## Tue Dec 16 21:25:57 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WLSH2_bin.69.fa -m mmseqs --itype genome -o WLSH2_bin.69 --output_dir /data/result/bins/wyx/egg/WLSH2_bin.69 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WLSH2_k127_10016808_3	76114.ebA3373	3.577e-30	124.0	COG2267@1|root,COG2267@2|Bacteria,1QVBZ@1224|Proteobacteria,2VNI1@28216|Betaproteobacteria,2KUFT@206389|Rhodocyclales	206389|Rhodocyclales	I	Alpha beta hydrolase	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6
WLSH2_k127_10016808_2	1123073.KB899241_gene2776	3.301e-71	253.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,1RQ7V@1236|Gammaproteobacteria,1X44X@135614|Xanthomonadales	135614|Xanthomonadales	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
WLSH2_k127_10016808_1	375286.mma_0185	4.862e-109	362.0	2C7F6@1|root,2Z8AK@2|Bacteria,1PEE5@1224|Proteobacteria,2VKQ6@28216|Betaproteobacteria,476M3@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10016808_4	1469245.JFBG01000027_gene1443	2.191e-28	123.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,1SF74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WLSH2_k127_10016808_0	760117.JN27_10735	2.644e-115	386.0	2DBPG@1|root,2ZA96@2|Bacteria,1QVNF@1224|Proteobacteria,2VP5D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4382
WLSH2_k127_10022102_4	420662.Mpe_A0077	1.104e-20	99.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGRW@28216|Betaproteobacteria,1KK18@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	two-component sensor kinase	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
WLSH2_k127_10022102_2	204773.HEAR2689	3.485e-78	269.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,476X2@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_10022102_0	1054213.HMPREF9946_04357	1.888e-223	702.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JRDI@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH2_k127_10022102_1	1380394.JADL01000013_gene696	7.825e-97	324.0	COG2175@1|root,COG2175@2|Bacteria,1P6UZ@1224|Proteobacteria,2TTJB@28211|Alphaproteobacteria,2JYSV@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
WLSH2_k127_10022102_3	1144312.PMI09_04995	9.346e-71	246.0	COG0684@1|root,COG0684@2|Bacteria,1QSHP@1224|Proteobacteria,2U948@28211|Alphaproteobacteria,4BAVZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
WLSH2_k127_1004255_0	1288494.EBAPG3_7870	1.415e-155	500.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,371M0@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
WLSH2_k127_1004255_2	748247.AZKH_0440	1.299e-62	218.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2VQGE@28216|Betaproteobacteria,2KW8Z@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
WLSH2_k127_1004255_4	1163617.SCD_n00843	2.644e-48	177.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WLSH2_k127_1004255_3	1123320.KB889640_gene4463	4.834e-57	205.0	COG2350@1|root,COG2350@2|Bacteria,2GM07@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
WLSH2_k127_1004255_1	1120983.KB894571_gene2468	6.67e-122	402.0	COG1073@1|root,COG1073@2|Bacteria,1PJHR@1224|Proteobacteria,2U2QB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1004255_5	323848.Nmul_A0013	5.756e-28	117.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,372GP@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WLSH2_k127_1019250_2	1123392.AQWL01000002_gene2069	2.012e-140	452.0	COG1216@1|root,COG1216@2|Bacteria,1N72Z@1224|Proteobacteria,2W93K@28216|Betaproteobacteria,1KSXM@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_1019250_6	29581.BW37_03157	3.456e-66	237.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721,ko:K07011,ko:K20444	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
WLSH2_k127_1019250_7	29581.BW37_03158	8.353e-66	231.0	COG1898@1|root,COG1898@2|Bacteria,1RGRQ@1224|Proteobacteria	1224|Proteobacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
WLSH2_k127_1019250_1	1123393.KB891330_gene784	2.081e-150	484.0	COG0438@1|root,COG0438@2|Bacteria,1NE5D@1224|Proteobacteria,2VWY9@28216|Betaproteobacteria,1KSG1@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
WLSH2_k127_1019250_0	1123393.KB891330_gene785	2.523e-153	497.0	COG2327@1|root,COG2327@2|Bacteria,1Q1HX@1224|Proteobacteria,2VZYJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
WLSH2_k127_1019250_9	1121405.dsmv_0731	7.288e-44	176.0	2AK27@1|root,31ARV@2|Bacteria,1REZR@1224|Proteobacteria,42W34@68525|delta/epsilon subdivisions,2WRFM@28221|Deltaproteobacteria,2MNUM@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1019250_8	1541065.JRFE01000028_gene3334	1.786e-47	188.0	COG0745@1|root,COG0745@2|Bacteria,1GQR9@1117|Cyanobacteria,3VMJN@52604|Pleurocapsales	1117|Cyanobacteria	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1019250_3	118168.MC7420_1744	2.255e-139	451.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K16555	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	DUF2972,Glyco_tran_WbsX,Glycos_transf_2
WLSH2_k127_1019250_5	292415.Tbd_0312	2.389e-90	302.0	COG2227@1|root,COG2227@2|Bacteria,1NBIU@1224|Proteobacteria	1224|Proteobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Methyltransf_23
WLSH2_k127_1019250_4	1123392.AQWL01000002_gene2072	4.613e-107	348.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,2VN03@28216|Betaproteobacteria,1KST6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
WLSH2_k127_10416475_4	1380355.JNIJ01000010_gene1443	1.653e-143	463.0	COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria,3JWB9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
WLSH2_k127_10416475_12	1038859.AXAU01000008_gene2024	5.738e-71	244.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U4QB@28211|Alphaproteobacteria,3JRDA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
WLSH2_k127_10416475_0	1207063.P24_05264	3.623e-179	571.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,2JQ0Z@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
WLSH2_k127_10416475_2	1304877.KI519399_gene2903	1.08e-155	503.0	COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH2_k127_10416475_6	1000565.METUNv1_04021	1.135e-114	381.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,2KURQ@206389|Rhodocyclales	28216|Betaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
WLSH2_k127_10416475_9	795666.MW7_1388	4.933e-111	367.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VMN7@28216|Betaproteobacteria,1K3PN@119060|Burkholderiaceae	28216|Betaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase	gyaR	-	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_10416475_7	1000565.METUNv1_04017	3.99e-112	370.0	COG0679@1|root,COG0679@2|Bacteria,1RCAI@1224|Proteobacteria,2VVPY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
WLSH2_k127_10416475_10	76114.ebA3883	3.906e-91	310.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VHAW@28216|Betaproteobacteria,2KVG1@206389|Rhodocyclales	206389|Rhodocyclales	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	tsaR	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WLSH2_k127_10416475_3	159450.NH14_09555	2.664e-153	491.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2VNJZ@28216|Betaproteobacteria,1K33G@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
WLSH2_k127_10416475_14	582744.Msip34_2411	2.384e-49	181.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,2WGT1@28216|Betaproteobacteria,2KMWZ@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_10416475_11	265072.Mfla_0357	1.199e-85	295.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2VHTD@28216|Betaproteobacteria,2KM94@206350|Nitrosomonadales	206350|Nitrosomonadales	S	molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
WLSH2_k127_10416475_18	305700.B447_10473	4.77e-29	123.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,2KW96@206389|Rhodocyclales	206389|Rhodocyclales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
WLSH2_k127_10416475_16	1415780.JPOG01000001_gene1475	1.066e-46	172.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1X72T@135614|Xanthomonadales	135614|Xanthomonadales	FG	Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WLSH2_k127_10416475_13	1125973.JNLC01000011_gene592	7.568e-62	227.0	COG0673@1|root,COG0673@2|Bacteria,1QSNV@1224|Proteobacteria,2TUMB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_10416475_8	1120983.KB894577_gene3576	1.631e-111	369.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2U1NZ@28211|Alphaproteobacteria,1JQNJ@119043|Rhodobiaceae	28211|Alphaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.28,1.1.1.29,1.1.1.399,1.1.1.95	ko:K00018,ko:K00058,ko:K03778	ko00260,ko00620,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00620,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020,M00346	R00704,R00717,R01388,R01513	RC00031,RC00042,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
WLSH2_k127_10416475_17	1120983.KB894577_gene3580	3.397e-38	146.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	1.13.11.4,4.1.2.17	ko:K00450,ko:K01628	ko00051,ko00350,ko01100,ko01120,map00051,map00350,map01100,map01120	-	R02262,R02656	RC00603,RC00604,RC00764	ko00000,ko00001,ko01000	-	-	-	Cupin_2,Lipase_GDSL_2
WLSH2_k127_10416475_5	1120983.KB894577_gene3579	7.562e-120	391.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,2U6JP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WLSH2_k127_10416475_1	1120983.KB894577_gene3578	8.456e-160	512.0	COG0673@1|root,COG0673@2|Bacteria,1PGFP@1224|Proteobacteria,2V8DN@28211|Alphaproteobacteria,1JQA3@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_10416475_15	1120983.KB894577_gene3577	3.423e-47	174.0	COG1802@1|root,COG1802@2|Bacteria,1RDQP@1224|Proteobacteria,2URM2@28211|Alphaproteobacteria,1JQND@119043|Rhodobiaceae	28211|Alphaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WLSH2_k127_10533296_0	1121004.ATVC01000001_gene426	1.064e-192	608.0	COG3211@1|root,COG3211@2|Bacteria,1MU8T@1224|Proteobacteria,2VK2V@28216|Betaproteobacteria,2KQU2@206351|Neisseriales	206351|Neisseriales	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
WLSH2_k127_10533296_3	1279019.ARQK01000047_gene1047	5.039e-52	187.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S7F0@1236|Gammaproteobacteria,1WYEG@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH2_k127_10533296_1	477184.KYC_25198	1.238e-79	279.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VMFM@28216|Betaproteobacteria,3T1X5@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_10533296_2	1123060.JONP01000024_gene2528	4.931e-64	225.0	COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,2JY55@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WLSH2_k127_10550857_8	1123393.KB891333_gene2528	1.731e-24	108.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria,1KT1M@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
WLSH2_k127_10550857_6	1221522.B723_12615	3.887e-37	143.0	2CBFC@1|root,32RYI@2|Bacteria,1N0T4@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10550857_4	1488328.JMCL01000101_gene3896	7.96e-43	165.0	2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,1SGTK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10550857_3	400682.PAC_15704163	1.831e-51	187.0	COG1495@1|root,2SDDI@2759|Eukaryota,3AE24@33154|Opisthokonta,3BWEU@33208|Metazoa	33208|Metazoa	O	Disulfide bond formation protein DsbB	-	-	-	-	-	-	-	-	-	-	-	-	DsbB
WLSH2_k127_10550857_9	713586.KB900536_gene1873	1.938e-13	73.0	COG5481@1|root,COG5481@2|Bacteria,1QB94@1224|Proteobacteria,1SHNI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
WLSH2_k127_10550857_2	935840.JAEQ01000023_gene4306	2.968e-55	197.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U7NJ@28211|Alphaproteobacteria,43R40@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WLSH2_k127_10550857_0	1298867.AUES01000046_gene4084	1.02e-223	718.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,3JRND@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_10550857_1	384765.SIAM614_15897	8.141e-61	217.0	COG0546@1|root,COG0546@2|Bacteria,1REXF@1224|Proteobacteria,2VG24@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	HAD-hyrolase-like	MA20_36165	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WLSH2_k127_10550857_7	865861.AZSU01000003_gene1836	4.15e-32	130.0	COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,36JJ0@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
WLSH2_k127_10550857_5	1100720.ALKN01000035_gene1001	6.843e-38	144.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
WLSH2_k127_10619184_5	1266925.JHVX01000005_gene1888	7.75e-59	210.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,3732Y@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
WLSH2_k127_10619184_4	159087.Daro_0843	1.286e-68	248.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2VHMQ@28216|Betaproteobacteria,2KX76@206389|Rhodocyclales	206389|Rhodocyclales	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WLSH2_k127_10619184_7	1458275.AZ34_02025	9.158e-10	64.0	2CE4Y@1|root,34C4Z@2|Bacteria,1P3HD@1224|Proteobacteria,2W4H6@28216|Betaproteobacteria,4AI8C@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10619184_3	1454004.AW11_00275	7.683e-94	314.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,1KPYR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WLSH2_k127_10619184_2	1266925.JHVX01000005_gene1890	1.788e-144	484.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,372GX@32003|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WLSH2_k127_10619184_6	1266925.JHVX01000010_gene1397	2.273e-55	212.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria,3729Q@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
WLSH2_k127_10619184_0	1131553.JIBI01000002_gene1792	2.679e-216	687.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,371XW@32003|Nitrosomonadales	28216|Betaproteobacteria	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH2_k127_10619184_1	395495.Lcho_2217	3.775e-187	591.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,1KKFD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	polyphosphate kinase	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
WLSH2_k127_10619184_8	1437824.BN940_11136	0.0001951	44.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,3T2CZ@506|Alcaligenaceae	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH2_k127_10623274_2	296591.Bpro_0284	6.478e-70	249.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_10623274_3	667632.KB890180_gene796	1.552e-65	237.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2VJX2@28216|Betaproteobacteria,1K6WZ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	mdlA	-	5.1.2.2	ko:K01781	ko00627,ko01120,map00627,map01120	-	R03791,R04161	RC00998	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_10623274_4	395019.Bmul_5339	9.675e-62	218.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,2VQUA@28216|Betaproteobacteria,1K6XY@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	SMART metal-dependent phosphohydrolase, HD region	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
WLSH2_k127_10623274_0	330214.NIDE0058	2.489e-232	735.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
WLSH2_k127_10623274_1	1123368.AUIS01000008_gene2237	3.511e-194	610.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T90P@1236|Gammaproteobacteria,2NDQR@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
WLSH2_k127_10623274_5	1304883.KI912532_gene2329	5.487e-56	198.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,2VRE4@28216|Betaproteobacteria,2KWM9@206389|Rhodocyclales	206389|Rhodocyclales	S	AMMECR1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
WLSH2_k127_10710265_4	580332.Slit_2928	1.816e-115	376.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,44VA6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WLSH2_k127_10710265_2	1144319.PMI16_04778	2.235e-173	554.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2VHFA@28216|Betaproteobacteria,473ET@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_10710265_1	580332.Slit_2926	2.185e-221	694.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,44V04@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Nitrogen metabolism transcriptional regulator, NtrC, Fis Family	ntrC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH2_k127_10710265_3	62928.azo0736	8.034e-125	409.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KUZZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
WLSH2_k127_10710265_7	1121035.AUCH01000016_gene2142	1.371e-30	130.0	2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria,2KWKW@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
WLSH2_k127_10710265_0	1163617.SCD_n00194	6.717e-270	834.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria	28216|Betaproteobacteria	E	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WLSH2_k127_10710265_6	640081.Dsui_1047	2.312e-60	212.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,2KWCV@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_10710265_8	443152.MDG893_11041	7.522e-07	57.0	COG0388@1|root,COG1247@1|root,COG0388@2|Bacteria,COG1247@2|Bacteria,1MX4I@1224|Proteobacteria,1RP30@1236|Gammaproteobacteria,4648Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
WLSH2_k127_10710265_5	1005048.CFU_0842	2.538e-70	241.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,473CE@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WLSH2_k127_10736513_0	1163617.SCD_n00393	4.923e-211	662.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
WLSH2_k127_10736513_1	1163617.SCD_n00396	7.091e-197	635.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
WLSH2_k127_10736513_2	1163617.SCD_n00397	2.258e-31	126.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria	28216|Betaproteobacteria	GM	epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
WLSH2_k127_10743159_1	1123368.AUIS01000003_gene1788	2.892e-106	354.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria	1224|Proteobacteria	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WLSH2_k127_10743159_0	95619.PM1_0226315	4.744e-117	381.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH2_k127_10743159_2	580332.Slit_2777	9.72e-105	350.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria	28216|Betaproteobacteria	O	serine protease	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
WLSH2_k127_10763086_3	1298867.AUES01000046_gene4088	7.934e-95	316.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,3JXHZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_10763086_1	1125973.JNLC01000018_gene2319	1.103e-106	355.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2U8QU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_10763086_0	1125973.JNLC01000018_gene2320	2.332e-214	677.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
WLSH2_k127_10763086_7	398527.Bphyt_2223	1.636e-34	146.0	COG0346@1|root,COG0346@2|Bacteria,1PK3B@1224|Proteobacteria,2W8DQ@28216|Betaproteobacteria,1K798@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
WLSH2_k127_10763086_6	398525.KB900701_gene6347	1.317e-42	165.0	COG0725@1|root,COG0725@2|Bacteria,1NY9R@1224|Proteobacteria,2U095@28211|Alphaproteobacteria,3JWYM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
WLSH2_k127_10763086_9	713586.KB900536_gene575	3.404e-15	80.0	2EJUZ@1|root,33DJM@2|Bacteria,1NIYD@1224|Proteobacteria,1SGV4@1236|Gammaproteobacteria,1WZJR@135613|Chromatiales	135613|Chromatiales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
WLSH2_k127_10763086_4	864051.BurJ1DRAFT_4699	1.462e-87	302.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2WEGN@28216|Betaproteobacteria,1KKYV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	-	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WLSH2_k127_10763086_2	1504672.669784884	1.103e-105	357.0	COG4591@1|root,COG4591@2|Bacteria,1Q2BY@1224|Proteobacteria,2VHS2@28216|Betaproteobacteria,4AG6A@80864|Comamonadaceae	28216|Betaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WLSH2_k127_10763086_5	1504672.669784885	8.631e-46	170.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VMY1@28216|Betaproteobacteria,4AGPA@80864|Comamonadaceae	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
WLSH2_k127_10775573_14	1288494.EBAPG3_31110	1.542e-47	172.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,3720W@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH2_k127_10775573_7	1125973.JNLC01000012_gene749	8.987e-127	418.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,3JSP6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	MA20_00655	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
WLSH2_k127_10775573_13	396588.Tgr7_1268	2.946e-61	222.0	COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,1S05R@1236|Gammaproteobacteria,1WXBW@135613|Chromatiales	135613|Chromatiales	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10775573_2	396588.Tgr7_1267	4.079e-222	699.0	COG0247@1|root,COG1145@1|root,COG0247@2|Bacteria,COG1145@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1WWK6@135613|Chromatiales	135613|Chromatiales	C	PFAM Cysteine-rich	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
WLSH2_k127_10775573_10	1173026.Glo7428_2528	2.374e-83	287.0	COG2816@1|root,COG2816@2|Bacteria,1G3EM@1117|Cyanobacteria	1117|Cyanobacteria	L	Belongs to the Nudix hydrolase family. NudC subfamily	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
WLSH2_k127_10775573_5	497321.C664_14259	8.384e-139	449.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,2KV4P@206389|Rhodocyclales	206389|Rhodocyclales	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
WLSH2_k127_10775573_9	1131553.JIBI01000001_gene1481	8.959e-89	299.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,3726Z@32003|Nitrosomonadales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
WLSH2_k127_10775573_12	1485544.JQKP01000001_gene1237	1.689e-72	247.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria,44VTC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
WLSH2_k127_10775573_11	580332.Slit_1510	7.265e-83	282.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,44VMR@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH2_k127_10775573_8	228410.NE0138	1.639e-92	310.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,37229@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
WLSH2_k127_10775573_6	1288494.EBAPG3_970	6.951e-128	424.0	COG0741@1|root,COG0741@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,372NP@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Lysin motif	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
WLSH2_k127_10775573_0	1163617.SCD_n01163	2.86e-265	832.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	dppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WLSH2_k127_10775573_3	323848.Nmul_A2332	9.747e-186	599.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,372BM@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_10775573_4	1049564.TevJSym_au00340	1.621e-152	492.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1J598@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Oligopeptide transport system permease protein OppB	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_10775573_1	1163617.SCD_n01160	4.15e-261	816.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Extracellular solute-binding protein	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
WLSH2_k127_10799962_0	323848.Nmul_A0699	2.853e-181	571.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,371MB@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
WLSH2_k127_10799962_2	1266925.JHVX01000003_gene432	1.15e-62	221.0	COG0822@1|root,COG0822@2|Bacteria,1PC9F@1224|Proteobacteria,2VS65@28216|Betaproteobacteria,372KK@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WLSH2_k127_10799962_1	323848.Nmul_A0701	4.203e-80	270.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2VQ83@28216|Betaproteobacteria,371PF@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Scaffold protein Nfu/NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
WLSH2_k127_10804505_0	1123393.KB891316_gene1151	9.901e-42	155.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2W9BR@28216|Betaproteobacteria,1KSCW@119069|Hydrogenophilales	119069|Hydrogenophilales	E	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
WLSH2_k127_10804505_1	765910.MARPU_02200	1.072e-35	142.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1WYQF@135613|Chromatiales	135613|Chromatiales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
WLSH2_k127_10804505_3	1249627.D779_0956	4.625e-28	121.0	COG4970@1|root,COG4970@2|Bacteria,1N7RS@1224|Proteobacteria,1SCFB@1236|Gammaproteobacteria,1WYQF@135613|Chromatiales	135613|Chromatiales	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
WLSH2_k127_10804505_4	1123393.KB891316_gene1149	7.768e-26	112.0	COG4967@1|root,COG4967@2|Bacteria,1N6TG@1224|Proteobacteria,2VX03@28216|Betaproteobacteria,1KTHP@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WLSH2_k127_10804505_2	340.xcc-b100_1669	2.051e-35	151.0	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1S7JH@1236|Gammaproteobacteria,1X6RM@135614|Xanthomonadales	135614|Xanthomonadales	NU	pilus assembly protein PilW	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
WLSH2_k127_10804505_5	1042377.AFPJ01000029_gene539	5.048e-12	73.0	COG4726@1|root,COG4726@2|Bacteria,1N7KP@1224|Proteobacteria,1SCM5@1236|Gammaproteobacteria,46970@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	PilX N-terminal	pilX	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilX,PilX_N
WLSH2_k127_10855814_2	1205680.CAKO01000029_gene4997	5.267e-194	610.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,2JSIF@204441|Rhodospirillales	204441|Rhodospirillales	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2,Pyr_redox_3
WLSH2_k127_10855814_7	864051.BurJ1DRAFT_4570	2.504e-06	56.0	COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2VVC1@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
WLSH2_k127_10855814_5	977880.RALTA_B1677	2.675e-87	299.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_10855814_0	1131553.JIBI01000015_gene643	1.995e-257	805.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,372TA@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_10855814_1	1288494.EBAPG3_5120	1.223e-199	630.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,372F1@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH2_k127_10855814_4	1163617.SCD_n00055	7e-116	383.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
WLSH2_k127_10855814_6	1288494.EBAPG3_5100	3.17e-42	160.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,3738A@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
WLSH2_k127_10855814_3	1123487.KB892867_gene1012	1.126e-166	532.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KV8K@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH2_k127_10886339_0	713586.KB900536_gene306	5.707e-134	434.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales	135613|Chromatiales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WLSH2_k127_10886339_1	519989.ECTPHS_10671	3.398e-93	312.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1WVXB@135613|Chromatiales	135613|Chromatiales	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WLSH2_k127_10920655_17	338969.Rfer_0960	1.083e-57	209.0	COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_10920655_21	264462.Bd1337	1.198e-34	135.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,430NN@68525|delta/epsilon subdivisions,2MT6T@213481|Bdellovibrionales,2WVYS@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
WLSH2_k127_10920655_9	342113.DM82_241	5.695e-90	307.0	COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,2VJWC@28216|Betaproteobacteria,1JZY5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WLSH2_k127_10920655_11	1122223.KB890687_gene2436	2.511e-76	259.0	COG0225@1|root,COG0225@2|Bacteria,1WK2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WLSH2_k127_10920655_2	1392838.AWNM01000046_gene1990	1.772e-162	517.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,3T1DZ@506|Alcaligenaceae	28216|Betaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
WLSH2_k127_10920655_14	330214.NIDE4360	1.056e-66	245.0	COG0225@1|root,COG0225@2|Bacteria	2|Bacteria	O	peptide-methionine (S)-S-oxide reductase activity	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WLSH2_k127_10920655_6	1255043.TVNIR_2414	6.807e-107	358.0	COG0709@1|root,COG1252@1|root,COG0709@2|Bacteria,COG1252@2|Bacteria,1MWFG@1224|Proteobacteria,1RQ5Q@1236|Gammaproteobacteria,1X13W@135613|Chromatiales	135613|Chromatiales	CE	AIR synthase related protein, N-terminal domain	-	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
WLSH2_k127_10920655_0	1288494.EBAPG3_4680	1.834e-192	607.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,3723P@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
WLSH2_k127_10920655_4	1163617.SCD_n02515	8.941e-139	453.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH2_k127_10920655_5	1163617.SCD_n02516	8.625e-130	423.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
WLSH2_k127_10920655_18	159087.Daro_0653	1.364e-55	197.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,2KWB8@206389|Rhodocyclales	206389|Rhodocyclales	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
WLSH2_k127_10920655_20	580332.Slit_2453	7.491e-50	180.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,44WIP@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WLSH2_k127_10920655_19	580332.Slit_2454	1.78e-55	203.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria,44WF0@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_10920655_1	1123392.AQWL01000022_gene2179	1.287e-177	561.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,1KRDK@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WLSH2_k127_10920655_16	1131553.JIBI01000042_gene2010	1.065e-60	214.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,3730F@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WLSH2_k127_10920655_12	1000565.METUNv1_02883	9.425e-74	250.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,2KW9N@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WLSH2_k127_10920655_13	580332.Slit_2472	7.528e-73	253.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,44W6B@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WLSH2_k127_10920655_15	265072.Mfla_0380	8.656e-63	220.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,2KMKZ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WLSH2_k127_10920655_10	1163617.SCD_n02524	3.968e-85	286.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
WLSH2_k127_10920655_7	292415.Tbd_2222	4.423e-105	347.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,1KREE@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
WLSH2_k127_10920655_3	522306.CAP2UW1_1154	2.185e-152	492.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,1KPU3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
WLSH2_k127_10920655_8	1163617.SCD_n02532	2.924e-100	331.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WLSH2_k127_10920655_22	1121035.AUCH01000009_gene894	8.332e-30	119.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,2KVHH@206389|Rhodocyclales	206389|Rhodocyclales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
WLSH2_k127_10922208_3	76114.ebA4944	2.248e-51	188.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,2KVCU@206389|Rhodocyclales	206389|Rhodocyclales	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
WLSH2_k127_10922208_4	292415.Tbd_0089	8.571e-51	188.0	COG0847@1|root,COG0847@2|Bacteria,1RCPS@1224|Proteobacteria,2WEVE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
WLSH2_k127_10922208_0	883080.HMPREF9697_01679	1.54e-269	846.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,3K3CR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_10922208_2	1121861.KB899926_gene2599	3.295e-125	413.0	COG0477@1|root,COG2814@2|Bacteria,1P3S4@1224|Proteobacteria,2TVAQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_10922208_1	640081.Dsui_1636	4.415e-207	659.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VKMW@28216|Betaproteobacteria,2KV2G@206389|Rhodocyclales	206389|Rhodocyclales	I	Poly-beta-hydroxybutyrate	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
WLSH2_k127_10923715_1	323098.Nwi_1985	2.61e-124	406.0	28IUD@1|root,2Z8T4@2|Bacteria,1QZHS@1224|Proteobacteria,2UD7F@28211|Alphaproteobacteria,3K09B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	CsoS2_M
WLSH2_k127_10923715_0	75379.Tint_0118	3.63e-208	657.0	28K6U@1|root,2Z9V7@2|Bacteria,1MYVN@1224|Proteobacteria,2VNQ9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxysome Shell Carbonic Anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	CsoSCA
WLSH2_k127_10923715_2	75379.Tint_0119	2.719e-44	161.0	COG4576@1|root,COG4576@2|Bacteria,1MZNS@1224|Proteobacteria,2VUR7@28216|Betaproteobacteria	28216|Betaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
WLSH2_k127_10923715_3	75379.Tint_0120	1.541e-24	108.0	COG4576@1|root,COG4576@2|Bacteria,1N7B1@1224|Proteobacteria,2VX39@28216|Betaproteobacteria	28216|Betaproteobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
WLSH2_k127_10977443_1	1123368.AUIS01000015_gene2640	3.078e-80	271.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria,2NC8V@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
WLSH2_k127_10977443_0	1123393.KB891317_gene2324	0.0	1007.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,1KREG@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WLSH2_k127_11006065_1	1158182.KB905021_gene535	5.845e-67	233.0	COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,1S2MS@1236|Gammaproteobacteria,1WY6J@135613|Chromatiales	135613|Chromatiales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	-
WLSH2_k127_11006065_3	1266908.AQPB01000061_gene1235	9.246e-15	74.0	2E4KB@1|root,32ZFA@2|Bacteria,1N6R9@1224|Proteobacteria,1SFP8@1236|Gammaproteobacteria,1WZH8@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11006065_0	396588.Tgr7_0353	5.11e-215	673.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1WWF2@135613|Chromatiales	135613|Chromatiales	P	Belongs to the sulfate adenylyltransferase family	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
WLSH2_k127_11006065_2	637390.AFOH01000137_gene1756	3.606e-47	182.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,1S4SH@1236|Gammaproteobacteria,2NCF7@225057|Acidithiobacillales	225057|Acidithiobacillales	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WLSH2_k127_11054195_1	1128421.JAGA01000002_gene62	2.011e-58	211.0	COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria	2|Bacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
WLSH2_k127_11054195_2	909943.HIMB100_00022730	2.677e-50	192.0	COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,2VEQZ@28211|Alphaproteobacteria,4BQPH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
WLSH2_k127_11054195_0	257310.BB3815	1.075e-160	516.0	COG0477@1|root,COG2814@2|Bacteria,1QW9T@1224|Proteobacteria,2W1Q9@28216|Betaproteobacteria,3T5SY@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_11130466_4	566466.NOR53_1902	4.089e-05	48.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,1S6B1@1236|Gammaproteobacteria,1J94A@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
WLSH2_k127_11130466_2	266264.Rmet_1906	4.467e-59	217.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_11130466_0	572547.Amico_1296	4.636e-133	437.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WLSH2_k127_11130466_3	1003200.AXXA_23470	1.128e-42	162.0	COG1787@1|root,COG1787@2|Bacteria,1RGGQ@1224|Proteobacteria,2VTJ4@28216|Betaproteobacteria,3T67P@506|Alcaligenaceae	28216|Betaproteobacteria	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
WLSH2_k127_11130466_1	1082933.MEA186_13018	6.481e-86	291.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,2TUVZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2	rutB	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
WLSH2_k127_111405_4	522306.CAP2UW1_1932	1.53e-20	93.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria	1224|Proteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4,PGAP1
WLSH2_k127_111405_2	1000565.METUNv1_00885	2.511e-110	369.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria	28216|Betaproteobacteria	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
WLSH2_k127_111405_3	1159870.KB907784_gene1924	3.082e-95	315.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria,3T2J4@506|Alcaligenaceae	28216|Betaproteobacteria	S	Phospholipid-binding protein	ybhB	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
WLSH2_k127_111405_1	118163.Ple7327_0401	6.575e-136	444.0	COG1812@1|root,COG1812@2|Bacteria	2|Bacteria	E	S-adenosylmethionine synthetase (AdoMet synthetase)	metK-2	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_Synthase
WLSH2_k127_111405_0	1266925.JHVX01000001_gene2612	4.562e-283	902.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,3727F@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
WLSH2_k127_11152696_1	1266925.JHVX01000017_gene8	4.353e-48	173.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,373DG@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
WLSH2_k127_11152696_3	1201288.M900_0751	2.66e-12	76.0	COG0727@1|root,COG0727@2|Bacteria,1PCRF@1224|Proteobacteria,42XX7@68525|delta/epsilon subdivisions,2MUJJ@213481|Bdellovibrionales,2WY0N@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
WLSH2_k127_11152696_0	305700.B447_17119	5.844e-88	298.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,2KW1H@206389|Rhodocyclales	206389|Rhodocyclales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
WLSH2_k127_11152696_2	1304883.KI912532_gene1312	2.345e-26	108.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,2KV7M@206389|Rhodocyclales	206389|Rhodocyclales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH2_k127_11226471_10	257313.BP0148	2.997e-05	47.0	COG3181@1|root,COG3181@2|Bacteria,1NTXQ@1224|Proteobacteria,2W19N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_11226471_0	1125973.JNLC01000010_gene1417	1.33e-231	730.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,3JZ96@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WLSH2_k127_11226471_5	1125973.JNLC01000010_gene1416	7.053e-72	255.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3JVJ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	MA20_17650	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_11226471_6	101510.RHA1_ro11181	4.445e-64	230.0	COG0447@1|root,COG0447@2|Bacteria,2HGHM@201174|Actinobacteria,4FZY1@85025|Nocardiaceae	201174|Actinobacteria	H	Enoyl-CoA hydratase/isomerase	-	-	4.1.3.36	ko:K01661,ko:K07536	ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220	M00116,M00540	R05592,R07263	RC01429,RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH2_k127_11226471_3	1382356.JQMP01000001_gene1074	5.03e-136	444.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,27YZQ@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WLSH2_k127_11226471_9	1040986.ATYO01000024_gene3272	1.726e-34	137.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,2U728@28211|Alphaproteobacteria,43JXJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	methylmalonyl-CoA epimerase	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
WLSH2_k127_11226471_2	1298867.AUES01000089_gene2973	1.904e-147	474.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,3K2G8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
WLSH2_k127_11226471_1	1265502.KB905960_gene289	6.372e-152	490.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VHQF@28216|Betaproteobacteria,4ACST@80864|Comamonadaceae	28216|Betaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_11226471_8	12957.ACEP23121-PA	5.437e-51	194.0	COG0179@1|root,KOG1535@2759|Eukaryota,38DXI@33154|Opisthokonta,3BCS8@33208|Metazoa,3CYTW@33213|Bilateria,41V17@6656|Arthropoda,3SITR@50557|Insecta,46EYX@7399|Hymenoptera	33208|Metazoa	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
WLSH2_k127_11226471_7	1163617.SCD_n00578	1.711e-51	188.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	toluene tolerance family protein	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
WLSH2_k127_11226471_4	1123368.AUIS01000005_gene447	1.339e-104	355.0	COG0642@1|root,COG2205@2|Bacteria,1N58A@1224|Proteobacteria,1RP34@1236|Gammaproteobacteria,2NBSM@225057|Acidithiobacillales	225057|Acidithiobacillales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WLSH2_k127_11257592_0	765913.ThidrDRAFT_0188	1.078e-99	335.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1WWUA@135613|Chromatiales	135613|Chromatiales	M	Lytic murein transglycosylase B	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
WLSH2_k127_11257592_1	1255043.TVNIR_2201	3.081e-57	207.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1WW9X@135613|Chromatiales	135613|Chromatiales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
WLSH2_k127_11303135_7	1198452.Jab_2c19550	8.355e-29	119.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,472YF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
WLSH2_k127_11303135_1	1163617.SCD_n01808	1.959e-183	584.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria	28216|Betaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WLSH2_k127_11303135_0	1095769.CAHF01000011_gene2398	4.216e-195	616.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,472E5@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
WLSH2_k127_11303135_6	640081.Dsui_3143	9.649e-42	164.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,2KWMY@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
WLSH2_k127_11303135_5	1163617.SCD_n01811	1.096e-67	241.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
WLSH2_k127_11303135_3	279714.FuraDRAFT_3051	9.718e-154	493.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,2KPVD@206351|Neisseriales	206351|Neisseriales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
