8@33213|Bilateria,482FQ@7711|Chordata,48Z08@7742|Vertebrata,49RTX@7898|Actinopterygii	33208|Metazoa	F	Citrate lyase	CLYBL	GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401	-	ko:K11390	-	-	-	-	ko00000,ko01000	-	-	-	HpcH_HpaI
WLSH2_k127_4136556_30	1521187.JPIM01000156_gene1082	5.017e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,2GA74@200795|Chloroflexi,375MU@32061|Chloroflexia	32061|Chloroflexia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4136556_18	1265505.ATUG01000001_gene4242	1.495e-53	199.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria,2MNCD@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_4136556_17	1265505.ATUG01000001_gene4242	8.338e-55	202.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria,2MNCD@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_4136556_12	1480694.DC28_04735	7.762e-91	311.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4136556_6	2423.NA23_0209425	2.001e-128	416.0	COG0863@1|root,COG0863@2|Bacteria,2GD2C@200918|Thermotogae	200918|Thermotogae	H	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WLSH2_k127_4136556_20	1379698.RBG1_1C00001G0504	5.023e-33	132.0	COG0629@1|root,COG0629@2|Bacteria,2NPP5@2323|unclassified Bacteria	2|Bacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH2_k127_4136556_26	926550.CLDAP_34200	8.457e-14	73.0	2E5PY@1|root,330EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4136556_10	383372.Rcas_0333	2.515e-106	352.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,374TX@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
WLSH2_k127_4136556_4	1242864.D187_000739	7.501e-131	424.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,42QSZ@68525|delta/epsilon subdivisions,2WN50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
WLSH2_k127_4136556_23	357808.RoseRS_0605	4.153e-22	110.0	COG0823@1|root,COG0823@2|Bacteria,2GB83@200795|Chloroflexi,377J2@32061|Chloroflexia	32061|Chloroflexia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4136556_25	1382356.JQMP01000004_gene40	1.059e-15	79.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YH0@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
WLSH2_k127_4136556_21	926569.ANT_04420	3.016e-30	124.0	COG3870@1|root,COG3870@2|Bacteria	2|Bacteria	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
WLSH2_k127_4136556_8	765910.MARPU_00280	1.499e-110	372.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1WZAK@135613|Chromatiales	135613|Chromatiales	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
WLSH2_k127_4136556_28	500633.CLOHIR_02218	3.283e-09	65.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,25TEH@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_4136556_9	357808.RoseRS_1116	3.98e-107	358.0	COG0530@1|root,COG0530@2|Bacteria,2G6GV@200795|Chloroflexi,376V8@32061|Chloroflexia	32061|Chloroflexia	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WLSH2_k127_4136556_2	926569.ANT_01050	8.669e-179	565.0	COG0240@1|root,COG0240@2|Bacteria,2G6HJ@200795|Chloroflexi	200795|Chloroflexi	C	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain	-	-	1.5.1.28	ko:K04940	-	-	-	-	ko00000,ko01000	-	-	-	NAD_Gly3P_dh_N,Octopine_DH
WLSH2_k127_4136556_0	357808.RoseRS_2459	1.995e-268	834.0	COG5012@1|root,COG5012@2|Bacteria,2G66F@200795|Chloroflexi,376VS@32061|Chloroflexia	32061|Chloroflexia	S	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
WLSH2_k127_4136556_7	1379698.RBG1_1C00001G1677	8.571e-125	409.0	COG3239@1|root,COG3239@2|Bacteria,2NNTZ@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
WLSH2_k127_4136556_27	1173027.Mic7113_2064	1.313e-09	60.0	2E849@1|root,332I1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_3
WLSH2_k127_4136556_29	1443125.Z962_03455	4.986e-07	53.0	2E849@1|root,332I1@2|Bacteria,1VXYE@1239|Firmicutes,24K1P@186801|Clostridia,36JY3@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_3
WLSH2_k127_4209243_25	926569.ANT_14520	1.099e-71	253.0	COG3608@1|root,COG3608@2|Bacteria,2G71G@200795|Chloroflexi	200795|Chloroflexi	S	succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	-
WLSH2_k127_4209243_38	1121957.ATVL01000007_gene2357	1.95e-32	136.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,47PCZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
WLSH2_k127_4209243_34	926550.CLDAP_05380	4.454e-42	160.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
WLSH2_k127_4209243_37	497964.CfE428DRAFT_3478	9.405e-40	156.0	COG4330@1|root,COG4330@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
WLSH2_k127_4209243_23	439235.Dalk_1565	9.067e-80	275.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42P9B@68525|delta/epsilon subdivisions,2WMCP@28221|Deltaproteobacteria,2MMBX@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
WLSH2_k127_4209243_2	926550.CLDAP_00970	2.31e-240	763.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_4209243_3	926569.ANT_14490	4.578e-185	589.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
WLSH2_k127_4209243_30	926569.ANT_20600	3.611e-45	169.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4209243_5	555779.Dthio_PD2814	8.438e-176	557.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2WM0Y@28221|Deltaproteobacteria,2M98D@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
WLSH2_k127_4209243_33	926569.ANT_11610	2.43e-44	166.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.53,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K13669,ko:K19710	ko00230,map00230	-	R00126,R01054,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT87	-	GT87,NUDIX
WLSH2_k127_4209243_39	926560.KE387023_gene3515	2.145e-31	134.0	2BN1I@1|root,32GMQ@2|Bacteria,1WN4C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4209243_35	485916.Dtox_1078	8.187e-42	169.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,260MY@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
WLSH2_k127_4209243_22	335543.Sfum_0906	2.293e-81	273.0	COG1839@1|root,COG1839@2|Bacteria,1RBCB@1224|Proteobacteria,42S44@68525|delta/epsilon subdivisions,2WMAS@28221|Deltaproteobacteria,2MQHJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
WLSH2_k127_4209243_28	926569.ANT_11620	7.125e-62	218.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi	200795|Chloroflexi	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
WLSH2_k127_4209243_10	926569.ANT_11630	1.926e-122	401.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WLSH2_k127_4209243_36	439235.Dalk_2449	1.836e-41	172.0	COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,42XJQ@68525|delta/epsilon subdivisions,2WSMN@28221|Deltaproteobacteria,2MP2F@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4209243_29	246197.MXAN_1633	2.328e-56	203.0	COG1670@1|root,COG1670@2|Bacteria,1RKT9@1224|Proteobacteria,42VCK@68525|delta/epsilon subdivisions,2WS7R@28221|Deltaproteobacteria,2Z14V@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	rimJ2	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WLSH2_k127_4209243_6	926569.ANT_11650	2.418e-152	491.0	COG1239@1|root,COG1239@2|Bacteria,2G832@200795|Chloroflexi	200795|Chloroflexi	H	SMART AAA ATPase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase
WLSH2_k127_4209243_32	479434.Sthe_0091	5.861e-45	168.0	COG1607@1|root,COG1607@2|Bacteria,2G7A6@200795|Chloroflexi	200795|Chloroflexi	I	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WLSH2_k127_4209243_0	926569.ANT_21050	2.399e-293	912.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
WLSH2_k127_4209243_46	998674.ATTE01000001_gene3159	1.4e-12	78.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria,4625I@72273|Thiotrichales	72273|Thiotrichales	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WLSH2_k127_4209243_12	926569.ANT_21060	5.625e-108	362.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
WLSH2_k127_4209243_13	1379698.RBG1_1C00001G1223	2.303e-107	361.0	COG0665@1|root,COG0665@2|Bacteria,2NP0X@2323|unclassified Bacteria	2|Bacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
WLSH2_k127_4209243_20	1499967.BAYZ01000065_gene6085	2.258e-89	306.0	COG2423@1|root,COG2423@2|Bacteria,2NPI5@2323|unclassified Bacteria	2|Bacteria	E	Ornithine cyclodeaminase/mu-crystallin family	rapL	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
WLSH2_k127_4209243_17	525904.Tter_0589	8.182e-93	310.0	COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria	2|Bacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WLSH2_k127_4209243_16	926550.CLDAP_29810	5.789e-99	329.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WLSH2_k127_4209243_9	1168059.KB899087_gene4096	4.537e-127	426.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,3EYBW@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH2_k127_4209243_8	1128421.JAGA01000002_gene1295	3.463e-131	427.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH2_k127_4209243_7	1128421.JAGA01000002_gene1294	3.212e-136	447.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH2_k127_4209243_43	489825.LYNGBM3L_07030	1.549e-21	101.0	COG2267@1|root,COG2267@2|Bacteria,1GCG9@1117|Cyanobacteria	1117|Cyanobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4209243_11	926569.ANT_16410	7.001e-116	391.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
WLSH2_k127_4209243_42	926569.ANT_16420	6.04e-24	105.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
WLSH2_k127_4209243_31	926569.ANT_16430	3.764e-45	167.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4209243_21	880073.Calab_1950	2.886e-83	287.0	COG0708@1|root,COG0708@2|Bacteria,2NP5K@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WLSH2_k127_4209243_1	926569.ANT_20890	1.346e-287	894.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WLSH2_k127_4209243_4	671143.DAMO_2604	1.118e-178	576.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_4209243_14	926569.ANT_20910	5.096e-105	350.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH2_k127_4209243_41	926569.ANT_20920	2.504e-24	111.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
WLSH2_k127_4209243_24	926569.ANT_20930	1.094e-79	287.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi	200795|Chloroflexi	M	glycosyl transferase group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WLSH2_k127_4209243_48	523850.TON_0228	1.624e-06	53.0	COG2104@1|root,arCOG00535@2157|Archaea,2Y4FN@28890|Euryarchaeota,244NX@183968|Thermococci	183968|Thermococci	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH2_k127_4209243_18	1111069.TCCBUS3UF1_17660	6.634e-91	310.0	COG0037@1|root,COG0037@2|Bacteria,1WIQC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	2.8.1.15	ko:K14058,ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
WLSH2_k127_4209243_47	760011.Spico_1390	3.842e-10	66.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
WLSH2_k127_4209243_26	485913.Krac_11884	1.366e-70	249.0	COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi	200795|Chloroflexi	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
WLSH2_k127_4209243_44	383372.Rcas_4165	8.29e-16	89.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4209243_27	357808.RoseRS_0444	1.772e-63	231.0	COG3385@1|root,COG3385@2|Bacteria,2G9A6@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_4209243_40	1303518.CCALI_00071	4.533e-30	126.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_4209243_15	926550.CLDAP_20690	9.044e-102	344.0	COG0577@1|root,COG0577@2|Bacteria,2G6RX@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
WLSH2_k127_4209243_19	926550.CLDAP_20700	9.062e-90	301.0	COG1136@1|root,COG1136@2|Bacteria,2G6K8@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_4209243_49	935837.JAEK01000059_gene4869	3.497e-06	51.0	COG3401@1|root,COG3420@1|root,COG5263@1|root,COG5520@1|root,COG3401@2|Bacteria,COG3420@2|Bacteria,COG5263@2|Bacteria,COG5520@2|Bacteria,1TQ4E@1239|Firmicutes	1239|Firmicutes	M	O-Glycosyl hydrolase family 30	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydr_30_2,Glyco_hydro_30C
WLSH2_k127_4235998_4	926569.ANT_01250	6.629e-123	396.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH2_k127_4235998_7	292459.STH1632	1.192e-47	176.0	COG0406@1|root,COG1051@1|root,COG0406@2|Bacteria,COG1051@2|Bacteria,1VGJ7@1239|Firmicutes,24SQU@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_4235998_2	196162.Noca_1631	5.618e-139	447.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4DV65@85009|Propionibacteriales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH2_k127_4235998_1	926569.ANT_01240	1.737e-177	563.0	COG0624@1|root,COG0624@2|Bacteria,2G8AH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_4235998_6	926569.ANT_01230	3.831e-73	253.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WLSH2_k127_4235998_9	593117.TGAM_2125	9.566e-18	87.0	COG1917@1|root,arCOG02994@2157|Archaea,2XZAN@28890|Euryarchaeota,2446X@183968|Thermococci	183968|Thermococci	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_4235998_0	926569.ANT_01210	2.386e-216	679.0	COG0402@1|root,COG0402@2|Bacteria,2G5X1@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WLSH2_k127_4235998_3	7668.SPU_024663-tr	7.051e-130	459.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BAXI@33208|Metazoa	33208|Metazoa	M	Ankyrin 1, erythrocytic	-	-	-	ko:K10380,ko:K15502,ko:K15503	ko04624,ko05205,map04624,map05205	-	-	-	ko00000,ko00001,ko01009,ko03400,ko04812	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
WLSH2_k127_4235998_5	706587.Desti_5093	2.271e-83	297.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_4235998_10	211165.AJLN01000097_gene5088	4.509e-15	77.0	COG0286@1|root,COG0286@2|Bacteria,1G36A@1117|Cyanobacteria	1117|Cyanobacteria	V	helicase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
WLSH2_k127_4235998_13	242159.ABO96031	0.0004643	48.0	2AHTF@1|root,2S2PD@2759|Eukaryota,389P4@33090|Viridiplantae,34MIJ@3041|Chlorophyta	3041|Chlorophyta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4235998_11	399795.CtesDRAFT_PD1070	1.043e-12	72.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VU57@28216|Betaproteobacteria,4AF5D@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH2_k127_4235998_12	1321784.HMPREF1987_01279	1.222e-12	76.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia	186801|Clostridia	K	PFAM Transcription factor CarD	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
WLSH2_k127_4235998_8	497964.CfE428DRAFT_6673	4.887e-26	110.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH2_k127_4239989_2	926554.KI912628_gene2716	3.259e-23	101.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
WLSH2_k127_4239989_0	485913.Krac_4421	1.415e-102	348.0	COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08162	-	-	-	-	ko00000,ko02000	2.A.1.2.21	-	-	MFS_1,MFS_1_like,Sugar_tr
WLSH2_k127_4239989_1	1308866.J416_03916	2.125e-37	141.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli,4707W@74385|Gracilibacillus	91061|Bacilli	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WLSH2_k127_4240358_4	251221.35214432	5.82e-11	64.0	COG2801@1|root,COG2801@2|Bacteria,1GDGY@1117|Cyanobacteria	1117|Cyanobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
WLSH2_k127_4240358_3	1118153.MOY_15988	9.675e-21	93.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria,1XI3W@135619|Oceanospirillales	135619|Oceanospirillales	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
WLSH2_k127_4240358_0	880072.Desac_2842	9.34e-122	400.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,42MUE@68525|delta/epsilon subdivisions,2WJFZ@28221|Deltaproteobacteria,2MR9K@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve
WLSH2_k127_4240358_2	1121116.KB894784_gene41	8.182e-29	120.0	COG2963@1|root,COG2963@2|Bacteria,1N1MP@1224|Proteobacteria,2VU5E@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
WLSH2_k127_4240358_1	449447.MAE_05120	2.968e-33	130.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1G3YK@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
WLSH2_k127_4328318_14	1122611.KB903988_gene7173	2.848e-07	56.0	2EFVT@1|root,339N0@2|Bacteria,2GWUH@201174|Actinobacteria,4EKY7@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4328318_9	926569.ANT_03100	4.324e-38	154.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4328318_6	926569.ANT_03090	1.997e-77	273.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WLSH2_k127_4328318_3	926569.ANT_03090	2.434e-109	363.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WLSH2_k127_4328318_12	1232410.KI421419_gene2510	1.184e-23	102.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg,SBP_bac_3
WLSH2_k127_4328318_7	1121456.ATVA01000019_gene1268	4.935e-62	220.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9,dCache_1
WLSH2_k127_4328318_13	32057.KB217478_gene1794	2.424e-14	83.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1HIN7@1161|Nostocales	1117|Cyanobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WLSH2_k127_4328318_5	706587.Desti_5093	9.674e-98	344.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_4328318_1	720554.Clocl_3061	9.166e-120	395.0	COG0451@1|root,COG0451@2|Bacteria,1TPYA@1239|Firmicutes,24A39@186801|Clostridia,3WHQG@541000|Ruminococcaceae	186801|Clostridia	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WLSH2_k127_4328318_4	525897.Dbac_0080	1.24e-99	334.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria,2M987@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
WLSH2_k127_4328318_10	926550.CLDAP_18620	5.734e-35	138.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
WLSH2_k127_4328318_11	926569.ANT_26820	4.647e-24	103.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
WLSH2_k127_4328318_2	926569.ANT_26810	4.027e-111	373.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria	2|Bacteria	K	Biogenesis protein	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K09792,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,Ferric_reduct,HMA
WLSH2_k127_4328318_8	926569.ANT_12580	1.831e-51	187.0	2EQH8@1|root,33I38@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4328318_0	926569.ANT_12590	0.0	1093.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH2_k127_4334200_8	1267535.KB906767_gene3015	8.832e-30	123.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3Y4F0@57723|Acidobacteria,2JKSY@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C
WLSH2_k127_4334200_4	469383.Cwoe_5927	3.909e-67	235.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,4CQ40@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
WLSH2_k127_4334200_9	401053.AciPR4_1215	1.665e-29	123.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
WLSH2_k127_4334200_7	269799.Gmet_3329	6.957e-46	170.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria,43VTP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
WLSH2_k127_4334200_1	443143.GM18_0459	1.874e-225	709.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hyaL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WLSH2_k127_4334200_10	357808.RoseRS_2320	6.594e-27	110.0	COG0374@1|root,COG0374@2|Bacteria,2G6SF@200795|Chloroflexi,376Y8@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WLSH2_k127_4334200_5	1304883.KI912532_gene1050	2.456e-58	218.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,2VNZ5@28216|Betaproteobacteria,2KVKW@206389|Rhodocyclales	206389|Rhodocyclales	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
WLSH2_k127_4334200_3	243231.GSU0783	6.101e-73	255.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42S59@68525|delta/epsilon subdivisions,2WNGW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hybA	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,TAT_signal
WLSH2_k127_4334200_2	1121918.ARWE01000001_gene3505	2.3e-115	382.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria,43TJR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	hyaS	-	1.12.2.1,1.12.99.6	ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3332	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
WLSH2_k127_4334200_11	1449126.JQKL01000002_gene1553	9.216e-23	104.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WLSH2_k127_4334200_0	1379698.RBG1_1C00001G0047	1.058e-226	710.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WLSH2_k127_4334200_6	429009.Adeg_2014	1.222e-53	194.0	COG1941@1|root,COG1941@2|Bacteria,1V21E@1239|Firmicutes,24GWD@186801|Clostridia,42HGR@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
WLSH2_k127_4395141_4	304371.MCP_0427	3.841e-21	97.0	arCOG07533@1|root,arCOG07533@2157|Archaea	304371.MCP_0427|-	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4395141_3	304371.MCP_0424	5.215e-42	162.0	arCOG07533@1|root,arCOG07533@2157|Archaea,2Y46E@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
WLSH2_k127_4395141_2	574375.BAGA_18610	5.027e-51	184.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
WLSH2_k127_4395141_1	574375.BAGA_18610	6.045e-72	246.0	COG0604@1|root,COG0604@2|Bacteria,1TSWF@1239|Firmicutes,4HANV@91061|Bacilli,1ZPZP@1386|Bacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
WLSH2_k127_4395141_0	485913.Krac_0278	1.122e-132	432.0	COG0604@1|root,COG0604@2|Bacteria,2G84Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WLSH2_k127_4395141_5	326427.Cagg_2198	1.524e-15	84.0	COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
WLSH2_k127_4396562_15	598467.BrE312_2495	9.909e-62	220.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974	DHO_dh
WLSH2_k127_4396562_13	1499967.BAYZ01000055_gene4854	1.189e-73	253.0	COG0454@1|root,COG1051@1|root,COG0456@2|Bacteria,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	yjhB	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	Acetyltransf_1,NUDIX,Nudix_N
WLSH2_k127_4396562_23	649747.HMPREF0083_04015	2.404e-23	106.0	COG1051@1|root,COG1051@2|Bacteria,1V58Q@1239|Firmicutes,4HHYE@91061|Bacilli,26Y6Z@186822|Paenibacillaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like,NUDIX
WLSH2_k127_4396562_20	926550.CLDAP_05380	3.647e-29	123.0	COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
WLSH2_k127_4396562_14	5693.XP_811898.1	1.691e-62	221.0	COG0461@1|root,KOG1377@2759|Eukaryota,3XSWC@5653|Kinetoplastida	5653|Kinetoplastida	F	Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase	-	-	2.4.2.10,4.1.1.23	ko:K01591,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase,Pribosyltran
WLSH2_k127_4396562_10	112098.XP_008611139.1	2.621e-91	308.0	COG0461@1|root,KOG1377@2759|Eukaryota	2759|Eukaryota	F	'de novo' UMP biosynthetic process	URA5	GO:0003674,GO:0003824,GO:0004588,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.1.1.202,2.4.2.10,4.1.1.23	ko:K00762,ko:K01591,ko:K13421,ko:K15334	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00051	R00965,R01870,R08231	RC00063,RC00409,RC00611	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	OMPdecase,Pribosyltran
WLSH2_k127_4396562_7	130081.XP_005704774.1	1.469e-123	404.0	COG0122@1|root,COG0458@1|root,KOG0370@2759|Eukaryota,KOG2875@2759|Eukaryota	2759|Eukaryota	L	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	URA2	GO:0000050,GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006220,GO:0006244,GO:0006259,GO:0006281,GO:0006282,GO:0006284,GO:0006285,GO:0006289,GO:0006304,GO:0006355,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0008652,GO:0009056,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009166,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009889,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010605,GO:0016020,GO:0016021,GO:0016053,GO:0016363,GO:0016604,GO:0016607,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019104,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019627,GO:0019637,GO:0019692,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0031326,GO:0031974,GO:0031981,GO:0032356,GO:0032357,GO:0032991,GO:0033554,GO:0033683,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045007,GO:0045008,GO:0045738,GO:0045934,GO:0045984,GO:0046112,GO:0046386,GO:0046394,GO:0046434,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051252,GO:0051716,GO:0055086,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0070013,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0072529,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901135,GO:1901136,GO:1901291,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2000779,GO:2000780,GO:2001020,GO:2001021,GO:2001141	2.1.3.2,3.5.2.3,4.2.99.18,6.3.5.5	ko:K01954,ko:K01955,ko:K03660,ko:K11540,ko:K11541,ko:K19656	ko00240,ko00250,ko01100,ko03410,map00240,map00250,map01100,map03410	M00051	R00256,R00575,R01395,R01397,R01993,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000,ko01002,ko03036,ko03400	-	-	-	CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,HhH-GPD,MGS,OGG_N,OTCace,OTCace_N
WLSH2_k127_4396562_22	1121382.JQKG01000100_gene2827	8.81e-25	111.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_33
WLSH2_k127_4396562_24	85643.Tmz1t_1065	1.072e-20	96.0	COG1569@1|root,COG1569@2|Bacteria,1N9YY@1224|Proteobacteria,2VWAY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WLSH2_k127_4396562_35	1041146.ATZB01000023_gene2630	0.0009538	45.0	COG2161@1|root,COG2161@2|Bacteria,1NE31@1224|Proteobacteria,2UI5J@28211|Alphaproteobacteria,4BGNG@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WLSH2_k127_4396562_5	8128.ENSONIP00000019868	1.925e-138	449.0	COG0458@1|root,KOG0370@2759|Eukaryota,38CAC@33154|Opisthokonta,3B9FF@33208|Metazoa,3CS9A@33213|Bilateria,4804V@7711|Chordata,490QX@7742|Vertebrata,49UJ7@7898|Actinopterygii	33208|Metazoa	F	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	CAD	GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905	2.1.3.2,3.5.2.3,6.3.5.5	ko:K11540	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R01397,R01993,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00632,RC02750,RC02798,RC02850,RC03314	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Amidohydro_1,CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS,OTCace,OTCace_N
WLSH2_k127_4396562_18	1185876.BN8_05600	1.735e-48	183.0	COG0697@1|root,COG0697@2|Bacteria,4NIDP@976|Bacteroidetes,47P0K@768503|Cytophagia	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_4396562_4	644966.Tmar_1473	4e-149	485.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,3WCXZ@538999|Clostridiales incertae sedis	186801|Clostridia	F	Permease family	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
WLSH2_k127_4396562_1	1192034.CAP_3742	3.162e-214	674.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WLSH2_k127_4396562_31	498761.HM1_0696	2.736e-06	60.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K00406,ko:K03889	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00151,M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
WLSH2_k127_4396562_25	237368.SCABRO_01591	6.216e-15	88.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2IX9E@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b subunit of the bc complex	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B
WLSH2_k127_4396562_12	330214.NIDE3889	6.856e-74	254.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
WLSH2_k127_4396562_21	234267.Acid_6209	3.381e-26	115.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
WLSH2_k127_4396562_32	926569.ANT_22170	5.09e-06	53.0	COG2009@1|root,COG2009@2|Bacteria,2G7CW@200795|Chloroflexi	200795|Chloroflexi	C	succinate dehydrogenase, cytochrome	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WLSH2_k127_4396562_34	1064537.AGSO01000002_gene405	0.0008582	48.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,4FCRN@85020|Dermabacteraceae	201174|Actinobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WLSH2_k127_4396562_0	926569.ANT_22150	3.374e-287	892.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WLSH2_k127_4396562_8	926569.ANT_22140	5.728e-106	347.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
WLSH2_k127_4396562_29	1038858.AXBA01000013_gene2398	3.662e-09	60.0	COG2929@1|root,COG2929@2|Bacteria,1N83Z@1224|Proteobacteria,2UGAH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
WLSH2_k127_4396562_19	1469607.KK073768_gene1852	6.976e-33	130.0	COG3514@1|root,COG3514@2|Bacteria,1G8GN@1117|Cyanobacteria,1HU2E@1161|Nostocales	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
WLSH2_k127_4396562_2	1278073.MYSTI_03346	8.243e-198	630.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,42Q1B@68525|delta/epsilon subdivisions,2WKJH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WLSH2_k127_4396562_3	45351.EDO47839	7.307e-152	494.0	COG0076@1|root,KOG1383@2759|Eukaryota,38BZ3@33154|Opisthokonta,3B9JG@33208|Metazoa	33208|Metazoa	E	sphinganine-1-phosphate aldolase activity	SGPL1	GO:0000003,GO:0001501,GO:0001553,GO:0001568,GO:0001570,GO:0001655,GO:0001667,GO:0001822,GO:0001944,GO:0002376,GO:0002520,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006672,GO:0006807,GO:0006915,GO:0006928,GO:0006950,GO:0006952,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007283,GO:0007525,GO:0007527,GO:0007548,GO:0008117,GO:0008150,GO:0008152,GO:0008202,GO:0008209,GO:0008210,GO:0008219,GO:0008406,GO:0008584,GO:0008585,GO:0008610,GO:0009056,GO:0009058,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009791,GO:0009887,GO:0009987,GO:0010171,GO:0010761,GO:0010817,GO:0012501,GO:0012505,GO:0016020,GO:0016021,GO:0016042,GO:0016477,GO:0016829,GO:0016830,GO:0016832,GO:0019752,GO:0019953,GO:0022414,GO:0022602,GO:0023052,GO:0030097,GO:0030148,GO:0030149,GO:0030154,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033327,GO:0034641,GO:0034754,GO:0035239,GO:0035295,GO:0040008,GO:0040011,GO:0040014,GO:0042175,GO:0042445,GO:0042698,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045137,GO:0046466,GO:0046467,GO:0046545,GO:0046546,GO:0046660,GO:0046661,GO:0048008,GO:0048232,GO:0048511,GO:0048513,GO:0048514,GO:0048534,GO:0048608,GO:0048609,GO:0048638,GO:0048705,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050830,GO:0050896,GO:0051179,GO:0051239,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0060021,GO:0060322,GO:0060323,GO:0060324,GO:0060325,GO:0061061,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072001,GO:0072358,GO:0072359,GO:0097190,GO:0098542,GO:0098827,GO:1901360,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	4.1.2.27	ko:K01634,ko:K20704	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	Pyridoxal_deC
WLSH2_k127_4396562_11	755731.Clo1100_3357	2.452e-78	268.0	2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,36IC8@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4396562_16	123899.JPQP01000020_gene1876	1.49e-53	197.0	COG4502@1|root,COG4502@2|Bacteria,1RHWN@1224|Proteobacteria,2VT1F@28216|Betaproteobacteria,3T6A1@506|Alcaligenaceae	28216|Betaproteobacteria	F	deoxyribonucleotide catabolic process	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	NT5C
WLSH2_k127_4396562_30	1088721.NSU_4371	7.966e-07	61.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,2K56C@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
WLSH2_k127_4396562_27	926569.ANT_31290	3.036e-12	78.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
WLSH2_k127_4396562_33	880073.Calab_1891	1.68e-05	52.0	COG1366@1|root,COG1366@2|Bacteria,2NRMX@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	btrV	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
WLSH2_k127_4396562_9	56107.Cylst_5516	2.523e-93	326.0	COG2199@1|root,COG3706@2|Bacteria,1G3FB@1117|Cyanobacteria,1HM2U@1161|Nostocales	1117|Cyanobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HisKA_7TM,PAS_4,PAS_8
WLSH2_k127_4396562_6	316274.Haur_2134	2.541e-131	425.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
WLSH2_k127_4396562_17	926569.ANT_11150	1.461e-51	191.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi	200795|Chloroflexi	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
WLSH2_k127_4396562_28	1321778.HMPREF1982_02132	3.416e-12	68.0	2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4402004_9	485913.Krac_1500	4.861e-35	149.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	ko:K02529,ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022,ko03000	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,TniQ
WLSH2_k127_4402004_6	886293.Sinac_4258	2.214e-53	199.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WLSH2_k127_4402004_14	1565129.JSFF01000008_gene2692	1.077e-09	66.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,1S6S0@1236|Gammaproteobacteria,2QBST@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WLSH2_k127_4402004_10	926569.ANT_26900	3.6e-23	114.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	4.6.1.13	ko:K01771	ko00562,map00562	-	R03332	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PD40,PI-PLC-X
WLSH2_k127_4402004_8	926569.ANT_26890	1.151e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WLSH2_k127_4402004_7	1197906.CAJQ02000047_gene4077	3.182e-39	148.0	COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4402004_5	1173264.KI913949_gene2454	1.427e-63	221.0	COG0703@1|root,COG0703@2|Bacteria	2|Bacteria	F	shikimate kinase activity	cas2	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	6PF2K,AAA_33,His_Phos_1,SKI
WLSH2_k127_4402004_3	101510.RHA1_ro02599	3.281e-104	347.0	COG1028@1|root,COG1028@2|Bacteria,2GKI2@201174|Actinobacteria,4FUVW@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WLSH2_k127_4402004_4	1408254.T458_09100	1.49e-91	312.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WLSH2_k127_4402004_2	485913.Krac_0278	1.553e-111	368.0	COG0604@1|root,COG0604@2|Bacteria,2G84Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WLSH2_k127_4402004_11	329726.AM1_6084	1.455e-19	102.0	2DNVA@1|root,32ZBE@2|Bacteria,1GFXX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4402004_1	42256.RradSPS_0358	8.542e-201	657.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_4402004_12	102125.Xen7305DRAFT_00047110	3.429e-19	92.0	arCOG06733@1|root,32HH3@2|Bacteria,1G77Z@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4402004_0	42256.RradSPS_0358	1.355e-250	801.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_4402004_15	324602.Caur_3820	6.874e-08	60.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
WLSH2_k127_4417186_10	765913.ThidrDRAFT_2509	1.641e-38	150.0	2F1SA@1|root,33USF@2|Bacteria,1NVHZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4417186_12	485913.Krac_1423	3.9e-27	113.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
WLSH2_k127_4417186_19	485913.Krac_4022	3.189e-08	58.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
WLSH2_k127_4417186_16	1267535.KB906767_gene1220	1.412e-11	66.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
WLSH2_k127_4417186_18	485913.Krac_4022	3.358e-09	58.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
WLSH2_k127_4417186_14	365046.Rta_19270	2.894e-24	109.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJR2@28216|Betaproteobacteria,4ABHZ@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9,Response_reg
WLSH2_k127_4417186_8	1128421.JAGA01000002_gene1765	4.611e-56	203.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
WLSH2_k127_4417186_15	383372.Rcas_1314	6.313e-15	78.0	2BRHQ@1|root,32KGQ@2|Bacteria,2GB33@200795|Chloroflexi,377U1@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4417186_5	383372.Rcas_1313	1.278e-69	241.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WLSH2_k127_4417186_2	663278.Ethha_0807	6.795e-121	405.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WLSH2_k127_4417186_7	1122917.KB899661_gene961	4.825e-63	228.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli,26QBG@186822|Paenibacillaceae	91061|Bacilli	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WLSH2_k127_4417186_4	1304875.JAFZ01000003_gene624	1.194e-76	267.0	COG1079@1|root,COG1079@2|Bacteria,3TAFP@508458|Synergistetes	508458|Synergistetes	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WLSH2_k127_4417186_11	1122917.KB899661_gene959	1.261e-33	140.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HF7R@91061|Bacilli,26QEK@186822|Paenibacillaceae	91061|Bacilli	S	membrane	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WLSH2_k127_4417186_20	1128421.JAGA01000002_gene732	9.853e-07	51.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K06400,ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH2_k127_4417186_3	565045.NOR51B_339	7.72e-106	355.0	COG1028@1|root,COG1028@2|Bacteria	565045.NOR51B_339|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4417186_9	91464.S7335_4523	2.112e-50	187.0	COG0702@1|root,COG0702@2|Bacteria,1G3PB@1117|Cyanobacteria	1117|Cyanobacteria	GM	PFAM NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WLSH2_k127_4417186_17	240302.BN982_00483	7.862e-11	68.0	COG1846@1|root,COG1846@2|Bacteria,1VACT@1239|Firmicutes,4HHUZ@91061|Bacilli,3NETZ@45667|Halobacillus	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	ysmB	-	-	-	-	-	-	-	-	-	-	-	MarR
WLSH2_k127_4417186_0	261292.Nit79A3_1514	1.959e-311	983.0	COG0383@1|root,COG0383@2|Bacteria,1R3Q8@1224|Proteobacteria	1224|Proteobacteria	G	Alpha-Mannosidase	mngB	GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	iEcolC_1368.EcolC_2924,iSF_1195.SF0565,iSFxv_1172.SFxv_0623,iS_1188.S0578	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WLSH2_k127_4417186_6	1122927.KB895426_gene286	8.288e-67	245.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2,MFS_3
WLSH2_k127_4417186_1	1304880.JAGB01000003_gene1278	8.777e-219	692.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WLSH2_k127_4441602_8	985054.JQEZ01000003_gene1553	0.0001042	53.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,2UC1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
WLSH2_k127_4441602_7	1539298.JO41_05245	1.445e-07	63.0	COG0824@1|root,COG0824@2|Bacteria,2J837@203691|Spirochaetes	203691|Spirochaetes	S	acyl-CoA thioester hydrolase, YbgC YbaW family	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
WLSH2_k127_4441602_6	324602.Caur_1140	6.34e-46	181.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GGDEF,HAMP
WLSH2_k127_4441602_1	324602.Caur_2785	4.927e-90	305.0	COG4242@1|root,COG4242@2|Bacteria,2G8XH@200795|Chloroflexi,377A4@32061|Chloroflexia	32061|Chloroflexia	PQ	PFAM peptidase S51 dipeptidase E	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WLSH2_k127_4441602_3	324602.Caur_2782	9.833e-76	265.0	COG1173@1|root,COG1173@2|Bacteria,2G853@200795|Chloroflexi	200795|Chloroflexi	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WLSH2_k127_4441602_2	1382356.JQMP01000003_gene2440	1.376e-80	281.0	COG0601@1|root,COG0601@2|Bacteria,2GA2P@200795|Chloroflexi,27YUQ@189775|Thermomicrobia	189775|Thermomicrobia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_4441602_5	1229172.JQFA01000002_gene3019	1.904e-60	232.0	COG0747@1|root,COG0747@2|Bacteria,1G0S3@1117|Cyanobacteria,1H75X@1150|Oscillatoriales	1117|Cyanobacteria	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_4441602_0	234267.Acid_6598	3.398e-103	351.0	COG4242@1|root,COG4242@2|Bacteria,3Y6RX@57723|Acidobacteria	57723|Acidobacteria	M	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
WLSH2_k127_4441602_4	324602.Caur_2786	1.056e-75	260.0	COG1802@1|root,COG1802@2|Bacteria,2G993@200795|Chloroflexi,377MM@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WLSH2_k127_4508042_2	1033810.HLPCO_001723	8.357e-59	211.0	COG1028@1|root,COG1028@2|Bacteria	1033810.HLPCO_001723|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4508042_1	926569.ANT_02760	9.476e-80	273.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_4508042_3	1033810.HLPCO_000861	5.692e-49	183.0	COG0500@1|root,COG2226@2|Bacteria,2NQ2E@2323|unclassified Bacteria	2|Bacteria	Q	Methionine biosynthesis protein MetW	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
WLSH2_k127_4508042_6	1173023.KE650771_gene1773	1.482e-11	66.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2929 conserved	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
WLSH2_k127_4508042_5	1499967.BAYZ01000170_gene5514	1.808e-22	98.0	2C6B2@1|root,335GA@2|Bacteria,2NRFZ@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4508042_4	99598.Cal7507_5432	1.113e-23	113.0	28T2A@1|root,2ZFBG@2|Bacteria,1GIG3@1117|Cyanobacteria,1HKCI@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4508042_0	311424.DhcVS_1416	4.056e-81	274.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,34CKH@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_4510565_3	1173026.Glo7428_1794	8.712e-42	162.0	COG4106@1|root,COG4106@2|Bacteria,1GQEP@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH2_k127_4510565_8	1321774.HMPREF9108_02380	1.095e-08	63.0	COG0454@1|root,COG0456@2|Bacteria,37B90@32066|Fusobacteria	32066|Fusobacteria	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
WLSH2_k127_4510565_0	247490.KSU1_C1112	3.25e-150	488.0	COG0312@1|root,COG0312@2|Bacteria,2J2IZ@203682|Planctomycetes	203682|Planctomycetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
WLSH2_k127_4510565_2	255470.cbdbA494	1.731e-93	323.0	COG0312@1|root,COG0312@2|Bacteria,2GANY@200795|Chloroflexi,34CWZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH2_k127_4510565_9	1254432.SCE1572_34605	0.0002695	49.0	COG3464@1|root,COG3464@2|Bacteria,1NPPU@1224|Proteobacteria,43BG7@68525|delta/epsilon subdivisions,2X6UI@28221|Deltaproteobacteria,2Z33P@29|Myxococcales	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4510565_4	1254432.SCE1572_39920	9.418e-42	158.0	COG3464@1|root,COG3464@2|Bacteria,1NPPU@1224|Proteobacteria,43BG7@68525|delta/epsilon subdivisions,2X6UI@28221|Deltaproteobacteria,2Z33P@29|Myxococcales	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4510565_5	1027273.GZ77_25575	7.57e-19	93.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
WLSH2_k127_4510565_7	1123400.KB904769_gene2917	1.335e-11	71.0	COG3038@1|root,COG3038@2|Bacteria	2|Bacteria	C	cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	DUF3611,Ni_hydr_CYTB
WLSH2_k127_4510565_1	926569.ANT_11970	1.828e-119	393.0	COG1148@1|root,COG1148@2|Bacteria,2G7GY@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4517509_12	926560.KE387023_gene2131	2.522e-98	325.0	COG3694@1|root,COG3694@2|Bacteria,1WM9D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_6
WLSH2_k127_4517509_21	313596.RB2501_12022	2.283e-40	163.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WLSH2_k127_4517509_35	1385935.N836_17870	1.079e-14	78.0	COG1669@1|root,COG1669@2|Bacteria,1GQ89@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH2_k127_4517509_32	195253.Syn6312_2069	3.852e-18	86.0	COG1895@1|root,COG1895@2|Bacteria,1G7UH@1117|Cyanobacteria,1H17K@1129|Synechococcus	1117|Cyanobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
WLSH2_k127_4517509_30	4792.ETI40201	4.47e-22	108.0	COG2340@1|root,2SNRF@2759|Eukaryota,3QARB@4776|Peronosporales	4776|Peronosporales	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
WLSH2_k127_4517509_31	926569.ANT_22190	7.158e-20	101.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_4517509_34	357808.RoseRS_4591	1.506e-15	88.0	COG2340@1|root,COG2340@2|Bacteria,2GA1I@200795|Chloroflexi,377J5@32061|Chloroflexia	32061|Chloroflexia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
WLSH2_k127_4517509_28	926569.ANT_22190	1.482e-24	116.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_4517509_6	926569.ANT_25740	9.819e-142	480.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
WLSH2_k127_4517509_15	926569.ANT_12120	5.587e-94	322.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1
WLSH2_k127_4517509_4	316274.Haur_3367	2.59e-187	593.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,374ZW@32061|Chloroflexia	32061|Chloroflexia	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
WLSH2_k127_4517509_18	1041930.Mtc_0845	3.26e-50	195.0	COG0642@1|root,arCOG02338@1|root,arCOG02338@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,2NBMD@224756|Methanomicrobia	224756|Methanomicrobia	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WLSH2_k127_4517509_29	926569.ANT_20810	7.601e-24	104.0	COG4818@1|root,COG4818@2|Bacteria,2G9PA@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
WLSH2_k127_4517509_8	926569.ANT_20820	4.397e-121	395.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi	200795|Chloroflexi	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WLSH2_k127_4517509_16	331678.Cphamn1_1646	9.713e-68	234.0	COG1592@1|root,COG1592@2|Bacteria,1FE9N@1090|Chlorobi	1090|Chlorobi	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH2_k127_4517509_33	1121104.AQXH01000001_gene1984	7.971e-17	87.0	COG1510@1|root,COG1510@2|Bacteria,4NQPD@976|Bacteroidetes,1ISGU@117747|Sphingobacteriia	976|Bacteroidetes	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,MarR_2,TrmB
WLSH2_k127_4517509_11	1382306.JNIM01000001_gene787	1.645e-99	334.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
WLSH2_k127_4517509_22	344747.PM8797T_27190	3.432e-39	153.0	COG0551@1|root,COG0551@2|Bacteria,2J0R7@203682|Planctomycetes	203682|Planctomycetes	L	PFAM DNA topoisomerase type IA zn finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726,zf-C4_Topoisom
WLSH2_k127_4517509_13	926569.ANT_10620	1.728e-96	331.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi	200795|Chloroflexi	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
WLSH2_k127_4517509_36	857087.Metme_4103	1.709e-10	68.0	2EH3D@1|root,33AVD@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
WLSH2_k127_4517509_24	765420.OSCT_1320	1.239e-30	124.0	COG1694@1|root,COG1694@2|Bacteria,2G9Y9@200795|Chloroflexi,377WH@32061|Chloroflexia	32061|Chloroflexia	F	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
WLSH2_k127_4517509_19	926569.ANT_14050	6.971e-50	183.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WLSH2_k127_4517509_2	926569.ANT_10600	4.957e-233	730.0	COG0442@1|root,COG0442@2|Bacteria,2G636@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
WLSH2_k127_4517509_23	56780.SYN_00801	6.41e-38	147.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0034641,GO:0042365,GO:0042737,GO:0042802,GO:0042803,GO:0042816,GO:0042820,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046983,GO:0047411,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.1.29	ko:K07020,ko:K18614	ko00750,ko01120,map00750,map01120	-	R01649	RC00300,RC00575	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_5,Abhydrolase_6,LIP,UPF0227
WLSH2_k127_4517509_5	204669.Acid345_3113	1.178e-148	482.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WLSH2_k127_4517509_0	1035308.AQYY01000001_gene1943	8.32e-314	971.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24BRX@186801|Clostridia,260H8@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WLSH2_k127_4517509_20	1191523.MROS_0663	1.374e-46	178.0	COG3358@1|root,COG3358@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
WLSH2_k127_4517509_17	1340493.JNIF01000003_gene2717	8.858e-61	220.0	COG3358@1|root,COG3358@2|Bacteria,3Y4K1@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
WLSH2_k127_4517509_7	658655.HMPREF0988_02499	1.948e-141	454.0	COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,24D3T@186801|Clostridia,27JTP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
WLSH2_k127_4517509_9	1499683.CCFF01000016_gene904	3.086e-120	391.0	COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,24AYK@186801|Clostridia,36E9T@31979|Clostridiaceae	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
WLSH2_k127_4517509_1	1499683.CCFF01000016_gene905	2.014e-283	879.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,36F82@31979|Clostridiaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
WLSH2_k127_4517509_14	1499683.CCFF01000016_gene906	9.062e-95	314.0	COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,24GT3@186801|Clostridia,36FG5@31979|Clostridiaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16924	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.29	-	-	ECF-ribofla_trS
WLSH2_k127_4517509_10	485913.Krac_2372	4.674e-111	371.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4517509_25	574375.BAGA_25365	5.494e-28	121.0	COG0454@1|root,COG0456@2|Bacteria,1V9XN@1239|Firmicutes,4IRM3@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WLSH2_k127_4517509_37	1408310.JHUW01000007_gene372	0.0007178	45.0	COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,2FTV5@200643|Bacteroidia	976|Bacteroidetes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH2_k127_4517509_3	926569.ANT_02040	1.325e-214	676.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
WLSH2_k127_454162_11	1321778.HMPREF1982_02132	6.219e-05	47.0	2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_454162_5	926569.ANT_28370	5.057e-54	199.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WLSH2_k127_454162_1	926569.ANT_28360	1.447e-91	306.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
WLSH2_k127_454162_2	479434.Sthe_0612	2.997e-89	308.0	COG0265@1|root,COG0265@2|Bacteria,2G8RK@200795|Chloroflexi,27Y6G@189775|Thermomicrobia	200795|Chloroflexi	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	1.3.1.74,3.4.21.107	ko:K04771,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_454162_3	926569.ANT_01690	9.8e-73	250.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WLSH2_k127_454162_6	90371.CY43_16055	6.75e-53	196.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_454162_9	1250005.PHEL85_1063	1.951e-14	81.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,1HXTK@117743|Flavobacteriia,3VVYS@52959|Polaribacter	976|Bacteroidetes	E	Peptidase family S51	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WLSH2_k127_454162_7	926569.ANT_30190	5.331e-37	143.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH2_k127_454162_0	926569.ANT_15910	9.727e-236	736.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WLSH2_k127_454162_4	926569.ANT_15910	1.026e-54	197.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WLSH2_k127_454162_8	870187.Thini_2788	2.578e-30	122.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,4615Y@72273|Thiotrichales	72273|Thiotrichales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WLSH2_k127_4580560_3	357808.RoseRS_4004	1.008e-87	301.0	COG4597@1|root,COG4597@2|Bacteria,2G7PM@200795|Chloroflexi,376AX@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
WLSH2_k127_4580560_2	1128421.JAGA01000002_gene1952	3.592e-114	380.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09969	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
WLSH2_k127_4580560_5	926569.ANT_11330	5.236e-52	188.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WLSH2_k127_4580560_9	1408428.JNJP01000051_gene3814	9.185e-06	54.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,2MB9P@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM Cyclic nucleotide-binding	fnr-1	-	-	ko:K01420,ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_4580560_0	926550.CLDAP_39810	2.469e-229	731.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi	200795|Chloroflexi	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WLSH2_k127_4580560_1	926569.ANT_16690	1.468e-115	385.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WLSH2_k127_4580560_8	240015.ACP_3002	7.092e-12	71.0	COG4243@1|root,COG4243@2|Bacteria,3Y4UT@57723|Acidobacteria,2JJIW@204432|Acidobacteriia	204432|Acidobacteriia	S	Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
WLSH2_k127_4580560_4	326427.Cagg_2787	7.278e-63	225.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WLSH2_k127_4580560_6	324602.Caur_2581	6.103e-42	159.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4581771_7	1122925.KB895387_gene2807	0.0005538	45.0	2DREZ@1|root,33BFB@2|Bacteria,1UPXP@1239|Firmicutes,4IVCS@91061|Bacilli,2743X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4581771_1	926569.ANT_06130	9.442e-101	340.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,LysM,YkuD
WLSH2_k127_4581771_5	926569.ANT_03760	4.101e-58	205.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
WLSH2_k127_4581771_4	926569.ANT_03770	2.36e-88	295.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
WLSH2_k127_4581771_2	926569.ANT_03780	3.475e-97	326.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	2|Bacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
WLSH2_k127_4581771_3	926569.ANT_03790	2.234e-96	321.0	COG0463@1|root,COG0463@2|Bacteria,2GBP0@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WLSH2_k127_4581771_0	926569.ANT_03800	1.124e-101	338.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WLSH2_k127_4581771_6	1034345.CAEM01000001_gene448	1.733e-24	116.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,4CVBG@84998|Coriobacteriia	84998|Coriobacteriia	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
WLSH2_k127_4604745_14	1254432.SCE1572_44715	2.939e-11	65.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WLSH2_k127_4604745_17	448385.sce7758	2.468e-08	57.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WLSH2_k127_4604745_2	1382306.JNIM01000001_gene1873	7.868e-76	272.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
WLSH2_k127_4604745_7	1294265.JCM21738_500	3.723e-35	139.0	COG4852@1|root,COG4852@2|Bacteria,1VBU5@1239|Firmicutes,4HM77@91061|Bacilli	91061|Bacilli	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
WLSH2_k127_4604745_10	1267535.KB906767_gene573	1.532e-15	90.0	COG0823@1|root,COG0823@2|Bacteria,3Y2RC@57723|Acidobacteria,2JIV3@204432|Acidobacteriia	204432|Acidobacteriia	U	WD40-like Beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WLSH2_k127_4604745_18	1121272.KB903254_gene6700	1.279e-07	64.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Peptidase_C14,TIR_2,TPR_10,WD40
WLSH2_k127_4604745_6	926569.ANT_00330	5.255e-37	149.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WLSH2_k127_4604745_4	926569.ANT_29880	4.679e-56	199.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WLSH2_k127_4604745_0	926550.CLDAP_01130	1.801e-165	536.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WLSH2_k127_4604745_12	1144275.COCOR_03426	1.502e-12	74.0	COG0222@1|root,COG0222@2|Bacteria	2|Bacteria	J	mitochondrial gene expression	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WLSH2_k127_4604745_3	926569.ANT_29500	1.071e-67	237.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_4604745_16	1521187.JPIM01000032_gene1982	1.348e-09	69.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi	200795|Chloroflexi	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WLSH2_k127_4604745_5	926569.ANT_29480	5.01e-52	188.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi	200795|Chloroflexi	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_4604745_1	926569.ANT_07440	2.066e-92	311.0	COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
WLSH2_k127_4604745_13	591159.ACEZ01000226_gene1065	4.421e-12	75.0	2E9YS@1|root,3344A@2|Bacteria,2IJZ5@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
WLSH2_k127_4604745_11	713587.THITH_11150	2.929e-13	80.0	29YCS@1|root,30K75@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4604745_9	926569.ANT_28860	1.036e-22	101.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi	200795|Chloroflexi	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WLSH2_k127_4612290_3	1121926.AXWO01000025_gene3894	7.944e-10	60.0	COG1846@1|root,COG1846@2|Bacteria,2IRGU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
WLSH2_k127_4612290_1	1173027.Mic7113_5589	1.325e-44	168.0	COG1051@1|root,COG1051@2|Bacteria,1GBA9@1117|Cyanobacteria,1HGUB@1150|Oscillatoriales	1117|Cyanobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_4612290_0	404589.Anae109_3135	5.874e-70	242.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WLSH2_k127_4630758_3	749414.SBI_05196	9.568e-94	338.0	COG2274@1|root,COG2319@1|root,COG2274@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,HTH_3,HTH_31,WD40
WLSH2_k127_4630758_5	746697.Aeqsu_2868	1.373e-64	252.0	COG3210@1|root,COG3210@2|Bacteria,4NGEX@976|Bacteroidetes,1HZV9@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4630758_10	1540257.JQMW01000011_gene1672	1.062e-24	104.0	2BAPB@1|root,32448@2|Bacteria,1UQGX@1239|Firmicutes,24TXP@186801|Clostridia,36NES@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4630758_4	935948.KE386495_gene1232	6.222e-93	312.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,42IG4@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
WLSH2_k127_4630758_14	1047013.AQSP01000140_gene2469	8.929e-08	53.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WLSH2_k127_4630758_2	290317.Cpha266_1585	3.855e-108	359.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	DUF1735,Laminin_G_3,Patatin
WLSH2_k127_4630758_0	945713.IALB_2868	1.227e-246	769.0	COG2986@1|root,COG2986@2|Bacteria	2|Bacteria	E	ammonia-lyase activity	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WLSH2_k127_4630758_8	530564.Psta_3376	7.363e-31	126.0	COG0454@1|root,COG1181@1|root,COG0456@2|Bacteria,COG1181@2|Bacteria,2IZEV@203682|Planctomycetes	203682|Planctomycetes	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WLSH2_k127_4630758_9	395961.Cyan7425_0492	1.049e-28	118.0	COG1396@1|root,COG1396@2|Bacteria,1GGP9@1117|Cyanobacteria	1117|Cyanobacteria	K	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
WLSH2_k127_4630758_1	926569.ANT_22380	9.726e-162	516.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.97	ko:K01190,ko:K17624	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH101	-	DUF2804
WLSH2_k127_4630758_12	479434.Sthe_3506	1.94e-15	85.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2G7EW@200795|Chloroflexi	200795|Chloroflexi	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
WLSH2_k127_4630758_13	1071073.KI530537_gene1485	6.799e-13	79.0	COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli,1ZC4H@1386|Bacillus	91061|Bacilli	M	Phosphotransferase	ytmP	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_4630758_11	267608.RSp0476	5.746e-17	94.0	COG3209@1|root,COG4105@1|root,COG3209@2|Bacteria,COG4105@2|Bacteria,1MVV1@1224|Proteobacteria,2VMJI@28216|Betaproteobacteria,1K0C1@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Rhs_assc_core RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PAAR_motif,Peptidase_C39,RHS,RHS_repeat
WLSH2_k127_4630758_7	1313172.YM304_08050	2.067e-43	177.0	2DFIR@1|root,2ZS07@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4630758_15	1320556.AVBP01000001_gene4425	1.242e-05	49.0	COG4331@1|root,COG4331@2|Bacteria,1RGSA@1224|Proteobacteria,2U713@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
WLSH2_k127_4630758_6	479434.Sthe_3401	5.039e-60	216.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_4641709_2	926569.ANT_07670	7.677e-68	239.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH2_k127_4641709_1	926569.ANT_07660	8.995e-100	330.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_4641709_0	926569.ANT_07650	3.208e-182	578.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_4641709_3	926569.ANT_07670	3.634e-53	202.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH2_k127_4669509_17	661478.OP10G_4419	1.153e-44	169.0	COG4420@1|root,COG4420@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
WLSH2_k127_4669509_13	926550.CLDAP_21010	1.307e-63	238.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WLSH2_k127_4669509_12	926550.CLDAP_21020	3.525e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_4669509_30	1229780.BN381_70067	1.25e-08	61.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_4669509_24	365046.Rta_32680	1.154e-20	95.0	COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,2VWCP@28216|Betaproteobacteria,4AINA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WLSH2_k127_4669509_27	479434.Sthe_2550	1.009e-14	80.0	COG0762@1|root,COG0762@2|Bacteria,2G9JK@200795|Chloroflexi,27ZAJ@189775|Thermomicrobia	189775|Thermomicrobia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4669509_25	317936.Nos7107_3521	2.577e-20	97.0	2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HS5Z@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4669509_8	1128421.JAGA01000002_gene1281	1.985e-79	281.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WLSH2_k127_4669509_15	316274.Haur_2801	6.853e-59	220.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WLSH2_k127_4669509_18	103690.17135394	2.17e-38	153.0	28PC1@1|root,2ZC4I@2|Bacteria,1G51C@1117|Cyanobacteria,1HRFP@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4669509_0	926569.ANT_15550	5.162e-214	675.0	COG1032@1|root,COG1032@2|Bacteria,2G6X0@200795|Chloroflexi	200795|Chloroflexi	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
WLSH2_k127_4669509_20	1499967.BAYZ01000036_gene2415	6.379e-35	136.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WLSH2_k127_4669509_33	383372.Rcas_0224	3.95e-05	46.0	COG2010@1|root,COG2010@2|Bacteria,2G6R3@200795|Chloroflexi,377DZ@32061|Chloroflexia	32061|Chloroflexia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
WLSH2_k127_4669509_14	102129.Lepto7375DRAFT_1723	3.735e-59	214.0	2BQFG@1|root,32JAW@2|Bacteria,1GF3H@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4669509_4	983917.RGE_14420	9.107e-121	400.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2VQB6@28216|Betaproteobacteria,1KNAK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
WLSH2_k127_4669509_5	1173025.GEI7407_2445	1.25e-102	349.0	COG2211@1|root,COG2211@2|Bacteria,1G0ZY@1117|Cyanobacteria,1H6Y4@1150|Oscillatoriales	1117|Cyanobacteria	G	COG2211 Na melibiose symporter and related	melB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_4669509_11	1125863.JAFN01000001_gene418	2.797e-70	257.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42N1X@68525|delta/epsilon subdivisions,2WKMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase MttB (TMA methyltransferase)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_4669509_6	935845.JADQ01000020_gene4166	4.137e-90	317.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_4669509_7	2325.TKV_c10210	3.23e-85	291.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,42FXH@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	nikB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_4669509_9	479434.Sthe_3429	5.15e-78	273.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi,27Y61@189775|Thermomicrobia	189775|Thermomicrobia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WLSH2_k127_4669509_1	926550.CLDAP_01180	1.701e-180	579.0	COG1574@1|root,COG1574@2|Bacteria	2|Bacteria	G	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WLSH2_k127_4669509_26	700508.D174_19525	5.891e-16	89.0	COG4221@1|root,COG4221@2|Bacteria,2GP05@201174|Actinobacteria,233G0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_4669509_16	1123519.PSJM300_17900	1.502e-51	188.0	COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria,1SGBM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WLSH2_k127_4669509_21	1134413.ANNK01000134_gene3113	7.565e-35	140.0	28PN2@1|root,2ZCAV@2|Bacteria,1V2C1@1239|Firmicutes,4HGS6@91061|Bacilli,1ZG8V@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4669509_28	565033.GACE_0632	9.42e-11	70.0	COG2020@1|root,arCOG03580@2157|Archaea,2XXNN@28890|Euryarchaeota	28890|Euryarchaeota	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WLSH2_k127_4669509_23	1499967.BAYZ01000019_gene6321	1.618e-21	98.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	MIase
WLSH2_k127_4669509_2	926550.CLDAP_13780	5.18e-180	572.0	COG2311@1|root,COG2311@2|Bacteria,2G8B7@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
WLSH2_k127_4669509_3	470704.XP_007752980.1	2.249e-127	423.0	COG1233@1|root,KOG4254@2759|Eukaryota,38GIP@33154|Opisthokonta,3NY26@4751|Fungi,3QK9T@4890|Ascomycota,20GA6@147545|Eurotiomycetes,3MR5E@451870|Chaetothyriomycetidae	4751|Fungi	H	Flavin containing amine oxidoreductase	-	-	1.3.99.30	ko:K15745	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R07518,R09692	RC01214,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WLSH2_k127_4669509_31	1223544.GSI01S_06_01520	3.125e-06	59.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4GCN9@85026|Gordoniaceae	201174|Actinobacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WLSH2_k127_4669509_10	867845.KI911784_gene3077	8.63e-76	262.0	COG5522@1|root,COG5522@2|Bacteria	2|Bacteria	S	Integral membrane protein (intg_mem_TP0381)	ywaF	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
WLSH2_k127_4669509_29	2074.JNYD01000022_gene1507	3.788e-10	63.0	COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_3
WLSH2_k127_4669509_22	500635.MITSMUL_03138	5.004e-23	100.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4673030_6	266834.SM_b20078	3.289e-09	63.0	COG2197@1|root,COG2197@2|Bacteria,1RGH6@1224|Proteobacteria,2U81B@28211|Alphaproteobacteria,4BM6D@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02479,ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WLSH2_k127_4673030_5	330214.NIDE0745	1.044e-12	73.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WLSH2_k127_4673030_3	485913.Krac_9732	7.28e-46	187.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,DLH,Peptidase_S9
WLSH2_k127_4673030_2	1196323.ALKF01000149_gene1456	3.285e-96	334.0	COG1277@1|root,COG1277@2|Bacteria,1UP3Z@1239|Firmicutes,4IUZZ@91061|Bacilli,276YX@186822|Paenibacillaceae	2|Bacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4673030_0	304371.MCP_1300	7.501e-131	424.0	COG1131@1|root,arCOG00194@2157|Archaea,2XVFB@28890|Euryarchaeota,2NARP@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_4673030_1	861299.J421_6088	1.672e-117	402.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_4673030_4	485913.Krac_10496	3.05e-15	76.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WLSH2_k127_4709203_0	395019.Bmul_1166	7.204e-128	420.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2VKD6@28216|Betaproteobacteria,1K2MR@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
WLSH2_k127_4712987_1	1122222.AXWR01000002_gene2178	6.439e-98	331.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_4712987_2	1499967.BAYZ01000083_gene1022	1.247e-81	284.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	AAT,CBAH
WLSH2_k127_4712987_0	1168034.FH5T_08080	4.725e-294	915.0	COG3410@1|root,COG3410@2|Bacteria,4NGT9@976|Bacteroidetes,2FRFR@200643|Bacteroidia	976|Bacteroidetes	S	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
WLSH2_k127_4712987_3	1123073.KB899241_gene2285	1.079e-47	179.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1T7S9@1236|Gammaproteobacteria,1X9NA@135614|Xanthomonadales	135614|Xanthomonadales	Q	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WLSH2_k127_4717511_2	926550.CLDAP_10160	2.348e-151	486.0	COG0399@1|root,COG0399@2|Bacteria,2G7WW@200795|Chloroflexi	200795|Chloroflexi	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WLSH2_k127_4717511_3	768671.ThimaDRAFT_4426	3.602e-145	477.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria,1SQA0@1236|Gammaproteobacteria,1X16W@135613|Chromatiales	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4717511_11	368407.Memar_1624	2.911e-05	49.0	COG0243@1|root,arCOG01491@2157|Archaea,2XT94@28890|Euryarchaeota,2NBP4@224756|Methanomicrobia	224756|Methanomicrobia	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WLSH2_k127_4717511_9	1382306.JNIM01000001_gene47	6.498e-61	241.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1,Pentapeptide,TIR_2,WD40
WLSH2_k127_4717511_8	46234.ANA_C12002	9.154e-67	260.0	COG2319@1|root,COG4928@1|root,COG2319@2|Bacteria,COG4928@2|Bacteria,1GBPH@1117|Cyanobacteria	1117|Cyanobacteria	F	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase,WD40
WLSH2_k127_4717511_10	489825.LYNGBM3L_57750	8.472e-07	51.0	COG0644@1|root,COG0644@2|Bacteria,1G7SW@1117|Cyanobacteria,1HGCQ@1150|Oscillatoriales	1117|Cyanobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
WLSH2_k127_4717511_7	1235790.C805_02037	2.895e-69	244.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25VA9@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_4717511_6	1242864.D187_005409	7.095e-92	319.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WLSH2_k127_4717511_5	1242864.D187_005409	2.901e-94	327.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WLSH2_k127_4717511_0	211165.AJLN01000051_gene5004	2.85e-320	1035.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
WLSH2_k127_4717511_4	671143.DAMO_2121	2.472e-135	445.0	COG0635@1|root,COG2267@1|root,COG0635@2|Bacteria,COG2267@2|Bacteria,2NRGT@2323|unclassified Bacteria	2|Bacteria	H	Elongator protein 3, MiaB family, Radical SAM	estX	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4,Radical_SAM
WLSH2_k127_4717511_1	118161.KB235922_gene570	5.225e-246	807.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Sulfotransfer_3,Thioesterase,ketoacyl-synt