WLSH2_k127_11303135_4	580332.Slit_1410	4.204e-72	244.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,44VQP@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WLSH2_k127_11303135_2	1411123.JQNH01000001_gene3100	1.894e-179	576.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	transport system fused permease components	-	-	-	-	-	-	-	-	-	-	-	-	DctM
WLSH2_k127_11348510_2	580332.Slit_0040	1.202e-58	215.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,44VTH@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
WLSH2_k127_11348510_0	580332.Slit_0041	7.001e-138	443.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,44V55@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
WLSH2_k127_11348510_3	153948.NAL212_0552	1.327e-29	118.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,373M4@32003|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
WLSH2_k127_11348510_1	1472716.KBK24_0124995	5.999e-63	219.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,1K6XN@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Lactoylglutathione lyase	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
WLSH2_k127_11348510_4	1123399.AQVE01000003_gene2076	5.658e-12	66.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,460FK@72273|Thiotrichales	72273|Thiotrichales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WLSH2_k127_11402405_5	1205910.B005_3997	1.241e-51	186.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4EIS8@85012|Streptosporangiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WLSH2_k127_11402405_6	864073.HFRIS_000685	1.008e-23	115.0	COG1073@1|root,COG1073@2|Bacteria,1PJHS@1224|Proteobacteria,2VXXE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0255 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1100
WLSH2_k127_11402405_2	596154.Alide2_3931	1.167e-75	269.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_11402405_0	1123072.AUDH01000002_gene2408	1.223e-82	286.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JSUV@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_11402405_1	1268622.AVS7_03447	6.223e-80	278.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_11402405_4	1173024.KI912153_gene41	1.625e-57	212.0	COG0583@1|root,COG0583@2|Bacteria,1G4IM@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WLSH2_k127_11402405_3	1123023.JIAI01000004_gene7902	6.675e-60	220.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WLSH2_k127_11402405_7	742733.HMPREF9469_04197	9.863e-15	81.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia,21ZKU@1506553|Lachnoclostridium	186801|Clostridia	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
WLSH2_k127_11405859_7	1122604.JONR01000014_gene218	7.231e-45	171.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WLSH2_k127_11405859_6	1122604.JONR01000045_gene2493	2.344e-62	226.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,1T055@1236|Gammaproteobacteria,1X6SQ@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_11405859_8	1122604.JONR01000035_gene348	1.543e-43	166.0	2CDFS@1|root,32RXQ@2|Bacteria,1N09V@1224|Proteobacteria,1S47Q@1236|Gammaproteobacteria,1X6G8@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF2946)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2944
WLSH2_k127_11405859_4	1216976.AX27061_0018	7.052e-100	336.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VN62@28216|Betaproteobacteria,3T73S@506|Alcaligenaceae	28216|Betaproteobacteria	E	Threonine aldolase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WLSH2_k127_11405859_9	580332.Slit_1703	5.693e-37	145.0	COG3439@1|root,COG3439@2|Bacteria,1RHPD@1224|Proteobacteria,2VV5X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WLSH2_k127_11405859_13	1538295.JY96_03805	6.764e-05	51.0	2ANGV@1|root,31DFK@2|Bacteria,1RJ5C@1224|Proteobacteria,2VSDR@28216|Betaproteobacteria,1KM8N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	hctB	-	-	ko:K11275	-	-	-	-	ko00000,ko03036	-	-	-	HC2
WLSH2_k127_11405859_12	1449080.JQMV01000002_gene45	3.158e-06	55.0	2EH09@1|root,33ASB@2|Bacteria,1WKPC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
WLSH2_k127_11405859_1	1000565.METUNv1_00215	2.89e-209	653.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,2KUGC@206389|Rhodocyclales	206389|Rhodocyclales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
WLSH2_k127_11405859_0	93220.LV28_11250	0.0	1404.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,1K1JU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
WLSH2_k127_11405859_5	1266925.JHVX01000009_gene44	9.731e-77	260.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,3731N@32003|Nitrosomonadales	28216|Betaproteobacteria	V	N-acetylmuramoyl-L-alanine amidase (Family 2)	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
WLSH2_k127_11405859_2	870187.Thini_1703	1.41e-140	460.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,45ZTS@72273|Thiotrichales	72273|Thiotrichales	T	PFAM response regulator receiver	-	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH2_k127_11405859_3	261292.Nit79A3_2376	7.747e-131	435.0	COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,2WGR4@28216|Betaproteobacteria,372VJ@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
WLSH2_k127_11405859_10	1223521.BBJX01000016_gene682	7.71e-14	76.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	Metallothio_Pro
WLSH2_k127_11405859_11	1437824.BN940_02181	3.718e-07	58.0	COG2128@1|root,COG2128@2|Bacteria,1MVWP@1224|Proteobacteria,2VS89@28216|Betaproteobacteria,3T3PQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Alkylhydroperoxidase AhpD family core domain-containing protein 7	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WLSH2_k127_11419553_3	1121439.dsat_1861	3.666e-05	47.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2MBU6@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WLSH2_k127_11419553_1	1288494.EBAPG3_28000	9.957e-64	222.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,3733Q@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
WLSH2_k127_11419553_0	1163617.SCD_n00210	1.987e-160	509.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH2_k127_11419553_2	267608.RSc0679	6.391e-58	202.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,1K38Y@119060|Burkholderiaceae	28216|Betaproteobacteria	F	dihydroorotase multifunctional complex type	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WLSH2_k127_11438184_1	375286.mma_0819	9.644e-81	277.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2VNS2@28216|Betaproteobacteria,476I4@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
WLSH2_k127_11438184_0	1380394.JADL01000001_gene1950	3.616e-127	424.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2TSQ3@28211|Alphaproteobacteria,2JR8N@204441|Rhodospirillales	204441|Rhodospirillales	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
WLSH2_k127_11438184_2	375286.mma_0820	4.83e-64	222.0	COG1917@1|root,COG1917@2|Bacteria,1MYMN@1224|Proteobacteria	1224|Proteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_11438184_3	1205680.CAKO01000006_gene3271	2.686e-49	183.0	COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
WLSH2_k127_11450547_2	247490.KSU1_D0588	1.198e-11	65.0	COG3431@1|root,COG3431@2|Bacteria,2J3HB@203682|Planctomycetes	203682|Planctomycetes	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
WLSH2_k127_11450547_0	1163617.SCD_n01708	3.713e-94	315.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WLSH2_k127_11450547_1	1288494.EBAPG3_10830	1.214e-20	92.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,372ZQ@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WLSH2_k127_1150893_8	1288494.EBAPG3_7520	3.989e-06	49.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,371XY@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH2_k127_1150893_3	1231190.NA8A_23247	1.697e-81	282.0	COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	MA20_20400	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
WLSH2_k127_1150893_6	1267005.KB911265_gene3648	2.78e-13	81.0	COG0664@1|root,COG0664@2|Bacteria,1N6WV@1224|Proteobacteria	1224|Proteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WLSH2_k127_1150893_7	41431.PCC8801_2732	2.983e-10	71.0	COG0428@1|root,COG0664@1|root,COG0428@2|Bacteria,COG0664@2|Bacteria,1G2YK@1117|Cyanobacteria,3KHKG@43988|Cyanothece	1117|Cyanobacteria	PT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Zip,cNMP_binding
WLSH2_k127_1150893_1	1163617.SCD_n01896	2.114e-153	496.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WLSH2_k127_1150893_0	887898.HMPREF0551_2591	7.725e-201	645.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,1K219@119060|Burkholderiaceae	28216|Betaproteobacteria	S	abc transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH2_k127_1150893_4	153948.NAL212_0904	4.014e-80	272.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,372XK@32003|Nitrosomonadales	28216|Betaproteobacteria	U	MotA TolQ ExbB proton channel	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
WLSH2_k127_1150893_5	1163617.SCD_n01894	1.158e-43	163.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WLSH2_k127_1150893_2	1485544.JQKP01000001_gene1259	1.296e-98	331.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,44UYT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
WLSH2_k127_1189487_0	667632.KB890165_gene2485	1.1e-102	350.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1K035@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_1189487_2	232721.Ajs_3546	8.396e-67	239.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_1189487_3	870187.Thini_2219	3.26e-61	220.0	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,1S8DJ@1236|Gammaproteobacteria,463PP@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
WLSH2_k127_1189487_1	543728.Vapar_0801	2.32e-76	267.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJCY@28216|Betaproteobacteria,4ABM4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_1189487_4	1131730.BAVI_13164	4.353e-56	210.0	COG2159@1|root,COG2159@2|Bacteria,1UXYD@1239|Firmicutes,4HDAD@91061|Bacilli,1ZDX2@1386|Bacillus	91061|Bacilli	S	Amidohydrolase	-	-	4.1.1.45,4.1.1.52	ko:K03392,ko:K22213	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
WLSH2_k127_1189487_5	292414.TM1040_1594	2.92e-05	51.0	COG0329@1|root,COG0329@2|Bacteria,1R73B@1224|Proteobacteria,2U0S8@28211|Alphaproteobacteria,4N9ZS@97050|Ruegeria	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WLSH2_k127_1303468_4	265072.Mfla_2518	2.122e-09	60.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,2KKXA@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Neisseria PilC beta-propeller domain	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
WLSH2_k127_1303468_3	522306.CAP2UW1_2244	1.182e-11	73.0	COG0810@1|root,COG0810@2|Bacteria,1NATT@1224|Proteobacteria	1224|Proteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WLSH2_k127_1303468_1	1123392.AQWL01000001_gene1572	1.013e-149	479.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,1KRES@119069|Hydrogenophilales	119069|Hydrogenophilales	IM	LytB protein	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
WLSH2_k127_1303468_2	1097668.BYI23_A005420	4.506e-52	189.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,1K1IQ@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WLSH2_k127_1303468_0	93220.LV28_08895	1.635e-219	691.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,1K19S@119060|Burkholderiaceae	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WLSH2_k127_1304298_1	1288494.EBAPG3_27800	1.327e-120	399.0	COG0705@1|root,COG0705@2|Bacteria,1PRTS@1224|Proteobacteria,2VM82@28216|Betaproteobacteria,372KP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Lactonase,Rhomboid
WLSH2_k127_1304298_2	1163617.SCD_n00202	2.497e-31	131.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Pfam Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
WLSH2_k127_1304298_0	1163617.SCD_n00204	1.33e-322	999.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
WLSH2_k127_1344915_3	87626.PTD2_18870	3.585e-57	203.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q0X3@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	V	COG0841 Cation multidrug efflux pump	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
WLSH2_k127_1344915_0	1485544.JQKP01000008_gene1754	1.089e-111	379.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,44VTV@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	oprM	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
WLSH2_k127_1344915_2	1392838.AWNM01000097_gene173	9.932e-70	251.0	COG3181@1|root,COG3181@2|Bacteria,1NSUZ@1224|Proteobacteria,2W1MS@28216|Betaproteobacteria,3T6Q1@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_1344915_7	349521.HCH_04873	6.671e-18	90.0	COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,1SFI3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WLSH2_k127_1344915_5	266264.Rmet_5781	4.842e-56	206.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1344915_4	1121127.JAFA01000017_gene6233	5.79e-57	208.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2W0Q1@28216|Betaproteobacteria,1K5B3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WLSH2_k127_1344915_1	1163617.SCD_n02327	1.281e-70	244.0	COG0778@1|root,COG0778@2|Bacteria,1RA6E@1224|Proteobacteria,2VSIM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pfam Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_1344915_6	1123269.NX02_25690	4.541e-29	120.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2TSHC@28211|Alphaproteobacteria,2K0UX@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WLSH2_k127_148082_1	1123487.KB892863_gene1916	3.794e-20	93.0	COG0300@1|root,COG0300@2|Bacteria,1RAFB@1224|Proteobacteria,2VS3H@28216|Betaproteobacteria,2KWFE@206389|Rhodocyclales	206389|Rhodocyclales	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_148082_0	1123261.AXDW01000019_gene691	7.904e-151	498.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RNJ3@1236|Gammaproteobacteria,1X4IG@135614|Xanthomonadales	135614|Xanthomonadales	M	COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
WLSH2_k127_1501344_6	580332.Slit_2120	1.599e-38	156.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,44VR7@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
WLSH2_k127_1501344_3	640081.Dsui_3194	6.352e-103	342.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,2KU8S@206389|Rhodocyclales	206389|Rhodocyclales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WLSH2_k127_1501344_5	1163617.SCD_n00880	8.271e-78	266.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
WLSH2_k127_1501344_0	159087.Daro_0870	8.956e-224	697.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,2KUYW@206389|Rhodocyclales	206389|Rhodocyclales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH2_k127_1501344_2	1198452.Jab_2c21690	4.208e-107	354.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,4724H@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
WLSH2_k127_1501344_1	1288494.EBAPG3_25400	7.115e-140	449.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,37257@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH2_k127_1501344_4	1288494.EBAPG3_25390	8.636e-93	311.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,371U0@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH2_k127_1559587_6	760117.JN27_14305	1.962e-39	155.0	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,2VWWI@28216|Betaproteobacteria,475RE@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WLSH2_k127_1559587_0	1288494.EBAPG3_6760	1.5e-323	1006.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,372D7@32003|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH2_k127_1559587_7	279714.FuraDRAFT_1296	3.371e-08	58.0	28WUG@1|root,2ZITX@2|Bacteria,1P7A0@1224|Proteobacteria,2W6CM@28216|Betaproteobacteria,2KTNV@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1559587_4	1304883.KI912532_gene2952	1.193e-66	234.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,2KWH0@206389|Rhodocyclales	206389|Rhodocyclales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
WLSH2_k127_1559587_1	1266925.JHVX01000023_gene2426	2.634e-195	617.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,372TB@32003|Nitrosomonadales	28216|Betaproteobacteria	L	AAA C-terminal domain	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
WLSH2_k127_1559587_5	748247.AZKH_0179	6.464e-44	166.0	COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,2VTWU@28216|Betaproteobacteria,2KXW7@206389|Rhodocyclales	206389|Rhodocyclales	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_1559587_3	1207063.P24_13693	6.478e-80	277.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,2JS33@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WLSH2_k127_1559587_2	396588.Tgr7_1189	1.782e-167	535.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1WX7U@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WLSH2_k127_156837_3	1288494.EBAPG3_1440	3.013e-90	297.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,371QW@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
WLSH2_k127_156837_1	614083.AWQR01000055_gene1969	1.2e-122	410.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,4A9MA@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
WLSH2_k127_156837_2	795666.MW7_0759	5.578e-98	326.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VIKP@28216|Betaproteobacteria,1K47S@119060|Burkholderiaceae	28216|Betaproteobacteria	V	abc transporter	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
WLSH2_k127_156837_0	795666.MW7_0760	8.924e-163	525.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria	28216|Betaproteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_156837_4	1454004.AW11_00123	1.484e-54	196.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,1KQCR@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WLSH2_k127_1628691_1	626418.bglu_1g06430	1.903e-144	464.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1K2VU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WLSH2_k127_1628691_3	1163617.SCD_n02352	8.905e-50	184.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the DnaA family	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
WLSH2_k127_1628691_2	1485544.JQKP01000019_gene9	4.802e-100	330.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,44VMB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
WLSH2_k127_1628691_0	1163617.SCD_n02221	5.597e-177	562.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
WLSH2_k127_1674505_0	396588.Tgr7_2455	7.889e-130	422.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WLSH2_k127_1674505_1	1163617.SCD_n00058	3.294e-67	235.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH2_k127_1674505_3	323848.Nmul_A0361	4.873e-39	149.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,373F4@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WLSH2_k127_1674505_2	395019.Bmul_0979	2.859e-51	186.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,1K1UB@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WLSH2_k127_1674505_4	1502852.FG94_04252	5.643e-23	100.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,4730D@75682|Oxalobacteraceae	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WLSH2_k127_1725111_11	3988.XP_002537284.1	9.953e-05	48.0	COG0637@1|root,KOG2914@2759|Eukaryota	2759|Eukaryota	L	pseudouridine 5'-phosphatase activity	-	-	2.7.1.26,3.1.3.102	ko:K03456,ko:K20884	ko00740,ko01100,ko01110,ko03015,ko04071,ko04111,ko04113,ko04114,ko04151,ko04152,ko04261,ko04350,ko04390,ko04391,ko04530,ko04728,ko04730,ko05142,ko05160,ko05165,map00740,map01100,map01110,map03015,map04071,map04111,map04113,map04114,map04151,map04152,map04261,map04350,map04390,map04391,map04530,map04728,map04730,map05142,map05160,map05165	M00125	R00548,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03036	-	-	-	HAD_2,NTP_transf_3
WLSH2_k127_1725111_7	1288494.EBAPG3_24390	2.033e-112	367.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,372PR@32003|Nitrosomonadales	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
WLSH2_k127_1725111_3	640081.Dsui_1936	7.758e-174	564.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,2KV5W@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WLSH2_k127_1725111_9	1095769.CAHF01000013_gene3280	7.384e-31	132.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,4727Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Belongs to the ompA family	ompA	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
WLSH2_k127_1725111_0	1288494.EBAPG3_24420	0.0	1314.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,3720I@32003|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH2_k127_1725111_4	472759.Nhal_2629	1.309e-161	516.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WLSH2_k127_1725111_2	292415.Tbd_0950	2.9e-181	576.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_1725111_6	580332.Slit_2065	5.096e-122	406.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,44UYW@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Chorismate mutase type II	pheA	-	4.2.1.51,4.2.1.91,5.4.99.5	ko:K01713,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
WLSH2_k127_1725111_5	85643.Tmz1t_3038	1.088e-155	499.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,2KV2R@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC1	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_1725111_8	1163617.SCD_n01031	4.676e-91	311.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
WLSH2_k127_1725111_1	62928.azo1071	3.04e-187	594.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,2KUWK@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	cmk	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
WLSH2_k127_1725111_10	1266925.JHVX01000006_gene2097	9.395e-15	75.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2VQ2F@28216|Betaproteobacteria,372WR@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WLSH2_k127_1767037_2	1288494.EBAPG3_11670	3.866e-161	515.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,37261@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WLSH2_k127_1767037_0	640081.Dsui_0891	5.586e-275	858.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,2KUYH@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WLSH2_k127_1767037_4	1163617.SCD_n00099	4.399e-42	169.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
WLSH2_k127_1767037_3	1562701.BBOF01000061_gene1725	1.568e-82	283.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,1K372@119060|Burkholderiaceae	28216|Betaproteobacteria	M	shape-determining protein MreC	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WLSH2_k127_1767037_1	640081.Dsui_0888	2.189e-192	604.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,2KUHG@206389|Rhodocyclales	206389|Rhodocyclales	D	Rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WLSH2_k127_1767037_5	323848.Nmul_A0321	9.536e-35	136.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,373HB@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WLSH2_k127_1767037_6	1163617.SCD_n00095	6.736e-06	51.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH2_k127_1855657_10	666684.AfiDRAFT_2860	2.022e-105	352.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,3K3CR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_1855657_2	1532557.JL37_13495	1.223e-173	552.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VHBI@28216|Betaproteobacteria,3T36A@506|Alcaligenaceae	28216|Betaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_1855657_6	1121861.KB899926_gene2599	3.795e-138	451.0	COG0477@1|root,COG2814@2|Bacteria,1P3S4@1224|Proteobacteria,2TVAQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_1855657_11	1411123.JQNH01000001_gene2071	1.03e-99	332.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.1.1.41,4.2.1.17	ko:K01692,ko:K11264	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH2_k127_1855657_1	883080.HMPREF9697_01684	2.237e-187	598.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria,3JUBU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	MA20_34330	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WLSH2_k127_1855657_3	95619.PM1_0222010	1.966e-164	526.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed	dcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH2_k127_1855657_16	76114.ebA5423	5.436e-43	164.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,2KWJN@206389|Rhodocyclales	206389|Rhodocyclales	S	ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
WLSH2_k127_1855657_8	1132855.KB913035_gene1461	5.105e-114	376.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,2KKZF@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WLSH2_k127_1855657_14	1163617.SCD_n01526	5.848e-78	272.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria	28216|Betaproteobacteria	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WLSH2_k127_1855657_15	266264.Rmet_1828	2.521e-72	249.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,1JZWI@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WLSH2_k127_1855657_9	1266925.JHVX01000004_gene1104	1.88e-113	376.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,372WQ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WLSH2_k127_1855657_13	1163617.SCD_n01529	4.741e-79	272.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2VRAS@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	PFAM Aminotransferase, class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
WLSH2_k127_1855657_0	1163617.SCD_n01531	2.173e-206	649.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria	28216|Betaproteobacteria	I	catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH2_k127_1855657_17	1286093.C266_07407	1.964e-35	135.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,1K979@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH2_k127_1855657_12	1163617.SCD_n01533	2.375e-99	330.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	reductase	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_1855657_7	388051.AUFE01000010_gene2555	6.387e-133	430.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1K35C@119060|Burkholderiaceae	28216|Betaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WLSH2_k127_1855657_5	335283.Neut_0470	9.259e-146	468.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,371X7@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WLSH2_k127_1855657_4	1163617.SCD_n01536	2.566e-158	505.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WLSH2_k127_1855657_18	1379698.RBG1_1C00001G1778	2.637e-13	77.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
WLSH2_k127_1906768_1	1266925.JHVX01000006_gene2240	1.78e-104	347.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,372X1@32003|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	yajR	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_1906768_0	261292.Nit79A3_3174	0.0	1470.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,3726S@32003|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH2_k127_193383_1	977880.RALTA_A0643	2.766e-21	102.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria,1K15Q@119060|Burkholderiaceae	28216|Betaproteobacteria	T	CBS domain containing protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
WLSH2_k127_193383_0	1123368.AUIS01000003_gene1810	2.344e-94	321.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	CBS-domain-containing membrane protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	HPP
WLSH2_k127_193637_1	1163617.SCD_n02358	6.431e-43	166.0	COG3170@1|root,COG3170@2|Bacteria,1N3SZ@1224|Proteobacteria,2VU3V@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
WLSH2_k127_193637_0	1121035.AUCH01000002_gene1481	2.706e-79	274.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,2KVYQ@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
WLSH2_k127_193637_2	977880.RALTA_A2552	2.038e-32	127.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,1K2VU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WLSH2_k127_1952535_2	580332.Slit_1839	3.904e-216	678.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,44V9G@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WLSH2_k127_1952535_3	279714.FuraDRAFT_1119	7.098e-133	425.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,2KQ3X@206351|Neisseriales	206351|Neisseriales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17
WLSH2_k127_1952535_5	1249627.D779_3513	1.493e-12	70.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1WZ6Q@135613|Chromatiales	135613|Chromatiales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
WLSH2_k127_1952535_1	883126.HMPREF9710_02063	1.723e-219	687.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,472V7@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WLSH2_k127_1952535_0	1288494.EBAPG3_15680	0.0	1245.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,371W3@32003|Nitrosomonadales	28216|Betaproteobacteria	C	dehydrogenase, E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
WLSH2_k127_1952535_4	1288494.EBAPG3_15670	2.503e-18	85.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,372IF@32003|Nitrosomonadales	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WLSH2_k127_201485_12	292415.Tbd_2149	1.429e-40	154.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,2WEFV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	Lipase_GDSL_2
WLSH2_k127_201485_0	1198452.Jab_1c12150	1.064e-228	721.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2VRSD@28216|Betaproteobacteria,475NM@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,DAO,NAD_binding_8
WLSH2_k127_201485_8	94624.Bpet0369	2.694e-58	227.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,3T2GI@506|Alcaligenaceae	28216|Betaproteobacteria	C	COG3245 Cytochrome c5	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WLSH2_k127_201485_4	580332.Slit_2871	3.508e-109	359.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,44VCX@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
WLSH2_k127_201485_6	1163617.SCD_n02773	6.628e-63	231.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH2_k127_201485_5	159087.Daro_3934	1.837e-95	319.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,2KU7J@206389|Rhodocyclales	206389|Rhodocyclales	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
WLSH2_k127_201485_11	1348657.M622_03845	5.835e-47	173.0	COG3133@1|root,COG3133@2|Bacteria,1RJWY@1224|Proteobacteria,2WE8P@28216|Betaproteobacteria,2KWZB@206389|Rhodocyclales	206389|Rhodocyclales	M	17 kDa surface antigen	slyB	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
WLSH2_k127_201485_1	1163617.SCD_n02776	3.045e-157	500.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM PfkB domain protein	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WLSH2_k127_201485_7	1120999.JONM01000008_gene1989	1.939e-61	215.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,2KRC6@206351|Neisseriales	206351|Neisseriales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WLSH2_k127_201485_9	582744.Msip34_1870	6.163e-53	192.0	COG0671@1|root,COG0671@2|Bacteria,1RHGF@1224|Proteobacteria,2WEWF@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WLSH2_k127_201485_2	1123392.AQWL01000002_gene1924	4.737e-146	477.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2VJ5X@28216|Betaproteobacteria,1KRAX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
WLSH2_k127_201485_10	1121035.AUCH01000002_gene1549	2.777e-49	179.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
WLSH2_k127_201485_3	1163617.SCD_n02778	7.758e-124	400.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
WLSH2_k127_2015440_1	76114.ebA4343	3.534e-102	336.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,2KVU7@206389|Rhodocyclales	206389|Rhodocyclales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WLSH2_k127_2015440_3	497321.C664_19426	1.383e-63	224.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KW4Z@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WLSH2_k127_2015440_2	1163617.SCD_n02469	3.932e-101	336.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
WLSH2_k127_2015440_4	795666.MW7_3115	9.283e-21	93.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,1KA41@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
WLSH2_k127_2015440_0	1163617.SCD_n02471	3.48e-107	356.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
WLSH2_k127_2097704_1	1349767.GJA_3912	1.244e-08	55.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,2VSCI@28216|Betaproteobacteria,474K8@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
WLSH2_k127_2097704_0	1116472.MGMO_50c00240	2.236e-117	394.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,1XG98@135618|Methylococcales	135618|Methylococcales	H	Pyruvate kinase, alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	PK,PK_C
WLSH2_k127_2121411_0	1163617.SCD_n02069	1.455e-145	473.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WLSH2_k127_2121411_4	870187.Thini_2788	1.81e-28	119.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,4615Y@72273|Thiotrichales	72273|Thiotrichales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WLSH2_k127_2121411_3	1288494.EBAPG3_28670	7.016e-40	153.0	COG0735@1|root,COG0735@2|Bacteria,1NPTK@1224|Proteobacteria,2VSCH@28216|Betaproteobacteria,373AU@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WLSH2_k127_2121411_1	414684.RC1_2905	1.131e-63	224.0	COG1136@1|root,COG1136@2|Bacteria,1QU8Q@1224|Proteobacteria,2TWD6@28211|Alphaproteobacteria,2JYYE@204441|Rhodospirillales	204441|Rhodospirillales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_2121411_2	1239962.C943_02534	8.729e-47	177.0	COG0577@1|root,COG0577@2|Bacteria,4NF60@976|Bacteroidetes,47KE0@768503|Cytophagia	976|Bacteroidetes	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_2175699_1	323848.Nmul_A1128	8.346e-57	204.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,3732H@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphoribosyl transferase domain	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WLSH2_k127_2175699_0	296591.Bpro_0610	9.747e-171	552.0	COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,2VIR3@28216|Betaproteobacteria,4AD84@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Outer membrane usher protein	-	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	PapC_C,Usher
WLSH2_k127_2194283_3	1485544.JQKP01000002_gene1427	4.135e-134	432.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,44VG9@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
WLSH2_k127_2194283_4	76114.ebA3579	1.854e-101	338.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,2KVIE@206389|Rhodocyclales	206389|Rhodocyclales	V	ABC-2 type transporter	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
WLSH2_k127_2194283_8	264198.Reut_A2830	2.63e-62	216.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,1K6Z5@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
WLSH2_k127_2194283_10	1123392.AQWL01000008_gene1215	2.844e-36	147.0	2DMN0@1|root,32SKB@2|Bacteria,1N2XU@1224|Proteobacteria,2VUWF@28216|Betaproteobacteria,1KTFG@119069|Hydrogenophilales	119069|Hydrogenophilales	S	HIRAN domain	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
WLSH2_k127_2194283_2	557598.LHK_02782	1.648e-142	462.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,2KPDK@206351|Neisseriales	206351|Neisseriales	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
WLSH2_k127_2194283_7	1286631.X805_10810	4.01e-72	244.0	COG4337@1|root,COG4337@2|Bacteria,1RD42@1224|Proteobacteria,2VRTA@28216|Betaproteobacteria,1KNH4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2194283_12	1121904.ARBP01000003_gene6362	7.798e-24	107.0	29C7G@1|root,2ZZ61@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2194283_9	1120956.JHZK01000002_gene951	3.144e-53	192.0	COG3153@1|root,COG3153@2|Bacteria,1RHPP@1224|Proteobacteria,2VCQG@28211|Alphaproteobacteria,1JQ92@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WLSH2_k127_2194283_11	266264.Rmet_1940	5.893e-33	138.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria,1K70I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WLSH2_k127_2194283_0	640081.Dsui_0605	4.174e-203	637.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KU9J@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH2_k127_2194283_1	640081.Dsui_0604	7.952e-198	619.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,2KVBG@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH2_k127_2194283_5	272560.BPSL2846	1.573e-83	284.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1JZTS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WLSH2_k127_2194283_6	1485544.JQKP01000002_gene1638	1.796e-74	258.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,44V7F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
WLSH2_k127_2224264_0	1163617.SCD_n00855	0.0	1007.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
WLSH2_k127_2224264_3	1125863.JAFN01000001_gene3237	7.044e-107	354.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,42QPM@68525|delta/epsilon subdivisions,2WMRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1716	ECH_1
WLSH2_k127_2224264_1	1123367.C666_09300	7.227e-252	789.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,2KV59@206389|Rhodocyclales	206389|Rhodocyclales	I	poly(R)-hydroxyalkanoic acid synthase	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,PhaC_N
WLSH2_k127_2224264_7	1268237.G114_17886	4.478e-33	132.0	COG0789@1|root,COG0789@2|Bacteria,1RITY@1224|Proteobacteria,1S61S@1236|Gammaproteobacteria,1Y5V7@135624|Aeromonadales	135624|Aeromonadales	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
WLSH2_k127_2224264_4	1454004.AW11_03897	5.484e-72	249.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2VQJ1@28216|Betaproteobacteria,1KQTA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	5.99.1.4	ko:K14584	ko00626,ko01100,ko01120,ko01220,map00626,map01100,map01120,map01220	M00534	R05137	RC03084	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DSBA
WLSH2_k127_2224264_5	269799.Gmet_3291	1.22e-69	246.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,42S4C@68525|delta/epsilon subdivisions,2WNXY@28221|Deltaproteobacteria,43T1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH2_k127_2224264_2	1528106.JRJE01000004_gene622	8.333e-122	402.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,2JPU7@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0119 Isopropylmalate homocitrate citramalate synthases	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
WLSH2_k127_2224264_8	522306.CAP2UW1_4324	1.143e-10	66.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2VXYJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
WLSH2_k127_2224264_6	1207063.P24_06846	5.566e-59	209.0	2BZNP@1|root,30717@2|Bacteria,1REWN@1224|Proteobacteria,2U7X0@28211|Alphaproteobacteria,2JSDR@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
WLSH2_k127_2224264_9	1232410.KI421427_gene1264	2.868e-05	47.0	COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,42R72@68525|delta/epsilon subdivisions,2WMSM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_2232966_2	1122134.KB893650_gene1358	1.083e-43	166.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1XICC@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
WLSH2_k127_2232966_1	94624.Bpet4723	1.363e-63	224.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,3T6CU@506|Alcaligenaceae	28216|Betaproteobacteria	S	Belongs to the LOG family	yvdD_1	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WLSH2_k127_2232966_0	580332.Slit_1711	5.059e-294	908.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44WAX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WLSH2_k127_2290215_4	1123073.KB899242_gene1461	2.966e-154	491.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,1RREP@1236|Gammaproteobacteria,1XA61@135614|Xanthomonadales	135614|Xanthomonadales	CE	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2
WLSH2_k127_2290215_0	522306.CAP2UW1_2583	6.905e-312	963.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
WLSH2_k127_2290215_2	1454004.AW11_01300	9.087e-185	582.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH2_k127_2290215_1	381666.H16_B0977	2.765e-280	873.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,1K1CB@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
WLSH2_k127_2290215_5	1207063.P24_01670	1.304e-77	267.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2TTDW@28211|Alphaproteobacteria,2JRVY@204441|Rhodospirillales	204441|Rhodospirillales	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
WLSH2_k127_2290215_8	1207063.P24_01675	4.887e-26	110.0	COG5501@1|root,COG5501@2|Bacteria,1N03V@1224|Proteobacteria,2TWQY@28211|Alphaproteobacteria,2JUCR@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulphur oxidation protein SoxZ	-	-	-	-	-	-	-	-	-	-	-	-	SoxZ
WLSH2_k127_2290215_7	113395.AXAI01000014_gene177	1.726e-34	137.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2U72E@28211|Alphaproteobacteria,3JUV9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Sulfur oxidation protein SoxY	MA20_17510	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
WLSH2_k127_2290215_6	1245469.S58_51900	5.779e-42	158.0	COG2010@1|root,COG2010@2|Bacteria,1RIV2@1224|Proteobacteria,2U9C5@28211|Alphaproteobacteria,3JZ5J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
WLSH2_k127_2290215_3	1411123.JQNH01000001_gene3657	3.442e-169	542.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	MA20_17495	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
WLSH2_k127_2360638_4	1392838.AWNM01000096_gene3108	2.435e-13	72.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2360638_1	1380394.JADL01000001_gene2943	2.61e-115	380.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2V9T4@28211|Alphaproteobacteria,2JVCK@204441|Rhodospirillales	204441|Rhodospirillales	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
WLSH2_k127_2360638_3	330214.NIDE2523	4.647e-67	253.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE2523|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2360638_2	1380394.JADL01000001_gene2932	2.995e-110	364.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TUUN@28211|Alphaproteobacteria,2JWV8@204441|Rhodospirillales	204441|Rhodospirillales	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
WLSH2_k127_2360638_0	1380394.JADL01000001_gene2941	6.333e-136	440.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TT8I@28211|Alphaproteobacteria,2JV7M@204441|Rhodospirillales	204441|Rhodospirillales	E	Aconitase family (aconitate hydratase)	-	-	-	-	-	-	-	-	-	-	-	-	Aconitase
WLSH2_k127_2425984_5	1095769.CAHF01000013_gene3255	1.303e-91	307.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,2VHAG@28216|Betaproteobacteria,472E6@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
WLSH2_k127_2425984_7	614083.AWQR01000049_gene3200	5.405e-49	188.0	2B4TG@1|root,31XK1@2|Bacteria,1RIY8@1224|Proteobacteria,2VTMB@28216|Betaproteobacteria,4AF7U@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2425984_6	1037409.BJ6T_48040	2.202e-77	262.0	COG5553@1|root,COG5553@2|Bacteria,1NDMC@1224|Proteobacteria,2UKAN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2425984_4	864069.MicloDRAFT_00003630	2.759e-96	344.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,2TTSG@28211|Alphaproteobacteria,1JSNC@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WLSH2_k127_2425984_0	1207063.P24_02186	9.403e-129	425.0	COG0534@1|root,COG0534@2|Bacteria,1MV6B@1224|Proteobacteria,2TSKZ@28211|Alphaproteobacteria,2JPNM@204441|Rhodospirillales	204441|Rhodospirillales	V	COG0534 Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WLSH2_k127_2425984_2	296591.Bpro_4316	6.012e-107	356.0	COG3181@1|root,COG3181@2|Bacteria,1NBZ9@1224|Proteobacteria,2VH6P@28216|Betaproteobacteria,4ADAM@80864|Comamonadaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2425984_1	640512.BC1003_5360	2.753e-111	367.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2VIDM@28216|Betaproteobacteria,1K42J@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	3.1.1.57	ko:K10221	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R04277	RC03110	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
WLSH2_k127_2425984_3	1205680.CAKO01000010_gene3710	1.426e-102	342.0	COG2175@1|root,COG2175@2|Bacteria,1P6UZ@1224|Proteobacteria,2TTJB@28211|Alphaproteobacteria,2JYSV@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
WLSH2_k127_2425984_8	1205680.CAKO01000035_gene204	7.656e-32	133.0	COG1802@1|root,COG1802@2|Bacteria,1RHPF@1224|Proteobacteria,2UCZ2@28211|Alphaproteobacteria,2JX8Z@204441|Rhodospirillales	204441|Rhodospirillales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WLSH2_k127_2510567_3	1121861.KB899931_gene137	6.142e-05	47.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JSUV@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2510567_2	331869.BAL199_30197	3.976e-22	107.0	COG2520@1|root,COG2520@2|Bacteria,1QZ37@1224|Proteobacteria,2TY3P@28211|Alphaproteobacteria,4BTE7@82117|unclassified Alphaproteobacteria	2|Bacteria	J	2OG-Fe(II) oxygenase superfamily	-	-	2.1.1.228	ko:K15429	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltransf_31,rRNA_methylase
WLSH2_k127_2510567_1	395495.Lcho_0484	3.897e-74	258.0	COG2227@1|root,COG2520@1|root,COG2227@2|Bacteria,COG2520@2|Bacteria	2|Bacteria	J	tRNA (guanine(37)-N(1))-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25
WLSH2_k127_2510567_0	264198.Reut_B4564	8.559e-109	359.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2VKB0@28216|Betaproteobacteria,1K405@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WLSH2_k127_2534061_0	388051.AUFE01000033_gene3729	4.845e-77	271.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2534061_2	323848.Nmul_A2153	7.725e-11	64.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2VJV0@28216|Betaproteobacteria,3739T@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WLSH2_k127_2534061_1	1366050.N234_06345	1.462e-54	201.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,2VRAN@28216|Betaproteobacteria,1KH61@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
WLSH2_k127_2534061_4	547163.BN979_01795	9.077e-06	56.0	2AY0M@1|root,31Q26@2|Bacteria,2IMBI@201174|Actinobacteria,239D3@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
WLSH2_k127_2534061_3	596151.DesfrDRAFT_2296	4.338e-06	58.0	COG1075@1|root,COG1075@2|Bacteria,1NIPT@1224|Proteobacteria	1224|Proteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2551018_5	1007105.PT7_0650	1.002e-17	84.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T21B@506|Alcaligenaceae	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2551018_4	330214.NIDE2522	6.27e-51	192.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,3J10M@40117|Nitrospirae	40117|Nitrospirae	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WLSH2_k127_2551018_3	634956.Geoth_2890	8.998e-82	279.0	COG1028@1|root,COG1028@2|Bacteria,1UETI@1239|Firmicutes,4HB6V@91061|Bacilli,1WFNF@129337|Geobacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	fabG_4	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
WLSH2_k127_2551018_1	35841.BT1A1_2622	2.156e-118	399.0	COG1960@1|root,COG1960@2|Bacteria,1TR1Y@1239|Firmicutes,4HC1N@91061|Bacilli,1ZD47@1386|Bacillus	91061|Bacilli	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K06446	ko00930,ko01100,ko01120,map00930,map01100,map01120	-	R06943	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_2551018_0	398527.Bphyt_4084	1.985e-229	730.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1K035@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_2551018_2	1231391.AMZF01000069_gene2125	4.763e-104	345.0	COG2271@1|root,COG2271@2|Bacteria,1QTYR@1224|Proteobacteria	1224|Proteobacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_2564822_7	330214.NIDE2593	2.731e-09	64.0	2DCFZ@1|root,2ZDZV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2564822_5	1121033.AUCF01000001_gene2030	5.165e-79	274.0	COG0697@1|root,COG0697@2|Bacteria,1RCED@1224|Proteobacteria,2U66Q@28211|Alphaproteobacteria,2JRZ1@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_2564822_2	76114.c2A174	3.553e-95	319.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,2KVEY@206389|Rhodocyclales	206389|Rhodocyclales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH2_k127_2564822_1	375286.mma_1291	2.346e-117	388.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VJTU@28216|Betaproteobacteria,477DI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
WLSH2_k127_2564822_3	795666.MW7_0585	9.244e-94	319.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2564822_4	1458275.AZ34_06480	1.058e-86	298.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VPM0@28216|Betaproteobacteria,4ACTH@80864|Comamonadaceae	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_2564822_0	1163617.SCD_n01486	2.776e-169	539.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_2564822_6	1485544.JQKP01000002_gene1398	1.183e-66	229.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,44V7G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WLSH2_k127_2625313_9	1173021.ALWA01000035_gene3849	3.764e-18	85.0	COG3540@1|root,COG3540@2|Bacteria,1G0C9@1117|Cyanobacteria	1117|Cyanobacteria	P	alkaline phosphatase	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
WLSH2_k127_2625313_2	251221.35211762	2.98e-137	449.0	COG3540@1|root,COG3540@2|Bacteria,1G0C9@1117|Cyanobacteria	1117|Cyanobacteria	P	alkaline phosphatase	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
WLSH2_k127_2625313_8	1123393.KB891328_gene550	9.021e-29	125.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,1KRV8@119069|Hydrogenophilales	119069|Hydrogenophilales	J	S4 RNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	S4
WLSH2_k127_2625313_5	1163617.SCD_n02080	2.09e-50	186.0	COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2625313_3	522306.CAP2UW1_2028	2.784e-56	198.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2VSN3@28216|Betaproteobacteria,1KQUS@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
WLSH2_k127_2625313_1	1095769.CAHF01000014_gene3154	2.945e-190	607.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,2VPEG@28216|Betaproteobacteria,472QT@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Protein of unknown function (DUF4080)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
WLSH2_k127_2625313_7	1121935.AQXX01000005_gene681	2.448e-33	132.0	2CJPW@1|root,32SAH@2|Bacteria,1NAJ3@1224|Proteobacteria,1SAPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2625313_6	292415.Tbd_2635	1.704e-48	179.0	COG0494@1|root,COG0494@2|Bacteria,1MYSK@1224|Proteobacteria,2W3WC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH2_k127_2625313_4	204773.HEAR0752	6.091e-53	193.0	COG2755@1|root,COG2755@2|Bacteria,1RHMJ@1224|Proteobacteria,2W4YI@28216|Betaproteobacteria,476V3@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WLSH2_k127_2625313_0	1125973.JNLC01000010_gene1417	2.218e-216	686.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,3JZ96@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WLSH2_k127_2652620_1	1121033.AUCF01000036_gene3969	1.587e-82	282.0	COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,2JSE3@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
WLSH2_k127_2652620_3	1207063.P24_01395	6.677e-62	227.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5HA@28211|Alphaproteobacteria,2JRUX@204441|Rhodospirillales	204441|Rhodospirillales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
WLSH2_k127_2652620_0	62928.azo0150	1.305e-230	733.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
WLSH2_k127_2652620_2	2340.JV46_25540	2.322e-72	254.0	COG1024@1|root,COG1024@2|Bacteria,1MUD7@1224|Proteobacteria,1RSI6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Enoyl-CoA hydratase	rpfF	-	-	ko:K13816	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	ECH_1
WLSH2_k127_26674_2	1121937.AUHJ01000018_gene212	3.143e-30	124.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,465FU@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
WLSH2_k127_26674_0	1123377.AUIV01000015_gene276	1.593e-57	207.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1X68Z@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH2_k127_26674_1	1384054.N790_10990	3.478e-52	194.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,1SHAC@1236|Gammaproteobacteria,1X3IB@135614|Xanthomonadales	135614|Xanthomonadales	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
WLSH2_k127_2670382_0	1009370.ALO_11644	2.886e-185	597.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4H4MY@909932|Negativicutes	909932|Negativicutes	C	Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WLSH2_k127_2670382_1	1384484.AEQU_0598	7.374e-11	64.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4CVMC@84998|Coriobacteriia	84998|Coriobacteriia	C	4Fe-4S dicluster domain	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_4
WLSH2_k127_2691982_9	1288494.EBAPG3_18790	1.74e-70	246.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,2VRMX@28216|Betaproteobacteria,371UR@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_2691982_6	62928.azo2209	4.71e-110	360.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales	206389|Rhodocyclales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
WLSH2_k127_2691982_7	1266925.JHVX01000011_gene1486	5.558e-97	323.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,371NN@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
WLSH2_k127_2691982_10	748280.NH8B_0435	2.168e-54	197.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2VR6Y@28216|Betaproteobacteria,2KR7P@206351|Neisseriales	206351|Neisseriales	M	OmpW family	ompW	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
WLSH2_k127_2691982_2	640081.Dsui_1625	3.053e-253	806.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,2KV1V@206389|Rhodocyclales	206389|Rhodocyclales	P	cation transport ATPase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
WLSH2_k127_2691982_11	243365.CV_2041	1.378e-18	89.0	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,2VWG5@28216|Betaproteobacteria,2KS1K@206351|Neisseriales	206351|Neisseriales	P	cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
WLSH2_k127_2691982_5	1304883.KI912532_gene1738	1.144e-164	540.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KV4T@206389|Rhodocyclales	206389|Rhodocyclales	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
WLSH2_k127_2691982_8	159087.Daro_0834	7.435e-80	272.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,2KWA5@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WLSH2_k127_2691982_4	1132855.KB913035_gene1563	7.201e-223	697.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI6Q@28216|Betaproteobacteria,2KKB7@206350|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM Major Facilitator Superfamily	narK1	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
WLSH2_k127_2691982_1	296591.Bpro_4596	1.386e-277	861.0	COG2223@1|root,COG2223@2|Bacteria,1MU27@1224|Proteobacteria,2VI5E@28216|Betaproteobacteria,4ABQV@80864|Comamonadaceae	28216|Betaproteobacteria	P	nitrite transporter	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
WLSH2_k127_2691982_3	653733.Selin_2438	1.757e-231	723.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
WLSH2_k127_2691982_0	338969.Rfer_2792	0.0	1218.0	COG5013@1|root,COG5013@2|Bacteria,1MW9S@1224|Proteobacteria,2VJ2F@28216|Betaproteobacteria,4A9MX@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	narG	-	1.7.5.1	ko:K00370,ko:K17050	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Molybdopterin,Molydop_binding,Nitr_red_alph_N
WLSH2_k127_2746971_1	323848.Nmul_A2696	2.027e-142	458.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria,3722K@32003|Nitrosomonadales	28216|Betaproteobacteria	T	PhoH-like protein	ybeZ	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
WLSH2_k127_2746971_0	1288494.EBAPG3_8890	2.412e-217	681.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,371SR@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH2_k127_2843076_2	1163617.SCD_n00467	1.232e-167	533.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH2_k127_2843076_1	1266925.JHVX01000017_gene11	1.334e-176	562.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,372JY@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
WLSH2_k127_2843076_9	1301098.PKB_5681	4.275e-25	108.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,1SC8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center	rubA	-	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Rubredoxin
WLSH2_k127_2843076_7	1458275.AZ34_06480	3.4e-76	268.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VPM0@28216|Betaproteobacteria,4ACTH@80864|Comamonadaceae	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_2843076_3	1101195.Meth11DRAFT_1850	1.723e-136	442.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria,2KM4V@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
WLSH2_k127_2843076_8	76114.p2A140	2.867e-73	256.0	COG1414@1|root,COG1414@2|Bacteria,1NCG5@1224|Proteobacteria,2VWMK@28216|Betaproteobacteria,2KZKC@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
WLSH2_k127_2843076_5	365046.Rta_29380	5.833e-88	302.0	COG3181@1|root,COG3181@2|Bacteria,1R6S3@1224|Proteobacteria,2VHD5@28216|Betaproteobacteria,4AADY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2843076_6	365046.Rta_29380	6.505e-88	301.0	COG3181@1|root,COG3181@2|Bacteria,1R6S3@1224|Proteobacteria,2VHD5@28216|Betaproteobacteria,4AADY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2843076_0	420324.KI912086_gene7328	3.294e-201	636.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,1JU3D@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3,DUF1643
WLSH2_k127_2843076_4	1054213.HMPREF9946_00792	3.492e-94	317.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
WLSH2_k127_2843076_10	1366050.N234_10410	9.257e-16	81.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2888823_2	404589.Anae109_1864	1.419e-134	441.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2YV6M@29|Myxococcales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
WLSH2_k127_2888823_3	1123020.AUIE01000002_gene1374	6.708e-85	287.0	COG2928@1|root,COG2928@2|Bacteria,1RK8I@1224|Proteobacteria,1S53Q@1236|Gammaproteobacteria,1YFD1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
WLSH2_k127_2888823_0	1197906.CAJQ02000010_gene3376	5.087e-218	690.0	COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,2TV53@28211|Alphaproteobacteria,3JQPF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
WLSH2_k127_2888823_1	1211777.BN77_p10820	5.622e-155	497.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2TS4V@28211|Alphaproteobacteria,4BBFX@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WLSH2_k127_2888823_4	1120970.AUBZ01000009_gene2050	1.918e-32	134.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,1RNZM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in outer membrane biogenesis	yhjG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA
WLSH2_k127_2902438_1	1122604.JONR01000039_gene3778	2.475e-115	375.0	COG2521@1|root,COG2521@2|Bacteria,1Q0VI@1224|Proteobacteria,1S18J@1236|Gammaproteobacteria,1XC99@135614|Xanthomonadales	135614|Xanthomonadales	S	Methyl-transferase	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_30
WLSH2_k127_2902438_0	768671.ThimaDRAFT_0417	6.403e-165	524.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,1WX9A@135613|Chromatiales	135613|Chromatiales	GM	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WLSH2_k127_2902438_2	1268622.AVS7_04525	4.141e-88	304.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_2948989_2	396588.Tgr7_0491	1.343e-19	90.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	yafP	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
WLSH2_k127_2948989_1	1121939.L861_12520	2.967e-67	231.0	COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria,1XPBP@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TM2
WLSH2_k127_2948989_3	1265313.HRUBRA_00305	1.366e-16	85.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria,1J702@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
WLSH2_k127_2948989_4	1380394.JADL01000002_gene1148	5.768e-09	64.0	2DNEG@1|root,32X40@2|Bacteria,1R7P4@1224|Proteobacteria	1224|Proteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
WLSH2_k127_2948989_0	338969.Rfer_3394	2.509e-92	311.0	COG3115@1|root,COG3115@2|Bacteria,1QWGJ@1224|Proteobacteria,2WGZ3@28216|Betaproteobacteria,4AH94@80864|Comamonadaceae	28216|Betaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2964020_0	204773.HEAR0070	1.128e-131	426.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,4737W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WLSH2_k127_2964020_1	1049564.TevJSym_ao00520	8.894e-98	323.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,1J5ZG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	cysQ	GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	iAPECO1_1312.APECO1_2172,iE2348C_1286.E2348C_4545,iEC042_1314.EC042_4695,iEC55989_1330.EC55989_4774,iECABU_c1320.ECABU_c47840,iECIAI1_1343.ECIAI1_4448,iECIAI39_1322.ECIAI39_4686,iECO103_1326.ECO103_5013,iECO111_1330.ECO111_5101,iECO26_1355.ECO26_5384,iECOK1_1307.ECOK1_4735,iECP_1309.ECP_4468,iECSE_1348.ECSE_4520,iECSF_1327.ECSF_4108,iECUMN_1333.ECUMN_4751,iECW_1372.ECW_m4578,iEKO11_1354.EKO11_4094,iEcE24377_1341.EcE24377A_4785,iEcHS_1320.EcHS_A4468,iEcSMS35_1347.EcSMS35_4694,iLF82_1304.LF82_0422,iNRG857_1313.NRG857_21455,iSBO_1134.SBO_4229,iSDY_1059.SDY_4385,iSSON_1240.SSON_4399,iSbBS512_1146.SbBS512_E4758,iUMN146_1321.UM146_21355,iUTI89_1310.UTI89_C4823,iWFL_1372.ECW_m4578,ic_1306.c5313	Inositol_P
WLSH2_k127_2990153_1	375286.mma_3208	3.045e-114	378.0	COG4591@1|root,COG4591@2|Bacteria,1QUPC@1224|Proteobacteria,2WGKM@28216|Betaproteobacteria,4791A@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_2990153_3	1504672.669786190	3.71e-17	83.0	2EBIQ@1|root,335J5@2|Bacteria,1N8P7@1224|Proteobacteria,2VX7H@28216|Betaproteobacteria,4AFDY@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_2990153_2	375286.mma_3209	6.654e-42	160.0	COG3495@1|root,COG3495@2|Bacteria,1RFBI@1224|Proteobacteria,2VRJ9@28216|Betaproteobacteria,477HV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3299)	-	-	-	ko:K09950	-	-	-	-	ko00000	-	-	-	DUF3299
WLSH2_k127_2990153_0	582744.Msip34_0169	3.711e-210	678.0	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,2WGGE@28216|Betaproteobacteria,2KM9M@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WLSH2_k127_3013756_7	159087.Daro_0609	6.266e-30	131.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,2KV1S@206389|Rhodocyclales	206389|Rhodocyclales	D	peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH2_k127_3013756_0	557598.LHK_02762	5.764e-201	637.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,2KQ14@206351|Neisseriales	206351|Neisseriales	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
WLSH2_k127_3013756_3	292415.Tbd_2395	2.255e-43	160.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,1KT6W@119069|Hydrogenophilales	119069|Hydrogenophilales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
WLSH2_k127_3013756_6	265072.Mfla_2187	3.829e-33	135.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,2KN1N@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_3013756_4	1175306.GWL_43410	7.253e-38	144.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,474TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
WLSH2_k127_3013756_2	1163617.SCD_n02690	3.814e-50	182.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
WLSH2_k127_3013756_5	62928.azo2813	5.9e-35	138.0	COG3807@1|root,COG3807@2|Bacteria,1MZIA@1224|Proteobacteria,2VUTD@28216|Betaproteobacteria,2KWXG@206389|Rhodocyclales	206389|Rhodocyclales	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
WLSH2_k127_3013756_1	1454004.AW11_01927	2.143e-110	366.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,1KQ8G@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WLSH2_k127_3013756_8	1158165.KB898871_gene2262	4.769e-21	93.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1WY8C@135613|Chromatiales	135613|Chromatiales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WLSH2_k127_3038388_2	420324.KI911965_gene1219	4.562e-55	214.0	COG0515@1|root,COG0589@1|root,COG0515@2|Bacteria,COG0589@2|Bacteria,1MV1P@1224|Proteobacteria,2TQTS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	MA20_09295	-	-	-	-	-	-	-	-	-	-	-	Pkinase,Usp
WLSH2_k127_3038388_3	648757.Rvan_2347	5.075e-50	187.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,2TSFT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WLSH2_k127_3038388_1	522306.CAP2UW1_0009	3.001e-68	236.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2VN1I@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
WLSH2_k127_3038388_0	1288494.EBAPG3_7890	1.398e-116	390.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,372C3@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Signal transduction histidine kinase	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WLSH2_k127_3038388_4	1123368.AUIS01000013_gene815	4.441e-36	142.0	COG4313@1|root,COG4313@2|Bacteria,1R5Z9@1224|Proteobacteria,1T97C@1236|Gammaproteobacteria,2NDZP@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_304870_0	861299.J421_0838	7.003e-173	553.0	COG0446@1|root,COG2146@1|root,COG0446@2|Bacteria,COG2146@2|Bacteria,1ZV6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WLSH2_k127_304870_1	754476.Q7A_235	1.327e-53	197.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,461AW@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Bacterial protein of	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
WLSH2_k127_304870_2	2340.JV46_06120	1.562e-12	70.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,1RMF8@1236|Gammaproteobacteria,1J5MC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative neutral zinc metallopeptidase	ypfJ	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
WLSH2_k127_3065988_3	1163617.SCD_n02359	1.648e-33	139.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
WLSH2_k127_3065988_1	1163617.SCD_n02360	9.737e-155	500.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
WLSH2_k127_3065988_2	1163617.SCD_n00753	6.275e-130	428.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
WLSH2_k127_3065988_0	153948.NAL212_1449	8.061e-186	586.0	COG1398@1|root,COG3464@1|root,COG1398@2|Bacteria,COG3464@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,37215@32003|Nitrosomonadales	28216|Betaproteobacteria	I	fatty acid desaturase	ole1	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
WLSH2_k127_3065988_5	279714.FuraDRAFT_1130	7.041e-20	93.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,2KRX9@206351|Neisseriales	206351|Neisseriales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
WLSH2_k127_3065988_4	1283300.ATXB01000001_gene2017	5.425e-33	129.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,1XFJ2@135618|Methylococcales	135618|Methylococcales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WLSH2_k127_3141950_12	1288494.EBAPG3_21670	1.253e-64	222.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,371NY@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH2_k127_3141950_0	1163617.SCD_n02700	4.033e-203	641.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WLSH2_k127_3141950_5	1163617.SCD_n02701	5.195e-111	363.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
WLSH2_k127_3141950_10	1266925.JHVX01000013_gene1647	3.665e-74	256.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,372QG@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
WLSH2_k127_3141950_6	580332.Slit_0736	8.189e-88	295.0	COG0637@1|root,COG0637@2|Bacteria,1QTWD@1224|Proteobacteria,2VNTW@28216|Betaproteobacteria,44UZ1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WLSH2_k127_3141950_2	1288494.EBAPG3_21640	1.329e-150	480.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,3729E@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
WLSH2_k127_3141950_15	580332.Slit_0734	3.736e-47	174.0	COG0071@1|root,COG0071@2|Bacteria,1PV6Z@1224|Proteobacteria,2WA7J@28216|Betaproteobacteria,44WMZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH2_k127_3141950_13	977880.RALTA_B2177	2.715e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,1K198@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_3141950_17	1454004.AW11_02742	6.787e-09	58.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria	1224|Proteobacteria	S	Transmembrane anti-sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WLSH2_k127_3141950_3	323848.Nmul_A1991	3.533e-149	482.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,3721U@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
WLSH2_k127_3141950_4	1163617.SCD_n00104	9.324e-125	407.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Aminotransferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
WLSH2_k127_3141950_16	323848.Nmul_A1989	1.574e-28	119.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,373HP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0250 family	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
WLSH2_k127_3141950_11	1304883.KI912532_gene59	1.311e-73	254.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria,2KWDP@206389|Rhodocyclales	206389|Rhodocyclales	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
WLSH2_k127_3141950_8	76114.ebA3048	2.825e-78	269.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,2KW5V@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WLSH2_k127_3141950_1	323848.Nmul_A1987	7.612e-158	506.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,371U2@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WLSH2_k127_3141950_14	1349767.GJA_5470	1.944e-56	202.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria,47435@75682|Oxalobacteraceae	28216|Betaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
WLSH2_k127_3141950_9	1485544.JQKP01000002_gene1412	1.446e-76	263.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,44VSN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
WLSH2_k127_3141950_7	497964.CfE428DRAFT_2577	1.892e-79	273.0	COG1541@1|root,COG1541@2|Bacteria,46WQ5@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
WLSH2_k127_3189468_3	1003200.AXXA_24370	2.475e-146	478.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VM6J@28216|Betaproteobacteria,3T1T9@506|Alcaligenaceae	28216|Betaproteobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	mdlB	-	1.1.2.3	ko:K00101	ko00620,ko01100,map00620,map01100	-	R00196	RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
WLSH2_k127_3189468_16	1348657.M622_09750	5.845e-09	66.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,2KW20@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
WLSH2_k127_3189468_7	1205680.CAKO01000002_gene2378	4.169e-112	369.0	COG2175@1|root,COG2175@2|Bacteria,1MVI6@1224|Proteobacteria,2TVHF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	PFAM Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	ko:K06912	ko00361,ko01120,ko01220,map00361,map01120,map01220	-	R05419,R05493	RC01371,RC01372	ko00000,ko00001,ko01000	-	-	-	TauD
WLSH2_k127_3189468_14	1211115.ALIQ01000183_gene2912	5.714e-29	120.0	COG5470@1|root,COG5470@2|Bacteria,1N012@1224|Proteobacteria,2VG1G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
WLSH2_k127_3189468_1	1000565.METUNv1_01897	3.512e-276	861.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,2KUTU@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
WLSH2_k127_3189468_8	204773.HEAR3341	1.404e-109	366.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2W9V3@28216|Betaproteobacteria,477UM@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Malate/L-lactate dehydrogenase	-	-	1.1.1.338	ko:K16844	ko00270,ko01120,map00270,map01120	-	R07137	RC00031	ko00000,ko00001,ko01000	-	-	-	Ldh_2
WLSH2_k127_3189468_11	1157708.KB907460_gene1482	1.406e-78	274.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJBE@28216|Betaproteobacteria,4ACD2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_3189468_0	795666.MW7_3397	9.956e-281	871.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VI6D@28216|Betaproteobacteria,1K5TM@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WLSH2_k127_3189468_9	795666.MW7_3398	2.014e-98	325.0	COG1838@1|root,COG1838@2|Bacteria,1MVNG@1224|Proteobacteria,2VMDH@28216|Betaproteobacteria,1K6CN@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Fumarase C-terminus	-	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
WLSH2_k127_3189468_4	713586.KB900536_gene706	1.431e-142	456.0	COG1951@1|root,COG1951@2|Bacteria,1MW8J@1224|Proteobacteria,1RPUD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Tartrate	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
WLSH2_k127_3189468_10	795666.MW7_3003	1.576e-95	325.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKMJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_3189468_5	344747.PM8797T_15706	3.644e-119	398.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
WLSH2_k127_3189468_12	713586.KB900536_gene708	8.732e-42	158.0	COG2009@1|root,COG2009@2|Bacteria,1N8VA@1224|Proteobacteria	1224|Proteobacteria	C	succinate dehydrogenase	-	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WLSH2_k127_3189468_13	713586.KB900536_gene709	1.907e-32	130.0	COG2142@1|root,COG2142@2|Bacteria,1MZKE@1224|Proteobacteria	1224|Proteobacteria	C	succinate dehydrogenase	-	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WLSH2_k127_3189468_6	713586.KB900536_gene710	6.689e-115	374.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales	1236|Gammaproteobacteria	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_3,Fer4_17,Fer4_8
WLSH2_k127_3189468_2	795666.MW7_3395	6.95e-181	582.0	COG0028@1|root,COG0028@2|Bacteria,1R6FF@1224|Proteobacteria,2WF6X@28216|Betaproteobacteria,1KHZB@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WLSH2_k127_3284602_12	1163617.SCD_n02226	4.503e-49	183.0	COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
WLSH2_k127_3284602_8	883126.HMPREF9710_00547	3.788e-125	411.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,475ID@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
WLSH2_k127_3284602_10	1411123.JQNH01000001_gene964	1.27e-97	322.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Belongs to the GST superfamily	MA20_22025	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N,GST_N_3
WLSH2_k127_3284602_4	272134.KB731324_gene5268	1.027e-140	468.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria	1117|Cyanobacteria	S	Zinc-binding alcohol dehydrogenase family protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_3284602_13	1000565.METUNv1_03628	4.892e-42	169.0	28TB7@1|root,2ZFJR@2|Bacteria,1PACM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3284602_7	265072.Mfla_0230	1.26e-137	448.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,2KKBV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
WLSH2_k127_3284602_9	1288494.EBAPG3_17670	8.631e-98	326.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,371ZM@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH2_k127_3284602_5	1071679.BG57_25455	1.117e-139	449.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,1K0VT@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
WLSH2_k127_3284602_11	543728.Vapar_0801	2.275e-71	253.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJCY@28216|Betaproteobacteria,4ABM4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_3284602_2	556268.OFAG_02107	2.157e-194	620.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VNWB@28216|Betaproteobacteria,478EE@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WLSH2_k127_3284602_6	887062.HGR_04393	1.195e-137	450.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria,4AIFH@80864|Comamonadaceae	28216|Betaproteobacteria	P	Divalent cation transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WLSH2_k127_3284602_3	1288494.EBAPG3_11640	6.189e-145	464.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,3728C@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
WLSH2_k127_3284602_0	519989.ECTPHS_03834	1.572e-241	756.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1WVY5@135613|Chromatiales	135613|Chromatiales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WLSH2_k127_3284602_1	1163617.SCD_n00307	4.251e-205	643.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WLSH2_k127_3284602_15	1163617.SCD_n02538	4.405e-38	151.0	COG0810@1|root,COG0810@2|Bacteria,1NATT@1224|Proteobacteria,2VWBE@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WLSH2_k127_3284602_14	1163617.SCD_n00205	6.253e-41	152.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transferase hexapeptide	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WLSH2_k127_3395034_2	596154.Alide2_4534	1.914e-91	309.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4ABD6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_3395034_4	1123504.JQKD01000004_gene5109	1.811e-69	246.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2W8XT@28216|Betaproteobacteria,4AHNC@80864|Comamonadaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH2_k127_3395034_1	426716.JOAJ01000011_gene6506	3.666e-148	487.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4G5E4@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_3395034_3	1123060.JONP01000007_gene4984	2.453e-72	252.0	COG0596@1|root,COG0596@2|Bacteria,1R9EZ@1224|Proteobacteria,2U44G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_3395034_6	316056.RPC_1073	9.459e-35	137.0	COG1545@1|root,COG1545@2|Bacteria,1N2C8@1224|Proteobacteria,2U8C7@28211|Alphaproteobacteria,3K4WC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
WLSH2_k127_3395034_0	596154.Alide2_1159	5.792e-180	570.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VKT6@28216|Betaproteobacteria,4AH6V@80864|Comamonadaceae	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
WLSH2_k127_3395034_7	1380394.JADL01000003_gene4948	1.155e-32	136.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VEZC@28211|Alphaproteobacteria,2JU3P@204441|Rhodospirillales	204441|Rhodospirillales	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
WLSH2_k127_3395034_5	397945.Aave_3268	1.962e-40	161.0	COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,2VJ7W@28216|Betaproteobacteria,4ADUX@80864|Comamonadaceae	28216|Betaproteobacteria	P	extracellular solute-binding protein, family 1	-	-	5.3.3.7	ko:K22003	ko00660,map00660	-	R02244	RC00668	ko00000,ko00001,ko01000	-	-	-	SBP_bac_11
WLSH2_k127_3395034_8	1156919.QWC_11111	2.118e-09	61.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJ08@28216|Betaproteobacteria,3T5HZ@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_3452272_0	1288494.EBAPG3_4370	0.0	1344.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,372Q5@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
WLSH2_k127_3452272_7	323848.Nmul_A0480	3.253e-74	253.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,372P1@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WLSH2_k127_3452272_8	1304883.KI912532_gene29	2.157e-55	198.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria,2KWU0@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
WLSH2_k127_3452272_9	580332.Slit_1059	3.66e-31	126.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,44VYX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	CRS1_YhbY	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
WLSH2_k127_3452272_6	1211114.ALIP01000156_gene3051	3.32e-78	266.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1X4P6@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
WLSH2_k127_3452272_1	1163617.SCD_n00924	0.0	1072.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WLSH2_k127_3452272_4	292415.Tbd_1134	1.094e-106	353.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WLSH2_k127_3452272_2	1163617.SCD_n00926	2.83e-185	588.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH2_k127_3452272_3	543913.D521_0790	4.736e-141	451.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WLSH2_k127_3452272_5	358220.C380_09285	1.363e-92	306.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,4ABXP@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_3547208_1	323848.Nmul_A0510	2.85e-139	453.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VZIT@28216|Betaproteobacteria,371QJ@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_3547208_2	234267.Acid_2378	1.207e-94	322.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Fib_succ_major
WLSH2_k127_3547208_0	543728.Vapar_0459	2.617e-222	707.0	COG4122@1|root,COG4122@2|Bacteria,1QWCT@1224|Proteobacteria,2VJBK@28216|Betaproteobacteria,4ACMD@80864|Comamonadaceae	28216|Betaproteobacteria	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3547208_3	266264.Rmet_5061	1.308e-34	136.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJH2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_3574040_8	1123368.AUIS01000007_gene2779	6.146e-52	185.0	COG2044@1|root,COG2044@2|Bacteria,1N7MM@1224|Proteobacteria,1SCQA@1236|Gammaproteobacteria,2NCTS@225057|Acidithiobacillales	225057|Acidithiobacillales	S	DsrE/DsrF-like family	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE
WLSH2_k127_3574040_6	519989.ECTPHS_10871	7.366e-59	209.0	COG0509@1|root,COG0509@2|Bacteria,1RKRS@1224|Proteobacteria,1T0BR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	-	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WLSH2_k127_3574040_1	396588.Tgr7_2207	9.681e-162	516.0	COG1856@1|root,COG1856@2|Bacteria,1R6PW@1224|Proteobacteria,1SKHD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
WLSH2_k127_3574040_3	1163617.SCD_n00803	6.664e-154	494.0	COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,2VQNY@28216|Betaproteobacteria	28216|Betaproteobacteria	H	lipoate-protein ligase A	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WLSH2_k127_3574040_4	519989.ECTPHS_10886	3.245e-113	378.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored,GIDA,Lycopene_cycl
WLSH2_k127_3574040_7	316058.RPB_4374	7.559e-54	194.0	COG3193@1|root,COG3193@2|Bacteria,1REF5@1224|Proteobacteria,2U5M2@28211|Alphaproteobacteria,3JYF2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
WLSH2_k127_3574040_0	396588.Tgr7_2204	4.159e-198	621.0	COG2516@1|root,COG2516@2|Bacteria,1MWZQ@1224|Proteobacteria,1RY3C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
WLSH2_k127_3574040_5	1123393.KB891327_gene473	2.882e-77	263.0	COG2210@1|root,COG2210@2|Bacteria,1QCK1@1224|Proteobacteria,2WE8S@28216|Betaproteobacteria,1KSAI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
WLSH2_k127_3574040_2	1123392.AQWL01000004_gene2720	3.787e-159	513.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,1KT8K@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
WLSH2_k127_3574040_10	637389.Acaty_c2181	6.029e-36	140.0	2F8JF@1|root,340Y7@2|Bacteria,1NYW2@1224|Proteobacteria,1SQHY@1236|Gammaproteobacteria,2NCY0@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3574040_9	1123368.AUIS01000007_gene2770	2.457e-49	187.0	COG0095@1|root,COG0095@2|Bacteria,1RDZE@1224|Proteobacteria,1SQ47@1236|Gammaproteobacteria,2NCC2@225057|Acidithiobacillales	225057|Acidithiobacillales	H	PFAM biotin lipoate A B protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3575618_4	395494.Galf_1754	5.296e-83	276.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,44VCA@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH2_k127_3575618_2	153948.NAL212_0716	1.591e-218	696.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,3727P@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WLSH2_k127_3575618_0	640081.Dsui_2297	7.299e-299	931.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2VKAN@28216|Betaproteobacteria,2KVQH@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-coenzyme A synthetase N-terminus	acsA	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WLSH2_k127_3575618_1	323848.Nmul_A2276	2.275e-270	852.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,371WG@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Heavy metal transport detoxification protein	copA	-	3.6.3.54	ko:K17686,ko:K19597	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.5.20	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH2_k127_3575618_6	1120919.AUBI01000001_gene3237	5.675e-14	74.0	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria	1224|Proteobacteria	P	heavy metal transport detoxification protein	copP	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