WLSH2_k127_4741571_10	926569.ANT_15080	2.308e-40	160.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_4741571_5	1469613.JT55_05230	3.908e-115	384.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2TSTD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WLSH2_k127_4741571_3	926569.ANT_27900	2.984e-127	418.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WLSH2_k127_4741571_0	926569.ANT_27890	1.549e-214	680.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WLSH2_k127_4741571_7	926569.ANT_28040	2.694e-102	343.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi	200795|Chloroflexi	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WLSH2_k127_4741571_9	448385.sce7758	5.349e-56	209.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WLSH2_k127_4741571_1	926569.ANT_28050	4.738e-165	529.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_4741571_6	926569.ANT_28060	2.402e-104	346.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WLSH2_k127_4741571_8	926569.ANT_00870	1.387e-95	326.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
WLSH2_k127_4741571_4	926569.ANT_00860	1.935e-126	420.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
WLSH2_k127_4741571_11	926569.ANT_26660	5.814e-37	142.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WLSH2_k127_4741571_2	926569.ANT_26670	2.932e-158	503.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WLSH2_k127_4748735_7	926569.ANT_27550	2.595e-80	274.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi	200795|Chloroflexi	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
WLSH2_k127_4748735_3	926569.ANT_27540	7.928e-105	351.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi	200795|Chloroflexi	E	homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
WLSH2_k127_4748735_2	1313301.AUGC01000001_gene1467	8.274e-141	467.0	COG0308@1|root,COG0308@2|Bacteria,4NFT0@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
WLSH2_k127_4748735_8	317936.Nos7107_3546	2.865e-56	202.0	COG0703@1|root,COG0703@2|Bacteria,1GJPH@1117|Cyanobacteria,1HS8A@1161|Nostocales	1117|Cyanobacteria	E	Shikimate kinase	-	-	-	-	-	-	-	-	-	-	-	-	SKI
WLSH2_k127_4748735_10	289376.THEYE_A1015	5.835e-47	173.0	COG0801@1|root,COG0801@2|Bacteria,3J19N@40117|Nitrospirae	40117|Nitrospirae	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
WLSH2_k127_4748735_5	1134413.ANNK01000167_gene499	2.213e-90	306.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WLSH2_k127_4748735_6	926569.ANT_19720	1.796e-88	308.0	COG1594@1|root,COG1594@2|Bacteria	2|Bacteria	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
WLSH2_k127_4748735_0	1123073.KB899241_gene2286	7.847e-270	838.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria,1X5MS@135614|Xanthomonadales	135614|Xanthomonadales	Q	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WLSH2_k127_4748735_1	1123073.KB899241_gene2287	9.558e-200	628.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X7MH@135614|Xanthomonadales	135614|Xanthomonadales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
WLSH2_k127_4748735_13	552811.Dehly_1481	2.879e-08	63.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
WLSH2_k127_4748735_4	926569.ANT_13710	4.291e-96	321.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
WLSH2_k127_4748735_9	926569.ANT_16940	2.853e-55	216.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WLSH2_k127_4748735_11	1123073.KB899242_gene1109	6.649e-36	156.0	COG1470@1|root,COG3210@1|root,COG4625@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,Haemagg_act,He_PIG,Hint_2,TIG
WLSH2_k127_4767294_0	1499967.BAYZ01000060_gene6002	4.771e-186	606.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
WLSH2_k127_4767294_5	1545915.JROG01000004_gene2589	8.941e-08	58.0	COG3631@1|root,COG3631@2|Bacteria,1NUJT@1224|Proteobacteria,2URVR@28211|Alphaproteobacteria,2KA61@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4767294_4	997346.HMPREF9374_3151	1.906e-55	223.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27B9F@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_4767294_1	1265505.ATUG01000002_gene1171	1.541e-128	450.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,434EE@68525|delta/epsilon subdivisions,2WYRT@28221|Deltaproteobacteria,2MN3I@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
WLSH2_k127_4767294_3	997346.HMPREF9374_3151	1.883e-57	226.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,27B9F@186824|Thermoactinomycetaceae	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_4767294_2	1121377.KB906402_gene3232	9.707e-109	380.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
WLSH2_k127_476952_16	1278073.MYSTI_07525	6.333e-10	65.0	COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH2_k127_476952_8	1484460.JSWG01000012_gene1367	4.902e-33	141.0	COG0642@1|root,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,1HYZK@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GAF,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_9,Response_reg,TPR_12
WLSH2_k127_476952_10	292459.STH876	4.406e-28	118.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
WLSH2_k127_476952_4	1123024.AUII01000006_gene4635	4.92e-77	277.0	2DN8B@1|root,32W2U@2|Bacteria,2ISPU@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_476952_0	1123024.AUII01000006_gene4636	0.0	1233.0	COG3696@1|root,COG3696@2|Bacteria,2I53X@201174|Actinobacteria,4EE9U@85010|Pseudonocardiales	201174|Actinobacteria	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WLSH2_k127_476952_9	1089545.KB913037_gene2299	1.997e-29	122.0	2DS99@1|root,33F32@2|Bacteria,2GXTE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_476952_13	479435.Kfla_3509	2.776e-13	82.0	COG1572@1|root,COG1572@2|Bacteria,2H888@201174|Actinobacteria	201174|Actinobacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_476952_6	479435.Kfla_3510	1.069e-45	183.0	COG1277@1|root,COG1277@2|Bacteria,2H46W@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WLSH2_k127_476952_3	479435.Kfla_3511	3.766e-84	290.0	COG1131@1|root,COG1131@2|Bacteria,2GK1W@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_476952_1	1057002.KB905370_gene3674	1.894e-313	990.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2TRWM@28211|Alphaproteobacteria,4BB6Z@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	cation efflux system protein (Heavy metal efflux pump)	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WLSH2_k127_476952_5	1128421.JAGA01000003_gene3596	2.267e-56	204.0	COG0745@1|root,COG0745@2|Bacteria,2NR2D@2323|unclassified Bacteria	2|Bacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_476952_17	272134.KB731324_gene4791	0.0002999	44.0	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
WLSH2_k127_476952_2	1499967.BAYZ01000060_gene6002	1.715e-173	569.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
WLSH2_k127_476952_11	926569.ANT_03120	1.685e-23	104.0	COG4448@1|root,COG4448@2|Bacteria	2|Bacteria	E	L-asparaginase II	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_II
WLSH2_k127_476952_12	313606.M23134_05603	2.274e-22	103.0	2E7WD@1|root,332B1@2|Bacteria,4P3PA@976|Bacteroidetes,47UUH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_476952_7	1163407.UU7_04622	3.707e-37	149.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1X8XV@135614|Xanthomonadales	135614|Xanthomonadales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
WLSH2_k127_4774627_11	1265507.KB899642_gene2657	0.000228	46.0	COG1716@1|root,COG1716@2|Bacteria,1RBAY@1224|Proteobacteria,1S7SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
WLSH2_k127_4774627_1	324925.Ppha_0758	6.883e-63	223.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH2_k127_4774627_6	1304865.JAGF01000001_gene3323	1.993e-12	73.0	28PN6@1|root,2ZCB1@2|Bacteria,2INN5@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
WLSH2_k127_4774627_0	240015.ACP_3313	3.255e-138	443.0	COG0190@1|root,COG0190@2|Bacteria,3Y2IN@57723|Acidobacteria,2JMQ0@204432|Acidobacteriia	204432|Acidobacteriia	F	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WLSH2_k127_4774627_7	227377.CBU_0774	3.17e-11	65.0	COG1983@1|root,COG1983@2|Bacteria,1NGIB@1224|Proteobacteria,1T7AM@1236|Gammaproteobacteria,1JF4Z@118969|Legionellales	118969|Legionellales	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
WLSH2_k127_4774627_5	485913.Krac_1097	2.11e-21	100.0	2BWWR@1|root,2ZG0F@2|Bacteria	2|Bacteria	S	pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
WLSH2_k127_4774627_4	410358.Mlab_1184	7.175e-28	126.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,2NAUF@224756|Methanomicrobia	224756|Methanomicrobia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_4774627_9	1121097.JCM15093_2424	7.173e-08	63.0	COG1266@1|root,COG1266@2|Bacteria,4NMMK@976|Bacteroidetes,2FP40@200643|Bacteroidia,4ANCM@815|Bacteroidaceae	976|Bacteroidetes	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_4774627_2	1382306.JNIM01000001_gene2336	5.115e-38	155.0	arCOG10178@1|root,2ZAAA@2|Bacteria	2|Bacteria	S	PFAM CAAX amino terminal protease family	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_4774627_3	489825.LYNGBM3L_16340	1.002e-37	145.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
WLSH2_k127_4784097_6	102129.Lepto7375DRAFT_7801	1.932e-89	306.0	COG3547@1|root,COG3547@2|Bacteria,1G077@1117|Cyanobacteria,1H97S@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
WLSH2_k127_4784097_7	635013.TherJR_1461	1.658e-79	280.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
WLSH2_k127_4784097_21	926569.ANT_17670	0.0001025	46.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH2_k127_4784097_2	880072.Desac_0095	1.109e-116	386.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
WLSH2_k127_4784097_0	926560.KE387023_gene1701	4.426e-200	663.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WLSH2_k127_4784097_17	1123073.KB899241_gene2834	1.996e-13	74.0	COG0596@1|root,COG0596@2|Bacteria,1QVBQ@1224|Proteobacteria,1T2BH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4784097_14	1121875.KB907548_gene1637	3.307e-22	112.0	COG0664@1|root,COG0664@2|Bacteria,4NRPE@976|Bacteroidetes	976|Bacteroidetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WLSH2_k127_4784097_5	1168034.FH5T_19015	7.462e-102	355.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4784097_1	926560.KE387023_gene3595	1.691e-121	419.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
WLSH2_k127_4784097_16	69014.TK2241	4.842e-17	90.0	COG0500@1|root,arCOG01790@2157|Archaea,2XWZ1@28890|Euryarchaeota,24335@183968|Thermococci	183968|Thermococci	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH2_k127_4784097_3	351627.Csac_1027	1.591e-109	367.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,42F31@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
WLSH2_k127_4784097_19	240016.ABIZ01000001_gene3022	1.131e-08	65.0	COG2162@1|root,COG2162@2|Bacteria	2|Bacteria	Q	arylamine N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_2
WLSH2_k127_4784097_15	1157634.KB912999_gene4684	4.179e-17	93.0	COG2813@1|root,COG2813@2|Bacteria,2I4JN@201174|Actinobacteria	201174|Actinobacteria	J	O-methyltransferase	-	-	2.1.1.304	ko:K21460	-	-	-	-	ko00000,ko01000	-	-	-	Dimerisation2,Methyltransf_2
WLSH2_k127_4784097_8	391037.Sare_0183	2.385e-57	208.0	COG1266@1|root,COG1266@2|Bacteria,2IGUR@201174|Actinobacteria,4DK0K@85008|Micromonosporales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_4784097_18	415426.Hbut_0037	5.863e-13	80.0	COG0535@1|root,arCOG00938@2157|Archaea,2XPPA@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM Radical SAM domain protein	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WLSH2_k127_4784097_9	926569.ANT_29500	7.027e-50	186.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_4784097_12	913325.N799_11035	5.97e-24	109.0	COG1622@1|root,COG2132@1|root,COG1622@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,1RXZF@1236|Gammaproteobacteria,1X9Y2@135614|Xanthomonadales	135614|Xanthomonadales	CQ	nitrite reductase	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
WLSH2_k127_4784097_20	1298858.AUEL01000026_gene3435	4.913e-06	56.0	2EK0M@1|root,33DR5@2|Bacteria,1NKNS@1224|Proteobacteria,2UNJZ@28211|Alphaproteobacteria,43P8N@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
WLSH2_k127_4784097_11	1499967.BAYZ01000115_gene2930	1.419e-24	109.0	COG1475@1|root,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
WLSH2_k127_4784097_13	1077972.ARGLB_008_00330	7.232e-23	108.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_4784097_10	485913.Krac_0393	1.514e-39	158.0	COG1266@1|root,COG1266@2|Bacteria,2G772@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_4784097_22	658655.HMPREF0988_03165	0.0008731	44.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,27PAH@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WLSH2_k127_4784097_4	1128421.JAGA01000003_gene3678	1.098e-107	377.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
WLSH2_k127_4802275_14	1172179.AUKV01000009_gene4532	9.158e-41	156.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
WLSH2_k127_4802275_2	688269.Theth_1455	3.458e-171	555.0	COG0449@1|root,COG0449@2|Bacteria,2GBY1@200918|Thermotogae	200918|Thermotogae	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
WLSH2_k127_4802275_12	373994.Riv7116_5263	2.764e-47	173.0	COG0346@1|root,COG0346@2|Bacteria,1GF52@1117|Cyanobacteria	1117|Cyanobacteria	E	Glyoxalase-like domain	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
WLSH2_k127_4802275_5	926569.ANT_29900	6.478e-131	429.0	COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi	200795|Chloroflexi	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
WLSH2_k127_4802275_6	1499967.BAYZ01000161_gene384	1.355e-102	341.0	COG1814@1|root,COG1814@2|Bacteria,2NP4E@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
WLSH2_k127_4802275_0	329726.AM1_2452	2.991e-263	861.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WLSH2_k127_4802275_15	287.DR97_4598	5.154e-27	126.0	COG1020@1|root,COG1020@2|Bacteria,1NBUQ@1224|Proteobacteria,1SEPG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
WLSH2_k127_4802275_3	357808.RoseRS_3935	3.555e-139	477.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2G7J8@200795|Chloroflexi,374RZ@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
WLSH2_k127_4802275_20	224915.bbp_322	1.608e-07	57.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,37DDB@32199|Buchnera	1236|Gammaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH2_k127_4802275_8	2340.JV46_23410	3.539e-75	272.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1T1II@1236|Gammaproteobacteria,1J8WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyltransferase,Aminotran_1_2,NAD_binding_4,PP-binding,Thioesterase
WLSH2_k127_4802275_16	395493.BegalDRAFT_1333	8.275e-27	115.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,1S98P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH2_k127_4802275_10	290315.Clim_1053	1.795e-58	210.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	chpE	-	-	ko:K06600,ko:K06895	-	-	-	-	ko00000,ko02000,ko02035	2.A.75.1,2.A.76	-	-	LysE
WLSH2_k127_4802275_7	1295642.H839_08913	1.44e-76	266.0	COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,4HFFF@91061|Bacilli	91061|Bacilli	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_4802275_11	324602.Caur_0597	2.97e-54	197.0	COG3467@1|root,COG3467@2|Bacteria,2G94U@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
WLSH2_k127_4802275_21	411469.EUBHAL_00708	1.303e-05	55.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,25WT5@186806|Eubacteriaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
WLSH2_k127_4802275_4	545693.BMQ_0847	5.297e-131	426.0	COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,1ZC9Q@1386|Bacillus	91061|Bacilli	H	homocysteine	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
WLSH2_k127_4802275_9	485913.Krac_5203	4.432e-62	221.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25
WLSH2_k127_4802275_13	1121015.N789_00635	2.083e-46	173.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,1SGRZ@1236|Gammaproteobacteria,1X6RX@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
WLSH2_k127_4802275_18	237368.SCABRO_00865	3.793e-16	83.0	COG1895@1|root,COG1895@2|Bacteria,2J4E4@203682|Planctomycetes	203682|Planctomycetes	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
WLSH2_k127_4802275_19	1499967.BAYZ01000076_gene789	6.318e-09	62.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07061	-	-	-	-	ko00000,ko02048	-	-	-	NTP_transf_2
WLSH2_k127_4802275_17	755178.Cyan10605_1187	5.651e-18	87.0	COG1708@1|root,COG1708@2|Bacteria,1G9J2@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH2_k127_4802275_1	926569.ANT_16800	1.143e-194	613.0	COG1003@1|root,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
WLSH2_k127_4814646_17	926569.ANT_14430	2.561e-50	180.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
WLSH2_k127_4814646_16	926550.CLDAP_12770	1.886e-51	192.0	COG0778@1|root,COG0778@2|Bacteria,2G693@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_4814646_23	797209.ZOD2009_16563	2.777e-30	124.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XXT7@28890|Euryarchaeota,23WEB@183963|Halobacteria	183963|Halobacteria	S	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
WLSH2_k127_4814646_24	521045.Kole_0517	5.799e-27	116.0	COG0221@1|root,COG0221@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
WLSH2_k127_4814646_11	926569.ANT_14410	1.262e-104	346.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM F420-dependent oxidoreductase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
WLSH2_k127_4814646_12	926569.ANT_14400	7.788e-86	289.0	COG2085@1|root,COG2085@2|Bacteria,2G7DD@200795|Chloroflexi	200795|Chloroflexi	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
WLSH2_k127_4814646_2	926569.ANT_14390	4.969e-178	571.0	COG0402@1|root,COG0402@2|Bacteria,2G7M9@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WLSH2_k127_4814646_7	926569.ANT_18420	7.961e-133	454.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DNA_alkylation,GUN4,HEAT_2,Mrr_cat,NACHT
WLSH2_k127_4814646_18	926569.ANT_18410	1.074e-47	179.0	COG1579@1|root,COG1579@2|Bacteria,2G775@200795|Chloroflexi	200795|Chloroflexi	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
WLSH2_k127_4814646_3	926569.ANT_12990	1.405e-163	528.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
WLSH2_k127_4814646_10	926569.ANT_04210	7.529e-110	365.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
WLSH2_k127_4814646_20	570967.JMLV01000010_gene1193	3.887e-44	169.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,2JPRF@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WLSH2_k127_4814646_31	700598.Niako_2084	1.096e-07	60.0	2AYX9@1|root,31R2Z@2|Bacteria,4NNS4@976|Bacteroidetes,1IXP4@117747|Sphingobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_4814646_5	485915.Dret_1447	9.471e-143	461.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,42Q5H@68525|delta/epsilon subdivisions,2WKW4@28221|Deltaproteobacteria,2M80H@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WLSH2_k127_4814646_21	926569.ANT_04220	2.803e-38	154.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Flavodoxin_2,UbiA
WLSH2_k127_4814646_4	926569.ANT_04230	1.204e-146	475.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi	200795|Chloroflexi	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WLSH2_k127_4814646_30	1173024.KI912148_gene2616	4.805e-12	78.0	COG1413@1|root,COG1413@2|Bacteria,1G6P1@1117|Cyanobacteria	1117|Cyanobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_PBS
WLSH2_k127_4814646_8	1519464.HY22_00065	1.885e-128	417.0	COG1171@1|root,COG1171@2|Bacteria	2|Bacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_4814646_13	558884.JRGM01000141_gene1800	2.39e-70	250.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,1Y4JE@135624|Aeromonadales	135624|Aeromonadales	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
WLSH2_k127_4814646_25	926569.ANT_11510	1.592e-19	94.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4814646_29	338966.Ppro_2695	2.848e-13	78.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,42RRN@68525|delta/epsilon subdivisions,2WNAY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4814646_27	926569.ANT_11510	1.691e-15	80.0	COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4814646_26	1123009.AUID01000008_gene835	3.234e-16	83.0	COG2261@1|root,COG2261@2|Bacteria,1VEUE@1239|Firmicutes,24RAN@186801|Clostridia	186801|Clostridia	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WLSH2_k127_4814646_14	1134413.ANNK01000001_gene2150	1.023e-65	232.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli,1ZAT8@1386|Bacillus	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	yycF	GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_4814646_15	868595.Desca_1433	1.133e-54	210.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,260UH@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K10681	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_4814646_22	1519464.HY22_12210	1.677e-32	138.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
WLSH2_k127_4814646_9	1121324.CLIT_4c01880	7.89e-115	383.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,25QZ5@186804|Peptostreptococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WLSH2_k127_4814646_6	518766.Rmar_1320	7.398e-140	458.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,1FIZQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WLSH2_k127_4814646_1	926550.CLDAP_40520	1.016e-189	602.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
WLSH2_k127_4814646_0	926569.ANT_04250	1.458e-280	876.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi	200795|Chloroflexi	K	PBP superfamily domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	HTH_3,MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
WLSH2_k127_4814646_28	543728.Vapar_1658	5.881e-14	76.0	COG0642@1|root,COG2199@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,4ADN0@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WLSH2_k127_4814646_19	926569.ANT_04260	5.503e-45	169.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH2_k127_488195_29	614083.AWQR01000011_gene2373	5.152e-44	167.0	2C6CV@1|root,33W8F@2|Bacteria,1RM05@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_488195_30	588581.Cpap_1123	2.152e-38	149.0	2F81H@1|root,340EZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_488195_17	1128421.JAGA01000003_gene3537	4.434e-89	299.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_488195_11	1128421.JAGA01000003_gene3536	1.049e-113	381.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_488195_26	1128421.JAGA01000003_gene3074	3.625e-54	201.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WLSH2_k127_488195_32	565045.NOR51B_339	0.0002543	44.0	COG1028@1|root,COG1028@2|Bacteria	565045.NOR51B_339|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_488195_14	926569.ANT_04070	3.5e-101	335.0	COG1349@1|root,COG1349@2|Bacteria,2G6FT@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
WLSH2_k127_488195_13	1499967.BAYZ01000177_gene5702	1.88e-106	360.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
WLSH2_k127_488195_20	1499967.BAYZ01000177_gene5704	5.25e-85	291.0	COG1175@1|root,COG1175@2|Bacteria,2NPAH@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WLSH2_k127_488195_21	1499967.BAYZ01000177_gene5703	1.888e-80	277.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH2_k127_488195_2	926569.ANT_04060	1.34e-172	548.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WLSH2_k127_488195_3	1267535.KB906767_gene4121	2.532e-159	525.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
WLSH2_k127_488195_25	926569.ANT_12210	3.576e-55	207.0	COG1653@1|root,COG1653@2|Bacteria,2G7EJ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
WLSH2_k127_488195_15	926569.ANT_04050	1.182e-99	336.0	COG2222@1|root,COG2222@2|Bacteria,2G66K@200795|Chloroflexi	200795|Chloroflexi	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
WLSH2_k127_488195_6	926550.CLDAP_23100	1.445e-129	428.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_488195_12	926550.CLDAP_23090	5.343e-112	372.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
WLSH2_k127_488195_16	926550.CLDAP_23080	3.424e-99	331.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH2_k127_488195_22	926550.CLDAP_23070	2.636e-79	273.0	COG1486@1|root,COG1486@2|Bacteria	2|Bacteria	G	melibiose metabolic process	-	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WLSH2_k127_488195_18	1254432.SCE1572_50660	6.62e-88	313.0	2DBEW@1|root,2Z8UY@2|Bacteria,1QZEI@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
WLSH2_k127_488195_31	42256.RradSPS_1227	3.839e-33	146.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
WLSH2_k127_488195_4	1163408.UU9_00170	1.349e-141	463.0	2DUQS@1|root,33RT2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_488195_0	926569.ANT_04010	1.132e-258	800.0	COG1486@1|root,COG1486@2|Bacteria,2G858@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
WLSH2_k127_488195_8	926569.ANT_03990	1.156e-119	391.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi	200795|Chloroflexi	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	lacD	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
WLSH2_k127_488195_9	926569.ANT_03980	3.273e-119	390.0	COG0524@1|root,COG0524@2|Bacteria,2G6W1@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WLSH2_k127_488195_7	1397284.AYMN01000087_gene1752	1.665e-126	417.0	COG4573@1|root,COG4573@2|Bacteria,1MW3Q@1224|Proteobacteria,1RQAU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of	-	-	-	ko:K02775,ko:K16371	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R01069,R05570	RC00017,RC00438,RC00439,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5.1	-	-	Tagatose_6_P_K
WLSH2_k127_488195_27	1499967.BAYZ01000179_gene4623	4.625e-54	200.0	29FVD@1|root,302T2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_488195_24	926569.ANT_18530	7.158e-56	200.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi	200795|Chloroflexi	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WLSH2_k127_488195_19	926550.CLDAP_06250	2.836e-85	298.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MFS_1
WLSH2_k127_488195_23	1121928.AUHE01000004_gene2508	1.182e-74	266.0	COG5621@1|root,COG5621@2|Bacteria,2GNHM@201174|Actinobacteria,4GAD3@85026|Gordoniaceae	201174|Actinobacteria	S	CrtC N-terminal lipocalin domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC
WLSH2_k127_488195_10	439235.Dalk_4954	6.963e-116	386.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42S94@68525|delta/epsilon subdivisions,2WNCW@28221|Deltaproteobacteria,2MNBQ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
WLSH2_k127_488195_5	439235.Dalk_4953	5.223e-133	463.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
WLSH2_k127_488195_1	439235.Dalk_4952	3.377e-178	597.0	COG0277@1|root,COG0277@2|Bacteria,1NUIU@1224|Proteobacteria	1224|Proteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
WLSH2_k127_488195_28	1120973.AQXL01000102_gene2648	6.241e-54	216.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,4HADH@91061|Bacilli,2798T@186823|Alicyclobacillaceae	91061|Bacilli	K	Bacterial transcriptional activator domain	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,BTAD,TPR_12,TPR_8
WLSH2_k127_4896134_19	933262.AXAM01000113_gene2121	6.878e-13	70.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,42TEG@68525|delta/epsilon subdivisions,2WPXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_4896134_17	1196031.ALEG01000011_gene5264	3.306e-14	86.0	COG3103@1|root,COG4990@1|root,COG3103@2|Bacteria,COG4990@2|Bacteria,COG4991@2|Bacteria,1V3XE@1239|Firmicutes,4HZA4@91061|Bacilli,1ZEKK@1386|Bacillus	91061|Bacilli	T	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,SH3_3,SLH
WLSH2_k127_4896134_6	926550.CLDAP_13280	4.072e-95	327.0	COG3534@1|root,COG3534@2|Bacteria,2G8SV@200795|Chloroflexi	200795|Chloroflexi	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4896134_11	1122176.KB903534_gene2189	1.959e-44	166.0	COG0454@1|root,COG0454@2|Bacteria,4NPMJ@976|Bacteroidetes,1IZ74@117747|Sphingobacteriia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_4896134_15	1211813.CAPH01000006_gene1398	8.849e-19	89.0	COG2388@1|root,COG2388@2|Bacteria,4NVD1@976|Bacteroidetes,2FU4P@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG21176 non supervised orthologous group	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
WLSH2_k127_4896134_10	309799.DICTH_0695	6.559e-52	197.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH2_k127_4896134_1	926569.ANT_25010	1.068e-240	749.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
WLSH2_k127_4896134_0	926569.ANT_24980	3.096e-310	971.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WLSH2_k127_4896134_5	552811.Dehly_1236	6.201e-100	339.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi,34CPK@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WLSH2_k127_4896134_12	479432.Sros_3733	3.764e-31	127.0	COG1051@1|root,COG1051@2|Bacteria,2IIJJ@201174|Actinobacteria,4EJRA@85012|Streptosporangiales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_4896134_8	1089553.Tph_c26220	2.104e-82	284.0	COG5322@1|root,COG5322@2|Bacteria,1TQ2E@1239|Firmicutes,24A1Y@186801|Clostridia,42EUN@68295|Thermoanaerobacterales	186801|Clostridia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4896134_3	926569.ANT_00200	3.891e-134	439.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WLSH2_k127_4896134_13	926569.ANT_01320	7.363e-31	126.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi	200795|Chloroflexi	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
WLSH2_k127_4896134_9	224325.AF_0130	1.393e-67	243.0	COG0123@1|root,arCOG00324@2157|Archaea,2XT0B@28890|Euryarchaeota,246V5@183980|Archaeoglobi	183980|Archaeoglobi	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WLSH2_k127_4896134_18	1313421.JHBV01000016_gene5604	2.144e-13	81.0	2DHAX@1|root,32U8Z@2|Bacteria	2|Bacteria	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
WLSH2_k127_4896134_4	926569.ANT_30250	7.381e-128	422.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_4896134_2	1116472.MGMO_94c00490	6.625e-163	524.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RRAS@1236|Gammaproteobacteria,1XEII@135618|Methylococcales	135618|Methylococcales	S	flavoprotein, PP_4765 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WLSH2_k127_4896134_7	1499967.BAYZ01000026_gene1636	1.647e-84	288.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
WLSH2_k127_4896134_22	1500257.JQNM01000008_gene1235	7.649e-09	66.0	COG2267@1|root,COG2267@2|Bacteria,1RG43@1224|Proteobacteria,2U6MB@28211|Alphaproteobacteria,4BD03@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WLSH2_k127_4960395_43	357808.RoseRS_3625	5.621e-11	65.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZW@200795|Chloroflexi,37567@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WLSH2_k127_4960395_10	926569.ANT_20460	1.395e-158	516.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi	200795|Chloroflexi	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
WLSH2_k127_4960395_13	926569.ANT_20590	5.267e-150	482.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
WLSH2_k127_4960395_17	926569.ANT_14480	6.364e-106	351.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi	200795|Chloroflexi	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
WLSH2_k127_4960395_20	1303518.CCALI_02921	5.039e-93	321.0	COG0517@1|root,COG1227@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
WLSH2_k127_4960395_16	706587.Desti_5093	2.643e-109	394.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_4960395_0	926569.ANT_14470	0.0	1487.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G5NF@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	xdh	-	-	ko:K12528	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
WLSH2_k127_4960395_18	1121403.AUCV01000065_gene4170	5.64e-97	337.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2X5IZ@28221|Deltaproteobacteria,2MPF3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
WLSH2_k127_4960395_19	326427.Cagg_3343	7.659e-96	339.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,2GAC9@200795|Chloroflexi,376M5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WLSH2_k127_4960395_42	877414.ATWA01000010_gene2311	5.483e-16	90.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
WLSH2_k127_4960395_11	926569.ANT_23780	2.769e-156	505.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi	200795|Chloroflexi	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
WLSH2_k127_4960395_4	886293.Sinac_6978	4.067e-210	671.0	COG0488@1|root,COG0488@2|Bacteria,2IX59@203682|Planctomycetes	203682|Planctomycetes	S	ABC transporter	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH2_k127_4960395_48	1430440.MGMSRv2_1708	6.899e-05	55.0	2EQWR@1|root,33IGI@2|Bacteria,1NNN3@1224|Proteobacteria,2UJW6@28211|Alphaproteobacteria,2JVIF@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4960395_24	1128421.JAGA01000003_gene3228	1.403e-85	294.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_4960395_31	926569.ANT_14460	7.554e-51	189.0	COG1319@1|root,COG1319@2|Bacteria,2G9PS@200795|Chloroflexi	200795|Chloroflexi	C	FAD binding domain in molybdopterin dehydrogenase	-	-	1.2.5.3	ko:K03519,ko:K12529	ko00450,map00450	-	R07229,R11168	RC02420,RC02800	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
WLSH2_k127_4960395_27	926569.ANT_25970	6.042e-63	220.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi	200795|Chloroflexi	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WLSH2_k127_4960395_33	1499967.BAYZ01000095_gene4130	4.648e-46	174.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	pfs	-	3.2.2.1,3.2.2.9,4.1.99.14	ko:K01239,ko:K01243,ko:K03716	ko00230,ko00270,ko00760,ko01100,ko01230,map00230,map00270,map00760,map01100,map01230	M00034,M00609	R00194,R01245,R01273,R01401,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WLSH2_k127_4960395_35	1174528.JH992898_gene4351	1.606e-35	140.0	COG0454@1|root,COG0456@2|Bacteria,1G7ME@1117|Cyanobacteria,1JMPE@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
WLSH2_k127_4960395_14	1191523.MROS_1373	2.075e-147	478.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_4960395_3	1191523.MROS_1372	1.087e-234	737.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WLSH2_k127_4960395_47	439235.Dalk_2288	2.294e-05	51.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,2MPW6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
WLSH2_k127_4960395_45	1499967.BAYZ01000095_gene4165	2.422e-10	65.0	COG1895@1|root,COG1895@2|Bacteria,2NRPS@2323|unclassified Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
WLSH2_k127_4960395_44	555779.Dthio_PD2829	6.846e-11	66.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07061	-	-	-	-	ko00000,ko02048	-	-	-	NTP_transf_2
WLSH2_k127_4960395_8	926550.CLDAP_27570	4.204e-170	543.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_4960395_41	1125863.JAFN01000001_gene2795	4.095e-17	89.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions,2WRHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S domain	pcmE	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
WLSH2_k127_4960395_32	765420.OSCT_2993	1.102e-48	195.0	COG1290@1|root,COG1290@2|Bacteria,2G7XY@200795|Chloroflexi,377D3@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
WLSH2_k127_4960395_49	381666.H16_A3571	7.886e-05	55.0	COG3258@1|root,COG4654@1|root,COG3258@2|Bacteria,COG4654@2|Bacteria,1QTYW@1224|Proteobacteria,2VIQV@28216|Betaproteobacteria,1K6FN@119060|Burkholderiaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
WLSH2_k127_4960395_30	335541.Swol_1996	5.81e-51	208.0	COG0664@1|root,COG1413@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	HEAT_2,HTH_Crp_2,cNMP_binding
WLSH2_k127_4960395_28	926569.ANT_30890	2.891e-57	207.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
WLSH2_k127_4960395_9	864051.BurJ1DRAFT_2687	3.966e-168	544.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,2VWMP@28216|Betaproteobacteria,1KNZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WLSH2_k127_4960395_23	864051.BurJ1DRAFT_2686	1.949e-87	292.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,2VXAQ@28216|Betaproteobacteria,1KP4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WLSH2_k127_4960395_1	864051.BurJ1DRAFT_2685	0.0	1119.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WLSH2_k127_4960395_2	864051.BurJ1DRAFT_2684	9.512e-243	756.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria,1KN5Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
WLSH2_k127_4960395_40	926569.ANT_27650	3.426e-26	112.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WLSH2_k127_4960395_26	926569.ANT_15430	5.702e-74	254.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
WLSH2_k127_4960395_37	926569.ANT_18000	4.058e-33	131.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
WLSH2_k127_4960395_25	926569.ANT_17990	9.287e-78	265.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
WLSH2_k127_4960395_15	926569.ANT_17980	4.913e-142	453.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ABC transporter related	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WLSH2_k127_4960395_6	765420.OSCT_1489	6.946e-187	628.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi,374ZV@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WLSH2_k127_4960395_7	926569.ANT_17960	2.905e-181	577.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
WLSH2_k127_4960395_5	926569.ANT_17940	7.08e-192	605.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
WLSH2_k127_4960395_29	926569.ANT_17930	6.853e-56	197.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WLSH2_k127_4960395_36	926569.ANT_17920	1.884e-34	135.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
WLSH2_k127_4960395_34	926550.CLDAP_26800	1.235e-39	154.0	2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_4960395_21	926569.ANT_17910	2.419e-92	307.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	yaiS	-	-	-	-	-	-	-	-	-	-	-	PIG-L,Response_reg
WLSH2_k127_4960395_22	926569.ANT_17900	5.37e-88	298.0	COG0500@1|root,COG2226@2|Bacteria,2G78Q@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_4960395_12	926569.ANT_17720	6.082e-156	502.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WLSH2_k127_4960395_39	406124.ACPC01000018_gene2598	7.807e-28	118.0	COG0454@1|root,COG0456@2|Bacteria,1V1NC@1239|Firmicutes,4ISA1@91061|Bacilli,1ZIFJ@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_3
WLSH2_k127_4973523_3	456442.Mboo_1810	1.7e-52	191.0	arCOG06712@1|root,arCOG07605@1|root,arCOG06712@2157|Archaea,arCOG07605@2157|Archaea,2Y7KG@28890|Euryarchaeota	28890|Euryarchaeota	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
WLSH2_k127_4973523_1	1120950.KB892749_gene3367	5.728e-83	289.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DN4V@85009|Propionibacteriales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	ugpC	-	3.6.3.20	ko:K05816	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1.3	-	-	ABC_tran,TOBE_2
WLSH2_k127_4973523_2	306281.AJLK01000102_gene3405	1.586e-66	231.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4973523_7	485913.Krac_3918	5.389e-23	100.0	COG3385@1|root,COG3385@2|Bacteria,2G80K@200795|Chloroflexi	200795|Chloroflexi	L	sptr a7nhu5	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_4973523_9	1283300.ATXB01000001_gene2387	9.166e-19	86.0	COG3385@1|root,COG3385@2|Bacteria,1PHKQ@1224|Proteobacteria,1SIFZ@1236|Gammaproteobacteria	1224|Proteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_4973523_0	1283300.ATXB01000001_gene2414	1.021e-109	362.0	COG3385@1|root,COG3385@2|Bacteria,1PHKQ@1224|Proteobacteria,1SIFZ@1236|Gammaproteobacteria	1224|Proteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_4973523_4	1123248.KB893316_gene4667	2.374e-49	178.0	COG5646@1|root,COG5646@2|Bacteria,4NSDH@976|Bacteroidetes,1ITAW@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WLSH2_k127_4973523_5	1265505.ATUG01000001_gene4448	4.83e-44	165.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_4973523_8	338963.Pcar_0529	8.485e-21	97.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_4973523_10	1265505.ATUG01000002_gene1624	1.136e-06	55.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,42N7X@68525|delta/epsilon subdivisions,2WMM9@28221|Deltaproteobacteria,2MMU3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_4973523_6	666685.R2APBS1_2498	5.73e-30	124.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria,1X8XV@135614|Xanthomonadales	135614|Xanthomonadales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
WLSH2_k127_4984363_8	345341.KUTG_04850	4.809e-36	155.0	COG5421@1|root,COG5421@2|Bacteria,2IEYR@201174|Actinobacteria	201174|Actinobacteria	L	Domain of unknown function (DUF4277)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4277
WLSH2_k127_4984363_3	351160.RCIX1164	8.093e-71	252.0	COG0535@1|root,arCOG00938@2157|Archaea	2157|Archaea	P	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
WLSH2_k127_4984363_13	504472.Slin_0852	6.783e-15	81.0	arCOG09454@1|root,30G4A@2|Bacteria,4NPSB@976|Bacteroidetes,47Q9D@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4984363_12	1296415.JACC01000038_gene1906	1.815e-15	80.0	2EMYX@1|root,33FM2@2|Bacteria,4NY90@976|Bacteroidetes,1IBIV@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4984363_9	3218.PP1S9_169V6.1	4.971e-33	133.0	28NEG@1|root,2S3TG@2759|Eukaryota,37W4G@33090|Viridiplantae,3GXEK@35493|Streptophyta	35493|Streptophyta	S	Staygreen protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647	4.99.1.10	ko:K22013	ko00860,ko01110,map00860,map01110	-	R08584,R09033	RC01012	ko00000,ko00001,ko01000	-	-	-	Staygreen
WLSH2_k127_4984363_14	882083.SacmaDRAFT_1477	1.381e-09	71.0	COG3568@1|root,COG3568@2|Bacteria,2HEP6@201174|Actinobacteria,4E819@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WLSH2_k127_4984363_7	926569.ANT_05870	5.526e-50	184.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	pilL	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K02487,ko:K03407,ko:K03413,ko:K06596,ko:K11526,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507,M00508,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
WLSH2_k127_4984363_11	317655.Sala_0696	6.994e-17	83.0	COG2944@1|root,COG2944@2|Bacteria,1PKMK@1224|Proteobacteria,2V744@28211|Alphaproteobacteria,2KBJJ@204457|Sphingomonadales	204457|Sphingomonadales	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4984363_10	393305.YE2901	1.417e-26	109.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,1SCBE@1236|Gammaproteobacteria,41GFR@629|Yersinia	1236|Gammaproteobacteria	S	DNA-binding protein VF530	-	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	VF530
WLSH2_k127_4984363_2	867845.KI911784_gene1656	4.992e-106	351.0	COG3868@1|root,COG3868@2|Bacteria,2G7U5@200795|Chloroflexi,3775X@32061|Chloroflexia	32061|Chloroflexia	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
WLSH2_k127_4984363_1	562970.Btus_1445	4.94e-115	384.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF_1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH2_k127_4984363_5	926569.ANT_05870	1.825e-55	200.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	pilL	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K02487,ko:K03407,ko:K03413,ko:K06596,ko:K11526,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507,M00508,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
WLSH2_k127_4984363_6	926550.CLDAP_28610	2.256e-50	190.0	COG0566@1|root,COG0566@2|Bacteria,2G8WM@200795|Chloroflexi	200795|Chloroflexi	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
WLSH2_k127_4984363_0	1499967.BAYZ01000052_gene4665	1.999e-169	579.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_7,TPR_8
WLSH2_k127_4984363_4	926569.ANT_22260	1.075e-62	220.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH2_k127_4990326_2	357808.RoseRS_3212	1.234e-54	196.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
WLSH2_k127_4990326_1	357808.RoseRS_3212	1.566e-95	326.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
WLSH2_k127_4990326_4	926569.ANT_11780	4.424e-41	172.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WLSH2_k127_4990326_5	1121895.Q765_12580	2.621e-11	68.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,2NT3G@237|Flavobacterium	976|Bacteroidetes	T	Chemotaxis protein CheY	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH2_k127_4990326_3	926569.ANT_11780	2.314e-47	193.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WLSH2_k127_4990326_0	484770.UFO1_1183	2.366e-119	408.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_5006307_24	1385935.N836_14320	1.56e-29	124.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_8,Roc
WLSH2_k127_5006307_25	317936.Nos7107_1413	1.987e-28	115.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	COR,LRR_1,LRR_4,LRR_8,LRR_9,Roc
WLSH2_k127_5006307_33	1385935.N836_09535	1.297e-14	82.0	COG1100@1|root,COG1262@1|root,COG1100@2|Bacteria,COG1262@2|Bacteria,1GHFW@1117|Cyanobacteria,1HF0J@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	COR,Roc,TIR_2
WLSH2_k127_5006307_7	926569.ANT_20510	3.761e-137	445.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
WLSH2_k127_5006307_27	1408254.T458_16740	3.795e-22	101.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,26YZG@186822|Paenibacillaceae	91061|Bacilli	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH2_k127_5006307_28	926550.CLDAP_22170	2.392e-21	103.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi	200795|Chloroflexi	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH2_k127_5006307_4	926569.ANT_20570	9.868e-154	488.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi	200795|Chloroflexi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
WLSH2_k127_5006307_1	926569.ANT_20580	3.019e-177	561.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
WLSH2_k127_5006307_29	1499967.BAYZ01000118_gene3301	3.531e-20	94.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	lsrG	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
WLSH2_k127_5006307_2	251229.Chro_2922	2.005e-172	550.0	28IMC@1|root,2Z8MV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5006307_14	370438.PTH_0220	5.065e-87	296.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
WLSH2_k127_5006307_3	316274.Haur_3626	1.362e-162	531.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,377YK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_5006307_5	926569.ANT_29680	2.488e-149	492.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_5006307_40	269799.Gmet_3274	0.0005356	50.0	COG1413@1|root,COG1413@2|Bacteria,1Q4ZD@1224|Proteobacteria,43076@68525|delta/epsilon subdivisions,2WVBJ@28221|Deltaproteobacteria,43UWA@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
WLSH2_k127_5006307_30	797303.Natpe_3980	8.943e-20	94.0	COG1569@1|root,arCOG02120@2157|Archaea,2XZ4S@28890|Euryarchaeota,23X68@183963|Halobacteria	183963|Halobacteria	V	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WLSH2_k127_5006307_31	667014.Thein_1962	9.972e-18	85.0	arCOG07672@1|root,32Z5Y@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
WLSH2_k127_5006307_35	522306.CAP2UW1_0533	6.086e-10	64.0	2DNZI@1|root,32ZX6@2|Bacteria,1NKC7@1224|Proteobacteria,2W4U4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM YgiT-type zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5006307_0	926569.ANT_14840	3.161e-257	808.0	COG2414@1|root,COG2414@2|Bacteria	2|Bacteria	C	aldehyde ferredoxin oxidoreductase activity	-	-	1.2.7.5,1.2.7.6	ko:K03738,ko:K11389	ko00010,ko00030,ko01100,ko01120,ko01200,ko01230,map00010,map00030,map01100,map01120,map01200,map01230	M00001,M00002,M00309	R07159,R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_5006307_36	667014.Thein_1962	9.158e-10	64.0	arCOG07672@1|root,32Z5Y@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
WLSH2_k127_5006307_34	522306.CAP2UW1_0533	3.476e-13	71.0	2DNZI@1|root,32ZX6@2|Bacteria,1NKC7@1224|Proteobacteria,2W4U4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM YgiT-type zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5006307_22	649638.Trad_0409	4.868e-48	178.0	COG1574@1|root,COG1574@2|Bacteria,1WINV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WLSH2_k127_5006307_16	1382356.JQMP01000004_gene492	2.392e-85	298.0	COG1506@1|root,COG1506@2|Bacteria,2G8QF@200795|Chloroflexi,27YT1@189775|Thermomicrobia	189775|Thermomicrobia	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
WLSH2_k127_5006307_8	1265505.ATUG01000001_gene4318	5.037e-135	445.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42Q8R@68525|delta/epsilon subdivisions,2WMDK@28221|Deltaproteobacteria,2MJEG@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_5006307_20	485913.Krac_10314	9.73e-60	220.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
WLSH2_k127_5006307_13	1304874.JAFY01000002_gene136	4.379e-87	308.0	COG0747@1|root,COG0747@2|Bacteria,3TC9K@508458|Synergistetes	508458|Synergistetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
WLSH2_k127_5006307_17	1304874.JAFY01000002_gene135	5.062e-81	281.0	COG0601@1|root,COG0601@2|Bacteria,3TAG1@508458|Synergistetes	508458|Synergistetes	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_5006307_19	1499967.BAYZ01000132_gene306	7.175e-72	266.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WLSH2_k127_5006307_15	292459.STH2824	4.683e-86	308.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WLSH2_k127_5006307_12	439481.Aboo_0845	2.157e-106	354.0	COG4608@1|root,arCOG00184@2157|Archaea,2Y5BH@28890|Euryarchaeota,3F31T@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	TIGRFAM oligopeptide dipeptide ABC transporter	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	iAF692.Mbar_A0472	ABC_tran,oligo_HPY
WLSH2_k127_5006307_18	1128421.JAGA01000002_gene693	7.293e-75	259.0	COG0566@1|root,COG0566@2|Bacteria,2NR96@2323|unclassified Bacteria	2|Bacteria	J	SpoU rRNA Methylase family	spoU	-	2.1.1.185,2.1.1.208	ko:K03218,ko:K03437,ko:K21514	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WLSH2_k127_5006307_11	604331.AUHY01000023_gene1638	3.309e-111	373.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_5006307_39	1121381.JNIV01000047_gene3228	1.375e-06	61.0	COG0500@1|root,COG2226@2|Bacteria,1WJ5U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_5006307_10	65393.PCC7424_3245	9.32e-116	410.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
WLSH2_k127_5006307_32	114615.BRADO2181	8.289e-15	89.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Peptidase_C14,Pkinase,WD40
WLSH2_k127_5006307_38	926569.ANT_29010	8.645e-09	61.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH2_k127_5006307_6	1499967.BAYZ01000159_gene536	2.536e-149	475.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	-	-	1.13.11.8	ko:K04100	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA,LigB
WLSH2_k127_5006307_37	102125.Xen7305DRAFT_00045250	4.814e-09	60.0	2BMES@1|root,32FZB@2|Bacteria,1GP7A@1117|Cyanobacteria,3VN36@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5006307_9	1120985.AUMI01000011_gene203	6.322e-125	415.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,4H2E3@909932|Negativicutes	909932|Negativicutes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
WLSH2_k127_5006307_26	1121403.AUCV01000013_gene3999	1.085e-25	110.0	2DYI2@1|root,349W0@2|Bacteria,1NZTD@1224|Proteobacteria,431EW@68525|delta/epsilon subdivisions,2WWNI@28221|Deltaproteobacteria,2MNU2@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5006307_23	1232437.KL662015_gene1264	9.234e-44	163.0	2C56A@1|root,32EMF@2|Bacteria,1NV56@1224|Proteobacteria,42ZEW@68525|delta/epsilon subdivisions,2WV0I@28221|Deltaproteobacteria,2MNCA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5006307_21	765914.ThisiDRAFT_2006	8.623e-53	190.0	COG3293@1|root,COG3293@2|Bacteria,1PVIT@1224|Proteobacteria,1SZ29@1236|Gammaproteobacteria,1X2IZ@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4096
WLSH2_k127_5009237_7	926569.ANT_25090	3.764e-79	278.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5009237_6	926569.ANT_00310	1.359e-94	328.0	COG0651@1|root,COG0651@2|Bacteria,2G9I2@200795|Chloroflexi	200795|Chloroflexi	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
WLSH2_k127_5009237_14	926569.ANT_23510	2.344e-54	210.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
WLSH2_k127_5009237_11	926569.ANT_14000	1.001e-64	225.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
WLSH2_k127_5009237_2	383372.Rcas_2438	7.568e-137	445.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia	32061|Chloroflexia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_5009237_3	926569.ANT_11200	2.187e-119	405.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
WLSH2_k127_5009237_10	313612.L8106_13405	2.738e-66	232.0	COG1878@1|root,COG1878@2|Bacteria,1G60Q@1117|Cyanobacteria,1HHEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
WLSH2_k127_5009237_12	485913.Krac_11359	6.549e-63	224.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_5009237_13	324602.Caur_0875	2.164e-60	226.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_5009237_17	926569.ANT_16040	2.46e-36	140.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WLSH2_k127_5009237_19	926569.ANT_16030	1.076e-23	102.0	COG1837@1|root,COG1837@2|Bacteria,2G7DU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
WLSH2_k127_5009237_15	926569.ANT_16020	3.233e-47	177.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi	200795|Chloroflexi	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WLSH2_k127_5009237_5	926569.ANT_16010	1.356e-106	354.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
WLSH2_k127_5009237_21	1128421.JAGA01000003_gene3142	0.0004132	43.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
WLSH2_k127_5009237_4	926569.ANT_16000	1.918e-112	373.0	COG0836@1|root,COG0836@2|Bacteria,2G5WW@200795|Chloroflexi	200795|Chloroflexi	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
WLSH2_k127_5009237_0	926569.ANT_15990	0.0	1113.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WLSH2_k127_5009237_8	926569.ANT_15980	2.353e-70	251.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5009237_16	926569.ANT_15970	4.272e-45	168.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WLSH2_k127_5009237_1	926569.ANT_15960	2.435e-179	569.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
WLSH2_k127_5009237_18	2074.JNYD01000022_gene1507	3.916e-35	140.0	COG1403@1|root,COG1403@2|Bacteria,2GYWG@201174|Actinobacteria	201174|Actinobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_3
WLSH2_k127_5017956_8	485913.Krac_8363	1.568e-08	56.0	COG1662@1|root,COG3677@1|root,COG1662@2|Bacteria,COG3677@2|Bacteria,2G9MB@200795|Chloroflexi	200795|Chloroflexi	L	Putative ATPase subunit of terminase (gpP-like)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23
WLSH2_k127_5017956_0	1341181.FLJC2902T_31020	1.043e-119	396.0	arCOG10456@1|root,2ZA6T@2|Bacteria,4NGZ2@976|Bacteroidetes,1HXIA@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5017956_3	448385.sce2707	5.524e-51	186.0	2E8ZQ@1|root,33397@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5017956_4	269797.Mbar_A0316	8.346e-48	178.0	arCOG05130@1|root,arCOG05130@2157|Archaea,2XZ27@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5017956_5	118168.MC7420_3443	4.868e-30	126.0	COG0778@1|root,COG0778@2|Bacteria,1G5XK@1117|Cyanobacteria,1HFCI@1150|Oscillatoriales	1117|Cyanobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_5017956_6	926550.CLDAP_21040	2.65e-16	83.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Biotin_lipoyl_2,Response_reg
WLSH2_k127_5017956_7	1294142.CINTURNW_3812	3.162e-13	79.0	2EHEG@1|root,33B6E@2|Bacteria,1VUPE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_5017956_1	926550.CLDAP_21020	9.287e-78	265.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_5017956_2	926550.CLDAP_21010	1.31e-68	252.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WLSH2_k127_5017956_9	634956.Geoth_3336	3.115e-05	53.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4I44Y@91061|Bacilli,1WH3R@129337|Geobacillus	91061|Bacilli	L	Recombinase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_5046915_1	1123508.JH636439_gene1132	7.644e-70	247.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
WLSH2_k127_5046915_0	926569.ANT_14870	1.289e-212	670.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WLSH2_k127_5051351_3	485913.Krac_10694	5.081e-16	83.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,rve,rve_3
WLSH2_k127_5051351_1	1489678.RDMS_10495	8.287e-53	205.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	nsr	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41
WLSH2_k127_5051351_0	485913.Krac_6032	3.144e-105	370.0	COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
WLSH2_k127_5051351_2	1382356.JQMP01000003_gene2032	6.083e-24	107.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi,27XVP@189775|Thermomicrobia	200795|Chloroflexi	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_5130560_36	595537.Varpa_1467	1.42e-18	86.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,2VVJM@28216|Betaproteobacteria,4AEUN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
WLSH2_k127_5130560_7	926569.ANT_02540	1.021e-98	333.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WLSH2_k127_5130560_5	926569.ANT_02800	7.174e-112	368.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
WLSH2_k127_5130560_1	926569.ANT_02790	6.222e-194	629.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
WLSH2_k127_5130560_18	926569.ANT_02780	9.092e-73	252.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WLSH2_k127_5130560_17	926569.ANT_25520	2.829e-81	274.0	COG0503@1|root,COG0503@2|Bacteria,2G71F@200795|Chloroflexi	200795|Chloroflexi	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WLSH2_k127_5130560_37	1122919.KB905566_gene2730	5.211e-15	80.0	COG0537@1|root,COG0537@2|Bacteria,1V9QX@1239|Firmicutes,4HJD9@91061|Bacilli,26Y6U@186822|Paenibacillaceae	91061|Bacilli	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WLSH2_k127_5130560_21	1499967.BAYZ01000110_gene3008	4.703e-58	217.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,rve,rve_3
WLSH2_k127_5130560_2	1121351.AUAP01000001_gene600	3.191e-175	565.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KPJ8@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
WLSH2_k127_5130560_29	926569.ANT_25500	9.071e-39	158.0	2DFV5@1|root,2ZT9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5130560_9	926569.ANT_29560	4.31e-98	344.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	CP_0034	-	-	-	-	-	-	-	-	-	-	-	BON,FHA,FTSW_RODA_SPOVE,Yop-YscD_cpl
WLSH2_k127_5130560_19	926569.ANT_29550	9.558e-72	256.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
WLSH2_k127_5130560_28	382464.ABSI01000011_gene2976	5.771e-39	149.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_5130560_8	926569.ANT_30070	1.836e-98	326.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WLSH2_k127_5130560_24	926569.ANT_11900	1.143e-51	196.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi	200795|Chloroflexi	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
WLSH2_k127_5130560_16	926569.ANT_11910	2.868e-85	289.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WLSH2_k127_5130560_3	926569.ANT_11930	8.264e-147	476.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WLSH2_k127_5130560_27	326427.Cagg_2344	2.627e-43	169.0	COG1357@1|root,COG1357@2|Bacteria,2G8U9@200795|Chloroflexi,377VZ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
WLSH2_k127_5130560_25	1191523.MROS_1674	6.243e-51	185.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WLSH2_k127_5130560_11	926550.CLDAP_37970	2.58e-95	317.0	28Q3B@1|root,2ZCKZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5130560_14	118161.KB235922_gene2311	1.225e-92	320.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WLSH2_k127_5130560_6	246197.MXAN_0891	4.74e-99	335.0	COG2382@1|root,COG2382@2|Bacteria,1MXJN@1224|Proteobacteria,43BHV@68525|delta/epsilon subdivisions,2X6WB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
WLSH2_k127_5130560_20	321327.CYA_2243	8.282e-59	210.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1H1NJ@1129|Synechococcus	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
WLSH2_k127_5130560_12	1173026.Glo7428_2034	4.187e-95	323.0	COG3268@1|root,COG3268@2|Bacteria,1G3XG@1117|Cyanobacteria	1117|Cyanobacteria	S	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
WLSH2_k127_5130560_30	1122221.JHVI01000014_gene1365	1.795e-37	146.0	COG0454@1|root,COG0456@2|Bacteria,1WK4D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	FR47-like protein	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WLSH2_k127_5130560_22	926567.TheveDRAFT_1630	5.368e-58	206.0	COG1528@1|root,COG1528@2|Bacteria,3TB3G@508458|Synergistetes	508458|Synergistetes	P	Iron-storage protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
WLSH2_k127_5130560_31	1521187.JPIM01000015_gene3744	2.153e-34	135.0	COG3339@1|root,COG3339@2|Bacteria,2G7DT@200795|Chloroflexi,377Q4@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
WLSH2_k127_5130560_13	1502724.FF80_00170	5.508e-93	316.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,3N64F@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prsA	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
WLSH2_k127_5130560_35	931276.Cspa_c42110	8.506e-23	106.0	COG1670@1|root,COG1670@2|Bacteria,1VW68@1239|Firmicutes,24JPF@186801|Clostridia,36JZH@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH2_k127_5130560_38	1121920.AUAU01000025_gene2333	4.693e-10	61.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
WLSH2_k127_5130560_26	926569.ANT_07880	2.511e-48	183.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
WLSH2_k127_5130560_33	926560.KE387023_gene2058	1.729e-29	123.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WLSH2_k127_5130560_15	944480.ATUV01000001_gene603	2.522e-85	289.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2M734@213113|Desulfurellales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WLSH2_k127_5130560_10	224325.AF_1199	4.61e-96	325.0	COG1788@1|root,arCOG01987@2157|Archaea,2XVRA@28890|Euryarchaeota,246WP@183980|Archaeoglobi	183980|Archaeoglobi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WLSH2_k127_5130560_0	926569.ANT_25540	2.665e-204	651.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
WLSH2_k127_5130560_39	1033738.CAEP01000100_gene332	2.304e-08	63.0	COG3393@1|root,COG3393@2|Bacteria,1V9KV@1239|Firmicutes,4HJ79@91061|Bacilli,26HFA@186818|Planococcaceae	91061|Bacilli	S	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
WLSH2_k127_5130560_4	1382306.JNIM01000001_gene3272	1.553e-141	460.0	COG0477@1|root,COG0477@2|Bacteria,2G5YG@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WLSH2_k127_5130560_23	479434.Sthe_3033	1.003e-52	191.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
WLSH2_k127_5130560_32	545695.TREAZ_3045	2.789e-34	140.0	COG2253@1|root,COG2253@2|Bacteria,2JB7K@203691|Spirochaetes	203691|Spirochaetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WLSH2_k127_5130560_34	1286171.EAL2_c08060	6.066e-26	116.0	28IZ9@1|root,2Z8WS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
WLSH2_k127_5133987_2	913865.DOT_0418	7.422e-45	180.0	COG1808@1|root,COG1808@2|Bacteria,1TRFZ@1239|Firmicutes,24PYJ@186801|Clostridia	186801|Clostridia	S	Hydrophobic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
WLSH2_k127_5133987_1	926550.CLDAP_06980	9.62e-47	175.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WLSH2_k127_5133987_0	926550.CLDAP_06970	1.54e-72	247.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
WLSH2_k127_513402_0	382464.ABSI01000013_gene1570	9.67e-229	755.0	COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,46U27@74201|Verrucomicrobia	74201|Verrucomicrobia	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc
WLSH2_k127_513402_2	926569.ANT_18180	3.557e-128	422.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_513402_1	1123376.AUIU01000012_gene1330	8.171e-157	514.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WLSH2_k127_513402_6	368407.Memar_2488	8.406e-08	56.0	COG1918@1|root,arCOG02102@2157|Archaea	2157|Archaea	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
WLSH2_k127_513402_3	926569.ANT_06040	9.032e-51	183.0	COG0735@1|root,COG0735@2|Bacteria,2G7G6@200795|Chloroflexi	200795|Chloroflexi	K	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WLSH2_k127_513402_4	589865.DaAHT2_2475	1.634e-24	104.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,42MZ4@68525|delta/epsilon subdivisions,2WJPB@28221|Deltaproteobacteria,2MJ8U@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
WLSH2_k127_5151711_3	997884.HMPREF1068_00165	1.882e-102	355.0	2CC7E@1|root,2Z7WG@2|Bacteria,4PJEQ@976|Bacteroidetes,2FRJV@200643|Bacteroidia,4AQCA@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5151711_1	1219084.AP014508_gene244	7.596e-143	468.0	COG2211@1|root,COG2211@2|Bacteria,2GCKM@200918|Thermotogae	200918|Thermotogae	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2
WLSH2_k127_5151711_4	1111479.AXAR01000001_gene318	2.445e-36	150.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HC0R@91061|Bacilli	91061|Bacilli	S	oxidoreductase	-	-	1.1.1.18,1.1.1.369,1.1.1.371	ko:K00010,ko:K16044	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951,R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_5151711_5	886377.Murru_2673	9.479e-17	88.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
WLSH2_k127_5151711_0	926550.CLDAP_16040	1.335e-209	660.0	COG1902@1|root,COG1902@2|Bacteria,2G872@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
WLSH2_k127_5151711_2	926550.CLDAP_16050	1.496e-113	376.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	-
WLSH2_k127_5158647_1	1120972.AUMH01000003_gene2909	3.376e-82	281.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli,2783N@186823|Alicyclobacillaceae	91061|Bacilli	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WLSH2_k127_5158647_4	926569.ANT_01630	8.915e-32	130.0	2CMS6@1|root,339SN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_5158647_5	1122605.KB893628_gene4444	2.3e-24	114.0	COG0451@1|root,COG0451@2|Bacteria,4NFZH@976|Bacteroidetes,1IQ5S@117747|Sphingobacteriia	976|Bacteroidetes	M	NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_4
WLSH2_k127_5158647_7	867845.KI911784_gene702	4.529e-10	70.0	COG2197@1|root,COG3055@1|root,COG2197@2|Bacteria,COG3055@2|Bacteria,2G6NU@200795|Chloroflexi,375Q0@32061|Chloroflexia	32061|Chloroflexia	KT	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Kelch_1,Kelch_4
WLSH2_k127_5158647_6	556267.HWAG_00265	8.352e-24	116.0	COG0535@1|root,COG0535@2|Bacteria,1NEM7@1224|Proteobacteria,43ADR@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WLSH2_k127_5158647_8	880070.Cycma_4668	6.86e-06	60.0	COG5368@1|root,COG5368@2|Bacteria,4NE34@976|Bacteroidetes,47M1C@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3131,Glycoamylase
WLSH2_k127_5158647_0	1123401.JHYQ01000003_gene2157	1.39e-98	329.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,1RTU6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WLSH2_k127_5158647_3	1205680.CAKO01000038_gene1730	1.588e-39	153.0	COG2606@1|root,COG2606@2|Bacteria,1R9YR@1224|Proteobacteria,2UUS6@28211|Alphaproteobacteria,2JXMI@204441|Rhodospirillales	204441|Rhodospirillales	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
WLSH2_k127_5158647_2	1123405.AUMM01000034_gene1692	1.481e-44	171.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
WLSH2_k127_5161922_2	913865.DOT_5073	2.597e-34	140.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,2642N@186807|Peptococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP pyruvate binding	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_5161922_3	1547437.LL06_01575	2.815e-16	87.0	2EH5Y@1|root,33AXU@2|Bacteria,1NRM6@1224|Proteobacteria,2UPAZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5161922_1	391037.Sare_1461	2.319e-135	456.0	2EXXE@1|root,33R6H@2|Bacteria,2H1T6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5161922_6	1120949.KB903329_gene9218	1.255e-11	69.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5161922_0	102129.Lepto7375DRAFT_0506	1.922e-141	481.0	COG2909@1|root,COG2909@2|Bacteria,1G3UH@1117|Cyanobacteria,1HDU6@1150|Oscillatoriales	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
WLSH2_k127_5161922_5	1187851.A33M_3313	4.569e-14	72.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
WLSH2_k127_5161922_4	102125.Xen7305DRAFT_00034050	2.799e-14	73.0	COG3093@1|root,COG3093@2|Bacteria,1G82A@1117|Cyanobacteria,3VN4Y@52604|Pleurocapsales	1117|Cyanobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WLSH2_k127_51924_9	926569.ANT_00370	1.384e-50	201.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH2_k127_51924_13	926569.ANT_00380	3.542e-46	174.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_51924_1	926569.ANT_00390	5.04e-137	455.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
WLSH2_k127_51924_4	926569.ANT_00400	4.793e-88	302.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_51924_3	357808.RoseRS_1101	1.716e-89	307.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH2_k127_51924_0	926569.ANT_31260	8.292e-243	757.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH2_k127_51924_14	926569.ANT_31270	4.715e-40	165.0	COG1808@1|root,COG1808@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
WLSH2_k127_51924_8	926569.ANT_31280	1.876e-54	195.0	COG4087@1|root,COG4087@2|Bacteria,2G99M@200795|Chloroflexi	200795|Chloroflexi	S	Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WLSH2_k127_51924_11	1125699.HMPREF9194_00243	3.727e-47	175.0	COG0346@1|root,COG0346@2|Bacteria,2J7HC@203691|Spirochaetes	203691|Spirochaetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
WLSH2_k127_51924_7	857087.Metme_2606	1.024e-56	210.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1XE4Z@135618|Methylococcales	135618|Methylococcales	G	Belongs to the HAD-like hydrolase superfamily	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
WLSH2_k127_51924_19	1463920.JOGB01000081_gene3516	1.752e-06	59.0	COG3595@1|root,COG3595@2|Bacteria,2GJZC@201174|Actinobacteria	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WLSH2_k127_51924_12	445973.CLOBAR_01439	6.058e-47	176.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,25R34@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WLSH2_k127_51924_15	1121870.AUAA01000024_gene1935	3.223e-39	154.0	COG0269@1|root,COG0269@2|Bacteria,4NINC@976|Bacteroidetes,1HZZQ@117743|Flavobacteriia	976|Bacteroidetes	G	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.2.43	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338	RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WLSH2_k127_51924_6	926566.Terro_1866	5.984e-79	275.0	COG1063@1|root,COG1063@2|Bacteria,3Y30Y@57723|Acidobacteria,2JKD7@204432|Acidobacteriia	204432|Acidobacteriia	C	Glucose dehydrogenase C-terminus	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_51924_5	180332.JTGN01000019_gene1311	4.737e-82	286.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24BVD@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WLSH2_k127_51924_10	272563.CD630_00450	3.553e-49	183.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	-	-	4.1.2.17,5.1.3.4	ko:K01628,ko:K03077	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
WLSH2_k127_51924_16	290402.Cbei_0541	4.287e-24	107.0	COG1762@1|root,COG1762@2|Bacteria,1VAHC@1239|Firmicutes,24M7N@186801|Clostridia,36KC7@31979|Clostridiaceae	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.200	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.5.1	-	-	PTS_EIIA_2
WLSH2_k127_51924_18	1140002.I570_02413	4.626e-08	58.0	COG3414@1|root,COG3414@2|Bacteria,1VA2P@1239|Firmicutes,4ID01@91061|Bacilli,4B5RP@81852|Enterococcaceae	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	-	-	-	-	-	-	-	-	-	-	PTS_IIB
WLSH2_k127_51924_2	556261.HMPREF0240_03479	3.437e-122	406.0	COG3775@1|root,COG3775@2|Bacteria,1TQ10@1239|Firmicutes,24ADE@186801|Clostridia,36DYN@31979|Clostridiaceae	186801|Clostridia	G	system Galactitol-specific IIC component	-	-	-	-	-	-	-	-	-	-	-	-	EIIC-GAT
WLSH2_k127_519791_3	1499967.BAYZ01000009_gene5356	9.1e-27	117.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_519791_0	926569.ANT_16190	2.848e-125	409.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
WLSH2_k127_519791_2	530564.Psta_0724	1.245e-51	192.0	COG1994@1|root,COG1994@2|Bacteria,2J0CK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WLSH2_k127_519791_1	926569.ANT_16180	4.226e-95	316.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WLSH2_k127_5271979_18	926569.ANT_16250	1.449e-34	141.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_16250|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5271979_0	926569.ANT_16230	3.274e-160	516.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi	200795|Chloroflexi	J	modification enzyme, MiaB family	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
WLSH2_k127_5271979_25	1121272.KB903251_gene763	1.275e-11	70.0	COG0457@1|root,COG2319@1|root,COG0457@2|Bacteria,COG2319@2|Bacteria,2GIWN@201174|Actinobacteria,4DEN6@85008|Micromonosporales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TIR_2,TPR_10,TPR_12,TPR_4,TPR_7
WLSH2_k127_5271979_4	926569.ANT_02380	3.458e-111	366.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WLSH2_k127_5271979_8	1163409.UUA_18147	4.283e-65	234.0	COG2010@1|root,COG2010@2|Bacteria,1MXXQ@1224|Proteobacteria,1SPE3@1236|Gammaproteobacteria,1X6TH@135614|Xanthomonadales	135614|Xanthomonadales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
WLSH2_k127_5271979_14	1408424.JHYI01000001_gene2042	6.967e-48	195.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1ZBBU@1386|Bacillus	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_5271979_19	1163409.UUA_06754	2.242e-33	132.0	COG1695@1|root,COG1695@2|Bacteria,1NJSY@1224|Proteobacteria,1SG6R@1236|Gammaproteobacteria,1X6UG@135614|Xanthomonadales	135614|Xanthomonadales	K	PadR family transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
WLSH2_k127_5271979_9	1163407.UU7_02182	5.262e-62	225.0	COG4709@1|root,COG4709@2|Bacteria,1NX5K@1224|Proteobacteria,1SPS6@1236|Gammaproteobacteria,1X34I@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
WLSH2_k127_5271979_2	204669.Acid345_3656	1.573e-124	409.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WLSH2_k127_5271979_10	945713.IALB_2065	3.353e-56	210.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	6.3.2.43	ko:K05827,ko:K05844	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RimK
WLSH2_k127_5271979_13	926569.ANT_22780	7.205e-49	181.0	COG1047@1|root,COG1047@2|Bacteria,2G744@200795|Chloroflexi	200795|Chloroflexi	G	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WLSH2_k127_5271979_12	926569.ANT_03400	9.4e-54	205.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_5271979_3	926569.ANT_02330	3.171e-113	371.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WLSH2_k127_5271979_6	926569.ANT_02340	9.051e-90	304.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WLSH2_k127_5271979_1	926569.ANT_02350	2.214e-146	472.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH2_k127_5271979_5	1499967.BAYZ01000104_gene3692	1.4e-94	323.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_5271979_15	324602.Caur_1140	2.406e-44	177.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	GGDEF,HAMP
WLSH2_k127_5271979_23	316274.Haur_4044	5.198e-13	76.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
WLSH2_k127_5271979_17	1382306.JNIM01000001_gene847	1.547e-38	166.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene847|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5271979_7	889378.Spiaf_2257	7.271e-83	289.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
WLSH2_k127_5271979_11	448385.sce4162	2.893e-55	210.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9,SCP2_2
WLSH2_k127_5271979_27	1206741.BAFX01000055_gene2466	1.387e-09	65.0	COG3832@1|root,COG3832@2|Bacteria,2IN0A@201174|Actinobacteria,4G2TT@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WLSH2_k127_5271979_21	497964.CfE428DRAFT_6673	9.157e-24	104.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH2_k127_5271979_24	1321784.HMPREF1987_01279	5.662e-12	74.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia	186801|Clostridia	K	PFAM Transcription factor CarD	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
WLSH2_k127_5271979_26	716544.wcw_0900	1.986e-11	71.0	COG5485@1|root,COG5485@2|Bacteria,2JHAF@204428|Chlamydiae	204428|Chlamydiae	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
WLSH2_k127_5271979_22	517418.Ctha_1599	3.948e-13	75.0	COG0724@1|root,COG0724@2|Bacteria,1FE64@1090|Chlorobi	1090|Chlorobi	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH2_k127_5273231_1	743719.PaelaDRAFT_0995	1.893e-28	121.0	COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli,26SKV@186822|Paenibacillaceae	91061|Bacilli	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_5273231_0	1499968.TCA2_1716	1.271e-73	259.0	COG2334@1|root,COG2334@2|Bacteria,1UZVZ@1239|Firmicutes,4HFK4@91061|Bacilli,26VV4@186822|Paenibacillaceae	91061|Bacilli	S	homoserine kinase type II (protein kinase fold)	hsK1	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_5273231_2	1403819.BATR01000093_gene2885	4.552e-05	50.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WLSH2_k127_5282218_1	1379698.RBG1_1C00001G0048	4.128e-65	229.0	COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6
WLSH2_k127_5282218_3	1379698.RBG1_1C00001G0049	1.007e-55	198.0	COG1908@1|root,COG1908@2|Bacteria,2NPFI@2323|unclassified Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	bamF	-	1.8.98.5,1.8.98.6	ko:K14127,ko:K14128	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2083	Fer4,FlpD,HTH_5
WLSH2_k127_5282218_0	693661.Arcve_1567	4.161e-255	802.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_5282218_2	880073.Calab_3047	3.465e-60	215.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
WLSH2_k127_5327817_16	926569.ANT_16800	1.937e-40	151.0	COG1003@1|root,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
WLSH2_k127_5327817_2	926569.ANT_16790	1.157e-184	587.0	COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WLSH2_k127_5327817_19	926569.ANT_16780	1.199e-33	133.0	COG0509@1|root,COG0509@2|Bacteria,2G6XE@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WLSH2_k127_5327817_8	251221.35211202	2.202e-81	287.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
WLSH2_k127_5327817_3	926569.ANT_13120	1.052e-175	567.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH2_k127_5327817_17	187272.Mlg_1165	2.891e-37	147.0	2CH3Z@1|root,32RP9@2|Bacteria,1MZF8@1224|Proteobacteria,1S8TF@1236|Gammaproteobacteria,1X19I@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
WLSH2_k127_5327817_12	926569.ANT_29130	5.869e-65	231.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
WLSH2_k127_5327817_4	926569.ANT_29120	6.45e-128	414.0	COG0348@1|root,COG0348@2|Bacteria,2G8SY@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
WLSH2_k127_5327817_10	357808.RoseRS_3403	2.687e-74	257.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,375NK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WLSH2_k127_5327817_1	1128421.JAGA01000003_gene3696	1.932e-189	610.0	COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH2_k127_5327817_7	1416759.AYMR01000011_gene505	4.684e-86	296.0	COG5621@1|root,COG5621@2|Bacteria,2GNHM@201174|Actinobacteria	201174|Actinobacteria	S	secreted hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CrtC
WLSH2_k127_5327817_0	883.DvMF_1147	4.424e-195	624.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,42NEP@68525|delta/epsilon subdivisions,2WPFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
WLSH2_k127_5327817_20	926550.CLDAP_36710	2.482e-27	114.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
WLSH2_k127_5327817_11	926550.CLDAP_37010	1.434e-72	254.0	COG0500@1|root,COG2226@2|Bacteria,2G6GD@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
WLSH2_k127_5327817_6	448385.sce5623	4.459e-89	297.0	COG0500@1|root,COG2226@2|Bacteria,1R7R7@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_5327817_9	1122138.AQUZ01000044_gene4502	5.654e-75	265.0	COG0701@1|root,COG0701@2|Bacteria,2HZBT@201174|Actinobacteria	201174|Actinobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
WLSH2_k127_5327817_15	926569.ANT_17620	1.063e-44	169.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WLSH2_k127_5327817_5	1220534.B655_1171	5.682e-102	341.0	COG0451@1|root,arCOG01369@2157|Archaea,2XUDM@28890|Euryarchaeota	28890|Euryarchaeota	M	NAD-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WLSH2_k127_5327817_14	1449126.JQKL01000014_gene3022	2.359e-49	186.0	COG1307@1|root,COG1307@2|Bacteria,1TYCV@1239|Firmicutes,248JV@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH2_k127_5327817_18	521674.Plim_1352	1.184e-34	143.0	COG0300@1|root,COG0300@2|Bacteria,2IZMH@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
WLSH2_k127_5327817_13	552811.Dehly_0372	1.026e-56	205.0	COG0312@1|root,COG0312@2|Bacteria,2GANY@200795|Chloroflexi,34CWZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH2_k127_5382592_0	926569.ANT_19070	1.813e-232	730.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WLSH2_k127_5382592_9	1385512.N784_10585	6.306e-16	82.0	2D7FD@1|root,32TNY@2|Bacteria,1VADP@1239|Firmicutes,4HKCW@91061|Bacilli,2YAKQ@289201|Pontibacillus	91061|Bacilli	S	Molecular chaperone DnaJ	ydhN1	-	-	-	-	-	-	-	-	-	-	-	DUF1992
WLSH2_k127_5382592_1	867903.ThesuDRAFT_02083	2.066e-132	453.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WCXQ@538999|Clostridiales incertae sedis	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_5382592_4	1380391.JIAS01000012_gene4124	7.083e-52	198.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,2JXWG@204441|Rhodospirillales	204441|Rhodospirillales	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652
WLSH2_k127_5382592_8	1429046.RR21198_0371	6.256e-18	89.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WLSH2_k127_5382592_10	324925.Ppha_1113	1.122e-14	78.0	2ESXY@1|root,33KG8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5382592_5	1173024.KI912148_gene3044	2.017e-39	158.0	COG0454@1|root,COG0456@2|Bacteria,1GGD2@1117|Cyanobacteria	1117|Cyanobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5382592_15	1453505.JASY01000003_gene1926	3.284e-05	48.0	COG0488@1|root,COG0488@2|Bacteria,4NES5@976|Bacteroidetes,1HXQY@117743|Flavobacteriia,2NS7R@237|Flavobacterium	976|Bacteroidetes	S	ABC transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WLSH2_k127_5382592_14	1453505.JASY01000003_gene2019	2.488e-08	61.0	2E32R@1|root,32Y2Y@2|Bacteria,4NVIY@976|Bacteroidetes,1ICZI@117743|Flavobacteriia,2NWDY@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5382592_6	875328.JDM601_3150	7.778e-37	143.0	2C945@1|root,32W5M@2|Bacteria,2I86M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	5.4.4.1	ko:K01865	ko00627,ko01120,map00627,map01120	-	-	-	ko00000,ko00001,ko01000	-	-	-	-
WLSH2_k127_5382592_11	234267.Acid_4874	7.506e-10	65.0	2ED19@1|root,336Y7@2|Bacteria,3Y95N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5382592_3	1133849.O3I_027875	1.854e-55	207.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4FX0N@85025|Nocardiaceae	201174|Actinobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_5382592_7	1035195.HMPREF9997_00805	1.342e-29	123.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,22KKN@1653|Corynebacteriaceae	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007,ko:K21787	ko00333,ko00620,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00333,map00620,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00374,M00837,M00838	R00199,R11662,R11673	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_5404641_8	926569.ANT_26420	8.82e-33	134.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_D23
WLSH2_k127_5404641_0	926569.ANT_26430	3.67e-280	885.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_5404641_4	266117.Rxyl_0848	9.808e-81	276.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_5404641_11	163908.KB235896_gene3431	1.693e-29	129.0	COG0344@1|root,COG0574@1|root,COG3848@1|root,COG0344@2|Bacteria,COG0574@2|Bacteria,COG3848@2|Bacteria,1G2NJ@1117|Cyanobacteria,1HJ5P@1161|Nostocales	1117|Cyanobacteria	GT	Pyruvate phosphate dikinase, PEP pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	G3P_acyltransf,PEP-utilizers,PPDK_N
WLSH2_k127_5404641_3	1173026.Glo7428_0224	1.27e-81	306.0	COG0344@1|root,COG0574@1|root,COG3848@1|root,COG0344@2|Bacteria,COG0574@2|Bacteria,COG3848@2|Bacteria,1G2NJ@1117|Cyanobacteria	1117|Cyanobacteria	GT	Pyruvate phosphate dikinase, PEP pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	G3P_acyltransf,PEP-utilizers,PPDK_N
WLSH2_k127_5404641_5	316274.Haur_3982	2.196e-67	261.0	COG1028@1|root,COG1028@2|Bacteria,2G9VV@200795|Chloroflexi,377FY@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_5404641_7	926569.ANT_26440	2.483e-40	158.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH2_k127_5404641_10	632245.CLP_1067	1.437e-29	125.0	2E66T@1|root,330VC@2|Bacteria,1VHCY@1239|Firmicutes,24MYI@186801|Clostridia,36NA0@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5404641_6	323850.Shew_0327	3.169e-53	194.0	COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,1SA2T@1236|Gammaproteobacteria,2QBDE@267890|Shewanellaceae	1236|Gammaproteobacteria	O	HupE / UreJ protein	-	-	-	ko:K03192	-	-	-	-	ko00000	-	-	-	HupE_UreJ
WLSH2_k127_5404641_2	926569.ANT_07000	6.696e-113	372.0	COG0111@1|root,COG0111@2|Bacteria,2G67B@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
WLSH2_k127_5404641_1	926569.ANT_06990	5.101e-209	661.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
WLSH2_k127_5404641_9	926569.ANT_06090	1.449e-32	139.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,WXG100
WLSH2_k127_5404641_12	316274.Haur_0685	5.421e-15	75.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH2_k127_5428305_19	1382306.JNIM01000001_gene1864	5.665e-44	169.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
WLSH2_k127_5428305_17	926569.ANT_11750	8.44e-59	212.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_5428305_6	926569.ANT_11760	1.817e-86	296.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_5428305_1	926569.ANT_11770	9.239e-234	736.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_5428305_0	926569.ANT_11780	6.191e-264	870.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WLSH2_k127_5428305_11	926569.ANT_11790	6.584e-83	283.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
WLSH2_k127_5428305_12	926569.ANT_11800	7.608e-82	294.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_5428305_4	926569.ANT_11800	1.39e-111	394.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_5428305_9	926569.ANT_11800	1.97e-84	301.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_5428305_8	926569.ANT_11800	8.32e-86	319.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_5428305_24	641524.ADICYQ_0962	5.969e-06	60.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PilZ,Response_reg
WLSH2_k127_5428305_7	926569.ANT_11800	5.168e-86	306.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_5428305_10	926569.ANT_11800	6.871e-84	295.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_5428305_23	290397.Adeh_3401	3.419e-07	63.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
WLSH2_k127_5428305_5	926569.ANT_11800	8.442e-88	315.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_5428305_20	1282361.ABAC402_00585	9.517e-15	88.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TY72@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SSF
WLSH2_k127_5428305_13	926569.ANT_11800	2.328e-76	287.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_5428305_14	926569.ANT_11820	1.063e-68	254.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
WLSH2_k127_5428305_16	926569.ANT_11820	6.294e-60	231.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
WLSH2_k127_5428305_3	926569.ANT_11830	2.158e-119	412.0	COG2203@1|root,COG3605@1|root,COG3829@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	virA	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K02482,ko:K02584,ko:K07673,ko:K10819	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00471,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,SpoIIE,dCache_1
WLSH2_k127_5428305_15	926569.ANT_11840	2.166e-68	235.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH2_k127_5428305_18	926569.ANT_11850	2.172e-46	173.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WLSH2_k127_5428305_22	388051.AUFE01000082_gene2276	6.496e-14	79.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	nagC	-	-	ko:K02003,ko:K02565,ko:K07058,ko:K15545	-	M00258	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1	-	-	MarR,ROK
WLSH2_k127_5428305_2	710696.Intca_3494	6.905e-139	454.0	COG1321@1|root,COG1321@2|Bacteria,2GN2R@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5428305_26	96561.Dole_0276	0.0001945	46.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42MUF@68525|delta/epsilon subdivisions,2WK25@28221|Deltaproteobacteria,2MJ8I@213118|Desulfobacterales	28221|Deltaproteobacteria	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
WLSH2_k127_5428305_25	1121481.AUAS01000039_gene5318	2.593e-05	48.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,47NCX@768503|Cytophagia	976|Bacteroidetes	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_5428305_21	768704.Desmer_4321	3.191e-14	74.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,26246@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_5441896_0	926550.CLDAP_21020	6.975e-65	229.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_5441896_2	269797.Mbar_A1346	1.374e-54	201.0	COG3293@1|root,arCOG03506@2157|Archaea	2157|Archaea	L	Transposase DDE domain	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF4096
WLSH2_k127_5441896_4	485913.Krac_0393	1.103e-23	114.0	COG1266@1|root,COG1266@2|Bacteria,2G772@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_5441896_3	36809.MAB_0923c	4.764e-30	134.0	COG1073@1|root,COG1073@2|Bacteria,2IA0F@201174|Actinobacteria,2372C@1762|Mycobacteriaceae	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
WLSH2_k127_5441896_1	1034807.FBFL15_1314	3.021e-58	208.0	COG3291@1|root,COG3291@2|Bacteria,4NHAX@976|Bacteroidetes,1HX1Y@117743|Flavobacteriia,2NT4M@237|Flavobacterium	976|Bacteroidetes	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
WLSH2_k127_5506533_34	1541065.JRFE01000073_gene3320	1.89e-06	50.0	COG3464@1|root,COG3464@2|Bacteria,1G42D@1117|Cyanobacteria,3VMW4@52604|Pleurocapsales	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_5506533_8	926569.ANT_30540	1.191e-120	405.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5506533_10	926569.ANT_01590	3.348e-88	306.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
WLSH2_k127_5506533_9	926569.ANT_14770	9.456e-105	347.0	COG2519@1|root,COG2519@2|Bacteria,2G8GD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
WLSH2_k127_5506533_22	926569.ANT_14780	1.56e-44	170.0	COG0494@1|root,COG0494@2|Bacteria,2G7AT@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_5506533_17	926569.ANT_14790	3.481e-57	207.0	COG1825@1|root,COG1825@2|Bacteria,2G7A4@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WLSH2_k127_5506533_3	926569.ANT_20700	1.489e-174	562.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
WLSH2_k127_5506533_21	926569.ANT_20710	4.048e-48	180.0	COG4478@1|root,COG4478@2|Bacteria,2G9EA@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
WLSH2_k127_5506533_35	671143.DAMO_1435	0.0006157	42.0	COG1028@1|root,COG1028@2|Bacteria,2NP35@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_5506533_13	658088.HMPREF0987_01698	2.359e-71	247.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,27IXU@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_5506533_23	926569.ANT_14620	3.291e-33	134.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WLSH2_k127_5506533_19	926569.ANT_14610	6.041e-52	187.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WLSH2_k127_5506533_33	926569.ANT_15060	1.147e-10	67.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WLSH2_k127_5506533_16	926569.ANT_15050	3.69e-58	214.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WLSH2_k127_5506533_0	1173028.ANKO01000042_gene858	3.849e-299	941.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria	1117|Cyanobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WLSH2_k127_5506533_31	395493.BegalDRAFT_0545	9.39e-14	79.0	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WLSH2_k127_5506533_11	1356852.N008_11050	6.504e-79	269.0	COG0586@1|root,COG0586@2|Bacteria,4NHQA@976|Bacteroidetes,47NAX@768503|Cytophagia	976|Bacteroidetes	S	PFAM SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
WLSH2_k127_5506533_6	926569.ANT_14740	3.3e-139	450.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WLSH2_k127_5506533_14	886293.Sinac_7569	1.022e-70	259.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
WLSH2_k127_5506533_7	926569.ANT_14730	3.527e-126	415.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi	200795|Chloroflexi	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WLSH2_k127_5506533_28	926569.ANT_22190	3.917e-24	111.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_5506533_26	318464.IO99_17370	2.215e-27	118.0	COG0537@1|root,COG0537@2|Bacteria,1VZUA@1239|Firmicutes,24PED@186801|Clostridia,36KWZ@31979|Clostridiaceae	186801|Clostridia	FG	adenosine 5'-monophosphoramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5506533_4	754252.PFREUD_03340	1.269e-156	511.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DQX3@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
WLSH2_k127_5506533_25	247490.KSU1_B0604	3.869e-28	122.0	2EABA@1|root,334FH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TIG
WLSH2_k127_5506533_5	1047013.AQSP01000100_gene587	6.091e-150	484.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_5506533_12	926569.ANT_29100	1.202e-74	257.0	COG1656@1|root,COG1656@2|Bacteria,2G6GZ@200795|Chloroflexi	200795|Chloroflexi	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
WLSH2_k127_5506533_18	933115.GPDM_06670	1.099e-54	199.0	COG3340@1|root,COG3340@2|Bacteria,1V7ZB@1239|Firmicutes,4HIGE@91061|Bacilli	91061|Bacilli	E	Belongs to the peptidase S51 family	-	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WLSH2_k127_5506533_1	926569.ANT_23480	2.928e-296	970.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
WLSH2_k127_5506533_15	926569.ANT_23470	4.179e-63	219.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi	200795|Chloroflexi	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WLSH2_k127_5506533_29	926554.KI912654_gene4506	2.334e-22	107.0	COG2267@1|root,COG2267@2|Bacteria,1WN05@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_5506533_20	324925.Ppha_0265	2.366e-50	181.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	chpA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
WLSH2_k127_5506533_27	324925.Ppha_0264	9e-26	108.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
WLSH2_k127_5545246_6	1125863.JAFN01000001_gene3475	7.76e-27	116.0	COG1569@1|root,COG1569@2|Bacteria,1Q9X7@1224|Proteobacteria,42X9V@68525|delta/epsilon subdivisions,2WT2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
WLSH2_k127_5545246_8	926569.ANT_28270	4.814e-18	85.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WLSH2_k127_5545246_5	926569.ANT_28280	3.487e-34	132.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WLSH2_k127_5545246_2	926569.ANT_28310	1.315e-134	436.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WLSH2_k127_5545246_0	926569.ANT_28320	0.0	1769.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
WLSH2_k127_5545246_4	926569.ANT_04780	9.279e-44	166.0	COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WLSH2_k127_5545246_7	926569.ANT_04790	9.683e-21	100.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	3.5.1.104	ko:K07273,ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_25,LysM
WLSH2_k127_5545246_3	880072.Desac_0095	1.351e-132	431.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
WLSH2_k127_5545246_9	981384.AEYW01000001_gene1563	5.346e-16	81.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K20976	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt
WLSH2_k127_5545246_1	981384.AEYW01000001_gene1562	5.248e-266	900.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
WLSH2_k127_5564053_0	562970.Btus_2406	3.367e-110	380.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,278ZI@186823|Alicyclobacillaceae	91061|Bacilli	C	Domain of unknown function (DUF3390)	yvfW	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
WLSH2_k127_5564053_2	926569.ANT_05600	5.433e-23	114.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5564053_4	502558.EGYY_29150	0.000958	45.0	2B2CD@1|root,31UWS@2|Bacteria,2HWAJ@201174|Actinobacteria,4CY6M@84998|Coriobacteriia	84998|Coriobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5564053_1	344747.PM8797T_14354	4.088e-30	129.0	COG0793@1|root,COG2234@1|root,COG0793@2|Bacteria,COG2234@2|Bacteria,2IXR2@203682|Planctomycetes	203682|Planctomycetes	M	PDZ domain (Also known as DHR or GLGF)	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M28
WLSH2_k127_5639664_29	1210884.HG799474_gene15133	5.788e-10	70.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
WLSH2_k127_5639664_3	926569.ANT_04920	7.951e-158	506.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_5639664_14	661478.OP10G_0459	1.1e-70	250.0	COG0083@1|root,COG0083@2|Bacteria	2|Bacteria	E	homoserine kinase activity	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620	GHMP_kinases_C,GHMP_kinases_N
WLSH2_k127_5639664_28	215803.DB30_2086	7.872e-12	72.0	COG2365@1|root,COG2365@2|Bacteria,1QX58@1224|Proteobacteria,43BXZ@68525|delta/epsilon subdivisions,2X78T@28221|Deltaproteobacteria,2YWT7@29|Myxococcales	28221|Deltaproteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
WLSH2_k127_5639664_0	1128421.JAGA01000002_gene789	2.534e-249	797.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2NPET@2323|unclassified Bacteria	2|Bacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_5639664_11	247490.KSU1_C1426	6.603e-93	315.0	COG0042@1|root,COG0042@2|Bacteria,2IYI5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
WLSH2_k127_5639664_5	981383.AEWH01000035_gene897	1.435e-149	487.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
WLSH2_k127_5639664_22	926569.ANT_13170	8.54e-49	186.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5639664_20	926569.ANT_00140	5.579e-56	198.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WLSH2_k127_5639664_6	926569.ANT_24820	2.706e-142	464.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WLSH2_k127_5639664_31	326427.Cagg_3261	0.0002649	53.0	295YQ@1|root,2ZT9I@2|Bacteria,2G9P7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5639664_30	443152.MDG893_09956	3.08e-06	57.0	2E5S7@1|root,330GQ@2|Bacteria,1NWVX@1224|Proteobacteria,1SP4N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WLSH2_k127_5639664_27	1303518.CCALI_02009	1.441e-34	141.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_5639664_18	1256908.HMPREF0373_01131	3.024e-64	226.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia	186801|Clostridia	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
WLSH2_k127_5639664_17	345219.Bcoa_1683	1.324e-67	241.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,1ZCFE@1386|Bacillus	91061|Bacilli	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
WLSH2_k127_5639664_13	926569.ANT_23200	4.862e-72	250.0	COG1540@1|root,COG1540@2|Bacteria,2G8DT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
WLSH2_k127_5639664_2	1254432.SCE1572_02095	1.478e-189	611.0	COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,43DUN@68525|delta/epsilon subdivisions,2WYXG@28221|Deltaproteobacteria,2Z0V5@29|Myxococcales	28221|Deltaproteobacteria	P	Castor and Pollux, part of voltage-gated ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Castor_Poll_mid
WLSH2_k127_5639664_9	926569.ANT_27700	7.012e-109	357.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
WLSH2_k127_5639664_8	926569.ANT_27130	1.49e-133	435.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi	200795|Chloroflexi	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WLSH2_k127_5639664_23	1123242.JH636434_gene4898	9.661e-43	174.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
WLSH2_k127_5639664_25	272134.KB731324_gene3814	3.949e-41	157.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
WLSH2_k127_5639664_15	118161.KB235922_gene5825	2.002e-70	243.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,3VJBK@52604|Pleurocapsales	1117|Cyanobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
WLSH2_k127_5639664_19	1124780.ANNU01000036_gene60	2.337e-58	221.0	COG4745@1|root,COG4745@2|Bacteria,4P4EE@976|Bacteroidetes	976|Bacteroidetes	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5639664_16	926569.ANT_00120	1.434e-69	246.0	COG1668@1|root,COG1668@2|Bacteria,2G76A@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
WLSH2_k127_5639664_10	926569.ANT_00110	6.823e-94	317.0	COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH2_k127_5639664_21	926569.ANT_00100	1.468e-51	190.0	COG5658@1|root,COG5658@2|Bacteria,2G714@200795|Chloroflexi	200795|Chloroflexi	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
WLSH2_k127_5639664_7	926569.ANT_00090	4.534e-135	436.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	2|Bacteria	O	PFAM band 7 protein	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH2_k127_5639664_26	926569.ANT_00080	9.372e-37	143.0	COG1725@1|root,COG1725@2|Bacteria,2G7C5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein GntR HTH	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
WLSH2_k127_5639664_4	926569.ANT_01650	2.271e-155	497.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
WLSH2_k127_5639664_12	926569.ANT_01660	2.363e-81	274.0	COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
WLSH2_k127_5639664_1	926569.ANT_01680	7.706e-199	630.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
WLSH2_k127_5642004_6	1121952.ATXT01000014_gene1542	1.24e-15	76.0	COG3549@1|root,COG3549@2|Bacteria,2IT6K@201174|Actinobacteria,4FQ75@85023|Microbacteriaceae	201174|Actinobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
WLSH2_k127_5642004_1	102125.Xen7305DRAFT_00034050	5.537e-44	162.0	COG3093@1|root,COG3093@2|Bacteria,1G82A@1117|Cyanobacteria,3VN4Y@52604|Pleurocapsales	1117|Cyanobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WLSH2_k127_5642004_3	927677.ALVU02000001_gene2434	2.057e-24	106.0	COG3514@1|root,COG3514@2|Bacteria,1G8GN@1117|Cyanobacteria	1117|Cyanobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
WLSH2_k127_5642004_2	449447.MAE_25610	2.081e-32	127.0	COG2929@1|root,COG2929@2|Bacteria,1G805@1117|Cyanobacteria	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
WLSH2_k127_5642004_0	118161.KB235922_gene2311	1.309e-79	276.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WLSH2_k127_5642004_4	118161.KB235922_gene2311	1.08e-17	86.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WLSH2_k127_5642004_5	224911.27349180	2.189e-17	91.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,3JSZR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
WLSH2_k127_5738584_1	1210884.HG799463_gene9589	2.482e-31	129.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
WLSH2_k127_5738584_2	243090.RB4303	1.146e-06	56.0	COG3464@1|root,COG3464@2|Bacteria,2J105@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,zf-IS66
WLSH2_k127_5738584_0	335543.Sfum_1032	5.184e-82	287.0	COG0501@1|root,COG0501@2|Bacteria,1NA37@1224|Proteobacteria,42Y90@68525|delta/epsilon subdivisions,2WUAP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WLSH2_k127_5798599_0	42256.RradSPS_0358	1.182e-289	915.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_5798599_20	1537994.JQFW01000002_gene3327	2.892e-06	55.0	2EBMG@1|root,335MQ@2|Bacteria,1NGDS@1224|Proteobacteria,1SCZ6@1236|Gammaproteobacteria,4694I@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5798599_11	43989.cce_3030	1.565e-48	190.0	COG1680@1|root,COG2931@1|root,COG1680@2|Bacteria,COG2931@2|Bacteria,1GE22@1117|Cyanobacteria,3KIGP@43988|Cyanothece	1117|Cyanobacteria	V	PFAM beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
WLSH2_k127_5798599_1	1408473.JHXO01000002_gene3998	6.7e-133	433.0	COG1680@1|root,COG1680@2|Bacteria,4NER1@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_5798599_6	391625.PPSIR1_06031	3.827e-69	252.0	COG4188@1|root,COG4188@2|Bacteria,1MW2N@1224|Proteobacteria,42W4F@68525|delta/epsilon subdivisions,2WR90@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DLH,PAF-AH_p_II
WLSH2_k127_5798599_15	329726.AM1_6084	1.596e-23	102.0	2DNVA@1|root,32ZBE@2|Bacteria,1GFXX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5798599_8	43989.cce_2707	1.72e-55	204.0	arCOG07533@1|root,2ZF5I@2|Bacteria,1GESQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
WLSH2_k127_5798599_10	693661.Arcve_0647	2.031e-50	187.0	arCOG07533@1|root,arCOG07533@2157|Archaea,2Y46E@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
WLSH2_k127_5798599_3	573413.Spirs_3837	5.465e-100	337.0	COG0604@1|root,COG0604@2|Bacteria,2JAG1@203691|Spirochaetes	203691|Spirochaetes	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2
WLSH2_k127_5798599_9	43989.cce_2707	1.586e-51	191.0	arCOG07533@1|root,2ZF5I@2|Bacteria,1GESQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
WLSH2_k127_5798599_2	1408254.T458_09100	6.13e-108	359.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WLSH2_k127_5798599_18	68170.KL590535_gene3916	3.712e-10	69.0	COG1672@1|root,COG1672@2|Bacteria,2I39W@201174|Actinobacteria	201174|Actinobacteria	K	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TIR_2,Trypsin_2
WLSH2_k127_5798599_4	63737.Npun_F4887	1.439e-86	297.0	COG0714@1|root,COG0714@2|Bacteria,1G2IM@1117|Cyanobacteria,1HU4Z@1161|Nostocales	1117|Cyanobacteria	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
WLSH2_k127_5798599_5	221288.JH992901_gene3668	2.175e-76	268.0	COG3825@1|root,COG3825@2|Bacteria,1G08I@1117|Cyanobacteria	1117|Cyanobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	-
WLSH2_k127_5798599_13	118168.MC7420_5579	7.711e-28	132.0	COG1262@1|root,COG1262@2|Bacteria,1G0ZT@1117|Cyanobacteria,1H92Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
WLSH2_k127_5798599_17	2074.JNYD01000008_gene1228	7.891e-16	93.0	COG0443@1|root,COG3391@1|root,COG4995@1|root,COG0443@2|Bacteria,COG3391@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,HSP70
WLSH2_k127_5798599_19	857087.Metme_3234	3.353e-07	64.0	COG2815@1|root,COG2815@2|Bacteria,1PGWR@1224|Proteobacteria,1SSGV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
WLSH2_k127_5798599_23	765420.OSCT_2724	0.0004035	45.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi,37519@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
WLSH2_k127_5798599_21	545694.TREPR_0187	6.086e-06	52.0	COG4118@1|root,COG4118@2|Bacteria,2J9CA@203691|Spirochaetes	203691|Spirochaetes	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WLSH2_k127_5798599_7	765420.OSCT_0637	5.602e-57	203.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH2_k127_5798599_22	515620.EUBELI_00409	8.264e-05	50.0	2E36C@1|root,32Y63@2|Bacteria,1W27F@1239|Firmicutes,255RB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5798599_16	324602.Caur_1689	9.553e-17	91.0	COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
WLSH2_k127_5798599_14	445961.IW15_02245	7.32e-26	114.0	COG2020@1|root,COG2020@2|Bacteria,4NXS4@976|Bacteroidetes,1I6PP@117743|Flavobacteriia,3ZQ7Y@59732|Chryseobacterium	976|Bacteroidetes	O	Protein-S-isoprenylcysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
WLSH2_k127_5798599_12	158190.SpiGrapes_0266	3.252e-41	154.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_5802879_19	574376.BAMA_15090	1.075e-20	100.0	COG0572@1|root,COG0572@2|Bacteria,1V8GA@1239|Firmicutes,4HINJ@91061|Bacilli,1ZH8Z@1386|Bacillus	91061|Bacilli	F	uridine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,PRK
WLSH2_k127_5802879_12	391735.Veis_2457	7.634e-62	222.0	COG1028@1|root,COG1028@2|Bacteria,1NTI2@1224|Proteobacteria,2VQ4K@28216|Betaproteobacteria,4AJQ5@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WLSH2_k127_5802879_20	243164.DET0533	6.33e-19	96.0	COG1011@1|root,COG1011@2|Bacteria,2G78N@200795|Chloroflexi,34D8N@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WLSH2_k127_5802879_6	1305836.AXVE01000003_gene2194	1.778e-141	462.0	COG0281@1|root,COG0281@2|Bacteria,1UYHB@1239|Firmicutes,4HDRG@91061|Bacilli,26EGN@186818|Planococcaceae	91061|Bacilli	C	Malic enzyme, N-terminal domain	mleA	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C,ACT_4,Malic_M,THF_DHG_CYH_C,malic
WLSH2_k127_5802879_3	926569.ANT_14860	2.104e-189	599.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
WLSH2_k127_5802879_18	1121946.AUAX01000019_gene7793	4.747e-25	108.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria,4DEVY@85008|Micromonosporales	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WLSH2_k127_5802879_17	909613.UO65_1835	6.096e-32	132.0	COG0406@1|root,COG0406@2|Bacteria,2GP71@201174|Actinobacteria,4E3GB@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	pgmB	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WLSH2_k127_5802879_4	517418.Ctha_2426	5.981e-178	568.0	COG0366@1|root,COG0366@2|Bacteria,1FFH6@1090|Chlorobi	1090|Chlorobi	C	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
WLSH2_k127_5802879_15	743719.PaelaDRAFT_3881	1.967e-47	188.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,26WPA@186822|Paenibacillaceae	91061|Bacilli	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
WLSH2_k127_5802879_9	251221.35211202	8.671e-105	361.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
WLSH2_k127_5802879_11	926569.ANT_10890	1.175e-85	287.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
WLSH2_k127_5802879_10	926569.ANT_31760	4.071e-89	298.0	COG1428@1|root,COG1428@2|Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
WLSH2_k127_5802879_1	926569.ANT_23500	1.855e-203	638.0	COG2768@1|root,COG2768@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21
WLSH2_k127_5802879_22	471875.RUMLAC_02593	0.0006343	43.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_5802879_2	204669.Acid345_1623	2.998e-201	632.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria,2JKQ8@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WLSH2_k127_5802879_7	926569.ANT_05010	4.513e-129	418.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WLSH2_k127_5802879_0	926569.ANT_12840	1.893e-232	743.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH2_k127_5802879_5	926569.ANT_12730	2.174e-168	539.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WLSH2_k127_5802879_16	604331.AUHY01000005_gene808	4.891e-35	138.0	COG0589@1|root,COG0589@2|Bacteria,1WJW6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_5802879_14	926569.ANT_29910	1.235e-51	190.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi	200795|Chloroflexi	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTPase_1
WLSH2_k127_5802879_21	1242864.D187_008640	9.915e-12	79.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42MDS@68525|delta/epsilon subdivisions,2WJM3@28221|Deltaproteobacteria,2YTXA@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
WLSH2_k127_5802879_8	926569.ANT_29620	4.43e-109	383.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WLSH2_k127_5814419_5	484770.UFO1_4369	1.027e-112	379.0	COG4987@1|root,COG4987@2|Bacteria,1UHN5@1239|Firmicutes,4H2NC@909932|Negativicutes	909932|Negativicutes	CO	thiol reductant ABC exporter, CydC subunit	cydC	-	-	ko:K06148,ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
WLSH2_k127_5814419_0	926569.ANT_09360	3.87e-219	686.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WLSH2_k127_5814419_10	926569.ANT_09370	1.742e-81	285.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
WLSH2_k127_5814419_16	926569.ANT_18900	2.702e-53	198.0	COG0340@1|root,COG0340@2|Bacteria,2G6WF@200795|Chloroflexi	200795|Chloroflexi	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
WLSH2_k127_5814419_14	751945.Theos_2091	1.039e-54	200.0	COG0321@1|root,COG0321@2|Bacteria,1WIJ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WLSH2_k127_5814419_4	1303518.CCALI_01587	4.703e-137	450.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	ko:K00103,ko:K16653	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
WLSH2_k127_5814419_13	1192034.CAP_3530	3.876e-58	212.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
WLSH2_k127_5814419_18	1242864.D187_009133	3.725e-40	165.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions,2WNS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
WLSH2_k127_5814419_9	926569.ANT_25680	5.673e-84	288.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WLSH2_k127_5814419_3	926569.ANT_25670	2.937e-137	454.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
WLSH2_k127_5814419_1	926569.ANT_30160	1.298e-193	610.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_5814419_15	1499967.BAYZ01000008_gene5408	4.162e-54	205.0	COG2931@1|root,COG2931@2|Bacteria,2NQ7A@2323|unclassified Bacteria	2|Bacteria	Q	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Calx-beta,DUF4214,DUF4347,Peptidase_C11,SLH,SWM_repeat
WLSH2_k127_5814419_12	357808.RoseRS_0017	2.706e-60	215.0	COG1309@1|root,COG1309@2|Bacteria,2GAFT@200795|Chloroflexi,375ZP@32061|Chloroflexia	32061|Chloroflexia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH2_k127_5814419_20	196162.Noca_4965	3.288e-16	88.0	28PN6@1|root,2ZCB1@2|Bacteria,2INN5@201174|Actinobacteria,4DW3I@85009|Propionibacteriales	201174|Actinobacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
WLSH2_k127_5814419_23	1266925.JHVX01000002_gene944	2.984e-05	52.0	2EI68@1|root,33BXK@2|Bacteria,1NH2E@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5814419_8	240292.Ava_3981	2.493e-91	310.0	COG0451@1|root,COG0451@2|Bacteria,1GDDM@1117|Cyanobacteria	1117|Cyanobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5814419_7	292415.Tbd_1114	3.787e-107	356.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WLSH2_k127_5814419_19	1459636.NTE_01426	1.18e-30	130.0	COG1814@1|root,arCOG01096@2157|Archaea,41T13@651137|Thaumarchaeota	651137|Thaumarchaeota	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WLSH2_k127_5814419_6	1123400.KB904767_gene3417	3.16e-112	376.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1S1GA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WLSH2_k127_5814419_11	1173027.Mic7113_2149	7.933e-71	255.0	COG2114@1|root,COG3322@1|root,COG2114@2|Bacteria,COG3322@2|Bacteria,1G4NW@1117|Cyanobacteria,1H9ST@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,Guanylate_cyc,HAMP
WLSH2_k127_5814419_21	324925.Ppha_1113	8.007e-11	64.0	2ESXY@1|root,33KG8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5814419_2	871963.Desdi_0890	2.206e-145	473.0	COG0477@1|root,COG0477@2|Bacteria,1TPHW@1239|Firmicutes,2492B@186801|Clostridia,260N8@186807|Peptococcaceae	186801|Clostridia	P	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_5814419_17	391625.PPSIR1_31263	4.902e-47	173.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKYM@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	GT	Phosphoenolpyruvate synthase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_5832140_3	1173020.Cha6605_1137	1.839e-172	550.0	COG1233@1|root,COG1233@2|Bacteria,1GCDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WLSH2_k127_5832140_11	679926.Mpet_1639	2.291e-44	173.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y4MT@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
WLSH2_k127_5832140_4	357808.RoseRS_1829	2.594e-166	530.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WLSH2_k127_5832140_10	926569.ANT_16940	7.727e-53	202.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WLSH2_k127_5832140_16	1336243.JAEA01000002_gene2859	3.83e-07	62.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,1JTQ0@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM cyclic nucleotide-binding	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
WLSH2_k127_5832140_5	926569.ANT_18200	1.218e-157	504.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
WLSH2_k127_5832140_8	926569.ANT_18220	8.754e-82	276.0	COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K03615	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
WLSH2_k127_5832140_1	926569.ANT_18230	2.753e-257	806.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5JF@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
WLSH2_k127_5832140_7	926569.ANT_18240	1.004e-96	321.0	COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
WLSH2_k127_5832140_18	667121.ET1_12_00200	9.638e-06	51.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S assembly protein IscX	iscX	GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
WLSH2_k127_5832140_13	1122994.AUFR01000019_gene403	1.51e-14	81.0	COG2345@1|root,COG2345@2|Bacteria,2GN8W@201174|Actinobacteria,4DQCB@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	sufR	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,MarR_2
WLSH2_k127_5832140_19	1287116.X734_01795	2.609e-05	49.0	COG2334@1|root,COG2334@2|Bacteria,1MXTW@1224|Proteobacteria,2U31H@28211|Alphaproteobacteria,43PDX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_5832140_12	861299.J421_0531	4.059e-17	87.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
WLSH2_k127_5832140_6	861299.J421_0531	1.439e-143	465.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
WLSH2_k127_5832140_14	861299.J421_0531	2.662e-13	72.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	gabT	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
WLSH2_k127_5832140_2	981369.JQMJ01000004_gene5607	1.84e-176	564.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,2NEM7@228398|Streptacidiphilus	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WLSH2_k127_5832140_0	247634.GPB2148_3142	0.0	1028.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,1RZZE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the GcvT family	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
WLSH2_k127_5832140_15	1121927.GOHSU_04_00230	1.369e-11	66.0	COG1983@1|root,COG1983@2|Bacteria,2GQG0@201174|Actinobacteria,4GF7U@85026|Gordoniaceae	201174|Actinobacteria	KT	PspC domain	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
WLSH2_k127_5832140_9	926550.CLDAP_02830	9.335e-60	210.0	COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi	200795|Chloroflexi	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
WLSH2_k127_5832140_20	1340434.AXVA01000007_gene5144	3.1e-05	56.0	COG4655@1|root,COG4655@2|Bacteria,1V25X@1239|Firmicutes,4ITZ4@91061|Bacilli,1ZIQ4@1386|Bacillus	91061|Bacilli	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
WLSH2_k127_5832140_17	1280944.HY17_07450	1.241e-06	60.0	COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria,43YJM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
WLSH2_k127_5852837_4	1121382.JQKG01000006_gene3440	3.269e-16	90.0	COG1074@1|root,COG1074@2|Bacteria,1WIAY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WLSH2_k127_5852837_0	1173264.KI913949_gene1260	3.618e-55	211.0	COG4974@1|root,COG4974@2|Bacteria,1G9V9@1117|Cyanobacteria,1HD0Y@1150|Oscillatoriales	1117|Cyanobacteria	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
WLSH2_k127_5852837_3	485913.Krac_6321	1.093e-16	83.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32,HTH_33
WLSH2_k127_5852837_6	485913.Krac_1655	1.242e-05	49.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32,HTH_33
WLSH2_k127_5852837_5	926560.KE387023_gene1157	1.207e-15	79.0	COG2128@1|root,COG2128@2|Bacteria,1WMFR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WLSH2_k127_5852837_2	926560.KE387023_gene1157	1.201e-26	112.0	COG2128@1|root,COG2128@2|Bacteria,1WMFR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WLSH2_k127_5852837_1	357808.RoseRS_3898	6.755e-29	121.0	COG0673@1|root,COG0673@2|Bacteria,2G7R0@200795|Chloroflexi,377Y3@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WLSH2_k127_5862611_0	926569.ANT_10860	0.0	2116.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WLSH2_k127_5911117_3	926569.ANT_04530	2.098e-19	89.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
WLSH2_k127_5911117_1	926569.ANT_17610	3.272e-60	214.0	COG1611@1|root,COG1611@2|Bacteria,2G6P1@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WLSH2_k127_5911117_4	658187.LDG_6943	4.669e-19	98.0	COG0726@1|root,COG0726@2|Bacteria,1NHC2@1224|Proteobacteria,1SGBD@1236|Gammaproteobacteria,1JCCV@118969|Legionellales	118969|Legionellales	G	Protein of unknown function (DUF3298)	yjeA	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
WLSH2_k127_5911117_0	287.DR97_5978	2.022e-63	222.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
WLSH2_k127_5911117_6	479434.Sthe_0930	3.433e-05	48.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,2G7WU@200795|Chloroflexi,27YR8@189775|Thermomicrobia	189775|Thermomicrobia	L	helicase superfamily c-terminal domain	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
WLSH2_k127_5911117_2	926569.ANT_15100	3.509e-40	155.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH2_k127_5911117_5	926569.ANT_21000	6.143e-08	59.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
WLSH2_k127_5984883_2	926569.ANT_07760	1.281e-130	423.0	COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WLSH2_k127_5984883_1	926569.ANT_07770	1.214e-133	430.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WLSH2_k127_5984883_4	525904.Tter_0098	1.71e-102	348.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
WLSH2_k127_5984883_11	926569.ANT_29030	1.106e-24	106.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
WLSH2_k127_5984883_3	926569.ANT_15760	1.146e-104	350.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WLSH2_k127_5984883_6	1128421.JAGA01000002_gene1836	3.748e-83	290.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
WLSH2_k127_5984883_7	926569.ANT_06810	4.29e-66	232.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_06810|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5984883_8	1183438.GKIL_1265	4.575e-52	186.0	2A3W2@1|root,30SE9@2|Bacteria,1GDAU@1117|Cyanobacteria	1117|Cyanobacteria	L	PD-(D/E)XK endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_5
WLSH2_k127_5984883_12	926569.ANT_04290	4.057e-21	103.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WLSH2_k127_5984883_9	1123400.KB904769_gene2917	3.611e-38	149.0	COG3038@1|root,COG3038@2|Bacteria	2|Bacteria	C	cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	DUF3611,Ni_hydr_CYTB
WLSH2_k127_5984883_13	304371.MCP_0686	1.698e-07	57.0	COG1917@1|root,arCOG03002@2157|Archaea	2157|Archaea	S	Cupin 2 conserved barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,DUF2249
WLSH2_k127_5984883_10	395961.Cyan7425_2574	8.103e-26	119.0	COG0664@1|root,COG0664@2|Bacteria,1G3SU@1117|Cyanobacteria,3KKQJ@43988|Cyanothece	1117|Cyanobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_5984883_5	518766.Rmar_2285	1.634e-85	295.0	COG4243@1|root,COG4243@2|Bacteria,4PJI6@976|Bacteroidetes,1FK8W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5984883_0	278963.ATWD01000001_gene2861	9.708e-178	569.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria,2JJPA@204432|Acidobacteriia	204432|Acidobacteriia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
WLSH2_k127_5990993_0	1541065.JRFE01000001_gene2509	3.933e-145	473.0	COG3547@1|root,COG3547@2|Bacteria,1G077@1117|Cyanobacteria,3VNMH@52604|Pleurocapsales	1117|Cyanobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
WLSH2_k127_5990993_1	926569.ANT_22190	1.43e-59	225.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_6001492_22	926569.ANT_10450	3.155e-59	212.0	COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
WLSH2_k127_6001492_4	926569.ANT_10460	2.14e-211	667.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WLSH2_k127_6001492_7	1128421.JAGA01000002_gene1909	8.044e-142	466.0	COG1008@1|root,COG1008@2|Bacteria,2NQKN@2323|unclassified Bacteria	2|Bacteria	C	Proton-conducting membrane transporter	ndhD	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iJN678.ndhD2	Oxidored_q5_N,Proton_antipo_M
WLSH2_k127_6001492_9	926569.ANT_10480	7.015e-133	439.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WLSH2_k127_6001492_15	926569.ANT_10520	5.04e-78	273.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WLSH2_k127_6001492_32	926569.ANT_10530	1.631e-18	87.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WLSH2_k127_6001492_17	926569.ANT_10540	1.583e-69	243.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
WLSH2_k127_6001492_5	926569.ANT_10550	6.959e-194	619.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH2_k127_6001492_29	1250005.PHEL85_1377	1.207e-44	169.0	COG4276@1|root,COG4276@2|Bacteria,4NQJG@976|Bacteroidetes,1I17G@117743|Flavobacteriia,3VVMZ@52959|Polaribacter	976|Bacteroidetes	S	SRPBCC domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
WLSH2_k127_6001492_21	485913.Krac_0932	1.539e-59	212.0	COG1670@1|root,COG1670@2|Bacteria,2G6X6@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH2_k127_6001492_25	1448139.AI20_02565	2.349e-50	189.0	COG0110@1|root,COG0110@2|Bacteria,1RKM6@1224|Proteobacteria,1S7HK@1236|Gammaproteobacteria,1Y6EU@135624|Aeromonadales	135624|Aeromonadales	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
WLSH2_k127_6001492_39	419665.Maeo_0832	4.596e-08	56.0	COG0348@1|root,arCOG02772@2157|Archaea	2157|Archaea	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_10,Fer4_5,Fer4_9
WLSH2_k127_6001492_28	349521.HCH_01563	2.408e-46	178.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1XR8Q@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WLSH2_k127_6001492_12	926569.ANT_03400	1.863e-106	360.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_6001492_14	1385517.N800_08670	1.717e-92	325.0	COG1361@1|root,COG1361@2|Bacteria,1MUQC@1224|Proteobacteria,1RYHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Peptidase M11 gametolysin	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc,Peptidase_M11
WLSH2_k127_6001492_1	926569.ANT_10570	5.495e-307	957.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WLSH2_k127_6001492_31	926569.ANT_10580	1.415e-29	119.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WLSH2_k127_6001492_6	926550.CLDAP_07120	1.197e-153	494.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WLSH2_k127_6001492_40	285535.JOEY01000033_gene9340	4.597e-07	58.0	2C1AE@1|root,32QZN@2|Bacteria,2IIC0@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_6001492_20	697284.ERIC2_c09080	8.758e-60	215.0	COG3694@1|root,COG3694@2|Bacteria,1V1MN@1239|Firmicutes,4HFXH@91061|Bacilli,26S9D@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH2_k127_6001492_18	697284.ERIC2_c09070	1.321e-61	222.0	COG4587@1|root,COG4587@2|Bacteria,1UZ3Y@1239|Firmicutes,4HFHM@91061|Bacilli,26V8Z@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH2_k127_6001492_30	797209.ZOD2009_02960	1.046e-43	167.0	arCOG01782@1|root,arCOG01782@2157|Archaea,2XTX4@28890|Euryarchaeota,23TWF@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_6001492_13	402777.KB235904_gene3704	1.133e-101	342.0	COG2114@1|root,COG2114@2|Bacteria,1G4IH@1117|Cyanobacteria,1H7YG@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
WLSH2_k127_6001492_41	5911.EAR85563	9.47e-07	59.0	2CN9Y@1|root,2QUR8@2759|Eukaryota	5911.EAR85563|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6001492_11	1382306.JNIM01000001_gene3601	3.208e-108	366.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2G5VX@200795|Chloroflexi	200795|Chloroflexi	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_6001492_38	1230341.MJ3_02817	8.633e-10	65.0	COG0572@1|root,COG0572@2|Bacteria,1V8GA@1239|Firmicutes,4HINJ@91061|Bacilli	91061|Bacilli	F	uridine kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,PRK
WLSH2_k127_6001492_8	661478.OP10G_2269	2.327e-135	439.0	COG0274@1|root,COG0274@2|Bacteria	2|Bacteria	F	deoxyribose-phosphate aldolase activity	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WLSH2_k127_6001492_0	7739.XP_002589830.1	0.0	1071.0	COG1012@1|root,KOG2450@2759|Eukaryota,38CQ7@33154|Opisthokonta,3BH9X@33208|Metazoa,3CZ2T@33213|Bilateria,48BFC@7711|Chordata	33208|Metazoa	C	Aldehyde dehydrogenase 16 family member A1	aldh16a1	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH2_k127_6001492_42	596320.NEIFL0001_0138	4.567e-05	47.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2VWIX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_6001492_34	1163408.UU9_04462	4.063e-13	70.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SABY@1236|Gammaproteobacteria,1X85U@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_6001492_16	545695.TREAZ_1866	8.165e-73	257.0	COG0407@1|root,COG0407@2|Bacteria,2J8ZX@203691|Spirochaetes	203691|Spirochaetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WLSH2_k127_6001492_3	313606.M23134_04526	2.244e-233	738.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,47NSK@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
WLSH2_k127_6001492_10	1237149.C900_03398	7.499e-116	388.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_6001492_36	926569.ANT_07760	1.03e-11	71.0	COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WLSH2_k127_6001492_2	324925.Ppha_2833	1.406e-255	799.0	COG0318@1|root,COG0318@2|Bacteria,1FDAB@1090|Chlorobi	1090|Chlorobi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_6001492_23	526226.Gbro_4678	2.957e-55	198.0	2DXPV@1|root,32V3V@2|Bacteria,2IDU1@201174|Actinobacteria,4GG6T@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6001492_27	1540221.JQNI01000002_gene1131	2.098e-46	176.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WLSH2_k127_6001492_19	269797.Mbar_A3082	3.027e-60	212.0	COG4894@1|root,arCOG03995@2157|Archaea,2XXXJ@28890|Euryarchaeota,2NB1N@224756|Methanomicrobia	224756|Methanomicrobia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
WLSH2_k127_6001492_26	1487953.JMKF01000079_gene4182	1.516e-48	182.0	arCOG09511@1|root,2Z9DH@2|Bacteria,1GBD1@1117|Cyanobacteria	1117|Cyanobacteria	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
WLSH2_k127_6001492_33	1206720.BAFQ01000255_gene5519	2.337e-16	84.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,4G0CF@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
WLSH2_k127_6001492_24	96561.Dole_1695	4.151e-51	190.0	COG1145@1|root,COG1145@2|Bacteria,1MW11@1224|Proteobacteria,42NUY@68525|delta/epsilon subdivisions,2WK01@28221|Deltaproteobacteria,2MMY1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH2_k127_6030834_16	926569.ANT_19230	3.984e-54	196.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WLSH2_k127_6030834_22	1120999.JONM01000011_gene1670	5.717e-41	157.0	COG2453@1|root,COG2453@2|Bacteria,1QZXA@1224|Proteobacteria	1224|Proteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
WLSH2_k127_6030834_33	1123242.JH636435_gene1054	4.652e-17	93.0	COG1723@1|root,COG1723@2|Bacteria,2J0AJ@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6030834_25	926569.ANT_15740	5.718e-32	136.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
WLSH2_k127_6030834_10	926569.ANT_15730	7.409e-86	298.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WLSH2_k127_6030834_21	555079.Toce_0227	7.006e-43	159.0	COG3829@1|root,COG3829@2|Bacteria,1VBSS@1239|Firmicutes	1239|Firmicutes	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6030834_4	926569.ANT_15720	1.746e-158	511.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WLSH2_k127_6030834_5	926569.ANT_09020	3.613e-153	493.0	COG0477@1|root,COG2814@2|Bacteria,2G8W5@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_6030834_13	370438.PTH_1451	4.937e-64	231.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,2612R@186807|Peptococcaceae	186801|Clostridia	U	type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WLSH2_k127_6030834_35	1267535.KB906767_gene4956	1.654e-13	76.0	COG2197@1|root,COG2197@2|Bacteria,3Y8IZ@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WLSH2_k127_6030834_0	926569.ANT_02690	2.656e-263	821.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
WLSH2_k127_6030834_40	163908.KB235896_gene4769	2.278e-08	55.0	COG1669@1|root,COG1669@2|Bacteria,1G8W8@1117|Cyanobacteria,1HP9T@1161|Nostocales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
WLSH2_k127_6030834_38	579137.Metvu_0403	3.995e-09	61.0	COG2361@1|root,arCOG05024@2157|Archaea,2XYZR@28890|Euryarchaeota,23RQP@183939|Methanococci	183939|Methanococci	S	to PID 1652090 percent identity	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
WLSH2_k127_6030834_6	671143.DAMO_2519	9.569e-145	469.0	COG1373@1|root,COG1373@2|Bacteria,2NQZ6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143,HTH_24,HTH_IclR
WLSH2_k127_6030834_42	767817.Desgi_1956	4.024e-07	52.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WLSH2_k127_6030834_36	641149.HMPREF9016_01532	5.988e-12	67.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2VWIX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_6030834_44	641149.HMPREF9016_01714	0.0008326	44.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2VWIX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_6030834_29	195522.BD01_0197	2.836e-24	106.0	COG1848@1|root,arCOG02222@2157|Archaea,2Y1YE@28890|Euryarchaeota,24558@183968|Thermococci	183968|Thermococci	V	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_6030834_43	671143.DAMO_2522	8.518e-06	51.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
WLSH2_k127_6030834_32	297246.lpp0701	2.003e-22	99.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1S8Z3@1236|Gammaproteobacteria,1JEQX@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_6030834_31	105559.Nwat_2566	1.626e-23	101.0	COG1724@1|root,COG1724@2|Bacteria,1Q0UZ@1224|Proteobacteria,1SRX7@1236|Gammaproteobacteria,1X190@135613|Chromatiales	135613|Chromatiales	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
WLSH2_k127_6030834_30	1499967.BAYZ01000048_gene2715	2.974e-24	104.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6030834_41	103690.17130612	2.463e-08	58.0	COG2852@1|root,COG2852@2|Bacteria,1G6SC@1117|Cyanobacteria,1HNXA@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH2_k127_6030834_19	1380391.JIAS01000012_gene4124	4.2e-50	192.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria,2JXWG@204441|Rhodospirillales	204441|Rhodospirillales	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652
WLSH2_k127_6030834_37	1122917.KB899663_gene2758	2.48e-09	62.0	2DMXT@1|root,32UAK@2|Bacteria,1U8NH@1239|Firmicutes,4ICTZ@91061|Bacilli,272ST@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6030834_28	926550.CLDAP_34640	2.551e-24	106.0	2DMXT@1|root,32UAK@2|Bacteria,2G7DN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6030834_14	926569.ANT_00790	1.83e-55	201.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K03977,ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko03009	-	-	-	G3P_acyltransf
WLSH2_k127_6030834_8	926569.ANT_00800	1.567e-128	421.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
WLSH2_k127_6030834_17	1307761.L21SP2_0556	4.056e-54	194.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
WLSH2_k127_6030834_9	1449343.JQLQ01000002_gene1851	7.72e-115	377.0	COG1028@1|root,COG1028@2|Bacteria,1TRQB@1239|Firmicutes,4HAY3@91061|Bacilli,27GSR@186828|Carnobacteriaceae	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_6030834_3	1449343.JQLQ01000002_gene1850	1.866e-171	553.0	COG1233@1|root,COG1233@2|Bacteria,1UU71@1239|Firmicutes,4IFA2@91061|Bacilli,27H4R@186828|Carnobacteriaceae	91061|Bacilli	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
WLSH2_k127_6030834_20	195103.CPF_2928	6.132e-43	161.0	2D5AS@1|root,32TIN@2|Bacteria,1VA4E@1239|Firmicutes,24JJQ@186801|Clostridia,36JKZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B561
WLSH2_k127_6030834_11	478741.JAFS01000001_gene1555	8.526e-73	258.0	28I4Y@1|root,2Z88D@2|Bacteria,46VRF@74201|Verrucomicrobia,37GMA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6030834_39	1049564.TevJSym_aj00150	1.402e-08	61.0	2DSPU@1|root,33GZC@2|Bacteria,1NJ5W@1224|Proteobacteria,1SHAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WLSH2_k127_6030834_2	926550.CLDAP_12700	4.275e-187	603.0	COG0326@1|root,COG0326@2|Bacteria,2G60B@200795|Chloroflexi	200795|Chloroflexi	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
WLSH2_k127_6030834_26	211165.AJLN01000153_gene671	1.257e-27	114.0	COG0500@1|root,COG2226@2|Bacteria,1GAXU@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_6030834_34	316274.Haur_3471	4.465e-16	81.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
WLSH2_k127_6030834_1	794903.OPIT5_23600	2.959e-216	701.0	COG2352@1|root,COG2352@2|Bacteria,46SIN@74201|Verrucomicrobia,3K7TR@414999|Opitutae	414999|Opitutae	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
WLSH2_k127_6030834_23	926560.KE387023_gene2407	1.517e-35	141.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WLSH2_k127_6030834_15	7897.ENSLACP00000010670	1.495e-54	196.0	COG1437@1|root,KOG2589@2759|Eukaryota,3A4QC@33154|Opisthokonta,3BRFI@33208|Metazoa,3D8WI@33213|Bilateria,48EHS@7711|Chordata,49BAX@7742|Vertebrata	33208|Metazoa	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