WLSH2_k127_3575618_5	323848.Nmul_A2278	1.801e-33	132.0	COG1937@1|root,COG1937@2|Bacteria,1N9P2@1224|Proteobacteria,2VUK5@28216|Betaproteobacteria,373DZ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WLSH2_k127_3575618_3	522306.CAP2UW1_3923	4.69e-97	321.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KQ3X@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
WLSH2_k127_3579868_8	1003200.AXXA_12145	6.463e-09	58.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VU1T@28216|Betaproteobacteria	28216|Betaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_3579868_4	795666.MW7_0585	1.391e-93	317.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_3579868_1	1123504.JQKD01000005_gene4907	1.987e-195	627.0	COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2VMUI@28216|Betaproteobacteria,4AGNX@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WLSH2_k127_3579868_5	795666.MW7_0585	4.733e-91	309.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_3579868_2	1463857.JOFZ01000001_gene5441	1.78e-110	370.0	COG2159@1|root,COG2159@2|Bacteria,2HEB4@201174|Actinobacteria	201174|Actinobacteria	CH	amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
WLSH2_k127_3579868_3	1123060.JONP01000012_gene2840	2.163e-96	322.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2U5IJ@28211|Alphaproteobacteria,2JTWG@204441|Rhodospirillales	204441|Rhodospirillales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH2_k127_3579868_0	1463857.JOFZ01000001_gene5444	5.139e-314	996.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
WLSH2_k127_3579868_7	1123288.SOV_1c06600	4.038e-46	171.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,4H5AR@909932|Negativicutes	909932|Negativicutes	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
WLSH2_k127_3579868_6	688270.Celal_1430	2.632e-69	249.0	2DB7P@1|root,2Z7MR@2|Bacteria,4NKTK@976|Bacteroidetes,1IEN9@117743|Flavobacteriia,1F9X3@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3762930_0	1485544.JQKP01000002_gene1453	2.676e-277	856.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,44V3Z@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH2_k127_3762930_1	395494.Galf_2873	1.944e-174	548.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,44VEV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Phosphoribulokinase / Uridine kinase family	cbbP	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
WLSH2_k127_3769586_2	1163617.SCD_n00224	6.967e-60	209.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_3769586_0	1288494.EBAPG3_7180	0.0	1808.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,372NK@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WLSH2_k127_3769586_3	870187.Thini_3899	7.182e-54	200.0	COG1266@1|root,COG1266@2|Bacteria,1QSFU@1224|Proteobacteria	1224|Proteobacteria	S	CAAX amino Terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH2_k127_3769586_1	667632.KB890176_gene4482	1.825e-84	288.0	COG5285@1|root,COG5285@2|Bacteria,1RC3C@1224|Proteobacteria,2VQ3Y@28216|Betaproteobacteria,1KHBQ@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	phytanoyl-CoA dioxygenase	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
WLSH2_k127_3769586_4	172088.AUGA01000034_gene5096	1.03e-30	122.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2TQT2@28211|Alphaproteobacteria,3JTS4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_3778037_0	1123393.KB891316_gene1630	0.0	1026.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSAB@119069|Hydrogenophilales	119069|Hydrogenophilales	V	Patched family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WLSH2_k127_3778037_1	1123257.AUFV01000007_gene116	7.899e-35	141.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,1RQ67@1236|Gammaproteobacteria,1XA98@135614|Xanthomonadales	135614|Xanthomonadales	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
WLSH2_k127_3917427_2	1112217.PPL19_12528	1.807e-55	197.0	COG4696@1|root,COG4696@2|Bacteria,1N92T@1224|Proteobacteria,1SP95@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3917427_0	1095769.CAHF01000005_gene1469	2.064e-305	953.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria	28216|Betaproteobacteria	J	elongation factor G	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
WLSH2_k127_3917427_4	1131553.JIBI01000026_gene79	3.623e-53	189.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,373EC@32003|Nitrosomonadales	28216|Betaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
WLSH2_k127_3917427_5	1054213.HMPREF9946_03236	3.23e-43	166.0	COG4126@1|root,COG4126@2|Bacteria,1MWVG@1224|Proteobacteria,2U0MW@28211|Alphaproteobacteria,2JWTC@204441|Rhodospirillales	204441|Rhodospirillales	E	Asp Glu hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_3917427_3	1192034.CAP_5919	2.35e-54	198.0	COG4300@1|root,COG4300@2|Bacteria,1PNFJ@1224|Proteobacteria,434SI@68525|delta/epsilon subdivisions,2WZ3K@28221|Deltaproteobacteria,2Z197@29|Myxococcales	28221|Deltaproteobacteria	P	Cadmium resistance transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cad
WLSH2_k127_3917427_1	338969.Rfer_3468	7.793e-63	218.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2VTC8@28216|Betaproteobacteria,4AIEB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WLSH2_k127_3917427_7	395493.BegalDRAFT_0733	5.722e-23	106.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4608A@72273|Thiotrichales	72273|Thiotrichales	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K10715	ko02020,ko02024,map02020,map02024	M00517	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
WLSH2_k127_3917427_8	1038860.AXAP01000082_gene501	1.551e-09	61.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria,3JUX0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
WLSH2_k127_4153483_9	864051.BurJ1DRAFT_2540	4.558e-19	89.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,1KM3E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
WLSH2_k127_4153483_4	323848.Nmul_A1208	4.135e-73	256.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,372UU@32003|Nitrosomonadales	28216|Betaproteobacteria	CO	oxidoreductase DsbE	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
WLSH2_k127_4153483_0	1131553.JIBI01000009_gene1231	2.629e-307	954.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,3725U@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WLSH2_k127_4153483_6	522306.CAP2UW1_0724	1.758e-59	209.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,1KQQX@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
WLSH2_k127_4153483_10	1163617.SCD_n02737	8.041e-12	66.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY2T@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
WLSH2_k127_4153483_1	1163617.SCD_n02738	2.128e-118	385.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
WLSH2_k127_4153483_3	1288494.EBAPG3_12810	6.818e-78	270.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,371Q1@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
WLSH2_k127_4153483_5	1131553.JIBI01000009_gene1227	1.738e-61	218.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,372UK@32003|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
WLSH2_k127_4153483_7	1223521.BBJX01000002_gene2691	4.119e-48	182.0	COG2067@1|root,COG2067@2|Bacteria,1N1F4@1224|Proteobacteria,2VW9Z@28216|Betaproteobacteria	28216|Betaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
WLSH2_k127_4153483_2	596154.Alide2_3373	9.258e-99	331.0	COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2VJI6@28216|Betaproteobacteria,4AAH2@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the ribose-phosphate pyrophosphokinase family	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
WLSH2_k127_4153483_8	596154.Alide2_2726	2.288e-45	168.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2VHXI@28216|Betaproteobacteria,4AB63@80864|Comamonadaceae	28216|Betaproteobacteria	F	thymidine phosphorylase	deoA	-	2.4.2.4	ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WLSH2_k127_4165291_3	1304883.KI912532_gene1300	2.163e-158	507.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,2KVMP@206389|Rhodocyclales	206389|Rhodocyclales	S	sulfide dehydrogenase	soxF	-	1.8.2.1	ko:K05301	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528	RC00168	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
WLSH2_k127_4165291_13	1288494.EBAPG3_8750	1.506e-38	149.0	2E0X2@1|root,32WE0@2|Bacteria,1R38G@1224|Proteobacteria,2VV4E@28216|Betaproteobacteria,373CI@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
WLSH2_k127_4165291_5	76114.ebA4460	1.464e-109	362.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,2KVPB@206389|Rhodocyclales	206389|Rhodocyclales	P	Rhodanese Homology Domain	tst	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WLSH2_k127_4165291_2	1266925.JHVX01000005_gene2011	2.815e-179	567.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,372FN@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM Rieske 2Fe-2S	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
WLSH2_k127_4165291_11	522306.CAP2UW1_2820	3.555e-52	193.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,2WAF1@28216|Betaproteobacteria,1KQX7@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
WLSH2_k127_4165291_12	1454004.AW11_02740	4.377e-48	180.0	COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,2VRM0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
WLSH2_k127_4165291_7	1411123.JQNH01000001_gene1175	5.678e-81	275.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2TXAA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
WLSH2_k127_4165291_6	395495.Lcho_1708	2.098e-94	317.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,2VP38@28216|Betaproteobacteria,1KN8D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
WLSH2_k127_4165291_0	522306.CAP2UW1_2826	0.0	1035.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KQAC@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	SNARE associated Golgi protein	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
WLSH2_k127_4165291_8	626418.bglu_2p1130	3.498e-76	267.0	COG0639@1|root,COG0639@2|Bacteria,1PXN4@1224|Proteobacteria	1224|Proteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WLSH2_k127_4165291_1	1454004.AW11_02718	2.62e-194	624.0	COG0591@1|root,COG0591@2|Bacteria,1PKDE@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WLSH2_k127_4165291_4	864051.BurJ1DRAFT_3428	9.064e-149	477.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,2VKSA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3641)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
WLSH2_k127_4165291_9	1280950.HJO_09059	1.099e-54	199.0	COG2128@1|root,COG2128@2|Bacteria,1N56H@1224|Proteobacteria,2UABU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WLSH2_k127_4165291_10	1395571.TMS3_0117510	3.846e-53	191.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,1S60I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF302
WLSH2_k127_4195650_6	278963.ATWD01000001_gene2502	7.294e-06	54.0	COG1984@1|root,COG1984@2|Bacteria	2|Bacteria	E	allophanate hydrolase subunit 2	kipA	-	6.3.4.6	ko:K01941,ko:K06350	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	CT_A_B,CT_C_D,SLH
WLSH2_k127_4195650_0	1123392.AQWL01000001_gene1423	2.406e-98	326.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1KSPA@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
WLSH2_k127_4195650_1	292415.Tbd_2046	3.749e-87	294.0	COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,2VSP5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	DSBA-like thioredoxin domain	-	-	-	ko:K07396	-	-	-	-	ko00000	-	-	-	DSBA,Thioredoxin_5
WLSH2_k127_4195650_3	1117314.PCIT_08063	4.293e-43	160.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6G@1224|Proteobacteria,1S941@1236|Gammaproteobacteria,2Q3JA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
WLSH2_k127_4195650_2	582744.Msip34_1224	1.946e-86	290.0	COG0778@1|root,COG0778@2|Bacteria,1RBZQ@1224|Proteobacteria,2VQTZ@28216|Betaproteobacteria,2KP6W@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_4195650_4	1123393.KB891328_gene615	8.049e-40	148.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,1KTCC@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Sulfurtransferase TusA	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
WLSH2_k127_4195650_5	1123393.KB891316_gene1349	3.579e-22	96.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,1KRHF@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Putative metal-binding domain of cation transport ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
WLSH2_k127_4221580_0	1187851.A33M_4209	1.029e-103	364.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
WLSH2_k127_4221580_4	2340.JV46_16940	0.0007277	53.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.2.7.1	ko:K03737,ko:K05337	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
WLSH2_k127_4221580_2	1121035.AUCH01000001_gene2104	4.098e-45	175.0	COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,2WGZA@28216|Betaproteobacteria,2KWAH@206389|Rhodocyclales	206389|Rhodocyclales	U	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
WLSH2_k127_4221580_3	582744.Msip34_0442	9.729e-41	155.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,2KMWD@206350|Nitrosomonadales	206350|Nitrosomonadales	M	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
WLSH2_k127_4221580_1	977880.RALTA_A0747	6.287e-52	188.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1JZVS@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	fbpA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
WLSH2_k127_4266160_14	1123487.KB892835_gene3585	5.664e-38	142.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,2KUY5@206389|Rhodocyclales	206389|Rhodocyclales	E	ABC-type polar amino acid transport system, ATPase component	-	-	-	ko:K10004	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	ABC_tran
WLSH2_k127_4266160_12	1267005.KB911260_gene3526	2.344e-42	160.0	COG0727@1|root,COG0727@2|Bacteria,1N5PC@1224|Proteobacteria,2UFEE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
WLSH2_k127_4266160_2	1207063.P24_11802	1.296e-142	465.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,2JPUE@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the peptidase M20A family. ArgE subfamily	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
WLSH2_k127_4266160_1	1144319.PMI16_00252	2.09e-188	605.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VHCV@28216|Betaproteobacteria,47309@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	dppA2	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH2_k127_4266160_5	1207063.P24_03900	4.071e-98	326.0	COG2988@1|root,COG2988@2|Bacteria,1QW6K@1224|Proteobacteria,2TWQ0@28211|Alphaproteobacteria,2JYWE@204441|Rhodospirillales	204441|Rhodospirillales	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
WLSH2_k127_4266160_16	1380394.JADL01000017_gene497	5.095e-17	81.0	COG2988@1|root,COG2988@2|Bacteria,1QW6K@1224|Proteobacteria,2TWQ0@28211|Alphaproteobacteria,2JYWE@204441|Rhodospirillales	204441|Rhodospirillales	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
WLSH2_k127_4266160_3	375286.mma_3521	9.945e-135	436.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VHEF@28216|Betaproteobacteria,473V3@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport system, permease component	dppB2	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WLSH2_k127_4266160_4	1380394.JADL01000010_gene4344	3.678e-109	383.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2TT4V@28211|Alphaproteobacteria,2JPM9@204441|Rhodospirillales	204441|Rhodospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WLSH2_k127_4266160_9	266264.Rmet_3671	5.86e-78	274.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_4266160_6	1120956.JHZK01000002_gene1027	1.221e-96	325.0	COG2175@1|root,COG2175@2|Bacteria,1Q8GZ@1224|Proteobacteria,2VCP6@28211|Alphaproteobacteria,1JQ4Y@119043|Rhodobiaceae	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
WLSH2_k127_4266160_8	1205680.CAKO01000035_gene203	1.29e-78	275.0	COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,2TRGF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA	-	-	-	-	-	-	-	-	-	-	-	-	TauD
WLSH2_k127_4266160_7	795666.MW7_0585	7.649e-96	324.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_4266160_10	94624.Bpet3505	3.306e-70	249.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T21B@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_4266160_0	1218084.BBJK01000007_gene906	1.297e-258	811.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2W1P1@28216|Betaproteobacteria,1K0XN@119060|Burkholderiaceae	28216|Betaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
WLSH2_k127_4266160_11	948106.AWZT01000001_gene5085	9.216e-58	207.0	COG2080@1|root,COG2080@2|Bacteria,1PI3V@1224|Proteobacteria,2W6PI@28216|Betaproteobacteria,1KC83@119060|Burkholderiaceae	28216|Betaproteobacteria	C	[2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
WLSH2_k127_4266160_13	1218084.BBJK01000007_gene914	4.399e-40	151.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,1K1D1@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_4266160_15	1231391.AMZF01000015_gene2250	9.136e-30	121.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,3T8SB@506|Alcaligenaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_4272793_8	1236959.BAMT01000006_gene443	1.766e-93	310.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,2KKPZ@206350|Nitrosomonadales	206350|Nitrosomonadales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WLSH2_k127_4272793_7	1301098.PKB_5432	1.194e-95	318.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Histidine biosynthesis bifunctional protein HisB	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_2746,iECS88_1305.ECS88_2121,iJN746.PP_0289,iUMNK88_1353.UMNK88_2570	Hydrolase_like,IGPD,PNK3P
WLSH2_k127_4272793_2	261292.Nit79A3_1048	8.231e-136	441.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,371PJ@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH2_k127_4272793_0	1266925.JHVX01000004_gene1300	1.089e-193	613.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,372PC@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
WLSH2_k127_4272793_6	580332.Slit_0696	3.635e-106	347.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,44V3X@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
WLSH2_k127_4272793_4	1123392.AQWL01000001_gene1545	1.248e-111	367.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,1KS0M@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WLSH2_k127_4272793_9	864073.HFRIS_000695	2.767e-66	237.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VTUV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
WLSH2_k127_4272793_1	1163617.SCD_n00584	2.188e-183	581.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WLSH2_k127_4272793_11	1121004.ATVC01000003_gene482	2.299e-30	121.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
WLSH2_k127_4272793_5	1121004.ATVC01000003_gene481	2.955e-110	362.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,2KPNJ@206351|Neisseriales	206351|Neisseriales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WLSH2_k127_4272793_3	1266925.JHVX01000011_gene1525	3.56e-128	416.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,3726R@32003|Nitrosomonadales	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_4272793_12	1266925.JHVX01000011_gene1526	1.218e-19	92.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,2WB4V@28216|Betaproteobacteria,373NW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	transporter antisigma-factor antagonist STAS	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
WLSH2_k127_4272793_10	1304883.KI912532_gene1653	2.445e-53	195.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KW7C@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, auxiliary component	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
WLSH2_k127_4272793_13	640081.Dsui_1400	1.632e-13	70.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,2KWBN@206389|Rhodocyclales	206389|Rhodocyclales	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WLSH2_k127_428062_1	1317118.ATO8_16755	3.366e-75	265.0	COG1250@1|root,COG1250@2|Bacteria,1MVVD@1224|Proteobacteria,2U0T1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18612	ko00750,ko01120,map00750,map01120	-	R04524	RC00075	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WLSH2_k127_428062_0	1123072.AUDH01000025_gene360	3.535e-76	267.0	COG3181@1|root,COG3181@2|Bacteria,1P88K@1224|Proteobacteria,2TUJU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_428062_2	883080.HMPREF9697_01896	8.202e-67	241.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2TSS4@28211|Alphaproteobacteria,3JRRK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	catB	-	5.1.1.20,5.5.1.1,5.5.1.7	ko:K01856,ko:K01860,ko:K19802	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R04259,R05300,R05390,R05392,R06834,R06840,R06989,R08116,R08119,R09135,R09215,R09217,R09221,R09229,R10938	RC00903,RC01038,RC01108,RC01321,RC01356,RC01358,RC01687,RC02117,RC02448,RC02464,RC02465,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_428062_3	1380394.JADL01000016_gene415	1.412e-06	49.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2JPA1@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase	-	-	-	ko:K02031,ko:K02032,ko:K13892	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	ABC_tran,oligo_HPY
WLSH2_k127_436813_11	762376.AXYL_04566	3.113e-08	55.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VMAF@28216|Betaproteobacteria,3T2G0@506|Alcaligenaceae	28216|Betaproteobacteria	G	Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
WLSH2_k127_436813_7	1123257.AUFV01000005_gene1444	1.099e-39	154.0	COG3296@1|root,COG3296@2|Bacteria,1N4ZK@1224|Proteobacteria,1SBG4@1236|Gammaproteobacteria,1X7HM@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
WLSH2_k127_436813_3	999541.bgla_1g33290	2.696e-116	392.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria,1K2EQ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Alpha beta hydrolase	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
WLSH2_k127_436813_1	1123393.KB891316_gene1447	1.253e-219	688.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,1KS8H@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH2_k127_436813_10	265072.Mfla_0333	1.091e-28	121.0	2EDQM@1|root,337K9@2|Bacteria,1NCVD@1224|Proteobacteria,2VWUM@28216|Betaproteobacteria,2KN8Z@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_436813_0	1095769.CAHF01000006_gene1959	0.0	1284.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,47292@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WLSH2_k127_436813_9	1163617.SCD_n00850	9.139e-34	133.0	2EBKH@1|root,335KX@2|Bacteria,1NAWH@1224|Proteobacteria,2W4UC@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_436813_8	265072.Mfla_0569	1.615e-37	146.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,2KMR6@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WLSH2_k127_436813_2	1288494.EBAPG3_7780	1.498e-179	568.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,371W0@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WLSH2_k127_436813_5	1163617.SCD_n00847	2.524e-60	213.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
WLSH2_k127_436813_6	1288494.EBAPG3_7830	1.101e-57	205.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,3734R@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
WLSH2_k127_436813_4	1123392.AQWL01000005_gene2931	6.22e-73	252.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,1KRKQ@119069|Hydrogenophilales	119069|Hydrogenophilales	H	AIR synthase related protein, N-terminal domain	-	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WLSH2_k127_445170_3	1159870.KB907784_gene2611	4.278e-25	107.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,2VW3B@28216|Betaproteobacteria,3T3T6@506|Alcaligenaceae	28216|Betaproteobacteria	K	L-2,4-diaminobutyric acid acetyltransferase	ectA	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
WLSH2_k127_445170_0	257310.BB3219	3.472e-196	620.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2VI11@28216|Betaproteobacteria,3T2Y8@506|Alcaligenaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_445170_2	1437824.BN940_07416	8.055e-57	201.0	COG1917@1|root,COG1917@2|Bacteria,1RDGQ@1224|Proteobacteria,2VV68@28216|Betaproteobacteria,3T3TQ@506|Alcaligenaceae	28216|Betaproteobacteria	S	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
WLSH2_k127_445170_1	1159870.KB907784_gene2614	2.935e-116	382.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2VM24@28216|Betaproteobacteria,3T1BF@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Ectoine hydroxylase	thpD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
WLSH2_k127_445170_4	123899.JPQP01000001_gene1599	3.371e-08	58.0	COG0834@1|root,COG0834@2|Bacteria,1R26Z@1224|Proteobacteria,2VT7R@28216|Betaproteobacteria,3T269@506|Alcaligenaceae	28216|Betaproteobacteria	ET	ABC-type amino acid transport signal transduction systems periplasmic component domain	ehuB	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WLSH2_k127_4499810_4	1003200.AXXA_18972	4.822e-158	503.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,3T1U5@506|Alcaligenaceae	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WLSH2_k127_4499810_2	1288494.EBAPG3_13540	5.104e-239	745.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,372FQ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH2_k127_4499810_6	1288494.EBAPG3_13550	9.94e-126	408.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,37255@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WLSH2_k127_4499810_0	1163617.SCD_n01950	0.0	1105.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
WLSH2_k127_4499810_1	1163617.SCD_n01958	6.625e-314	986.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
WLSH2_k127_4499810_5	580332.Slit_2097	1.537e-135	444.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2VHX9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.2	ko:K01769	ko00230,map00230	-	R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	Guanylate_cyc
WLSH2_k127_4499810_3	1000565.METUNv1_00163	4.679e-165	524.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,2KUZJ@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WLSH2_k127_4499810_10	261292.Nit79A3_1887	1.244e-30	121.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,373FJ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
WLSH2_k127_4499810_7	62928.azo3565	1.839e-115	381.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,2KVNC@206389|Rhodocyclales	206389|Rhodocyclales	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WLSH2_k127_4499810_9	497321.C664_10218	1.113e-36	143.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2VU96@28216|Betaproteobacteria,2KWYZ@206389|Rhodocyclales	206389|Rhodocyclales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
WLSH2_k127_4499810_8	257310.BB3557	2.788e-83	284.0	COG1809@1|root,COG1809@2|Bacteria,1NEVX@1224|Proteobacteria,2W6JS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	(2R)-phospho-3-sulfolactate synthase (ComA)	-	-	-	-	-	-	-	-	-	-	-	-	ComA
WLSH2_k127_4606509_1	1123393.KB891328_gene507	4.033e-15	79.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria,1KS8S@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Chorismate lyase	-	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
WLSH2_k127_4606509_0	1163617.SCD_n00508	1.442e-192	609.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WLSH2_k127_4759071_6	1288494.EBAPG3_14230	4.277e-64	225.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,3720B@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_4759071_9	497321.C664_06938	5.144e-20	93.0	COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria,2KXAK@206389|Rhodocyclales	206389|Rhodocyclales	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	DUF836
WLSH2_k127_4759071_0	323848.Nmul_A1751	7.982e-318	982.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,372EW@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WLSH2_k127_4759071_1	1288494.EBAPG3_14260	2.414e-123	400.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,371PT@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
WLSH2_k127_4759071_10	261292.Nit79A3_1955	1.889e-19	92.0	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,2VWEY@28216|Betaproteobacteria,373FT@32003|Nitrosomonadales	28216|Betaproteobacteria	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
WLSH2_k127_4759071_5	391038.Bphy_0841	8.059e-74	254.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,1K0ZU@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WLSH2_k127_4759071_2	76114.ebA5540	8.413e-106	352.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,2KVT3@206389|Rhodocyclales	206389|Rhodocyclales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WLSH2_k127_4759071_4	1266925.JHVX01000002_gene1090	6.831e-89	299.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,372H0@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WLSH2_k127_4759071_3	987059.RBXJA2T_06035	5.954e-100	331.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,1KJP1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
WLSH2_k127_4759071_7	1288494.EBAPG3_14410	3.713e-41	157.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,373EI@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH2_k127_4759071_8	1112274.KI911560_gene1972	3.496e-39	148.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,2KKJB@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
WLSH2_k127_477461_0	1266925.JHVX01000002_gene851	2.017e-140	451.0	COG2159@1|root,COG2159@2|Bacteria,1PUZA@1224|Proteobacteria,2VXX6@28216|Betaproteobacteria,372U5@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
WLSH2_k127_477461_4	1123060.JONP01000024_gene2532	2.146e-67	240.0	COG2084@1|root,COG2084@2|Bacteria,1R7WF@1224|Proteobacteria,2U3AW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
WLSH2_k127_477461_2	1403819.BATR01000130_gene4600	4.47e-103	340.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_477461_3	1123073.KB899242_gene1477	1.112e-87	295.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WLSH2_k127_477461_1	1121405.dsmv_1085	6.492e-112	385.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
WLSH2_k127_477461_6	1121405.dsmv_1086	2.604e-13	82.0	2AF4E@1|root,31534@2|Bacteria,1NEPN@1224|Proteobacteria,42WGJ@68525|delta/epsilon subdivisions,2WRTJ@28221|Deltaproteobacteria,2MM2R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
WLSH2_k127_477461_5	266264.Rmet_0828	4.376e-41	159.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VK73@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_484516_3	582744.Msip34_2295	1.18e-31	128.0	2C1BX@1|root,307EB@2|Bacteria,1MY9B@1224|Proteobacteria,2VRW7@28216|Betaproteobacteria,2KNST@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_484516_0	1288494.EBAPG3_26550	1.231e-199	630.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,37287@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_484516_1	261292.Nit79A3_1750	4.626e-191	606.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,371M1@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
WLSH2_k127_484516_2	1288494.EBAPG3_26530	3.733e-57	206.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,3726P@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WLSH2_k127_4871089_2	267608.RSc0500	4.52e-58	203.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,1K2TQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WLSH2_k127_4871089_4	243233.MCA1224	4.843e-43	162.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1XFE7@135618|Methylococcales	135618|Methylococcales	S	Tol-Pal system-associated acyl-CoA thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
WLSH2_k127_4871089_0	323848.Nmul_A2717	4.062e-96	319.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,371SV@32003|Nitrosomonadales	28216|Betaproteobacteria	U	MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
WLSH2_k127_4871089_3	1163617.SCD_n00674	3.179e-49	179.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Pfam Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
WLSH2_k127_4871089_5	1288494.EBAPG3_9090	3.015e-28	124.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,2VKUS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
WLSH2_k127_4871089_1	1163617.SCD_n00676	4.075e-85	287.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WLSH2_k127_488265_2	1485544.JQKP01000002_gene1368	6.936e-57	199.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,44VKS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WLSH2_k127_488265_1	204773.HEAR0062	3.45e-84	283.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria,475WA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
WLSH2_k127_488265_0	395494.Galf_2082	4.752e-103	342.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,44V7A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WLSH2_k127_488265_3	323848.Nmul_A1989	1.856e-14	73.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,373HP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0250 family	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
WLSH2_k127_4955272_8	375286.mma_3587	2.967e-11	66.0	2EP1T@1|root,315BD@2|Bacteria,1PVCW@1224|Proteobacteria,2WB83@28216|Betaproteobacteria,4757Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4955272_9	243924.LT42_18170	3.401e-05	48.0	2EGJB@1|root,33ABH@2|Bacteria,1NI1G@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4955272_0	1095769.CAHF01000018_gene820	1.035e-290	902.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,472VX@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
WLSH2_k127_4955272_2	1207063.P24_04989	5.161e-114	382.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,2JQ7C@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_4955272_3	859657.RPSI07_1405	2.057e-102	338.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,1K20D@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the GST superfamily	gstI	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_2
WLSH2_k127_4955272_1	479434.Sthe_1507	1.043e-131	444.0	COG0477@1|root,COG2814@2|Bacteria,2G8DX@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_4955272_6	1163617.SCD_n01388	1.521e-16	85.0	COG0694@1|root,COG0694@2|Bacteria,1NHWB@1224|Proteobacteria,2VXQB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins	-	-	-	ko:K19168	-	-	-	-	ko00000,ko02048	-	-	-	-
WLSH2_k127_4955272_4	323848.Nmul_A1737	4.941e-75	263.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,372MP@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
WLSH2_k127_4955272_7	748247.AZKH_2888	6.547e-14	76.0	2EPNT@1|root,33H9E@2|Bacteria,1NI6Z@1224|Proteobacteria,2VXVE@28216|Betaproteobacteria,2KZ8W@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4936)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4936
WLSH2_k127_4955272_5	997296.PB1_13534	3.887e-28	118.0	COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,4HCA1@91061|Bacilli,1ZCCC@1386|Bacillus	91061|Bacilli	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
WLSH2_k127_4992336_4	1231391.AMZF01000050_gene1035	9.243e-16	79.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,3T4AG@506|Alcaligenaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
WLSH2_k127_4992336_5	1094715.CM001373_gene2016	2.355e-08	62.0	2APXH@1|root,31F27@2|Bacteria,1QCFC@1224|Proteobacteria,1T85P@1236|Gammaproteobacteria,1JGAF@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_4992336_3	1288494.EBAPG3_16960	2.219e-78	266.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,372TT@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WLSH2_k127_4992336_0	1163617.SCD_n01293	2.128e-244	769.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
WLSH2_k127_4992336_2	1255043.TVNIR_1377	6.757e-91	304.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,1S2B6@1236|Gammaproteobacteria,1X0E4@135613|Chromatiales	135613|Chromatiales	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH2_k127_4992336_1	1163617.SCD_n01410	1.002e-108	357.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
WLSH2_k127_504992_15	709797.CSIRO_1973	3.189e-32	127.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,3JRNY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_504992_16	631454.N177_0836	2.291e-23	102.0	COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_504992_4	1125973.JNLC01000018_gene2318	4.206e-98	331.0	COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,3JW76@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_504992_3	1038860.AXAP01000089_gene3713	2.069e-106	354.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3JWBY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
WLSH2_k127_504992_12	870187.Thini_2190	1.126e-51	197.0	COG0607@1|root,COG0607@2|Bacteria,1RHUS@1224|Proteobacteria,1S3ZV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Rhodanese	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_504992_8	1380394.JADL01000001_gene2522	8.756e-67	248.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TS3K@28211|Alphaproteobacteria,2JRPY@204441|Rhodospirillales	204441|Rhodospirillales	EH	Belongs to the TPP enzyme family	mdlC	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WLSH2_k127_504992_2	1038859.AXAU01000015_gene935	1.227e-135	441.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2UR9F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_504992_0	1038859.AXAU01000015_gene937	9.292e-229	717.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVRF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
WLSH2_k127_504992_9	865861.AZSU01000005_gene826	1.036e-66	237.0	COG1712@1|root,COG1712@2|Bacteria,1UZUW@1239|Firmicutes,24JQ3@186801|Clostridia	186801|Clostridia	S	Domain of unknown function DUF108	-	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
WLSH2_k127_504992_5	1510531.JQJJ01000002_gene4999	3.442e-91	304.0	COG0684@1|root,COG0684@2|Bacteria,1QSHP@1224|Proteobacteria,2U948@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
WLSH2_k127_504992_11	1304883.KI912532_gene3197	2.576e-56	201.0	COG5608@1|root,COG5608@2|Bacteria,1N15F@1224|Proteobacteria,2VUHP@28216|Betaproteobacteria,2KZVK@206389|Rhodocyclales	206389|Rhodocyclales	S	Water Stress and Hypersensitive response	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
WLSH2_k127_504992_13	1463841.JOIR01000011_gene2589	2.472e-40	166.0	COG0477@1|root,COG2814@2|Bacteria,2GMBQ@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_504992_17	1038859.AXAU01000010_gene1766	1.614e-07	58.0	COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria,3JX2A@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WLSH2_k127_504992_1	243231.GSU2762	1.737e-214	683.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WLSH2_k127_504992_10	1040989.AWZU01000007_gene611	3.936e-61	218.0	COG4126@1|root,COG4126@2|Bacteria,1MWVG@1224|Proteobacteria,2U0MW@28211|Alphaproteobacteria,3JS11@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Asp Glu hydantoin racemase	MA20_16560	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_504992_7	596153.Alide_3102	1.76e-80	280.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4AB79@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_504992_6	1298867.AUES01000007_gene4943	2.717e-87	298.0	COG3181@1|root,COG3181@2|Bacteria,1R9BJ@1224|Proteobacteria,2U4Z4@28211|Alphaproteobacteria,3JVRQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_5094421_11	1288494.EBAPG3_680	6.991e-59	209.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,37313@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WLSH2_k127_5094421_7	265072.Mfla_0982	1.041e-115	383.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,2KKDU@206350|Nitrosomonadales	206350|Nitrosomonadales	S	SMART transcription factor jumonji jmjC domain protein	-	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
WLSH2_k127_5094421_13	580332.Slit_2287	3.472e-23	105.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria,44WH3@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5094421_14	1454004.AW11_03946	8.339e-06	52.0	2BU41@1|root,32PCV@2|Bacteria,1PITX@1224|Proteobacteria,2W7D5@28216|Betaproteobacteria,1KR4C@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5094421_8	1163617.SCD_n01245	2.132e-97	326.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WLSH2_k127_5094421_5	640081.Dsui_1978	3.678e-135	441.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,2KUM7@206389|Rhodocyclales	206389|Rhodocyclales	M	(Lipo)protein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
WLSH2_k127_5094421_6	1288494.EBAPG3_24750	5.479e-134	437.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,371Q4@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WLSH2_k127_5094421_1	305700.B447_04252	6.71e-198	619.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,2KUIY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WLSH2_k127_5094421_0	1276756.AUEX01000009_gene1712	2.441e-213	668.0	COG0477@1|root,COG2814@2|Bacteria,1MV8D@1224|Proteobacteria,2VJFY@28216|Betaproteobacteria,4AHDT@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_5094421_12	1100720.ALKN01000007_gene2938	1.852e-31	134.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,4AEZN@80864|Comamonadaceae	28216|Betaproteobacteria	K	SMART regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
WLSH2_k127_5094421_9	1276756.AUEX01000009_gene1713	1.606e-65	233.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria,4ADSW@80864|Comamonadaceae	28216|Betaproteobacteria	T	low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WLSH2_k127_5094421_2	1276756.AUEX01000009_gene1714	1.633e-167	535.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,4AA06@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WLSH2_k127_5094421_3	391735.Veis_1293	1.576e-164	522.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,4A9KE@80864|Comamonadaceae	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WLSH2_k127_5094421_4	358220.C380_09280	1.245e-152	490.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,4AAT1@80864|Comamonadaceae	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_5094421_10	358220.C380_09285	4.33e-60	211.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,4ABXP@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH2_k127_5106648_10	1123392.AQWL01000007_gene986	1.716e-33	132.0	COG0526@1|root,COG0526@2|Bacteria,1QXHE@1224|Proteobacteria,2VWIU@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WLSH2_k127_5106648_9	1454004.AW11_01273	4.144e-46	174.0	COG1733@1|root,COG1733@2|Bacteria,1RH3S@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	ytcD	-	-	-	-	-	-	-	-	-	-	-	HxlR
WLSH2_k127_5106648_2	748247.AZKH_1458	1.443e-109	364.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,2KUUI@206389|Rhodocyclales	206389|Rhodocyclales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua5	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WLSH2_k127_5106648_3	1380394.JADL01000005_gene5415	5.879e-90	309.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TTJV@28211|Alphaproteobacteria,2JPXD@204441|Rhodospirillales	204441|Rhodospirillales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.215	ko:K22229	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01739	RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_5106648_4	999630.TUZN_0841	7.786e-86	299.0	COG1804@1|root,arCOG02304@2157|Archaea,2XPYW@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.19	ko:K07749,ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
WLSH2_k127_5106648_8	926560.KE387023_gene2369	2.916e-49	181.0	COG2050@1|root,COG2050@2|Bacteria,1WJVA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WLSH2_k127_5106648_1	543728.Vapar_5519	1.819e-123	406.0	COG4948@1|root,COG4948@2|Bacteria,1MW3F@1224|Proteobacteria,2VP7A@28216|Betaproteobacteria,4AF3H@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_5106648_12	1094508.Tsac_0220	5.08e-06	54.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,42I9E@68295|Thermoanaerobacterales	186801|Clostridia	S	Adenosylcobalamin biosynthesis, ATP cob(I)alamin adenosyltransferase, EutT PduO type	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
WLSH2_k127_5106648_6	358220.C380_04660	2.036e-76	273.0	COG3181@1|root,COG3181@2|Bacteria,1R7W8@1224|Proteobacteria,2VP6R@28216|Betaproteobacteria,4AB7J@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_5106648_5	290317.Cpha266_1987	3.532e-78	270.0	29K36@1|root,3070J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
WLSH2_k127_5106648_7	1121015.N789_03745	1.222e-70	245.0	COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria,1S6NP@1236|Gammaproteobacteria,1X666@135614|Xanthomonadales	135614|Xanthomonadales	S	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16
WLSH2_k127_5106648_0	883080.HMPREF9697_01680	4.147e-207	650.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2TSAC@28211|Alphaproteobacteria,3JS55@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH2_k127_5106648_11	93220.LV28_22275	1.877e-20	91.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,1K3K2@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH2_k127_5143326_4	257310.BB2307	3.05e-27	111.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,3T1U6@506|Alcaligenaceae	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WLSH2_k127_5143326_2	640081.Dsui_0127	7.803e-88	297.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2VHB6@28216|Betaproteobacteria,2KUMZ@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
WLSH2_k127_5143326_0	1123368.AUIS01000019_gene1225	1.978e-170	547.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1T3CM@1236|Gammaproteobacteria,2NDP9@225057|Acidithiobacillales	225057|Acidithiobacillales	L	GIY-YIG type nucleases (URI domain)	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
WLSH2_k127_5143326_3	795666.MW7_0585	2.225e-86	297.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_5143326_1	1205680.CAKO01000042_gene5324	7.769e-88	296.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2JRQS@204441|Rhodospirillales	204441|Rhodospirillales	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
WLSH2_k127_5143326_5	522306.CAP2UW1_3268	3.129e-11	70.0	2E827@1|root,332G9@2|Bacteria,1ND10@1224|Proteobacteria,2VW87@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3567)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3567
WLSH2_k127_5143326_6	1282876.BAOK01000001_gene1086	1.802e-10	63.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria,4BQ7C@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_517249_5	96561.Dole_0584	1.082e-10	65.0	2CDRQ@1|root,32RYB@2|Bacteria,1N5WB@1224|Proteobacteria,430N1@68525|delta/epsilon subdivisions,2WVK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_517249_0	1236959.BAMT01000011_gene3204	0.0	1236.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,2KM0Q@206350|Nitrosomonadales	206350|Nitrosomonadales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WLSH2_k127_517249_4	1163617.SCD_n00046	6.094e-33	130.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
WLSH2_k127_517249_2	1266925.JHVX01000003_gene558	5.513e-127	414.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,37292@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
WLSH2_k127_517249_3	1163617.SCD_n00048	3.501e-57	209.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_517249_1	1163617.SCD_n00049	9.766e-316	982.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH2_k127_5262247_5	1134413.ANNK01000087_gene226	0.0009163	43.0	COG0477@1|root,COG2814@2|Bacteria,1V1FR@1239|Firmicutes,4HGHP@91061|Bacilli,1ZGSN@1386|Bacillus	91061|Bacilli	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_5262247_0	1168059.KB899087_gene610	1.918e-206	654.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3EYTK@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
WLSH2_k127_5262247_3	983917.RGE_21700	8.555e-31	126.0	29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VT23@28216|Betaproteobacteria,1KM1I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
WLSH2_k127_5262247_2	535289.Dtpsy_3324	1.893e-75	265.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_5262247_1	1298867.AUES01000025_gene3072	2.277e-145	467.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2TWC9@28211|Alphaproteobacteria,3JVP3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_5262247_4	1005999.GLGR_0799	3.054e-16	79.0	COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,1RS00@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	3-carboxy-cis,cis-muconate cycloisomerase	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WLSH2_k127_5277533_2	292415.Tbd_2291	2.529e-91	302.0	COG4778@1|root,COG4778@2|Bacteria,1MUPB@1224|Proteobacteria,2VQ6N@28216|Betaproteobacteria	28216|Betaproteobacteria	P	phosphonate C-P lyase system protein PhnL	phnL	-	2.7.8.37	ko:K05780	ko00440,map00440	-	R10185	RC00005,RC00063	ko00000,ko00001,ko01000	-	-	-	ABC_tran
WLSH2_k127_5277533_0	292415.Tbd_2290	9.279e-167	541.0	COG3454@1|root,COG3454@2|Bacteria,1MV7H@1224|Proteobacteria,2VMPU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	phosphonate metabolism protein PhnM	phnM	-	3.6.1.63	ko:K06162	ko00440,map00440	-	R10186	RC00002	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WLSH2_k127_5277533_3	292415.Tbd_2289	8.879e-62	219.0	COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,2VSGN@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)	phnN	-	2.7.4.23	ko:K05774	ko00030,map00030	-	R06836	RC00002	ko00000,ko00001,ko01000	-	-	-	AAA_18,Guanylate_kin
WLSH2_k127_5277533_1	292415.Tbd_2288	3.783e-100	332.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2VKJK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	beta-lactamase domain protein	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
WLSH2_k127_5277533_4	395494.Galf_2754	1.321e-45	170.0	COG0697@1|root,COG0697@2|Bacteria,1PWAT@1224|Proteobacteria,2VZRR@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_5300411_0	1163617.SCD_n01470	2.629e-313	973.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
WLSH2_k127_5300411_1	582744.Msip34_0897	1.107e-95	315.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,2KKQX@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
WLSH2_k127_5343049_1	404589.Anae109_1167	3.831e-98	328.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YXVH@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
WLSH2_k127_5343049_0	76114.ebA3964	6.827e-238	748.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,2KU6W@206389|Rhodocyclales	206389|Rhodocyclales	J	ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
WLSH2_k127_5343049_2	391735.Veis_2623	2.159e-27	113.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,4ADGX@80864|Comamonadaceae	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WLSH2_k127_538758_10	1163617.SCD_n01141	1.873e-37	145.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2VWK8@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
WLSH2_k127_538758_5	62928.azo0103	5.462e-132	438.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,2VKGI@28216|Betaproteobacteria,2KW58@206389|Rhodocyclales	206389|Rhodocyclales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WLSH2_k127_538758_1	1266925.JHVX01000004_gene1144	1.906e-218	690.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,371XE@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WLSH2_k127_538758_11	1175306.GWL_08000	4.225e-27	114.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,474S8@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WLSH2_k127_538758_2	1288494.EBAPG3_13390	2.262e-176	560.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,3723Q@32003|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_538758_3	305700.B447_00255	1.848e-167	531.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,2KV71@206389|Rhodocyclales	206389|Rhodocyclales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH2_k127_538758_0	1538295.JY96_16975	3.518e-219	684.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,1KJ2B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
WLSH2_k127_538758_9	1123257.AUFV01000003_gene967	3.205e-43	160.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,1T07B@1236|Gammaproteobacteria,1X8T2@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1255
WLSH2_k127_538758_8	1123392.AQWL01000001_gene1586	1.215e-62	220.0	COG5405@1|root,COG5405@2|Bacteria,1RAFD@1224|Proteobacteria,2VMEF@28216|Betaproteobacteria,1KSWS@119069|Hydrogenophilales	119069|Hydrogenophilales	O	PFAM 20S proteasome, A and B subunits	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_538758_7	748280.NH8B_2313	2.401e-68	235.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,2KQYV@206351|Neisseriales	206351|Neisseriales	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
WLSH2_k127_538758_6	1121861.KB899934_gene478	5.897e-74	257.0	COG0607@1|root,COG4275@1|root,COG0607@2|Bacteria,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TRC3@28211|Alphaproteobacteria,2JPWH@204441|Rhodospirillales	204441|Rhodospirillales	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist,Rhodanese
WLSH2_k127_538758_4	748247.AZKH_3654	5.187e-156	497.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,2KV7A@206389|Rhodocyclales	206389|Rhodocyclales	P	Chromate Ion Transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WLSH2_k127_557484_0	1380394.JADL01000001_gene2481	3.615e-142	466.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2UQ0A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_557484_4	211586.SO_0106	7.758e-06	52.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,1RQJI@1236|Gammaproteobacteria,2Q8ZI@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Translation elongation factor	selB	GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
WLSH2_k127_557484_1	321955.AAGP01000031_gene1179	1.833e-68	244.0	COG3181@1|root,COG3181@2|Bacteria,2GJ89@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
WLSH2_k127_557484_2	1095769.CAHF01000013_gene3261	2.682e-68	239.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,4742W@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
WLSH2_k127_557484_3	1121013.P873_14330	9.35e-68	236.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,1S3X6@1236|Gammaproteobacteria,1XC92@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1415)	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
WLSH2_k127_5585446_4	1207063.P24_01946	2.654e-118	384.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JUXN@204441|Rhodospirillales	204441|Rhodospirillales	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
WLSH2_k127_5585446_15	997346.HMPREF9374_3293	1.155e-51	196.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli,27B90@186824|Thermoactinomycetaceae	91061|Bacilli	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
WLSH2_k127_5585446_0	748247.AZKH_3044	0.0	1448.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,2KUCG@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC
WLSH2_k127_5585446_11	1532557.JL37_26170	8.214e-72	250.0	COG0684@1|root,COG0684@2|Bacteria,1PIP4@1224|Proteobacteria,2WB5S@28216|Betaproteobacteria,3T7UZ@506|Alcaligenaceae	28216|Betaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
WLSH2_k127_5585446_1	795666.MW7_1725	1.858e-149	485.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNBG@28216|Betaproteobacteria,1K297@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Pfam Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
WLSH2_k127_5585446_19	1121861.KB899939_gene3785	9.246e-08	55.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,2JRHZ@204441|Rhodospirillales	204441|Rhodospirillales	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Choline_sulf_C,Sulfatase
WLSH2_k127_5585446_9	266264.Rmet_3671	1.968e-82	285.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_5585446_3	883080.HMPREF9697_02843	1.038e-122	433.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,3JW9D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	MA20_44000	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
WLSH2_k127_5585446_5	1392838.AWNM01000078_gene1135	8.811e-116	380.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,3T1ZW@506|Alcaligenaceae	28216|Betaproteobacteria	K	Transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
WLSH2_k127_5585446_13	748247.AZKH_2406	8.389e-66	229.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,2KY6G@206389|Rhodocyclales	206389|Rhodocyclales	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH2_k127_5585446_18	396588.Tgr7_0680	9.152e-25	110.0	COG1773@1|root,COG1773@2|Bacteria	2|Bacteria	C	rubredoxin	rubA	GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0071704,GO:1901575	-	-	-	-	-	-	-	-	-	-	Rubredoxin
WLSH2_k127_5585446_10	713586.KB900536_gene2775	8.645e-73	256.0	COG0428@1|root,COG0428@2|Bacteria,1MWEZ@1224|Proteobacteria,1RNXU@1236|Gammaproteobacteria,1WWUH@135613|Chromatiales	135613|Chromatiales	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
WLSH2_k127_5585446_2	1266925.JHVX01000008_gene242	2.18e-133	435.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2WGST@28216|Betaproteobacteria,372BA@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	rubB	-	1.18.1.1	ko:K05297,ko:K12265	ko00071,ko05132,map00071,map05132	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH2_k127_5585446_12	1163408.UU9_16426	7.298e-69	239.0	COG0705@1|root,COG0705@2|Bacteria,1RD88@1224|Proteobacteria,1S5NF@1236|Gammaproteobacteria,1X4YW@135614|Xanthomonadales	135614|Xanthomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WLSH2_k127_5585446_6	204773.HEAR0393	3.421e-105	350.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,2VKMF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Formate nitrite	-	-	-	ko:K02598,ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.3	-	-	Form_Nir_trans
WLSH2_k127_5585446_16	1122604.JONR01000034_gene388	2.383e-33	133.0	COG3108@1|root,COG3108@2|Bacteria,1P298@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5585446_7	880072.Desac_0814	1.563e-95	327.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,43DC6@68525|delta/epsilon subdivisions,2X8I6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5585446_20	1547437.LL06_14215	9.057e-07	61.0	2BZQB@1|root,32Y98@2|Bacteria,1R3P4@1224|Proteobacteria,2UFWD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5585446_8	1380394.JADL01000013_gene698	4.222e-88	297.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U59W@28211|Alphaproteobacteria,2JSC8@204441|Rhodospirillales	204441|Rhodospirillales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH2_k127_5585446_17	1266925.JHVX01000015_gene200	1.795e-25	113.0	COG2827@1|root,COG2827@2|Bacteria,1PI5S@1224|Proteobacteria,2W6RZ@28216|Betaproteobacteria,374GG@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	-
WLSH2_k127_5585446_14	640511.BC1002_5221	4.306e-54	192.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WLSH2_k127_5601488_4	1411123.JQNH01000001_gene3806	2.428e-18	85.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
WLSH2_k127_5601488_0	543728.Vapar_3831	4.027e-176	565.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,2VM1C@28216|Betaproteobacteria,4ABP0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dehydrogenase	-	-	1.2.1.81	ko:K15515	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
WLSH2_k127_5601488_1	713586.KB900536_gene956	6.654e-158	512.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,1WWI2@135613|Chromatiales	135613|Chromatiales	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_5601488_2	1123377.AUIV01000012_gene708	8.927e-48	177.0	2E585@1|root,3300K@2|Bacteria,1N9MI@1224|Proteobacteria,1SDGZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5630133_1	1173024.KI912148_gene3141	1.663e-24	106.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH2_k127_5630133_0	1122927.KB895417_gene3176	1.977e-65	237.0	COG0438@1|root,COG0438@2|Bacteria,1V0G0@1239|Firmicutes,4HCG7@91061|Bacilli,26ZNF@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH2_k127_5689843_1	765698.Mesci_2018	1.234e-132	440.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,43MH7@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WLSH2_k127_5689843_6	1280949.HAD_10080	2.343e-60	215.0	COG1335@1|root,COG1335@2|Bacteria,1RBT2@1224|Proteobacteria,2U6TT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
WLSH2_k127_5689843_5	1173028.ANKO01000052_gene1680	3.826e-68	239.0	COG0412@1|root,COG0412@2|Bacteria,1G5GK@1117|Cyanobacteria,1HF4X@1150|Oscillatoriales	1117|Cyanobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
WLSH2_k127_5689843_3	1472716.KBK24_0102910	1.273e-96	327.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2VV9X@28216|Betaproteobacteria,1K8N9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
WLSH2_k127_5689843_4	1268622.AVS7_03045	2.022e-72	257.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4ABD6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_5689843_0	1125973.JNLC01000010_gene1417	5.361e-221	700.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,3JZ96@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WLSH2_k127_5689843_2	709797.CSIRO_0020	6.767e-113	379.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2U0KX@28211|Alphaproteobacteria,3JUVQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WLSH2_k127_5689843_7	667632.KB890165_gene2485	4.303e-47	184.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1K035@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_5708489_1	580332.Slit_0134	5.153e-172	543.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,44VJ6@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH2_k127_5708489_0	261292.Nit79A3_0883	9.411e-213	670.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,371YV@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WLSH2_k127_5708489_2	580332.Slit_0029	1.721e-14	80.0	2DPC5@1|root,331GN@2|Bacteria,1NCRC@1224|Proteobacteria,2VVUT@28216|Betaproteobacteria,44W1H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
WLSH2_k127_5738629_1	667632.KB890220_gene2806	1.799e-140	453.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,1K1H9@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD4	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
WLSH2_k127_5738629_3	864051.BurJ1DRAFT_0250	1.284e-46	174.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2VR5U@28216|Betaproteobacteria,1KKW9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cysteine-rich motif following a subset of SET domains	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
WLSH2_k127_5738629_0	1211115.ALIQ01000078_gene4127	8.016e-144	469.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2TSSE@28211|Alphaproteobacteria,3NANS@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Malonyl-CoA decarboxylase N-terminal domain	matA	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
WLSH2_k127_5738629_2	358220.C380_15605	1.335e-93	317.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHHP@28216|Betaproteobacteria,4ABEQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_5738629_4	1502770.JQMG01000001_gene90	4.254e-39	151.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2VJB8@28216|Betaproteobacteria,2KMCB@206350|Nitrosomonadales	206350|Nitrosomonadales	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
WLSH2_k127_5752428_4	743836.AYNA01000111_gene7	2.081e-23	99.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2UC5P@28211|Alphaproteobacteria,36YPR@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
WLSH2_k127_5752428_2	713586.KB900536_gene1533	4.257e-47	174.0	COG3577@1|root,COG3577@2|Bacteria,1MY8C@1224|Proteobacteria,1SBXM@1236|Gammaproteobacteria,1X0VU@135613|Chromatiales	135613|Chromatiales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
WLSH2_k127_5752428_0	768671.ThimaDRAFT_4172	2.518e-197	621.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,1T0C6@1236|Gammaproteobacteria,1WXH4@135613|Chromatiales	135613|Chromatiales	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WLSH2_k127_5752428_1	768671.ThimaDRAFT_4173	1.11e-105	349.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
WLSH2_k127_5752428_3	243233.MCA0071	5.821e-32	127.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1XF04@135618|Methylococcales	135618|Methylococcales	S	pfam ammecr1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
WLSH2_k127_5863287_3	1380394.JADL01000001_gene2257	1.675e-68	243.0	COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,2U4JI@28211|Alphaproteobacteria,2JUE6@204441|Rhodospirillales	204441|Rhodospirillales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_5863287_6	1366050.N234_07805	5.704e-15	84.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,1K3IG@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pfam Ankyrin	arp3	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
WLSH2_k127_5863287_0	795666.MW7_2938	1.639e-184	582.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,1K3VB@119060|Burkholderiaceae	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WLSH2_k127_5863287_5	93220.LV28_17025	7.817e-62	219.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,1K2H3@119060|Burkholderiaceae	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WLSH2_k127_5863287_2	580332.Slit_2353	1.31e-69	243.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,44VSG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WLSH2_k127_5863287_1	1266925.JHVX01000003_gene537	3.074e-158	504.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,372EZ@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WLSH2_k127_5863287_4	640081.Dsui_1034	1.318e-65	228.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,2KUJ6@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
WLSH2_k127_5881182_13	264198.Reut_B4641	1.102e-55	202.0	COG3181@1|root,COG3181@2|Bacteria,1R68W@1224|Proteobacteria,2VM2X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_5881182_7	1205680.CAKO01000006_gene3368	3.972e-140	457.0	COG1454@1|root,COG1454@2|Bacteria,1RC9B@1224|Proteobacteria,2U6JQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
WLSH2_k127_5881182_4	631454.N177_1479	6.644e-172	551.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TQYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CoA binding domain	MA20_15065	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_5881182_10	631454.N177_1479	1.631e-79	274.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TQYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CoA binding domain	MA20_15065	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_5881182_3	1243664.CAVL020000045_gene2105	9.088e-185	588.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HA40@91061|Bacilli,1ZMF3@1386|Bacillus	91061|Bacilli	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
WLSH2_k127_5881182_2	631454.N177_1480	5.922e-211	666.0	COG4799@1|root,COG4799@2|Bacteria,1PFU5@1224|Proteobacteria,2UNSY@28211|Alphaproteobacteria,1JQ37@119043|Rhodobiaceae	28211|Alphaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
WLSH2_k127_5881182_1	1007105.PT7_3036	4.624e-214	676.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,3T5HE@506|Alcaligenaceae	28216|Betaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH2_k127_5881182_17	1282876.BAOK01000001_gene1988	1.193e-17	85.0	COG4770@1|root,COG4770@2|Bacteria,1NJ80@1224|Proteobacteria	1224|Proteobacteria	I	Acetyl propionyl-CoA carboxylase alpha subunit	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
WLSH2_k127_5881182_14	1366050.N234_03190	1.547e-43	171.0	COG1802@1|root,COG1802@2|Bacteria,1RBC0@1224|Proteobacteria,2VV2K@28216|Betaproteobacteria,1K1NG@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WLSH2_k127_5881182_9	207954.MED92_09051	7.099e-103	341.0	COG1024@1|root,COG1024@2|Bacteria,1MWF6@1224|Proteobacteria,1RZJJ@1236|Gammaproteobacteria,1XHUB@135619|Oceanospirillales	135619|Oceanospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH2_k127_5881182_16	1123399.AQVE01000001_gene736	4.182e-25	114.0	2DQHJ@1|root,336X1@2|Bacteria,1QYDU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5881182_8	296591.Bpro_1464	1.539e-107	357.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2VJKU@28216|Betaproteobacteria,4AB6Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WLSH2_k127_5881182_11	323848.Nmul_A2630	4.062e-69	241.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,372YC@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c, class I	cyc	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
WLSH2_k127_5881182_12	323848.Nmul_A2080	2.93e-59	211.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,372SN@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
WLSH2_k127_5881182_5	292415.Tbd_0189	2.043e-158	505.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,1KRB0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
WLSH2_k127_5881182_15	1163617.SCD_n02939	7.174e-36	140.0	COG1418@1|root,COG1418@2|Bacteria,1RH6M@1224|Proteobacteria,2VRKW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_5881182_0	1288494.EBAPG3_23410	6.215e-321	998.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,37235@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM glycosyl transferase, family 51	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
WLSH2_k127_5881182_6	1163617.SCD_n02941	3.495e-150	482.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
WLSH2_k127_6028343_5	768671.ThimaDRAFT_3399	9.215e-51	189.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,1SZQ8@1236|Gammaproteobacteria,1WZ07@135613|Chromatiales	135613|Chromatiales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_6028343_1	292415.Tbd_0518	4.382e-222	698.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,1KS6T@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Adenylosuccinate lyase C-terminal	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
WLSH2_k127_6028343_4	557598.LHK_01013	7.227e-87	291.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,2KQAQ@206351|Neisseriales	206351|Neisseriales	S	Psort location CytoplasmicMembrane, score 10.00	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
WLSH2_k127_6028343_3	323848.Nmul_A2426	4.748e-129	422.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,372X0@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH2_k127_6028343_0	1163617.SCD_n02208	1.889e-273	853.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
WLSH2_k127_6028343_6	1000565.METUNv1_00172	6.906e-33	133.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,2KWNW@206389|Rhodocyclales	206389|Rhodocyclales	U	preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
WLSH2_k127_6028343_2	1163617.SCD_n02210	3.053e-183	578.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WLSH2_k127_6028343_7	887898.HMPREF0551_1619	2.191e-32	126.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,1JZW6@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WLSH2_k127_604143_4	391008.Smal_0593	6.804e-08	55.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,1S43Y@1236|Gammaproteobacteria,1X5SW@135614|Xanthomonadales	135614|Xanthomonadales	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
WLSH2_k127_604143_3	1121937.AUHJ01000001_gene336	4.551e-08	55.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,467WF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
WLSH2_k127_604143_0	1123072.AUDH01000001_gene3188	1.439e-66	231.0	COG2391@1|root,COG2391@2|Bacteria,1R5DN@1224|Proteobacteria,2U2XY@28211|Alphaproteobacteria,2JWXH@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
WLSH2_k127_604143_1	1123072.AUDH01000001_gene3187	1.263e-57	206.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,2U4F1@28211|Alphaproteobacteria,2JWWU@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulphur transport	-	-	-	-	-	-	-	-	-	-	-	-	Sulf_transp
WLSH2_k127_604143_2	1049564.TevJSym_ad01310	9.048e-24	102.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,1S8SK@1236|Gammaproteobacteria,1J6CX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	yjcF	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
WLSH2_k127_6120737_0	323848.Nmul_A0210	8.412e-139	447.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,37240@32003|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
WLSH2_k127_6120737_2	1266925.JHVX01000016_gene176	4.976e-69	240.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,2VQ18@28216|Betaproteobacteria,372RY@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
WLSH2_k127_6120737_1	1123392.AQWL01000002_gene1930	1.734e-107	356.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,1KSW6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage system P-protein	-	-	-	-	-	-	-	-	-	-	-	-	GDC-P
WLSH2_k127_6134865_3	296591.Bpro_1731	1.177e-32	128.0	COG2207@1|root,COG2207@2|Bacteria,1R453@1224|Proteobacteria,2VNAV@28216|Betaproteobacteria,4ADBI@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
WLSH2_k127_6134865_1	138119.DSY0972	1.442e-105	365.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,261C3@186807|Peptococcaceae	186801|Clostridia	C	Succinate dehydrogenase fumarate reductase flavoprotein	-	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WLSH2_k127_6134865_4	563192.HMPREF0179_00537	2.416e-11	75.0	COG1146@1|root,COG1146@2|Bacteria,1PSAU@1224|Proteobacteria,432M2@68525|delta/epsilon subdivisions,2WST1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH2_k127_6134865_2	314271.RB2654_02824	1.269e-75	267.0	COG1073@1|root,COG1073@2|Bacteria,1N5CG@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the UPF0255 family	frsA	GO:0003674,GO:0003824,GO:0005575,GO:0006109,GO:0006629,GO:0008150,GO:0008152,GO:0009894,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0019222,GO:0043470,GO:0044238,GO:0050789,GO:0065007,GO:0071704,GO:0080090	-	ko:K11750	-	-	-	-	ko00000,ko01000	-	-	-	DUF1100
WLSH2_k127_6134865_0	1288494.EBAPG3_7550	6.52e-321	1003.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,3724V@32003|Nitrosomonadales	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
WLSH2_k127_6134865_5	1218075.BAYA01000034_gene6175	7.867e-10	67.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2WEFN@28216|Betaproteobacteria,1K2W5@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
WLSH2_k127_6196714_1	1218086.BBNB01000003_gene2395	4.865e-225	705.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria,3WXVK@544|Citrobacter	1236|Gammaproteobacteria	V	ABC-2 family transporter protein	rbbA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0042623,GO:0043021,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060187,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
WLSH2_k127_6196714_4	287.DR97_2602	4.628e-113	375.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RS3I@1236|Gammaproteobacteria,1YFBW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	yhiI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
WLSH2_k127_6196714_14	1336249.JADW01000004_gene3420	8.758e-06	48.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,4BGFP@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
WLSH2_k127_6196714_5	1380394.JADL01000011_gene3854	8.536e-98	328.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,2JSM7@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH2_k127_6196714_7	399795.CtesDRAFT_PD1163	2.869e-80	287.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,2WHP1@28216|Betaproteobacteria,4ACYE@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_6196714_9	1121861.KB899913_gene2190	1.869e-65	250.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JSUV@204441|Rhodospirillales	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_6196714_16	1274374.CBLK010000013_gene4247	0.00055	46.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26Y79@186822|Paenibacillaceae	91061|Bacilli	CO	thiol-disulfide isomerase and thioredoxins	yneN	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_6196714_13	443143.GM18_0688	7.626e-15	78.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43UYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH2_k127_6196714_15	443144.GM21_1269	1.019e-05	53.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH2_k127_6196714_11	330779.Saci_1125	2.367e-17	85.0	COG1225@1|root,arCOG00310@2157|Archaea,2XQPI@28889|Crenarchaeota	28889|Crenarchaeota	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WLSH2_k127_6196714_0	525897.Dbac_1840	2.176e-277	861.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,42TI5@68525|delta/epsilon subdivisions,2WQR8@28221|Deltaproteobacteria,2MG9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
WLSH2_k127_6196714_2	525897.Dbac_1841	9.57e-180	568.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
WLSH2_k127_6196714_3	525897.Dbac_1842	2.216e-167	531.0	COG1840@1|root,COG1840@2|Bacteria,1N9WT@1224|Proteobacteria	1224|Proteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
WLSH2_k127_6196714_12	196367.JNFG01000011_gene6041	3.365e-17	87.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
WLSH2_k127_6196714_10	1121396.KB893058_gene2565	3.044e-59	216.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,Peptidase_S9
WLSH2_k127_6196714_6	742159.HMPREF0004_4390	4.391e-87	301.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPJ4@28216|Betaproteobacteria,3T36P@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_6196714_8	330084.JNYZ01000020_gene4783	2.579e-74	272.0	COG0028@1|root,COG0028@2|Bacteria,2IBXQ@201174|Actinobacteria	2|Bacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WLSH2_k127_6219019_10	323848.Nmul_A2123	1.88e-39	151.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,3732C@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
WLSH2_k127_6219019_9	1288494.EBAPG3_10650	1.289e-42	163.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,3734S@32003|Nitrosomonadales	28216|Betaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789,ko:K14742	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
WLSH2_k127_6219019_3	1266925.JHVX01000006_gene2144	1.595e-86	293.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,37236@32003|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM Phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH2_k127_6219019_2	1288494.EBAPG3_10670	6.11e-96	317.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria,372KE@32003|Nitrosomonadales	28216|Betaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WLSH2_k127_6219019_5	323097.Nham_3401	6.934e-68	240.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,3JSS7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
WLSH2_k127_6219019_6	522306.CAP2UW1_2655	4.911e-53	194.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2VRJE@28216|Betaproteobacteria,1KQX4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
WLSH2_k127_6219019_8	395495.Lcho_3126	7.983e-43	159.0	2CWAR@1|root,32SZA@2|Bacteria,1MZQI@1224|Proteobacteria,2W41G@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6219019_11	1157708.KB907466_gene659	2.757e-23	106.0	2CH9M@1|root,332CJ@2|Bacteria,1N7TS@1224|Proteobacteria,2VX3H@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6219019_1	404380.Gbem_3523	1.291e-178	599.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,43AN8@68525|delta/epsilon subdivisions,2X62F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
WLSH2_k127_6219019_0	1120983.KB894572_gene3159	1.137e-215	680.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,1JN67@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
WLSH2_k127_6219019_12	138119.DSY0975	1.769e-16	91.0	292QR@1|root,2ZQ8I@2|Bacteria	2|Bacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
WLSH2_k127_6219019_4	138119.DSY0976	1.904e-81	282.0	COG3181@1|root,COG3181@2|Bacteria	2|Bacteria	E	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_6219019_7	397945.Aave_0591	7.359e-44	164.0	COG2207@1|root,COG2207@2|Bacteria,1R453@1224|Proteobacteria,2VNAV@28216|Betaproteobacteria,4ADBI@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
WLSH2_k127_6219741_9	1175306.GWL_26100	1.195e-08	56.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
WLSH2_k127_6219741_3	1504672.669783898	1.573e-84	289.0	COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,2VR01@28216|Betaproteobacteria,4AE2Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2063
WLSH2_k127_6219741_5	1458275.AZ34_09745	4.727e-58	209.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2VU9I@28216|Betaproteobacteria,4AEMB@80864|Comamonadaceae	28216|Betaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
WLSH2_k127_6219741_1	266265.Bxe_B0289	7.428e-151	485.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2VH3Z@28216|Betaproteobacteria,1K5DC@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH2_k127_6219741_4	314285.KT71_01925	2.332e-68	238.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1S5WI@1236|Gammaproteobacteria,1J998@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	SelR domain	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR,TAT_signal
WLSH2_k127_6219741_8	1123073.KB899241_gene1978	6.326e-21	100.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
WLSH2_k127_6219741_2	1040989.AWZU01000019_gene1886	9.936e-89	298.0	COG1011@1|root,COG1011@2|Bacteria,1MU1H@1224|Proteobacteria,2TQVC@28211|Alphaproteobacteria,3JS84@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Haloacid dehalogenase-like hydrolase	MA20_30570	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
WLSH2_k127_6219741_0	1123368.AUIS01000006_gene624	5.873e-165	529.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
WLSH2_k127_6219741_6	1266925.JHVX01000005_gene1912	2.507e-49	188.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,3735C@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WLSH2_k127_6219741_7	395494.Galf_0794	2.351e-45	173.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,44V74@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
WLSH2_k127_6231150_7	232721.Ajs_2567	6.922e-08	59.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2VHSZ@28216|Betaproteobacteria,4AANF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_6231150_1	640081.Dsui_0513	1.104e-185	602.0	COG2199@1|root,COG2199@2|Bacteria,1QTT5@1224|Proteobacteria,2VKM3@28216|Betaproteobacteria,2KY09@206389|Rhodocyclales	206389|Rhodocyclales	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
WLSH2_k127_6231150_0	1123392.AQWL01000009_gene1141	2.132e-284	887.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,1KRCR@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA synthetases class I (E and Q), anti-codon binding domain	-	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
WLSH2_k127_6231150_6	1454004.AW11_01049	4.796e-11	67.0	COG2329@1|root,COG2329@2|Bacteria,1NDM8@1224|Proteobacteria,2VXVH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
WLSH2_k127_6231150_2	251229.Chro_1416	7.376e-78	267.0	COG3340@1|root,COG3340@2|Bacteria,1G6TI@1117|Cyanobacteria,3VMJQ@52604|Pleurocapsales	1117|Cyanobacteria	E	Peptidase family S51	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S51
WLSH2_k127_6231150_5	1123504.JQKD01000024_gene312	2.872e-23	103.0	COG3181@1|root,COG3181@2|Bacteria,1R8TT@1224|Proteobacteria,2VNVF@28216|Betaproteobacteria,4AHJY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_6231150_4	1207063.P24_00090	3.961e-24	103.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2UG8Q@28211|Alphaproteobacteria,2JURB@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WLSH2_k127_6231150_3	1485544.JQKP01000001_gene973	3.235e-37	143.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,44VNG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_6246542_12	331869.BAL199_21684	1.367e-34	136.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2TU6T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