WLSH2_k127_6030834_18	926569.ANT_03840	1.29e-52	190.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WLSH2_k127_6030834_12	926569.ANT_03850	3.326e-65	244.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi	200795|Chloroflexi	T	SMART helix-turn-helix domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
WLSH2_k127_6054867_1	383372.Rcas_1022	4.912e-45	167.0	COG2211@1|root,COG2211@2|Bacteria,2G6B9@200795|Chloroflexi,3767E@32061|Chloroflexia	32061|Chloroflexia	G	major facilitator superfamily MFS_1	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
WLSH2_k127_6054867_0	383372.Rcas_4420	7.839e-123	414.0	COG3039@1|root,COG3039@2|Bacteria,2G8AJ@200795|Chloroflexi,377UG@32061|Chloroflexia	32061|Chloroflexia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
WLSH2_k127_6054867_2	298654.FraEuI1c_5237	7.625e-07	51.0	COG1840@1|root,COG1840@2|Bacteria,2HU3D@201174|Actinobacteria,4EWS7@85013|Frankiales	201174|Actinobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6125269_25	1229172.JQFA01000004_gene1781	2.351e-32	129.0	COG5433@1|root,COG5433@2|Bacteria,1G7IY@1117|Cyanobacteria,1HHE3@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_6125269_12	272134.KB731324_gene3814	1.757e-81	280.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
WLSH2_k127_6125269_9	555088.DealDRAFT_2880	4.689e-105	350.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes	1239|Firmicutes	I	Lipid kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WLSH2_k127_6125269_16	926569.ANT_26780	1.091e-59	212.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_6125269_5	926569.ANT_11560	7.87e-115	389.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH2_k127_6125269_17	1382356.JQMP01000004_gene363	1.123e-54	200.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_6125269_6	926569.ANT_11580	3.188e-111	368.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
WLSH2_k127_6125269_18	926569.ANT_20630	4.484e-53	201.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
WLSH2_k127_6125269_3	926569.ANT_20640	6.804e-150	484.0	COG2201@1|root,COG4963@1|root,COG2201@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi	200795|Chloroflexi	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA,Response_reg
WLSH2_k127_6125269_2	926569.ANT_20650	3.412e-230	720.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WLSH2_k127_6125269_10	926569.ANT_20660	1.647e-104	348.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
WLSH2_k127_6125269_8	926569.ANT_20670	6.812e-106	352.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
WLSH2_k127_6125269_23	926569.ANT_20680	5.705e-46	175.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi	200795|Chloroflexi	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WLSH2_k127_6125269_15	926569.ANT_20690	7.524e-60	213.0	COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi	200795|Chloroflexi	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
WLSH2_k127_6125269_13	326427.Cagg_0017	7.704e-72	249.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WLSH2_k127_6125269_26	344747.PM8797T_30012	3.573e-26	112.0	COG1539@1|root,COG1539@2|Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
WLSH2_k127_6125269_24	926569.ANT_20530	6.128e-44	170.0	COG0682@1|root,COG0682@2|Bacteria,2G8YW@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH2_k127_6125269_22	926569.ANT_20540	6.4e-47	175.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi	200795|Chloroflexi	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_6125269_20	272134.KB731324_gene6608	1.872e-49	181.0	2C0PI@1|root,32DX7@2|Bacteria,1GJPP@1117|Cyanobacteria,1HG1B@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6125269_4	306281.AJLK01000008_gene5848	1.605e-148	477.0	COG2334@1|root,COG2334@2|Bacteria,1G1QD@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_6125269_14	1449063.JMLS01000002_gene1458	3.674e-60	227.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli,26TF3@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	yunD	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos
WLSH2_k127_6125269_1	926569.ANT_18080	1.798e-296	922.0	COG0021@1|root,COG0021@2|Bacteria,2G63Z@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WLSH2_k127_6125269_19	1142394.PSMK_26510	2.302e-50	183.0	COG0698@1|root,COG0698@2|Bacteria,2IZSB@203682|Planctomycetes	203682|Planctomycetes	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WLSH2_k127_6125269_0	926569.ANT_18060	3.877e-316	993.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
WLSH2_k127_6125269_7	768671.ThimaDRAFT_4426	1.164e-110	366.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria,1SQA0@1236|Gammaproteobacteria,1X16W@135613|Chromatiales	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6157074_5	1121479.AUBS01000002_gene3634	2.753e-05	52.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1PPWK@1224|Proteobacteria,2TYY3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
WLSH2_k127_6157074_0	243231.GSU1538	7.174e-137	446.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N38@68525|delta/epsilon subdivisions,2WK56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
WLSH2_k127_6157074_2	926569.ANT_16370	7.111e-36	148.0	COG0406@1|root,COG0406@2|Bacteria,2G7D2@200795|Chloroflexi	200795|Chloroflexi	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WLSH2_k127_6157074_4	1131462.DCF50_p1603	1.641e-07	56.0	2ENWS@1|root,33GHQ@2|Bacteria,1VQNU@1239|Firmicutes,24TC6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6157074_1	926569.ANT_18190	4.659e-96	319.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
WLSH2_k127_6308916_6	926569.ANT_06330	5.047e-43	158.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH2_k127_6308916_1	926569.ANT_06320	3.783e-164	532.0	COG0763@1|root,COG0763@2|Bacteria	2|Bacteria	M	lipid-A-disaccharide synthase activity	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	Capsule_synth
WLSH2_k127_6308916_0	926569.ANT_06310	2.252e-190	604.0	COG1134@1|root,COG1134@2|Bacteria	2|Bacteria	GM	teichoic acid transport	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
WLSH2_k127_6308916_4	234267.Acid_4640	1.522e-108	358.0	COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
WLSH2_k127_6308916_2	926569.ANT_06290	8.91e-147	471.0	COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi	200795|Chloroflexi	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
WLSH2_k127_6308916_3	326427.Cagg_1543	5.665e-132	428.0	COG0451@1|root,COG0451@2|Bacteria,2GBWQ@200795|Chloroflexi,3774S@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WLSH2_k127_6308916_5	926569.ANT_06280	1.488e-51	186.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	DUF4388,HTH_24,MarR_2
WLSH2_k127_6314939_0	926569.ANT_10450	7.413e-256	797.0	COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
WLSH2_k127_6314939_11	926550.CLDAP_08800	1.136e-32	129.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
WLSH2_k127_6314939_9	926569.ANT_10430	4.948e-45	168.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WLSH2_k127_6314939_5	926569.ANT_10420	1.051e-102	347.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WLSH2_k127_6314939_10	926569.ANT_10410	6.398e-42	156.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WLSH2_k127_6314939_7	266117.Rxyl_0771	7.628e-55	202.0	arCOG06048@1|root,31EJQ@2|Bacteria,2GPSC@201174|Actinobacteria,4CQDB@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6314939_1	1128421.JAGA01000003_gene3664	1.865e-217	688.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	steT	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
WLSH2_k127_6314939_4	266117.Rxyl_0772	4.055e-112	370.0	COG2129@1|root,COG2129@2|Bacteria,2IJW1@201174|Actinobacteria,4CQ37@84995|Rubrobacteria	84995|Rubrobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6314939_6	522306.CAP2UW1_2085	3.742e-95	321.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,1KQA5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	phosphate transporter	-	-	-	ko:K03306,ko:K16322	-	-	-	-	ko00000,ko02000	2.A.20,2.A.20.1	-	-	PHO4
WLSH2_k127_6314939_8	706587.Desti_4215	2.227e-45	171.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
WLSH2_k127_6314939_3	1168065.DOK_11349	1.718e-160	514.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,1RNJE@1236|Gammaproteobacteria,1J58R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	phosphoserine phosphatase	serB	GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	iE2348C_1286.E2348C_4686,iEC042_1314.EC042_4885,iECO26_1355.ECO26_5594,iECSF_1327.ECSF_4321,iECUMN_1333.ECUMN_5012,iETEC_1333.ETEC_4743,iPC815.YPO0442,iUMNK88_1353.UMNK88_5307	ACT_6,HAD,Hydrolase
WLSH2_k127_6314939_2	1121920.AUAU01000013_gene1701	1.347e-197	625.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_6341066_15	926569.ANT_04570	1.909e-67	233.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
WLSH2_k127_6341066_3	383372.Rcas_4326	1.403e-252	792.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WLSH2_k127_6341066_0	580327.Tthe_2605	4.103e-285	888.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F44@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_6341066_2	1499684.CCNP01000018_gene965	4.592e-256	810.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,36EMB@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_6341066_12	316274.Haur_3982	2.406e-81	279.0	COG1028@1|root,COG1028@2|Bacteria,2G9VV@200795|Chloroflexi,377FY@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_6341066_30	326427.Cagg_0238	7.263e-10	66.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WLSH2_k127_6341066_28	1121904.ARBP01000008_gene3289	8.8e-14	84.0	COG2319@1|root,COG2319@2|Bacteria,4PP7D@976|Bacteroidetes,47WB4@768503|Cytophagia	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,WD40
WLSH2_k127_6341066_8	926569.ANT_28680	6.697e-104	346.0	COG2746@1|root,COG2746@2|Bacteria,2G6YM@200795|Chloroflexi	200795|Chloroflexi	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
WLSH2_k127_6341066_24	237368.SCABRO_00409	7.671e-40	154.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	BB1022	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WLSH2_k127_6341066_7	926569.ANT_14300	6.893e-107	351.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_6341066_25	1122221.JHVI01000014_gene1428	5.04e-34	136.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH2_k127_6341066_5	926569.ANT_15110	1.721e-122	395.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_6341066_27	926569.ANT_15120	7.301e-22	96.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6341066_20	926569.ANT_15130	1.482e-46	173.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
WLSH2_k127_6341066_6	926569.ANT_15140	3.115e-111	377.0	COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
WLSH2_k127_6341066_11	926569.ANT_15150	1.255e-93	316.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
WLSH2_k127_6341066_1	926569.ANT_15160	8.214e-274	855.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
WLSH2_k127_6341066_18	326427.Cagg_0444	1.484e-50	187.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi,375QR@32061|Chloroflexia	32061|Chloroflexia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WLSH2_k127_6341066_14	316274.Haur_4010	1.595e-69	246.0	COG1475@1|root,COG1475@2|Bacteria,2G735@200795|Chloroflexi,375G7@32061|Chloroflexia	32061|Chloroflexia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
WLSH2_k127_6341066_19	1123237.Salmuc_04333	6.882e-49	186.0	COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria,2TUAG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EM	Belongs to the DapA family	dapAb	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WLSH2_k127_6341066_29	1341151.ASZU01000006_gene2893	4.105e-11	73.0	COG2755@1|root,COG2755@2|Bacteria,1VAXZ@1239|Firmicutes,4HNDB@91061|Bacilli	91061|Bacilli	E	Lysophospholipase L1 and related esterases	ycsK	GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0044238,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WLSH2_k127_6341066_32	1202532.FF52_10433	0.0005671	49.0	COG3631@1|root,COG3631@2|Bacteria,4NSBA@976|Bacteroidetes,1I5KV@117743|Flavobacteriia,2NZ3X@237|Flavobacterium	976|Bacteroidetes	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WLSH2_k127_6341066_31	1223410.KN050846_gene1249	9.185e-06	54.0	2B7X4@1|root,32143@2|Bacteria,4NNUI@976|Bacteroidetes,1I2MC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WLSH2_k127_6341066_21	1449126.JQKL01000025_gene2405	1.525e-44	176.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,269FT@186813|unclassified Clostridiales	186801|Clostridia	K	Periplasmic binding protein-like domain	rbsR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
WLSH2_k127_6341066_4	765420.OSCT_2127	8.659e-141	470.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6341066_23	765420.OSCT_2126	1.794e-40	158.0	2A540@1|root,30TSN@2|Bacteria,2G9TT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6341066_10	926569.ANT_10920	1.202e-95	320.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WLSH2_k127_6341066_26	525904.Tter_0583	2.925e-30	128.0	2AZDP@1|root,31RMA@2|Bacteria,2NRKB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
WLSH2_k127_6341066_22	926569.ANT_10910	3.212e-44	174.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
WLSH2_k127_6341066_17	926569.ANT_10910	7.985e-55	208.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
WLSH2_k127_6341066_9	1307761.L21SP2_1483	1.278e-103	344.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
WLSH2_k127_6341066_16	1307761.L21SP2_1484	4.098e-65	241.0	COG3639@1|root,COG3639@2|Bacteria,2J6TW@203691|Spirochaetes	203691|Spirochaetes	U	ABC transporter (Permease)	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
WLSH2_k127_6341066_13	1131269.AQVV01000005_gene388	5.392e-72	258.0	COG3639@1|root,COG3639@2|Bacteria	2|Bacteria	P	organic phosphonate transmembrane transporter activity	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
WLSH2_k127_6375426_1	383372.Rcas_1300	5.641e-112	398.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WLSH2_k127_6375426_0	1499967.BAYZ01000180_gene4412	8.516e-241	758.0	COG0334@1|root,COG0517@1|root,COG0334@2|Bacteria,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	aer	-	1.4.1.2	ko:K03406,ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,ko02020,ko02030,map00220,map00250,map00430,map00910,map01100,map02020,map02030	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000,ko02035	-	-	-	CBS,HATPase_c,HisKA,MCPsignal,Response_reg,SpoIIE
WLSH2_k127_6375426_6	644283.Micau_0490	0.0006456	51.0	COG0454@1|root,COG1246@1|root,COG0456@2|Bacteria,COG1246@2|Bacteria,2INZ5@201174|Actinobacteria,4DE3A@85008|Micromonosporales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_6375426_4	743719.PaelaDRAFT_3775	6.61e-10	61.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
WLSH2_k127_6375426_2	324602.Caur_3230	9.682e-67	234.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi,377YJ@32061|Chloroflexia	32061|Chloroflexia	K	Sigma-70, region 4 type 2	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WLSH2_k127_6375426_3	316274.Haur_1105	1.872e-38	158.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
WLSH2_k127_6375426_5	324602.Caur_3229	1.558e-09	68.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WLSH2_k127_6411047_1	32057.KB217483_gene9527	5.195e-141	466.0	COG4467@1|root,COG4467@2|Bacteria,1G4QI@1117|Cyanobacteria,1HPJG@1161|Nostocales	1117|Cyanobacteria	S	Involved in initiation control of chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
WLSH2_k127_6411047_0	1242864.D187_006134	4.074e-144	474.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1R0NC@1224|Proteobacteria,43CZ0@68525|delta/epsilon subdivisions,2X877@28221|Deltaproteobacteria,2Z2EZ@29|Myxococcales	28221|Deltaproteobacteria	C	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_6411047_3	33035.JPJF01000020_gene3474	8.266e-19	88.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1UYA0@1239|Firmicutes	1239|Firmicutes	GT	Phosphoenolpyruvate synthase	yvkC	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_6411047_4	857087.Metme_3933	7.065e-12	74.0	COG2020@1|root,COG2020@2|Bacteria,1N936@1224|Proteobacteria,1SCXB@1236|Gammaproteobacteria,1XFKD@135618|Methylococcales	135618|Methylococcales	M	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
WLSH2_k127_6411047_2	485913.Krac_4241	1.415e-79	270.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_648285_2	1541959.KQ51_00282	2.033e-123	423.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppsA	-	2.7.9.2,6.5.1.3	ko:K01007,ko:K14415	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_648285_9	1121423.JONT01000020_gene1382	6.23e-23	107.0	COG1309@1|root,COG1309@2|Bacteria,1VCGN@1239|Firmicutes,24T8E@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH2_k127_648285_0	452637.Oter_2238	2.856e-224	707.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WLSH2_k127_648285_4	926569.ANT_20830	1.693e-104	351.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
WLSH2_k127_648285_10	1196323.ALKF01000184_gene3593	2.289e-21	102.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,26R0Q@186822|Paenibacillaceae	91061|Bacilli	G	phosphoglycerate	gpmB	-	5.4.2.12	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WLSH2_k127_648285_3	926569.ANT_29590	1.255e-111	368.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
WLSH2_k127_648285_1	926569.ANT_20160	2.168e-185	585.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	wecE	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	iE2348C_1286.E2348C_4092,iEC55989_1330.EC55989_4263,iECIAI1_1343.ECIAI1_3978,iECIAI39_1322.ECIAI39_2996,iECO103_1326.ECO103_4373,iECO111_1330.ECO111_4617,iECO26_1355.ECO26_4795,iECUMN_1333.ECUMN_4316,iECW_1372.ECW_m4089,iEKO11_1354.EKO11_4565,iSSON_1240.SSON_3963,iWFL_1372.ECW_m4089	DegT_DnrJ_EryC1
WLSH2_k127_648285_6	1167006.UWK_02419	3.662e-63	228.0	COG0399@1|root,COG0399@2|Bacteria,1NWV9@1224|Proteobacteria,43056@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_648285_8	344747.PM8797T_27617	7.858e-56	202.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31
WLSH2_k127_648285_7	314270.RB2083_3937	6.579e-58	208.0	COG0224@1|root,COG0224@2|Bacteria,1QUME@1224|Proteobacteria,2U32Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
WLSH2_k127_648285_5	926569.ANT_20140	1.977e-91	310.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	2|Bacteria	M	PFAM Glycosyl transferase family 2	wcqE	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
WLSH2_k127_6541218_1	485913.Krac_1655	2.786e-74	262.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_32,HTH_33
WLSH2_k127_6541218_3	316274.Haur_1044	1.1e-52	199.0	COG0596@1|root,COG0596@2|Bacteria,2G8UW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WLSH2_k127_6541218_10	406327.Mevan_0500	2.477e-11	70.0	COG0456@1|root,arCOG00833@2157|Archaea,2XYEG@28890|Euryarchaeota,23R5N@183939|Methanococci	183939|Methanococci	K	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WLSH2_k127_6541218_11	1408424.JHYI01000040_gene2358	7.463e-05	45.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli,1ZJ93@1386|Bacillus	91061|Bacilli	S	Transcriptional Coactivator p15 (PC4)	XK26_06125	-	-	-	-	-	-	-	-	-	-	-	PC4
WLSH2_k127_6541218_7	292459.STH3171	6.098e-23	102.0	COG0724@1|root,COG0724@2|Bacteria,1VBMH@1239|Firmicutes,24NVR@186801|Clostridia	186801|Clostridia	S	Rna-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH2_k127_6541218_9	105422.BBPM01000005_gene6165	3.585e-14	74.0	2EJ7M@1|root,33CYT@2|Bacteria,2GWJB@201174|Actinobacteria,2NK09@228398|Streptacidiphilus	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6541218_6	1382358.JHVN01000017_gene1361	2.863e-28	115.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli	91061|Bacilli	S	protein conserved in bacteria	XK26_06125	-	-	-	-	-	-	-	-	-	-	-	PC4
WLSH2_k127_6541218_2	1227500.C494_10370	1.939e-66	236.0	COG0508@1|root,arCOG01706@2157|Archaea,2XUGY@28890|Euryarchaeota,23V33@183963|Halobacteria	183963|Halobacteria	C	COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
WLSH2_k127_6541218_0	69042.WH5701_04060	1.954e-94	316.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1GYG1@1129|Synechococcus	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WLSH2_k127_6541218_4	69042.WH5701_04060	1.179e-37	147.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1GYG1@1129|Synechococcus	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WLSH2_k127_655339_5	658655.HMPREF0988_01739	1.437e-48	189.0	28MZN@1|root,2ZB6B@2|Bacteria,1TTSM@1239|Firmicutes,24A84@186801|Clostridia,27SEB@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_655339_0	926569.ANT_18640	7.467e-275	869.0	COG3808@1|root,COG3808@2|Bacteria,2G5N7@200795|Chloroflexi	200795|Chloroflexi	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
WLSH2_k127_655339_10	1303518.CCALI_00819	7.252e-21	97.0	COG0316@1|root,COG0316@2|Bacteria	2|Bacteria	S	protein maturation	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
WLSH2_k127_655339_6	926569.ANT_18580	8.137e-40	159.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
WLSH2_k127_655339_7	926569.ANT_18580	1.777e-28	124.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
WLSH2_k127_655339_12	485913.Krac_0943	1.195e-06	57.0	2DRCD@1|root,33B7A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_655339_9	926569.ANT_11370	4.194e-25	115.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
WLSH2_k127_655339_8	926569.ANT_11380	1.465e-27	117.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
WLSH2_k127_655339_2	926569.ANT_11390	6.621e-121	394.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WLSH2_k127_655339_1	926569.ANT_11400	3.143e-201	654.0	COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
WLSH2_k127_655339_4	926569.ANT_21000	1.944e-51	186.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
WLSH2_k127_655339_3	1499968.TCA2_2957	3.082e-88	298.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,26QNA@186822|Paenibacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WLSH2_k127_655339_11	323850.Shew_1243	1.554e-20	95.0	COG4104@1|root,COG4104@2|Bacteria,1RJTU@1224|Proteobacteria,1T0PZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Lysine-specific metallo-endopeptidase	-	-	3.4.24.20	ko:K08646	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Aspzincin_M35
WLSH2_k127_6579635_8	485913.Krac_8563	1.65e-33	137.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
WLSH2_k127_6579635_10	94624.Bpet1407	3.148e-09	62.0	2EHAG@1|root,33B2C@2|Bacteria,1NE9A@1224|Proteobacteria	1224|Proteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
WLSH2_k127_6579635_9	266835.14025798	1.91e-29	131.0	COG1959@1|root,COG1959@2|Bacteria,1QY6K@1224|Proteobacteria,2U80M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28
WLSH2_k127_6579635_0	94624.Bpet1409	1.912e-239	759.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_6579635_4	485913.Krac_2962	1.135e-72	254.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
WLSH2_k127_6579635_7	1121382.JQKG01000006_gene3481	1.429e-37	148.0	COG3437@1|root,COG3437@2|Bacteria,1WJ3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
WLSH2_k127_6579635_5	383372.Rcas_1313	7.95e-67	233.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WLSH2_k127_6579635_6	1089550.ATTH01000001_gene164	2.69e-47	179.0	COG0637@1|root,COG0637@2|Bacteria,4PIUH@976|Bacteroidetes,1FKCU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.23	ko:K19270	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2
WLSH2_k127_6579635_3	861299.J421_0757	3.431e-120	393.0	COG1023@1|root,COG1023@2|Bacteria	2|Bacteria	G	D-gluconate metabolic process	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WLSH2_k127_6579635_1	324602.Caur_0501	6.036e-159	515.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
WLSH2_k127_6579635_2	324602.Caur_0549	5.653e-140	462.0	COG2128@1|root,COG2128@2|Bacteria,2G7WP@200795|Chloroflexi,376HC@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
WLSH2_k127_6579635_11	402881.Plav_2596	0.0001344	46.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	ko:K19156	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
WLSH2_k127_6588918_11	526225.Gobs_1160	1.136e-72	280.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EUR9@85013|Frankiales	201174|Actinobacteria	P	WD-40 repeat-containing protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,TIR_2,WD40
WLSH2_k127_6588918_38	1235798.C817_00299	4.767e-07	64.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
WLSH2_k127_6588918_37	517417.Cpar_1958	2.081e-07	65.0	2DV1F@1|root,33TI2@2|Bacteria,1FEEI@1090|Chlorobi	1090|Chlorobi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6588918_32	316274.Haur_2979	9.227e-16	89.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM_3,CHAP,RsgI_N,SLH
WLSH2_k127_6588918_16	446470.Snas_6020	1.405e-53	205.0	2E809@1|root,332EJ@2|Bacteria,2H3RK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6588918_39	1415775.U729_2273	0.0001377	55.0	COG3291@1|root,COG4724@1|root,COG3291@2|Bacteria,COG4724@2|Bacteria,1TPGB@1239|Firmicutes,24AII@186801|Clostridia,36G7G@31979|Clostridiaceae	186801|Clostridia	G	Glycosyl hydrolase family 85	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_85,PKD
WLSH2_k127_6588918_33	1123070.KB899249_gene350	1.305e-14	87.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia,2IVDG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WLSH2_k127_6588918_28	1280692.AUJL01000022_gene523	1.55e-30	139.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,36DJ1@31979|Clostridiaceae	186801|Clostridia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WLSH2_k127_6588918_21	1519464.HY22_02245	1.797e-42	162.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
WLSH2_k127_6588918_6	1278073.MYSTI_03069	1.226e-94	328.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42RDN@68525|delta/epsilon subdivisions,2WMR0@28221|Deltaproteobacteria,2YUAJ@29|Myxococcales	28221|Deltaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WLSH2_k127_6588918_1	926569.ANT_14270	5.097e-176	555.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WLSH2_k127_6588918_3	926569.ANT_14260	5.579e-141	455.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi	200795|Chloroflexi	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WLSH2_k127_6588918_27	497965.Cyan7822_4279	1.081e-30	136.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria,1G233@1117|Cyanobacteria	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NACHT
WLSH2_k127_6588918_31	1382306.JNIM01000001_gene4102	1.862e-18	90.0	COG1063@1|root,COG1063@2|Bacteria,2G7NV@200795|Chloroflexi	200795|Chloroflexi	C	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_6588918_22	986075.CathTA2_1560	4.302e-40	160.0	COG1063@1|root,COG1063@2|Bacteria,1UY29@1239|Firmicutes,4HE5C@91061|Bacilli	91061|Bacilli	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_6588918_10	926554.KI912637_gene3425	1.427e-73	263.0	COG0584@1|root,COG0584@2|Bacteria,1WKK6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WLSH2_k127_6588918_19	272134.KB731324_gene2254	2.271e-48	186.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,PD40,SpoIIE,TIR_2,WD40
WLSH2_k127_6588918_8	522306.CAP2UW1_2609	2.546e-90	328.0	COG1192@1|root,COG1357@1|root,COG1787@1|root,COG2319@1|root,COG5635@1|root,COG1192@2|Bacteria,COG1357@2|Bacteria,COG1787@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
WLSH2_k127_6588918_18	525904.Tter_2170	8.097e-49	183.0	COG0778@1|root,COG0778@2|Bacteria,2NRS1@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_6588918_7	1163409.UUA_16980	1.715e-93	317.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RU20@1236|Gammaproteobacteria,1X9AU@135614|Xanthomonadales	135614|Xanthomonadales	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WLSH2_k127_6588918_4	489825.LYNGBM3L_09830	9.652e-108	390.0	COG0683@1|root,COG0683@2|Bacteria,1G1WJ@1117|Cyanobacteria,1H79U@1150|Oscillatoriales	1117|Cyanobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH2_k127_6588918_13	1480694.DC28_14010	1.136e-66	260.0	COG1653@1|root,COG1653@2|Bacteria,2J59Z@203691|Spirochaetes	203691|Spirochaetes	G	solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_6588918_9	1144275.COCOR_04444	3.506e-77	264.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,42SMW@68525|delta/epsilon subdivisions,2WPP1@28221|Deltaproteobacteria,2YUYP@29|Myxococcales	28221|Deltaproteobacteria	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH2_k127_6588918_15	926550.CLDAP_20430	1.041e-60	220.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
WLSH2_k127_6588918_35	926569.ANT_19750	1.332e-08	57.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH2_k127_6588918_26	56780.SYN_03642	1.643e-32	129.0	COG1225@1|root,COG1225@2|Bacteria,1P69S@1224|Proteobacteria,432W3@68525|delta/epsilon subdivisions,2WXMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH2_k127_6588918_5	926569.ANT_20800	1.491e-95	323.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2G6C3@200795|Chloroflexi	200795|Chloroflexi	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6588918_0	926569.ANT_22870	1.424e-184	586.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WLSH2_k127_6588918_2	926569.ANT_18700	1.091e-144	498.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
WLSH2_k127_6588918_12	926569.ANT_18710	1.012e-69	239.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi	200795|Chloroflexi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WLSH2_k127_6588918_29	1395587.P364_0121970	2.206e-24	115.0	arCOG09511@1|root,30C0Z@2|Bacteria,1VZ01@1239|Firmicutes,4HY49@91061|Bacilli	91061|Bacilli	S	FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
WLSH2_k127_6588918_25	926569.ANT_08660	5.807e-35	136.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WLSH2_k127_6588918_17	926569.ANT_08670	4.056e-49	184.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi	200795|Chloroflexi	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
WLSH2_k127_6588918_30	1247963.JPHU01000007_gene1627	1.509e-23	105.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Response regulator receiver	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WLSH2_k127_6588918_20	1382356.JQMP01000003_gene1897	1.058e-47	177.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
WLSH2_k127_6588918_23	1254432.SCE1572_05510	5.624e-40	156.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_6588918_34	1487953.JMKF01000073_gene3678	8.429e-12	70.0	COG0659@1|root,COG0659@2|Bacteria,1G3AY@1117|Cyanobacteria,1H9Q2@1150|Oscillatoriales	1117|Cyanobacteria	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
WLSH2_k127_6588918_24	1089553.Tph_c21880	1.702e-35	142.0	COG0815@1|root,COG0815@2|Bacteria,1V095@1239|Firmicutes,24B2E@186801|Clostridia	186801|Clostridia	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WLSH2_k127_6633273_30	1115515.EV102420_50_00010	6.21e-05	48.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,3XQ3W@561|Escherichia	1236|Gammaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
WLSH2_k127_6633273_25	319795.Dgeo_2191	2.415e-20	99.0	2DBFF@1|root,2Z8YA@2|Bacteria	2|Bacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
WLSH2_k127_6633273_27	319795.Dgeo_2191	1.045e-11	73.0	2DBFF@1|root,2Z8YA@2|Bacteria	2|Bacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_4,HTH_Tnp_4
WLSH2_k127_6633273_21	304371.MCP_0732	1.897e-41	156.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WLSH2_k127_6633273_13	1035308.AQYY01000001_gene2006	6.193e-63	222.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,264ZM@186807|Peptococcaceae	186801|Clostridia	S	conserved protein (DUF2174)	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
WLSH2_k127_6633273_4	158190.SpiGrapes_1961	6.656e-109	362.0	28PJ3@1|root,2ZC8W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6633273_10	880073.Calab_2864	1.154e-78	278.0	COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WLSH2_k127_6633273_12	926569.ANT_22190	1.286e-69	260.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_6633273_29	161934.XP_010678870.1	8.718e-11	75.0	KOG4351@1|root,KOG4582@1|root,KOG4351@2759|Eukaryota,KOG4582@2759|Eukaryota,37HVT@33090|Viridiplantae,3GCJ1@35493|Streptophyta	35493|Streptophyta	V	ubiquitin binding	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1,ZZ
WLSH2_k127_6633273_26	4792.ETI48143	1.848e-14	88.0	KOG4351@1|root,KOG4351@2759|Eukaryota,3Q8PI@4776|Peronosporales	4776|Peronosporales	S	Ig-like domain from next to BRCA1 gene	-	-	-	ko:K17987	ko04137,map04137	-	-	-	ko00000,ko00001,ko03029,ko04131	-	-	-	N_BRCA1_IG,PB1
WLSH2_k127_6633273_8	926569.ANT_22190	2.625e-83	307.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WLSH2_k127_6633273_6	1122182.KB903836_gene5006	9.036e-89	298.0	COG0745@1|root,COG0745@2|Bacteria,2H3IN@201174|Actinobacteria	201174|Actinobacteria	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_6633273_18	446469.Sked_02650	7.367e-47	183.0	COG0642@1|root,COG2205@2|Bacteria,2IIK0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WLSH2_k127_6633273_17	926569.ANT_29500	1.212e-53	195.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_6633273_7	324602.Caur_3746	1.577e-83	287.0	COG0412@1|root,COG0412@2|Bacteria,2G868@200795|Chloroflexi,37610@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
WLSH2_k127_6633273_16	765420.OSCT_1526	4.94e-56	203.0	COG2085@1|root,COG2085@2|Bacteria,2G900@200795|Chloroflexi,37616@32061|Chloroflexia	32061|Chloroflexia	C	NAD binding domain of 6-phosphogluconate dehydrogenase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
WLSH2_k127_6633273_14	1196322.A370_03935	2.067e-62	220.0	COG2128@1|root,COG2128@2|Bacteria,1V55P@1239|Firmicutes,24HT6@186801|Clostridia,36RNR@31979|Clostridiaceae	186801|Clostridia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WLSH2_k127_6633273_23	1227349.C170_19432	1.521e-30	134.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,26RKY@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_6633273_22	582899.Hden_0329	6.478e-41	164.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2TRYE@28211|Alphaproteobacteria,3N8BX@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055,ko:K19707	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Abhydrolase_1
WLSH2_k127_6633273_11	562970.Btus_0429	1.348e-73	259.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,4HAE2@91061|Bacilli,27893@186823|Alicyclobacillaceae	91061|Bacilli	C	Electron transfer flavoprotein FAD-binding domain	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WLSH2_k127_6633273_19	882082.SaccyDRAFT_3719	3.396e-45	173.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4E0JQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WLSH2_k127_6633273_9	383372.Rcas_1189	2.908e-81	277.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,2G6PS@200795|Chloroflexi,375KX@32061|Chloroflexia	32061|Chloroflexia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
WLSH2_k127_6633273_20	99598.Cal7507_5431	3.284e-44	164.0	COG2337@1|root,COG2337@2|Bacteria,1G7P3@1117|Cyanobacteria,1HPNZ@1161|Nostocales	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
WLSH2_k127_6633273_28	870187.Thini_2802	4.365e-11	66.0	COG0864@1|root,COG0864@2|Bacteria,1NJ2M@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6633273_5	1521187.JPIM01000016_gene3673	8.562e-107	352.0	COG3836@1|root,COG3836@2|Bacteria,2G925@200795|Chloroflexi,377KS@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.20,4.1.2.52	ko:K01630,ko:K02510	ko00053,ko00350,ko01120,map00053,map00350,map01120	-	R01645,R01647,R02754,R03277	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
WLSH2_k127_6633273_2	867845.KI911784_gene2927	7.526e-149	481.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,3759Q@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_6633273_0	926569.ANT_03530	0.0	1124.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH2_k127_6633273_15	452637.Oter_2875	2.746e-62	224.0	COG0672@1|root,COG0672@2|Bacteria,46XX5@74201|Verrucomicrobia,3K8IC@414999|Opitutae	414999|Opitutae	P	Iron permease FTR1 family	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
WLSH2_k127_6633273_3	926569.ANT_06860	4.515e-122	409.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi	200795|Chloroflexi	L	PFAM IstB domain protein ATP-binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
WLSH2_k127_6633273_24	485913.Krac_12129	2.052e-28	123.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
WLSH2_k127_6633273_1	56107.Cylst_0451	2.936e-186	592.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1G0R8@1117|Cyanobacteria,1HJAT@1161|Nostocales	1117|Cyanobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
WLSH2_k127_6633570_7	1040986.ATYO01000012_gene5293	9.799e-103	375.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYI3@28211|Alphaproteobacteria,43RTK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,PAS_9,Response_reg
WLSH2_k127_6633570_16	283942.IL0206	3.701e-38	167.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2QF28@267893|Idiomarinaceae	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GAF_2,GGDEF
WLSH2_k127_6633570_10	589924.Ferp_1746	1.369e-55	207.0	COG0407@1|root,arCOG03323@2157|Archaea,2XV21@28890|Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	2.1.1.246,2.1.1.247,4.1.1.37	ko:K01599,ko:K14080,ko:K14082	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356,M00563	R03197,R04972,R09098,R09124,R09998,R09999,R10000	RC00035,RC00556,RC00732,RC00872,RC01144,RC02440,RC02984,RC02985,RC02986	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WLSH2_k127_6633570_9	903818.KI912269_gene107	1.536e-64	231.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
WLSH2_k127_6633570_1	706587.Desti_0873	1.587e-199	643.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MQU1@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WLSH2_k127_6633570_20	452637.Oter_4337	1.097e-10	66.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	mtbC	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
WLSH2_k127_6633570_3	118161.KB235922_gene3038	3.297e-140	460.0	COG2081@1|root,COG2081@2|Bacteria,1FZZ1@1117|Cyanobacteria,3VIXX@52604|Pleurocapsales	1117|Cyanobacteria	S	flavoprotein, HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WLSH2_k127_6633570_22	667014.Thein_1743	0.000134	54.0	COG1807@1|root,COG1807@2|Bacteria,2GIEC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6633570_0	1499967.BAYZ01000089_gene5053	1.685e-259	819.0	COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria	2|Bacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
WLSH2_k127_6633570_4	357808.RoseRS_2814	1.063e-137	452.0	COG3669@1|root,COG3669@2|Bacteria,2G801@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 29 (alpha-L-fucosidase)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
WLSH2_k127_6633570_11	1122919.KB905555_gene936	3.852e-55	198.0	COG4154@1|root,COG4154@2|Bacteria,1V402@1239|Firmicutes,4HJRX@91061|Bacilli,26XPH@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the RbsD FucU family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
WLSH2_k127_6633570_2	694427.Palpr_2889	3.081e-145	469.0	COG0615@1|root,COG2605@1|root,COG0615@2|Bacteria,COG2605@2|Bacteria,4NGSD@976|Bacteroidetes,2FQ1X@200643|Bacteroidia,22WKK@171551|Porphyromonadaceae	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GHMP_kinases_C
WLSH2_k127_6633570_6	760568.Desku_3456	1.927e-123	407.0	COG3177@1|root,COG3177@2|Bacteria,1TV5J@1239|Firmicutes,24CRC@186801|Clostridia,2616P@186807|Peptococcaceae	186801|Clostridia	S	PFAM Fic DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_24,TrmB
WLSH2_k127_6633570_13	765420.OSCT_0136	2.368e-42	172.0	COG4924@1|root,COG4924@2|Bacteria,2GAPK@200795|Chloroflexi,376YN@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function C-terminus (DUF2399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
WLSH2_k127_6633570_5	1121430.JMLG01000002_gene1100	3.506e-131	459.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,2630X@186807|Peptococcaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
WLSH2_k127_6633570_17	760568.Desku_0320	2.871e-22	105.0	2A8HA@1|root,30XJD@2|Bacteria,1UPU3@1239|Firmicutes,25HP8@186801|Clostridia,26728@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
WLSH2_k127_6633570_14	264732.Moth_0488	7.624e-41	168.0	28JJB@1|root,2Z9CE@2|Bacteria,1U6BP@1239|Firmicutes,24B0T@186801|Clostridia,42GYQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6633570_23	1122947.FR7_2614	0.0001803	47.0	COG3655@1|root,COG3655@2|Bacteria,1VKVP@1239|Firmicutes	1239|Firmicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
WLSH2_k127_6633570_15	237368.SCABRO_01787	5.317e-40	149.0	COG2963@1|root,COG3335@1|root,COG2963@2|Bacteria,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_28,HTH_Tnp_1
WLSH2_k127_6633570_8	237368.SCABRO_01787	1.286e-69	240.0	COG2963@1|root,COG3335@1|root,COG2963@2|Bacteria,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_28,HTH_Tnp_1
WLSH2_k127_6633570_19	237368.SCABRO_01787	3.591e-14	80.0	COG2963@1|root,COG3335@1|root,COG2963@2|Bacteria,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_28,HTH_Tnp_1
WLSH2_k127_6633570_18	419947.MRA_2630	3.57e-21	98.0	COG1848@1|root,COG1848@2|Bacteria,2H8TE@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576,GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
WLSH2_k127_6633570_12	1521187.JPIM01000048_gene77	4.924e-51	190.0	COG3677@1|root,COG3677@2|Bacteria,2G6SJ@200795|Chloroflexi,3772U@32061|Chloroflexia	32061|Chloroflexia	L	PFAM Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6677138_0	768671.ThimaDRAFT_4426	1.326e-148	486.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria,1SQA0@1236|Gammaproteobacteria,1X16W@135613|Chromatiales	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6677138_1	485915.Dret_0923	2.962e-16	82.0	COG0697@1|root,COG0697@2|Bacteria,1Q9QV@1224|Proteobacteria,43293@68525|delta/epsilon subdivisions,2WXT3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6691072_8	56110.Oscil6304_1636	1.872e-06	49.0	COG3464@1|root,COG3464@2|Bacteria,1G25X@1117|Cyanobacteria,1HF3V@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_6691072_7	1121468.AUBR01000036_gene1308	7.062e-08	60.0	COG2203@1|root,COG3437@1|root,COG3605@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,COG4936@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42JGC@68295|Thermoanaerobacterales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,PocR,SBP_bac_3
WLSH2_k127_6691072_0	926569.ANT_08730	0.0	1084.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
WLSH2_k127_6691072_4	1298593.TOL_1973	4.427e-65	237.0	COG4221@1|root,COG4221@2|Bacteria,1QTXD@1224|Proteobacteria,1T1MG@1236|Gammaproteobacteria,1XRVJ@135619|Oceanospirillales	135619|Oceanospirillales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_6691072_1	926569.ANT_08710	9.01e-204	653.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WLSH2_k127_6691072_2	926569.ANT_09200	5.229e-173	558.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH2_k127_6691072_3	926569.ANT_08300	1.123e-86	287.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
WLSH2_k127_6691072_5	926569.ANT_08310	1.387e-48	178.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
WLSH2_k127_6695383_0	485913.Krac_7480	1.889e-120	428.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
WLSH2_k127_6695383_1	631362.Thi970DRAFT_00174	2.278e-08	55.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
WLSH2_k127_6707850_27	1170562.Cal6303_4868	6.747e-26	108.0	COG0765@1|root,COG0765@2|Bacteria,1GQ0J@1117|Cyanobacteria,1HK34@1161|Nostocales	1117|Cyanobacteria	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
WLSH2_k127_6707850_20	240292.Ava_0738	9.775e-85	299.0	COG0765@1|root,COG0765@2|Bacteria,1G2E3@1117|Cyanobacteria,1HJ18@1161|Nostocales	1117|Cyanobacteria	P	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
WLSH2_k127_6707850_12	357808.RoseRS_4002	3.336e-132	424.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,376F8@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K09972	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
WLSH2_k127_6707850_24	926569.ANT_15100	1.093e-57	201.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH2_k127_6707850_13	926569.ANT_16640	9.106e-127	411.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WLSH2_k127_6707850_8	926569.ANT_16650	1.214e-150	482.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH2_k127_6707850_17	204669.Acid345_0734	8.359e-114	388.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
WLSH2_k127_6707850_30	357808.RoseRS_1951	2.868e-14	83.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6707850_26	644966.Tmar_1220	4.629e-36	145.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia	186801|Clostridia	S	PFAM Rhomboid family	GlpG	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WLSH2_k127_6707850_23	926569.ANT_25400	3.482e-58	211.0	COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S1
WLSH2_k127_6707850_28	1121441.AUCX01000010_gene144	2.69e-22	102.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
WLSH2_k127_6707850_9	476272.RUMHYD_02346	1.452e-150	488.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_6707850_7	1121380.JNIW01000033_gene3726	1.503e-157	510.0	COG0161@1|root,COG0161@2|Bacteria,1WISD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
WLSH2_k127_6707850_0	211165.AJLN01000116_gene3197	3.727e-222	697.0	COG1012@1|root,COG1012@2|Bacteria,1G09W@1117|Cyanobacteria,1JHZW@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH2_k127_6707850_10	374847.Kcr_0325	7.637e-144	473.0	arCOG03462@1|root,arCOG03462@2157|Archaea	2157|Archaea	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_6707850_19	374847.Kcr_0805	6.73e-95	321.0	COG2129@1|root,arCOG01145@2157|Archaea	2157|Archaea	P	PFAM Metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_3
WLSH2_k127_6707850_21	374847.Kcr_0806	1.13e-69	245.0	arCOG06048@1|root,arCOG06048@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6707850_5	485913.Krac_7969	4.763e-163	526.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	patA	-	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K05830,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R01155,R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_6707850_14	926550.CLDAP_37530	2.757e-126	413.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
WLSH2_k127_6707850_16	926550.CLDAP_37540	1.928e-120	393.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
WLSH2_k127_6707850_18	926550.CLDAP_37550	2.708e-109	361.0	COG1177@1|root,COG1177@2|Bacteria,2G6DH@200795|Chloroflexi	200795|Chloroflexi	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
WLSH2_k127_6707850_6	926550.CLDAP_37560	1.607e-162	524.0	COG0687@1|root,COG0687@2|Bacteria,2G6U4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
WLSH2_k127_6707850_25	926550.CLDAP_37590	7.301e-44	164.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	asnC	-	-	ko:K03718,ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_AsnC-type
WLSH2_k127_6707850_4	1121422.AUMW01000006_gene704	4.103e-167	537.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,26029@186807|Peptococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WLSH2_k127_6707850_22	661478.OP10G_1682	1.007e-68	254.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_6707850_2	1121324.CLIT_8c01210	3.649e-176	572.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_6707850_11	926550.CLDAP_05420	2.963e-138	451.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_6707850_1	1118054.CAGW01000101_gene4724	7.08e-197	623.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HV0C@91061|Bacilli,271MY@186822|Paenibacillaceae	91061|Bacilli	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
WLSH2_k127_6707850_3	868595.Desca_2486	1.443e-173	562.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,2604P@186807|Peptococcaceae	186801|Clostridia	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_6707850_34	1120949.KB903297_gene5464	5.308e-10	65.0	COG2909@1|root,COG2909@2|Bacteria,2HWIY@201174|Actinobacteria,4DJ0G@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WLSH2_k127_6707850_32	880072.Desac_2172	2.485e-12	71.0	arCOG07300@1|root,2ZTGG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6707850_15	880072.Desac_2171	1.367e-122	424.0	COG0417@1|root,COG0417@2|Bacteria	2|Bacteria	L	DNA replication proofreading	polB	-	2.7.7.7	ko:K02336,ko:K06877	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	CarbopepD_reg_2,DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
WLSH2_k127_6707850_35	545697.HMPREF0216_01814	4.477e-08	57.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,36DBS@31979|Clostridiaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_6707850_31	926569.ANT_15130	3.004e-13	76.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
WLSH2_k127_6707850_33	1463854.JOHT01000012_gene4379	8.716e-12	68.0	COG0515@1|root,COG0515@2|Bacteria,2GNXG@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknJ	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,VCBS
WLSH2_k127_6707850_36	350054.Mflv_1389	5.201e-07	52.0	COG0515@1|root,COG0515@2|Bacteria,2H5ZS@201174|Actinobacteria,232IX@1762|Mycobacteriaceae	201174|Actinobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K08282,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WLSH2_k127_6707850_37	1469607.KK073768_gene1802	1.774e-06	59.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	I-set,ig
WLSH2_k127_6707850_29	497965.Cyan7822_6681	1.698e-18	89.0	COG1262@1|root,COG1262@2|Bacteria,1GMI4@1117|Cyanobacteria,3KKEX@43988|Cyanothece	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TIR_2
WLSH2_k127_6713053_27	926569.ANT_08330	3.463e-16	79.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WLSH2_k127_6713053_3	926569.ANT_08340	5.223e-199	627.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WLSH2_k127_6713053_0	926569.ANT_08350	1.742e-301	944.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WLSH2_k127_6713053_9	926569.ANT_08360	1.744e-127	421.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WLSH2_k127_6713053_16	926569.ANT_08370	1.586e-76	259.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
WLSH2_k127_6713053_20	926569.ANT_08380	8.664e-43	162.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WLSH2_k127_6713053_24	926569.ANT_08390	8.58e-33	129.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
WLSH2_k127_6713053_1	926569.ANT_08400	2.263e-219	702.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	200795|Chloroflexi	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
WLSH2_k127_6713053_2	926569.ANT_08410	2.657e-206	652.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WLSH2_k127_6713053_7	926569.ANT_08420	1.265e-156	507.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
WLSH2_k127_6713053_22	459495.SPLC1_S200360	1.646e-34	140.0	COG2199@1|root,COG3706@2|Bacteria,1G35Y@1117|Cyanobacteria,1H9VP@1150|Oscillatoriales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K21020	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Response_reg
WLSH2_k127_6713053_30	319795.Dgeo_2833	0.0001137	51.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,GGDEF,HD,HD_5,Response_reg,TPR_12
WLSH2_k127_6713053_32	1449976.KALB_471	0.000888	49.0	COG0457@1|root,COG0457@2|Bacteria,2INUN@201174|Actinobacteria,4EDSQ@85010|Pseudonocardiales	201174|Actinobacteria	S	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,NB-ARC,TPR_12,TPR_7,TPR_8
WLSH2_k127_6713053_31	313606.M23134_04413	0.0001576	49.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NUFW@976|Bacteroidetes,47TYP@768503|Cytophagia	976|Bacteroidetes	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE,TPR_12
WLSH2_k127_6713053_18	485913.Krac_2673	3.499e-50	186.0	COG0637@1|root,COG0637@2|Bacteria,2G8S9@200795|Chloroflexi	200795|Chloroflexi	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WLSH2_k127_6713053_10	1379698.RBG1_1C00001G1677	4.775e-118	388.0	COG3239@1|root,COG3239@2|Bacteria,2NNTZ@2323|unclassified Bacteria	2|Bacteria	I	Fatty acid desaturase	des	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
WLSH2_k127_6713053_29	1394178.AWOO02000068_gene265	1.14e-05	52.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
WLSH2_k127_6713053_23	1121904.ARBP01000002_gene7038	1.444e-33	143.0	2F621@1|root,33YKD@2|Bacteria,4P4GW@976|Bacteroidetes,47VGC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6713053_5	485913.Krac_4493	2.001e-165	539.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi	200795|Chloroflexi	L	COGs COG1961 Site-specific recombinase DNA invertase Pin homologs	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_6713053_4	1128421.JAGA01000002_gene791	4.922e-196	622.0	COG0477@1|root,COG0477@2|Bacteria,2NQG6@2323|unclassified Bacteria	2|Bacteria	EGP	Sugar (and other) transporter	bmr3_1	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_6713053_26	292459.STH1911	1.571e-18	100.0	2DTCK@1|root,33JQD@2|Bacteria,1VNW3@1239|Firmicutes,24X19@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6713053_14	1297569.MESS2_1220011	1.309e-79	276.0	COG1609@1|root,COG1609@2|Bacteria,1R5GE@1224|Proteobacteria,2UC92@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Rhodopirellula transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013
WLSH2_k127_6713053_25	926569.ANT_25960	1.743e-23	102.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WLSH2_k127_6713053_6	926569.ANT_25960	3.12e-165	524.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WLSH2_k127_6713053_8	926569.ANT_25980	9.113e-131	430.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
WLSH2_k127_6713053_17	102129.Lepto7375DRAFT_2355	1.1e-62	223.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
WLSH2_k127_6713053_15	1537915.JU57_10280	6.861e-79	272.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2YMQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WLSH2_k127_6713053_11	1499967.BAYZ01000028_gene1313	6.463e-98	329.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_6713053_12	1499967.BAYZ01000028_gene1314	6.758e-97	326.0	COG0573@1|root,COG0573@2|Bacteria,2NPS2@2323|unclassified Bacteria	2|Bacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_6713053_13	593750.Metfor_0423	3.262e-92	314.0	COG0226@1|root,arCOG00213@2157|Archaea,2XW2U@28890|Euryarchaeota	28890|Euryarchaeota	P	ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WLSH2_k127_6713053_21	497964.CfE428DRAFT_0276	9.954e-42	158.0	COG1959@1|root,COG1959@2|Bacteria,46SPI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WLSH2_k127_6756_6	485913.Krac_2258	1.986e-48	178.0	COG1662@1|root,COG1662@2|Bacteria	2|Bacteria	L	PFAM IS1 transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1
WLSH2_k127_6756_8	309807.SRU_0712	6.363e-27	112.0	COG3677@1|root,COG3677@2|Bacteria,4NP1W@976|Bacteroidetes	976|Bacteroidetes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,Terminase_5,Zn_Tnp_IS1
WLSH2_k127_6756_9	743719.PaelaDRAFT_0890	3.121e-08	62.0	COG1680@1|root,COG1680@2|Bacteria,1UZZ5@1239|Firmicutes,4HA1I@91061|Bacilli,26XEG@186822|Paenibacillaceae	91061|Bacilli	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
WLSH2_k127_6756_7	439235.Dalk_0029	3.023e-43	173.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WLSH2_k127_6756_5	358220.C380_01020	3.33e-74	267.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2W4ZW@28216|Betaproteobacteria	28216|Betaproteobacteria	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_6756_4	1502850.FG91_01894	1.698e-101	346.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria,2K947@204457|Sphingomonadales	204457|Sphingomonadales	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
WLSH2_k127_6756_0	1304885.AUEY01000021_gene3450	1.398e-181	585.0	COG0277@1|root,COG0277@2|Bacteria,1MXTV@1224|Proteobacteria,42RXR@68525|delta/epsilon subdivisions,2WNHV@28221|Deltaproteobacteria,2MK34@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
WLSH2_k127_6756_1	1223521.BBJX01000005_gene1942	7.552e-168	542.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VPTU@28216|Betaproteobacteria,4AEAX@80864|Comamonadaceae	28216|Betaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB2	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WLSH2_k127_6756_3	1408473.JHXO01000004_gene82	1.094e-132	433.0	COG0641@1|root,COG0641@2|Bacteria,4NG1N@976|Bacteroidetes,2FMBY@200643|Bacteroidia	976|Bacteroidetes	C	Anaerobic sulfatase maturase	atsB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WLSH2_k127_6756_2	644282.Deba_3012	2.038e-166	540.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
WLSH2_k127_6782431_5	926569.ANT_10160	1.233e-77	261.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi	200795|Chloroflexi	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
WLSH2_k127_6782431_15	926569.ANT_10170	1.044e-27	113.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi	200795|Chloroflexi	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
WLSH2_k127_6782431_9	926569.ANT_10180	1.899e-61	214.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
WLSH2_k127_6782431_7	926569.ANT_10190	7.265e-71	246.0	COG0097@1|root,COG0097@2|Bacteria,2G6HZ@200795|Chloroflexi	200795|Chloroflexi	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
WLSH2_k127_6782431_14	926569.ANT_10200	2.261e-42	158.0	COG0256@1|root,COG0256@2|Bacteria,2G6Y4@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
WLSH2_k127_6782431_6	926569.ANT_10210	1.926e-77	263.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi	200795|Chloroflexi	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
WLSH2_k127_6782431_16	485913.Krac_12510	1.023e-17	84.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
WLSH2_k127_6782431_12	926569.ANT_10230	3.271e-57	202.0	COG0200@1|root,COG0200@2|Bacteria,2G6XY@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
WLSH2_k127_6782431_1	926569.ANT_10240	1.823e-154	500.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi	200795|Chloroflexi	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WLSH2_k127_6782431_4	926569.ANT_10250	1.862e-80	273.0	COG0563@1|root,COG0563@2|Bacteria,2G6GP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WLSH2_k127_6782431_2	926569.ANT_10260	3.596e-106	350.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi	200795|Chloroflexi	J	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WLSH2_k127_6782431_17	926569.ANT_10270	2.491e-13	70.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WLSH2_k127_6782431_8	926569.ANT_10280	1.412e-61	213.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WLSH2_k127_6782431_10	926569.ANT_10290	2.108e-61	216.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WLSH2_k127_6782431_3	926569.ANT_10300	8.485e-91	302.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WLSH2_k127_6782431_0	926569.ANT_10310	1.029e-162	516.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WLSH2_k127_6782431_13	926569.ANT_10320	9.813e-51	183.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WLSH2_k127_6782431_11	926569.ANT_10330	5.566e-59	209.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WLSH2_k127_6792473_19	926569.ANT_26040	2.118e-10	67.0	COG5433@1|root,COG5433@2|Bacteria,2G91G@200795|Chloroflexi	200795|Chloroflexi	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
WLSH2_k127_6792473_15	926569.ANT_26050	1.162e-22	102.0	COG5433@1|root,COG5433@2|Bacteria,2G91M@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
WLSH2_k127_6792473_13	311424.DhcVS_1332	7.313e-27	112.0	COG2963@1|root,COG2963@2|Bacteria,2GAW0@200795|Chloroflexi,34DGC@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
WLSH2_k127_6792473_4	311424.DhcVS_776	1.53e-112	373.0	COG2801@1|root,COG2801@2|Bacteria,2G8GQ@200795|Chloroflexi,34DDP@301297|Dehalococcoidia	301297|Dehalococcoidia	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
WLSH2_k127_6792473_20	641491.DND132_0991	4.052e-09	59.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MB6B@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
WLSH2_k127_6792473_6	926550.CLDAP_25650	1.498e-102	341.0	COG2267@1|root,COG2267@2|Bacteria,2G6DZ@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_6792473_8	537013.CLOSTMETH_00060	9.139e-81	280.0	2F5DW@1|root,33XZS@2|Bacteria,1UT5H@1239|Firmicutes,251FX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6792473_0	926569.ANT_31720	3.614e-306	944.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
WLSH2_k127_6792473_7	1123320.KB889562_gene6566	1.303e-84	286.0	COG0745@1|root,COG0745@2|Bacteria,2H3IN@201174|Actinobacteria	201174|Actinobacteria	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_6792473_10	1123320.KB889562_gene6565	9.478e-53	204.0	COG0642@1|root,COG2205@2|Bacteria,2IIK0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WLSH2_k127_6792473_12	515620.EUBELI_01878	3.256e-27	113.0	COG1695@1|root,COG1695@2|Bacteria,1V85H@1239|Firmicutes,24N2G@186801|Clostridia,25ZGS@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WLSH2_k127_6792473_17	1145276.T479_23345	1.375e-12	79.0	COG0604@1|root,COG0604@2|Bacteria,1TT5J@1239|Firmicutes,4HCXG@91061|Bacilli,3IWSQ@400634|Lysinibacillus	91061|Bacilli	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6792473_18	926569.ANT_08800	1.942e-11	69.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4082,DUF5011,SLH
WLSH2_k127_6792473_5	926569.ANT_23120	2.334e-103	344.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
WLSH2_k127_6792473_3	926550.CLDAP_34690	1.33e-131	428.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WLSH2_k127_6792473_16	266940.Krad_2256	2.521e-18	91.0	COG0454@1|root,COG0456@2|Bacteria,2H0M6@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_6792473_1	926550.CLDAP_20840	3.709e-304	941.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
WLSH2_k127_6792473_2	1123274.KB899433_gene1351	5.885e-236	743.0	COG0441@1|root,COG0441@2|Bacteria,2J5ID@203691|Spirochaetes	203691|Spirochaetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
WLSH2_k127_6792473_9	926569.ANT_02480	5.977e-73	253.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WLSH2_k127_6792473_14	926569.ANT_00600	3.824e-23	100.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WLSH2_k127_6792473_11	926569.ANT_00590	1.625e-46	169.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WLSH2_k127_6800631_0	926569.ANT_03460	7.156e-257	805.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH2_k127_6800631_1	926569.ANT_24700	2.01e-140	454.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi	200795|Chloroflexi	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WLSH2_k127_6800631_2	357808.RoseRS_0185	8.208e-35	137.0	COG1848@1|root,COG1848@2|Bacteria,2G94W@200795|Chloroflexi,377TP@32061|Chloroflexia	32061|Chloroflexia	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_6930815_3	443144.GM21_0294	1.906e-40	151.0	COG4679@1|root,COG4679@2|Bacteria,1MZ3N@1224|Proteobacteria,42TST@68525|delta/epsilon subdivisions,2WX5S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
WLSH2_k127_6930815_1	1173024.KI912152_gene425	3.297e-105	360.0	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_6930815_4	876269.ARWA01000001_gene3722	2.274e-14	78.0	COG1366@1|root,COG1366@2|Bacteria,1NECY@1224|Proteobacteria,2UHIF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
WLSH2_k127_6930815_0	357808.RoseRS_4157	4.417e-112	372.0	COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like,PBP_like_2
WLSH2_k127_6930815_2	383372.Rcas_0588	3.121e-58	207.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi,375B0@32061|Chloroflexia	32061|Chloroflexia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_6946469_2	485913.Krac_12092	5.941e-248	775.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH2_k127_6946469_17	926550.CLDAP_21600	1.477e-93	318.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_6946469_12	574376.BAMA_01525	2.796e-136	444.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus	91061|Bacilli	I	acyl-CoA dehydrogenase	acdA	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_6946469_51	266117.Rxyl_0497	8.233e-07	60.0	COG3296@1|root,COG3296@2|Bacteria,2GXDT@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
WLSH2_k127_6946469_24	525904.Tter_0351	1.424e-58	214.0	COG2362@1|root,COG2362@2|Bacteria,2NPDW@2323|unclassified Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
WLSH2_k127_6946469_6	926550.CLDAP_19310	1.628e-181	576.0	COG0687@1|root,COG0687@2|Bacteria	2|Bacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	ydcS	GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	iECNA114_1301.ECNA114_1576,iECSF_1327.ECSF_1364,iEcHS_1320.EcHS_A1524	SBP_bac_8
WLSH2_k127_6946469_11	926550.CLDAP_19330	3.296e-139	452.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	ydcT	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
WLSH2_k127_6946469_15	926550.CLDAP_19340	8.788e-119	389.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
WLSH2_k127_6946469_16	1408224.SAMCCGM7_c4618	1.24e-113	372.0	COG1177@1|root,COG1177@2|Bacteria,1N3TB@1224|Proteobacteria,2U23R@28211|Alphaproteobacteria,4B8ND@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter permease	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
WLSH2_k127_6946469_25	926569.ANT_22220	3.993e-56	204.0	COG2940@1|root,COG2940@2|Bacteria,2G9DE@200795|Chloroflexi	200795|Chloroflexi	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
WLSH2_k127_6946469_45	667014.Thein_1743	1.149e-11	78.0	COG1807@1|root,COG1807@2|Bacteria,2GIEC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6946469_18	357808.RoseRS_3747	2.935e-87	292.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_6946469_43	1082933.MEA186_23816	1.723e-14	79.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.1.1.137,2.3.1.1	ko:K00537,ko:K00619,ko:K07755	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
WLSH2_k127_6946469_35	246194.CHY_0402	4.394e-35	141.0	COG1555@1|root,COG1596@1|root,COG1555@2|Bacteria,COG1596@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,42GSI@68295|Thermoanaerobacterales	186801|Clostridia	LM	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
WLSH2_k127_6946469_28	926569.ANT_01640	1.733e-51	187.0	COG0500@1|root,COG2226@2|Bacteria,2G8IN@200795|Chloroflexi	200795|Chloroflexi	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
WLSH2_k127_6946469_13	1480694.DC28_04730	1.079e-126	420.0	COG2211@1|root,COG2211@2|Bacteria,2J6P4@203691|Spirochaetes	203691|Spirochaetes	G	transporter	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WLSH2_k127_6946469_36	266117.Rxyl_2580	6.67e-34	143.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WLSH2_k127_6946469_23	1321778.HMPREF1982_01435	1.084e-62	231.0	COG0477@1|root,COG2814@2|Bacteria,1VB8Y@1239|Firmicutes,24KIW@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_6946469_31	926569.ANT_10650	5.493e-44	166.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,TPMT
WLSH2_k127_6946469_1	926569.ANT_14030	1.742e-300	935.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH2_k127_6946469_55	591159.ACEZ01000121_gene455	0.0003383	53.0	COG1349@1|root,COG1349@2|Bacteria,2GKWM@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator (DeoR family)	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
WLSH2_k127_6946469_48	926550.CLDAP_00490	3.471e-09	62.0	COG1977@1|root,COG1977@2|Bacteria,2G74G@200795|Chloroflexi	200795|Chloroflexi	H	PFAM thiamineS protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH2_k127_6946469_8	518766.Rmar_1680	1.561e-148	480.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	HP	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
WLSH2_k127_6946469_7	1128421.JAGA01000004_gene2611	2.542e-150	489.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
WLSH2_k127_6946469_0	926569.ANT_14230	0.0	1378.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_6946469_37	926569.ANT_14220	8.316e-32	129.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_14220|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6946469_26	926569.ANT_14190	1.342e-54	201.0	COG2267@1|root,COG2267@2|Bacteria,2GBHH@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_6946469_32	478741.JAFS01000002_gene159	2.743e-42	161.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia,37GNT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	RNase_H superfamily	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	RNase_H_2
WLSH2_k127_6946469_14	926569.ANT_14180	9.664e-123	410.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WLSH2_k127_6946469_21	926569.ANT_14170	5.216e-78	264.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WLSH2_k127_6946469_19	926569.ANT_14160	3.375e-83	282.0	COG1435@1|root,COG1435@2|Bacteria,2G6DP@200795|Chloroflexi	200795|Chloroflexi	F	PFAM thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WLSH2_k127_6946469_27	926569.ANT_25140	5.715e-53	191.0	COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi	200795|Chloroflexi	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WLSH2_k127_6946469_34	926569.ANT_25130	5.823e-36	139.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WLSH2_k127_6946469_38	926569.ANT_25120	2.149e-30	126.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi	200795|Chloroflexi	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WLSH2_k127_6946469_39	1459636.NTE_00040	2.464e-30	135.0	arCOG09466@1|root,arCOG09466@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6946469_3	926569.ANT_19800	3.167e-216	694.0	COG0210@1|root,COG0210@2|Bacteria,2G7VU@200795|Chloroflexi	200795|Chloroflexi	F	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6946469_46	395961.Cyan7425_4264	1.558e-10	72.0	COG5361@1|root,COG5361@2|Bacteria,1G8PW@1117|Cyanobacteria,3KHNR@43988|Cyanothece	1117|Cyanobacteria	S	Neurotransmitter-gated ion-channel ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Neur_chan_LBD,Neur_chan_memb
WLSH2_k127_6946469_42	373994.Riv7116_6515	1.653e-16	81.0	COG2161@1|root,COG2161@2|Bacteria,1GA1V@1117|Cyanobacteria	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WLSH2_k127_6946469_30	373994.Riv7116_6516	2.745e-45	168.0	COG1487@1|root,COG1487@2|Bacteria,1G63I@1117|Cyanobacteria,1HPWQ@1161|Nostocales	1117|Cyanobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
WLSH2_k127_6946469_50	1453498.LG45_13495	1.917e-07	56.0	COG0614@1|root,COG0614@2|Bacteria,4NQQ6@976|Bacteroidetes,1I4E1@117743|Flavobacteriia,2NWPM@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH2_k127_6946469_44	247490.KSU1_D0778	3.501e-13	72.0	COG0614@1|root,COG0614@2|Bacteria,2J06G@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH2_k127_6946469_4	926569.ANT_19790	1.644e-197	642.0	COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi	200795|Chloroflexi	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH2_k127_6946469_54	933115.GPDM_15084	0.0003135	50.0	COG1112@1|root,COG2852@1|root,COG1112@2|Bacteria,COG2852@2|Bacteria,1TP20@1239|Firmicutes,4HDDW@91061|Bacilli	91061|Bacilli	L	Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726,DUF3320,DUF4011,DUF559
WLSH2_k127_6946469_29	485913.Krac_6390	1.404e-47	174.0	COG3945@1|root,COG3945@2|Bacteria,2G96X@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WLSH2_k127_6946469_53	1123501.KB902287_gene2005	0.0001959	47.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0337 (CsbD) family	yjbJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CsbD
WLSH2_k127_6946469_52	1123234.AUKI01000016_gene3047	8.248e-06	57.0	COG1988@1|root,COG1988@2|Bacteria,4NFBT@976|Bacteroidetes,1HY38@117743|Flavobacteriia	976|Bacteroidetes	S	membrane-bound metal-dependent	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
WLSH2_k127_6946469_33	1121272.KB903249_gene2255	2.546e-38	149.0	COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_6946469_49	633147.Olsu_1450	8.257e-08	58.0	COG1366@1|root,COG1366@2|Bacteria,2HPDI@201174|Actinobacteria,4CW8I@84998|Coriobacteriia	84998|Coriobacteriia	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS_2
WLSH2_k127_6946469_47	397288.C806_00570	7.859e-10	65.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24NE7@186801|Clostridia,27NXD@186928|unclassified Lachnospiraceae	186801|Clostridia	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
WLSH2_k127_6946469_40	1173028.ANKO01000243_gene4219	8.927e-20	97.0	COG0546@1|root,COG0546@2|Bacteria,1G52P@1117|Cyanobacteria,1HB0I@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Haloacid dehalogenase-like hydrolase	cbbZp	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WLSH2_k127_6946469_20	1345697.M493_15880	3.556e-82	295.0	COG2272@1|root,COG2272@2|Bacteria,1UXY5@1239|Firmicutes,4HCKV@91061|Bacilli,1WEY8@129337|Geobacillus	91061|Bacilli	I	Carboxylesterase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
WLSH2_k127_6946469_5	926569.ANT_11210	1.147e-189	605.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
WLSH2_k127_6946469_41	885272.JonanDRAFT_1018	1.171e-19	100.0	COG4942@1|root,COG4942@2|Bacteria,3T9S7@508458|Synergistetes	508458|Synergistetes	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
WLSH2_k127_6946469_22	926569.ANT_11190	2.666e-65	243.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
WLSH2_k127_6946469_10	1265505.ATUG01000001_gene3075	2.126e-145	470.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_6946469_9	383372.Rcas_3164	1.597e-147	482.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi,374W1@32061|Chloroflexia	32061|Chloroflexia	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WLSH2_k127_7030740_2	743719.PaelaDRAFT_2983	1.438e-29	120.0	COG0667@1|root,COG0667@2|Bacteria,1UKPC@1239|Firmicutes,4HCF8@91061|Bacilli,26VRP@186822|Paenibacillaceae	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_7030740_1	1131730.BAVI_09396	1.534e-86	299.0	COG3594@1|root,COG3594@2|Bacteria	2|Bacteria	G	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WLSH2_k127_7030740_0	1480694.DC28_05675	2.947e-90	308.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_7030740_3	521097.Coch_1240	2.348e-20	95.0	2DPPJ@1|root,332WE@2|Bacteria,4NV6D@976|Bacteroidetes,1IFHF@117743|Flavobacteriia,1ET18@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7052044_0	926569.ANT_10870	2.976e-276	869.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH2_k127_7052044_1	926569.ANT_18580	1.086e-07	63.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
WLSH2_k127_7062214_1	880073.Calab_3769	4.855e-67	231.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WLSH2_k127_7062214_0	1173024.KI912152_gene425	1.214e-105	361.0	COG5659@1|root,COG5659@2|Bacteria,1GDXT@1117|Cyanobacteria	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_7062214_2	1469607.KK073768_gene1009	6.427e-33	133.0	COG3039@1|root,COG3039@2|Bacteria,1G3YX@1117|Cyanobacteria	1117|Cyanobacteria	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
WLSH2_k127_7063984_2	926569.ANT_15410	3.398e-225	711.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
WLSH2_k127_7063984_18	1096769.Pelub83DRAFT_0631	1.606e-59	210.0	2E747@1|root,331NN@2|Bacteria,1N990@1224|Proteobacteria,2URBT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7063984_24	304371.MCP_1011	1.23e-28	124.0	COG0491@1|root,arCOG00504@2157|Archaea,2XWX3@28890|Euryarchaeota,2NAZE@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH2_k127_7063984_15	398579.Spea_3275	1.271e-74	274.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
WLSH2_k127_7063984_13	338969.Rfer_0357	1.548e-82	275.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,4ABCM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
WLSH2_k127_7063984_4	338969.Rfer_0358	4.671e-172	549.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_7063984_11	1303518.CCALI_01252	1.821e-88	307.0	COG2203@1|root,COG3437@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HD,HD_5,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WLSH2_k127_7063984_32	868131.MSWAN_2196	1.477e-09	70.0	COG0392@1|root,arCOG00899@2157|Archaea,2XTI1@28890|Euryarchaeota,23NKG@183925|Methanobacteria	183925|Methanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH2_k127_7063984_16	264732.Moth_0453	1.564e-74	275.0	COG0463@1|root,COG2120@1|root,COG0463@2|Bacteria,COG2120@2|Bacteria,1TQM2@1239|Firmicutes,24EYU@186801|Clostridia,42GI0@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PIG-L
WLSH2_k127_7063984_31	706587.Desti_5608	3.113e-16	83.0	COG3255@1|root,COG3255@2|Bacteria,1PWYZ@1224|Proteobacteria,432A7@68525|delta/epsilon subdivisions,2WXR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
WLSH2_k127_7063984_5	1125863.JAFN01000001_gene832	1.866e-151	488.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42M0D@68525|delta/epsilon subdivisions,2WK8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_7063984_0	316274.Haur_4394	1.593e-248	790.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
WLSH2_k127_7063984_6	357808.RoseRS_2971	1.13e-145	473.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi,3763W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_7063984_9	357808.RoseRS_2972	3.124e-128	421.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_7063984_20	316274.Haur_3168	7.116e-54	203.0	COG0491@1|root,COG0491@2|Bacteria,2GAIA@200795|Chloroflexi,376BC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH2_k127_7063984_22	562970.Btus_0118	2.512e-33	135.0	COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,4IQ6R@91061|Bacilli,27AQ7@186823|Alicyclobacillaceae	91061|Bacilli	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WLSH2_k127_7063984_25	926569.ANT_20480	2.248e-27	116.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7063984_27	926569.ANT_20470	1.462e-25	110.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
WLSH2_k127_7063984_21	1128421.JAGA01000002_gene1700	8.014e-37	148.0	COG0500@1|root,COG2226@2|Bacteria,2NRJA@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
WLSH2_k127_7063984_19	709986.Deima_1278	4.165e-58	208.0	COG1272@1|root,COG1272@2|Bacteria,1WK6W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
WLSH2_k127_7063984_29	1123248.KB893337_gene2566	3.889e-19	88.0	COG5470@1|root,COG5470@2|Bacteria,4NUEC@976|Bacteroidetes,1IZ1F@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
WLSH2_k127_7063984_3	1521187.JPIM01000063_gene2480	2.983e-211	677.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WLSH2_k127_7063984_33	1151117.AJLF01000001_gene954	5.358e-07	58.0	COG2306@1|root,arCOG05760@2157|Archaea,2XX0W@28890|Euryarchaeota,243ZF@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF402)	-	-	-	ko:K09145	-	-	-	-	ko00000	-	-	-	DUF402
WLSH2_k127_7063984_14	1033810.HLPCO_000691	3.185e-81	287.0	COG4188@1|root,COG4188@2|Bacteria,2NRT2@2323|unclassified Bacteria	2|Bacteria	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1400,PAF-AH_p_II
WLSH2_k127_7063984_17	215803.DB30_7007	7.784e-60	218.0	COG1181@1|root,COG2940@1|root,COG1181@2|Bacteria,COG2940@2|Bacteria,1Q3H4@1224|Proteobacteria,4399M@68525|delta/epsilon subdivisions,2X4H1@28221|Deltaproteobacteria,2YZ01@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WLSH2_k127_7063984_12	926550.CLDAP_26730	3.599e-85	287.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WLSH2_k127_7063984_26	646529.Desaci_0681	1.367e-25	113.0	COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes	1239|Firmicutes	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
WLSH2_k127_7063984_7	357808.RoseRS_4512	1.002e-140	454.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
WLSH2_k127_7063984_8	357808.RoseRS_4511	2.945e-131	423.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
WLSH2_k127_7063984_1	357808.RoseRS_4510	2.366e-234	732.0	COG0370@1|root,COG0370@2|Bacteria,2GBTA@200795|Chloroflexi,37667@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
WLSH2_k127_7063984_10	290317.Cpha266_1585	6.101e-108	358.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	DUF1735,Laminin_G_3,Patatin
WLSH2_k127_7063984_23	1198452.Jab_1c01130	6.137e-33	132.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WLSH2_k127_707395_1	515635.Dtur_1285	1.721e-51	200.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M8,Peptidase_S8,SLH
WLSH2_k127_707395_3	1168034.FH5T_11765	8.71e-22	102.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25,HTH_3
WLSH2_k127_707395_2	643867.Ftrac_1100	7.997e-35	144.0	COG1266@1|root,COG1266@2|Bacteria,4P725@976|Bacteroidetes	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WLSH2_k127_707395_0	29306.JOBE01000012_gene6482	1.833e-127	431.0	COG1680@1|root,COG4412@1|root,COG1680@2|Bacteria,COG4412@2|Bacteria,2I8QH@201174|Actinobacteria	201174|Actinobacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Peptidase_M6
WLSH2_k127_7074387_27	926550.CLDAP_09570	3.081e-57	207.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2G86V@200795|Chloroflexi	200795|Chloroflexi	KLT	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
WLSH2_k127_7074387_41	479432.Sros_6920	7.153e-28	126.0	COG4995@1|root,COG4995@2|Bacteria,2IJMG@201174|Actinobacteria,4EN7G@85012|Streptosporangiales	201174|Actinobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
WLSH2_k127_7074387_30	926550.CLDAP_09590	7.445e-41	166.0	COG1262@1|root,COG4995@1|root,COG1262@2|Bacteria,COG4995@2|Bacteria,2G903@200795|Chloroflexi	200795|Chloroflexi	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
WLSH2_k127_7074387_31	41431.PCC8801_2272	7.13e-39	160.0	COG2815@1|root,COG4249@1|root,COG2815@2|Bacteria,COG4249@2|Bacteria,1GAQE@1117|Cyanobacteria	1117|Cyanobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
WLSH2_k127_7074387_23	272134.KB731324_gene5924	6.987e-74	281.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,PD40,SpoIIE,TIR_2,WD40
WLSH2_k127_7074387_44	1307761.L21SP2_3412	7.197e-26	117.0	COG0204@1|root,COG2246@1|root,COG0204@2|Bacteria,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	cmk	-	2.3.1.51,2.4.1.83	ko:K00655,ko:K00721	ko00510,ko00561,ko00564,ko01100,ko01110,map00510,map00561,map00564,map01100,map01110	M00089	R01009,R02241,R09381	RC00004,RC00005,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01004	-	GT2	-	Acyltransferase,Glycos_transf_2,GtrA,Transglut_core
WLSH2_k127_7074387_22	459349.CLOAM1538	7.872e-76	271.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WLSH2_k127_7074387_26	221288.JH992901_gene4311	6.145e-71	248.0	COG2227@1|root,COG2227@2|Bacteria,1GQZP@1117|Cyanobacteria,1JKUR@1189|Stigonemataceae	1117|Cyanobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_7074387_24	1382356.JQMP01000003_gene2108	9.57e-73	264.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
WLSH2_k127_7074387_12	926569.ANT_15750	2.536e-121	403.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WLSH2_k127_7074387_25	926550.CLDAP_34250	2.745e-72	257.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
WLSH2_k127_7074387_19	858215.Thexy_1993	1.342e-79	302.0	COG0737@1|root,COG3103@1|root,COG0737@2|Bacteria,COG3103@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,42F9N@68295|Thermoanaerobacterales	186801|Clostridia	F	5'-nucleotidase	-	-	3.1.3.5,3.1.3.6,3.1.4.16	ko:K01081,ko:K01119	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos,SH3_3,SLH
WLSH2_k127_7074387_17	926569.ANT_17320	3.101e-88	300.0	29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7074387_13	324602.Caur_3302	1.357e-118	389.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,377SH@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
WLSH2_k127_7074387_46	269799.Gmet_0679	1.224e-15	91.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria,43TFZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
WLSH2_k127_7074387_45	926560.KE387023_gene1958	3.137e-21	101.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7074387_50	929562.Emtol_3724	1.645e-07	62.0	2AX7X@1|root,31P6Q@2|Bacteria,4NGGX@976|Bacteroidetes,47YE8@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7074387_39	383372.Rcas_0430	1.089e-29	126.0	2E64T@1|root,330TJ@2|Bacteria,2G93I@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7074387_51	706587.Desti_0439	1.358e-06	56.0	COG0664@1|root,COG0664@2|Bacteria,1NAYS@1224|Proteobacteria,42W1E@68525|delta/epsilon subdivisions,2WS96@28221|Deltaproteobacteria,2MS9T@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Cyclic nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WLSH2_k127_7074387_37	357808.RoseRS_0325	2.283e-30	128.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_7074387_28	926550.CLDAP_23690	9.81e-50	183.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WLSH2_k127_7074387_4	926569.ANT_12080	2.491e-173	556.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
WLSH2_k127_7074387_5	926569.ANT_12100	8.191e-157	511.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
WLSH2_k127_7074387_8	926569.ANT_12110	4.474e-134	444.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	2.7.7.6	ko:K03046,ko:K03641,ko:K08642	ko00230,ko00240,ko01100,ko02024,ko03020,map00230,map00240,map01100,map02024,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021,ko03400	2.C.1.2	-	-	Glyco_hydro_18,LysM,OapA,PD40,Peptidase_M23
WLSH2_k127_7074387_34	525244.HMPREF0023_1761	3.678e-34	136.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,1S6HB@1236|Gammaproteobacteria,3NNMS@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_7074387_21	926569.ANT_02710	1.01e-77	268.0	COG1526@1|root,COG1526@2|Bacteria,2G74E@200795|Chloroflexi	200795|Chloroflexi	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
WLSH2_k127_7074387_43	68194.JNXR01000007_gene4064	4.469e-26	118.0	COG2306@1|root,COG2306@2|Bacteria,2GJP9@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF402)	-	-	-	ko:K09145	-	-	-	-	ko00000	-	-	-	DUF402
WLSH2_k127_7074387_3	357808.RoseRS_3310	4.917e-219	694.0	COG0366@1|root,COG0366@2|Bacteria,2G7K6@200795|Chloroflexi,374W8@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
WLSH2_k127_7074387_47	509635.N824_29445	4.734e-13	73.0	COG4892@1|root,COG4892@2|Bacteria,4NSAM@976|Bacteroidetes,1ITM0@117747|Sphingobacteriia	976|Bacteroidetes	S	Cytochrome b5-like Heme Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
WLSH2_k127_7074387_32	457396.CSBG_03362	1.901e-38	153.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,36FZK@31979|Clostridiaceae	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
WLSH2_k127_7074387_16	316274.Haur_2706	3.168e-89	301.0	COG0861@1|root,COG0861@2|Bacteria,2GACS@200795|Chloroflexi,376V3@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
WLSH2_k127_7074387_36	401526.TcarDRAFT_0221	1.596e-31	136.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4H4EK@909932|Negativicutes	909932|Negativicutes	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH2_k127_7074387_1	926569.ANT_25420	2.98e-230	717.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WLSH2_k127_7074387_11	1128421.JAGA01000001_gene2435	3.493e-122	402.0	COG1814@1|root,COG1814@2|Bacteria,2NPJP@2323|unclassified Bacteria	2|Bacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
WLSH2_k127_7074387_48	63737.Npun_F6455	7.994e-09	61.0	COG4691@1|root,COG4691@2|Bacteria,1GA88@1117|Cyanobacteria,1HPB7@1161|Nostocales	1117|Cyanobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	RHH_5
WLSH2_k127_7074387_40	195250.CM001776_gene3460	1.668e-28	119.0	COG4113@1|root,COG4113@2|Bacteria,1G71V@1117|Cyanobacteria,1H20M@1129|Synechococcus	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_7074387_7	768671.ThimaDRAFT_1778	1.558e-135	439.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1X0CX@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.25	ko:K17950	ko00270,map00270	-	R07634	RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
WLSH2_k127_7074387_9	926569.ANT_22600	2.699e-129	423.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WLSH2_k127_7074387_35	1379698.RBG1_1C00001G0634	2.51e-32	134.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
WLSH2_k127_7074387_14	926569.ANT_22610	9.614e-116	382.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WLSH2_k127_7074387_0	926569.ANT_22620	1.383e-237	749.0	COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi	200795|Chloroflexi	GM	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
WLSH2_k127_7074387_20	246194.CHY_1057	9.603e-79	274.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,42JFW@68295|Thermoanaerobacterales	186801|Clostridia	M	RmlD substrate binding domain	-	-	4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7	ko:K01784,ko:K02473,ko:K03274,ko:K08678	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R00418,R01384,R02984,R05176	RC00289,RC00508,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,GDP_Man_Dehyd
WLSH2_k127_7074387_6	926569.ANT_22630	2.316e-141	465.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G6DJ@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WLSH2_k127_7074387_10	926569.ANT_22640	1.012e-122	401.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wblJ	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
WLSH2_k127_7074387_15	926569.ANT_22650	1.284e-92	320.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_7074387_52	1122247.C731_2463	0.0001753	53.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,233QA@1762|Mycobacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7074387_18	926569.ANT_22660	1.087e-87	294.0	COG0745@1|root,COG0745@2|Bacteria,2G8CC@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_7074387_29	479434.Sthe_1579	1.822e-43	162.0	COG0251@1|root,COG0251@2|Bacteria,2G6XT@200795|Chloroflexi,27YDZ@189775|Thermomicrobia	189775|Thermomicrobia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WLSH2_k127_7074387_2	926569.ANT_27450	4.292e-225	736.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,SpoIIE
WLSH2_k127_7074387_38	1128421.JAGA01000001_gene2037	8.777e-30	123.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2NRQE@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
WLSH2_k127_7074387_33	926569.ANT_27430	1.142e-35	141.0	COG1366@1|root,COG1366@2|Bacteria,2G9DJ@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
WLSH2_k127_7074387_42	42256.RradSPS_1835	1.111e-26	122.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRIR@84995|Rubrobacteria	84995|Rubrobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
WLSH2_k127_7132_5	358823.DF19_31705	4.126e-14	83.0	COG1522@1|root,COG1522@2|Bacteria,2GKP4@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
WLSH2_k127_7132_1	926569.ANT_17670	3.134e-67	233.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH2_k127_7132_3	177437.HRM2_08650	1.495e-26	112.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,42U95@68525|delta/epsilon subdivisions,2WQWB@28221|Deltaproteobacteria,2MNQA@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphomethylpyrimidine kinase	-	-	2.7.1.11	ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WLSH2_k127_7132_0	1454007.JAUG01000004_gene2697	2.456e-68	247.0	COG1373@1|root,COG1373@2|Bacteria,4NZYR@976|Bacteroidetes,1IW10@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_7132_2	1140.Synpcc7942_0532	1.376e-28	118.0	COG4634@1|root,COG4634@2|Bacteria,1G7JV@1117|Cyanobacteria	1117|Cyanobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
WLSH2_k127_7132_4	459495.SPLC1_S540170	4.209e-23	100.0	COG2442@1|root,COG2442@2|Bacteria,1G8BN@1117|Cyanobacteria,1HCH9@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WLSH2_k127_7167728_19	1379698.RBG1_1C00001G0051	4.9e-26	110.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
WLSH2_k127_7167728_18	452637.Oter_3675	6.916e-30	125.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
WLSH2_k127_7167728_22	644282.Deba_1750	3.71e-11	69.0	COG0745@1|root,COG0745@2|Bacteria,1RINR@1224|Proteobacteria,42T1R@68525|delta/epsilon subdivisions,2WPHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH2_k127_7167728_12	644282.Deba_1749	4.695e-62	228.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
WLSH2_k127_7167728_3	316067.Geob_1632	3.631e-134	451.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
WLSH2_k127_7167728_1	882083.SacmaDRAFT_1933	8.877e-184	596.0	COG0247@1|root,COG0247@2|Bacteria,2GJ7M@201174|Actinobacteria,4DYWI@85010|Pseudonocardiales	201174|Actinobacteria	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
WLSH2_k127_7167728_9	309801.trd_0148	1.673e-73	258.0	COG2025@1|root,COG2025@2|Bacteria,2G6PP@200795|Chloroflexi,27XU4@189775|Thermomicrobia	189775|Thermomicrobia	C	Electron transfer flavoprotein	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WLSH2_k127_7167728_14	309801.trd_0149	7.547e-54	199.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	iAF987.Gmet_2266	CCG,ETF,Fer4_8
WLSH2_k127_7167728_4	562970.Btus_2494	3.752e-124	409.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,4HB2J@91061|Bacilli,277YN@186823|Alicyclobacillaceae	91061|Bacilli	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
WLSH2_k127_7167728_11	485913.Krac_6669	4.141e-62	221.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_7167728_17	1382306.JNIM01000001_gene1046	2.789e-38	161.0	COG4585@1|root,COG4585@2|Bacteria,2G6F0@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
WLSH2_k127_7167728_6	926569.ANT_26970	1.153e-92	320.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
WLSH2_k127_7167728_5	926569.ANT_26980	3.245e-113	378.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
WLSH2_k127_7167728_16	926569.ANT_26970	1.026e-47	180.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
WLSH2_k127_7167728_7	290397.Adeh_2002	4.201e-83	288.0	COG3005@1|root,COG3005@2|Bacteria,1QYG3@1224|Proteobacteria,43CC8@68525|delta/epsilon subdivisions,2X7N4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
WLSH2_k127_7167728_10	485915.Dret_0273	1.262e-67	246.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42N47@68525|delta/epsilon subdivisions,2WIKZ@28221|Deltaproteobacteria,2M8JX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	qrcD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
WLSH2_k127_7167728_13	589924.Ferp_0123	1.127e-55	205.0	COG0437@1|root,arCOG01500@2157|Archaea,2XU83@28890|Euryarchaeota,246KB@183980|Archaeoglobi	183980|Archaeoglobi	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
WLSH2_k127_7167728_23	555088.DealDRAFT_0324	3.804e-11	74.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
WLSH2_k127_7167728_2	926569.ANT_17310	8.27e-157	503.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_7167728_24	83406.HDN1F_34800	8.309e-09	64.0	2DSPU@1|root,33GZC@2|Bacteria,1NJ5W@1224|Proteobacteria,1SHAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WLSH2_k127_7167728_20	158189.SpiBuddy_1697	5.275e-26	115.0	COG0204@1|root,COG0204@2|Bacteria,2JAHQ@203691|Spirochaetes	203691|Spirochaetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH2_k127_7167728_15	926569.ANT_30860	7.331e-51	188.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH2_k127_7167728_8	1499967.BAYZ01000104_gene3630	6.29e-83	287.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	CP_0561	-	-	-	-	-	-	-	-	-	-	-	DUF1186
WLSH2_k127_7167728_0	926569.ANT_00270	5.637e-207	653.0	COG0044@1|root,COG0044@2|Bacteria,2G5N4@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
WLSH2_k127_7167728_21	1341181.FLJC2902T_27480	1.554e-20	95.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1IJY3@117743|Flavobacteriia,2P0P9@237|Flavobacterium	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WLSH2_k127_7167728_25	926569.ANT_04640	3.565e-08	57.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7198451_5	1123504.JQKD01000003_gene477	1.806e-29	122.0	COG1609@1|root,COG1609@2|Bacteria,1P1Q3@1224|Proteobacteria,2VJZ2@28216|Betaproteobacteria,4AFA2@80864|Comamonadaceae	28216|Betaproteobacteria	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
WLSH2_k127_7198451_6	326427.Cagg_1470	8.206e-29	117.0	COG3039@1|root,COG3039@2|Bacteria,2G8AP@200795|Chloroflexi	200795|Chloroflexi	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
WLSH2_k127_7198451_7	643562.Daes_0674	2.463e-25	115.0	COG0491@1|root,COG0491@2|Bacteria,1MUT2@1224|Proteobacteria,42MVA@68525|delta/epsilon subdivisions,2WKBW@28221|Deltaproteobacteria,2M89C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH2_k127_7198451_3	926569.ANT_16390	6.477e-46	169.0	2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7198451_0	926569.ANT_16400	7.577e-159	516.0	2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7198451_1	926569.ANT_15370	4.961e-97	333.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WLSH2_k127_7198451_2	926569.ANT_14530	4.523e-53	194.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WLSH2_k127_7198451_4	889378.Spiaf_2505	1.325e-44	171.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC	-	2.3.1.51,2.7.4.25	ko:K00655,ko:K00945	ko00240,ko00561,ko00564,ko01100,ko01110,map00240,map00561,map00564,map01100,map01110	M00052,M00089	R00158,R00512,R01665,R02241,R09381	RC00002,RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH2_k127_7223742_22	926569.ANT_22510	9.131e-54	192.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_7223742_31	926569.ANT_22500	3.117e-25	107.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
WLSH2_k127_7223742_9	926569.ANT_15320	1.576e-146	481.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cytoplasmic peptidoglycan synthetase domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH2_k127_7223742_2	357808.RoseRS_1605	1.455e-274	868.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,374Z8@32061|Chloroflexia	32061|Chloroflexia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WLSH2_k127_7223742_27	321327.CYA_0005	4.41e-45	173.0	COG0300@1|root,COG0300@2|Bacteria,1G2GZ@1117|Cyanobacteria,1H45Y@1129|Synechococcus	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_7223742_11	518766.Rmar_1893	6.997e-119	394.0	COG0006@1|root,COG0006@2|Bacteria,4NJI0@976|Bacteroidetes,1FIUI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
WLSH2_k127_7223742_25	402777.KB235904_gene3327	2.423e-50	196.0	2ECWT@1|root,30T28@2|Bacteria,1GDVQ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7223742_7	96561.Dole_3137	1.147e-168	538.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2WKA6@28221|Deltaproteobacteria,2MJK5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_7223742_40	1336245.JAGO01000011_gene190	1.108e-08	57.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XJCI@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
WLSH2_k127_7223742_10	518766.Rmar_2209	1.969e-137	445.0	COG3173@1|root,COG3173@2|Bacteria,4NFE7@976|Bacteroidetes,1FJU1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH2_k127_7223742_8	926550.CLDAP_36730	3.729e-168	536.0	COG1960@1|root,COG1960@2|Bacteria,2G5J5@200795|Chloroflexi	200795|Chloroflexi	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_7223742_12	926550.CLDAP_37110	5.896e-111	364.0	COG1028@1|root,COG1028@2|Bacteria	926550.CLDAP_37110|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7223742_17	742767.HMPREF9456_01660	1.141e-72	248.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,2FN7E@200643|Bacteroidia,22XSZ@171551|Porphyromonadaceae	976|Bacteroidetes	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
WLSH2_k127_7223742_14	744872.Spica_0914	1.507e-78	270.0	COG1647@1|root,COG1647@2|Bacteria	2|Bacteria	M	Serine aminopeptidase, S33	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
WLSH2_k127_7223742_18	926569.ANT_16080	9.183e-71	254.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
WLSH2_k127_7223742_20	926569.ANT_16090	3.185e-58	210.0	COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi	200795|Chloroflexi	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH2_k127_7223742_16	292459.STH2742	2.686e-73	263.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WLSH2_k127_7223742_15	644966.Tmar_0143	4.094e-78	273.0	COG5322@1|root,COG5322@2|Bacteria,1TQ2E@1239|Firmicutes,24A1Y@186801|Clostridia	186801|Clostridia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7223742_5	926569.ANT_16100	1.715e-215	679.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WLSH2_k127_7223742_26	926569.ANT_16110	9.537e-47	177.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi	200795|Chloroflexi	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WLSH2_k127_7223742_1	926550.CLDAP_14400	2.257e-291	912.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2G65R@200795|Chloroflexi	200795|Chloroflexi	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,malic
WLSH2_k127_7223742_21	1499967.BAYZ01000078_gene979	6.351e-57	205.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH2_k127_7223742_36	1499967.BAYZ01000078_gene980	2.816e-17	86.0	2DFUU@1|root,2ZT8J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7223742_6	926569.ANT_13200	2.418e-176	561.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
WLSH2_k127_7223742_42	926569.ANT_08720	1.187e-07	63.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	yneA	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
WLSH2_k127_7223742_29	1144275.COCOR_01127	4.675e-41	156.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TMP@68525|delta/epsilon subdivisions,2WR9C@28221|Deltaproteobacteria,2YV89@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WLSH2_k127_7223742_33	1499967.BAYZ01000110_gene3008	8.83e-23	108.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,rve,rve_3
WLSH2_k127_7223742_24	706587.Desti_5093	6.634e-53	190.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_7223742_34	1121456.ATVA01000019_gene1268	5.342e-19	88.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9,dCache_1
WLSH2_k127_7223742_37	1499967.BAYZ01000041_gene2393	8.297e-15	87.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HD_5,HisKA,PAS_4,Response_reg
WLSH2_k127_7223742_38	945713.IALB_0237	1.157e-12	74.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3290@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WLSH2_k127_7223742_4	926569.ANT_13210	3.184e-232	724.0	COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi	200795|Chloroflexi	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7223742_3	926569.ANT_13220	1.741e-249	782.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi	200795|Chloroflexi	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WLSH2_k127_7223742_30	1040986.ATYO01000006_gene376	3.348e-35	141.0	COG3896@1|root,COG3896@2|Bacteria,1NEN0@1224|Proteobacteria,2UI0A@28211|Alphaproteobacteria,43QHE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	V	Chloramphenicol phosphotransferase-like protein	-	-	-	ko:K18554	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CPT
WLSH2_k127_7223742_32	926569.ANT_13230	2.166e-24	104.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WLSH2_k127_7223742_39	1286631.X805_11620	4.069e-12	78.0	COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,2VV1E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
WLSH2_k127_7223742_41	1140003.I573_00208	2.698e-08	66.0	COG1388@1|root,COG2931@1|root,COG3883@1|root,COG1388@2|Bacteria,COG2931@2|Bacteria,COG3883@2|Bacteria,1U5CI@1239|Firmicutes,4ICBI@91061|Bacilli,4B54U@81852|Enterococcaceae	91061|Bacilli	Q	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
WLSH2_k127_7223742_0	926569.ANT_23100	0.0	1451.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH2_k127_7223742_19	926569.ANT_20740	1.936e-70	243.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_7223742_13	926569.ANT_20750	3.793e-80	276.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH2_k127_7223742_23	926569.ANT_13130	2.488e-53	189.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_7258642_8	551789.ATVJ01000002_gene2660	2.721e-19	91.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2TSXW@28211|Alphaproteobacteria,43X3N@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_7258642_4	926569.ANT_28040	3.883e-83	286.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi	200795|Chloroflexi	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WLSH2_k127_7258642_3	926569.ANT_22440	1.098e-89	310.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
WLSH2_k127_7258642_6	926569.ANT_22430	8.336e-27	111.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi	200795|Chloroflexi	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WLSH2_k127_7258642_5	926569.ANT_22420	3.436e-64	222.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH2_k127_7258642_7	926569.ANT_22410	4.881e-25	108.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi	200795|Chloroflexi	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WLSH2_k127_7258642_1	1121918.ARWE01000001_gene385	9.474e-164	526.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WTRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
WLSH2_k127_7258642_2	760192.Halhy_5983	1.851e-161	522.0	COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,1IPND@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b
WLSH2_k127_7258642_9	1200792.AKYF01000012_gene1083	5.483e-05	53.0	COG5492@1|root,COG5492@2|Bacteria,1VV9I@1239|Firmicutes,4HVK6@91061|Bacilli,26XQ5@186822|Paenibacillaceae	91061|Bacilli	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7258642_0	926569.ANT_28330	1.465e-186	608.0	COG0608@1|root,COG0608@2|Bacteria,2G7JK@200795|Chloroflexi	200795|Chloroflexi	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH2_k127_7272494_23	926569.ANT_28110	1.222e-21	96.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi	200795|Chloroflexi	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH2_k127_7272494_25	1116232.AHBF01000137_gene1924	2.398e-17	86.0	2AYAN@1|root,31QD6@2|Bacteria,2H0HE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7272494_13	926569.ANT_04240	4.363e-52	196.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WLSH2_k127_7272494_6	926569.ANT_11940	2.222e-112	368.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WLSH2_k127_7272494_1	926569.ANT_11950	9.149e-277	862.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
WLSH2_k127_7272494_0	469383.Cwoe_1617	0.0	1157.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CPS6@84995|Rubrobacteria	84995|Rubrobacteria	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WLSH2_k127_7272494_21	1033734.CAET01000016_gene4081	2.268e-25	117.0	COG3173@1|root,COG3173@2|Bacteria,1VE1X@1239|Firmicutes,4HM2B@91061|Bacilli,1ZGF6@1386|Bacillus	91061|Bacilli	S	Phosphotransferase enzyme family	aacA-aphD	-	2.7.1.190	ko:K17910	-	-	R11229	RC00002,RC00078	ko00000,ko01000,ko01504	-	-	-	APH
WLSH2_k127_7272494_14	383372.Rcas_1861	1.222e-50	192.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi,376N2@32061|Chloroflexia	32061|Chloroflexia	HP	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
WLSH2_k127_7272494_22	891968.Anamo_1739	1.656e-22	98.0	COG3585@1|root,COG3585@2|Bacteria,3TCMG@508458|Synergistetes	508458|Synergistetes	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	TOBE
WLSH2_k127_7272494_7	871968.DESME_01185	2.622e-88	301.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,2605W@186807|Peptococcaceae	186801|Clostridia	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WLSH2_k127_7272494_8	671143.DAMO_1144	8.234e-83	281.0	COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria	2|Bacteria	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
WLSH2_k127_7272494_10	56780.SYN_00839	2.629e-66	242.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42S6I@68525|delta/epsilon subdivisions,2WNNW@28221|Deltaproteobacteria,2MQGT@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ABC transporter	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K06857	ko02010,map02010	M00186,M00189	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.8	-	-	ABC_tran,TOBE
WLSH2_k127_7272494_11	1382356.JQMP01000001_gene921	5.643e-65	231.0	COG0725@1|root,COG0725@2|Bacteria,2G6J6@200795|Chloroflexi,27Y90@189775|Thermomicrobia	189775|Thermomicrobia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
WLSH2_k127_7272494_9	316274.Haur_2900	9.488e-68	240.0	COG4149@1|root,COG4149@2|Bacteria,2G6FA@200795|Chloroflexi,376FE@32061|Chloroflexia	32061|Chloroflexia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
WLSH2_k127_7272494_27	926569.ANT_01080	1.863e-14	74.0	COG3526@1|root,COG3526@2|Bacteria,2G7F3@200795|Chloroflexi	200795|Chloroflexi	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
WLSH2_k127_7272494_3	926569.ANT_01090	3.663e-163	518.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi	200795|Chloroflexi	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WLSH2_k127_7272494_12	926569.ANT_09390	1.143e-53	192.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi	200795|Chloroflexi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WLSH2_k127_7272494_20	1521187.JPIM01000005_gene2324	6.018e-27	117.0	COG3945@1|root,COG3945@2|Bacteria,2G96X@200795|Chloroflexi,377TS@32061|Chloroflexia	32061|Chloroflexia	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WLSH2_k127_7272494_16	926569.ANT_09400	1.632e-46	177.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WLSH2_k127_7272494_17	696281.Desru_2202	2.408e-46	173.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,Methyltransf_11,Methyltransf_23
WLSH2_k127_7272494_4	926569.ANT_25190	6.395e-146	475.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_7272494_15	926569.ANT_25180	1.472e-48	183.0	2FF2N@1|root,3470Y@2|Bacteria,2G9SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7272494_2	926569.ANT_25170	7.292e-175	557.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH2_k127_7272494_5	926569.ANT_25160	1.058e-141	462.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH2_k127_7272494_18	926569.ANT_25150	2.251e-34	135.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH2_k127_7272494_28	1122931.AUAE01000011_gene1723	1.208e-05	48.0	2DR8D@1|root,33ANQ@2|Bacteria,4NYGG@976|Bacteroidetes,2FVPJ@200643|Bacteroidia,22YX8@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7272494_26	877414.ATWA01000001_gene980	6.896e-16	78.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,267PG@186813|unclassified Clostridiales	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
WLSH2_k127_7296371_0	926569.ANT_03860	8.275e-202	637.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH2_k127_7296371_4	926569.ANT_03880	6.221e-35	139.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
WLSH2_k127_7296371_2	926569.ANT_03890	1.96e-63	231.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03890|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7296371_1	926569.ANT_28150	1.805e-133	443.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WLSH2_k127_7296371_3	926569.ANT_22510	4.302e-60	210.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_7300091_4	926569.ANT_09480	1.063e-135	441.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WLSH2_k127_7300091_7	926569.ANT_09470	2.724e-100	334.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi	200795|Chloroflexi	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
WLSH2_k127_7300091_6	926569.ANT_09460	9.127e-105	354.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
WLSH2_k127_7300091_0	926569.ANT_03560	7.338e-204	643.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WLSH2_k127_7300091_21	1082932.ATCR1_23233	1.007e-11	72.0	2DSXN@1|root,33HV3@2|Bacteria,1NI61@1224|Proteobacteria,2UW0C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
WLSH2_k127_7300091_19	561175.KB894093_gene2803	2.641e-23	108.0	arCOG12598@1|root,2ZACP@2|Bacteria,2IJWA@201174|Actinobacteria,4EP0Z@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
WLSH2_k127_7300091_1	765420.OSCT_2101	1.411e-200	637.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WLSH2_k127_7300091_3	1128421.JAGA01000002_gene1517	4.51e-144	468.0	COG3844@1|root,COG3844@2|Bacteria,2NS52@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-V	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WLSH2_k127_7300091_24	316274.Haur_1068	2.63e-06	59.0	COG2453@1|root,COG2453@2|Bacteria,2G7AB@200795|Chloroflexi,375W5@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Dual specificity protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
WLSH2_k127_7300091_20	1463881.KL591004_gene3686	3.312e-13	75.0	COG3187@1|root,COG3187@2|Bacteria,2I9ND@201174|Actinobacteria	201174|Actinobacteria	O	META domain	hslJ	-	-	ko:K03668	-	-	-	-	ko00000	-	-	-	META
WLSH2_k127_7300091_5	1128421.JAGA01000002_gene1693	6.35e-116	381.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_7300091_14	525904.Tter_1442	3.849e-37	150.0	COG4587@1|root,COG4587@2|Bacteria,2NQY6@2323|unclassified Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH2_k127_7300091_13	1382306.JNIM01000001_gene1765	2.16e-44	171.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH2_k127_7300091_12	1173027.Mic7113_1368	1.276e-46	186.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7HR@1150|Oscillatoriales	1117|Cyanobacteria	S	WD domain, G-beta repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,SpoIIE,TIR_2,WD40
WLSH2_k127_7300091_16	671143.DAMO_1988	5.366e-30	135.0	COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
WLSH2_k127_7300091_18	1521187.JPIM01000021_gene163	8.691e-24	111.0	COG3694@1|root,COG3694@2|Bacteria,2G90J@200795|Chloroflexi,377JE@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH2_k127_7300091_9	926560.KE387027_gene280	2.884e-75	261.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185,2.1.1.230	ko:K03218,ko:K05926	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind,TSNR_N
WLSH2_k127_7300091_10	926569.ANT_18630	3.246e-53	195.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
WLSH2_k127_7300091_15	1128421.JAGA01000002_gene1413	1.214e-36	149.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc
WLSH2_k127_7300091_2	926569.ANT_23020	1.114e-151	499.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WLSH2_k127_7300091_8	926569.ANT_23030	7.686e-99	341.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
WLSH2_k127_7300091_17	926569.ANT_08190	4.049e-25	106.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WLSH2_k127_7312364_7	926569.ANT_15410	3.161e-141	459.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
WLSH2_k127_7312364_41	926569.ANT_11720	1.318e-50	187.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NERD
WLSH2_k127_7312364_12	926569.ANT_11730	5.391e-110	365.0	COG0416@1|root,COG0416@2|Bacteria,2G5Z8@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WLSH2_k127_7312364_21	706587.Desti_5093	2.254e-82	311.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_7312364_34	357808.RoseRS_3061	1.146e-65	241.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
WLSH2_k127_7312364_26	1403313.AXBR01000005_gene1929	5.496e-76	266.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,4HCBR@91061|Bacilli,1ZCHF@1386|Bacillus	91061|Bacilli	Q	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
WLSH2_k127_7312364_9	1329516.JPST01000030_gene2948	1.337e-127	424.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,27BM5@186824|Thermoactinomycetaceae	91061|Bacilli	G	FGGY family of carbohydrate kinases, C-terminal domain	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
WLSH2_k127_7312364_17	580331.Thit_0161	6.454e-88	300.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,42HZQ@68295|Thermoanaerobacterales	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_7312364_35	1210884.HG799474_gene15148	2.939e-61	218.0	COG0800@1|root,COG0800@2|Bacteria,2IXBP@203682|Planctomycetes	203682|Planctomycetes	G	PFAM KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
WLSH2_k127_7312364_50	1227499.C493_11237	4.928e-09	67.0	COG0697@1|root,arCOG00272@2157|Archaea,2XVSM@28890|Euryarchaeota,23S7J@183963|Halobacteria	183963|Halobacteria	G	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_7312364_19	1123508.JH636440_gene1975	7.031e-84	289.0	COG0524@1|root,COG0524@2|Bacteria,2IWUH@203682|Planctomycetes	203682|Planctomycetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WLSH2_k127_7312364_5	760568.Desku_1633	7.266e-149	477.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia,26725@186807|Peptococcaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WLSH2_k127_7312364_8	1120746.CCNL01000017_gene2479	4.009e-133	433.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_7312364_16	1449126.JQKL01000003_gene1815	5.183e-93	317.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,2493N@186801|Clostridia,26BC7@186813|unclassified Clostridiales	186801|Clostridia	E	Glucose dehydrogenase C-terminus	-	-	1.1.1.103,1.1.1.14	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	M00014	R00875,R01465,R01896	RC00085,RC00102,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_7312364_31	1120746.CCNL01000017_gene2479	1.085e-67	243.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_7312364_25	706587.Desti_1412	2.211e-76	271.0	COG1600@1|root,COG1600@2|Bacteria,1N0WQ@1224|Proteobacteria,42ZPZ@68525|delta/epsilon subdivisions,2WV04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Reductive dehalogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dehalogenase,Fer4_16
WLSH2_k127_7312364_40	706587.Desti_1107	3.79e-51	188.0	COG2080@1|root,COG2080@2|Bacteria,1PGQD@1224|Proteobacteria,434AK@68525|delta/epsilon subdivisions,2X9WM@28221|Deltaproteobacteria,2MRQZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WLSH2_k127_7312364_1	309801.trd_A0069	2.017e-205	662.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_7312364_38	457421.CBFG_01101	2.358e-53	199.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
WLSH2_k127_7312364_45	570967.JMLV01000001_gene2713	4.745e-18	89.0	COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,2JSQF@204441|Rhodospirillales	204441|Rhodospirillales	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
WLSH2_k127_7312364_23	1242864.D187_003344	9.828e-78	277.0	COG1064@1|root,COG1064@2|Bacteria,1RAY7@1224|Proteobacteria	1224|Proteobacteria	S	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_7312364_42	1218352.B597_021855	1.546e-45	180.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,1SJQW@1236|Gammaproteobacteria,1Z2NE@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_7312364_48	634956.Geoth_2118	5.019e-13	72.0	COG1765@1|root,COG1765@2|Bacteria,1V3B2@1239|Firmicutes,4HIYY@91061|Bacilli	91061|Bacilli	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
WLSH2_k127_7312364_15	1123023.JIAI01000004_gene7873	1.319e-97	332.0	COG0006@1|root,COG0006@2|Bacteria,2IAJ8@201174|Actinobacteria	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
WLSH2_k127_7312364_13	351607.Acel_0890	4.274e-109	363.0	COG1073@1|root,COG1073@2|Bacteria,2GNST@201174|Actinobacteria,4EU2M@85013|Frankiales	201174|Actinobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100,Hydrolase_4
WLSH2_k127_7312364_37	138119.DSY0981	3.038e-55	206.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes	1239|Firmicutes	E	oxidoreductase	idhA	-	1.1.1.18,1.1.1.369,1.1.1.370	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951,R09953	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_7312364_4	1121877.JQKF01000029_gene2097	3.469e-160	514.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE9	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_7312364_51	70601.3256943	2.514e-05	51.0	COG1917@1|root,arCOG02994@2157|Archaea,2XZZJ@28890|Euryarchaeota,2448V@183968|Thermococci	183968|Thermococci	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_7312364_32	639283.Snov_0200	4.741e-67	240.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3F1EG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
WLSH2_k127_7312364_47	756883.Halar_1739	1.948e-13	81.0	COG0697@1|root,arCOG00272@2157|Archaea	2157|Archaea	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_7312364_27	1120983.KB894571_gene2471	5.443e-73	256.0	COG0410@1|root,COG0410@2|Bacteria	2|Bacteria	E	branched-chain amino acid transmembrane transporter activity	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WLSH2_k127_7312364_24	405948.SACE_4634	1.853e-76	265.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DY41@85010|Pseudonocardiales	201174|Actinobacteria	E	Branched-chain amino acid transport	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
WLSH2_k127_7312364_28	1352941.M877_35285	3.074e-72	256.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
WLSH2_k127_7312364_33	1209984.BN978_01516	1.445e-66	238.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,237FV@1762|Mycobacteriaceae	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH2_k127_7312364_14	1246995.AFR_18310	9.145e-104	351.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria	201174|Actinobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH2_k127_7312364_10	485913.Krac_9357	1.651e-125	415.0	COG0508@1|root,COG0508@2|Bacteria,2G6A9@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WLSH2_k127_7312364_0	485913.Krac_9358	8.996e-218	682.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
WLSH2_k127_7312364_3	1382306.JNIM01000001_gene2428	7.003e-170	539.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
WLSH2_k127_7312364_6	485913.Krac_9360	2.015e-141	455.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
WLSH2_k127_7312364_11	485913.Krac_9361	8.262e-120	391.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WLSH2_k127_7312364_29	485913.Krac_9362	2.131e-68	239.0	COG2186@1|root,COG2186@2|Bacteria,2G959@200795|Chloroflexi	200795|Chloroflexi	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WLSH2_k127_7312364_20	485913.Krac_9361	1.267e-82	284.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WLSH2_k127_7312364_46	311403.Arad_7196	3.062e-17	87.0	COG0662@1|root,COG0662@2|Bacteria,1P7SH@1224|Proteobacteria,2UW18@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_7312364_49	1323663.AROI01000033_gene4038	2.748e-10	70.0	COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,1RMZ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	hydratase	xylJ	-	4.2.1.132,4.2.1.80	ko:K18364	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R02601,R05864	RC00750,RC02676	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
WLSH2_k127_7312364_22	1163407.UU7_04737	1.006e-80	276.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
WLSH2_k127_7312364_18	1121422.AUMW01000005_gene665	5.232e-87	294.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,261BM@186807|Peptococcaceae	186801|Clostridia	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
WLSH2_k127_7312364_39	321327.CYA_0686	2.879e-52	196.0	COG0765@1|root,COG0765@2|Bacteria,1G0FV@1117|Cyanobacteria,1H13F@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	-	-	-	ko:K02029,ko:K02030,ko:K09971,ko:K17062	ko02010,map02010	M00232,M00236,M00587	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.12,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1,SBP_bac_3
WLSH2_k127_7312364_36	926550.CLDAP_18740	1.798e-55	205.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WLSH2_k127_7312364_44	926569.ANT_14650	2.463e-24	108.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
WLSH2_k127_7312364_2	926569.ANT_14670	1.225e-189	612.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_7312364_30	485913.Krac_0962	8.048e-68	252.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
WLSH2_k127_7312364_43	1382306.JNIM01000001_gene1621	1.201e-38	161.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene1621|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7319950_2	926569.ANT_16050	2.842e-197	623.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WLSH2_k127_7319950_16	926569.ANT_17270	1.487e-31	130.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
WLSH2_k127_7319950_17	383372.Rcas_2914	4.221e-20	102.0	2ECS5@1|root,336PT@2|Bacteria,2G96H@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
WLSH2_k127_7319950_4	383372.Rcas_2912	5.752e-137	442.0	COG0714@1|root,COG0714@2|Bacteria,2G8BI@200795|Chloroflexi,377XH@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH2_k127_7319950_7	357808.RoseRS_3183	9.482e-115	391.0	COG1721@1|root,COG1721@2|Bacteria,2G7JJ@200795|Chloroflexi	200795|Chloroflexi	M	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WLSH2_k127_7319950_9	1329516.JPST01000048_gene1882	5.947e-66	259.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,27BIZ@186824|Thermoactinomycetaceae	91061|Bacilli	O	Subtilase family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	PPC,Peptidase_S8
WLSH2_k127_7319950_5	455436.DS989811_gene1712	3.689e-133	474.0	COG2885@1|root,COG2931@1|root,COG3637@1|root,COG5276@1|root,COG2885@2|Bacteria,COG2931@2|Bacteria,COG3637@2|Bacteria,COG5276@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,46D2S@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	Cadherin_3,Calx-beta,He_PIG,HemolysinCabind,VWA_2
WLSH2_k127_7319950_11	118161.KB235922_gene2849	1.512e-57	231.0	COG3204@1|root,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_4,Cadherin,Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,PA14,SNase,SdiA-regulated
WLSH2_k127_7319950_15	1282361.ABAC402_02730	5.369e-43	161.0	COG0454@1|root,COG0456@2|Bacteria,1N9HC@1224|Proteobacteria,2UHGY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_7319950_10	157072.XP_008867643.1	1.648e-60	214.0	2D062@1|root,2SCYN@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7319950_6	926569.ANT_11320	1.241e-131	430.0	COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7319950_18	926569.ANT_11310	3.705e-19	88.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
WLSH2_k127_7319950_1	926569.ANT_11300	1.443e-201	643.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_7319950_3	926569.ANT_14380	1.385e-161	522.0	COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_7319950_8	926569.ANT_14370	3.912e-108	357.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
WLSH2_k127_7319950_12	1192034.CAP_8495	1.327e-55	207.0	COG4632@1|root,COG4632@2|Bacteria,1PIAX@1224|Proteobacteria,43DRZ@68525|delta/epsilon subdivisions,2WYR4@28221|Deltaproteobacteria,2Z0EH@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
WLSH2_k127_7319950_13	926569.ANT_19780	5.122e-52	194.0	COG2887@1|root,COG2887@2|Bacteria,2G8SQ@200795|Chloroflexi	200795|Chloroflexi	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
WLSH2_k127_7319950_0	926569.ANT_25410	1.637e-266	828.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WLSH2_k127_7319950_14	926569.ANT_03760	1.013e-48	176.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
WLSH2_k127_7346420_3	926569.ANT_05280	0.000885	46.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
WLSH2_k127_7346420_0	926569.ANT_05300	9.28e-261	820.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WLSH2_k127_7346420_1	926569.ANT_05310	7.673e-88	301.0	COG1622@1|root,COG2010@1|root,COG2197@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,COG2197@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
WLSH2_k127_7346420_2	926569.ANT_04260	1.714e-65	226.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH2_k127_7376991_4	926569.ANT_09840	9.948e-120	390.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WLSH2_k127_7376991_13	926569.ANT_09850	5.009e-38	151.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7376991_14	926569.ANT_09860	4.769e-37	145.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yyaR	-	-	ko:K06889,ko:K19273	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WLSH2_k127_7376991_1	926569.ANT_09870	2.925e-171	558.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
WLSH2_k127_7376991_8	926569.ANT_09880	3.855e-83	289.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	2|Bacteria	J	PFAM RNA binding S1 domain protein	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
WLSH2_k127_7376991_0	926569.ANT_09890	2.345e-220	705.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH2_k127_7376991_11	926569.ANT_09900	3.656e-59	211.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi	200795|Chloroflexi	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WLSH2_k127_7376991_6	926569.ANT_09910	1.665e-98	331.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH2_k127_7376991_7	926569.ANT_09920	1.541e-94	319.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_7376991_5	926569.ANT_09930	1.379e-103	353.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
WLSH2_k127_7376991_12	518766.Rmar_1910	4.021e-46	175.0	COG1234@1|root,COG1234@2|Bacteria,4PM5W@976|Bacteroidetes,1FJ9T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WLSH2_k127_7376991_10	926569.ANT_09940	2.384e-76	259.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi	200795|Chloroflexi	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
WLSH2_k127_7376991_9	941449.dsx2_0858	1.917e-79	274.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2M9EG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
WLSH2_k127_7376991_2	926550.CLDAP_22390	2.289e-134	440.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WLSH2_k127_7376991_3	926569.ANT_03450	2.999e-123	447.0	COG2203@1|root,COG3275@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3275@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GAF_2,GGDEF,HATPase_c,HD,HD_5,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
WLSH2_k127_7376991_15	935836.JAEL01000201_gene4586	4.682e-05	47.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7383275_7	192952.MM_0270	2.184e-16	83.0	arCOG06398@1|root,arCOG06398@2157|Archaea,2Y0SH@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7383275_8	192952.MM_0271	3.08e-15	79.0	arCOG03590@1|root,arCOG03590@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7383275_0	1121920.AUAU01000013_gene1700	0.0	1172.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	dapE	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2485,iIT341.HP0212	M20_dimer,Peptidase_M20
WLSH2_k127_7383275_1	526227.Mesil_0382	9.923e-289	901.0	COG1505@1|root,COG1505@2|Bacteria,1WMDW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WLSH2_k127_7383275_10	43989.cce_2831	6.543e-08	57.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,3KITD@43988|Cyanothece	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
WLSH2_k127_7383275_9	56110.Oscil6304_0817	5.376e-12	66.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,1HCTJ@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
WLSH2_k127_7383275_6	391612.CY0110_27475	1.774e-30	124.0	2C6B2@1|root,3318T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7383275_11	997346.HMPREF9374_1820	1.661e-05	56.0	29SNP@1|root,30DU9@2|Bacteria,1UBRB@1239|Firmicutes,4IN6D@91061|Bacilli,27CCG@186824|Thermoactinomycetaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7383275_2	1174528.JH992892_gene6439	1.486e-201	636.0	COG3033@1|root,COG3033@2|Bacteria,1G33V@1117|Cyanobacteria	1117|Cyanobacteria	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
WLSH2_k127_7383275_4	880073.Calab_3513	2.23e-88	308.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	pip	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Peptidase_S9
WLSH2_k127_7383275_5	760192.Halhy_1193	4.51e-66	236.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,1IXTS@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
WLSH2_k127_7383275_3	926569.ANT_13440	2.346e-99	334.0	COG4638@1|root,COG4638@2|Bacteria,2G75N@200795|Chloroflexi	200795|Chloroflexi	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
WLSH2_k127_7429776_0	926569.ANT_14570	1.949e-120	394.0	COG1111@1|root,COG1205@1|root,COG1403@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
WLSH2_k127_7429776_1	926569.ANT_21000	1.451e-48	182.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
WLSH2_k127_7429776_2	926569.ANT_15100	1.233e-39	154.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH2_k127_7453517_0	926569.ANT_05580	1.096e-97	328.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WLSH2_k127_7453517_4	504472.Slin_6131	6.923e-10	70.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WLSH2_k127_7453517_3	292459.STH2132	2.678e-10	74.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1VAC5@1239|Firmicutes,25EMF@186801|Clostridia	186801|Clostridia	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,Peptidase_M23
WLSH2_k127_7453517_5	926569.ANT_18580	0.0001822	52.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
WLSH2_k127_7453517_2	926550.CLDAP_18740	4.361e-23	104.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WLSH2_k127_7453517_1	395493.BegalDRAFT_0086	4.601e-91	308.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,1RQVZ@1236|Gammaproteobacteria,460BV@72273|Thiotrichales	72273|Thiotrichales	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
WLSH2_k127_7467515_2	1304885.AUEY01000002_gene356	8.494e-26	117.0	COG0778@1|root,COG1145@1|root,COG0778@2|Bacteria,COG1145@2|Bacteria,1R4E3@1224|Proteobacteria,42RVJ@68525|delta/epsilon subdivisions,2WNCQ@28221|Deltaproteobacteria,2MKVD@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Nitroreductase
WLSH2_k127_7467515_0	485913.Krac_4241	1.106e-146	482.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2G6K4@200795|Chloroflexi	200795|Chloroflexi	H	phosphoenolpyruvate synthase	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_7467515_1	768706.Desor_4320	1.109e-62	228.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,2642N@186807|Peptococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP pyruvate binding	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_7476404_0	272123.Anacy_0596	2.479e-273	854.0	COG4096@1|root,COG4096@2|Bacteria,1G3A8@1117|Cyanobacteria,1HQSE@1161|Nostocales	1117|Cyanobacteria	V	COGs COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
WLSH2_k127_7492515_5	1042877.GQS_02930	2.907e-40	160.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota	28890|Euryarchaeota	S	metal-dependent membrane protease	-	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0071944,GO:0080120,GO:0140096,GO:1901564	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_7492515_3	311424.DhcVS_701	4.12e-60	223.0	COG0842@1|root,COG0842@2|Bacteria,2G6II@200795|Chloroflexi,34D9V@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH2_k127_7492515_1	316274.Haur_4231	3.957e-104	346.0	COG1131@1|root,COG1131@2|Bacteria,2G7U2@200795|Chloroflexi,3779S@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_7492515_4	679926.Mpet_1639	2.186e-46	183.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y4MT@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
WLSH2_k127_7492515_2	406124.ACPC01000043_gene1820	4.676e-93	319.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,Sugar_tr
WLSH2_k127_7492515_0	1117108.PAALTS15_04111	5.98e-132	437.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HT6T@91061|Bacilli,26WHD@186822|Paenibacillaceae	91061|Bacilli	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH2_k127_7502486_15	1499967.BAYZ01000159_gene502	6.172e-07	60.0	COG2203@1|root,COG2208@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3437@2|Bacteria,2NQW9@2323|unclassified Bacteria	2|Bacteria	KT	Sigma factor PP2C-like phosphatases	rsbU	-	3.1.3.3,4.6.1.1	ko:K01079,ko:K01768,ko:K07315	ko00230,ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,ko02025,ko04113,ko04213,map00230,map00260,map00680,map01100,map01120,map01130,map01200,map01230,map02025,map04113,map04213	M00020,M00695	R00089,R00434,R00582	RC00017,RC00295	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	FHA,GAF,GAF_2,GAF_3,HATPase_c_2,Response_reg,SSF,SpoIIE
WLSH2_k127_7502486_4	1111069.TCCBUS3UF1_15690	1.336e-67	242.0	COG2202@1|root,COG3437@1|root,COG3829@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,1WJ3D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
WLSH2_k127_7502486_0	926569.ANT_15470	3.552e-274	859.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi	200795|Chloroflexi	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH2_k127_7502486_9	398579.Spea_1777	5.328e-28	117.0	2EXHW@1|root,33QU3@2|Bacteria,1NT7W@1224|Proteobacteria,1SM5Y@1236|Gammaproteobacteria,2QDB4@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7502486_8	1380370.JIBA01000003_gene2738	3.917e-34	150.0	2DQWK@1|root,3393J@2|Bacteria,2IEMK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7502486_14	402777.KB235898_gene4978	8.435e-10	72.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
WLSH2_k127_7502486_11	1104324.P186_0541	1.266e-22	108.0	COG0778@1|root,arCOG00288@2157|Archaea,2XQJA@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Nitroreductase	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
WLSH2_k127_7502486_3	479434.Sthe_2591	6.035e-75	265.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WLSH2_k127_7502486_12	479434.Sthe_3271	2.108e-15	79.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
WLSH2_k127_7502486_6	926569.ANT_13190	8.589e-55	199.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH2_k127_7502486_7	324602.Caur_2601	3.418e-53	202.0	COG0477@1|root,COG2814@2|Bacteria,2G6MT@200795|Chloroflexi,375W2@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
WLSH2_k127_7502486_10	429009.Adeg_2096	1.202e-22	108.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,42FBD@68295|Thermoanaerobacterales	186801|Clostridia	K	regulatory protein GntR HTH	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WLSH2_k127_7502486_5	1089553.Tph_c27670	8.02e-61	217.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548,ko:K14084	ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230	M00017,M00563	R00946,R09124,R09365	RC00035,RC00113,RC00732,RC01241,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
WLSH2_k127_7502486_2	1304874.JAFY01000002_gene574	8.252e-96	331.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