WLSH2_k127_6246542_0	234267.Acid_3075	1.28e-164	534.0	COG2079@1|root,COG2079@2|Bacteria	2|Bacteria	S	2-methylcitrate dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_6246542_6	397945.Aave_3937	2.854e-94	321.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_6246542_11	196490.AUEZ01000007_gene5133	1.273e-56	207.0	COG5285@1|root,COG5285@2|Bacteria,1R7DG@1224|Proteobacteria,2TTB2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
WLSH2_k127_6246542_5	296591.Bpro_5282	1.825e-107	355.0	COG2030@1|root,COG2030@2|Bacteria,1MUR2@1224|Proteobacteria,2VHNF@28216|Betaproteobacteria,4ABFZ@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
WLSH2_k127_6246542_4	596154.Alide2_0153	2.403e-117	385.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2VJQ2@28216|Betaproteobacteria,4A9SP@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WLSH2_k127_6246542_8	1123504.JQKD01000004_gene5109	6.329e-69	243.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2W8XT@28216|Betaproteobacteria,4AHNC@80864|Comamonadaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH2_k127_6246542_3	335543.Sfum_3501	2.611e-135	444.0	COG2271@1|root,COG2271@2|Bacteria,1QXP5@1224|Proteobacteria,43C51@68525|delta/epsilon subdivisions,2X7FD@28221|Deltaproteobacteria,2MR8I@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_6246542_1	1002672.SAR11G3_01300	4.745e-161	532.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2UBG9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_6246542_13	1123060.JONP01000009_gene2114	4.394e-28	123.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,UPF0066
WLSH2_k127_6246542_2	420662.Mpe_A1034	1.936e-141	452.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,2VJ0H@28216|Betaproteobacteria,1KJXT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
WLSH2_k127_6246542_9	1500897.JQNA01000002_gene3654	1.131e-64	238.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2VJ3Z@28216|Betaproteobacteria,1KIFW@119060|Burkholderiaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WLSH2_k127_6246542_7	1156919.QWC_14899	9.181e-70	245.0	COG1073@1|root,COG1073@2|Bacteria,1RFX9@1224|Proteobacteria,2VUIP@28216|Betaproteobacteria,3T5NK@506|Alcaligenaceae	28216|Betaproteobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
WLSH2_k127_6246542_10	640512.BC1003_6057	6.194e-63	226.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2W2C7@28216|Betaproteobacteria,1K8B9@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_N_3
WLSH2_k127_626024_8	85643.Tmz1t_2172	1.557e-99	331.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,2KVYE@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
WLSH2_k127_626024_13	1123392.AQWL01000004_gene2532	1.152e-63	227.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,1KRPS@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WLSH2_k127_626024_7	640081.Dsui_2690	8.456e-116	377.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,2KV64@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WLSH2_k127_626024_10	580332.Slit_1648	5.961e-87	290.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,44VJI@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WLSH2_k127_626024_4	582744.Msip34_1409	2.858e-124	400.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,2KKZ6@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH2_k127_626024_5	62928.azo1908	4.985e-122	402.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,2KU95@206389|Rhodocyclales	206389|Rhodocyclales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WLSH2_k127_626024_6	1131553.JIBI01000017_gene571	2.168e-121	395.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,371SG@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WLSH2_k127_626024_3	323848.Nmul_A2632	7.144e-135	434.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,371P4@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Methionine aminopeptidase	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WLSH2_k127_626024_0	1163617.SCD_n01638	9.907e-307	963.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
WLSH2_k127_626024_11	265072.Mfla_1466	1.704e-81	274.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,2KKUN@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WLSH2_k127_626024_9	1123393.KB891317_gene2281	1.928e-87	297.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,1KRB1@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine	-	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WLSH2_k127_626024_15	1163617.SCD_n01664	1.202e-61	218.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VQVA@28216|Betaproteobacteria	28216|Betaproteobacteria	F	phosphoribosyltransferase	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WLSH2_k127_626024_14	519989.ECTPHS_12993	2.776e-62	215.0	COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,1SE6E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,DrsE_2
WLSH2_k127_626024_1	1163617.SCD_n01666	4.047e-269	845.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH2_k127_626024_12	1163617.SCD_n01667	6.346e-65	235.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
WLSH2_k127_626024_2	1163617.SCD_n01668	1.338e-160	523.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
WLSH2_k127_6327927_2	1123392.AQWL01000001_gene1351	3.061e-08	54.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,1KRJ6@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Putative methyltransferase	-	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
WLSH2_k127_6327927_0	1123393.KB891316_gene1434	2.461e-156	496.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,1KS76@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
WLSH2_k127_6327927_1	1123393.KB891316_gene1435	6.911e-27	111.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria,1KTG0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH2_k127_63591_1	1230476.C207_01869	6.221e-97	325.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,3JSFK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WLSH2_k127_63591_0	1187851.A33M_3788	5.792e-113	372.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WLSH2_k127_63591_3	1121085.AUCI01000004_gene1907	9.085e-36	148.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HD0U@91061|Bacilli,1ZCY6@1386|Bacillus	91061|Bacilli	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
WLSH2_k127_63591_4	323848.Nmul_A1379	4.371e-20	95.0	COG0346@1|root,COG0346@2|Bacteria,1N7R0@1224|Proteobacteria,2VV7K@28216|Betaproteobacteria,373QD@32003|Nitrosomonadales	28216|Betaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WLSH2_k127_63591_2	1123060.JONP01000030_gene2604	1.55e-77	269.0	COG4126@1|root,COG4126@2|Bacteria,1R9KP@1224|Proteobacteria,2U1PU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	flavin adenine dinucleotide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6441507_2	1005048.CFU_1657	2.764e-27	111.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,47249@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WLSH2_k127_6441507_1	748247.AZKH_3403	6.29e-84	291.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VPAG@28216|Betaproteobacteria,2KW5W@206389|Rhodocyclales	206389|Rhodocyclales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_6441507_0	859657.RPSI07_1218	0.0	1417.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,1K1A9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH2_k127_6462550_3	640081.Dsui_1634	1.32e-30	128.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,2KW8T@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_6462550_0	62928.azo1341	6.819e-280	864.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KVB2@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
WLSH2_k127_6462550_2	760117.JN27_04155	1.185e-101	334.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,472VR@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
WLSH2_k127_6462550_5	640081.Dsui_1629	3.326e-10	62.0	COG4736@1|root,COG4736@2|Bacteria,1PUF6@1224|Proteobacteria,2VXME@28216|Betaproteobacteria,2KXN0@206389|Rhodocyclales	206389|Rhodocyclales	O	Cbb3-type cytochrome oxidase	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
WLSH2_k127_6462550_1	279714.FuraDRAFT_1094	2.398e-120	393.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KQ3Y@206351|Neisseriales	206351|Neisseriales	C	Cytochrome c oxidase, subunit	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N,OmpA
WLSH2_k127_6462550_4	452638.Pnec_1359	1.892e-18	85.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,1K5SY@119060|Burkholderiaceae	28216|Betaproteobacteria	C	iron-sulfur 4fe-4s ferredoxin transmembrane protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
WLSH2_k127_6479566_2	292415.Tbd_2288	1.918e-47	174.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2VKJK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	beta-lactamase domain protein	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
WLSH2_k127_6479566_1	395494.Galf_2752	1.749e-58	210.0	COG3709@1|root,COG3709@2|Bacteria,1RGXZ@1224|Proteobacteria,2VSGN@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)	phnN	-	2.7.4.23	ko:K05774	ko00030,map00030	-	R06836	RC00002	ko00000,ko00001,ko01000	-	-	-	AAA_18,Guanylate_kin
WLSH2_k127_6479566_0	395494.Galf_2751	2.799e-158	505.0	COG3454@1|root,COG3454@2|Bacteria,1MV7H@1224|Proteobacteria,2VMPU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	phosphonate metabolism protein PhnM	phnM	-	3.6.1.63	ko:K06162	ko00440,map00440	-	R10186	RC00002	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WLSH2_k127_6577792_2	360910.BAV2903	1.618e-33	130.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VHAW@28216|Betaproteobacteria,3T2QW@506|Alcaligenaceae	28216|Betaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	glxR	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
WLSH2_k127_6577792_1	626887.J057_08586	4.475e-48	183.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria,46AP6@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	blaB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,NUDIX
WLSH2_k127_6577792_0	247633.GP2143_02120	3.255e-88	299.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria,1J5PQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	blaB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,NUDIX
WLSH2_k127_6577792_3	301.JNHE01000019_gene4109	6.593e-19	92.0	COG2199@1|root,COG2199@2|Bacteria,1QKZ4@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_9,dCache_1
WLSH2_k127_6671377_1	1245471.PCA10_34230	3.78e-160	514.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria,1YE58@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	V	ABC transporter, ATP-binding protein	yhiH	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
WLSH2_k127_6671377_4	1123269.NX02_09210	5.1e-139	464.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,2TU4P@28211|Alphaproteobacteria,2K1I9@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH2_k127_6671377_13	1123392.AQWL01000003_gene275	4.615e-53	191.0	COG5455@1|root,COG5455@2|Bacteria,1RJ9A@1224|Proteobacteria,2VRVC@28216|Betaproteobacteria,1KT1I@119069|Hydrogenophilales	119069|Hydrogenophilales	S	response to cobalt ion	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6671377_9	1196029.ALIM01000034_gene1953	2.344e-75	263.0	COG1028@1|root,COG1028@2|Bacteria,1TPZN@1239|Firmicutes,4HBJ8@91061|Bacilli,1ZCYQ@1386|Bacillus	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	yvrD	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WLSH2_k127_6671377_6	1454004.AW11_02623	1.836e-123	401.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,1KQYT@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WLSH2_k127_6671377_8	1215092.PA6_028_01190	4.343e-87	295.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1YH76@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WLSH2_k127_6671377_11	388051.AUFE01000048_gene2421	4.585e-73	258.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VM0F@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_6671377_7	1211115.ALIQ01000007_gene1069	4.22e-88	303.0	COG0656@1|root,COG0656@2|Bacteria,1PENK@1224|Proteobacteria,2V8CZ@28211|Alphaproteobacteria,3NCS5@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_6671377_10	1366050.N234_27450	3.256e-73	248.0	COG3565@1|root,COG3565@2|Bacteria,1RD7C@1224|Proteobacteria,2VRG8@28216|Betaproteobacteria,1K76N@119060|Burkholderiaceae	28216|Betaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
WLSH2_k127_6671377_2	365046.Rta_33920	1.169e-150	481.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VH6G@28216|Betaproteobacteria,4ABRZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
WLSH2_k127_6671377_0	365046.Rta_33910	8.783e-273	856.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,4ABBZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
WLSH2_k127_6671377_17	557436.Lreu_1407	7.198e-20	97.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,3F6RF@33958|Lactobacillaceae	91061|Bacilli	L	Methyltransferase	adaB	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567,ko:K10778,ko:K13531	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
WLSH2_k127_6671377_5	1163617.SCD_n02456	6.359e-127	412.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Tyrosine recombinase xerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WLSH2_k127_6671377_15	1266925.JHVX01000006_gene2091	3.881e-35	137.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,373B3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Aldolase	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
WLSH2_k127_6671377_12	859657.RPSI07_0920	3.118e-65	229.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,1K08V@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH2_k127_6671377_3	1485544.JQKP01000002_gene1669	1.966e-143	463.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,44VK7@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WLSH2_k127_6671377_16	1288494.EBAPG3_23210	7.821e-33	127.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,373FW@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WLSH2_k127_6671377_14	1144319.PMI16_00817	3.351e-51	185.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,4746T@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
WLSH2_k127_668082_2	76114.ebA6506	4.15e-161	516.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,2KUFZ@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
WLSH2_k127_668082_14	414684.RC1_1514	5.342e-52	195.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
WLSH2_k127_668082_7	1244869.H261_01572	2.432e-91	320.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,2VCDR@28211|Alphaproteobacteria,2JU96@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_668082_10	414684.RC1_1514	3.269e-61	225.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
WLSH2_k127_668082_13	365046.Rta_27530	4.357e-53	200.0	COG2230@1|root,COG2230@2|Bacteria,1QX5S@1224|Proteobacteria,2WHKW@28216|Betaproteobacteria,4AJZM@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
WLSH2_k127_668082_11	414684.RC1_1514	2.582e-59	220.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
WLSH2_k127_668082_12	414684.RC1_1514	1.135e-57	212.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
WLSH2_k127_668082_15	414684.RC1_1514	1.042e-50	194.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2UB0B@28211|Alphaproteobacteria,2JVQE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
WLSH2_k127_668082_3	251229.Chro_0525	3.932e-139	456.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,3VINB@52604|Pleurocapsales	1117|Cyanobacteria	E	Amino acid polyamine organocation transporter, APC superfamily	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WLSH2_k127_668082_0	1163617.SCD_n00964	2.688e-299	930.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
WLSH2_k127_668082_9	580332.Slit_2462	3.66e-69	245.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,2VI53@28216|Betaproteobacteria,44VCU@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	yjcC	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
WLSH2_k127_668082_1	331869.BAL199_22262	1.845e-177	561.0	COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_668082_6	1454004.AW11_00293	7.27e-99	329.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,1KQB6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	fadB3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH2_k127_668082_4	312153.Pnuc_1369	2.297e-115	380.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI9Y@28216|Betaproteobacteria,1K1EI@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
WLSH2_k127_668082_5	1288494.EBAPG3_6510	7.333e-101	337.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,371QK@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	rbcR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
WLSH2_k127_668082_8	795666.MW7_0497	4.056e-84	287.0	COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2VM9Q@28216|Betaproteobacteria,1K4QS@119060|Burkholderiaceae	28216|Betaproteobacteria	P	membrane protein, TerC	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
WLSH2_k127_675996_2	1123392.AQWL01000001_gene1425	2.73e-60	211.0	COG3531@1|root,COG3531@2|Bacteria,1RIN9@1224|Proteobacteria,2VSP5@28216|Betaproteobacteria,1KS88@119069|Hydrogenophilales	119069|Hydrogenophilales	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
WLSH2_k127_675996_1	1207076.ALAT01000115_gene3569	3.925e-87	297.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,1RPHX@1236|Gammaproteobacteria,1YZQ1@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	ydiA	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
WLSH2_k127_675996_0	1415780.JPOG01000001_gene1607	6.033e-112	368.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,1X4C5@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH2_k127_6862782_2	153948.NAL212_2198	8.218e-113	367.0	COG2267@1|root,COG2267@2|Bacteria,1QU3E@1224|Proteobacteria,2WGMS@28216|Betaproteobacteria,3721D@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the peptidase S33 family	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
WLSH2_k127_6862782_7	1392838.AWNM01000037_gene987	1.835e-47	173.0	COG0319@1|root,COG0319@2|Bacteria,1QU0Q@1224|Proteobacteria,2VSPI@28216|Betaproteobacteria,3T7M5@506|Alcaligenaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3225)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3225
WLSH2_k127_6862782_3	1366050.N234_22440	9.908e-77	290.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP82@28216|Betaproteobacteria,1KD4A@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_6862782_0	1000565.METUNv1_00265	0.0	1039.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,2KVTV@206389|Rhodocyclales	206389|Rhodocyclales	C	Malic enzyme	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
WLSH2_k127_6862782_1	261292.Nit79A3_2114	6.396e-213	670.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,371NT@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
WLSH2_k127_6862782_8	1095769.CAHF01000006_gene1694	3.161e-28	120.0	2FEKE@1|root,346JV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_6862782_4	1260251.SPISAL_07845	3.611e-55	198.0	COG2258@1|root,COG2258@2|Bacteria,1RH4S@1224|Proteobacteria,1S6EH@1236|Gammaproteobacteria,1WZR3@135613|Chromatiales	135613|Chromatiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
WLSH2_k127_6862782_6	1175306.GWL_37710	3.294e-48	175.0	COG0745@1|root,COG0745@2|Bacteria,1N7TJ@1224|Proteobacteria,2WEAK@28216|Betaproteobacteria,47237@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	PFAM Response regulator receiver domain, Transcriptional regulatory protein, C terminal	qseB	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_6908258_4	748247.AZKH_3918	2.984e-21	102.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,2KW8G@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23
WLSH2_k127_6908258_0	159087.Daro_2263	1.026e-149	488.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,2KUNJ@206389|Rhodocyclales	206389|Rhodocyclales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WLSH2_k127_6908258_3	1198452.Jab_2c04140	1.572e-25	109.0	COG5569@1|root,COG5569@2|Bacteria,1N8CJ@1224|Proteobacteria,2VVSU@28216|Betaproteobacteria,47524@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Copper binding periplasmic protein CusF	cusF	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
WLSH2_k127_6908258_2	1454004.AW11_00231	6.886e-42	156.0	COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2VSDN@28216|Betaproteobacteria,1KQUW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
WLSH2_k127_6908258_1	204773.HEAR1583	1.235e-53	193.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VSDP@28216|Betaproteobacteria,474YT@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,CusF_Ec
WLSH2_k127_6909349_9	1131553.JIBI01000048_gene1020	1.468e-118	387.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,37209@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
WLSH2_k127_6909349_3	1163617.SCD_n02472	1.803e-177	564.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
WLSH2_k127_6909349_0	323848.Nmul_A2485	0.0	1341.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,371QF@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WLSH2_k127_6909349_10	1288494.EBAPG3_28070	1.125e-107	358.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,371UP@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
WLSH2_k127_6909349_14	522306.CAP2UW1_0563	2.539e-09	65.0	COG4701@1|root,COG4701@2|Bacteria,1NHRC@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
WLSH2_k127_6909349_6	1163617.SCD_n02478	9.254e-150	478.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
WLSH2_k127_6909349_4	1163617.SCD_n02479	1.191e-175	558.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WLSH2_k127_6909349_1	1288494.EBAPG3_28130	1.909e-221	691.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,372QQ@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WLSH2_k127_6909349_12	1123392.AQWL01000002_gene1866	4.936e-53	196.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,1KRV6@119069|Hydrogenophilales	119069|Hydrogenophilales	M	POTRA domain, FtsQ-type	-	-	-	-	-	-	-	-	-	-	-	-	FtsQ,POTRA_1
WLSH2_k127_6909349_8	497321.C664_17025	2.326e-126	411.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,2KU92@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WLSH2_k127_6909349_11	1288494.EBAPG3_28160	2.377e-106	355.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,3725K@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WLSH2_k127_6909349_2	1163617.SCD_n02484	2.741e-211	666.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH2_k127_6909349_7	85643.Tmz1t_3427	1.782e-131	445.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,2KVGS@206389|Rhodocyclales	206389|Rhodocyclales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WLSH2_k127_6909349_5	1163617.SCD_n02486	2.644e-171	546.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WLSH2_k127_6909349_13	1485544.JQKP01000002_gene1628	6.007e-51	184.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,44V6N@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH2_k127_6959425_1	1205680.CAKO01000010_gene3710	1.236e-61	216.0	COG2175@1|root,COG2175@2|Bacteria,1P6UZ@1224|Proteobacteria,2TTJB@28211|Alphaproteobacteria,2JYSV@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
WLSH2_k127_6959425_0	1040989.AWZU01000035_gene1779	4.216e-253	792.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,3JT6H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Malic enzyme, NAD binding domain	MA20_02490	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
WLSH2_k127_6959425_2	497321.C664_03350	1.758e-46	173.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria	28216|Betaproteobacteria	M	RND efflux system, outer membrane lipoprotein	oprM	-	-	ko:K18139,ko:K18903	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00698,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,1.B.17.3.3,2.A.6.2	-	-	OEP
WLSH2_k127_6966912_9	265072.Mfla_1998	5.934e-20	90.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,2KM1R@206350|Nitrosomonadales	206350|Nitrosomonadales	J	TIGRFAM phenylalanyl-tRNA synthetase, beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WLSH2_k127_6966912_3	1485544.JQKP01000010_gene829	1.143e-158	505.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,44VDW@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WLSH2_k127_6966912_7	580332.Slit_1734	6.146e-52	185.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,44VWN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WLSH2_k127_6966912_8	1163617.SCD_n01110	2.06e-22	97.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WLSH2_k127_6966912_5	580332.Slit_1736	4.849e-76	260.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,44VQU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WLSH2_k127_6966912_0	305700.B447_01031	0.0	1019.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,2KU9R@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WLSH2_k127_6966912_1	1288494.EBAPG3_28580	1.283e-241	767.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,372M8@32003|Nitrosomonadales	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WLSH2_k127_6966912_2	1123487.KB892846_gene703	7.39e-225	706.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,2KV17@206389|Rhodocyclales	206389|Rhodocyclales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
WLSH2_k127_6966912_4	265072.Mfla_0392	1.119e-103	349.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2VIB5@28216|Betaproteobacteria,2KKR6@206350|Nitrosomonadales	206350|Nitrosomonadales	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
WLSH2_k127_6966912_6	395494.Galf_0077	9.004e-55	197.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2VHD7@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
WLSH2_k127_702245_4	323848.Nmul_A1775	6.992e-126	410.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,372K7@32003|Nitrosomonadales	28216|Betaproteobacteria	C	cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
WLSH2_k127_702245_17	62928.azo3298	1.725e-13	72.0	2A8MT@1|root,30XQ7@2|Bacteria,1PJJK@1224|Proteobacteria,2WB51@28216|Betaproteobacteria,2KXIZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF2909)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2909
WLSH2_k127_702245_10	1266925.JHVX01000016_gene193	1.176e-69	244.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,372Z1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
WLSH2_k127_702245_12	1000565.METUNv1_02095	4.675e-60	213.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria,2KWU1@206389|Rhodocyclales	206389|Rhodocyclales	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_702245_6	1123392.AQWL01000002_gene2095	3.06e-110	365.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2VJ3C@28216|Betaproteobacteria,1KT07@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Cytochrome oxidase assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	COX15-CtaA
WLSH2_k127_702245_2	1131553.JIBI01000002_gene1819	2.853e-134	434.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,3724X@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
WLSH2_k127_702245_11	204773.HEAR2909	1.571e-64	227.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,473BA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Involved in biogenesis of respiratory and photosynthetic systems	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WLSH2_k127_702245_5	62928.azo3292	8.175e-119	388.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,2KUT2@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
WLSH2_k127_702245_8	1266925.JHVX01000011_gene1521	7.734e-87	298.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,3728S@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
WLSH2_k127_702245_7	1123393.KB891330_gene752	3.877e-87	303.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,1KSXN@119069|Hydrogenophilales	119069|Hydrogenophilales	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WLSH2_k127_702245_3	1266925.JHVX01000011_gene1519	6.119e-132	428.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,371WI@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WLSH2_k127_702245_0	1266925.JHVX01000011_gene1518	9.248e-171	547.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,371KY@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH2_k127_702245_1	1163617.SCD_n02636	2.44e-158	512.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH2_k127_702245_13	265072.Mfla_0736	1.008e-52	192.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,2KMSC@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
WLSH2_k127_702245_15	265072.Mfla_0737	3.285e-39	147.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,2KMQ5@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH2_k127_702245_16	85643.Tmz1t_3620	4.162e-22	96.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,2KW7T@206389|Rhodocyclales	206389|Rhodocyclales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH2_k127_702245_14	497321.C664_16138	8.542e-46	167.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,2KX13@206389|Rhodocyclales	206389|Rhodocyclales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH2_k127_702245_9	1485544.JQKP01000014_gene1883	1.285e-86	291.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,44VE9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WLSH2_k127_7060849_3	335283.Neut_1953	2.087e-110	362.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,3720Y@32003|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WLSH2_k127_7060849_7	292415.Tbd_0177	2.428e-54	193.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WLSH2_k127_7060849_2	1123487.KB892836_gene3132	8.255e-123	406.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,2KVBK@206389|Rhodocyclales	206389|Rhodocyclales	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WLSH2_k127_7060849_11	1454004.AW11_00081	4.554e-34	143.0	2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
WLSH2_k127_7060849_4	1121035.AUCH01000003_gene1242	4.374e-96	323.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,2KUJE@206389|Rhodocyclales	206389|Rhodocyclales	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WLSH2_k127_7060849_0	1485544.JQKP01000002_gene1516	6.727e-245	761.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,44VMS@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WLSH2_k127_7060849_6	511062.GU3_05695	1.726e-55	197.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1Y4EP@135624|Aeromonadales	135624|Aeromonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
WLSH2_k127_7060849_5	1163617.SCD_n02787	1.219e-58	207.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
WLSH2_k127_7060849_10	1131553.JIBI01000046_gene1594	1.729e-37	148.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,3732S@32003|Nitrosomonadales	28216|Betaproteobacteria	CO	Thioredoxin-like	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
WLSH2_k127_7060849_1	76114.ebA3571	1.991e-198	636.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,2KV4F@206389|Rhodocyclales	206389|Rhodocyclales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
WLSH2_k127_7060849_9	497321.C664_19111	2.518e-39	151.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,2KX0I@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in tolerance to divalent cations	cutA1	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
WLSH2_k127_7060849_8	1366050.N234_17265	1.426e-52	188.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,1K0SV@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
WLSH2_k127_7089763_8	323848.Nmul_A0816	2.814e-18	85.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,371YU@32003|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WLSH2_k127_7089763_2	1123367.C666_07260	2.535e-129	418.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,2KUM6@206389|Rhodocyclales	206389|Rhodocyclales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WLSH2_k127_7089763_1	323848.Nmul_A0814	2.842e-130	423.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,3724H@32003|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WLSH2_k127_7089763_4	323848.Nmul_A0813	5.13e-58	204.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,37350@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
WLSH2_k127_7089763_5	557598.LHK_00192	3.524e-34	135.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,2KRIM@206351|Neisseriales	206351|Neisseriales	E	Psort location Cytoplasmic, score	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
WLSH2_k127_7089763_7	85643.Tmz1t_0913	7.279e-25	106.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,2KX8N@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WLSH2_k127_7089763_6	1304883.KI912532_gene1673	1.619e-27	118.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KWT9@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WLSH2_k127_7089763_3	497321.C664_04762	5.165e-95	319.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,2KUWA@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WLSH2_k127_7089763_0	1266925.JHVX01000004_gene1313	2.121e-145	472.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,37267@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_7089763_9	1387312.BAUS01000002_gene413	2.477e-13	76.0	2DP14@1|root,3303I@2|Bacteria,1N7JW@1224|Proteobacteria,2VW7N@28216|Betaproteobacteria,2KN9U@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7111536_3	887062.HGR_12057	4.848e-19	88.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,4AB2X@80864|Comamonadaceae	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WLSH2_k127_7111536_2	1288494.EBAPG3_1840	6.248e-75	261.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,372XP@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WLSH2_k127_7111536_0	292415.Tbd_0868	6.672e-196	634.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJI0@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	ko:K02448	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	VWA_2
WLSH2_k127_7111536_1	765911.Thivi_2803	1.415e-124	404.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria,1X0I7@135613|Chromatiales	135613|Chromatiales	S	CbbQ/NirQ/NorQ C-terminal	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
WLSH2_k127_7156733_2	1163617.SCD_n02855	7.702e-61	216.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
WLSH2_k127_7156733_0	1095769.CAHF01000023_gene479	5.28e-170	543.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,475Y7@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WLSH2_k127_7156733_1	1097668.BYI23_C013480	2.25e-88	298.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,1K3K2@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH2_k127_7156733_4	570967.JMLV01000002_gene1590	3.025e-20	96.0	COG4392@1|root,COG4392@2|Bacteria,1NA6M@1224|Proteobacteria,2UICP@28211|Alphaproteobacteria,2JTX7@204441|Rhodospirillales	204441|Rhodospirillales	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
WLSH2_k127_7156733_3	631454.N177_3648	1.056e-27	119.0	COG1296@1|root,COG1296@2|Bacteria,1QFIN@1224|Proteobacteria,2U0SX@28211|Alphaproteobacteria,1JP0E@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	AzlC protein	MA20_36175	-	-	-	-	-	-	-	-	-	-	-	AzlC
WLSH2_k127_7196179_1	1163617.SCD_n01137	9.782e-143	455.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD	-	1.1.2.4,1.1.3.15,1.1.5.12	ko:K00102,ko:K00104,ko:K03777	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475,R00704,R11591	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
WLSH2_k127_7196179_2	1049564.TevJSym_aj00680	4.862e-121	397.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,1J5UK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0277 FAD FMN-containing dehydrogenases	glcE	GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	iETEC_1333.ETEC_3246	FAD-oxidase_C,FAD_binding_4
WLSH2_k127_7196179_0	1123368.AUIS01000005_gene483	4.127e-187	591.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,2NBWP@225057|Acidithiobacillales	225057|Acidithiobacillales	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
WLSH2_k127_7196179_3	102129.Lepto7375DRAFT_5814	1.82e-22	106.0	COG2755@1|root,COG2931@1|root,COG2755@2|Bacteria,COG2931@2|Bacteria,1G0DX@1117|Cyanobacteria,1H8AY@1150|Oscillatoriales	1117|Cyanobacteria	Q	COG2931 RTX toxins and related Ca2 -binding	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,DUF11,DUF4347,HemolysinCabind,Laminin_G_3,VCBS
WLSH2_k127_7196997_6	159087.Daro_3417	5.33e-08	54.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,2KUCM@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
WLSH2_k127_7196997_7	261292.Nit79A3_0729	0.0001533	51.0	2DRHC@1|root,33BRH@2|Bacteria,1NIPF@1224|Proteobacteria,2VXM1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	tigrfam pep-cterm	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
WLSH2_k127_7196997_5	1469245.JFBG01000027_gene1443	4.545e-34	139.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,1SF74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WLSH2_k127_7196997_1	1198452.Jab_2c02510	1.539e-63	226.0	2EMEM@1|root,33F3F@2|Bacteria,1NK08@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7196997_2	1349767.GJA_2100	8.902e-47	178.0	2DNTZ@1|root,32Z4F@2|Bacteria,1NA30@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
WLSH2_k127_7196997_0	1123392.AQWL01000004_gene2758	1.637e-134	448.0	COG0642@1|root,COG0642@2|Bacteria,1R49A@1224|Proteobacteria,2VKU5@28216|Betaproteobacteria,1KSY8@119069|Hydrogenophilales	119069|Hydrogenophilales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7196997_3	1304883.KI912532_gene1638	3.062e-45	171.0	COG2165@1|root,COG2165@2|Bacteria,1RHE1@1224|Proteobacteria,2VSJ6@28216|Betaproteobacteria,2KWRU@206389|Rhodocyclales	206389|Rhodocyclales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WLSH2_k127_7196997_4	1485544.JQKP01000001_gene1090	6.608e-35	145.0	2DNAT@1|root,32WH7@2|Bacteria,1N2AT@1224|Proteobacteria,2VV51@28216|Betaproteobacteria,44W1G@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7201923_6	582744.Msip34_0566	1.454e-15	79.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,2KKDF@206350|Nitrosomonadales	206350|Nitrosomonadales	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
WLSH2_k127_7201923_2	1485544.JQKP01000002_gene1548	3.671e-98	328.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,44VH3@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
WLSH2_k127_7201923_3	543728.Vapar_2812	7.014e-69	241.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,4AE3U@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
WLSH2_k127_7201923_5	666681.M301_0850	2.659e-16	85.0	COG5488@1|root,COG5488@2|Bacteria,1N5Z9@1224|Proteobacteria,2VU1W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2244
WLSH2_k127_7201923_1	1000565.METUNv1_02088	1.154e-149	485.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,2KV6W@206389|Rhodocyclales	206389|Rhodocyclales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3
WLSH2_k127_7201923_0	1000565.METUNv1_02089	4.399e-289	893.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,2KUWI@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WLSH2_k127_7201923_4	62928.azo3301	1.11e-67	236.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2VHRQ@28216|Betaproteobacteria,2KWGM@206389|Rhodocyclales	206389|Rhodocyclales	O	oxidase assembly	-	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
WLSH2_k127_7201923_7	402626.Rpic_0222	0.0006429	45.0	2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,2VXNC@28216|Betaproteobacteria,1KABT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2970)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2970
WLSH2_k127_7244860_0	948106.AWZT01000001_gene5084	4.986e-261	815.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,1K1D1@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_7244860_1	948106.AWZT01000001_gene5083	2.577e-96	325.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VNR6@28216|Betaproteobacteria,1K9QW@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
WLSH2_k127_7244860_2	675635.Psed_3757	7.079e-07	57.0	COG3427@1|root,COG3427@2|Bacteria,2H6GM@201174|Actinobacteria,4EBRS@85010|Pseudonocardiales	201174|Actinobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	-	-	-	-	-	-	-	-	-	COXG
WLSH2_k127_7473872_8	640081.Dsui_3156	2.383e-41	164.0	COG0730@1|root,COG0730@2|Bacteria,1RKNK@1224|Proteobacteria,2VY8V@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WLSH2_k127_7473872_0	1192124.LIG30_0441	0.0	1261.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,1K1HS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
WLSH2_k127_7473872_1	748247.AZKH_2605	2.031e-264	828.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,2KY78@206389|Rhodocyclales	28216|Betaproteobacteria	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WLSH2_k127_7473872_5	795666.MW7_1853	6.877e-103	345.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2VRYX@28216|Betaproteobacteria,1K6VH@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WLSH2_k127_7473872_2	1163617.SCD_n02802	1.066e-226	709.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria	28216|Betaproteobacteria	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
WLSH2_k127_7473872_3	1163617.SCD_n02801	1.175e-117	387.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	algZ	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
WLSH2_k127_7473872_7	580332.Slit_0260	5.898e-85	289.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2WEFP@28216|Betaproteobacteria,44V6W@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LytTr DNA-binding domain	algR	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