WLSH2_k127_7502486_1	1047013.AQSP01000134_gene1338	2.857e-114	386.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WLSH2_k127_7524738_10	926569.ANT_01180	6.424e-44	162.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
WLSH2_k127_7524738_4	926569.ANT_02480	3.895e-74	253.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WLSH2_k127_7524738_12	926569.ANT_00600	2.867e-22	99.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WLSH2_k127_7524738_9	926569.ANT_00590	2.229e-46	169.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WLSH2_k127_7524738_8	1123368.AUIS01000006_gene626	4.596e-47	175.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
WLSH2_k127_7524738_5	926569.ANT_26460	2.997e-69	244.0	COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WLSH2_k127_7524738_0	926569.ANT_26470	7.155e-107	360.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
WLSH2_k127_7524738_11	926560.KE387023_gene3144	4.55e-33	132.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WLSH2_k127_7524738_1	391625.PPSIR1_16360	5.823e-83	287.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WLSH2_k127_7524738_2	1120949.KB903311_gene777	1.436e-80	276.0	2DBF0@1|root,2Z8VT@2|Bacteria,2I88D@201174|Actinobacteria,4DIBF@85008|Micromonosporales	201174|Actinobacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	Steroid_dh
WLSH2_k127_7524738_14	926569.ANT_12030	1.878e-19	93.0	COG5660@1|root,COG5660@2|Bacteria,2G7CH@200795|Chloroflexi	200795|Chloroflexi	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WLSH2_k127_7524738_6	926569.ANT_12020	2.108e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
WLSH2_k127_7524738_7	926569.ANT_28850	3.489e-54	192.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
WLSH2_k127_7524738_3	926569.ANT_12050	1.642e-78	268.0	COG3634@1|root,COG3634@2|Bacteria,2G6SQ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WLSH2_k127_7524738_15	1218075.BAYA01000044_gene6607	2.728e-15	78.0	COG3238@1|root,COG3238@2|Bacteria	2|Bacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
WLSH2_k127_7524738_13	1158050.KB895453_gene977	1.466e-20	105.0	28IZ9@1|root,2Z8WS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
WLSH2_k127_7555556_5	926569.ANT_02250	6.755e-104	342.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WLSH2_k127_7555556_14	926569.ANT_02260	6.961e-32	127.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi	200795|Chloroflexi	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
WLSH2_k127_7555556_0	926569.ANT_02270	1.579e-205	657.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi	200795|Chloroflexi	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WLSH2_k127_7555556_6	926569.ANT_00470	3.942e-102	339.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_7555556_9	867845.KI911784_gene1451	5.822e-63	223.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	ntcA	-	-	ko:K01420,ko:K10716	-	-	-	-	ko00000,ko02000,ko03000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_7555556_16	760192.Halhy_1935	2.089e-14	76.0	2DI4K@1|root,3020V@2|Bacteria,4NV1J@976|Bacteroidetes,1IZFK@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WLSH2_k127_7555556_12	326427.Cagg_3325	9.421e-36	141.0	COG3118@1|root,COG3118@2|Bacteria,2G70B@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function (DUF2892)	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	DUF2892,Thioredoxin
WLSH2_k127_7555556_8	247490.KSU1_C0624	1.137e-71	254.0	COG1295@1|root,COG1295@2|Bacteria,2IYTS@203682|Planctomycetes	203682|Planctomycetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WLSH2_k127_7555556_3	926569.ANT_27790	1.213e-112	372.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_7555556_2	926550.CLDAP_35420	1.045e-172	552.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WLSH2_k127_7555556_13	926569.ANT_30040	1.085e-35	139.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WLSH2_k127_7555556_7	926569.ANT_23140	2.99e-88	305.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH2_k127_7555556_18	945713.IALB_1682	1.286e-07	56.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
WLSH2_k127_7555556_4	477974.Daud_0100	6.532e-104	346.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
WLSH2_k127_7555556_10	469381.Dpep_0826	2.941e-52	197.0	COG1893@1|root,COG1893@2|Bacteria,3TAIK@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
WLSH2_k127_7555556_15	926569.ANT_26960	3.335e-25	116.0	2EH75@1|root,33AYZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7555556_11	552811.Dehly_0442	1.169e-47	184.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
WLSH2_k127_7555556_1	926569.ANT_21940	3.683e-190	609.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
WLSH2_k127_7555556_17	1125863.JAFN01000001_gene2793	2.862e-14	86.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
WLSH2_k127_7558446_16	926569.ANT_19490	7.344e-56	199.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
WLSH2_k127_7558446_3	552811.Dehly_0435	4.504e-162	534.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WLSH2_k127_7558446_19	926569.ANT_19460	2.619e-38	149.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
WLSH2_k127_7558446_20	926550.CLDAP_40040	2.286e-37	147.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
WLSH2_k127_7558446_23	926569.ANT_19430	1.02e-30	128.0	2DRD8@1|root,33BA3@2|Bacteria,2G7EV@200795|Chloroflexi	200795|Chloroflexi	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
WLSH2_k127_7558446_14	926569.ANT_19420	9.473e-77	280.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
WLSH2_k127_7558446_9	926569.ANT_19410	4.937e-101	335.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
WLSH2_k127_7558446_11	926569.ANT_19400	3.302e-90	304.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
WLSH2_k127_7558446_12	926569.ANT_19390	2.522e-86	291.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
WLSH2_k127_7558446_2	926550.CLDAP_03390	4.494e-208	668.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
WLSH2_k127_7558446_15	3055.DAA00911	2.692e-64	231.0	COG1290@1|root,KOG4663@2759|Eukaryota,37QS7@33090|Viridiplantae,34J8E@3041|Chlorophyta	3041|Chlorophyta	C	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions	petB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035	-	ko:K02635	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrome_B
WLSH2_k127_7558446_28	138119.DSY0259	3.155e-17	89.0	COG1290@1|root,COG1290@2|Bacteria,1VJ5K@1239|Firmicutes,24U1A@186801|Clostridia,2650I@186807|Peptococcaceae	186801|Clostridia	C	Cytochrome b subunit of the bc complex	-	-	-	ko:K02637	ko00195,ko01100,map00195,map01100	M00162	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Cytochrom_B_C
WLSH2_k127_7558446_26	1453505.JASY01000002_gene3102	1.13e-22	104.0	COG2146@1|root,COG2146@2|Bacteria,4NMQ1@976|Bacteroidetes,1I3V0@117743|Flavobacteriia,2NSHS@237|Flavobacterium	976|Bacteroidetes	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
WLSH2_k127_7558446_4	768704.Desmer_1885	4.295e-151	498.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia,260K6@186807|Peptococcaceae	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
WLSH2_k127_7558446_21	1133849.O3I_004270	3.695e-36	142.0	COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria,4G1T9@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
WLSH2_k127_7558446_27	1347087.CBYO010000022_gene3643	2.635e-18	89.0	2E4BN@1|root,32Z79@2|Bacteria,1VQQV@1239|Firmicutes,4HRU8@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7558446_18	1379698.RBG1_1C00001G1687	3.833e-41	156.0	2DNQ8@1|root,32YJ3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7558446_13	1408473.JHXO01000002_gene3966	2.789e-86	289.0	COG0288@1|root,COG0288@2|Bacteria,4P0K1@976|Bacteroidetes,2FX9C@200643|Bacteroidia	976|Bacteroidetes	P	Carbonic anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	Pro_CA
WLSH2_k127_7558446_0	1121405.dsmv_1128	5.31e-304	956.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2MIS4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH2_k127_7558446_22	525904.Tter_1053	6.443e-35	141.0	COG0586@1|root,COG0586@2|Bacteria,2NPJ6@2323|unclassified Bacteria	2|Bacteria	S	SNARE associated Golgi protein	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH2_k127_7558446_6	671143.DAMO_0966	4.609e-139	451.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
WLSH2_k127_7558446_8	457429.ABJI02000833_gene2517	1.631e-106	358.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,KR,PP-binding,PS-DH
WLSH2_k127_7558446_7	926569.ANT_01810	3.117e-132	432.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_7558446_10	383372.Rcas_1163	2.589e-97	327.0	COG2199@1|root,COG3706@2|Bacteria,2G64S@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
WLSH2_k127_7558446_1	926569.ANT_28950	2.471e-259	808.0	COG0659@1|root,COG0659@2|Bacteria,2G7JI@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WLSH2_k127_7558446_31	710685.MycrhN_6290	1.553e-08	57.0	COG0748@1|root,COG0748@2|Bacteria,2IH29@201174|Actinobacteria,238WA@1762|Mycobacteriaceae	201174|Actinobacteria	P	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WLSH2_k127_7558446_24	562970.Btus_2971	1.276e-24	107.0	COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes,4HMFT@91061|Bacilli	91061|Bacilli	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
WLSH2_k127_7558446_25	330084.JNYZ01000035_gene9142	3.572e-23	104.0	COG0748@1|root,COG0748@2|Bacteria,2IFYD@201174|Actinobacteria,4E59B@85010|Pseudonocardiales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WLSH2_k127_7558446_29	247490.KSU1_C1143	2.371e-13	71.0	COG1943@1|root,COG1943@2|Bacteria,2J0GJ@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WLSH2_k127_7558446_17	340177.Cag_0809	4.219e-48	174.0	COG1943@1|root,COG1943@2|Bacteria,1FFM2@1090|Chlorobi	1090|Chlorobi	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WLSH2_k127_7559420_7	1114959.SZMC14600_16841	1.446e-09	66.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria,4E4KM@85010|Pseudonocardiales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WLSH2_k127_7559420_0	880073.Calab_0989	1.21e-149	479.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
WLSH2_k127_7559420_6	1521187.JPIM01000011_gene2651	8.57e-10	65.0	2ED7R@1|root,3374C@2|Bacteria,2GAGN@200795|Chloroflexi,3761Y@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7559420_5	1122137.AQXF01000004_gene1627	8.475e-21	96.0	COG3695@1|root,COG3695@2|Bacteria,1PZ1R@1224|Proteobacteria,2UWVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
WLSH2_k127_7559420_2	926569.ANT_30440	5.3e-67	240.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WLSH2_k127_7559420_4	926569.ANT_30450	6.374e-23	104.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7559420_1	926569.ANT_19820	1.357e-124	412.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WLSH2_k127_7559420_3	926550.CLDAP_11890	3.452e-53	200.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
WLSH2_k127_7559777_6	926569.ANT_14290	1.186e-132	447.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi	200795|Chloroflexi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
WLSH2_k127_7559777_17	1038859.AXAU01000013_gene6598	4.096e-27	115.0	COG3360@1|root,COG3360@2|Bacteria,1PE74@1224|Proteobacteria,2UCH8@28211|Alphaproteobacteria,3K04J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
WLSH2_k127_7559777_2	926569.ANT_15600	1.136e-172	566.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_7559777_20	1330700.JQNC01000003_gene1264	1.185e-10	69.0	2A1K0@1|root,30PTY@2|Bacteria,1WJQK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7559777_22	1229276.DI53_3010	1.097e-05	57.0	COG3568@1|root,COG3568@2|Bacteria,4NPXM@976|Bacteroidetes,1IXS4@117747|Sphingobacteriia	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WLSH2_k127_7559777_14	555088.DealDRAFT_2860	3.12e-47	179.0	COG1810@1|root,COG1810@2|Bacteria,1V28Y@1239|Firmicutes,24DXC@186801|Clostridia	186801|Clostridia	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF166
WLSH2_k127_7559777_16	1121272.KB903249_gene2255	3.692e-41	158.0	COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_7559777_5	485913.Krac_9200	3.066e-133	439.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
WLSH2_k127_7559777_7	926569.ANT_12000	1.603e-130	429.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WLSH2_k127_7559777_4	926569.ANT_12010	4.687e-137	443.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WLSH2_k127_7559777_13	867845.KI911784_gene3275	1.167e-47	179.0	COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi,375TP@32061|Chloroflexia	32061|Chloroflexia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WLSH2_k127_7559777_10	926569.ANT_09630	6.992e-70	248.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi	200795|Chloroflexi	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
WLSH2_k127_7559777_8	1254432.SCE1572_36630	1.176e-120	396.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MKW@68525|delta/epsilon subdivisions,2WKFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.11,3.5.3.17	ko:K01480,ko:K18459	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WLSH2_k127_7559777_3	926569.ANT_09640	3.557e-152	488.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH2_k127_7559777_18	123214.PERMA_1679	1.784e-14	79.0	COG0745@1|root,COG0745@2|Bacteria,2G4UZ@200783|Aquificae	200783|Aquificae	T	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_7559777_0	926569.ANT_05230	1.315e-280	873.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WLSH2_k127_7559777_11	765420.OSCT_3196	2.583e-63	230.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WLSH2_k127_7559777_15	635013.TherJR_1437	1.783e-44	167.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,2605S@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM competence damage-inducible protein CinA	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
WLSH2_k127_7559777_1	926569.ANT_14450	1.446e-185	586.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
WLSH2_k127_7559777_12	926569.ANT_14440	5.346e-49	181.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi	200795|Chloroflexi	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
WLSH2_k127_7559777_9	926569.ANT_14430	1.924e-78	269.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
WLSH2_k127_7563517_0	497965.Cyan7822_2631	1.429e-56	211.0	COG0419@1|root,COG2319@1|root,COG0419@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,3KH8A@43988|Cyanothece	1117|Cyanobacteria	L	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	WD40
WLSH2_k127_7563517_2	1382306.JNIM01000001_gene535	1.289e-09	66.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
WLSH2_k127_7563517_1	936053.I1BTM9	5.868e-10	64.0	2E7WT@1|root,2SEEZ@2759|Eukaryota,3AC4W@33154|Opisthokonta,3P9VQ@4751|Fungi,1GWXJ@112252|Fungi incertae sedis	4751|Fungi	I	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
WLSH2_k127_7563517_3	1303518.CCALI_02131	0.0002087	53.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria	2|Bacteria	M	serine-type peptidase activity	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
WLSH2_k127_7594706_1	1463856.JOHY01000140_gene7455	1.135e-08	67.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,rve,rve_3
WLSH2_k127_7594706_2	1128421.JAGA01000002_gene1964	1.276e-08	63.0	COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
WLSH2_k127_7594706_0	941639.BCO26_2227	1.189e-36	153.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1V41H@1239|Firmicutes,4HH52@91061|Bacilli,1ZHKF@1386|Bacillus	91061|Bacilli	L	DDE superfamily endonuclease	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_33
WLSH2_k127_7613384_4	926569.ANT_30920	1.145e-165	538.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	dppA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_7613384_5	926569.ANT_30910	3.426e-141	457.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_7613384_6	926569.ANT_30900	3.135e-124	404.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WLSH2_k127_7613384_7	1120953.AUBH01000004_gene2987	5.904e-118	388.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RQZ9@1236|Gammaproteobacteria,464MM@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WLSH2_k127_7613384_0	1499967.BAYZ01000013_gene6455	1.955e-220	698.0	COG0006@1|root,COG0006@2|Bacteria,2NNZX@2323|unclassified Bacteria	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9	ko:K01262,ko:K02027	-	M00207	-	-	ko00000,ko00002,ko01000,ko01002,ko02000	3.A.1.1	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
WLSH2_k127_7613384_1	926550.CLDAP_11260	1.591e-218	693.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WLSH2_k127_7613384_2	926550.CLDAP_23290	2.062e-199	644.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_7613384_10	1382306.JNIM01000001_gene3668	1.553e-17	95.0	COG0454@1|root,COG0456@2|Bacteria,2G9G9@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_7613384_3	926569.ANT_05370	3.568e-178	568.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WLSH2_k127_7613384_8	926569.ANT_30550	6.039e-69	243.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
WLSH2_k127_7613384_11	1454007.JAUG01000079_gene4542	5.306e-06	55.0	COG4914@1|root,COG4914@2|Bacteria,4NTQ4@976|Bacteroidetes,1ITBS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
WLSH2_k127_7613384_9	1128421.JAGA01000002_gene1694	2.586e-41	163.0	COG2176@1|root,COG2378@1|root,COG2176@2|Bacteria,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	dnaQ	-	2.7.7.7	ko:K02342,ko:K03763,ko:K13573	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03051,ko03400	-	-	-	GIY-YIG,RNase_T,VRR_NUC,WYL
WLSH2_k127_7702834_0	926569.ANT_25330	2.559e-45	179.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
WLSH2_k127_7702834_2	44251.PDUR_26195	2.651e-13	72.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,26U3R@186822|Paenibacillaceae	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_7702834_1	483219.LILAB_17275	9.459e-18	89.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,42PXQ@68525|delta/epsilon subdivisions,2WKHU@28221|Deltaproteobacteria,2YZ37@29|Myxococcales	28221|Deltaproteobacteria	L	COG1484 DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
WLSH2_k127_7702834_3	1117108.PAALTS15_27389	1.668e-05	51.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,26U3R@186822|Paenibacillaceae	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_7780257_3	926569.ANT_08030	4.367e-53	204.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WLSH2_k127_7780257_1	926569.ANT_03450	3.45e-77	275.0	COG2203@1|root,COG3275@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3275@2|Bacteria,COG3437@2|Bacteria,2G7KX@200795|Chloroflexi	2|Bacteria	T	HD domain	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GAF_2,GGDEF,HATPase_c,HD,HD_5,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
WLSH2_k127_7780257_2	443144.GM21_2262	2.885e-59	209.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH2_k127_7780257_0	357808.RoseRS_3061	2.021e-80	283.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
WLSH2_k127_7896092_1	1144275.COCOR_02428	6.403e-122	404.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X2MT@28221|Deltaproteobacteria,2YTVU@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WLSH2_k127_7896092_4	118168.MC7420_6045	7.438e-47	179.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH2_k127_7896092_0	1173028.ANKO01000065_gene5619	2.699e-209	689.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,1H919@1150|Oscillatoriales	1117|Cyanobacteria	V	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
WLSH2_k127_7896092_2	502025.Hoch_1167	2.308e-89	318.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2Z0JR@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
WLSH2_k127_7896092_3	502025.Hoch_1167	7.822e-77	280.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2Z0JR@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
WLSH2_k127_7909653_13	643473.KB235930_gene3727	9.395e-13	80.0	COG0457@1|root,COG1672@1|root,COG4249@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG4249@2|Bacteria,1G3A4@1117|Cyanobacteria,1HQV6@1161|Nostocales	1117|Cyanobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22
WLSH2_k127_7909653_6	1089553.Tph_c16790	1.862e-52	205.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,42GRQ@68295|Thermoanaerobacterales	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_7909653_5	926550.CLDAP_25650	1.64e-86	292.0	COG2267@1|root,COG2267@2|Bacteria,2G6DZ@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_7909653_0	1173028.ANKO01000065_gene5619	9.122e-212	696.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1G102@1117|Cyanobacteria,1H919@1150|Oscillatoriales	1117|Cyanobacteria	V	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
WLSH2_k127_7909653_8	313612.L8106_17667	9.421e-38	160.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
WLSH2_k127_7909653_4	56107.Cylst_1884	5.387e-103	348.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria,1HMT6@1161|Nostocales	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
WLSH2_k127_7909653_2	1242864.D187_000509	1.527e-111	369.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,42T4X@68525|delta/epsilon subdivisions,2WPCA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
WLSH2_k127_7909653_9	512565.AMIS_65270	1.049e-36	158.0	COG1075@1|root,COG3291@1|root,COG5563@1|root,COG1075@2|Bacteria,COG3291@2|Bacteria,COG5563@2|Bacteria,2H404@201174|Actinobacteria	201174|Actinobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,Lipase_2
WLSH2_k127_7909653_7	304371.MCP_1048	9.227e-48	179.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,2N96I@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM bifunctional deaminase-reductase domain protein	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
WLSH2_k127_7909653_3	1254432.SCE1572_28920	1.843e-105	347.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
WLSH2_k127_7909653_11	981369.JQMJ01000004_gene1732	2.926e-24	111.0	COG4221@1|root,COG4221@2|Bacteria,2I2Z8@201174|Actinobacteria,2NF2P@228398|Streptacidiphilus	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_7909653_1	1035308.AQYY01000002_gene479	6.397e-119	393.0	COG0707@1|root,COG0707@2|Bacteria,1UZ4A@1239|Firmicutes,249EE@186801|Clostridia	186801|Clostridia	M	PFAM Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth
WLSH2_k127_7909653_12	926569.ANT_00680	9.693e-18	87.0	COG4481@1|root,COG4481@2|Bacteria,2G7GI@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
WLSH2_k127_7909653_10	926569.ANT_00640	9.512e-36	139.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WLSH2_k127_7918719_2	667014.Thein_1499	3.727e-15	79.0	COG2405@1|root,COG2405@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
WLSH2_k127_7918719_0	163908.KB235896_gene2827	2.801e-24	104.0	COG2886@1|root,COG2886@2|Bacteria,1G8EZ@1117|Cyanobacteria,1HQ18@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
WLSH2_k127_7918719_3	767817.Desgi_2260	2.365e-12	68.0	COG2361@1|root,COG2361@2|Bacteria,1VFEB@1239|Firmicutes,24QN5@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
WLSH2_k127_7918719_1	32057.KB217478_gene7041	4.499e-24	104.0	COG1669@1|root,COG1669@2|Bacteria,1G7R5@1117|Cyanobacteria,1HQ1F@1161|Nostocales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
WLSH2_k127_7918719_4	118161.KB235922_gene5767	1.022e-09	61.0	COG1724@1|root,COG1724@2|Bacteria,1G9BE@1117|Cyanobacteria,3VKJT@52604|Pleurocapsales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
WLSH2_k127_7918719_5	251229.Chro_2247	6.589e-08	58.0	COG1598@1|root,COG1598@2|Bacteria,1G92J@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7920997_6	926569.ANT_02040	5.097e-44	162.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
WLSH2_k127_7920997_5	1122223.KB890692_gene3011	1.241e-80	276.0	COG4106@1|root,COG4106@2|Bacteria,1WMC7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Methyltransferase domain	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
WLSH2_k127_7920997_1	926569.ANT_02020	1.97e-145	468.0	COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WLSH2_k127_7920997_7	378806.STAUR_3873	1.224e-41	165.0	COG2267@1|root,COG2267@2|Bacteria,1RFE1@1224|Proteobacteria,42UMK@68525|delta/epsilon subdivisions,2WQNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WLSH2_k127_7920997_3	926569.ANT_02010	2.337e-125	405.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WLSH2_k127_7920997_9	357808.RoseRS_0904	6.391e-39	151.0	COG1262@1|root,COG1262@2|Bacteria,2GACQ@200795|Chloroflexi,375EB@32061|Chloroflexia	32061|Chloroflexia	S	Sulfatase-modifying factor enzyme 1	-	-	-	ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
WLSH2_k127_7920997_4	1220534.B655_0740	1.334e-88	313.0	arCOG02499@1|root,arCOG10865@1|root,arCOG02499@2157|Archaea,arCOG10865@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
WLSH2_k127_7920997_12	439235.Dalk_2289	3.315e-12	79.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
WLSH2_k127_7920997_10	1122176.KB903564_gene3177	4.094e-37	159.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	2|Bacteria	M	COG5337 Spore coat assembly protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,LTD
WLSH2_k127_7920997_11	93059.P9211_07661	4.825e-34	147.0	COG1285@1|root,COG1285@2|Bacteria	2|Bacteria	E	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
WLSH2_k127_7920997_8	93059.P9211_07681	2.715e-41	162.0	2DMQB@1|root,32SZR@2|Bacteria	2|Bacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
WLSH2_k127_7920997_0	909663.KI867150_gene944	2.553e-187	594.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2MQA7@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WLSH2_k127_7920997_2	926569.ANT_16180	4.563e-131	424.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WLSH2_k127_7958874_21	765952.PUV_08480	6.036e-06	55.0	COG5485@1|root,COG5485@2|Bacteria,2JHAF@204428|Chlamydiae	204428|Chlamydiae	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
WLSH2_k127_7958874_18	38727.Pavir.Fa00193.1.p	1.726e-17	86.0	KOG0118@1|root,KOG0118@2759|Eukaryota,37MBR@33090|Viridiplantae,3GC3A@35493|Streptophyta,3KRKX@4447|Liliopsida,3I69Q@38820|Poales	35493|Streptophyta	A	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	-	ko:K11294	ko05130,map05130	-	-	-	ko00000,ko00001,ko03009,ko03036	-	-	-	RRM_1
WLSH2_k127_7958874_19	443218.AS9A_2168	1.178e-09	65.0	COG3832@1|root,COG3832@2|Bacteria,2GVS1@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WLSH2_k127_7958874_0	1499967.BAYZ01000036_gene2418	0.0	1215.0	COG0438@1|root,COG0438@2|Bacteria,2NNZH@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WLSH2_k127_7958874_3	1499967.BAYZ01000036_gene2419	8.179e-157	499.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
WLSH2_k127_7958874_14	1131730.BAVI_13274	1.924e-55	203.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,1ZDR0@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
WLSH2_k127_7958874_6	931626.Awo_c16770	7.922e-119	392.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,25WNE@186806|Eubacteriaceae	186801|Clostridia	C	Malate/L-lactate dehydrogenase	mdh	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
WLSH2_k127_7958874_4	760568.Desku_3152	2.088e-146	478.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,260J4@186807|Peptococcaceae	186801|Clostridia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
WLSH2_k127_7958874_8	1111479.AXAR01000001_gene422	1.275e-100	342.0	COG0247@1|root,COG0247@2|Bacteria,1TR46@1239|Firmicutes,4HAY9@91061|Bacilli	91061|Bacilli	C	Glycolate oxidase	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
WLSH2_k127_7958874_15	1120950.KB892756_gene6662	3.473e-48	185.0	COG1063@1|root,COG1063@2|Bacteria,2GP97@201174|Actinobacteria,4DUAW@85009|Propionibacteriales	201174|Actinobacteria	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_7958874_1	118168.MC7420_5670	4.093e-180	572.0	COG3875@1|root,COG3875@2|Bacteria,1G82E@1117|Cyanobacteria,1HDBH@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
WLSH2_k127_7958874_20	1463861.JNXE01000017_gene7614	1.292e-09	65.0	COG0662@1|root,COG0662@2|Bacteria,2IH8K@201174|Actinobacteria	201174|Actinobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_7958874_7	1449976.KALB_2173	2.898e-105	351.0	COG0826@1|root,COG0826@2|Bacteria,2GKAK@201174|Actinobacteria,4E2YD@85010|Pseudonocardiales	201174|Actinobacteria	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7958874_5	760568.Desku_1633	2.594e-121	397.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia,26725@186807|Peptococcaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WLSH2_k127_7958874_2	760568.Desku_2951	6.836e-168	547.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,2604P@186807|Peptococcaceae	186801|Clostridia	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_7958874_22	1121440.AUMA01000007_gene1182	1.32e-05	49.0	COG1977@1|root,COG1977@2|Bacteria,1NH6M@1224|Proteobacteria,42X05@68525|delta/epsilon subdivisions,2WSK5@28221|Deltaproteobacteria,2MD55@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM ThiamineS	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
WLSH2_k127_7958874_12	1499967.BAYZ01000159_gene527	1.139e-67	237.0	COG0411@1|root,COG0411@2|Bacteria,2NNYG@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WLSH2_k127_7958874_11	1410665.JNKR01000001_gene606	9.656e-80	272.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4H223@909932|Negativicutes	909932|Negativicutes	E	ABC transporter, ATP-binding protein	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WLSH2_k127_7958874_13	1131730.BAVI_09806	1.11e-56	209.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,1ZBPA@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K11960	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
WLSH2_k127_7958874_16	1448860.BBJO01000042_gene1756	9.796e-45	174.0	COG4177@1|root,arCOG01274@2157|Archaea,2XVR5@28890|Euryarchaeota,241E9@183963|Halobacteria	183963|Halobacteria	E	branched-chain amino acid transport system, permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH2_k127_7958874_17	543728.Vapar_0643	1.246e-31	139.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2VPWN@28216|Betaproteobacteria,4AC19@80864|Comamonadaceae	28216|Betaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH2_k127_7958874_9	742738.HMPREF9460_04168	4.82e-82	287.0	COG1600@1|root,COG1600@2|Bacteria,1V0B5@1239|Firmicutes,24FDD@186801|Clostridia	186801|Clostridia	C	TIGRFAM reductive dehalogenase	-	-	-	-	-	-	-	-	-	-	-	-	Dehalogenase,Fer4_16,Fer4_7
WLSH2_k127_7958874_10	926569.ANT_07090	1.808e-80	275.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
WLSH2_k127_8018463_4	926569.ANT_15910	4.527e-102	334.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WLSH2_k127_8018463_8	926569.ANT_15900	1.519e-33	142.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH2_k127_8018463_7	926569.ANT_25890	2.3e-68	238.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WLSH2_k127_8018463_1	326427.Cagg_2762	5.088e-132	429.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WLSH2_k127_8018463_15	632292.Calhy_0731	0.0008146	43.0	2AX55@1|root,31P3J@2|Bacteria,1VWNW@1239|Firmicutes,252B9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8018463_14	368407.Memar_2438	0.000404	47.0	arCOG04662@1|root,arCOG04662@2157|Archaea,2XU93@28890|Euryarchaeota,2NBCG@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8018463_5	1499689.CCNN01000007_gene865	9.815e-91	316.0	COG1680@1|root,COG1680@2|Bacteria,1TRPT@1239|Firmicutes,2495H@186801|Clostridia,36WDR@31979|Clostridiaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Beta-lactamase,DUF302
WLSH2_k127_8018463_9	1009370.ALO_07578	1.1e-29	129.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,4H4K1@909932|Negativicutes	909932|Negativicutes	H	O-Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
WLSH2_k127_8018463_13	1423747.BAMJ01000037_gene1954	0.0002323	49.0	2DNW7@1|root,32ZGM@2|Bacteria,1V8QF@1239|Firmicutes,4HIIB@91061|Bacilli,3F601@33958|Lactobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8018463_2	324602.Caur_3475	8.174e-130	425.0	COG0438@1|root,COG0438@2|Bacteria,2G84C@200795|Chloroflexi,375HH@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11
WLSH2_k127_8018463_10	477974.Daud_0415	3.844e-24	110.0	COG2402@1|root,COG2402@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
WLSH2_k127_8018463_12	880072.Desac_0425	2.063e-06	53.0	2DSVR@1|root,33HKS@2|Bacteria	2|Bacteria	L	CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1,RHH_3,RHH_4
WLSH2_k127_8018463_6	926569.ANT_15880	9.937e-76	262.0	COG0500@1|root,COG2226@2|Bacteria,2G8SE@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_8018463_11	1120948.KB903219_gene718	1.143e-20	101.0	COG2227@1|root,COG2227@2|Bacteria,2HJ6J@201174|Actinobacteria,4E7I0@85010|Pseudonocardiales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WLSH2_k127_8018463_0	926569.ANT_15870	3.41e-166	547.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
WLSH2_k127_8018463_3	926569.ANT_15860	5.902e-117	402.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
WLSH2_k127_8103616_1	926569.ANT_26640	2.928e-100	340.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WLSH2_k127_8103616_0	926569.ANT_26640	4.592e-101	349.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WLSH2_k127_8103616_2	243233.MCA1022	2.411e-60	211.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XDN6@135618|Methylococcales	135618|Methylococcales	H	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_8191844_3	926569.ANT_13240	1.431e-110	364.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WLSH2_k127_8191844_2	1449126.JQKL01000003_gene1729	1.137e-132	431.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,268FY@186813|unclassified Clostridiales	186801|Clostridia	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WLSH2_k127_8191844_1	926569.ANT_13260	3.858e-159	512.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
WLSH2_k127_8191844_4	926569.ANT_13270	3.852e-88	301.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WLSH2_k127_8191844_0	926550.CLDAP_19050	7.101e-182	578.0	COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_8191844_6	926569.ANT_08030	8.553e-44	181.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WLSH2_k127_8191844_7	926559.JoomaDRAFT_3556	5.752e-23	115.0	COG1361@1|root,COG3291@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,COG5492@2|Bacteria,4NDZC@976|Bacteroidetes,1IKB7@117743|Flavobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cu-binding_MopE,DUF11,HYR,Laminin_G_3,PKD,SprB
WLSH2_k127_8191844_5	1385517.N800_00720	3.017e-71	264.0	COG1361@1|root,COG3188@1|root,COG1361@2|Bacteria,COG3188@2|Bacteria,1R5G4@1224|Proteobacteria,1T61M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WLSH2_k127_8214452_7	765420.OSCT_0637	3.165e-10	62.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,37511@32061|Chloroflexia	32061|Chloroflexia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH2_k127_8214452_0	1089553.Tph_c20850	3.315e-150	497.0	COG0553@1|root,COG0553@2|Bacteria,1TQ5E@1239|Firmicutes,25C98@186801|Clostridia,42F1Q@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,SNF2_N
WLSH2_k127_8214452_6	1089553.Tph_c20840	2.867e-13	83.0	28PHK@1|root,2ZC81@2|Bacteria,1V1PM@1239|Firmicutes,24GII@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8214452_3	383372.Rcas_1611	2.682e-66	234.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
WLSH2_k127_8214452_2	383372.Rcas_1610	1.394e-81	282.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WLSH2_k127_8214452_4	1487921.DP68_13745	7.722e-48	177.0	COG1995@1|root,COG1995@2|Bacteria,1TQGT@1239|Firmicutes,24A12@186801|Clostridia,36E2Z@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
WLSH2_k127_8214452_1	330214.NIDE0660	8.114e-150	483.0	COG1373@1|root,COG1373@2|Bacteria,3J14P@40117|Nitrospirae	40117|Nitrospirae	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH2_k127_8214452_8	1245469.S58_20930	3.916e-09	66.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2U0A3@28211|Alphaproteobacteria,3JXCG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_8214452_5	572477.Alvin_0642	3.132e-28	119.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
WLSH2_k127_8214452_9	485913.Krac_2962	0.0005777	48.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
WLSH2_k127_8214786_25	926560.KE387023_gene2230	1.306e-25	118.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_8214786_4	502025.Hoch_3647	3.095e-158	507.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
WLSH2_k127_8214786_15	1382306.JNIM01000001_gene1873	4.425e-80	288.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
WLSH2_k127_8214786_20	926569.ANT_14350	1.379e-41	159.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi	200795|Chloroflexi	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
WLSH2_k127_8214786_1	926569.ANT_14340	2.913e-195	631.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
WLSH2_k127_8214786_24	926569.ANT_14330	1.176e-26	114.0	COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi	200795|Chloroflexi	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
WLSH2_k127_8214786_21	926569.ANT_14320	1.807e-38	147.0	COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
WLSH2_k127_8214786_9	926569.ANT_14310	1.766e-113	372.0	COG0648@1|root,COG0648@2|Bacteria	2|Bacteria	L	deoxyribonuclease IV (phage-T4-induced) activity	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
WLSH2_k127_8214786_17	994573.T472_0209610	3.044e-59	216.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
WLSH2_k127_8214786_26	1121875.KB907547_gene3493	3.319e-19	89.0	COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,1HWTV@117743|Flavobacteriia	976|Bacteroidetes	IQ	Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate	idnO	-	1.1.1.127,1.1.1.69	ko:K00046,ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WLSH2_k127_8214786_18	926560.KE387026_gene4264	2.22e-58	209.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	LysE
WLSH2_k127_8214786_3	926569.ANT_26630	9.28e-161	511.0	COG0667@1|root,COG0667@2|Bacteria,2G5VT@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_8214786_5	85643.Tmz1t_2450	4.851e-141	455.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
WLSH2_k127_8214786_7	926569.ANT_30570	2.531e-131	429.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
WLSH2_k127_8214786_0	926569.ANT_30560	3.1e-203	641.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
WLSH2_k127_8214786_16	926569.ANT_02510	1.522e-74	258.0	COG1120@1|root,COG1120@2|Bacteria,2G6QS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WLSH2_k127_8214786_19	1007103.AFHW01000032_gene2252	7.915e-55	198.0	COG0454@1|root,COG0456@2|Bacteria,1V2CK@1239|Firmicutes,4HGP5@91061|Bacilli,26WI0@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	yyaR	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_8214786_8	926569.ANT_02520	5.658e-117	385.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WLSH2_k127_8214786_12	926569.ANT_02530	5.259e-92	312.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi	200795|Chloroflexi	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WLSH2_k127_8214786_13	518766.Rmar_1606	2.488e-88	306.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
WLSH2_k127_8214786_6	1089550.ATTH01000001_gene2135	4.219e-139	458.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
WLSH2_k127_8214786_11	926550.CLDAP_18870	1.88e-107	377.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WLSH2_k127_8214786_28	867845.KI911784_gene2110	5.419e-05	51.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
WLSH2_k127_8214786_10	926569.ANT_23150	5.098e-113	376.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH2_k127_8214786_23	262724.TT_C0883	1.325e-31	130.0	COG4319@1|root,COG4319@2|Bacteria,1WJSX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Calcium calmodulin dependent protein kinase II	-	-	-	-	-	-	-	-	-	-	-	-	CaMKII_AD
WLSH2_k127_8214786_14	926569.ANT_02410	2.808e-81	284.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pelF	-	-	ko:K21011,ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4,Glycos_transf_1
WLSH2_k127_8214786_2	269797.Mbar_A1244	1.475e-166	535.0	COG0520@1|root,arCOG00065@2157|Archaea	2157|Archaea	E	COG0520 Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WLSH2_k127_8214786_27	926569.ANT_10860	1.218e-09	61.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WLSH2_k127_825055_11	871968.DESME_08490	1.021e-29	123.0	arCOG06631@1|root,32RY6@2|Bacteria,1V8RP@1239|Firmicutes,24MV5@186801|Clostridia,264X8@186807|Peptococcaceae	186801|Clostridia	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_825055_10	266117.Rxyl_3108	3.107e-46	180.0	COG4714@1|root,COG4714@2|Bacteria	2|Bacteria	EGP	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
WLSH2_k127_825055_6	926569.ANT_06510	9.103e-110	375.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	PMT_2
WLSH2_k127_825055_5	926569.ANT_06420	4.997e-128	418.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ptmF	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_825055_8	903818.KI912268_gene1808	1.755e-55	213.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT_2
WLSH2_k127_825055_0	926569.ANT_03250	2.349e-269	839.0	COG0129@1|root,COG0129@2|Bacteria,2G5QW@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
WLSH2_k127_825055_3	311424.DhcVS_737	7.434e-205	651.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,34CWN@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WLSH2_k127_825055_7	448385.sce3731	1.13e-55	199.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria,2Z0D5@29|Myxococcales	28221|Deltaproteobacteria	E	ACT domain	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
WLSH2_k127_825055_4	926569.ANT_03280	2.619e-176	557.0	COG0059@1|root,COG0059@2|Bacteria,2G5NP@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
WLSH2_k127_825055_1	1254432.SCE1572_22465	3.478e-228	719.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YUCI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
WLSH2_k127_825055_2	383372.Rcas_1549	6.989e-226	708.0	COG0065@1|root,COG0065@2|Bacteria,2G68G@200795|Chloroflexi,3753P@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WLSH2_k127_825055_12	1300345.LF41_2396	2.646e-10	67.0	COG3756@1|root,COG3756@2|Bacteria,1R95D@1224|Proteobacteria,1RQF3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1376)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1376
WLSH2_k127_8298833_2	768671.ThimaDRAFT_4913	1.192e-14	74.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_8298833_0	1121335.Clst_0501	1.479e-124	415.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WGEA@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
WLSH2_k127_8298833_1	926569.ANT_07670	3.581e-41	161.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH2_k127_8303335_16	316056.RPC_3945	3.135e-08	55.0	COG0664@1|root,COG0664@2|Bacteria,1NPY0@1224|Proteobacteria,2TT13@28211|Alphaproteobacteria,3JQT0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Crp Fnr family	nnrR	-	-	ko:K21564	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_8303335_1	391937.NA2_09121	3.54e-131	439.0	COG1622@1|root,COG2132@1|root,COG1622@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2U1BK@28211|Alphaproteobacteria,43JBX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	nitrite reductase, copper-containing	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C
WLSH2_k127_8303335_13	927677.ALVU02000001_gene1960	5.029e-17	92.0	COG3266@1|root,COG3266@2|Bacteria,1G5GU@1117|Cyanobacteria,1H5WU@1142|Synechocystis	1117|Cyanobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8303335_12	316274.Haur_1185	1.937e-32	132.0	COG0454@1|root,COG0456@2|Bacteria,2G9MN@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_8303335_3	926569.ANT_10380	1.643e-102	344.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
WLSH2_k127_8303335_11	926569.ANT_10350	1.518e-42	159.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WLSH2_k127_8303335_9	926569.ANT_10340	3.79e-51	186.0	COG0102@1|root,COG0102@2|Bacteria,2G6M4@200795|Chloroflexi	200795|Chloroflexi	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WLSH2_k127_8303335_6	926569.ANT_10330	9.669e-71	247.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WLSH2_k127_8303335_10	926569.ANT_10320	4.341e-49	178.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WLSH2_k127_8303335_0	926569.ANT_10310	4.506e-161	511.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WLSH2_k127_8303335_4	926569.ANT_10300	4.292e-90	301.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WLSH2_k127_8303335_7	926569.ANT_10290	2.482e-62	216.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WLSH2_k127_8303335_8	926569.ANT_10280	2.911e-62	215.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WLSH2_k127_8303335_15	926569.ANT_10270	1.888e-13	71.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WLSH2_k127_8303335_2	926569.ANT_10260	1.238e-106	351.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi	200795|Chloroflexi	J	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WLSH2_k127_8303335_5	926569.ANT_10250	4.804e-79	270.0	COG0563@1|root,COG0563@2|Bacteria,2G6GP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WLSH2_k127_8303335_14	926569.ANT_10240	2.188e-14	75.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi	200795|Chloroflexi	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WLSH2_k127_8315323_5	357808.RoseRS_3061	1.085e-84	302.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
WLSH2_k127_8315323_3	357808.RoseRS_3061	2.062e-86	302.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
WLSH2_k127_8315323_20	1195236.CTER_2520	2.182e-18	89.0	COG1680@1|root,COG1680@2|Bacteria,1TR9E@1239|Firmicutes,2480P@186801|Clostridia,3WRFA@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_8315323_16	1170562.Cal6303_5638	5.514e-32	135.0	COG3464@1|root,COG3464@2|Bacteria,1G6BF@1117|Cyanobacteria	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8315323_25	485913.Krac_1983	2.219e-06	50.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yycN	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WLSH2_k127_8315323_24	762550.LEGAS_0016	7.699e-08	56.0	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli,4AXT1@81850|Leuconostocaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	yycN	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_8315323_13	243231.GSU1656	4.255e-45	175.0	COG2199@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2204@2|Bacteria,1QVAY@1224|Proteobacteria,42TG1@68525|delta/epsilon subdivisions,2WVCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response receiver sensor diguanylate cyclase, PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,Response_reg
WLSH2_k127_8315323_4	706587.Desti_5093	9.623e-85	311.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_8315323_0	439235.Dalk_4226	8.654e-263	818.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2MHY2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
WLSH2_k127_8315323_23	945713.IALB_0174	3.496e-13	72.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,DUF559,HSDR_N,ResIII
WLSH2_k127_8315323_21	1487953.JMKF01000016_gene2553	5.631e-15	78.0	2E46G@1|root,32Z2E@2|Bacteria,1G8V4@1117|Cyanobacteria,1HGBS@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8315323_18	1487953.JMKF01000016_gene2554	5.302e-25	106.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,1HCTJ@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
WLSH2_k127_8315323_8	926560.KE387025_gene4131	2.807e-64	230.0	COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_8315323_11	485913.Krac_8102	2.817e-53	191.0	2FA33@1|root,342C2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8315323_15	649638.Trad_1432	1.848e-40	151.0	COG3093@1|root,COG3093@2|Bacteria,1WKRB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG3093 Plasmid maintenance system antidote protein	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WLSH2_k127_8315323_14	649638.Trad_1431	1.817e-40	151.0	COG3549@1|root,COG3549@2|Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HigB-like_toxin
WLSH2_k127_8315323_17	195250.CM001776_gene3312	4.498e-26	115.0	COG0212@1|root,COG0212@2|Bacteria,1G5WS@1117|Cyanobacteria,1H10N@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
WLSH2_k127_8315323_10	926569.ANT_13760	7.736e-60	214.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WLSH2_k127_8315323_12	926569.ANT_13740	1.788e-52	189.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi	200795|Chloroflexi	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WLSH2_k127_8315323_1	926569.ANT_13730	3.922e-98	326.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WLSH2_k127_8315323_6	926569.ANT_18610	1.221e-73	257.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH2_k127_8315323_9	395493.BegalDRAFT_3447	4.06e-60	213.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,1S3WT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	HD domain	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
WLSH2_k127_8315323_2	1521187.JPIM01000001_gene834	1.593e-89	311.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_8315323_19	357808.RoseRS_2242	8.836e-21	93.0	COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_8348829_6	926569.ANT_13130	1.087e-94	315.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_8348829_2	926569.ANT_13370	5.604e-217	681.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
WLSH2_k127_8348829_7	926569.ANT_13360	2.021e-78	269.0	COG0584@1|root,COG0584@2|Bacteria,2G6YD@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WLSH2_k127_8348829_1	926569.ANT_13340	4.223e-255	816.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
WLSH2_k127_8348829_4	926569.ANT_13330	3.016e-141	455.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WLSH2_k127_8348829_8	926569.ANT_13320	1.249e-77	267.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc,RDD,Trans_reg_C,Yop-YscD_cpl
WLSH2_k127_8348829_20	926569.ANT_25610	3.382e-05	55.0	COG4254@1|root,COG4254@2|Bacteria,2G9J2@200795|Chloroflexi	200795|Chloroflexi	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WLSH2_k127_8348829_9	326427.Cagg_3759	1.426e-35	143.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WLSH2_k127_8348829_17	326427.Cagg_3758	4.629e-15	87.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8348829_0	670487.Ocepr_1935	3.605e-259	824.0	COG0433@1|root,COG1196@1|root,COG0433@2|Bacteria,COG1196@2|Bacteria,1WM64@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8348829_13	1094980.Mpsy_0307	7.415e-27	117.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y2AR@28890|Euryarchaeota,2NA7W@224756|Methanomicrobia	224756|Methanomicrobia	O	NnrU protein	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU
WLSH2_k127_8348829_3	926569.ANT_06210	3.606e-199	638.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
WLSH2_k127_8348829_14	926569.ANT_06190	8.939e-25	105.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_25,Trm112p
WLSH2_k127_8348829_18	926550.CLDAP_05870	4.866e-13	77.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WLSH2_k127_8348829_5	926569.ANT_06180	1.358e-102	352.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WLSH2_k127_8348829_19	84531.JMTZ01000002_gene758	6.115e-07	63.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.4.21.50,3.4.24.3	ko:K01337,ko:K01387,ko:K03933,ko:K12287	-	-	-	-	ko00000,ko01000,ko01002,ko02042,ko02044	-	AA10,CBM73	-	DUF11,PKD,P_proprotein,SdrD_B
WLSH2_k127_8348829_12	748247.AZKH_1545	1.203e-27	131.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,DUF4347,DUF5122,HemolysinCabind,Lactonase,Laminin_G_3,Peptidase_M10_C,VWA_2,W_rich_C
WLSH2_k127_840648_6	395494.Galf_1506	1.065e-05	52.0	COG2815@1|root,COG2815@2|Bacteria,1N5XX@1224|Proteobacteria,2VXHF@28216|Betaproteobacteria	28216|Betaproteobacteria	L	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
WLSH2_k127_840648_2	1894.JOER01000058_gene3221	2.021e-37	154.0	COG0265@1|root,COG2319@1|root,COG0265@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2,WD40
WLSH2_k127_840648_0	311424.DhcVS_1416	3.666e-249	785.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,34CKH@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_840648_3	1173026.Glo7428_2619	2.338e-31	125.0	2E46S@1|root,32Z2Q@2|Bacteria,1G7MJ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_840648_5	311424.DhcVS_1416	3.053e-10	61.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,34CKH@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_840648_1	1288826.MSNKSG1_11023	5.566e-149	515.0	COG1800@1|root,COG1800@2|Bacteria,1R2PF@1224|Proteobacteria,1T5UY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_841471_0	211114.JOEF01000003_gene3012	9.953e-202	642.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
WLSH2_k127_841471_4	1283299.AUKG01000002_gene4309	2.447e-57	211.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria	84995|Rubrobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
WLSH2_k127_841471_3	580331.Thit_1582	1.407e-93	321.0	COG0176@1|root,COG0176@2|Bacteria,1U9RA@1239|Firmicutes,24DCI@186801|Clostridia,42IE1@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Transaldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
WLSH2_k127_841471_1	1499967.BAYZ01000117_gene3322	4.612e-142	456.0	COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria	2|Bacteria	G	Fructose-bisphosphate aldolase class-II	fba2	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,PHP
WLSH2_k127_841471_2	1499967.BAYZ01000117_gene3321	7.68e-117	379.0	COG0079@1|root,COG0079@2|Bacteria,2NNZK@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	hisD	-	1.1.1.23,2.6.1.9	ko:K00013,ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03243	RC00006,RC00099,RC00242,RC00463,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,Histidinol_dh
WLSH2_k127_8434118_34	926569.ANT_11280	1.393e-20	93.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
WLSH2_k127_8434118_12	926569.ANT_11270	1.125e-88	298.0	COG1811@1|root,COG1811@2|Bacteria,2G6S2@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
WLSH2_k127_8434118_26	1150399.AQYK01000001_gene1643	9.031e-47	178.0	29YCS@1|root,30K75@2|Bacteria,2IJFN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8434118_27	1540257.JQMW01000009_gene3132	1.172e-35	146.0	COG1051@1|root,COG1051@2|Bacteria,1V3MM@1239|Firmicutes,24I7G@186801|Clostridia,36K3A@31979|Clostridiaceae	186801|Clostridia	F	NUDIX domain	-	-	-	ko:K12944	-	-	-	-	ko00000,ko01000	-	-	-	NUDIX
WLSH2_k127_8434118_29	757424.Hsero_0066	1.236e-30	132.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2VNGN@28216|Betaproteobacteria,4776R@75682|Oxalobacteraceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_8434118_6	926569.ANT_09040	1.192e-134	445.0	COG0265@1|root,COG0265@2|Bacteria,2G821@200795|Chloroflexi	200795|Chloroflexi	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
WLSH2_k127_8434118_20	926569.ANT_31670	1.364e-59	213.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi	200795|Chloroflexi	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WLSH2_k127_8434118_18	926569.ANT_31660	7.259e-64	226.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
WLSH2_k127_8434118_28	580331.Thit_0539	1.486e-31	138.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
WLSH2_k127_8434118_15	926569.ANT_31640	1.329e-76	270.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH2_k127_8434118_0	926569.ANT_31630	2.578e-200	636.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WLSH2_k127_8434118_5	926569.ANT_31620	5.878e-135	436.0	COG0451@1|root,COG0451@2|Bacteria,2G6S4@200795|Chloroflexi	200795|Chloroflexi	M	Short-chain dehydrogenase reductase SDR	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WLSH2_k127_8434118_11	926569.ANT_31610	6.552e-95	327.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	wzx	-	-	ko:K16694	-	-	-	-	ko00000,ko02000	2.A.66.2.6	-	-	Polysacc_synt_3
WLSH2_k127_8434118_9	926569.ANT_00620	3.389e-105	362.0	COG0438@1|root,COG0438@2|Bacteria,2G9D7@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
WLSH2_k127_8434118_25	1499967.BAYZ01000061_gene5942	1.026e-47	181.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Cu_amine_oxidN1,PD40
WLSH2_k127_8434118_31	909663.KI867150_gene337	3.769e-27	116.0	COG0823@1|root,COG0823@2|Bacteria,1Q2D4@1224|Proteobacteria,437ZF@68525|delta/epsilon subdivisions,2X39G@28221|Deltaproteobacteria,2MSI3@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8434118_2	379066.GAU_1970	2.565e-158	503.0	COG1089@1|root,COG1089@2|Bacteria,1ZSR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WLSH2_k127_8434118_4	926569.ANT_06170	2.908e-146	468.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_8434118_19	926569.ANT_06160	3.869e-61	223.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH2_k127_8434118_3	401526.TcarDRAFT_2659	7.271e-148	476.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4H3A2@909932|Negativicutes	909932|Negativicutes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WLSH2_k127_8434118_7	1170562.Cal6303_2142	8.781e-126	410.0	COG1209@1|root,COG1209@2|Bacteria,1G091@1117|Cyanobacteria,1HJMN@1161|Nostocales	1117|Cyanobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WLSH2_k127_8434118_30	381764.Fnod_0206	1.275e-30	125.0	COG2030@1|root,COG2030@2|Bacteria,2GD2R@200918|Thermotogae	200918|Thermotogae	I	PFAM MaoC domain protein dehydratase	-	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
WLSH2_k127_8434118_13	1229172.JQFA01000002_gene2048	2.155e-82	280.0	COG0500@1|root,COG2226@2|Bacteria,1GEHX@1117|Cyanobacteria	1117|Cyanobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_8434118_1	631362.Thi970DRAFT_02821	4.667e-177	567.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,1QR54@1224|Proteobacteria,1SMRM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MQ	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_8434118_22	926550.CLDAP_35170	6.298e-51	184.0	COG0346@1|root,COG0346@2|Bacteria,2G9TR@200795|Chloroflexi	200795|Chloroflexi	E	Glyoxalase-like domain	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
WLSH2_k127_8434118_32	1121405.dsmv_0329	6.148e-25	112.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WMZE@28221|Deltaproteobacteria,2MK3Y@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH2_k127_8434118_24	926569.ANT_22980	7.674e-48	186.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WLSH2_k127_8434118_33	459495.SPLC1_S203050	8.414e-21	95.0	COG1708@1|root,COG1708@2|Bacteria,1G9J2@1117|Cyanobacteria,1HCQI@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH2_k127_8434118_36	1147.D082_14650	1.338e-13	74.0	COG1895@1|root,COG1895@2|Bacteria,1G7UH@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
WLSH2_k127_8434118_35	1210884.HG799474_gene15133	2.85e-18	96.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS
WLSH2_k127_8434118_17	398527.Bphyt_4717	1.422e-67	250.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,2VWHM@28216|Betaproteobacteria,1K8SD@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8434118_38	356851.JOAN01000015_gene2693	0.0001924	52.0	COG0454@1|root,COG0456@2|Bacteria,2I41B@201174|Actinobacteria,4DCVF@85008|Micromonosporales	201174|Actinobacteria	K	Gcn5-related n-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_8434118_21	926550.CLDAP_38940	4.477e-59	216.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi	200795|Chloroflexi	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8434118_16	926569.ANT_17350	9.216e-68	242.0	COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
WLSH2_k127_8434118_37	1232410.KI421418_gene2194	1.306e-11	66.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,43S6Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
WLSH2_k127_8451111_22	862908.BMS_0329	1.41e-05	57.0	COG3307@1|root,COG3307@2|Bacteria,1NGAP@1224|Proteobacteria,42XF9@68525|delta/epsilon subdivisions,2MTE8@213481|Bdellovibrionales,2WSRN@28221|Deltaproteobacteria	213481|Bdellovibrionales	M	O-antigen ligase like membrane protein	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
WLSH2_k127_8451111_9	313612.L8106_11577	8.837e-49	186.0	28NSG@1|root,2ZBRE@2|Bacteria,1G640@1117|Cyanobacteria,1HEN5@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
WLSH2_k127_8451111_8	56780.SYN_01139	1.764e-52	205.0	COG0125@1|root,COG0125@2|Bacteria,1RA0K@1224|Proteobacteria	1224|Proteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8451111_23	1284352.AOIG01000016_gene4015	1.92e-05	56.0	COG2334@1|root,COG2334@2|Bacteria,1V3WG@1239|Firmicutes,4HI9X@91061|Bacilli,26UHX@186822|Paenibacillaceae	91061|Bacilli	S	Aminoglycoside phosphotransferase	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
WLSH2_k127_8451111_11	357808.RoseRS_2380	1.883e-45	179.0	COG0297@1|root,COG0297@2|Bacteria,2GBMD@200795|Chloroflexi,37794@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH2_k127_8451111_3	1385935.N836_19200	3.585e-78	276.0	COG0438@1|root,COG0438@2|Bacteria,1G1ED@1117|Cyanobacteria,1HH55@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WLSH2_k127_8451111_14	1429046.RR21198_5454	6.285e-28	126.0	COG0438@1|root,COG0438@2|Bacteria,2HQQW@201174|Actinobacteria,4G6SU@85025|Nocardiaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
WLSH2_k127_8451111_0	1198452.Jab_1c19290	1.842e-165	531.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VMX7@28216|Betaproteobacteria,478MA@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	UDP binding domain	algD	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WLSH2_k127_8451111_5	479434.Sthe_1132	2.113e-65	239.0	COG0297@1|root,COG0438@1|root,COG0726@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,COG0726@2|Bacteria,2G8HZ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WLSH2_k127_8451111_15	929556.Solca_2701	3.017e-18	99.0	COG1649@1|root,COG1649@2|Bacteria,4NI9V@976|Bacteroidetes,1IPVJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
WLSH2_k127_8451111_20	1278304.JAFR01000012_gene755	2.161e-06	61.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
WLSH2_k127_8451111_6	1318628.MARLIPOL_08264	1.999e-57	216.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,1SH3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8451111_1	338966.Ppro_2169	2.345e-117	389.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
WLSH2_k127_8451111_21	42256.RradSPS_0666	1.123e-05	50.0	COG2348@1|root,COG2348@2|Bacteria,2GJUD@201174|Actinobacteria	201174|Actinobacteria	V	Methicillin resistance protein	femX	-	2.3.2.10	ko:K05363,ko:K18354	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	R08779	RC00055,RC00096	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	-	-	-	FemAB
WLSH2_k127_8451111_18	697281.Mahau_2220	3.527e-09	61.0	COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,24AU8@186801|Clostridia,42F0P@68295|Thermoanaerobacterales	186801|Clostridia	V	FemAB family	femX	-	2.3.2.10,2.3.2.16	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	-	R08776,R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
WLSH2_k127_8451111_16	498761.HM1_1069	3.496e-13	72.0	COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,24AU8@186801|Clostridia	186801|Clostridia	V	Methicillin resistance protein	femX	-	2.3.2.10,2.3.2.16	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	-	R08776,R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
WLSH2_k127_8451111_2	1382359.JIAL01000001_gene938	5.648e-80	281.0	COG0438@1|root,COG0438@2|Bacteria,3Y6T4@57723|Acidobacteria,2JMK3@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
WLSH2_k127_8451111_4	309801.trd_0274	1.668e-73	263.0	COG5438@1|root,COG5438@2|Bacteria	2|Bacteria	S	YibE/F-like protein	yibE	-	-	-	-	-	-	-	-	-	-	-	YibE_F
WLSH2_k127_8451111_7	926569.ANT_13140	3.86e-56	202.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_8451111_12	926569.ANT_13160	5.161e-33	141.0	COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WLSH2_k127_8451111_10	309801.trd_1743	9.623e-48	185.0	COG4927@1|root,COG4927@2|Bacteria,2GA59@200795|Chloroflexi,27ZAW@189775|Thermomicrobia	189775|Thermomicrobia	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
WLSH2_k127_8451111_13	243164.DET0063	4.275e-29	133.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_8462998_4	926550.CLDAP_18740	6.582e-78	267.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WLSH2_k127_8462998_8	102129.Lepto7375DRAFT_7035	1.392e-44	188.0	COG0642@1|root,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
WLSH2_k127_8462998_3	706587.Desti_5093	1.346e-88	333.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_8462998_11	1123023.JIAI01000002_gene5619	4.132e-27	130.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4DZGK@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PAS_4
WLSH2_k127_8462998_6	357808.RoseRS_3061	3.958e-74	281.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,2GBT4@200795|Chloroflexi,376J7@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4
WLSH2_k127_8462998_1	706587.Desti_5093	3.108e-117	427.0	COG2202@1|root,COG3290@1|root,COG3829@1|root,COG4251@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CQ0@68525|delta/epsilon subdivisions,2X7X9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
WLSH2_k127_8462998_2	926569.ANT_03630	1.225e-104	348.0	COG5322@1|root,COG5322@2|Bacteria,2G8N0@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
WLSH2_k127_8462998_7	926569.ANT_03640	1.609e-60	221.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WLSH2_k127_8462998_9	926569.ANT_03650	1.927e-39	155.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WLSH2_k127_8462998_13	926569.ANT_20880	2.74e-06	55.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_8462998_10	469371.Tbis_3519	1.364e-34	139.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4DXV2@85010|Pseudonocardiales	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_8462998_5	926569.ANT_29790	1.071e-76	263.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
WLSH2_k127_8462998_0	926550.CLDAP_13750	3.725e-272	872.0	COG1404@1|root,COG1404@2|Bacteria,2G7GP@200795|Chloroflexi	200795|Chloroflexi	M	LPXTG-motif cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
WLSH2_k127_8462998_12	926550.CLDAP_13740	6.436e-23	100.0	2DRD4@1|root,33B9X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8491640_11	926569.ANT_19370	4.796e-82	285.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WLSH2_k127_8491640_8	383372.Rcas_3156	1.154e-99	335.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8491640_15	368407.Memar_2468	6.728e-46	179.0	COG2208@1|root,arCOG06893@2157|Archaea,2Y35A@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	5TM-5TMR_LYT,SpoIIE
WLSH2_k127_8491640_14	926569.ANT_05350	9.214e-54	198.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
WLSH2_k127_8491640_13	1158338.JNLJ01000001_gene956	2.705e-54	200.0	COG0175@1|root,COG0175@2|Bacteria,2G4VI@200783|Aquificae	200783|Aquificae	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
WLSH2_k127_8491640_2	926569.ANT_05360	3.182e-237	744.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
WLSH2_k127_8491640_10	926569.ANT_25840	4.619e-91	308.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
WLSH2_k127_8491640_5	926569.ANT_25850	1.803e-112	375.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_8491640_6	926569.ANT_24710	1.546e-107	351.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
WLSH2_k127_8491640_18	1450694.BTS2_3923	1.105e-13	78.0	COG1595@1|root,COG1595@2|Bacteria,1VCHT@1239|Firmicutes,4HX1M@91061|Bacilli,1ZH9M@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_8491640_0	926569.ANT_25290	0.0	1457.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WLSH2_k127_8491640_4	926569.ANT_05570	2.752e-122	401.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
WLSH2_k127_8491640_1	316274.Haur_4105	0.0	1185.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,374T1@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WLSH2_k127_8491640_9	316274.Haur_3739	7.193e-92	332.0	COG0457@1|root,COG1396@1|root,COG3903@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3903@2|Bacteria,2G64X@200795|Chloroflexi,376A5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31,NB-ARC,TPR_12
WLSH2_k127_8491640_7	525904.Tter_1978	1.69e-102	340.0	COG1402@1|root,COG1402@2|Bacteria,2NRPM@2323|unclassified Bacteria	2|Bacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WLSH2_k127_8491640_16	1499967.BAYZ01000184_gene4613	1.226e-31	125.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
WLSH2_k127_8491640_3	926569.ANT_29800	6.316e-211	664.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH2_k127_8491640_19	1476876.JOJO01000044_gene1244	3.038e-13	72.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_8530530_0	653733.Selin_2559	0.0	1236.0	COG0376@1|root,COG0376@2|Bacteria	2|Bacteria	P	catalase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
WLSH2_k127_8530530_6	1054213.HMPREF9946_03971	7.796e-05	47.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,2TSG9@28211|Alphaproteobacteria,2JPIY@204441|Rhodospirillales	204441|Rhodospirillales	P	Catalase	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
WLSH2_k127_8530530_4	1122132.AQYH01000008_gene2379	2.353e-10	61.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,2TSG9@28211|Alphaproteobacteria,4B9YW@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	serves to protect cells from the toxic effects of hydrogen peroxide	katA	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
WLSH2_k127_8530530_1	686340.Metal_0046	1.095e-179	568.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,1XF21@135618|Methylococcales	135618|Methylococcales	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WLSH2_k127_8530530_2	264732.Moth_2213	6.36e-24	108.0	COG4871@1|root,COG4871@2|Bacteria,1V7YF@1239|Firmicutes,24KYS@186801|Clostridia,42HHR@68295|Thermoanaerobacterales	186801|Clostridia	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS
WLSH2_k127_8530530_3	85643.Tmz1t_1856	7.749e-22	97.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VU78@28216|Betaproteobacteria,2KX1D@206389|Rhodocyclales	206389|Rhodocyclales	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WLSH2_k127_8530530_5	595494.Tola_1002	1.591e-05	47.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1S0YQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WLSH2_k127_8535685_1	207954.MED92_10314	1.067e-09	66.0	arCOG09511@1|root,2Z9DH@2|Bacteria,1MXRV@1224|Proteobacteria,1SEJ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM FRG domain	-	-	-	-	-	-	-	-	-	-	-	-	FRG
WLSH2_k127_8535685_0	530564.Psta_0774	3.11e-14	78.0	arCOG09511@1|root,30JF8@2|Bacteria,2J49H@203682|Planctomycetes	203682|Planctomycetes	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
WLSH2_k127_8538754_44	926550.CLDAP_32470	5.293e-99	345.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH2_k127_8538754_4	926569.ANT_19970	0.0	1033.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WLSH2_k127_8538754_72	1321778.HMPREF1982_01457	2.627e-48	181.0	2BZS9@1|root,2ZC3V@2|Bacteria,1V250@1239|Firmicutes,24EXQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_8538754_34	316274.Haur_4997	1.311e-114	378.0	COG1092@1|root,COG1092@2|Bacteria,2G7Y9@200795|Chloroflexi,3767A@32061|Chloroflexia	32061|Chloroflexia	H	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WLSH2_k127_8538754_77	1347342.BN863_17600	5.619e-42	157.0	COG3602@1|root,COG3602@2|Bacteria,4NQ4T@976|Bacteroidetes,1I2YS@117743|Flavobacteriia	976|Bacteroidetes	S	ACT domain	-	-	-	ko:K09964	-	-	-	-	ko00000	-	-	-	ACT_3,ACT_7
WLSH2_k127_8538754_49	485913.Krac_10180	9.45e-89	306.0	COG1801@1|root,COG1801@2|Bacteria,2G721@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WLSH2_k127_8538754_87	1267533.KB906733_gene2843	4.191e-26	115.0	COG2844@1|root,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
WLSH2_k127_8538754_70	1408422.JHYF01000015_gene325	7.833e-49	177.0	COG0251@1|root,COG0251@2|Bacteria,1V6HQ@1239|Firmicutes,25DSM@186801|Clostridia,36UEF@31979|Clostridiaceae	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WLSH2_k127_8538754_41	1173028.ANKO01000139_gene671	4.52e-105	355.0	COG1502@1|root,COG1502@2|Bacteria,1G01I@1117|Cyanobacteria,1H79E@1150|Oscillatoriales	2|Bacteria	I	TIGRFAM Competence protein ComEA, helix-hairpin-helix	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
WLSH2_k127_8538754_59	1122978.AUFP01000009_gene46	4.324e-77	269.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WLSH2_k127_8538754_89	926569.ANT_16980	9.283e-21	93.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WLSH2_k127_8538754_74	1396.DJ87_2170	7.944e-45	167.0	COG0494@1|root,COG0494@2|Bacteria,1VFWX@1239|Firmicutes,4HY7G@91061|Bacilli	91061|Bacilli	L	NUDIX domain	-	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
WLSH2_k127_8538754_53	926569.ANT_16730	1.827e-86	291.0	COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi	200795|Chloroflexi	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
WLSH2_k127_8538754_48	926569.ANT_16740	2.139e-96	327.0	COG1226@1|root,COG1226@2|Bacteria,2G7EI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM TrkA-N domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,TrkA_N
WLSH2_k127_8538754_85	926569.ANT_16750	2.201e-31	128.0	COG0125@1|root,COG0125@2|Bacteria,2GBP3@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8538754_61	357808.RoseRS_0293	1.16e-71	261.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WLSH2_k127_8538754_29	926569.ANT_16760	4.108e-136	448.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH2_k127_8538754_36	926569.ANT_16770	9.159e-114	374.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH2_k127_8538754_97	1280948.HY36_06410	0.0003787	53.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TU94@28211|Alphaproteobacteria,43WGZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs	fabH_2	-	2.3.1.207	ko:K16872	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C
WLSH2_k127_8538754_1	926569.ANT_17590	0.0	1326.0	COG3459@1|root,COG3459@2|Bacteria,2G9NQ@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyltransferase 36 associated	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8538754_18	926550.CLDAP_00330	8.281e-185	587.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WLSH2_k127_8538754_68	867845.KI911784_gene2744	4.051e-52	195.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
WLSH2_k127_8538754_10	1291050.JAGE01000001_gene2731	4.358e-203	659.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3WGK9@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyltransferase family 36	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
WLSH2_k127_8538754_3	1122963.AUHB01000001_gene328	0.0	1220.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,36Y2W@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	ndvB	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
WLSH2_k127_8538754_58	1487953.JMKF01000043_gene2591	1.879e-78	278.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
WLSH2_k127_8538754_6	1521187.JPIM01000003_gene3021	3.64e-283	895.0	COG1472@1|root,COG1472@2|Bacteria,2G639@200795|Chloroflexi,374XN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
WLSH2_k127_8538754_71	293826.Amet_4184	1.706e-48	183.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,24IMA@186801|Clostridia,36G15@31979|Clostridiaceae	186801|Clostridia	G	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
WLSH2_k127_8538754_50	335541.Swol_1899	1.511e-87	303.0	COG3934@1|root,COG3934@2|Bacteria,1UEWM@1239|Firmicutes,24AQC@186801|Clostridia,42KI0@68298|Syntrophomonadaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42M
WLSH2_k127_8538754_20	316274.Haur_0891	1.965e-179	567.0	COG2152@1|root,COG2152@2|Bacteria,2G6ZE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosidase PH1107-related	-	-	2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340	ko:K18785,ko:K20885	-	-	R10811,R10829,R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
WLSH2_k127_8538754_65	1150864.MILUP08_43481	2.103e-65	238.0	COG3325@1|root,COG3325@2|Bacteria,2I8CE@201174|Actinobacteria,4DCJN@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Glyco_hydro_75,RicinB_lectin_2,Ricin_B_lectin
WLSH2_k127_8538754_52	926569.ANT_11070	5.862e-87	301.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WLSH2_k127_8538754_22	926569.ANT_11080	5.716e-167	536.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WLSH2_k127_8538754_38	326427.Cagg_1688	4.551e-110	366.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi,37780@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH2_k127_8538754_35	926550.CLDAP_13300	4.611e-114	376.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
WLSH2_k127_8538754_25	926550.CLDAP_13310	1.312e-153	499.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WLSH2_k127_8538754_55	926550.CLDAP_13320	1.996e-85	294.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WLSH2_k127_8538754_33	357808.RoseRS_0043	2.559e-125	415.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,37580@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
WLSH2_k127_8538754_21	936574.HMPREF1508_1805	8.192e-171	550.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
WLSH2_k127_8538754_60	72019.SARC_01424T0	7.471e-73	251.0	COG0138@1|root,KOG2555@2759|Eukaryota,38H8U@33154|Opisthokonta	33154|Opisthokonta	F	IMP cyclohydrolase activity	ATIC	GO:0000003,GO:0003006,GO:0003360,GO:0003674,GO:0003824,GO:0003937,GO:0004643,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006760,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007049,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0009058,GO:0009060,GO:0009108,GO:0009116,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009235,GO:0009259,GO:0009260,GO:0009396,GO:0009611,GO:0009653,GO:0009987,GO:0010035,GO:0015980,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0019953,GO:0021537,GO:0021543,GO:0021549,GO:0021987,GO:0022037,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0030900,GO:0030902,GO:0031099,GO:0031100,GO:0032501,GO:0032502,GO:0032505,GO:0033013,GO:0034293,GO:0034641,GO:0034654,GO:0042060,GO:0042221,GO:0042398,GO:0042558,GO:0042559,GO:0042802,GO:0042803,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045333,GO:0046040,GO:0046390,GO:0046394,GO:0046452,GO:0046483,GO:0046653,GO:0046654,GO:0046983,GO:0048468,GO:0048513,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051186,GO:0051188,GO:0051321,GO:0051704,GO:0055086,GO:0055114,GO:0060322,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903046	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WLSH2_k127_8538754_64	1313172.YM304_23660	1.756e-66	232.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4CNS4@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
WLSH2_k127_8538754_24	573061.Clocel_3660	8.845e-164	523.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,36DHZ@31979|Clostridiaceae	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
WLSH2_k127_8538754_32	243275.TDE_1266	2.815e-127	415.0	COG0150@1|root,COG0150@2|Bacteria,2J5AP@203691|Spirochaetes	203691|Spirochaetes	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WLSH2_k127_8538754_27	1392501.JIAC01000001_gene1096	9.446e-149	484.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WLSH2_k127_8538754_19	1313172.YM304_23690	1.585e-184	588.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CMWP@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
WLSH2_k127_8538754_76	387631.Asulf_02162	1.291e-42	162.0	COG0041@1|root,arCOG02464@2157|Archaea,2XX7E@28890|Euryarchaeota,24696@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WLSH2_k127_8538754_28	221027.JO40_07350	2.598e-139	449.0	COG0152@1|root,COG0152@2|Bacteria,2J6XZ@203691|Spirochaetes	203691|Spirochaetes	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WLSH2_k127_8538754_56	243275.TDE_1405	1.547e-83	284.0	COG0047@1|root,COG0047@2|Bacteria,2J8JD@203691|Spirochaetes	203691|Spirochaetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	-	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WLSH2_k127_8538754_5	221027.JO40_12895	2.413e-291	921.0	COG0046@1|root,COG0046@2|Bacteria,2J66J@203691|Spirochaetes	203691|Spirochaetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
WLSH2_k127_8538754_2	926550.CLDAP_31970	0.0	1244.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WLSH2_k127_8538754_81	557598.LHK_01436	4.511e-39	152.0	COG3760@1|root,COG3760@2|Bacteria,1RDIG@1224|Proteobacteria,2VV7U@28216|Betaproteobacteria,2KT06@206351|Neisseriales	206351|Neisseriales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WLSH2_k127_8538754_63	15368.BRADI5G21040.1	5.438e-68	256.0	COG0153@1|root,KOG0631@2759|Eukaryota,37KN0@33090|Viridiplantae,3GHHX@35493|Streptophyta,3KNR5@4447|Liliopsida,3I3QA@38820|Poales	35493|Streptophyta	G	Galactokinase galactose-binding signature	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019586,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046396,GO:0046835,GO:0047912,GO:0071704	2.7.1.44	ko:K18677,ko:K19347	ko00520,map00520	-	R01980	RC00002,RC00078	ko00000,ko00001,ko01000,ko03036	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WLSH2_k127_8538754_88	1041930.Mtc_2013	1.594e-25	123.0	COG1208@1|root,arCOG00668@2157|Archaea,2Y87G@28890|Euryarchaeota,2N9FU@224756|Methanomicrobia	224756|Methanomicrobia	M	transferase hexapeptide repeat containing protein	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WLSH2_k127_8538754_91	926569.ANT_11070	3.843e-10	64.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WLSH2_k127_8538754_78	63737.Npun_F3179	7.043e-41	158.0	COG1309@1|root,COG1309@2|Bacteria,1G61G@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
WLSH2_k127_8538754_66	512565.AMIS_22440	1.278e-64	228.0	COG0001@1|root,COG0235@1|root,COG0001@2|Bacteria,COG0235@2|Bacteria,2IC57@201174|Actinobacteria,4DBUG@85008|Micromonosporales	201174|Actinobacteria	GH	Class II Aldolase and Adducin N-terminal domain	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aldolase_II,Aminotran_3
WLSH2_k127_8538754_9	1869.MB27_11505	4.316e-219	692.0	COG0001@1|root,COG0235@1|root,COG0001@2|Bacteria,COG0235@2|Bacteria,2IC57@201174|Actinobacteria,4DBUG@85008|Micromonosporales	201174|Actinobacteria	GH	Class II Aldolase and Adducin N-terminal domain	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aldolase_II,Aminotran_3
WLSH2_k127_8538754_16	1220582.RRU01S_01_00210	2.443e-188	602.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2TR7P@28211|Alphaproteobacteria,4BCCU@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	FGGY family of carbohydrate kinases, C-terminal domain	xylBch	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WLSH2_k127_8538754_13	324057.Pjdr2_2837	4.576e-197	623.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,274KS@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	lacG	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657	3.2.1.21,3.2.1.85,3.2.1.86	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	-	R00026,R00839,R02558,R02887,R02985,R03256,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
WLSH2_k127_8538754_8	926569.ANT_29780	2.678e-228	721.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	bgaC	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
WLSH2_k127_8538754_7	522306.CAP2UW1_3003	1.976e-245	778.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2VJYR@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5110,Glyco_hydro_31
WLSH2_k127_8538754_96	1144275.COCOR_04613	8.97e-05	53.0	COG2220@1|root,COG2220@2|Bacteria,1R4BX@1224|Proteobacteria	1224|Proteobacteria	K	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
WLSH2_k127_8538754_75	1499967.BAYZ01000095_gene4292	3.614e-44	172.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73	ko:K00852,ko:K00856,ko:K10710,ko:K22026	ko00030,ko00230,ko00240,ko01100,map00030,map00230,map00240,map01100	-	R00185,R00513,R01051,R01131,R01228,R02750,R08124	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WLSH2_k127_8538754_43	643648.Slip_0683	2.794e-99	334.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia,42KBW@68298|Syntrophomonadaceae	186801|Clostridia	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
WLSH2_k127_8538754_69	706587.Desti_4215	8.005e-50	185.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria	1224|Proteobacteria	P	phosphate transport regulator (Distant homolog of PhoU)	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
WLSH2_k127_8538754_84	237368.SCABRO_00336	1.836e-31	141.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
WLSH2_k127_8538754_82	1235797.C816_00541	3.995e-37	159.0	COG1011@1|root,COG1011@2|Bacteria,1V3M1@1239|Firmicutes	1239|Firmicutes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WLSH2_k127_8538754_80	391937.NA2_02144	4.954e-40	167.0	COG1011@1|root,COG1011@2|Bacteria	391937.NA2_02144|-	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8538754_79	1125699.HMPREF9194_00556	2.032e-40	168.0	COG1011@1|root,COG1011@2|Bacteria,2J8W7@203691|Spirochaetes	203691|Spirochaetes	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WLSH2_k127_8538754_73	391937.NA2_02149	4.67e-46	182.0	COG1840@1|root,COG1840@2|Bacteria,1R6JS@1224|Proteobacteria,2TV74@28211|Alphaproteobacteria,43RGM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
WLSH2_k127_8538754_39	391937.NA2_02154	2.908e-107	358.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,43P1A@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
WLSH2_k127_8538754_26	1125701.HMPREF1221_00389	4.439e-153	504.0	COG1178@1|root,COG1178@2|Bacteria,2J5J4@203691|Spirochaetes	203691|Spirochaetes	P	ABC transporter permease	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
WLSH2_k127_8538754_86	1122919.KB905566_gene2729	1.6e-30	132.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,4HG9U@91061|Bacilli,26R67@186822|Paenibacillaceae	91061|Bacilli	K	RpiR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
WLSH2_k127_8538754_45	525904.Tter_0098	7.54e-99	338.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
WLSH2_k127_8538754_83	1235797.C816_00541	6.936e-37	149.0	COG1011@1|root,COG1011@2|Bacteria,1V3M1@1239|Firmicutes	1239|Firmicutes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WLSH2_k127_8538754_92	552396.HMPREF0863_00738	1.223e-09	70.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,3VNZC@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WLSH2_k127_8538754_95	743722.Sph21_4665	8.099e-05	55.0	COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,1IRQM@117747|Sphingobacteriia	976|Bacteroidetes	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WLSH2_k127_8538754_30	1123242.JH636434_gene5048	1.496e-129	425.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
WLSH2_k127_8538754_15	1226322.HMPREF1545_02308	1.448e-193	617.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,2N7Z2@216572|Oscillospiraceae	186801|Clostridia	G	BPG-independent PGAM N-terminus (iPGM_N)	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
WLSH2_k127_8538754_62	1226322.HMPREF1545_03025	4.876e-68	241.0	COG1011@1|root,COG1011@2|Bacteria,1UX48@1239|Firmicutes,257UK@186801|Clostridia,2N82N@216572|Oscillospiraceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WLSH2_k127_8538754_57	1235797.C816_00541	1.345e-79	272.0	COG1011@1|root,COG1011@2|Bacteria,1V3M1@1239|Firmicutes	1239|Firmicutes	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WLSH2_k127_8538754_54	1267535.KB906767_gene2354	9.486e-86	295.0	COG1609@1|root,COG1609@2|Bacteria,3Y6K5@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WLSH2_k127_8538754_17	1128421.JAGA01000002_gene1491	3.398e-188	600.0	2BXG3@1|root,2Z82R@2|Bacteria	2|Bacteria	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
WLSH2_k127_8538754_46	403833.Pmob_0444	7.495e-98	326.0	COG1028@1|root,COG1028@2|Bacteria,2GDVT@200918|Thermotogae	200918|Thermotogae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WLSH2_k127_8538754_31	1128421.JAGA01000002_gene1496	6.64e-128	422.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
WLSH2_k127_8538754_12	926569.ANT_01430	2.585e-197	625.0	COG0362@1|root,COG0362@2|Bacteria,2GBID@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WLSH2_k127_8538754_14	234267.Acid_7084	1.208e-195	615.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WLSH2_k127_8538754_67	309799.DICTH_0521	1.382e-54	204.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	tdh	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_8538754_42	926550.CLDAP_26120	6.903e-105	347.0	COG1082@1|root,COG1082@2|Bacteria,2G9NU@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
WLSH2_k127_8538754_40	697281.Mahau_2741	2.411e-106	355.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,24B6F@186801|Clostridia,42I6E@68295|Thermoanaerobacterales	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	Cupin_5,GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_8538754_23	1209989.TepiRe1_0710	9.237e-167	531.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WLSH2_k127_8538754_11	1121335.Clst_0986	2.549e-198	623.0	COG1063@1|root,COG1063@2|Bacteria,1UY6M@1239|Firmicutes,24AX0@186801|Clostridia,3WP0Z@541000|Ruminococcaceae	186801|Clostridia	E	Zinc-binding dehydrogenase	-	-	-	ko:K22231	ko00562,map00562	-	R11770	-	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_8538754_51	573413.Spirs_3462	3.141e-87	300.0	COG1082@1|root,COG1082@2|Bacteria,2J8EP@203691|Spirochaetes	203691|Spirochaetes	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
WLSH2_k127_8538754_94	1304874.JAFY01000002_gene682	2.563e-07	53.0	COG2515@1|root,COG2515@2|Bacteria,3TB8Y@508458|Synergistetes	508458|Synergistetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
WLSH2_k127_8538754_0	926550.CLDAP_00560	0.0	2068.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WLSH2_k127_8538754_90	399550.Smar_0666	1.795e-10	66.0	COG1977@1|root,arCOG00536@2157|Archaea	2157|Archaea	H	Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH2_k127_8538754_37	96561.Dole_0225	1.025e-112	383.0	COG0318@1|root,COG0318@2|Bacteria,1NRF1@1224|Proteobacteria,42ZBQ@68525|delta/epsilon subdivisions,2WUGE@28221|Deltaproteobacteria,2MMKI@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_8618209_5	926569.ANT_05220	9.053e-63	219.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WLSH2_k127_8618209_2	926569.ANT_10690	1.685e-92	308.0	COG1402@1|root,COG1402@2|Bacteria,2G7B0@200795|Chloroflexi	200795|Chloroflexi	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WLSH2_k127_8618209_7	521003.COLINT_02757	8.456e-23	101.0	COG0640@1|root,COG0640@2|Bacteria,2GUDD@201174|Actinobacteria,4CW8F@84998|Coriobacteriia	84998|Coriobacteriia	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WLSH2_k127_8618209_4	215803.DB30_8893	5.284e-67	239.0	COG0300@1|root,COG0300@2|Bacteria,1R5VP@1224|Proteobacteria,430U9@68525|delta/epsilon subdivisions,2WW0M@28221|Deltaproteobacteria,2YXV8@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_8618209_8	1218075.BAYA01000005_gene1930	1.058e-15	85.0	COG2020@1|root,COG2020@2|Bacteria,1MXP9@1224|Proteobacteria,2VZ1R@28216|Betaproteobacteria,1K6RN@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
WLSH2_k127_8618209_3	484770.UFO1_1182	3.916e-89	301.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,4H387@909932|Negativicutes	909932|Negativicutes	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_8618209_1	484770.UFO1_1183	2.145e-152	510.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_8618209_9	1173021.ALWA01000020_gene158	1.252e-14	86.0	COG0845@1|root,COG0845@2|Bacteria,1G01U@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH2_k127_8618209_10	1122985.HMPREF1991_02002	1.123e-05	50.0	COG3315@1|root,COG3315@2|Bacteria,4NI9Z@976|Bacteroidetes	976|Bacteroidetes	Q	Psort location Cytoplasmic, score	tcmP	-	-	-	-	-	-	-	-	-	-	-	LCM
WLSH2_k127_8618209_6	1009370.ALO_07578	2.452e-47	181.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,4H4K1@909932|Negativicutes	909932|Negativicutes	H	O-Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
WLSH2_k127_8618209_0	994573.T472_0206750	3.635e-163	531.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,36DDM@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH2_k127_8746364_35	386456.JQKN01000008_gene1621	3.453e-07	61.0	arCOG03042@1|root,arCOG03042@2157|Archaea	2157|Archaea	KLT	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
WLSH2_k127_8746364_5	926569.ANT_08950	4.171e-132	450.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
WLSH2_k127_8746364_34	1230341.MJ3_03437	3.021e-09	68.0	COG0726@1|root,COG1388@1|root,COG0726@2|Bacteria,COG1388@2|Bacteria,1UZ7Q@1239|Firmicutes,4IPRX@91061|Bacilli	91061|Bacilli	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
WLSH2_k127_8746364_15	1382356.JQMP01000003_gene1423	7.816e-51	201.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WLSH2_k127_8746364_11	497965.Cyan7822_0461	2.331e-62	218.0	COG4914@1|root,COG4914@2|Bacteria,1GE0D@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8746364_7	926569.ANT_08920	4.297e-115	378.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WLSH2_k127_8746364_8	926569.ANT_08910	1.574e-97	335.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi	200795|Chloroflexi	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
WLSH2_k127_8746364_14	926569.ANT_02700	1.047e-52	191.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
WLSH2_k127_8746364_31	926569.ANT_27460	9.785e-14	76.0	COG2919@1|root,COG2919@2|Bacteria,2G9Q3@200795|Chloroflexi	200795|Chloroflexi	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
WLSH2_k127_8746364_3	926550.CLDAP_31520	3.718e-155	501.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi	200795|Chloroflexi	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WLSH2_k127_8746364_27	555088.DealDRAFT_1165	1.148e-16	88.0	COG0664@1|root,COG0664@2|Bacteria,1V8FC@1239|Firmicutes,25MZJ@186801|Clostridia,42KUQ@68298|Syntrophomonadaceae	186801|Clostridia	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_8746364_30	178306.PAE3607	3.726e-14	80.0	arCOG07069@1|root,arCOG07069@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8746364_22	410359.Pcal_1023	2.451e-34	149.0	arCOG07070@1|root,arCOG07070@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8746364_26	756067.MicvaDRAFT_3323	6.959e-21	105.0	COG1262@1|root,COG1262@2|Bacteria,1G0FF@1117|Cyanobacteria,1H8UZ@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
WLSH2_k127_8746364_18	374847.Kcr_0887	1.367e-41	164.0	COG0109@1|root,arCOG00479@2157|Archaea	2157|Archaea	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
WLSH2_k127_8746364_29	178306.PAE3607	1.025e-14	85.0	arCOG07069@1|root,arCOG07069@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8746364_6	593750.Metfor_2818	2.851e-121	393.0	COG0863@1|root,arCOG00115@2157|Archaea,2XT30@28890|Euryarchaeota	28890|Euryarchaeota	L	COG0863 DNA modification methylase	-	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
WLSH2_k127_8746364_23	926569.ANT_17840	2.465e-33	131.0	COG0375@1|root,COG0375@2|Bacteria,2G7H5@200795|Chloroflexi	200795|Chloroflexi	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
WLSH2_k127_8746364_9	926569.ANT_17850	7.906e-81	274.0	COG0378@1|root,COG0378@2|Bacteria,2G6EP@200795|Chloroflexi	200795|Chloroflexi	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K03189,ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
WLSH2_k127_8746364_0	926569.ANT_17860	5.245e-270	854.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
WLSH2_k127_8746364_25	926569.ANT_17870	1.027e-26	111.0	COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi	200795|Chloroflexi	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
WLSH2_k127_8746364_1	926569.ANT_17880	6.016e-170	541.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi	200795|Chloroflexi	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
WLSH2_k127_8746364_4	926569.ANT_17890	1.354e-133	434.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi	200795|Chloroflexi	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
WLSH2_k127_8746364_24	1038860.AXAP01000001_gene6469	6.288e-27	129.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3JTYC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,dCache_1
WLSH2_k127_8746364_17	1499967.BAYZ01000014_gene6352	1.982e-47	196.0	COG0642@1|root,COG2205@2|Bacteria	1499967.BAYZ01000014_gene6352|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8746364_16	316274.Haur_0818	2.613e-49	185.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_8746364_33	189426.PODO_20995	8.212e-10	70.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V0CQ@1239|Firmicutes,4HFH0@91061|Bacilli,26STT@186822|Paenibacillaceae	91061|Bacilli	T	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
WLSH2_k127_8746364_32	411483.FAEPRAA2165_01560	1.943e-11	75.0	COG0642@1|root,COG2205@2|Bacteria,1UK9G@1239|Firmicutes,25FRF@186801|Clostridia,3WRIN@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
WLSH2_k127_8746364_12	316274.Haur_1217	2.581e-58	224.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WLSH2_k127_8746364_13	316274.Haur_1217	5.8e-54	215.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WLSH2_k127_8746364_28	1121022.ABENE_06785	3.783e-15	91.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U7M5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WLSH2_k127_8746364_21	926569.ANT_11800	2.218e-36	160.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
WLSH2_k127_8746364_19	316274.Haur_1217	5e-39	169.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WLSH2_k127_8746364_10	316274.Haur_1217	1.332e-75	277.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WLSH2_k127_8746364_2	316274.Haur_1218	4.318e-157	504.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G66Y@200795|Chloroflexi,375PP@32061|Chloroflexia	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733,ko:K22010	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018,M00839	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	HATPase_c,HisKA,PALP,Response_reg
WLSH2_k127_8812277_20	1397284.AYMN01000004_gene2998	3.893e-11	72.0	2DC1F@1|root,2ZCE5@2|Bacteria,1RCQ9@1224|Proteobacteria,1S28C@1236|Gammaproteobacteria,400VF@613|Serratia	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
WLSH2_k127_8812277_19	158189.SpiBuddy_2602	2.614e-13	74.0	COG1545@1|root,COG1545@2|Bacteria,2JAEJ@203691|Spirochaetes	203691|Spirochaetes	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	-
WLSH2_k127_8812277_5	748727.CLJU_c23630	4.304e-142	461.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24FFI@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_8812277_14	748727.CLJU_c23640	1.055e-69	244.0	2ATRB@1|root,31JA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8812277_4	926569.ANT_05840	4.109e-166	526.0	COG1878@1|root,COG1878@2|Bacteria,2G8DE@200795|Chloroflexi	200795|Chloroflexi	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
WLSH2_k127_8812277_2	443254.Marpi_1683	2.855e-180	576.0	COG0074@1|root,COG0074@2|Bacteria,2GDXF@200918|Thermotogae	200918|Thermotogae	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
WLSH2_k127_8812277_6	1499967.BAYZ01000016_gene6505	7.788e-139	459.0	COG0074@1|root,COG0074@2|Bacteria,2NQBH@2323|unclassified Bacteria	2|Bacteria	C	CoA-ligase	sucD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009361,GO:0032991,GO:0042709,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:1902494	6.2.1.5	ko:K01902,ko:K02381	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
WLSH2_k127_8812277_0	926569.ANT_05790	0.0	1093.0	COG1529@1|root,COG1529@2|Bacteria,2G7M5@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_8812277_13	926569.ANT_05780	5.464e-70	241.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WLSH2_k127_8812277_9	926569.ANT_05770	3.45e-108	358.0	COG1319@1|root,COG1319@2|Bacteria,2G8QI@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
WLSH2_k127_8812277_17	867903.ThesuDRAFT_01376	1.575e-19	92.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,3WCXZ@538999|Clostridiales incertae sedis	186801|Clostridia	F	Permease family	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
WLSH2_k127_8812277_15	485913.Krac_3483	7.261e-53	190.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WLSH2_k127_8812277_18	357808.RoseRS_1377	9.336e-18	88.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi,3770T@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WLSH2_k127_8812277_1	880073.Calab_3450	1.438e-185	616.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
WLSH2_k127_8812277_12	1121374.KB891591_gene3472	5.986e-80	277.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
WLSH2_k127_8812277_7	1051632.TPY_0985	4.033e-121	398.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WCUJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WLSH2_k127_8812277_11	358681.BBR47_26460	8.429e-100	335.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,26QZ3@186822|Paenibacillaceae	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00566	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.2,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WLSH2_k127_8812277_10	1348338.ADILRU_2542	5.994e-102	339.0	COG1173@1|root,COG1173@2|Bacteria,2GNQ5@201174|Actinobacteria,4FP06@85023|Microbacteriaceae	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WLSH2_k127_8812277_8	29306.JOBE01000012_gene6479	9.845e-115	382.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria	201174|Actinobacteria	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_8812277_3	1348338.ADILRU_2544	2.263e-176	567.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria	201174|Actinobacteria	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_8812277_16	526225.Gobs_1678	7.759e-50	187.0	COG2909@1|root,COG2909@2|Bacteria,2I50W@201174|Actinobacteria,4EU8S@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
WLSH2_k127_8815716_21	118161.KB235922_gene2311	1.984e-85	298.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WLSH2_k127_8815716_30	485913.Krac_3036	8.25e-53	193.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudK	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0046872,GO:0052751	3.6.1.13	ko:K01515,ko:K12945	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iLF82_1304.LF82_1537,iNRG857_1313.NRG857_12310,iUTI89_1310.UTI89_C2793,ic_1306.c2994	NUDIX
WLSH2_k127_8815716_19	298653.Franean1_5217	7.634e-88	304.0	COG2110@1|root,COG2110@2|Bacteria,2IBAB@201174|Actinobacteria	201174|Actinobacteria	T	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
WLSH2_k127_8815716_23	926569.ANT_01360	1.195e-80	273.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi	200795|Chloroflexi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
WLSH2_k127_8815716_37	926569.ANT_01350	3.095e-36	140.0	COG0718@1|root,COG0718@2|Bacteria	2|Bacteria	S	YbaB/EbfC DNA-binding family	ybaB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	ko:K06187,ko:K09747	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	YbaB_DNA_bd
WLSH2_k127_8815716_7	926569.ANT_01340	4.164e-158	514.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WLSH2_k127_8815716_45	521011.Mpal_1970	1.796e-14	81.0	COG3291@1|root,arCOG02498@1|root,arCOG02526@1|root,arCOG02498@2157|Archaea,arCOG02510@2157|Archaea,arCOG02526@2157|Archaea,2Y30D@28890|Euryarchaeota,2NAGI@224756|Methanomicrobia	224756|Methanomicrobia	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	NosD,PKD
WLSH2_k127_8815716_15	926569.ANT_25030	8.237e-105	350.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WLSH2_k127_8815716_46	1303692.SFUL_3662	5.759e-11	69.0	COG1051@1|root,COG1051@2|Bacteria,2IFGP@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_8815716_34	671143.DAMO_2925	2.95e-40	151.0	COG1993@1|root,COG1993@2|Bacteria,2NPXF@2323|unclassified Bacteria	2|Bacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
WLSH2_k127_8815716_38	671143.DAMO_2926	1.56e-34	136.0	COG0239@1|root,COG0239@2|Bacteria,2NQ56@2323|unclassified Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
WLSH2_k127_8815716_17	316274.Haur_4582	5.812e-102	341.0	COG1230@1|root,COG1230@2|Bacteria,2G6FI@200795|Chloroflexi,37777@32061|Chloroflexia	32061|Chloroflexia	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
WLSH2_k127_8815716_42	1121456.ATVA01000012_gene2837	1.741e-24	105.0	COG0640@1|root,COG0640@2|Bacteria,1N8M7@1224|Proteobacteria,42U4R@68525|delta/epsilon subdivisions,2WQ3N@28221|Deltaproteobacteria,2MCI0@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM regulatory protein ArsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WLSH2_k127_8815716_8	926569.ANT_25040	1.981e-152	489.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi	200795|Chloroflexi	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH2_k127_8815716_0	926569.ANT_25050	9.69e-315	973.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WLSH2_k127_8815716_36	926569.ANT_25060	2.713e-36	144.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WLSH2_k127_8815716_13	926569.ANT_25070	2.588e-128	418.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
WLSH2_k127_8815716_3	926569.ANT_22580	6.212e-193	626.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
WLSH2_k127_8815716_16	926569.ANT_23650	2.428e-104	369.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
WLSH2_k127_8815716_4	926569.ANT_23640	6.985e-185	593.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
WLSH2_k127_8815716_20	326427.Cagg_1901	8.34e-88	303.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WLSH2_k127_8815716_24	926569.ANT_16140	5.752e-73	258.0	COG0524@1|root,COG0524@2|Bacteria,2G9QW@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WLSH2_k127_8815716_39	1047013.AQSP01000131_gene1797	9.019e-34	144.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WLSH2_k127_8815716_47	1391647.AVSV01000028_gene248	1.48e-09	63.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
WLSH2_k127_8815716_25	629773.AORY01000001_gene2284	4.734e-69	248.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,2K0QN@204457|Sphingomonadales	204457|Sphingomonadales	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WLSH2_k127_8815716_41	926569.ANT_04290	2.951e-27	122.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WLSH2_k127_8815716_26	479434.Sthe_1268	1.421e-61	228.0	COG4454@1|root,COG4454@2|Bacteria,2GBEQ@200795|Chloroflexi,27Z6N@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8815716_14	497964.CfE428DRAFT_0631	4.582e-107	378.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
WLSH2_k127_8815716_35	926550.CLDAP_11000	6.646e-39	147.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WLSH2_k127_8815716_43	926569.ANT_04290	9.004e-17	81.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WLSH2_k127_8815716_28	1345697.M493_05970	1.999e-55	224.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,1WF37@129337|Geobacillus	91061|Bacilli	KLT	Serine/Threonine protein kinases, catalytic domain	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_8815716_6	2002.JOEQ01000016_gene7347	1.712e-180	622.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
WLSH2_k127_8815716_48	926569.ANT_04290	2.544e-07	57.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WLSH2_k127_8815716_10	926550.CLDAP_11000	1.6e-146	471.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WLSH2_k127_8815716_11	926550.CLDAP_11010	1.82e-144	464.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WLSH2_k127_8815716_9	926550.CLDAP_11020	6.659e-151	490.0	COG1173@1|root,COG1173@2|Bacteria,2G841@200795|Chloroflexi	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
WLSH2_k127_8815716_12	926550.CLDAP_11030	6.223e-132	431.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_8815716_5	1121939.L861_22665	1.907e-181	601.0	COG0747@1|root,COG3889@1|root,COG0747@2|Bacteria,COG3889@2|Bacteria,1R6EI@1224|Proteobacteria,1SKRH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_8815716_2	1047013.AQSP01000070_gene34	2.883e-224	740.0	COG3292@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3920@2|Bacteria,2NNZT@2323|unclassified Bacteria	2|Bacteria	T	Two component regulator propeller	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,Reg_prop,Y_Y_Y
WLSH2_k127_8815716_32	266117.Rxyl_2810	2.292e-42	181.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WLSH2_k127_8815716_22	926569.ANT_08740	4.992e-84	286.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WLSH2_k127_8815716_29	357808.RoseRS_0452	4.879e-55	204.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi,377X2@32061|Chloroflexia	32061|Chloroflexia	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
WLSH2_k127_8815716_31	357808.RoseRS_0453	5.605e-51	186.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi,377X2@32061|Chloroflexia	32061|Chloroflexia	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
WLSH2_k127_8815716_18	324602.Caur_1435	4.184e-97	327.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WLSH2_k127_8815716_27	926569.ANT_26490	6.53e-61	221.0	COG0760@1|root,COG0760@2|Bacteria,2G9A4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
WLSH2_k127_8815716_1	926569.ANT_26670	1.446e-255	797.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WLSH2_k127_8815716_33	926569.ANT_26660	3.346e-41	154.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WLSH2_k127_8865455_2	926550.CLDAP_29050	1.072e-106	363.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WLSH2_k127_8865455_1	246197.MXAN_0895	8.703e-148	485.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,43BX1@68525|delta/epsilon subdivisions,2X77U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WLSH2_k127_8865455_3	926550.CLDAP_29060	3.053e-99	332.0	COG1562@1|root,COG1562@2|Bacteria,2G6KD@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Squalene phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WLSH2_k127_8865455_6	926550.CLDAP_15070	2.926e-60	217.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	M1-693	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
WLSH2_k127_8865455_7	929703.KE386491_gene2365	4.06e-58	211.0	COG2755@1|root,COG2755@2|Bacteria,4NNIC@976|Bacteroidetes,47PEW@768503|Cytophagia	976|Bacteroidetes	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WLSH2_k127_8865455_4	357808.RoseRS_0703	1.746e-97	331.0	COG1168@1|root,COG1168@2|Bacteria,2G614@200795|Chloroflexi,375GA@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase, class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_8865455_0	926569.ANT_04650	5.63e-245	764.0	COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
WLSH2_k127_8865455_10	926569.ANT_21400	4.461e-24	105.0	COG4737@1|root,COG4737@2|Bacteria	2|Bacteria	G	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
WLSH2_k127_8865455_9	926569.ANT_21410	1.655e-26	111.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
WLSH2_k127_8865455_5	1278073.MYSTI_00455	5.831e-67	234.0	COG1040@1|root,COG1040@2|Bacteria,1N668@1224|Proteobacteria,430SZ@68525|delta/epsilon subdivisions,2WVMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
WLSH2_k127_8865455_8	926569.ANT_04640	1.27e-52	192.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8888751_3	368407.Memar_0873	7.697e-09	63.0	arCOG06529@1|root,arCOG06529@2157|Archaea	2157|Archaea	S	Protein of unknown function (DUF3887)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DUF3887,Hydrolase_4
WLSH2_k127_8888751_1	485913.Krac_4912	1.157e-36	149.0	COG1670@1|root,COG1670@2|Bacteria,2G9F1@200795|Chloroflexi	200795|Chloroflexi	J	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
WLSH2_k127_8888751_0	566466.NOR53_2651	2.961e-75	261.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,1RNB3@1236|Gammaproteobacteria,1J9WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
WLSH2_k127_8888751_2	671143.DAMO_2920	1.983e-10	63.0	2DRSH@1|root,33CVS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8892559_0	243231.GSU1538	9.242e-134	437.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N38@68525|delta/epsilon subdivisions,2WK56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
WLSH2_k127_8892559_7	1121479.AUBS01000002_gene3634	3.158e-06	55.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1PPWK@1224|Proteobacteria,2TYY3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
WLSH2_k127_8892559_8	1196323.ALKF01000159_gene5136	0.0002224	46.0	2C95S@1|root,33HPC@2|Bacteria,1VJZ1@1239|Firmicutes,4I8KU@91061|Bacilli,2703Y@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
WLSH2_k127_8892559_6	290512.Paes_0654	9.202e-07	58.0	COG4194@1|root,COG4194@2|Bacteria,1FF6D@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
WLSH2_k127_8892559_5	1196324.A374_16914	9.643e-22	108.0	COG0846@1|root,COG0846@2|Bacteria,1VF69@1239|Firmicutes,4HXHS@91061|Bacilli	91061|Bacilli	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
WLSH2_k127_8892559_3	926569.ANT_05870	4.608e-54	196.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	pilL	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K02487,ko:K03407,ko:K03413,ko:K06596,ko:K11526,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507,M00508,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
WLSH2_k127_8892559_1	204669.Acid345_3113	4.069e-98	335.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WLSH2_k127_8892559_2	1408473.JHXO01000001_gene2059	7.666e-71	248.0	COG4221@1|root,COG4221@2|Bacteria	2|Bacteria	IQ	oxidoreductase activity	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	DUF4336,adh_short,adh_short_C2
WLSH2_k127_8892559_4	1385935.N836_20050	1.458e-46	170.0	COG1233@1|root,COG1233@2|Bacteria,1GCDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WLSH2_k127_8902084_3	1280664.AUIX01000002_gene514	9.46e-05	50.0	COG2227@1|root,COG2227@2|Bacteria,1UZF8@1239|Firmicutes	1239|Firmicutes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_8902084_0	211165.AJLN01000005_gene3823	1.371e-130	431.0	COG3385@1|root,COG3385@2|Bacteria,1GGJ4@1117|Cyanobacteria,1JJPW@1189|Stigonemataceae	1117|Cyanobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
WLSH2_k127_8902084_2	1121430.JMLG01000007_gene2546	5.474e-52	196.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,2612F@186807|Peptococcaceae	186801|Clostridia	HP	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
WLSH2_k127_8902084_1	871968.DESME_01185	3.517e-96	322.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,2605W@186807|Peptococcaceae	186801|Clostridia	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WLSH2_k127_8939816_6	1122176.KB903587_gene4434	8.915e-10	68.0	COG4242@1|root,COG4242@2|Bacteria,4NHDE@976|Bacteroidetes,1IWDD@117747|Sphingobacteriia	976|Bacteroidetes	PQ	Peptidase family S51	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WLSH2_k127_8939816_3	1444309.JAQG01000031_gene2895	4.382e-51	185.0	COG1051@1|root,COG1051@2|Bacteria,1V6D5@1239|Firmicutes,4HJTU@91061|Bacilli,26XD5@186822|Paenibacillaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_8939816_2	1184267.A11Q_488	1.06e-65	236.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2MTST@213481|Bdellovibrionales,2WQCC@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
WLSH2_k127_8939816_1	1047013.AQSP01000122_gene2256	7.159e-85	296.0	COG0624@1|root,COG0624@2|Bacteria,2NQWS@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M20/M25/M40	amaB	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WLSH2_k127_8939816_4	246197.MXAN_6602	3.42e-35	139.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
WLSH2_k127_8939816_7	635013.TherJR_0334	9.961e-10	64.0	2DCQ6@1|root,2ZEXE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8939816_0	1454004.AW11_00407	3.322e-123	407.0	COG0012@1|root,COG0012@2|Bacteria,1Q097@1224|Proteobacteria,2W504@28216|Betaproteobacteria	28216|Betaproteobacteria	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8939816_5	266117.Rxyl_2810	6.617e-26	119.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WLSH2_k127_8973304_19	926569.ANT_17610	1.513e-59	212.0	COG1611@1|root,COG1611@2|Bacteria,2G6P1@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WLSH2_k127_8973304_2	926550.CLDAP_19360	8.55e-306	959.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
WLSH2_k127_8973304_12	326427.Cagg_2505	3.32e-78	265.0	COG0225@1|root,COG0225@2|Bacteria,2G6JK@200795|Chloroflexi,375KD@32061|Chloroflexia	32061|Chloroflexia	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WLSH2_k127_8973304_35	324602.Caur_1913	2.307e-05	57.0	COG5617@1|root,COG5617@2|Bacteria,2GA8B@200795|Chloroflexi,374Y6@32061|Chloroflexia	32061|Chloroflexia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8973304_23	118166.JH976538_gene5111	3.043e-52	189.0	2AWZQ@1|root,31NXM@2|Bacteria,1G6ZZ@1117|Cyanobacteria,1HBW7@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8973304_5	335541.Swol_1787	5.933e-158	520.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42KH2@68298|Syntrophomonadaceae	186801|Clostridia	H	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WLSH2_k127_8973304_24	709986.Deima_0127	3.735e-51	191.0	COG3885@1|root,COG3885@2|Bacteria	2|Bacteria	S	ferrous iron binding	amrA	-	-	ko:K06990,ko:K15755	ko00621,ko01100,ko01120,ko01220,map00621,map01100,map01120,map01220	M00544	R05415	RC01306	br01602,ko00000,ko00001,ko00002,ko01000,ko04812	-	-	-	AMMECR1,LigB
WLSH2_k127_8973304_1	1521187.JPIM01000044_gene3305	1.456e-316	984.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi,375FT@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WLSH2_k127_8973304_15	304371.MCP_0932	3.999e-72	246.0	arCOG12320@1|root,arCOG12320@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8973304_17	118161.KB235922_gene1587	2.638e-61	217.0	arCOG13953@1|root,2ZC7Q@2|Bacteria,1G5IM@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8973304_14	446470.Snas_0871	5.594e-73	257.0	COG0793@1|root,COG0793@2|Bacteria,2GNJA@201174|Actinobacteria	201174|Actinobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
WLSH2_k127_8973304_21	452637.Oter_3829	3.253e-55	206.0	COG1524@1|root,COG1524@2|Bacteria,46VXF@74201|Verrucomicrobia,3K93S@414999|Opitutae	414999|Opitutae	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WLSH2_k127_8973304_26	374847.Kcr_0653	1.451e-45	172.0	COG0778@1|root,arCOG00288@2157|Archaea	2157|Archaea	C	Nitroreductase	-	-	1.5.1.39	ko:K19286	ko00740,ko01100,map00740,map01100	-	R05705,R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
WLSH2_k127_8973304_4	926569.ANT_28010	1.476e-223	701.0	COG1488@1|root,COG1488@2|Bacteria,2G73F@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	QRPTase_C,QRPTase_N
WLSH2_k127_8973304_6	211165.AJLN01000051_gene4893	8.05e-133	431.0	COG1335@1|root,COG1335@2|Bacteria,1G10P@1117|Cyanobacteria,1JHM2@1189|Stigonemataceae	1117|Cyanobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8973304_31	926569.ANT_14090	8.163e-32	131.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
WLSH2_k127_8973304_10	926569.ANT_14100	6.07e-102	346.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WLSH2_k127_8973304_9	926569.ANT_18600	3.756e-113	374.0	COG3191@1|root,COG3191@2|Bacteria,2G6BG@200795|Chloroflexi	200795|Chloroflexi	EQ	PFAM peptidase S58, DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
WLSH2_k127_8973304_33	926569.ANT_04160	3.076e-20	96.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
WLSH2_k127_8973304_22	926569.ANT_04150	1.143e-52	199.0	COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_8973304_18	926550.CLDAP_21910	8.7e-60	209.0	COG3631@1|root,COG3631@2|Bacteria,2G75M@200795|Chloroflexi	200795|Chloroflexi	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WLSH2_k127_8973304_27	32057.KB217478_gene3690	2.571e-40	153.0	COG0454@1|root,COG0456@2|Bacteria,1GDTV@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_8973304_0	926569.ANT_04140	0.0	1296.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WLSH2_k127_8973304_3	926569.ANT_29200	1.772e-227	723.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
WLSH2_k127_8973304_29	565033.GACE_0089	5.524e-36	140.0	COG1917@1|root,arCOG03004@2157|Archaea,2XYUR@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_8973304_13	324602.Caur_1591	4.786e-75	268.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ydeG	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_8973304_28	378806.STAUR_1465	7.471e-40	159.0	COG0454@1|root,COG0456@2|Bacteria,1R7PK@1224|Proteobacteria	1224|Proteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WLSH2_k127_8973304_16	515635.Dtur_1753	3.028e-63	248.0	COG1609@1|root,COG2199@1|root,COG2203@1|root,COG2206@1|root,COG1609@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	rpfG_3	-	-	ko:K02030,ko:K02103,ko:K02529	-	M00236	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1.3	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,Peripla_BP_3
WLSH2_k127_8973304_20	926569.ANT_15670	9.591e-57	227.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8973304_8	926569.ANT_25430	1.913e-113	376.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
WLSH2_k127_8973304_25	309807.SRU_0751	9.574e-51	189.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WLSH2_k127_8973304_11	1382356.JQMP01000003_gene1541	2.913e-101	338.0	COG1131@1|root,COG1131@2|Bacteria,2G7V6@200795|Chloroflexi,27Y6R@189775|Thermomicrobia	189775|Thermomicrobia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_8973304_30	1382356.JQMP01000003_gene1540	7.394e-36	138.0	COG0640@1|root,COG0640@2|Bacteria,2G9T1@200795|Chloroflexi,27ZA0@189775|Thermomicrobia	189775|Thermomicrobia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
WLSH2_k127_8973304_34	1382356.JQMP01000003_gene1539	3.071e-14	81.0	2A4V4@1|root,30TGQ@2|Bacteria,2GA4W@200795|Chloroflexi,27Z90@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8973304_7	926569.ANT_00050	3.241e-126	408.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_8991297_1	177437.HRM2_26180	2.647e-73	265.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
WLSH2_k127_8991297_3	394221.Mmar10_1682	1.709e-56	216.0	COG2730@1|root,COG2730@2|Bacteria,1PUWU@1224|Proteobacteria,2V6EP@28211|Alphaproteobacteria,43ZQQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8991297_2	1463855.JOHV01000010_gene5525	4.605e-57	211.0	COG0010@1|root,COG0010@2|Bacteria,2GJA6@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the arginase family	-	-	3.5.3.11,3.5.3.8	ko:K01479,ko:K01480	ko00330,ko00340,ko01100,map00330,map00340,map01100	M00045,M00133	R01157,R02285	RC00024,RC00221,RC00329,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WLSH2_k127_8991297_0	926550.CLDAP_27080	1.044e-80	273.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi	2|Bacteria	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	patA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K05830,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R01155,R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECIAI1_1343.ECIAI1_3220,iECSF_1327.ECSF_2916,iECs_1301.ECs3955,iZ_1308.Z4426	Aminotran_3
WLSH2_k127_8991421_1	1307436.PBF_18484	2.368e-10	73.0	COG3807@1|root,COG4990@1|root,COG3807@2|Bacteria,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HZA4@91061|Bacilli,1ZEKK@1386|Bacillus	91061|Bacilli	T	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,SH3_3,SLH
WLSH2_k127_8991421_0	935948.KE386495_gene1079	1.704e-109	363.0	COG2730@1|root,COG2730@2|Bacteria,1TQUA@1239|Firmicutes,248Y8@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	celC	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
WLSH2_k127_9100644_10	370438.PTH_2239	0.0009175	51.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,261RH@186807|Peptococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH2_k127_9100644_1	926569.ANT_23050	3.189e-110	366.0	COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Dehalogenase,Fer4_16,HEAT_2
WLSH2_k127_9100644_4	926569.ANT_04120	1.007e-65	230.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WLSH2_k127_9100644_6	357804.Ping_1892	5.34e-40	160.0	COG3675@1|root,COG3675@2|Bacteria,1ND8U@1224|Proteobacteria,1SCPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
WLSH2_k127_9100644_5	926569.ANT_13490	2.57e-46	181.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
WLSH2_k127_9100644_9	448385.sce5845	0.0003695	46.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
WLSH2_k127_9100644_8	483219.LILAB_15305	1.984e-06	53.0	29AZZ@1|root,30PVG@2|Bacteria,1Q1Z7@1224|Proteobacteria,434V6@68525|delta/epsilon subdivisions,2WZ6B@28221|Deltaproteobacteria,2Z1F3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9100644_2	1124780.ANNU01000058_gene886	1.117e-90	305.0	COG1024@1|root,COG1024@2|Bacteria,4NFEM@976|Bacteroidetes,47JUC@768503|Cytophagia	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH2_k127_9100644_3	926569.ANT_29760	9.513e-67	238.0	COG2746@1|root,COG2746@2|Bacteria	2|Bacteria	V	aminoglycoside 3-N-acetyltransferase activity	yokD	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
WLSH2_k127_9100644_7	751945.Theos_0886	9.399e-18	90.0	COG4113@1|root,COG4113@2|Bacteria,1WMZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_9100644_0	926569.ANT_01830	0.0	1339.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH2_k127_9113974_3	1245475.ANAE01000006_gene69	1.592e-27	128.0	COG2244@1|root,COG2244@2|Bacteria,2I4II@201174|Actinobacteria,4EGAH@85012|Streptosporangiales	201174|Actinobacteria	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt,Polysacc_synt_C
WLSH2_k127_9113974_5	1380370.JIBA01000016_gene670	2.074e-12	79.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2GJ1Y@201174|Actinobacteria,4FFZV@85021|Intrasporangiaceae	201174|Actinobacteria	DM	biosynthesis protein	wcoI	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
WLSH2_k127_9113974_2	309801.trd_A0816	2.113e-50	187.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WLSH2_k127_9113974_1	357808.RoseRS_1135	3.165e-99	333.0	COG0673@1|root,COG0673@2|Bacteria,2G6Y0@200795|Chloroflexi,376NR@32061|Chloroflexia	32061|Chloroflexia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_9113974_0	1094980.Mpsy_0708	9.372e-118	389.0	COG0399@1|root,arCOG00118@2157|Archaea,2XTRQ@28890|Euryarchaeota,2N9FX@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
WLSH2_k127_9113974_6	926569.ANT_19500	6.417e-12	70.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	rfaH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
WLSH2_k127_9113974_4	411477.PARMER_00996	1.158e-14	77.0	COG3666@1|root,COG3666@2|Bacteria,4NEDD@976|Bacteroidetes,2FNIQ@200643|Bacteroidia,22WUY@171551|Porphyromonadaceae	976|Bacteroidetes	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_9124325_1	211165.AJLN01000042_gene530	1.289e-130	423.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1JKQM@1189|Stigonemataceae	1117|Cyanobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
WLSH2_k127_9124325_5	796606.BMMGA3_04805	3.315e-09	59.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,1ZJQW@1386|Bacillus	91061|Bacilli	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_9124325_4	1536769.P40081_27435	1.163e-12	69.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,26U3R@186822|Paenibacillaceae	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WLSH2_k127_9124325_6	479431.Namu_4408	4.7e-05	50.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4EUIC@85013|Frankiales	201174|Actinobacteria	K	Response regulator receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_9124325_2	1128421.JAGA01000003_gene3537	6.972e-24	104.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_9124325_3	446468.Ndas_2859	1.426e-16	81.0	COG1226@1|root,32Y28@2|Bacteria	2|Bacteria	P	Ion transport 2 domain protein	RB9536	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
WLSH2_k127_9124325_0	1121403.AUCV01000010_gene1423	3.835e-135	441.0	COG5433@1|root,COG5433@2|Bacteria,1MXI8@1224|Proteobacteria,42WFU@68525|delta/epsilon subdivisions,2WS4T@28221|Deltaproteobacteria,2MKX1@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Pfam Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WLSH2_k127_913623_62	316274.Haur_2048	1.434e-27	114.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi,376XZ@32061|Chloroflexia	32061|Chloroflexia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
WLSH2_k127_913623_71	292564.Cyagr_2054	1.154e-10	64.0	COG4974@1|root,COG4974@2|Bacteria,1G2AH@1117|Cyanobacteria	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
WLSH2_k127_913623_70	913865.DOT_1769	8.372e-12	72.0	COG4974@1|root,COG4974@2|Bacteria,1U0MD@1239|Firmicutes,24FWH@186801|Clostridia,261AT@186807|Peptococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
WLSH2_k127_913623_15	329726.AM1_6258	1.824e-121	402.0	COG3464@1|root,COG3464@2|Bacteria,1G42D@1117|Cyanobacteria	1117|Cyanobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_913623_36	1089455.MOPEL_003_01150	1.523e-61	231.0	COG0437@1|root,COG0437@2|Bacteria,2HGMU@201174|Actinobacteria,4F7JN@85018|Dermatophilaceae	201174|Actinobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
WLSH2_k127_913623_4	484770.UFO1_2838	8.266e-246	782.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4H4MY@909932|Negativicutes	909932|Negativicutes	C	Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WLSH2_k127_913623_49	926569.ANT_24750	5.737e-48	177.0	COG2010@1|root,COG2010@2|Bacteria,2G7FH@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WLSH2_k127_913623_53	926569.ANT_24760	1.4e-35	141.0	2DSXF@1|root,33HTI@2|Bacteria,2G9HW@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
WLSH2_k127_913623_6	926569.ANT_24770	2.588e-200	633.0	COG5557@1|root,COG5557@2|Bacteria,2G68D@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
WLSH2_k127_913623_17	926569.ANT_24780	5.285e-109	359.0	COG0437@1|root,COG0437@2|Bacteria,2G6C1@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
WLSH2_k127_913623_5	926569.ANT_24790	3.902e-224	715.0	COG0243@1|root,COG0243@2|Bacteria,2G844@200795|Chloroflexi	200795|Chloroflexi	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
WLSH2_k127_913623_40	926569.ANT_24800	4.382e-58	207.0	COG3303@1|root,COG3303@2|Bacteria,2GBNG@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
WLSH2_k127_913623_19	1382306.JNIM01000001_gene3678	1.429e-94	324.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
WLSH2_k127_913623_41	260799.BAS0296	8.695e-58	206.0	COG1335@1|root,COG1335@2|Bacteria,1V7MY@1239|Firmicutes,4HDR2@91061|Bacilli,1ZD1Q@1386|Bacillus	91061|Bacilli	Q	Isochorismatase family	yddQ	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
WLSH2_k127_913623_30	761193.Runsl_4600	1.202e-68	238.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,4NI01@976|Bacteroidetes,47MZD@768503|Cytophagia	976|Bacteroidetes	L	Caulimovirus viroplasmin	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
WLSH2_k127_913623_73	1123373.ATXI01000003_gene1378	6.923e-10	70.0	COG3103@1|root,COG4991@2|Bacteria,2GHRI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_913623_50	926569.ANT_01990	3.229e-44	176.0	COG4447@1|root,COG4447@2|Bacteria,2G7EF@200795|Chloroflexi	200795|Chloroflexi	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_913623_7	926569.ANT_04950	5.513e-186	589.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_913623_64	926569.ANT_04490	1.626e-26	110.0	COG1146@1|root,COG1146@2|Bacteria,2G7ES@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
WLSH2_k127_913623_9	926569.ANT_04500	1.203e-175	557.0	COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH2_k127_913623_13	926569.ANT_04510	1.423e-131	423.0	COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi	200795|Chloroflexi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH2_k127_913623_27	926569.ANT_04520	1.496e-72	248.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1,1.2.7.3	ko:K00172,ko:K00177	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WLSH2_k127_913623_24	937777.Deipe_0686	1.765e-77	274.0	COG3178@1|root,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
WLSH2_k127_913623_45	63737.Npun_R5185	2.4e-50	196.0	COG3178@1|root,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
WLSH2_k127_913623_21	1170562.Cal6303_0644	1.54e-89	327.0	COG0443@1|root,COG0443@2|Bacteria,1G26I@1117|Cyanobacteria,1HIHB@1161|Nostocales	1117|Cyanobacteria	O	heat shock protein 70	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
WLSH2_k127_913623_79	1157490.EL26_02970	0.0009726	42.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli,27ANM@186823|Alicyclobacillaceae	91061|Bacilli	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	vicK	-	2.7.13.3	ko:K07652	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9
WLSH2_k127_913623_28	1231241.Mc24_02863	2.26e-72	252.0	COG0656@1|root,COG0656@2|Bacteria,2GCHS@200918|Thermotogae	200918|Thermotogae	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_913623_65	765420.OSCT_2130	1.051e-18	93.0	COG2127@1|root,COG2127@2|Bacteria,2G9F8@200795|Chloroflexi,375WT@32061|Chloroflexia	32061|Chloroflexia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
WLSH2_k127_913623_43	1123504.JQKD01000008_gene5341	4.162e-52	195.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WLSH2_k127_913623_54	926550.CLDAP_07570	1.389e-34	146.0	COG0392@1|root,COG0392@2|Bacteria,2G96G@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH2_k127_913623_18	706587.Desti_2994	8.782e-100	335.0	COG1063@1|root,COG1063@2|Bacteria,1MW7C@1224|Proteobacteria,430WX@68525|delta/epsilon subdivisions,2WW1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
WLSH2_k127_913623_46	926550.CLDAP_31610	1.938e-49	179.0	COG0720@1|root,COG0720@2|Bacteria,2G7B6@200795|Chloroflexi	200795|Chloroflexi	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WLSH2_k127_913623_20	706587.Desti_2992	4.099e-91	313.0	COG0438@1|root,COG0438@2|Bacteria,1P81Z@1224|Proteobacteria	1224|Proteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH2_k127_913623_29	706587.Desti_2991	2.987e-70	247.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,RrnaAD
WLSH2_k127_913623_34	395961.Cyan7425_4809	4.129e-63	227.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,3KGBC@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WLSH2_k127_913623_14	215803.DB30_2061	8.791e-131	429.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3335,Peptidase_C39,Peptidase_C39_2
WLSH2_k127_913623_11	765420.OSCT_2528	6.538e-143	466.0	COG0513@1|root,COG0513@2|Bacteria,2G5VR@200795|Chloroflexi,376J4@32061|Chloroflexia	200795|Chloroflexi	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WLSH2_k127_913623_47	102232.GLO73106DRAFT_00031350	9.045e-49	179.0	COG1848@1|root,COG1848@2|Bacteria,1G51H@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_913623_75	1123400.KB904803_gene1671	9.491e-09	58.0	2BGN2@1|root,32AKR@2|Bacteria,1NJT2@1224|Proteobacteria,1SVAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_913623_60	386456.JQKN01000006_gene1247	2.806e-29	121.0	arCOG11468@1|root,arCOG11468@2157|Archaea,2XZ82@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_913623_67	1220534.B655_2274	2.318e-15	80.0	arCOG11468@1|root,arCOG11468@2157|Archaea,2XZ82@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_913623_37	1123242.JH636434_gene3679	1.937e-61	213.0	COG0474@1|root,COG0474@2|Bacteria,2IYQI@203682|Planctomycetes	203682|Planctomycetes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH2_k127_913623_3	261292.Nit79A3_0034	2.197e-266	835.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,3743H@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH2_k127_913623_61	1384057.CD33_12725	9.943e-28	113.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,3IYM2@400634|Lysinibacillus	91061|Bacilli	K	Cold-shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WLSH2_k127_913623_68	864702.OsccyDRAFT_1813	6.227e-14	74.0	COG4113@1|root,COG4113@2|Bacteria,1G8IF@1117|Cyanobacteria,1HBD3@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_913623_78	864702.OsccyDRAFT_1813	0.0003245	43.0	COG4113@1|root,COG4113@2|Bacteria,1G8IF@1117|Cyanobacteria,1HBD3@1150|Oscillatoriales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_913623_31	1366050.N234_05385	4.894e-67	239.0	COG0697@1|root,COG0697@2|Bacteria,1NFUD@1224|Proteobacteria,2VPJH@28216|Betaproteobacteria,1K0I0@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_913623_77	215803.DB30_0713	4.319e-05	48.0	COG3350@1|root,COG3350@2|Bacteria,1QAHS@1224|Proteobacteria,4353K@68525|delta/epsilon subdivisions,2WZEJ@28221|Deltaproteobacteria,2Z1Z2@29|Myxococcales	28221|Deltaproteobacteria	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
WLSH2_k127_913623_55	28072.Nos7524_2815	3.122e-34	137.0	2C7RX@1|root,32RJP@2|Bacteria,1G859@1117|Cyanobacteria,1HSHI@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_913623_59	56110.Oscil6304_1813	1.186e-30	124.0	2C4F2@1|root,331RG@2|Bacteria,1G9S1@1117|Cyanobacteria,1HDB3@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_913623_10	926569.ANT_08530	1.27e-144	464.0	COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi	200795|Chloroflexi	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WLSH2_k127_913623_38	926569.ANT_08510	4.235e-61	216.0	COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
WLSH2_k127_913623_22	747365.Thena_1678	5.375e-87	295.0	COG0623@1|root,COG0623@2|Bacteria,1TPVD@1239|Firmicutes,24EJB@186801|Clostridia,42I6Q@68295|Thermoanaerobacterales	186801|Clostridia	I	Short-chain dehydrogenase reductase SDR	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_913623_48	926569.ANT_08490	1.257e-48	179.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WLSH2_k127_913623_32	243164.DET0368	1.467e-66	241.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi,34CJ8@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