WLSH2_k127_7473872_9	1123393.KB891316_gene1929	6.028e-25	114.0	COG2143@1|root,COG2143@2|Bacteria,1NP6X@1224|Proteobacteria,2WGR9@28216|Betaproteobacteria,1KT3R@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7473872_4	580332.Slit_0267	1.144e-112	375.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,44V8C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
WLSH2_k127_7473872_6	1266925.JHVX01000011_gene1469	3.758e-88	298.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,371TG@32003|Nitrosomonadales	28216|Betaproteobacteria	H	uroporphyrinogen III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
WLSH2_k127_7485240_1	414684.RC1_2759	2.721e-184	585.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1Q44M@1224|Proteobacteria,2V6EC@28211|Alphaproteobacteria,2JQ16@204441|Rhodospirillales	204441|Rhodospirillales	CEH	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WLSH2_k127_7485240_0	1487953.JMKF01000022_gene2509	2.236e-216	682.0	COG0161@1|root,COG0161@2|Bacteria,1G1QE@1117|Cyanobacteria,1H9SQ@1150|Oscillatoriales	1117|Cyanobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18,2.6.1.62	ko:K00822,ko:K00833	ko00280,ko00410,ko00640,ko00780,ko01100,map00280,map00410,map00640,map00780,map01100	M00123,M00573,M00577	R00907,R03231,R04187	RC00006,RC00008,RC00062,RC00160,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH2_k127_7485240_2	251221.35211453	4.07e-154	502.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1G1ZS@1117|Cyanobacteria	1117|Cyanobacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
WLSH2_k127_7485240_4	323848.Nmul_A1746	7.33e-97	322.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,371U7@32003|Nitrosomonadales	28216|Betaproteobacteria	K	RNA polymerase sigma factor	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_7485240_6	1288494.EBAPG3_14210	9.947e-31	129.0	COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,373CP@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Anti sigma-E protein RseA, N-terminal domain	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
WLSH2_k127_7485240_5	1000565.METUNv1_00626	2.471e-73	258.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria,2KUKH@206389|Rhodocyclales	206389|Rhodocyclales	T	Sigma E regulatory protein, MucB RseB	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
WLSH2_k127_7485240_3	522306.CAP2UW1_1545	1.227e-147	474.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,1KQED@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH2_k127_7507255_2	795666.MW7_0585	5.326e-103	343.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_7507255_3	543728.Vapar_0801	8.822e-85	291.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJCY@28216|Betaproteobacteria,4ABM4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_7507255_0	1123060.JONP01000024_gene2528	1.881e-108	364.0	COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,2JY55@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WLSH2_k127_7507255_4	795666.MW7_1791	2.339e-80	279.0	COG3181@1|root,COG3181@2|Bacteria,1NTB7@1224|Proteobacteria,2W167@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_7507255_1	426355.Mrad2831_4136	3.393e-106	352.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria,1JUR3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	SMP-30 Gluconolaconase LRE domain protein	-	-	3.1.1.17	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
WLSH2_k127_7507255_5	123899.JPQP01000017_gene2309	3.948e-75	261.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPJ4@28216|Betaproteobacteria,3T36P@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_7606946_4	159087.Daro_3154	6.747e-10	63.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,2VPVN@28216|Betaproteobacteria,2KWH5@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative DNA-binding domain	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
WLSH2_k127_7606946_0	1123393.KB891316_gene2075	7.531e-159	504.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,1KST9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF692)	-	-	-	-	-	-	-	-	-	-	-	-	DUF692
WLSH2_k127_7606946_2	1288494.EBAPG3_220	2.633e-23	106.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria	1224|Proteobacteria	DTZ	COG5126 Ca2 -binding protein (EF-Hand superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
WLSH2_k127_7606946_3	1123393.KB891316_gene2074	2.293e-19	91.0	COG3767@1|root,COG3767@2|Bacteria,1PW8H@1224|Proteobacteria,2VWW9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7627931_7	1158760.AQXP01000039_gene931	6.686e-28	118.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1SMM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7627931_2	545276.KB898727_gene262	6.182e-128	414.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,1RN7C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
WLSH2_k127_7627931_5	1123368.AUIS01000007_gene2767	3.093e-29	122.0	2CJFI@1|root,32XF5@2|Bacteria,1N623@1224|Proteobacteria,1SRCG@1236|Gammaproteobacteria,2NCZV@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7627931_6	1123368.AUIS01000007_gene2768	2.589e-28	117.0	2FIAJ@1|root,34A2Z@2|Bacteria,1P28Q@1224|Proteobacteria,1SSYY@1236|Gammaproteobacteria,2ND4X@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7627931_1	936455.KI421499_gene213	1.857e-173	557.0	COG2079@1|root,COG2079@2|Bacteria,1R5CE@1224|Proteobacteria,2TUP7@28211|Alphaproteobacteria,3JW76@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_7627931_4	335283.Neut_0427	2.751e-68	244.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,37224@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase,HTH_6,SIS
WLSH2_k127_7627931_3	580332.Slit_2524	5.851e-115	374.0	COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,2VRQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
WLSH2_k127_7627931_0	580332.Slit_2525	5.506e-304	936.0	COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,2VHBN@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
WLSH2_k127_7740044_2	1123393.KB891316_gene2077	3.511e-33	128.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,1KT91@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
WLSH2_k127_7740044_1	159087.Daro_3154	1.686e-68	243.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,2VPVN@28216|Betaproteobacteria,2KWH5@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative DNA-binding domain	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
WLSH2_k127_7740044_0	1123393.KB891316_gene2075	4.011e-159	505.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2VKP0@28216|Betaproteobacteria,1KST9@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF692)	-	-	-	-	-	-	-	-	-	-	-	-	DUF692
WLSH2_k127_7740044_3	1288494.EBAPG3_220	2.607e-23	104.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria	1224|Proteobacteria	DTZ	COG5126 Ca2 -binding protein (EF-Hand superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
WLSH2_k127_7740044_4	1121035.AUCH01000017_gene2269	1.59e-11	68.0	COG3767@1|root,COG3767@2|Bacteria,1Q9CJ@1224|Proteobacteria,2WBTG@28216|Betaproteobacteria,2KXP8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7794847_3	1040989.AWZU01000024_gene6482	1.357e-114	380.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,3JR5S@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	MA20_00470	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH2_k127_7794847_14	748247.AZKH_1810	1.39e-12	76.0	2ERQA@1|root,33J9N@2|Bacteria,1NI0Z@1224|Proteobacteria,2VYZY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7794847_11	1163617.SCD_n01402	1.925e-21	96.0	2E9RY@1|root,333Y3@2|Bacteria,1NB96@1224|Proteobacteria,2VX0F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7794847_9	1380355.JNIJ01000013_gene367	3.491e-32	132.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
WLSH2_k127_7794847_10	1532557.JL37_16165	7.952e-22	100.0	COG2050@1|root,COG2050@2|Bacteria,1RGQ6@1224|Proteobacteria,2VS7Y@28216|Betaproteobacteria,3T4KT@506|Alcaligenaceae	28216|Betaproteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WLSH2_k127_7794847_15	595460.RRSWK_06191	1.171e-09	63.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
WLSH2_k127_7794847_6	1123060.JONP01000009_gene2082	3.716e-84	287.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2U6K8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	xylanase chitin deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WLSH2_k127_7794847_5	596153.Alide_3218	7.549e-90	308.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2WEY1@28216|Betaproteobacteria,4AGYW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_7794847_13	1207058.L53_01785	1.32e-12	76.0	COG4446@1|root,COG4446@2|Bacteria,1NNQ9@1224|Proteobacteria,2UNH7@28211|Alphaproteobacteria,43YHD@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
WLSH2_k127_7794847_12	419610.Mext_2496	3.326e-19	90.0	COG1555@1|root,COG1555@2|Bacteria,1N7MI@1224|Proteobacteria,2UFBA@28211|Alphaproteobacteria,1JUXT@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
WLSH2_k127_7794847_0	1163617.SCD_n01151	1.832e-247	773.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
WLSH2_k127_7794847_4	338969.Rfer_3634	5.26e-107	352.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,2VP9C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WLSH2_k127_7794847_1	1163617.SCD_n01153	8.5e-227	707.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WLSH2_k127_7794847_2	1163617.SCD_n01152	2.066e-148	478.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_7794847_7	1121106.JQKB01000006_gene1309	6.379e-56	201.0	COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,2TQSD@28211|Alphaproteobacteria,2JWRR@204441|Rhodospirillales	204441|Rhodospirillales	S	decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
WLSH2_k127_7870647_0	795666.MW7_2540	1.749e-106	355.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2VH1R@28216|Betaproteobacteria,1K2BQ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	mandelate racemase muconate lactonizing	catB	-	4.2.1.113,5.5.1.1	ko:K01856,ko:K02549	ko00130,ko00361,ko00362,ko00364,ko00623,ko01100,ko01110,ko01120,ko01220,map00130,map00361,map00362,map00364,map00623,map01100,map01110,map01120,map01220	M00116,M00568	R04031,R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01053,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_7870647_4	1449126.JQKL01000013_gene3390	8.798e-62	230.0	COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,24HV2@186801|Clostridia	186801|Clostridia	S	PFAM Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_7870647_2	572547.Amico_1318	4.054e-75	262.0	COG2513@1|root,COG2513@2|Bacteria,3TAER@508458|Synergistetes	508458|Synergistetes	G	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.32	ko:K20454	ko00760,ko01120,map00760,map01120	-	R01355	RC00286,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
WLSH2_k127_7870647_1	1121106.JQKB01000003_gene2590	1.064e-94	323.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TU4F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	FMN-dependent dehydrogenase	MA20_37755	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FMN_dh
WLSH2_k127_7870647_3	1380391.JIAS01000018_gene1049	3.902e-68	238.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,2VFXG@28211|Alphaproteobacteria,2JRH8@204441|Rhodospirillales	204441|Rhodospirillales	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WLSH2_k127_7907096_6	1163617.SCD_n02460	6.871e-42	158.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WLSH2_k127_7907096_7	1266925.JHVX01000003_gene554	1.777e-30	122.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,373G4@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WLSH2_k127_7907096_3	794903.OPIT5_26535	1.491e-96	323.0	COG0778@1|root,COG0778@2|Bacteria,46YQM@74201|Verrucomicrobia,3KA08@414999|Opitutae	414999|Opitutae	C	Nitroreductase family	-	-	1.5.1.39	ko:K19286	ko00740,ko01100,map00740,map01100	-	R05705,R05706	RC00126	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
WLSH2_k127_7907096_0	323848.Nmul_A2134	2.804e-215	676.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,371SN@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WLSH2_k127_7907096_4	1266925.JHVX01000006_gene2156	2.19e-93	314.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,371QS@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Cytochrome c assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
WLSH2_k127_7907096_2	1163617.SCD_n02464	2.379e-98	336.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	CBS domain containing protein	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WLSH2_k127_7907096_1	1454004.AW11_02801	2.434e-185	587.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,1KQMT@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WLSH2_k127_7907096_5	85643.Tmz1t_1173	3.792e-69	241.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,2KVU7@206389|Rhodocyclales	206389|Rhodocyclales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WLSH2_k127_7933495_4	1095769.CAHF01000013_gene3233	5.271e-16	83.0	COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,PEGA
WLSH2_k127_7933495_3	159087.Daro_0439	4.171e-27	115.0	COG3063@1|root,COG3063@2|Bacteria,1PUFS@1224|Proteobacteria,2WATM@28216|Betaproteobacteria,2KZFJ@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_7933495_1	395494.Galf_1181	4.084e-109	366.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
WLSH2_k127_7933495_0	420324.KI912029_gene269	1.75e-133	434.0	COG4948@1|root,COG4948@2|Bacteria,1R9J6@1224|Proteobacteria,2TVSM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_7933495_2	1163617.SCD_n02027	1.01e-82	279.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase 20 kDa subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
WLSH2_k127_7936516_2	396588.Tgr7_2256	1.066e-62	224.0	COG1249@1|root,COG1249@2|Bacteria,1RB5F@1224|Proteobacteria,1S51N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	lpdA_2	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WLSH2_k127_7936516_3	1095769.CAHF01000011_gene2164	1.753e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VSEK@28216|Betaproteobacteria,474CT@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Sigma-70, region 4	rpoE8	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH2_k127_7936516_1	1163617.SCD_n00185	6.877e-81	278.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	prtR	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WLSH2_k127_7936516_0	1163617.SCD_n00173	6.079e-180	575.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WLSH2_k127_7936516_4	1163617.SCD_n02565	1.851e-38	150.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WLSH2_k127_7942573_9	292415.Tbd_0981	2.39e-15	85.0	COG3103@1|root,COG3103@2|Bacteria,1N6AX@1224|Proteobacteria,2VVME@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4
WLSH2_k127_7942573_2	93220.LV28_23310	1.315e-95	317.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,1K260@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WLSH2_k127_7942573_7	472759.Nhal_0059	8.978e-30	122.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,1S90Z@1236|Gammaproteobacteria,1X1FH@135613|Chromatiales	135613|Chromatiales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WLSH2_k127_7942573_6	76114.ebA4872	4.057e-31	130.0	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,2VU50@28216|Betaproteobacteria,2KWXY@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
WLSH2_k127_7942573_1	1123368.AUIS01000031_gene1420	7.365e-206	657.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,2NE68@225057|Acidithiobacillales	225057|Acidithiobacillales	P	STAS domain	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WLSH2_k127_7942573_0	1163617.SCD_n02021	2.41e-242	771.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
WLSH2_k127_7942573_8	1123487.KB892841_gene4269	3.327e-29	127.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,2KW8T@206389|Rhodocyclales	206389|Rhodocyclales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_7942573_3	667632.KB890167_gene1605	4.48e-71	247.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,1K1TA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
WLSH2_k127_7942573_4	396588.Tgr7_1578	4.963e-69	247.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,1RMV8@1236|Gammaproteobacteria,1WZG8@135613|Chromatiales	135613|Chromatiales	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WLSH2_k127_7942573_5	887898.HMPREF0551_1669	1.052e-33	137.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,2VX3A@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WLSH2_k127_7942573_10	1123487.KB892836_gene3200	1.333e-08	56.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,2KU9M@206389|Rhodocyclales	206389|Rhodocyclales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WLSH2_k127_794902_12	339670.Bamb_6152	2.647e-79	272.0	COG1633@1|root,COG1633@2|Bacteria,1MXX8@1224|Proteobacteria,2VI3H@28216|Betaproteobacteria,1K0A1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_794902_0	1000565.METUNv1_03391	3.893e-219	691.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2VHTR@28216|Betaproteobacteria,2KUFH@206389|Rhodocyclales	206389|Rhodocyclales	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
WLSH2_k127_794902_21	1390370.O203_06925	1.315e-12	69.0	COG4338@1|root,COG4338@2|Bacteria,1NGIS@1224|Proteobacteria,1SGEQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2256
WLSH2_k127_794902_11	62928.azo3308	1.904e-80	278.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,2KW35@206389|Rhodocyclales	206389|Rhodocyclales	K	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WLSH2_k127_794902_5	1123487.KB892864_gene2223	2e-100	333.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,2KVNT@206389|Rhodocyclales	206389|Rhodocyclales	S	Converts GTP to 7,8-dihydroneopterin triphosphate	-	-	3.5.4.16	ko:K01495,ko:K09007	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
WLSH2_k127_794902_1	62928.azo3309	1.689e-170	545.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,2KVDS@206389|Rhodocyclales	206389|Rhodocyclales	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WLSH2_k127_794902_10	522306.CAP2UW1_3958	1.777e-83	295.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,1KQN0@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
WLSH2_k127_794902_3	626418.bglu_2g09120	1.068e-132	437.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,1K0B2@119060|Burkholderiaceae	28216|Betaproteobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
WLSH2_k127_794902_20	1121116.KB894765_gene1068	9.938e-18	90.0	COG3572@1|root,COG3572@2|Bacteria,1N0R0@1224|Proteobacteria,2VUCP@28216|Betaproteobacteria,4AEYP@80864|Comamonadaceae	28216|Betaproteobacteria	H	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
WLSH2_k127_794902_6	1454004.AW11_02103	2.022e-97	335.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2VI47@28216|Betaproteobacteria,1KQMU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
WLSH2_k127_794902_13	85643.Tmz1t_1058	3.159e-77	262.0	2ANPA@1|root,31DNS@2|Bacteria,1RHTE@1224|Proteobacteria,2VRS4@28216|Betaproteobacteria,2KWF5@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3833
WLSH2_k127_794902_8	1348657.M622_03955	1.399e-90	306.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,2VH63@28216|Betaproteobacteria,2KW32@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WLSH2_k127_794902_16	614083.AWQR01000009_gene721	2.623e-42	166.0	COG3631@1|root,COG3631@2|Bacteria,1MZS5@1224|Proteobacteria,2VSD2@28216|Betaproteobacteria,4AJYT@80864|Comamonadaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
WLSH2_k127_794902_14	1163617.SCD_n02503	6.692e-59	209.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM transport-associated	-	-	-	-	-	-	-	-	-	-	-	-	BON
WLSH2_k127_794902_9	1163617.SCD_n02502	9.865e-89	298.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WLSH2_k127_794902_18	1288494.EBAPG3_5290	4.528e-33	134.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,373I0@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
WLSH2_k127_794902_19	1131553.JIBI01000013_gene916	4.215e-31	129.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,2VSUT@28216|Betaproteobacteria,372NN@32003|Nitrosomonadales	28216|Betaproteobacteria	M	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
WLSH2_k127_794902_22	1234364.AMSF01000001_gene2388	6.249e-11	70.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1X4TB@135614|Xanthomonadales	135614|Xanthomonadales	M	(Lipo)protein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
WLSH2_k127_794902_7	1163617.SCD_n02499	5.208e-91	308.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WLSH2_k127_794902_2	265072.Mfla_2280	7.612e-158	506.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,2KKH8@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WLSH2_k127_794902_17	1380394.JADL01000001_gene2870	8.083e-41	166.0	COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2U7C6@28211|Alphaproteobacteria,2JSNY@204441|Rhodospirillales	204441|Rhodospirillales	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	chaC	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
WLSH2_k127_794902_23	1111728.ATYS01000013_gene4926	3.557e-10	68.0	2E9J1@1|root,333RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_794902_15	580332.Slit_2728	1.603e-53	193.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,44VXJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WLSH2_k127_794902_4	1485544.JQKP01000002_gene1634	6.785e-112	369.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,44VNN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WLSH2_k127_7976699_2	1158182.KB905020_gene2168	3.9e-17	81.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1WW94@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH2_k127_7976699_1	323261.Noc_1573	8.736e-45	168.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH2_k127_7976699_0	243233.MCA0195	7.639e-61	212.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1XE7S@135618|Methylococcales	135618|Methylococcales	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
WLSH2_k127_7980607_4	762376.AXYL_04773	1.605e-35	137.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2VKB0@28216|Betaproteobacteria,3T2RR@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WLSH2_k127_7980607_2	1408254.T458_26085	1.582e-80	279.0	COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,4HGQE@91061|Bacilli,275PT@186822|Paenibacillaceae	91061|Bacilli	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
WLSH2_k127_7980607_0	1288494.EBAPG3_4570	7.035e-111	364.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,371MD@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WLSH2_k127_7980607_1	1163617.SCD_n01118	6.387e-88	297.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WLSH2_k127_7980607_3	582744.Msip34_0985	4.118e-47	180.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,2KKPX@206350|Nitrosomonadales	206350|Nitrosomonadales	DM	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
WLSH2_k127_8020528_3	1122604.JONR01000009_gene2310	1.432e-28	126.0	COG2208@1|root,COG4252@1|root,COG2208@2|Bacteria,COG4252@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1X49K@135614|Xanthomonadales	135614|Xanthomonadales	KT	methyl-accepting chemotaxis protein	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,HATPase_c_2,SpoIIE,dCache_1
WLSH2_k127_8020528_2	1122604.JONR01000009_gene2309	1.247e-119	392.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WLSH2_k127_8020528_4	1122604.JONR01000009_gene2308	9.332e-23	102.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,1SHX0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
WLSH2_k127_8020528_1	443598.AUFA01000095_gene6164	1.181e-144	469.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,3K2UT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WLSH2_k127_8020528_0	1532558.JL39_17070	1.15e-178	584.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4B7Q0@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WLSH2_k127_8030246_2	266264.Rmet_3424	1.602e-06	51.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,1K982@119060|Burkholderiaceae	28216|Betaproteobacteria	C	cytochrome C	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
WLSH2_k127_8030246_0	1288494.EBAPG3_12740	2.344e-89	314.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,3722S@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Tetratricopeptide repeat	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
WLSH2_k127_8030246_1	62928.azo3928	3.085e-33	131.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,2KX2W@206389|Rhodocyclales	206389|Rhodocyclales	P	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
WLSH2_k127_8031913_12	762376.AXYL_02487	3.094e-08	61.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJ08@28216|Betaproteobacteria,3T5HZ@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_8031913_9	1125973.JNLC01000011_gene592	1.367e-64	235.0	COG0673@1|root,COG0673@2|Bacteria,1QSNV@1224|Proteobacteria,2TUMB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WLSH2_k127_8031913_7	94624.Bpet3123	1.119e-78	274.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJH2@28216|Betaproteobacteria,3T55M@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_8031913_11	1424334.W822_00750	5.972e-19	88.0	2BZD4@1|root,332J5@2|Bacteria,1RC8E@1224|Proteobacteria,2W1PD@28216|Betaproteobacteria,3T7GC@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8031913_10	196490.AUEZ01000043_gene6927	1.128e-25	115.0	2AF3S@1|root,3152G@2|Bacteria,1PV19@1224|Proteobacteria,2V4HP@28211|Alphaproteobacteria,3K5ND@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8031913_2	1366050.N234_23870	3.539e-170	541.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2VS4Y@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8031913_8	331869.BAL199_30022	1.794e-66	236.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2U2FY@28211|Alphaproteobacteria,4BT8B@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
WLSH2_k127_8031913_6	264198.Reut_B3664	3.685e-91	316.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_8031913_1	1424334.W822_02425	1.845e-179	581.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2VHE3@28216|Betaproteobacteria,3T3A1@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
WLSH2_k127_8031913_4	1304877.KI519401_gene53	2.909e-114	380.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria,3JTRB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
WLSH2_k127_8031913_0	216591.BCAM0962	8.368e-189	602.0	COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,2VH7T@28216|Betaproteobacteria,1K4ZW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	2-methylcitrate dehydratase	prpD	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
WLSH2_k127_8031913_5	375286.mma_3084	1.614e-107	354.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VMYS@28216|Betaproteobacteria,476C1@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
WLSH2_k127_8031913_3	316058.RPB_2837	1.167e-122	397.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2U275@28211|Alphaproteobacteria,3JRFE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
WLSH2_k127_8178572_0	748247.AZKH_1684	1.562e-141	458.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,2KVSS@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
WLSH2_k127_8178572_1	713587.THITH_06395	3.874e-13	78.0	COG0500@1|root,COG4797@1|root,COG0500@2|Bacteria,COG4797@2|Bacteria,1MX2X@1224|Proteobacteria,1S6G8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Predicted methyltransferase regulatory domain	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg
WLSH2_k127_8334740_4	1121035.AUCH01000012_gene2986	5.952e-28	113.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,2KUUC@206389|Rhodocyclales	206389|Rhodocyclales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
WLSH2_k127_8334740_2	1288494.EBAPG3_2480	3.404e-56	199.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,3734V@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
WLSH2_k127_8334740_1	557598.LHK_00165	4.158e-112	365.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,2KQ47@206351|Neisseriales	206351|Neisseriales	T	Transcriptional regulatory protein, C terminal	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_8334740_0	1163617.SCD_n00282	1.438e-144	471.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
WLSH2_k127_8334740_3	497321.C664_13929	5.13e-45	166.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,2KWXK@206389|Rhodocyclales	206389|Rhodocyclales	FG	Histidine triad (HIT)	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WLSH2_k127_8352169_2	1163617.SCD_n00750	2.505e-97	322.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WLSH2_k127_8352169_0	748247.AZKH_1222	2.215e-142	475.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,2KURK@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	dfp	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WLSH2_k127_8352169_4	1500894.JQNN01000001_gene2634	6.942e-75	254.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,4744K@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WLSH2_k127_8352169_6	1121035.AUCH01000019_gene2897	2.953e-30	125.0	COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,2VTXE@28216|Betaproteobacteria,2KX1I@206389|Rhodocyclales	206389|Rhodocyclales	S	cobalamin (vitamin B12) biosynthesis CbiX protein	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
WLSH2_k127_8352169_5	522306.CAP2UW1_0290	1.198e-45	169.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,1KQUI@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
WLSH2_k127_8352169_1	420662.Mpe_A2481	1.892e-110	360.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,1KK0G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1,3.1.11.6	ko:K03601,ko:K04564	ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Sod_Fe_C,Sod_Fe_N
WLSH2_k127_8352169_3	312153.Pnuc_1384	6.51e-75	262.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2VRTS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
WLSH2_k127_8352169_7	1304883.KI912532_gene1726	1.659e-25	110.0	COG0547@1|root,COG0547@2|Bacteria,1QJ8Q@1224|Proteobacteria,2VH2D@28216|Betaproteobacteria,2KVGU@206389|Rhodocyclales	206389|Rhodocyclales	E	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3
WLSH2_k127_838921_1	748247.AZKH_4347	6.214e-136	439.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,2KUV3@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WLSH2_k127_838921_2	1392838.AWNM01000018_gene3438	8.793e-90	308.0	COG0500@1|root,COG0500@2|Bacteria,1QU8V@1224|Proteobacteria,2WGJ7@28216|Betaproteobacteria,3T9HQ@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Histone methylation protein DOT1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
WLSH2_k127_838921_0	1038858.AXBA01000011_gene1454	1.027e-249	781.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the UbiD family	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
WLSH2_k127_838921_4	388051.AUFE01000004_gene962	2.417e-30	125.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,1K8M5@119060|Burkholderiaceae	28216|Betaproteobacteria	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_838921_3	795666.MW7_0585	1.481e-36	142.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_8422900_4	1049564.TevJSym_bb00040	1.806e-96	334.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH2_k127_8422900_1	1049564.TevJSym_bb00050	1.921e-222	709.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WLSH2_k127_8422900_0	1187851.A33M_4208	5.123e-241	753.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum	28211|Alphaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
WLSH2_k127_8422900_2	1187851.A33M_4207	3.194e-152	485.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	gltA	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2
WLSH2_k127_8422900_7	204773.HEAR1730	1.408e-58	219.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2VSHT@28216|Betaproteobacteria,474EC@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
WLSH2_k127_8422900_6	296591.Bpro_4776	4.669e-66	229.0	2BVFD@1|root,32QUS@2|Bacteria,1RHF0@1224|Proteobacteria,2VT3V@28216|Betaproteobacteria,4AHPM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
WLSH2_k127_8422900_12	1245471.PCA10_54260	4.023e-08	57.0	COG2928@1|root,COG2928@2|Bacteria,1RK8I@1224|Proteobacteria,1S53Q@1236|Gammaproteobacteria,1YFD1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
WLSH2_k127_8422900_8	857087.Metme_4403	6.99e-49	179.0	29W5V@1|root,30HQZ@2|Bacteria,1RFZX@1224|Proteobacteria,1S4QF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184,YdjM
WLSH2_k127_8422900_5	1300345.LF41_1123	2.792e-74	256.0	COG5395@1|root,COG5395@2|Bacteria,1REYE@1224|Proteobacteria,1S5R8@1236|Gammaproteobacteria,1XBEU@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2306
WLSH2_k127_8422900_3	1205680.CAKO01000007_gene4355	1.296e-113	372.0	COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WLSH2_k127_8422900_9	555779.Dthio_PD3202	1.424e-44	164.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WRF4@28221|Deltaproteobacteria,2MD69@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WLSH2_k127_8422900_10	933262.AXAM01000171_gene926	5.339e-42	155.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42UHK@68525|delta/epsilon subdivisions,2WQDH@28221|Deltaproteobacteria,2MPR9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
WLSH2_k127_8422900_11	1197906.CAJQ02000044_gene1817	8.049e-40	148.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TR5N@28211|Alphaproteobacteria,3JR6B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	MA20_04440	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
WLSH2_k127_8455887_3	396588.Tgr7_1071	9.958e-33	132.0	COG3396@1|root,COG3396@2|Bacteria,1NJ4Y@1224|Proteobacteria,1SGSK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
WLSH2_k127_8455887_2	3988.XP_002536083.1	1.564e-84	294.0	COG1131@1|root,KOG0059@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH2_k127_8455887_0	1121035.AUCH01000003_gene1190	3.916e-157	509.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria,2KV5E@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH2_k127_8455887_1	1502770.JQMG01000001_gene1014	1.2e-122	400.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VMD2@28216|Betaproteobacteria,2KKBN@206350|Nitrosomonadales	206350|Nitrosomonadales	U	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,SPOR
WLSH2_k127_856875_8	1157640.AQWO01000036_gene3056	4.952e-18	88.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WLSH2_k127_856875_3	420662.Mpe_A1716	2.413e-159	510.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,2VMK4@28216|Betaproteobacteria,1KKKP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WLSH2_k127_856875_0	365046.Rta_19130	7.331e-260	804.0	COG4948@1|root,COG4948@2|Bacteria,1NAKW@1224|Proteobacteria,2VIQ3@28216|Betaproteobacteria,4ABQ8@80864|Comamonadaceae	28216|Betaproteobacteria	M	mandelate racemase muconate lactonizing	gudD	-	4.2.1.40	ko:K01706	ko00053,ko01100,map00053,map01100	-	R02752,R08056	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WLSH2_k127_856875_5	94122.Shewana3_2920	3.234e-54	198.0	2DMU5@1|root,32TQ2@2|Bacteria,1N4J1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_856875_7	864051.BurJ1DRAFT_1862	2.295e-23	100.0	COG1598@1|root,COG1598@2|Bacteria,1NBIX@1224|Proteobacteria,2VWQR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
WLSH2_k127_856875_4	1005395.CSV86_29062	1.234e-54	196.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,1S3CW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
WLSH2_k127_856875_6	390235.PputW619_4623	2.516e-25	106.0	COG4456@1|root,COG4456@2|Bacteria,1QNNK@1224|Proteobacteria,1TM96@1236|Gammaproteobacteria,1YZ9H@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
WLSH2_k127_856875_1	1100720.ALKN01000045_gene112	2.207e-187	591.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria,4AAI2@80864|Comamonadaceae	28216|Betaproteobacteria	G	glucose sorbosone	yliI	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
WLSH2_k127_856875_2	153948.NAL212_0605	1.859e-161	520.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,372K8@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH2_k127_8572074_2	795666.MW7_2512	3.19e-75	262.0	COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2VNXU@28216|Betaproteobacteria,1K116@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WLSH2_k127_8572074_1	713586.KB900536_gene377	7.354e-106	355.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,1T1T1@1236|Gammaproteobacteria,1X2QZ@135613|Chromatiales	135613|Chromatiales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH2_k127_8572074_0	1223521.BBJX01000006_gene1787	1.264e-113	384.0	COG2199@1|root,COG2199@2|Bacteria,1QKZ4@1224|Proteobacteria,2WHT2@28216|Betaproteobacteria,4AJRQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_9,dCache_1
WLSH2_k127_8588878_6	713587.THITH_08510	6.737e-24	104.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RZZ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	VPA0017	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH2_k127_8588878_3	713586.KB900536_gene562	9.561e-102	336.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1S4GN@1236|Gammaproteobacteria,1X2D0@135613|Chromatiales	135613|Chromatiales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH2_k127_8588878_4	215803.DB30_6542	4.941e-70	246.0	COG0500@1|root,COG2226@2|Bacteria,1RC36@1224|Proteobacteria,42UDA@68525|delta/epsilon subdivisions,2WQHW@28221|Deltaproteobacteria,2YV8X@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
WLSH2_k127_8588878_5	1379270.AUXF01000002_gene1105	3.867e-24	110.0	COG1416@1|root,COG1416@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
WLSH2_k127_8588878_7	1301098.PKB_2326	3.389e-10	69.0	2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,1SEPF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8588878_2	1163617.SCD_n01435	2.324e-106	350.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI0K@28216|Betaproteobacteria	28216|Betaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_8588878_1	1163617.SCD_n01434	2.674e-136	451.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1MUAK@1224|Proteobacteria,2WGJC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WLSH2_k127_8588878_0	338969.Rfer_3651	1.791e-139	450.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,4AC8M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_863782_6	748280.NH8B_0309	3.15e-16	88.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,2KRFQ@206351|Neisseriales	206351|Neisseriales	FG	Histidine triad domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WLSH2_k127_863782_3	203124.Tery_0530	2.438e-63	237.0	COG2866@1|root,COG2866@2|Bacteria,1GQSZ@1117|Cyanobacteria	1117|Cyanobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
WLSH2_k127_863782_7	292415.Tbd_1978	8.375e-12	78.0	2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,2VSBD@28216|Betaproteobacteria,1KS9M@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_863782_0	1163617.SCD_n00279	0.0	1856.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
WLSH2_k127_863782_4	1163617.SCD_n00278	8.556e-50	181.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH2_k127_863782_2	1430440.MGMSRv2_3490	1.614e-72	250.0	COG2227@1|root,COG2227@2|Bacteria,1QYVF@1224|Proteobacteria,2TZ70@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_863782_1	375286.mma_1296	6.876e-124	404.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2VHG8@28216|Betaproteobacteria,472KK@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
WLSH2_k127_863782_5	314278.NB231_02813	2.693e-31	126.0	2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,1SCKY@1236|Gammaproteobacteria,1WZI2@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WLSH2_k127_8742393_1	713586.KB900536_gene2177	5.283e-16	78.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1SZC2@1236|Gammaproteobacteria,1X2EH@135613|Chromatiales	135613|Chromatiales	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
WLSH2_k127_8742393_0	626887.J057_05046	9.272e-202	635.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,4641G@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WLSH2_k127_8761789_3	1120999.JONM01000001_gene1306	2.347e-236	740.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,2KPQ2@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
WLSH2_k127_8761789_20	323848.Nmul_A1201	1.019e-22	100.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,373KW@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
WLSH2_k127_8761789_17	640081.Dsui_2674	6.307e-52	186.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,2KW7M@206389|Rhodocyclales	206389|Rhodocyclales	I	Oligoketide cyclase lipid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
WLSH2_k127_8761789_13	1288494.EBAPG3_12700	1.734e-72	246.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,37321@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WLSH2_k127_8761789_21	1408444.JHYC01000013_gene2473	6.785e-20	94.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8761789_14	1163617.SCD_n01709	1.36e-67	232.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VRPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
WLSH2_k127_8761789_1	261292.Nit79A3_1591	0.0	1077.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,372MQ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WLSH2_k127_8761789_19	292415.Tbd_0694	2.125e-37	141.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,1KTA2@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal_S15	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WLSH2_k127_8761789_10	497321.C664_12325	2.593e-82	289.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,2KVRT@206389|Rhodocyclales	206389|Rhodocyclales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
WLSH2_k127_8761789_18	153948.NAL212_0878	1.099e-39	151.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,373CA@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WLSH2_k127_8761789_2	864073.HFRIS_015466	8.012e-318	993.0	COG3276@1|root,COG3276@2|Bacteria,1R1RH@1224|Proteobacteria,2WI4Y@28216|Betaproteobacteria,4794B@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