WLSH2_k127_913623_23	926569.ANT_08430	2.344e-84	287.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi	200795|Chloroflexi	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
WLSH2_k127_913623_35	1049564.TevJSym_ae00690	4.519e-63	224.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,1S3UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
WLSH2_k127_913623_25	1230476.C207_02861	3.136e-76	259.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,3JQN6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1,4.6.1.2	ko:K01768,ko:K01769	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,Guanylate_cyc,HAMP
WLSH2_k127_913623_57	357808.RoseRS_1536	3.297e-32	139.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
WLSH2_k127_913623_58	867845.KI911784_gene2572	4.925e-31	134.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
WLSH2_k127_913623_56	1385510.N781_01925	1.788e-32	132.0	COG1051@1|root,COG1051@2|Bacteria,1VA5T@1239|Firmicutes,4IKH8@91061|Bacilli,2YBR1@289201|Pontibacillus	91061|Bacilli	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_913623_51	762903.Pedsa_0003	1.075e-41	159.0	COG0494@1|root,COG0494@2|Bacteria,4NNGW@976|Bacteroidetes,1IS81@117747|Sphingobacteriia	976|Bacteroidetes	L	pfam nudix	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_913623_16	383372.Rcas_3780	6.813e-117	383.0	COG0208@1|root,COG0208@2|Bacteria,2G610@200795|Chloroflexi,3761D@32061|Chloroflexia	32061|Chloroflexia	F	PFAM ribonucleotide reductase	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
WLSH2_k127_913623_52	1312959.KI914701_gene2868	4.954e-41	158.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria,1W8YK@1268|Micrococcaceae	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
WLSH2_k127_913623_39	102129.Lepto7375DRAFT_7605	3.183e-59	213.0	COG2890@1|root,COG2890@2|Bacteria,1G69N@1117|Cyanobacteria,1HGY2@1150|Oscillatoriales	1117|Cyanobacteria	J	RNA cap guanine-N2 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH2_k127_913623_2	926569.ANT_30270	2.353e-267	841.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,2G75J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_913623_0	326427.Cagg_1166	4.59e-305	945.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi,376PZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_913623_63	326427.Cagg_1165	1.321e-26	111.0	COG1977@1|root,COG1977@2|Bacteria,2G9DU@200795|Chloroflexi,377DC@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH2_k127_913623_74	326427.Cagg_1165	5.22e-09	61.0	COG1977@1|root,COG1977@2|Bacteria,2G9DU@200795|Chloroflexi,377DC@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM MoaD family protein	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH2_k127_913623_8	926550.CLDAP_40590	8.198e-181	574.0	COG0535@1|root,COG2002@1|root,COG0535@2|Bacteria,COG2002@2|Bacteria,2G75Y@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
WLSH2_k127_913623_12	926569.ANT_29410	2.553e-137	446.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WLSH2_k127_913623_66	243090.RB5670	1.933e-16	85.0	COG0607@1|root,COG0607@2|Bacteria,2J06B@203682|Planctomycetes	203682|Planctomycetes	P	COG0607 Rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_913623_1	926569.ANT_05040	2.035e-291	914.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
WLSH2_k127_913623_26	525897.Dbac_1216	1.253e-75	260.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PNX@68525|delta/epsilon subdivisions,2WK8F@28221|Deltaproteobacteria,2M8X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
WLSH2_k127_913623_33	926560.KE387023_gene2224	4.086e-64	228.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	eryCVI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983	2.1.1.234	ko:K13311,ko:K13326,ko:K21335	ko00523,ko01130,map00523,map01130	M00797,M00800	R06427,R11045,R11476	RC00003,RC01515,RC02262	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
WLSH2_k127_9152930_1	926569.ANT_26640	4.532e-31	132.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WLSH2_k127_9152930_0	479434.Sthe_2851	1.856e-45	175.0	COG1402@1|root,COG1402@2|Bacteria,2G7B0@200795|Chloroflexi	200795|Chloroflexi	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WLSH2_k127_9152930_2	1340493.JNIF01000004_gene718	7.726e-14	85.0	COG2234@1|root,COG2234@2|Bacteria,3Y33F@57723|Acidobacteria	57723|Acidobacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
WLSH2_k127_915495_2	338966.Ppro_0800	0.0002575	49.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WLSH2_k127_915495_0	179408.Osc7112_0570	1.647e-46	169.0	COG4634@1|root,COG4634@2|Bacteria,1G8GS@1117|Cyanobacteria,1HCSC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_915495_1	272134.KB731324_gene6103	4.23e-32	126.0	COG2442@1|root,COG2442@2|Bacteria,1G869@1117|Cyanobacteria,1HCJ2@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
WLSH2_k127_9160542_0	926569.ANT_08340	9.551e-201	635.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WLSH2_k127_9160542_2	926569.ANT_08330	3.833e-62	217.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WLSH2_k127_9160542_1	926569.ANT_08320	2.746e-192	607.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
WLSH2_k127_9175306_4	1521187.JPIM01000005_gene2268	6.146e-15	78.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG1609@1|root,COG2207@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1609@2|Bacteria,COG2205@2|Bacteria,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K02529,ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,Cupin_2,HATPase_c,HTH_18,HisKA,Peripla_BP_3,Response_reg
WLSH2_k127_9175306_5	926569.ANT_30020	3.759e-14	74.0	COG1662@1|root,COG1662@2|Bacteria	2|Bacteria	L	PFAM IS1 transposase	-	-	-	ko:K07480	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1
WLSH2_k127_9175306_1	926569.ANT_27860	2.303e-42	168.0	COG3595@1|root,COG3595@2|Bacteria,2G73J@200795|Chloroflexi	200795|Chloroflexi	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
WLSH2_k127_9175306_3	926560.KE387023_gene1958	2.706e-27	119.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9175306_0	926569.ANT_09240	4.195e-122	406.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM	-	-	-	-	-	-	-	-	-	-	-	MatE
WLSH2_k127_9175306_2	926569.ANT_14540	1.044e-27	123.0	COG0115@1|root,COG0115@2|Bacteria,2G8EE@200795|Chloroflexi	200795|Chloroflexi	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WLSH2_k127_9175306_6	926550.CLDAP_24870	3.579e-11	66.0	COG1132@1|root,COG1132@2|Bacteria,2G7KM@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_924566_1	696747.NIES39_O06490	3.759e-56	203.0	COG0726@1|root,COG0726@2|Bacteria,1G02J@1117|Cyanobacteria,1H87V@1150|Oscillatoriales	1117|Cyanobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WLSH2_k127_924566_3	485913.Krac_7590	8.735e-28	124.0	COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_924566_7	46234.ANA_C10184	8.23e-12	67.0	2DRFW@1|root,33BJE@2|Bacteria,1GEZ6@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_924566_5	118168.MC7420_4040	6.417e-17	81.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_924566_6	113355.CM001775_gene344	8.889e-14	72.0	COG1487@1|root,COG1487@2|Bacteria,1G98C@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WLSH2_k127_924566_0	1499967.BAYZ01000033_gene1106	1.64e-77	265.0	COG3382@1|root,COG3382@2|Bacteria	2|Bacteria	J	B3 4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
WLSH2_k127_924566_4	391612.CY0110_27475	2.397e-23	102.0	2C6B2@1|root,3318T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_924566_2	671143.DAMO_2394	1.616e-34	134.0	COG2929@1|root,COG2929@2|Bacteria,2NRJD@2323|unclassified Bacteria	2|Bacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
WLSH2_k127_924566_8	485913.Krac_2962	1.061e-09	64.0	COG2801@1|root,COG2801@2|Bacteria,2G9MD@200795|Chloroflexi	200795|Chloroflexi	L	SPTR A9B8L4 Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
WLSH2_k127_9264653_10	525904.Tter_2548	9.612e-28	115.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,HATPase_c,HisKA_3,Response_reg
WLSH2_k127_9264653_8	1123288.SOV_2c03000	1.23e-62	236.0	COG2202@1|root,COG3850@1|root,COG2202@2|Bacteria,COG3850@2|Bacteria,1UNYH@1239|Firmicutes,4H8IN@909932|Negativicutes	2|Bacteria	T	N-terminal 7TM region of histidine kinase	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3,HisKA_7TM,MFS_1,PAS,PAS_3,PAS_9,PilJ
WLSH2_k127_9264653_3	316274.Haur_4334	9.203e-168	551.0	COG1501@1|root,COG1501@2|Bacteria,2G5TX@200795|Chloroflexi,376YU@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_31
WLSH2_k127_9264653_0	1499967.BAYZ01000104_gene3639	1.707e-266	828.0	2BZA3@1|root,2Z7YV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9264653_6	324602.Caur_2676	1.286e-90	306.0	COG0395@1|root,COG0395@2|Bacteria,2G6JM@200795|Chloroflexi,37760@32061|Chloroflexia	32061|Chloroflexia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH2_k127_9264653_7	697281.Mahau_0769	8.749e-65	235.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42FXR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH2_k127_9264653_4	324602.Caur_2674	2.281e-123	408.0	COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi,377G1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
WLSH2_k127_9264653_5	926569.ANT_04610	3.789e-102	342.0	COG1609@1|root,COG1609@2|Bacteria,2G855@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WLSH2_k127_9264653_13	1229487.AMYW01000015_gene2395	2.027e-09	61.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,1HYQP@117743|Flavobacteriia,2NU9S@237|Flavobacterium	976|Bacteroidetes	G	Catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
WLSH2_k127_9264653_11	402777.KB235903_gene1475	3.213e-24	109.0	28JE3@1|root,2Z98B@2|Bacteria,1G13G@1117|Cyanobacteria,1H9TN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9264653_12	1121918.ARWE01000001_gene1726	6.109e-21	94.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42WQS@68525|delta/epsilon subdivisions,2WRPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WLSH2_k127_9264653_2	765420.OSCT_2228	3.158e-170	567.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160,YARHG,zinc_ribbon_2
WLSH2_k127_9264653_9	765420.OSCT_0886	2.078e-43	164.0	COG0577@1|root,COG0577@2|Bacteria,2G6MK@200795|Chloroflexi,376DE@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_9271693_7	1536775.H70737_05250	1.902e-14	81.0	2DBAX@1|root,2Z84Q@2|Bacteria,1VHQG@1239|Firmicutes,4HPN3@91061|Bacilli,26X2H@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
WLSH2_k127_9271693_8	1173027.Mic7113_5944	6.311e-13	71.0	COG0675@1|root,COG0675@2|Bacteria,1G01E@1117|Cyanobacteria,1H7AA@1150|Oscillatoriales	1117|Cyanobacteria	L	COG0675 Transposase and inactivated derivatives	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
WLSH2_k127_9271693_0	485913.Krac_3483	8.546e-136	445.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WLSH2_k127_9271693_5	744872.Spica_1005	7.102e-51	190.0	2C73B@1|root,330Z7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
WLSH2_k127_9271693_4	926569.ANT_18550	1.266e-60	220.0	COG1752@1|root,COG1752@2|Bacteria,2G70S@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WLSH2_k127_9271693_6	926569.ANT_18570	3.088e-30	129.0	COG0400@1|root,COG0400@2|Bacteria,2G7EK@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
WLSH2_k127_9271693_1	926569.ANT_18500	3.264e-102	345.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
WLSH2_k127_9271693_2	926569.ANT_18490	4.418e-95	316.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WLSH2_k127_9271693_3	926569.ANT_18470	2.421e-75	264.0	COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WLSH2_k127_9290126_3	283942.IL1280	3.399e-56	202.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,2QFS5@267893|Idiomarinaceae	1236|Gammaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974	DHO_dh
WLSH2_k127_9290126_2	357808.RoseRS_2229	1.994e-82	300.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WLSH2_k127_9290126_0	926569.ANT_06270	3.171e-222	696.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WLSH2_k127_9290126_4	1144343.PMI41_01249	1.204e-41	156.0	COG0346@1|root,COG0346@2|Bacteria,1N15G@1224|Proteobacteria,2UCYE@28211|Alphaproteobacteria,43KUM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WLSH2_k127_9290126_7	266265.Bxe_B0639	3.017e-05	46.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6V4@1224|Proteobacteria,2VMXP@28216|Betaproteobacteria,1K10W@119060|Burkholderiaceae	28216|Betaproteobacteria	P	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
WLSH2_k127_9290126_6	926569.ANT_16540	4.645e-11	68.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_9290126_1	1444309.JAQG01000106_gene1146	2.522e-86	292.0	COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,26S9J@186822|Paenibacillaceae	91061|Bacilli	E	oligoendopeptidase F	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH2_k127_9290409_2	316274.Haur_3999	3.701e-157	505.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi,374ZR@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_9290409_6	357808.RoseRS_4156	6.579e-110	363.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi,375B0@32061|Chloroflexia	32061|Chloroflexia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_9290409_5	765420.OSCT_1170	6.725e-117	386.0	COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like,PBP_like_2
WLSH2_k127_9290409_18	926569.ANT_08200	1.848e-52	190.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WLSH2_k127_9290409_20	926569.ANT_23540	1.971e-49	184.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
WLSH2_k127_9290409_22	857087.Metme_0945	4.814e-41	162.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	sixA-2	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,His_Phos_1
WLSH2_k127_9290409_25	1340493.JNIF01000003_gene3925	4.886e-28	120.0	COG2062@1|root,COG2062@2|Bacteria,3Y5YQ@57723|Acidobacteria	57723|Acidobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WLSH2_k127_9290409_0	1303518.CCALI_00492	1.33e-210	677.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WLSH2_k127_9290409_4	926569.ANT_01750	5.66e-119	394.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
WLSH2_k127_9290409_10	926569.ANT_01760	7.319e-96	318.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_9290409_30	1243664.CAVL020000054_gene3105	9.5e-20	93.0	COG0607@1|root,COG0607@2|Bacteria,1VES3@1239|Firmicutes,4HNRE@91061|Bacilli,1ZI0X@1386|Bacillus	91061|Bacilli	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_9290409_3	765420.OSCT_2914	2.055e-119	401.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	pds	-	1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6	ko:K00231,ko:K00514,ko:K02293,ko:K09879,ko:K21677	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	M00097,M00121	R03222,R04178,R04786,R04787,R04798,R04800,R07510,R07511,R07541,R07560,R07857,R07858,R09652,R09653,R09654,R09656,R09658	RC00885,RC01214,RC01901,RC01958,RC01959,RC01965,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
WLSH2_k127_9290409_32	176946.XP_007436286.1	3.887e-08	65.0	COG2896@1|root,KOG2876@2759|Eukaryota,38F0A@33154|Opisthokonta,3B9J0@33208|Metazoa,3D129@33213|Bilateria,4862I@7711|Chordata,48Y19@7742|Vertebrata	33208|Metazoa	H	GTP 3',8'-cyclase activity	MOCS1	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016829,GO:0016830,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051189,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0061798,GO:0061799,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	4.1.99.22,4.6.1.17	ko:K20967	ko00790,ko01100,map00790,map01100	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,MoaC,Mob_synth_C,Radical_SAM
WLSH2_k127_9290409_7	742817.HMPREF9449_02255	4.208e-108	369.0	COG0490@1|root,COG2985@1|root,COG0490@2|Bacteria,COG2985@2|Bacteria,4NEBW@976|Bacteroidetes,2FMDF@200643|Bacteroidia,22XD6@171551|Porphyromonadaceae	976|Bacteroidetes	P	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
WLSH2_k127_9290409_8	1123508.JH636443_gene4982	6.6e-108	355.0	COG0491@1|root,COG0491@2|Bacteria,2IXNH@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9290409_29	472759.Nhal_0278	3.409e-22	98.0	2EBQI@1|root,335QJ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
WLSH2_k127_9290409_26	641143.HMPREF9331_00307	9.088e-28	114.0	arCOG08856@1|root,30KI3@2|Bacteria,4NY5J@976|Bacteroidetes,1IEY6@117743|Flavobacteriia,1ERQX@1016|Capnocytophaga	976|Bacteroidetes	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9290409_31	671143.DAMO_0971	1.278e-13	72.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
WLSH2_k127_9290409_24	270374.MELB17_22630	6.096e-34	132.0	2C1FP@1|root,32YNH@2|Bacteria,1NB4D@1224|Proteobacteria,1SECT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9290409_21	1499967.BAYZ01000089_gene5006	5.83e-46	168.0	COG4226@1|root,COG4226@2|Bacteria,2NPM1@2323|unclassified Bacteria	2|Bacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
WLSH2_k127_9290409_1	926569.ANT_00490	1.205e-205	654.0	COG0433@1|root,COG0433@2|Bacteria,2G62A@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
WLSH2_k127_9290409_17	1033743.CAES01000062_gene9	1.188e-60	218.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,4HB4C@91061|Bacilli,2777Z@186822|Paenibacillaceae	91061|Bacilli	E	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
WLSH2_k127_9290409_13	926569.ANT_30470	1.426e-75	268.0	COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi	200795|Chloroflexi	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
WLSH2_k127_9290409_19	926569.ANT_30480	3.862e-52	193.0	COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
WLSH2_k127_9290409_12	864702.OsccyDRAFT_4839	1.755e-90	307.0	COG2084@1|root,COG2084@2|Bacteria,1G1GH@1117|Cyanobacteria,1HEPB@1150|Oscillatoriales	1117|Cyanobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WLSH2_k127_9290409_9	926569.ANT_02930	3.25e-105	349.0	COG1284@1|root,COG1284@2|Bacteria,2G6SY@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WLSH2_k127_9290409_28	926569.ANT_01470	7.456e-25	112.0	COG3714@1|root,COG3714@2|Bacteria	2|Bacteria	S	YhhN family	yhhN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	YhhN
WLSH2_k127_9290409_11	926569.ANT_01460	7.546e-96	323.0	COG1159@1|root,COG1159@2|Bacteria,2G69C@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WLSH2_k127_9290409_33	512565.AMIS_66540	1.546e-07	64.0	COG1807@1|root,COG1807@2|Bacteria,2GK3Q@201174|Actinobacteria,4D9YJ@85008|Micromonosporales	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH2_k127_9290409_23	743721.Psesu_1933	2.749e-35	141.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1X6DF@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
WLSH2_k127_9290409_16	926569.ANT_00660	4.489e-61	223.0	COG0287@1|root,COG0287@2|Bacteria,2G9BH@200795|Chloroflexi	200795|Chloroflexi	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
WLSH2_k127_9290409_27	926569.ANT_00650	1.377e-26	111.0	COG2827@1|root,COG2827@2|Bacteria,2G9H6@200795|Chloroflexi	200795|Chloroflexi	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH2_k127_9290409_14	926569.ANT_00640	1.865e-63	219.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WLSH2_k127_9295040_8	309799.DICTH_0557	5.661e-51	186.0	COG1104@1|root,COG1104@2|Bacteria	2|Bacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WLSH2_k127_9295040_5	1128421.JAGA01000003_gene3306	7.022e-68	243.0	COG2390@1|root,COG2390@2|Bacteria,2NQXC@2323|unclassified Bacteria	2|Bacteria	K	Putative sugar-binding domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_28,Sigma70_r4,Sugar-bind
WLSH2_k127_9295040_3	1128421.JAGA01000003_gene3315	4.1e-111	368.0	COG1071@1|root,COG1071@2|Bacteria,2NQNM@2323|unclassified Bacteria	2|Bacteria	C	Dehydrogenase E1 component	acoA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WLSH2_k127_9295040_2	1122947.FR7_1921	8.074e-131	424.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4H3G6@909932|Negativicutes	1239|Firmicutes	C	Transketolase, pyrimidine binding domain	acoB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WLSH2_k127_9295040_4	1122919.KB905586_gene3795	1.637e-81	289.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli,26R2C@186822|Paenibacillaceae	91061|Bacilli	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	acoC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WLSH2_k127_9295040_9	221288.JH992901_gene2716	9.256e-23	100.0	COG1080@1|root,COG1080@2|Bacteria,1G0VI@1117|Cyanobacteria,1JHDA@1189|Stigonemataceae	1117|Cyanobacteria	G	PTS HPr component phosphorylation site	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_1,PTS_EIIA_2
WLSH2_k127_9295040_1	1089548.KI783301_gene617	8.442e-149	490.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli,3WE7R@539002|Bacillales incertae sedis	91061|Bacilli	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
WLSH2_k127_9295040_7	203124.Tery_0519	2.274e-62	221.0	COG0176@1|root,COG0176@2|Bacteria,1G20F@1117|Cyanobacteria,1H7FB@1150|Oscillatoriales	1117|Cyanobacteria	H	Transaldolase	talC	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
WLSH2_k127_9295040_6	515635.Dtur_0729	2.058e-65	229.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,URO-D
WLSH2_k127_9295040_0	1116369.KB890024_gene3583	3.709e-165	531.0	COG3775@1|root,COG3775@2|Bacteria,1MVRC@1224|Proteobacteria,2TXEI@28211|Alphaproteobacteria,43I4M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	system Galactitol-specific IIC component	-	-	-	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	M00279	R05570	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.5.1	-	-	EIIC-GAT
WLSH2_k127_9315075_1	697282.Mettu_2324	2.434e-27	130.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,1S0DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
WLSH2_k127_9315075_0	1501230.ET33_02970	7.918e-134	462.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
WLSH2_k127_9415649_2	926550.CLDAP_01170	1.466e-69	255.0	COG0747@1|root,COG0747@2|Bacteria,2G6MN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_9415649_0	324602.Caur_2783	2.4e-99	335.0	COG0601@1|root,COG0601@2|Bacteria,2G662@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_9415649_1	324602.Caur_2782	2.896e-91	309.0	COG1173@1|root,COG1173@2|Bacteria,2G853@200795|Chloroflexi	200795|Chloroflexi	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WLSH2_k127_9415649_3	1304874.JAFY01000002_gene574	3.886e-61	230.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
WLSH2_k127_9415649_4	1304874.JAFY01000002_gene574	4.974e-47	183.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
WLSH2_k127_9453363_2	517417.Cpar_1669	1.729e-39	150.0	COG1294@1|root,COG1294@2|Bacteria,1FDE9@1090|Chlorobi	1090|Chlorobi	C	Cytochrome d ubiquinol oxidase, subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
WLSH2_k127_9453363_0	765420.OSCT_1692	1.382e-250	816.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2G7JB@200795|Chloroflexi	200795|Chloroflexi	CO	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
WLSH2_k127_9453363_3	1463820.JOGW01000014_gene632	0.0004153	49.0	COG3427@1|root,COG3427@2|Bacteria,2IJAS@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WLSH2_k127_9453363_1	926569.ANT_09360	5.932e-199	628.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WLSH2_k127_9479633_13	572547.Amico_0686	8.578e-13	75.0	COG1030@1|root,COG1030@2|Bacteria,3TAG8@508458|Synergistetes	508458|Synergistetes	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
WLSH2_k127_9479633_2	926569.ANT_29010	8.664e-142	454.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH2_k127_9479633_11	926569.ANT_29020	1.799e-29	123.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WLSH2_k127_9479633_5	926569.ANT_02860	1.176e-86	299.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WLSH2_k127_9479633_0	926569.ANT_02850	8.914e-201	634.0	COG1236@1|root,COG1236@2|Bacteria,2G62G@200795|Chloroflexi	200795|Chloroflexi	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
WLSH2_k127_9479633_8	714943.Mucpa_3589	3.663e-60	224.0	COG1835@1|root,COG1835@2|Bacteria,4NIVR@976|Bacteroidetes,1ITNG@117747|Sphingobacteriia	976|Bacteroidetes	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WLSH2_k127_9479633_7	1262449.CP6013_0475	2.404e-70	252.0	COG1835@1|root,COG1835@2|Bacteria,1V7CG@1239|Firmicutes,24WKR@186801|Clostridia	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WLSH2_k127_9479633_9	382464.ABSI01000010_gene3363	2.199e-59	221.0	COG4585@1|root,COG4585@2|Bacteria,46SBM@74201|Verrucomicrobia,2IV76@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_4
WLSH2_k127_9479633_6	1089545.KB913037_gene479	1.273e-77	265.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DYVZ@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_9479633_1	42256.RradSPS_0358	4.781e-188	618.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
WLSH2_k127_9479633_10	1042877.GQS_02930	1.426e-56	207.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota	28890|Euryarchaeota	S	metal-dependent membrane protease	-	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0071944,GO:0080120,GO:0140096,GO:1901564	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_9479633_4	1089553.Tph_c21880	1.94e-90	319.0	COG0815@1|root,COG0815@2|Bacteria,1V095@1239|Firmicutes,24B2E@186801|Clostridia	186801|Clostridia	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WLSH2_k127_9479633_12	1273538.G159_04940	3.311e-17	83.0	2DNVA@1|root,32ZBE@2|Bacteria,1W480@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9479633_3	189425.PGRAT_19655	1.532e-93	314.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
WLSH2_k127_9509822_1	926569.ANT_03810	4.07e-86	300.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
WLSH2_k127_9509822_2	1469607.KK073768_gene3614	1.631e-79	273.0	COG3293@1|root,COG3293@2|Bacteria,1G0BW@1117|Cyanobacteria,1HNSC@1161|Nostocales	1117|Cyanobacteria	L	transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
WLSH2_k127_9509822_5	385682.AFSL01000063_gene1519	1.731e-36	158.0	COG3023@1|root,COG3103@1|root,COG3023@2|Bacteria,COG3103@2|Bacteria,4NE38@976|Bacteroidetes,2FVEF@200643|Bacteroidia,3XKNZ@558415|Marinilabiliaceae	976|Bacteroidetes	TV	Ami_2	-	-	3.5.1.28	ko:K11066	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2,SH3_3
WLSH2_k127_9509822_4	926569.ANT_03610	2.018e-65	234.0	COG1708@1|root,COG1708@2|Bacteria,2G7IZ@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4111)	-	-	2.7.7.47	ko:K00984	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2
WLSH2_k127_9509822_0	479434.Sthe_1490	2.088e-144	475.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH2_k127_9509822_7	1120950.KB892817_gene7191	1.163e-12	68.0	COG0454@1|root,COG0456@2|Bacteria,2IIN6@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_9509822_8	103690.17132225	2.794e-08	56.0	COG0454@1|root,COG0456@2|Bacteria,1G5GC@1117|Cyanobacteria	1117|Cyanobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
WLSH2_k127_9509822_9	1120950.KB892817_gene7191	9.243e-05	46.0	COG0454@1|root,COG0456@2|Bacteria,2IIN6@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH2_k127_9509822_6	204773.HEAR2140	1.933e-21	98.0	COG1359@1|root,COG1359@2|Bacteria,1NG3M@1224|Proteobacteria,2W4IR@28216|Betaproteobacteria,477TI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WLSH2_k127_9509822_3	886377.Murru_1453	1.071e-73	256.0	COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes,1HXI5@117743|Flavobacteriia	976|Bacteroidetes	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
WLSH2_k127_951673_39	485913.Krac_2177	2.301e-05	49.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH2_k127_951673_13	1265505.ATUG01000002_gene1171	2.914e-128	446.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,434EE@68525|delta/epsilon subdivisions,2WYRT@28221|Deltaproteobacteria,2MN3I@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
WLSH2_k127_951673_30	522306.CAP2UW1_3042	5.091e-35	156.0	COG1639@1|root,COG2114@1|root,COG1639@2|Bacteria,COG2114@2|Bacteria,1RASR@1224|Proteobacteria,2VR0D@28216|Betaproteobacteria	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
WLSH2_k127_951673_14	1499967.BAYZ01000171_gene5534	5.024e-123	413.0	COG0589@1|root,COG1475@1|root,COG0589@2|Bacteria,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc,Usp
WLSH2_k127_951673_7	497964.CfE428DRAFT_0631	1.332e-186	619.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
WLSH2_k127_951673_5	497964.CfE428DRAFT_0631	8.793e-198	652.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
WLSH2_k127_951673_10	1242864.D187_000948	3.272e-168	559.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,Peptidase_M1
WLSH2_k127_951673_33	1173024.KI912148_gene3044	1.089e-29	128.0	COG0454@1|root,COG0456@2|Bacteria,1GGD2@1117|Cyanobacteria	1117|Cyanobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_951673_28	926569.ANT_29860	5.704e-42	159.0	2A540@1|root,30TSN@2|Bacteria,2G9TT@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_951673_18	926569.ANT_29850	4.046e-93	329.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_951673_20	479434.Sthe_1367	9.157e-76	265.0	COG2378@1|root,COG2378@2|Bacteria,2G8BW@200795|Chloroflexi	200795|Chloroflexi	K	Helix-turn-helix type 11 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
WLSH2_k127_951673_34	1121335.Clst_0570	3.636e-29	122.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1TQKE@1239|Firmicutes,24JKZ@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18
WLSH2_k127_951673_6	926569.ANT_06480	1.046e-186	599.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_951673_38	926569.ANT_04790	2.851e-14	88.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	3.5.1.104	ko:K07273,ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_25,LysM
WLSH2_k127_951673_19	349124.Hhal_1076	3.585e-90	334.0	COG1173@1|root,COG1173@2|Bacteria,1R4K8@1224|Proteobacteria,1SYV4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EP	Pfam Binding-protein-dependent transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_951673_23	1121939.L861_22660	5.769e-60	238.0	COG0601@1|root,COG0601@2|Bacteria,1R3Q1@1224|Proteobacteria,1SKHM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_951673_31	272558.10176004	1.025e-34	144.0	COG0457@1|root,COG0457@2|Bacteria,1U9ZE@1239|Firmicutes,4IK7A@91061|Bacilli,1ZFKG@1386|Bacillus	91061|Bacilli	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
WLSH2_k127_951673_12	926569.ANT_06470	1.773e-135	436.0	COG2089@1|root,COG2089@2|Bacteria,2G8IV@200795|Chloroflexi	200795|Chloroflexi	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
WLSH2_k127_951673_11	926569.ANT_06460	9.744e-163	521.0	COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria	2|Bacteria	S	3-deoxy-manno-octulosonate-8-phosphatase activity	neuA	-	2.7.7.43,3.1.3.45	ko:K00983,ko:K03270	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
WLSH2_k127_951673_16	926569.ANT_06450	1.597e-110	364.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WLSH2_k127_951673_36	1123008.KB905700_gene2079	1.747e-17	96.0	28PN7@1|root,2ZCB2@2|Bacteria,4NJSS@976|Bacteroidetes,2FTMW@200643|Bacteroidia,22Y3X@171551|Porphyromonadaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_951673_1	867845.KI911784_gene1213	1.236e-271	845.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi,376A2@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
WLSH2_k127_951673_37	515635.Dtur_1406	2.57e-16	91.0	COG1284@1|root,COG1284@2|Bacteria	2|Bacteria	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	yvjA	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WLSH2_k127_951673_24	1128421.JAGA01000003_gene3171	2.448e-57	213.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
WLSH2_k127_951673_4	1131462.DCF50_p1622	3.06e-208	673.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,260KC@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM formate dehydrogenase, alpha subunit	nuoG	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WLSH2_k127_951673_2	926569.ANT_17820	2.513e-252	788.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	-	-	1.6.5.3	ko:K00335,ko:K05587	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
WLSH2_k127_951673_26	926569.ANT_17810	1.171e-52	190.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	nuoE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WLSH2_k127_951673_32	926569.ANT_17790	2.556e-31	126.0	COG3411@1|root,COG3411@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K17992	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
WLSH2_k127_951673_27	1089553.Tph_c26370	1.189e-45	171.0	COG0680@1|root,COG0680@2|Bacteria,1V5D9@1239|Firmicutes,24IZJ@186801|Clostridia,42GH1@68295|Thermoanaerobacterales	186801|Clostridia	C	Hydrogenase maturation protease	-	-	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WLSH2_k127_951673_29	1111728.ATYS01000041_gene2560	4.262e-39	149.0	2DM97@1|root,327XJ@2|Bacteria,1QUUV@1224|Proteobacteria,1T21T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	formate hydrogenlyase maturation	hyfJ	-	-	ko:K12145,ko:K15834	-	-	-	-	ko00000,ko01000	-	-	-	HycH
WLSH2_k127_951673_17	104623.Ser39006_02027	2.592e-109	359.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,1RNUG@1236|Gammaproteobacteria,3ZZN2@613|Serratia	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hyfI	GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	-	ko:K12144,ko:K14088,ko:K15832	-	-	-	-	ko00000,ko01000	-	-	iECSP_1301.ECSP_3428,iECs_1301.ECs3351	Oxidored_q6
WLSH2_k127_951673_22	104623.Ser39006_02028	1.399e-62	220.0	COG1143@1|root,COG1143@2|Bacteria,1R9YT@1224|Proteobacteria,1RQB1@1236|Gammaproteobacteria,401YZ@613|Serratia	1236|Gammaproteobacteria	C	the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3	hyfH	-	-	ko:K12143,ko:K15831	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_7
WLSH2_k127_951673_0	264732.Moth_2186	4.323e-284	882.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1VZGX@1239|Firmicutes,248UJ@186801|Clostridia,42EKZ@68295|Thermoanaerobacterales	186801|Clostridia	C	Nickel-dependent hydrogenase	-	-	-	ko:K15830	-	-	-	-	ko00000	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
WLSH2_k127_951673_8	1123487.KB892864_gene2148	6.667e-184	588.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria,2KVZF@206389|Rhodocyclales	206389|Rhodocyclales	CP	Proton-conducting membrane transporter	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
WLSH2_k127_951673_21	1121033.AUCF01000034_gene3561	1.045e-70	245.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2UHD9@28211|Alphaproteobacteria,2JXQX@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q2
WLSH2_k127_951673_9	264732.Moth_2187	3.384e-180	576.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,24A16@186801|Clostridia,42FX8@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	-	ko:K12139	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WLSH2_k127_951673_15	273068.TTE1705	2.231e-114	376.0	COG0650@1|root,COG0650@2|Bacteria,1UERZ@1239|Firmicutes,24ARH@186801|Clostridia,42FZ3@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH dehydrogenase	-	-	-	ko:K12138	-	-	-	-	ko00000,ko01000	-	-	-	NADHdh
WLSH2_k127_951673_3	264732.Moth_2191	1.029e-209	671.0	COG0651@1|root,COG0651@2|Bacteria,1TREH@1239|Firmicutes,248TK@186801|Clostridia,42EV9@68295|Thermoanaerobacterales	186801|Clostridia	CP	NADH Ubiquinone plastoquinone (Complex I)	hyfB	-	1.6.5.3	ko:K00342,ko:K05568,ko:K12137	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
WLSH2_k127_951673_25	264732.Moth_2192	3.096e-54	197.0	COG1142@1|root,COG1142@2|Bacteria,1VCTD@1239|Firmicutes,24EHU@186801|Clostridia,42GN0@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K12136	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_7
WLSH2_k127_951673_35	926569.ANT_17670	1.085e-25	110.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH2_k127_951687_2	1046724.KB889916_gene277	3.864e-05	50.0	2E585@1|root,3300K@2|Bacteria,1N9MI@1224|Proteobacteria,1SDGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_951687_1	1231185.BAMP01000042_gene1185	1.328e-13	77.0	COG0662@1|root,COG0662@2|Bacteria,1N1YZ@1224|Proteobacteria	1224|Proteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_951687_0	1500257.JQNM01000019_gene2757	2.778e-55	209.0	COG2114@1|root,COG2114@2|Bacteria,1ND4Q@1224|Proteobacteria,2U51W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652,Polyketide_cyc2
WLSH2_k127_9528671_0	316274.Haur_1514	1.749e-95	332.0	COG1680@1|root,COG1680@2|Bacteria,2G7A9@200795|Chloroflexi,376UD@32061|Chloroflexia	32061|Chloroflexia	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_9528671_1	1121272.KB903290_gene4600	6.283e-79	267.0	COG3797@1|root,COG3797@2|Bacteria,2GPDB@201174|Actinobacteria,4DIUT@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
WLSH2_k127_9528671_2	63418.F2PQJ9	5.955e-17	82.0	28JUJ@1|root,2QS8H@2759|Eukaryota,3ADH9@33154|Opisthokonta,3Q32Z@4751|Fungi,3RK4S@4890|Ascomycota,20THT@147545|Eurotiomycetes,3B3WM@33183|Onygenales	4751|Fungi	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WLSH2_k127_9537184_9	926569.ANT_23380	8.9e-129	421.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WLSH2_k127_9537184_21	477974.Daud_1437	3.71e-63	233.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WLSH2_k127_9537184_4	926569.ANT_23360	3.129e-176	563.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH2_k127_9537184_7	926569.ANT_23350	1.523e-148	478.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WLSH2_k127_9537184_3	926569.ANT_23340	2.069e-188	599.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH2_k127_9537184_6	926569.ANT_23330	1.224e-162	530.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
WLSH2_k127_9537184_13	926569.ANT_23310	4.048e-110	364.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WLSH2_k127_9537184_27	926569.ANT_23300	3.266e-31	128.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WLSH2_k127_9537184_14	1382306.JNIM01000001_gene1149	6.144e-106	352.0	COG1092@1|root,COG1092@2|Bacteria,2G60G@200795|Chloroflexi	200795|Chloroflexi	H	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WLSH2_k127_9537184_31	266117.Rxyl_1005	5.589e-24	117.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9537184_29	1382356.JQMP01000003_gene1647	1.678e-28	124.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WLSH2_k127_9537184_0	926569.ANT_25660	0.0	1199.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Big_5,MG1
WLSH2_k127_9537184_22	926569.ANT_30170	1.506e-56	206.0	COG0705@1|root,COG0705@2|Bacteria,2G7BZ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Rhomboid family protein	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
WLSH2_k127_9537184_20	926569.ANT_30180	9.475e-74	253.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WLSH2_k127_9537184_18	459349.CLOAM1351	7.942e-83	285.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	ko:K14696	-	-	-	-	ko00000,ko02000	2.A.4.6	-	-	Cation_efflux,ZT_dimer
WLSH2_k127_9537184_35	318996.AXAZ01000074_gene2177	1.449e-11	77.0	2A8S6@1|root,30XUV@2|Bacteria,1NPUS@1224|Proteobacteria,2UNY7@28211|Alphaproteobacteria,3K3IV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9537184_15	926569.ANT_15920	9.275e-96	320.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
WLSH2_k127_9537184_11	926569.ANT_15930	5.411e-113	371.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
WLSH2_k127_9537184_19	926569.ANT_15940	6.464e-76	268.0	COG1577@1|root,COG1577@2|Bacteria,2G6DY@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
WLSH2_k127_9537184_36	1121285.AUFK01000016_gene3412	7.186e-05	53.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_9537184_23	485916.Dtox_0803	2.051e-35	154.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24N7A@186801|Clostridia,262C9@186807|Peptococcaceae	186801|Clostridia	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WLSH2_k127_9537184_12	221288.JH992901_gene1075	2.793e-112	384.0	COG4191@1|root,COG4191@2|Bacteria,1G1CF@1117|Cyanobacteria,1JH5H@1189|Stigonemataceae	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
WLSH2_k127_9537184_2	373994.Riv7116_6495	1.677e-202	644.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1HMXM@1161|Nostocales	1117|Cyanobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
WLSH2_k127_9537184_28	296591.Bpro_2366	5.032e-29	129.0	COG3594@1|root,COG3594@2|Bacteria,1RGHJ@1224|Proteobacteria,2VS3P@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Acyltransferase family	-	-	-	ko:K21005	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Acyl_transf_3
WLSH2_k127_9537184_17	65393.PCC7424_0063	1.046e-90	306.0	COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,3KJY9@43988|Cyanothece	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
WLSH2_k127_9537184_16	926569.ANT_15450	2.695e-95	321.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WLSH2_k127_9537184_8	926569.ANT_22760	2.264e-140	456.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02532	-	-	-	-	ko00000,ko02000	2.A.1.5	-	-	MFS_1
WLSH2_k127_9537184_24	1449126.JQKL01000009_gene343	2.813e-33	131.0	COG1695@1|root,COG1695@2|Bacteria,1V8K6@1239|Firmicutes,24NN8@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WLSH2_k127_9537184_30	1121405.dsmv_0530	3.08e-26	112.0	COG1320@1|root,COG1320@2|Bacteria	2|Bacteria	P	monovalent cation:proton antiporter activity	mrpG	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
WLSH2_k127_9537184_25	1121405.dsmv_0532	8.115e-32	138.0	COG1863@1|root,COG1863@2|Bacteria	2|Bacteria	P	multisubunit Na H antiporter MnhE subunit	mrpE	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
WLSH2_k127_9537184_5	1121405.dsmv_0533	6.709e-163	533.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,42PD3@68525|delta/epsilon subdivisions,2WJ58@28221|Deltaproteobacteria,2MI5Z@213118|Desulfobacterales	28221|Deltaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
WLSH2_k127_9537184_26	1121405.dsmv_0534	1.253e-31	127.0	COG1006@1|root,COG1006@2|Bacteria,1RH8H@1224|Proteobacteria,42V2H@68525|delta/epsilon subdivisions,2WRNV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05560,ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
WLSH2_k127_9537184_1	1121405.dsmv_0535	6.119e-267	852.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIWK@28221|Deltaproteobacteria,2MI9Z@213118|Desulfobacterales	28221|Deltaproteobacteria	CP	Domain of unknown function (DUF4040)	mrpA	-	-	ko:K05559,ko:K05565	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	DUF4040,MnhB,Proton_antipo_M,Proton_antipo_N
WLSH2_k127_9537184_10	383372.Rcas_3954	1.263e-127	417.0	COG0530@1|root,COG0530@2|Bacteria,2G6GV@200795|Chloroflexi,376V8@32061|Chloroflexia	32061|Chloroflexia	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WLSH2_k127_9554218_5	1536772.R70723_27805	6.515e-48	175.0	COG0454@1|root,COG0456@2|Bacteria,1V81Z@1239|Firmicutes,4HIXF@91061|Bacilli,275IW@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
WLSH2_k127_9554218_4	926569.ANT_19760	6.247e-109	361.0	COG2267@1|root,COG2267@2|Bacteria,2G6KF@200795|Chloroflexi	200795|Chloroflexi	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
WLSH2_k127_9554218_2	926550.CLDAP_20410	2.71e-122	403.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi	2|Bacteria	C	PFAM Cytochrome P450	cyp139A3	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615	-	-	-	-	-	-	-	-	-	-	p450
WLSH2_k127_9554218_7	937777.Deipe_2605	2.259e-38	155.0	COG2324@1|root,COG2324@2|Bacteria,1WI4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM lycopene cyclase domain	-	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
WLSH2_k127_9554218_8	1459636.NTE_03255	3.596e-20	94.0	arCOG00516@1|root,arCOG00516@2157|Archaea,41SQT@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
WLSH2_k127_9554218_3	1321778.HMPREF1982_02748	6.725e-119	398.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,2686Y@186813|unclassified Clostridiales	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WLSH2_k127_9554218_1	926569.ANT_04660	1.657e-160	509.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
WLSH2_k127_9554218_9	637389.Acaty_c1946	4.856e-14	85.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,1RPVP@1236|Gammaproteobacteria,2NCGR@225057|Acidithiobacillales	225057|Acidithiobacillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WLSH2_k127_9554218_0	926569.ANT_04670	8.121e-172	548.0	COG0498@1|root,COG0498@2|Bacteria,2G6D6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_9554218_6	1499967.BAYZ01000048_gene2721	4.997e-42	164.0	COG3464@1|root,COG3464@2|Bacteria,2NRCT@2323|unclassified Bacteria	2|Bacteria	L	SPTR Transposase, IS204 IS1001 IS1096 IS1165 family protein	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_9554218_10	32057.KB217478_gene3219	2.072e-05	49.0	COG3464@1|root,COG3464@2|Bacteria,1G0IQ@1117|Cyanobacteria,1HK29@1161|Nostocales	1117|Cyanobacteria	L	PFAM Transposase, IS204 IS1001 IS1096 IS1165	-	-	-	ko:K07485	-	-	-	-	ko00000	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WLSH2_k127_9577322_0	994573.T472_0206750	8.231e-160	511.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,36DDM@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH2_k127_9577322_22	1265502.KB905929_gene2307	1.292e-24	115.0	COG2020@1|root,COG2020@2|Bacteria,1RECR@1224|Proteobacteria,2WFGY@28216|Betaproteobacteria,4AJM1@80864|Comamonadaceae	28216|Betaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
WLSH2_k127_9577322_6	1035308.AQYY01000001_gene2876	3.516e-67	241.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,261X6@186807|Peptococcaceae	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
WLSH2_k127_9577322_17	1120985.AUMI01000012_gene16	1.905e-35	147.0	2DPHF@1|root,33237@2|Bacteria	2|Bacteria	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
WLSH2_k127_9577322_16	472759.Nhal_1774	7.773e-42	162.0	COG0500@1|root,COG2226@2|Bacteria,1RB5H@1224|Proteobacteria,1SYTI@1236|Gammaproteobacteria,1X2IR@135613|Chromatiales	135613|Chromatiales	Q	Ribosomal protein L11 methyltransferase (PrmA)	-	-	2.1.1.103	ko:K05929	ko00564,map00564	-	R02037,R06868,R06869	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25
WLSH2_k127_9577322_21	1104324.P186_0541	7.078e-28	123.0	COG0778@1|root,arCOG00288@2157|Archaea,2XQJA@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM Nitroreductase	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
WLSH2_k127_9577322_5	1423321.AS29_03125	6.683e-90	308.0	COG2866@1|root,COG2866@2|Bacteria,1V09S@1239|Firmicutes,4HBF2@91061|Bacilli,1ZFKJ@1386|Bacillus	91061|Bacilli	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
WLSH2_k127_9577322_18	762966.HMPREF9439_00902	2.609e-32	139.0	COG4927@1|root,COG4927@2|Bacteria,1NKHP@1224|Proteobacteria,2VKAB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	ko:K19200	ko00311,ko01100,ko01130,map00311,map01100,map01130	-	-	-	ko00000,ko00001,ko01002	-	-	-	AAT
WLSH2_k127_9577322_28	767434.Fraau_0338	3.422e-07	58.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,1S57B@1236|Gammaproteobacteria,1X5IY@135614|Xanthomonadales	135614|Xanthomonadales	CG	Glycosyl transferases, related to UDP-glucuronosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WLSH2_k127_9577322_11	1173026.Glo7428_0528	2.093e-47	183.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WLSH2_k127_9577322_30	1267535.KB906767_gene556	0.000267	45.0	COG1819@1|root,COG1819@2|Bacteria,3Y3H9@57723|Acidobacteria	57723|Acidobacteria	CG	PFAM glycosyl transferase, family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
WLSH2_k127_9577322_10	318464.IO99_06635	1.22e-47	183.0	COG0500@1|root,COG2226@2|Bacteria,1UFKC@1239|Firmicutes,24H53@186801|Clostridia,36I5D@31979|Clostridiaceae	186801|Clostridia	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Ubie_methyltran
WLSH2_k127_9577322_13	1282362.AEAC466_20685	3.801e-47	175.0	COG2050@1|root,COG2050@2|Bacteria,1RH0Z@1224|Proteobacteria,2UC6S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Translation elongation factor P EF-P	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
WLSH2_k127_9577322_19	649638.Trad_1430	5.797e-30	121.0	2E3EN@1|root,32YDN@2|Bacteria,1WKIV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
WLSH2_k127_9577322_20	357808.RoseRS_1993	2.147e-28	116.0	2DQJV@1|root,337C3@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
WLSH2_k127_9577322_9	926560.KE387025_gene4131	1.357e-49	187.0	COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_9577322_23	163908.KB235896_gene2659	6.339e-24	106.0	COG1943@1|root,COG1943@2|Bacteria,1G5NI@1117|Cyanobacteria,1HNAX@1161|Nostocales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WLSH2_k127_9577322_2	621372.ACIH01000158_gene3768	3.031e-131	430.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HC5W@91061|Bacilli,26UR0@186822|Paenibacillaceae	91061|Bacilli	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
WLSH2_k127_9577322_4	861299.J421_3002	1.259e-101	338.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WLSH2_k127_9577322_26	326427.Cagg_2017	4.682e-10	72.0	COG0791@1|root,COG3807@1|root,COG0791@2|Bacteria,COG3807@2|Bacteria,2G99E@200795|Chloroflexi,3759J@32061|Chloroflexia	32061|Chloroflexia	M	SH3, type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
WLSH2_k127_9577322_12	1379698.RBG1_1C00001G1071	2.336e-47	175.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WLSH2_k127_9577322_1	1379698.RBG1_1C00001G1459	5.338e-142	462.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_9577322_14	861299.J421_0312	9.703e-47	172.0	COG2346@1|root,COG2346@2|Bacteria,1ZTRZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
WLSH2_k127_9577322_7	1501230.ET33_18765	5.49e-65	230.0	COG4912@1|root,COG4912@2|Bacteria,1V4WB@1239|Firmicutes,4HFXG@91061|Bacilli,26WYG@186822|Paenibacillaceae	91061|Bacilli	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WLSH2_k127_9577322_24	926569.ANT_23510	1.569e-20	106.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
WLSH2_k127_9577322_25	926569.ANT_23510	1.272e-15	90.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
WLSH2_k127_9577322_8	272557.APE_0122.1	2.69e-55	198.0	COG0537@1|root,arCOG00419@2157|Archaea,2XQK8@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
WLSH2_k127_9577322_3	926569.ANT_26230	1.911e-126	416.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WLSH2_k127_9577322_27	357244.OTBS_1046	5.418e-09	61.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WLSH2_k127_9577322_15	926569.ANT_26250	1.865e-42	160.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
WLSH2_k127_9577322_29	326427.Cagg_2197	1.248e-05	50.0	2EPAC@1|root,33GX3@2|Bacteria,2GB3X@200795|Chloroflexi,377VD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9646780_3	926569.ANT_09420	2.937e-41	160.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.16.1.3,1.5.1.41	ko:K02823,ko:K05368	ko00240,ko00740,ko00860,ko01100,map00240,map00740,map00860,map01100	-	R00097,R05705	RC00126,RC00220	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WLSH2_k127_9646780_2	926569.ANT_18920	2.671e-106	356.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH2_k127_9646780_0	926569.ANT_09430	4.794e-142	457.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
WLSH2_k127_9646780_1	317936.Nos7107_4316	2.175e-132	437.0	COG1253@1|root,COG1253@2|Bacteria,1G16U@1117|Cyanobacteria,1HISP@1161|Nostocales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WLSH2_k127_9646780_4	1499967.BAYZ01000159_gene478	5.09e-33	137.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WLSH2_k127_9702848_2	926550.CLDAP_03420	2.008e-51	190.0	COG0406@1|root,COG0406@2|Bacteria,2G73Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WLSH2_k127_9702848_4	255470.cbdbA1156	7.201e-35	135.0	COG1193@1|root,COG1193@2|Bacteria,2G9VU@200795|Chloroflexi,34DGU@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
WLSH2_k127_9702848_0	1125863.JAFN01000001_gene1857	3.08e-211	672.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH2_k127_9702848_7	795666.MW7_2445	4.443e-08	58.0	COG2104@1|root,COG2104@2|Bacteria,1N9VX@1224|Proteobacteria,2VVYE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM thiamineS protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
WLSH2_k127_9702848_5	639030.JHVA01000001_gene652	5.188e-19	92.0	COG2050@1|root,COG2050@2|Bacteria,3Y57I@57723|Acidobacteria,2JJU4@204432|Acidobacteriia	204432|Acidobacteriia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WLSH2_k127_9702848_6	378806.STAUR_4577	2.186e-08	62.0	COG0727@1|root,COG0727@2|Bacteria,1NJH8@1224|Proteobacteria,432FF@68525|delta/epsilon subdivisions,2XA02@28221|Deltaproteobacteria,2YW1E@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
WLSH2_k127_9702848_1	926569.ANT_16530	2.376e-121	402.0	COG2211@1|root,COG2211@2|Bacteria,2GA8Z@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_9702848_3	880072.Desac_0763	2.444e-38	152.0	COG1145@1|root,COG1145@2|Bacteria,1MW11@1224|Proteobacteria,42NUY@68525|delta/epsilon subdivisions,2WK01@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH2_k127_9735993_1	926569.ANT_22690	1.03e-211	667.0	COG1132@1|root,COG1132@2|Bacteria,2G7KM@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_9735993_0	926569.ANT_22700	1.402e-239	754.0	COG1132@1|root,COG1132@2|Bacteria,2G7KA@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_9735993_2	1200792.AKYF01000020_gene4917	1.484e-41	164.0	COG0454@1|root,COG0454@2|Bacteria,1UJQZ@1239|Firmicutes,4ITDK@91061|Bacilli	91061|Bacilli	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WLSH2_k127_9735993_4	1385935.N836_35430	2.48e-07	53.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9736038_4	926550.CLDAP_01850	1.463e-67	241.0	COG1668@1|root,COG1668@2|Bacteria,2G76A@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
WLSH2_k127_9736038_1	926550.CLDAP_01860	1.32e-96	325.0	COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH2_k127_9736038_5	756883.Halar_2280	9.73e-60	220.0	COG1266@1|root,arCOG02768@2157|Archaea	2157|Archaea	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_9736038_7	1274374.CBLK010000085_gene4656	1.019e-08	63.0	arCOG12597@1|root,2ZBJR@2|Bacteria,1V1R9@1239|Firmicutes,4I88W@91061|Bacilli,271K6@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9736038_6	756883.Halar_2280	4.261e-55	206.0	COG1266@1|root,arCOG02768@2157|Archaea	2157|Archaea	S	metal-dependent membrane protease	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_9736038_3	926550.CLDAP_21020	3.096e-71	246.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH2_k127_9736038_2	926550.CLDAP_21010	1.124e-71	269.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WLSH2_k127_9736038_0	926550.CLDAP_07020	1.821e-103	341.0	COG3293@1|root,COG3293@2|Bacteria,2G7YC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
WLSH2_k127_9808625_12	1462527.CCDM010000004_gene3609	1.533e-26	113.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
WLSH2_k127_9808625_11	765952.PUV_26370	1.503e-31	126.0	2E3V1@1|root,32YSA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9808625_14	485915.Dret_2352	6.582e-23	110.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	Abi
WLSH2_k127_9808625_4	326427.Cagg_0119	3.014e-115	379.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi,3754S@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WLSH2_k127_9808625_8	926569.ANT_28940	1.571e-53	202.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
WLSH2_k127_9808625_16	491205.JARQ01000006_gene2863	0.0001344	46.0	2AC8U@1|root,311TH@2|Bacteria,4PGNY@976|Bacteroidetes,1IHFY@117743|Flavobacteriia,3ZU66@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9808625_5	926569.ANT_00990	6.655e-86	290.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_9808625_7	926569.ANT_01000	1.502e-61	218.0	COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WLSH2_k127_9808625_1	706587.Desti_1075	0.0	1153.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH2_k127_9808625_3	926569.ANT_28990	1.875e-185	589.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WLSH2_k127_9808625_2	926569.ANT_15270	1.253e-291	920.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi	200795|Chloroflexi	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WLSH2_k127_9808625_6	926569.ANT_15280	1.23e-69	240.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi	200795|Chloroflexi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH2_k127_9808625_9	926569.ANT_15290	4.28e-50	183.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9808625_13	1121936.AUHI01000007_gene2349	1.723e-26	109.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
WLSH2_k127_9808625_0	926569.ANT_30500	0.0	1163.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
WLSH2_k127_9808625_10	926550.CLDAP_10960	6.639e-43	161.0	COG2030@1|root,COG2030@2|Bacteria,2G966@200795|Chloroflexi	200795|Chloroflexi	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
WLSH2_k127_9839354_1	272123.Anacy_0598	5.643e-44	163.0	COG0286@1|root,COG0286@2|Bacteria,1G132@1117|Cyanobacteria,1HQG8@1161|Nostocales	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
WLSH2_k127_9839354_5	272123.Anacy_0598	8.456e-05	46.0	COG0286@1|root,COG0286@2|Bacteria,1G132@1117|Cyanobacteria,1HQG8@1161|Nostocales	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
WLSH2_k127_9839354_2	479432.Sros_7420	1.273e-36	153.0	2EBYI@1|root,335XV@2|Bacteria,2IDDP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9839354_4	272123.Anacy_0598	4.199e-06	50.0	COG0286@1|root,COG0286@2|Bacteria,1G132@1117|Cyanobacteria,1HQG8@1161|Nostocales	1117|Cyanobacteria	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
WLSH2_k127_9839354_0	118173.KB235910_gene4671	3.974e-57	204.0	COG4096@1|root,COG4096@2|Bacteria,1G3A8@1117|Cyanobacteria,1H7NP@1150|Oscillatoriales	1117|Cyanobacteria	L	COGs COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,Helicase_C,ResIII
WLSH2_k127_9839354_3	1459636.NTE_02989	5.321e-17	91.0	COG4096@1|root,arCOG00880@2157|Archaea	2157|Archaea	L	Type III restriction enzyme, res subunit	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,Helicase_C,ResIII
WLSH2_k127_9882500_11	1122223.KB890687_gene2435	1.549e-144	467.0	COG0399@1|root,COG0399@2|Bacteria,1WM70@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WLSH2_k127_9882500_18	404380.Gbem_1609	1.464e-124	405.0	COG0110@1|root,COG0110@2|Bacteria,1MZV9@1224|Proteobacteria,42SJ7@68525|delta/epsilon subdivisions,2WPPF@28221|Deltaproteobacteria,43ST6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Hexapeptide repeat of succinyl-transferase	fdtC/fdtA	-	-	-	-	-	-	-	-	-	-	-	FdtA,Hexapep
WLSH2_k127_9882500_22	1211035.CD30_13745	6.802e-108	358.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,3IY27@400634|Lysinibacillus	91061|Bacilli	M	Glycosyl transferase	arnC	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
WLSH2_k127_9882500_39	330214.NIDE1190	1.765e-41	176.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
WLSH2_k127_9882500_26	309801.trd_1313	9.082e-66	252.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH2_k127_9882500_29	485913.Krac_0962	2.907e-64	243.0	COG0515@1|root,COG0515@2|Bacteria,2G8CD@200795|Chloroflexi	200795|Chloroflexi	KLT	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pkinase
WLSH2_k127_9882500_33	394503.Ccel_1554	1.197e-51	197.0	COG1387@1|root,COG1387@2|Bacteria,1VUGT@1239|Firmicutes,25F7D@186801|Clostridia,36UY8@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHB_HEX_C_1,DUF3604
WLSH2_k127_9882500_25	1304874.JAFY01000002_gene577	2.831e-74	269.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
WLSH2_k127_9882500_20	1259795.ARJK01000003_gene1125	1.444e-109	370.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,42FD6@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
WLSH2_k127_9882500_27	926569.ANT_19060	1.639e-64	227.0	COG2518@1|root,COG2518@2|Bacteria,2G6NG@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WLSH2_k127_9882500_43	926569.ANT_05960	2.811e-07	61.0	2ET4Z@1|root,33KP2@2|Bacteria,2G97T@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9882500_37	671143.DAMO_1988	3.69e-44	180.0	COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
WLSH2_k127_9882500_28	530564.Psta_1560	2.209e-64	239.0	2EW1S@1|root,33PF1@2|Bacteria,2J1T5@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9882500_34	269797.Mbar_A2910	1.264e-51	199.0	COG0477@1|root,arCOG00132@2157|Archaea,2XYHV@28890|Euryarchaeota,2NAK2@224756|Methanomicrobia	224756|Methanomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_9882500_36	448385.sce5828	2.88e-46	188.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,42UR3@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,FAD_oxidored
WLSH2_k127_9882500_30	1521187.JPIM01000188_gene1947	1.502e-60	228.0	29YB7@1|root,30K5H@2|Bacteria,2G83K@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9882500_41	1121904.ARBP01000008_gene3289	1.192e-17	96.0	COG2319@1|root,COG2319@2|Bacteria,4PP7D@976|Bacteroidetes,47WB4@768503|Cytophagia	2|Bacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,WD40
WLSH2_k127_9882500_24	926569.ANT_08620	3.875e-92	310.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi	200795|Chloroflexi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WLSH2_k127_9882500_35	926569.ANT_08630	7.892e-47	173.0	COG0295@1|root,COG0295@2|Bacteria,2G7AW@200795|Chloroflexi	200795|Chloroflexi	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
WLSH2_k127_9882500_16	1473546.CH76_09380	1.638e-128	426.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,3IWNF@400634|Lysinibacillus	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
WLSH2_k127_9882500_42	1502852.FG94_03488	1.455e-11	76.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2W1GP@28216|Betaproteobacteria,4764V@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WLSH2_k127_9882500_3	926569.ANT_01410	4.465e-171	541.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WLSH2_k127_9882500_7	926569.ANT_01400	2.833e-159	507.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WLSH2_k127_9882500_5	926569.ANT_31100	1.314e-162	534.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_9882500_19	309803.CTN_0213	1.579e-114	393.0	COG0747@1|root,COG0747@2|Bacteria,2GC5G@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_9882500_21	1382356.JQMP01000003_gene2466	2.103e-109	363.0	COG1173@1|root,COG1173@2|Bacteria,2G85N@200795|Chloroflexi,27YWV@189775|Thermomicrobia	189775|Thermomicrobia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
WLSH2_k127_9882500_23	1382356.JQMP01000003_gene2465	1.063e-98	333.0	COG0601@1|root,COG0601@2|Bacteria,2G7K4@200795|Chloroflexi,27YY8@189775|Thermomicrobia	189775|Thermomicrobia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
WLSH2_k127_9882500_13	309801.trd_0394	2.904e-141	469.0	COG4166@1|root,COG4166@2|Bacteria,2GBUU@200795|Chloroflexi,27YZK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WLSH2_k127_9882500_12	326427.Cagg_2964	5.457e-144	464.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WLSH2_k127_9882500_14	926550.CLDAP_11120	6.751e-140	451.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WLSH2_k127_9882500_17	713587.THITH_04475	2.697e-127	415.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,1RSGQ@1236|Gammaproteobacteria,1X07D@135613|Chromatiales	135613|Chromatiales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WLSH2_k127_9882500_9	926550.CLDAP_11010	3.066e-147	471.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WLSH2_k127_9882500_10	926550.CLDAP_11020	5.277e-147	478.0	COG1173@1|root,COG1173@2|Bacteria,2G841@200795|Chloroflexi	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
WLSH2_k127_9882500_15	926550.CLDAP_11030	1.732e-133	436.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_9882500_6	187272.Mlg_2180	6.767e-161	537.0	COG0747@1|root,COG3889@1|root,COG0747@2|Bacteria,COG3889@2|Bacteria,1R6EI@1224|Proteobacteria,1SKRH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_9882500_38	1033744.CAEL01000023_gene279	2.183e-43	165.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,22HFM@1570339|Peptoniphilaceae	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WLSH2_k127_9882500_1	1128398.Curi_c03110	1.86e-263	848.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,267U0@186813|unclassified Clostridiales	186801|Clostridia	L	UvrD-like helicase C-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH2_k127_9882500_40	272563.CD630_08810	1.398e-19	100.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,25R71@186804|Peptostreptococcaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH2_k127_9882500_4	756272.Plabr_1636	4.28e-167	542.0	COG4805@1|root,COG4805@2|Bacteria,2IY48@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WLSH2_k127_9882500_32	671143.DAMO_0654	9.633e-52	188.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
WLSH2_k127_9882500_2	671143.DAMO_0652	3.723e-219	693.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_9882500_0	555088.DealDRAFT_2538	6.341e-281	872.0	COG1960@1|root,COG1960@2|Bacteria,1V03D@1239|Firmicutes,24A8N@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
WLSH2_k127_9882500_8	926550.CLDAP_38240	1.721e-148	475.0	COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3,6.4.1.4	ko:K01969,ko:K15052	ko00280,ko00720,ko01100,ko01200,map00280,map00720,map01100,map01200	M00036,M00376	R01859,R04138	RC00097,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH2_k127_9943953_4	696125.BARCL_1237	3.024e-10	72.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,48T85@772|Bartonellaceae	28211|Alphaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WLSH2_k127_9943953_1	118166.JH976537_gene1045	1.087e-26	124.0	COG1511@1|root,COG2319@1|root,COG1511@2|Bacteria,COG2319@2|Bacteria,1GHUJ@1117|Cyanobacteria,1HHZK@1150|Oscillatoriales	1117|Cyanobacteria	S	GUN4-like	-	-	-	-	-	-	-	-	-	-	-	-	GUN4
WLSH2_k127_9943953_5	526225.Gobs_0746	1.312e-08	58.0	COG1262@1|root,COG3170@1|root,COG1262@2|Bacteria,COG3170@2|Bacteria,2IBYZ@201174|Actinobacteria	201174|Actinobacteria	NU	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	PknH_C,TIR_2
WLSH2_k127_9943953_2	111781.Lepto7376_1188	6.451e-18	93.0	2DD5V@1|root,2ZGNZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9943953_0	1521187.JPIM01000229_gene2475	2.116e-189	607.0	COG5421@1|root,COG5421@2|Bacteria,2G7SD@200795|Chloroflexi,376XS@32061|Chloroflexia	32061|Chloroflexia	L	COGs COG5421 Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9943953_3	1385514.N782_19560	3.209e-11	68.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4IV7Y@91061|Bacilli,2Y8NK@289201|Pontibacillus	91061|Bacilli	C	Aconitate hydratase	thrS	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WLSH2_k127_9951688_11	706587.Desti_1778	3.703e-33	140.0	COG2199@1|root,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2X7CV@28221|Deltaproteobacteria,2MS14@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	TIGRFAM diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,PAS_4,Response_reg
WLSH2_k127_9951688_12	926560.KE387023_gene3186	2.026e-16	87.0	COG4392@1|root,COG4392@2|Bacteria,1WNCD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
WLSH2_k127_9951688_5	891968.Anamo_0736	5.649e-71	247.0	COG1296@1|root,COG1296@2|Bacteria,3TBT2@508458|Synergistetes	508458|Synergistetes	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
WLSH2_k127_9951688_9	391625.PPSIR1_06783	3.636e-51	188.0	2DNQT@1|root,32YKZ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
WLSH2_k127_9951688_13	391625.PPSIR1_06783	2.409e-10	63.0	2DNQT@1|root,32YKZ@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
WLSH2_k127_9951688_8	926569.ANT_29460	1.432e-55	199.0	COG0757@1|root,COG0757@2|Bacteria,2G70K@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
WLSH2_k127_9951688_1	926569.ANT_01920	2.489e-142	468.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
WLSH2_k127_9951688_0	926569.ANT_01910	1.177e-162	522.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
WLSH2_k127_9951688_6	926569.ANT_01900	1.007e-69	246.0	COG0169@1|root,COG0169@2|Bacteria,2G6FG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_dh_N
WLSH2_k127_9951688_4	1120973.AQXL01000134_gene1554	3.889e-134	440.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli	91061|Bacilli	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
WLSH2_k127_9951688_7	926569.ANT_01880	3.777e-66	235.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi	200795|Chloroflexi	E	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
WLSH2_k127_9951688_3	926569.ANT_01870	2.114e-135	440.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WLSH2_k127_9951688_2	926569.ANT_01870	1.106e-140	455.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WLSH2_k127_9951688_10	751945.Theos_1561	5.865e-41	154.0	COG4401@1|root,COG4401@2|Bacteria,1WJZD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
## 5061 queries scanned
## Total time (seconds): 12.498983144760132
## Rate: 404.91 q/s