WLSH2_k127_8761789_4	1288494.EBAPG3_22420	1.409e-229	722.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,372CV@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
WLSH2_k127_8761789_15	1288494.EBAPG3_22410	7.659e-58	203.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,37338@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
WLSH2_k127_8761789_12	243265.plu4374	9.881e-80	271.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WLSH2_k127_8761789_16	292415.Tbd_0830	1.238e-52	194.0	COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,2VUGI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	-	-	ko:K13053,ko:K14160	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	SulA
WLSH2_k127_8761789_8	292415.Tbd_0829	1.088e-95	331.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2VIKH@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
WLSH2_k127_8761789_0	522306.CAP2UW1_2887	0.0	1248.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,1KR7N@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH2_k127_8761789_5	1163617.SCD_n01478	4.837e-220	686.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WLSH2_k127_8761789_9	261292.Nit79A3_3414	3.107e-89	312.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,3729G@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
WLSH2_k127_8761789_7	1485544.JQKP01000003_gene137	1.536e-98	329.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,44VHP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DNA polymerase alpha chain like domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
WLSH2_k127_8761789_11	1000565.METUNv1_02594	1.142e-80	273.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2VKQH@28216|Betaproteobacteria,2KW5S@206389|Rhodocyclales	206389|Rhodocyclales	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
WLSH2_k127_8761789_6	497321.C664_10273	1.473e-159	516.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,2KVA7@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WLSH2_k127_8761789_23	1007105.PT7_2690	1.044e-11	67.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,2VH3U@28216|Betaproteobacteria,3T2FH@506|Alcaligenaceae	28216|Betaproteobacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WLSH2_k127_8763848_5	1869.MB27_34990	1.344e-12	69.0	COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4D95H@85008|Micromonosporales	201174|Actinobacteria	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH2_k127_8763848_0	123899.JPQP01000022_gene3425	0.0	2449.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,3T1BB@506|Alcaligenaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH2_k127_8763848_6	1397528.Q671_13105	0.0005153	50.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META
WLSH2_k127_8763848_1	1123073.KB899244_gene444	1.999e-105	349.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RS05@1236|Gammaproteobacteria,1X3XC@135614|Xanthomonadales	135614|Xanthomonadales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WLSH2_k127_8763848_2	292.DM42_2500	1.013e-83	282.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2VIXW@28216|Betaproteobacteria,1JZMU@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Hemerythrin,PNP_phzG_C,Putative_PNPOx
WLSH2_k127_8763848_3	977880.RALTA_A1300	7.683e-59	218.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2VMQB@28216|Betaproteobacteria,1K049@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	Drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_8763848_4	1095769.CAHF01000013_gene3301	1.369e-25	118.0	COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_8773120_1	261292.Nit79A3_0682	1.712e-147	475.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,371SP@32003|Nitrosomonadales	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
WLSH2_k127_8773120_0	795666.MW7_3261	4.435e-309	956.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,1JZU5@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WLSH2_k127_8773120_4	85643.Tmz1t_3854	7.591e-92	311.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2VMQB@28216|Betaproteobacteria,2KUKE@206389|Rhodocyclales	206389|Rhodocyclales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_8773120_5	522306.CAP2UW1_1986	6.238e-49	179.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,1KQWH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
WLSH2_k127_8773120_2	1163617.SCD_n01207	5.746e-136	459.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2VHW1@28216|Betaproteobacteria	28216|Betaproteobacteria	M	surface antigen	tama	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
WLSH2_k127_8773120_3	1158292.JPOE01000002_gene3180	2.592e-129	451.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2VJB8@28216|Betaproteobacteria,1KIV4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
WLSH2_k127_8781682_17	1288494.EBAPG3_3200	4.307e-15	77.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,371PI@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
WLSH2_k127_8781682_6	1236959.BAMT01000002_gene2249	4.391e-159	513.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,2KKDR@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
WLSH2_k127_8781682_2	1163617.SCD_n02559	2.548e-197	641.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
WLSH2_k127_8781682_9	265072.Mfla_2148	4.687e-137	443.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,2KM5S@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
WLSH2_k127_8781682_14	85643.Tmz1t_1452	2.208e-79	274.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,2KV5Z@206389|Rhodocyclales	206389|Rhodocyclales	JM	Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
WLSH2_k127_8781682_15	1158150.KB906241_gene516	4.164e-28	119.0	2CH9Q@1|root,344Q6@2|Bacteria,1P007@1224|Proteobacteria,1SS1R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_8781682_4	582744.Msip34_0582	9.215e-194	613.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,2KKCQ@206350|Nitrosomonadales	206350|Nitrosomonadales	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WLSH2_k127_8781682_11	1485544.JQKP01000020_gene53	2.43e-104	351.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,44V7V@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
WLSH2_k127_8781682_5	323848.Nmul_A0131	3.059e-176	560.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,371XV@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
WLSH2_k127_8781682_16	1163617.SCD_n00039	1.126e-24	109.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria	28216|Betaproteobacteria	KL	Belongs to the transcriptional regulatory Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
WLSH2_k127_8781682_0	1288494.EBAPG3_6260	1.864e-244	764.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,372QA@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WLSH2_k127_8781682_3	497321.C664_14409	3.113e-196	619.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,2KUEI@206389|Rhodocyclales	206389|Rhodocyclales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WLSH2_k127_8781682_7	1266925.JHVX01000008_gene267	2.387e-155	494.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,372SB@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
WLSH2_k127_8781682_1	580332.Slit_0282	1.61e-200	644.0	COG0515@1|root,COG3437@1|root,COG0515@2|Bacteria,COG3437@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WA3@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WLSH2_k127_8781682_10	580332.Slit_0281	1.653e-136	456.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VIMC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	dctB	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
WLSH2_k127_8781682_13	1392838.AWNM01000042_gene1575	3.042e-93	311.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,3T3A0@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WLSH2_k127_8781682_12	1392838.AWNM01000042_gene1576	3.951e-103	342.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,3T22A@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WLSH2_k127_8781682_8	1123401.JHYQ01000003_gene2053	1.609e-147	474.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,1RPTT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH2_k127_8860523_2	1123392.AQWL01000002_gene1858	4.057e-39	148.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,1KRZC@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Mur ligase family, catalytic domain	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH2_k127_8860523_0	1288494.EBAPG3_28220	5.647e-187	588.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,372PV@32003|Nitrosomonadales	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WLSH2_k127_8860523_1	1163617.SCD_n02487	3.744e-93	316.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH2_k127_891958_0	1163617.SCD_n01772	4.99e-227	709.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WLSH2_k127_891958_3	582744.Msip34_1461	7.612e-110	358.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,2KM99@206350|Nitrosomonadales	206350|Nitrosomonadales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WLSH2_k127_891958_1	1288494.EBAPG3_26760	7.711e-164	527.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,371ZV@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WLSH2_k127_891958_8	1035839.AFNK01000085_gene486	4.111e-06	50.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_891958_4	1485544.JQKP01000017_gene610	2.841e-104	348.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,44VE7@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WLSH2_k127_891958_2	1123367.C666_02565	2.675e-116	383.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,2KUHC@206389|Rhodocyclales	206389|Rhodocyclales	I	Squalene synthase HpnD	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WLSH2_k127_891958_5	1380394.JADL01000001_gene2346	3.729e-98	326.0	COG1028@1|root,COG1028@2|Bacteria,1QWBB@1224|Proteobacteria,2U2FD@28211|Alphaproteobacteria,2JVVT@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WLSH2_k127_891958_6	29581.BW37_01205	3.315e-48	176.0	COG2329@1|root,COG2329@2|Bacteria,1RGVV@1224|Proteobacteria,2VUVA@28216|Betaproteobacteria,474PZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WLSH2_k127_891958_7	580332.Slit_2852	8.748e-30	121.0	COG2149@1|root,COG2149@2|Bacteria,1N173@1224|Proteobacteria,2VWEE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
WLSH2_k127_9066054_11	395495.Lcho_3596	8.077e-47	173.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,1KITG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
WLSH2_k127_9066054_3	883126.HMPREF9710_03713	1.765e-132	432.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VI6W@28216|Betaproteobacteria,47253@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WLSH2_k127_9066054_7	1095769.CAHF01000006_gene1962	4.235e-114	373.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,472D5@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein, beta subunit	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WLSH2_k127_9066054_9	626418.bglu_1g13440	5.239e-73	256.0	COG0412@1|root,COG0412@2|Bacteria,1PKGT@1224|Proteobacteria,2VINS@28216|Betaproteobacteria,1K62P@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S15,Peptidase_S9
WLSH2_k127_9066054_0	1163617.SCD_n01785	5.371e-227	711.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
WLSH2_k127_9066054_4	1163617.SCD_n01786	2.621e-127	416.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WLSH2_k127_9066054_13	765910.MARPU_12270	3.09e-22	100.0	2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,1S92Y@1236|Gammaproteobacteria,1WYYH@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9066054_8	1123368.AUIS01000007_gene2759	9.228e-74	261.0	COG0518@1|root,COG0518@2|Bacteria,1MYXC@1224|Proteobacteria,1SJVW@1236|Gammaproteobacteria,2NCME@225057|Acidithiobacillales	225057|Acidithiobacillales	F	GMP synthase (glutamine-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9066054_6	159087.Daro_1985	1.919e-119	392.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria,2KU9Y@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WLSH2_k127_9066054_12	1255043.TVNIR_3413	9.232e-27	126.0	2FCC0@1|root,344FM@2|Bacteria,1NZRH@1224|Proteobacteria,1SRBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9066054_2	159087.Daro_1984	1.394e-179	572.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,2KU64@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH2_k127_9066054_10	1380394.JADL01000002_gene1437	1.379e-65	230.0	2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,2U9PI@28211|Alphaproteobacteria,2JT3N@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9066054_5	1123368.AUIS01000007_gene2763	3.104e-124	427.0	COG0667@1|root,COG0667@2|Bacteria,1RK6Z@1224|Proteobacteria,1SKN5@1236|Gammaproteobacteria,2NC9A@225057|Acidithiobacillales	225057|Acidithiobacillales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WLSH2_k127_9066054_1	1123368.AUIS01000007_gene2765	3.232e-217	695.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,1SMM0@1236|Gammaproteobacteria,2NBR8@225057|Acidithiobacillales	225057|Acidithiobacillales	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9079952_0	1000565.METUNv1_03400	2.238e-128	421.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,2KVG7@206389|Rhodocyclales	206389|Rhodocyclales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WLSH2_k127_9079952_1	1000565.METUNv1_03399	1.783e-100	331.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,2KVAA@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
WLSH2_k127_9079952_2	323848.Nmul_A2711	8.008e-99	329.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,372MM@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
WLSH2_k127_9079952_3	1163617.SCD_n00678	1.392e-37	146.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
WLSH2_k127_9105398_3	395494.Galf_1120	5.854e-22	95.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,44VQ0@713636|Nitrosomonadales	28216|Betaproteobacteria	DM	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
WLSH2_k127_9105398_0	1163617.SCD_n01285	3.967e-189	611.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM transglutaminase domain protein	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
WLSH2_k127_9105398_2	1163617.SCD_n01286	6.168e-90	307.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WLSH2_k127_9105398_1	580332.Slit_2221	1.727e-127	413.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities AAA_3	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH2_k127_9131400_2	580332.Slit_2743	9.76e-137	437.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,44UZX@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
WLSH2_k127_9131400_4	261292.Nit79A3_0176	9.414e-93	311.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,371V1@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A,Sugar-bind
WLSH2_k127_9131400_3	1485544.JQKP01000001_gene933	3.456e-93	311.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,44UZR@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WLSH2_k127_9131400_1	1266925.JHVX01000003_gene693	2.06e-184	589.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,371PP@32003|Nitrosomonadales	28216|Betaproteobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
WLSH2_k127_9131400_5	107635.AZUO01000001_gene1584	1.221e-48	183.0	COG0500@1|root,COG2226@2|Bacteria,1PVPS@1224|Proteobacteria,2TREE@28211|Alphaproteobacteria,370VV@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
WLSH2_k127_9131400_0	864051.BurJ1DRAFT_0984	3.082e-220	693.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,1KKFD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	polyphosphate kinase	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
WLSH2_k127_9131400_6	1163617.SCD_n02383	3.163e-46	172.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WLSH2_k127_9131400_7	1089551.KE386572_gene1794	7.252e-17	85.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2TQRV@28211|Alphaproteobacteria,4BQ58@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
WLSH2_k127_9151272_0	795666.MW7_3408	1.266e-215	674.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VK3Y@28216|Betaproteobacteria,1K3JP@119060|Burkholderiaceae	28216|Betaproteobacteria	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.4.1.24	ko:K16846	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	GD_AH_C
WLSH2_k127_9151272_4	204773.HEAR3336	7.617e-37	141.0	COG2721@1|root,COG2721@2|Bacteria,1MZBN@1224|Proteobacteria,2VU0R@28216|Betaproteobacteria	28216|Betaproteobacteria	G	SAF	-	-	4.4.1.24	ko:K16845	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	SAF
WLSH2_k127_9151272_2	713586.KB900536_gene717	1.47e-71	256.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,1RYZ9@1236|Gammaproteobacteria,1X0WT@135613|Chromatiales	135613|Chromatiales	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WLSH2_k127_9151272_3	1000565.METUNv1_02493	3.685e-55	196.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,2KWCD@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WLSH2_k127_9151272_1	279714.FuraDRAFT_1377	4.234e-105	347.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,2KPVV@206351|Neisseriales	206351|Neisseriales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WLSH2_k127_9151272_6	1163617.SCD_n02460	7.963e-18	83.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WLSH2_k127_9165017_1	1298867.AUES01000046_gene4088	1.054e-96	321.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,3JXHZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_9165017_4	1408164.MOLA814_00096	1.936e-46	174.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria,1KR30@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
WLSH2_k127_9165017_0	1123367.C666_09375	2.291e-107	354.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2VH81@28216|Betaproteobacteria,2KVGE@206389|Rhodocyclales	206389|Rhodocyclales	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WLSH2_k127_9165017_2	1163617.SCD_n00986	1.495e-73	258.0	2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,2VQ0G@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
WLSH2_k127_9165017_3	1123393.KB891316_gene1076	7.536e-55	194.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria,1KSTQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
WLSH2_k127_9221529_5	1157708.KB907458_gene1743	3.319e-93	316.0	COG3181@1|root,COG3181@2|Bacteria,1NR8P@1224|Proteobacteria,2W16Z@28216|Betaproteobacteria,4AGPI@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_9221529_0	1123487.KB892868_gene1204	7.418e-263	824.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KUY0@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yheS	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH2_k127_9221529_7	391615.ABSJ01000026_gene121	5.385e-73	257.0	2CIBN@1|root,2Z8JT@2|Bacteria,1R902@1224|Proteobacteria,1RXPM@1236|Gammaproteobacteria,1J8X1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9221529_4	338969.Rfer_3416	7.259e-96	319.0	COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2VQPA@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH2_k127_9221529_10	1238182.C882_4201	1.055e-23	105.0	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2UI14@28211|Alphaproteobacteria,2JUB3@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase subunit D	-	-	-	-	-	-	-	-	-	-	-	-	Fumarate_red_D
WLSH2_k127_9221529_9	1238182.C882_4200	8.646e-31	130.0	COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,2UFZX@28211|Alphaproteobacteria,2JUG8@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase subunit C	-	-	-	-	-	-	-	-	-	-	-	-	Fumarate_red_C
WLSH2_k127_9221529_3	1279038.KB907337_gene210	2.681e-102	338.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2U3AH@28211|Alphaproteobacteria,2JRIM@204441|Rhodospirillales	204441|Rhodospirillales	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_3,Fer4_8
WLSH2_k127_9221529_1	1238182.C882_4198	7.289e-256	801.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2U0QC@28211|Alphaproteobacteria,2JQ41@204441|Rhodospirillales	204441|Rhodospirillales	C	Fumarate reductase flavoprotein C-term	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
WLSH2_k127_9221529_8	742740.HMPREF9474_02621	9.122e-39	158.0	COG2084@1|root,COG2084@2|Bacteria,1V4MC@1239|Firmicutes,24KB8@186801|Clostridia	186801|Clostridia	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
WLSH2_k127_9221529_2	1288826.MSNKSG1_03265	1.057e-122	401.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,4652T@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG1230 Co Zn Cd efflux system component	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
WLSH2_k127_9221529_6	1123508.JH636447_gene7750	4.259e-76	264.0	COG0697@1|root,COG0697@2|Bacteria,2J42B@203682|Planctomycetes	203682|Planctomycetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH2_k127_9224632_3	93220.LV28_12595	6.194e-57	204.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1K3MD@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WLSH2_k127_9224632_1	292415.Tbd_1899	1.02e-125	409.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,1KRYU@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WLSH2_k127_9224632_2	323848.Nmul_A2749	1.083e-119	390.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,372BX@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	ABC transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WLSH2_k127_9224632_0	713586.KB900536_gene1410	5.436e-136	441.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,1SCEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Luciferase-like monooxygenase	luxA	-	1.14.14.3	ko:K00494	ko02020,ko02024,map02020,map02024	-	R10551	RC00080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
WLSH2_k127_9224632_4	396588.Tgr7_0733	1.507e-43	174.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WLSH2_k127_938039_7	1163617.SCD_n01927	1.289e-23	105.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WLSH2_k127_938039_5	1000565.METUNv1_00672	9.957e-33	130.0	COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,2VTZY@28216|Betaproteobacteria,2KX00@206389|Rhodocyclales	206389|Rhodocyclales	S	effector of murein hydrolase LrgA	-	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
WLSH2_k127_938039_0	159087.Daro_3106	9.414e-90	311.0	COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2VH4N@28216|Betaproteobacteria,2KVYR@206389|Rhodocyclales	206389|Rhodocyclales	M	of murein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LrgB
WLSH2_k127_938039_4	1163617.SCD_n02473	2.318e-50	197.0	COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
WLSH2_k127_938039_9	296591.Bpro_0926	3.546e-13	73.0	COG4876@1|root,COG4876@2|Bacteria,1NJCS@1224|Proteobacteria,2VYBB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_938039_6	1121918.ARWE01000001_gene103	8.392e-31	127.0	COG0517@1|root,COG0517@2|Bacteria,1QQRM@1224|Proteobacteria,42TVT@68525|delta/epsilon subdivisions,2WQBQ@28221|Deltaproteobacteria,43VA2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WLSH2_k127_938039_2	472759.Nhal_1647	1.859e-71	246.0	COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,1T3Z1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
WLSH2_k127_938039_3	1123392.AQWL01000003_gene118	1.205e-69	243.0	COG2823@1|root,COG2823@2|Bacteria,1RFX5@1224|Proteobacteria,2VRR5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	BON domain	osmY	-	-	-	-	-	-	-	-	-	-	-	BON
WLSH2_k127_938039_8	330214.NIDE3825	3.41e-17	93.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
WLSH2_k127_938039_1	1268622.AVS7_04525	3.372e-83	287.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_938039_10	583345.Mmol_0027	1.157e-10	63.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,2KNZ1@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
WLSH2_k127_9458393_0	713586.KB900536_gene2623	2.074e-229	720.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,1RMVE@1236|Gammaproteobacteria,1WWTX@135613|Chromatiales	135613|Chromatiales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
WLSH2_k127_9458393_10	1123501.KB902294_gene3522	1.176e-56	208.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_9458393_15	675635.Psed_0101	5.334e-12	73.0	COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4E0R9@85010|Pseudonocardiales	201174|Actinobacteria	S	protein involved in propionate catabolism	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
WLSH2_k127_9458393_2	1163617.SCD_n00536	3.088e-132	430.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria	28216|Betaproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
WLSH2_k127_9458393_7	1000565.METUNv1_02334	3.191e-60	215.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria,2KWQ6@206389|Rhodocyclales	206389|Rhodocyclales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	-	-	-	-	-	-	-	-	-	-	5-FTHF_cyc-lig
WLSH2_k127_9458393_11	1123261.AXDW01000014_gene3343	4.776e-54	199.0	COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,1S54H@1236|Gammaproteobacteria,1X61Q@135614|Xanthomonadales	135614|Xanthomonadales	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
WLSH2_k127_9458393_5	1123367.C666_05070	2.02e-109	367.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,2KUWU@206389|Rhodocyclales	206389|Rhodocyclales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
WLSH2_k127_9458393_3	1288494.EBAPG3_7390	8.579e-118	386.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,372NZ@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
WLSH2_k127_9458393_6	335283.Neut_2305	1.131e-61	222.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,372H5@32003|Nitrosomonadales	28216|Betaproteobacteria	GT	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
WLSH2_k127_9458393_14	1288494.EBAPG3_7400	4.64e-35	136.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,373ED@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Sigma 54 modulation protein	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
WLSH2_k127_9458393_1	1123393.KB891328_gene576	4.76e-177	567.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,1KRAY@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WLSH2_k127_9458393_4	1288494.EBAPG3_7420	2.964e-115	377.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,372DG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Branched-chain amino acid ATP-binding cassette transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
WLSH2_k127_9458393_9	1163617.SCD_n00559	5.335e-58	209.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
WLSH2_k127_9458393_13	1163617.SCD_n00560	2.538e-44	168.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
WLSH2_k127_9458393_12	1485544.JQKP01000001_gene1185	5.552e-46	172.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,44VQ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_3
WLSH2_k127_9458393_8	1218084.BBJK01000019_gene2018	1.064e-58	207.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,1K0GY@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
WLSH2_k127_9475188_9	1121920.AUAU01000023_gene2399	1.383e-49	177.0	COG0473@1|root,COG0473@2|Bacteria,3Y3YY@57723|Acidobacteria	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
WLSH2_k127_9475188_1	312153.Pnuc_0445	3.67e-225	708.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VH8Z@28216|Betaproteobacteria,1JZW1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WLSH2_k127_9475188_2	543913.D521_1839	2.086e-204	645.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,1KQ9H@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
WLSH2_k127_9475188_10	709797.CSIRO_0460	2.224e-49	182.0	COG4665@1|root,COG4665@2|Bacteria,1RHEX@1224|Proteobacteria,2UAEX@28211|Alphaproteobacteria,3K4HR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
WLSH2_k127_9475188_3	1458275.AZ34_00810	1.032e-200	633.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,4ABCI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
WLSH2_k127_9475188_8	742159.HMPREF0004_4664	1.463e-61	229.0	COG1513@1|root,COG1513@2|Bacteria,1R9X0@1224|Proteobacteria,2VQ5F@28216|Betaproteobacteria,3T7G3@506|Alcaligenaceae	28216|Betaproteobacteria	P	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide	cynS	-	4.2.1.104	ko:K01725	ko00910,map00910	-	R03546,R10079	RC00952	ko00000,ko00001,ko01000	-	-	-	Cyanate_lyase
WLSH2_k127_9475188_7	1205680.CAKO01000040_gene1016	4.465e-128	415.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TUIC@28211|Alphaproteobacteria,2JQGG@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K15578	ko00910,ko02010,map00910,map02010	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16.1	-	-	ABC_tran
WLSH2_k127_9475188_6	1205680.CAKO01000040_gene1015	3.077e-128	417.0	COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2TQT6@28211|Alphaproteobacteria,2JR63@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	ko:K02050,ko:K15577	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	BPD_transp_1
WLSH2_k127_9475188_0	1121033.AUCF01000002_gene584	3.314e-235	737.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2TS0X@28211|Alphaproteobacteria,2JRE4@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051,ko:K15576	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
WLSH2_k127_9475188_4	1163617.SCD_n00733	2.285e-174	559.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WLSH2_k127_9475188_5	1163617.SCD_n00732	1.796e-156	510.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria	28216|Betaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH2_k127_9490098_1	1163617.SCD_n01886	3.071e-87	292.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
WLSH2_k127_9490098_4	1123401.JHYQ01000047_gene162	2.852e-58	209.0	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,1S8DJ@1236|Gammaproteobacteria,463PP@72273|Thiotrichales	72273|Thiotrichales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
WLSH2_k127_9490098_0	765911.Thivi_4352	3.708e-119	394.0	COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,1RPGR@1236|Gammaproteobacteria,1WWYY@135613|Chromatiales	135613|Chromatiales	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
WLSH2_k127_9490098_5	207954.MED92_03258	1.292e-54	201.0	COG3821@1|root,COG3821@2|Bacteria,1RDXR@1224|Proteobacteria,1S43M@1236|Gammaproteobacteria,1XJVM@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF599
WLSH2_k127_9490098_2	375286.mma_1291	2.41e-79	277.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VJTU@28216|Betaproteobacteria,477DI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
WLSH2_k127_9490098_3	1463857.JOFZ01000001_gene5316	1.81e-68	246.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria	201174|Actinobacteria	E	ornithine cyclodeaminase	ocd	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
WLSH2_k127_9490098_6	748247.AZKH_4465	5.314e-21	100.0	COG3576@1|root,COG3576@2|Bacteria,1N8Z5@1224|Proteobacteria,2VVVW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9510738_0	1458275.AZ34_11045	1.028e-260	808.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAW5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
WLSH2_k127_9510738_4	543728.Vapar_4492	3.061e-52	191.0	2BKYI@1|root,32FF5@2|Bacteria,1MY1A@1224|Proteobacteria,2VRUQ@28216|Betaproteobacteria,4AERJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
WLSH2_k127_9510738_1	1458275.AZ34_11035	4.354e-160	512.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,4AC49@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_9510738_5	670307.HYPDE_24253	1.465e-27	117.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2UCYK@28211|Alphaproteobacteria,3N72F@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WLSH2_k127_9510738_3	909663.KI867150_gene271	1.777e-130	430.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,42MHN@68525|delta/epsilon subdivisions,2WJU0@28221|Deltaproteobacteria,2MQNQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
WLSH2_k127_9510738_2	983917.RGE_29000	5.56e-159	507.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2VKR6@28216|Betaproteobacteria,1KIXT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WLSH2_k127_9524347_0	1411123.JQNH01000001_gene2532	1.615e-105	347.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TSIV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	fructose-bisphosphate aldolase	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
WLSH2_k127_9524347_1	1380391.JIAS01000012_gene4477	1.013e-96	328.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,2JQ6A@204441|Rhodospirillales	204441|Rhodospirillales	S	cobalamin synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
WLSH2_k127_9524347_2	1120956.JHZK01000002_gene994	4.621e-32	128.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,1JP94@119043|Rhodobiaceae	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WLSH2_k127_9533732_3	580332.Slit_0460	1.429e-40	154.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,44VUQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
WLSH2_k127_9533732_1	1165096.ARWF01000001_gene999	3.308e-123	400.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,2KM7R@206350|Nitrosomonadales	206350|Nitrosomonadales	P	PFAM CBS domain	-	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
WLSH2_k127_9533732_0	323848.Nmul_A0552	8.561e-161	521.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,37222@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
WLSH2_k127_9533732_2	1437824.BN940_16516	1.282e-110	359.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,3T2BQ@506|Alcaligenaceae	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase, alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
WLSH2_k127_95684_1	62928.azo1661	1.33e-112	371.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,2KUDI@206389|Rhodocyclales	206389|Rhodocyclales	CM	Acyl-CoA synthetase (NDP forming)	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
WLSH2_k127_95684_2	292415.Tbd_2127	4.505e-20	91.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria,1KTG0@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH2_k127_95684_0	1163617.SCD_n00531	4.958e-141	451.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
WLSH2_k127_9587747_1	640081.Dsui_3084	9.916e-209	654.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,2KUCB@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
WLSH2_k127_9587747_4	395494.Galf_2330	5.817e-104	348.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,44V9I@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
WLSH2_k127_9587747_3	1163617.SCD_n00896	8.3e-143	469.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WLSH2_k127_9587747_8	323848.Nmul_A1884	2.314e-70	243.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,3731S@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
WLSH2_k127_9587747_6	1485544.JQKP01000001_gene883	1.131e-80	271.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,44VQD@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
WLSH2_k127_9587747_5	1163617.SCD_n00893	1.252e-81	278.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
WLSH2_k127_9587747_2	1123487.KB892834_gene2921	2.727e-182	578.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VI2K@28216|Betaproteobacteria,2KYAB@206389|Rhodocyclales	206389|Rhodocyclales	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
WLSH2_k127_9587747_7	395495.Lcho_0027	5.492e-71	249.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2VRAJ@28216|Betaproteobacteria,1KKQ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
WLSH2_k127_9587747_0	1288494.EBAPG3_25360	5.977e-251	781.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,3723J@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
WLSH2_k127_9587747_10	265072.Mfla_1693	1.468e-41	158.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,2KMQW@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
WLSH2_k127_9587747_11	1005048.CFU_1877	1.229e-26	117.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,4743J@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Sporulation related domain	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
WLSH2_k127_9587747_9	667632.KB890166_gene1440	1.448e-55	201.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,1K0DB@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH2_k127_9592432_3	1266925.JHVX01000009_gene81	3.596e-88	297.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,372KR@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the MtfA family	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
WLSH2_k127_9592432_4	1288494.EBAPG3_22330	2.188e-81	283.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,37224@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase,HTH_6,SIS
WLSH2_k127_9592432_5	76114.ebA2945	5.847e-75	256.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,2KW8P@206389|Rhodocyclales	206389|Rhodocyclales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WLSH2_k127_9592432_2	1000565.METUNv1_04051	2.691e-120	392.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,2KV23@206389|Rhodocyclales	206389|Rhodocyclales	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
WLSH2_k127_9592432_1	85643.Tmz1t_2450	5.125e-146	469.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
WLSH2_k127_9592432_7	85643.Tmz1t_3714	3.428e-39	153.0	COG0746@1|root,COG0746@2|Bacteria,1NBH1@1224|Proteobacteria,2WFP1@28216|Betaproteobacteria,2KXTC@206389|Rhodocyclales	206389|Rhodocyclales	H	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
WLSH2_k127_9592432_8	748247.AZKH_0071	8.267e-26	116.0	2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,2VWJH@28216|Betaproteobacteria,2KXB6@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3306
WLSH2_k127_9592432_0	204773.HEAR1409	3.697e-223	711.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,472MV@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
WLSH2_k127_9592432_6	1502852.FG94_01123	2.049e-39	154.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2VJ39@28216|Betaproteobacteria,474I7@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Nitrate reductase delta subunit	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
WLSH2_k127_9592432_9	365046.Rta_30520	0.0003638	46.0	2ENGM@1|root,33G44@2|Bacteria,1NIB7@1224|Proteobacteria,2VYFS@28216|Betaproteobacteria,4AG1A@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9595997_6	666681.M301_0397	7.169e-07	56.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,2VTZ2@28216|Betaproteobacteria,2KMT7@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM 17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
WLSH2_k127_9595997_0	757424.Hsero_3860	6.919e-215	680.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,473CU@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_9595997_5	640081.Dsui_0328	1.825e-15	77.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,2KV1E@206389|Rhodocyclales	206389|Rhodocyclales	O	COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH2_k127_9595997_1	477184.KYC_16547	5.379e-103	351.0	COG5002@1|root,COG5002@2|Bacteria,1QTSA@1224|Proteobacteria,2WGPM@28216|Betaproteobacteria,3T1RM@506|Alcaligenaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
WLSH2_k127_9595997_3	1163617.SCD_n02306	4.32e-85	287.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VQRM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH2_k127_9595997_2	323848.Nmul_A2296	4.844e-88	299.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,371XF@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Beta-lactamase enzyme family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
WLSH2_k127_9595997_4	1123368.AUIS01000007_gene2807	5.943e-81	280.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methyl-transferase	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
WLSH2_k127_9612682_7	1429916.X566_16350	3.697e-06	53.0	COG2159@1|root,COG2159@2|Bacteria,1Q4XY@1224|Proteobacteria,2U25S@28211|Alphaproteobacteria,3JUPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
WLSH2_k127_9612682_5	1266925.JHVX01000004_gene1166	4.555e-41	156.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,373ID@32003|Nitrosomonadales	28216|Betaproteobacteria	S	stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
WLSH2_k127_9612682_1	323848.Nmul_A1002	2.374e-108	352.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,372NI@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, N-terminal domain	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
WLSH2_k127_9612682_2	1123367.C666_01585	1.233e-100	333.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,2KUIS@206389|Rhodocyclales	206389|Rhodocyclales	P	Cytochrome C1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
WLSH2_k127_9612682_0	204773.HEAR3051	5.968e-210	661.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,4727H@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
WLSH2_k127_9612682_3	640081.Dsui_1812	9.198e-77	262.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,2KVZE@206389|Rhodocyclales	206389|Rhodocyclales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
WLSH2_k127_9612682_4	1366050.N234_20390	6.512e-73	257.0	COG3181@1|root,COG3181@2|Bacteria,1MVHU@1224|Proteobacteria,2VMFU@28216|Betaproteobacteria,1KCA9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_9612682_6	1449065.JMLL01000010_gene1531	1.512e-30	128.0	COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria,43KNU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	protein possibly involved in utilization of glycolate and propanediol	MA20_43165	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
WLSH2_k127_9622767_2	1123393.KB891316_gene2030	2.028e-56	197.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2WC4Z@28216|Betaproteobacteria,1KT6F@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrC like protein	-	-	-	-	-	-	-	-	-	-	-	-	DsrC
WLSH2_k127_9622767_0	1123393.KB891330_gene828	2.547e-190	595.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,1KRBV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WLSH2_k127_9622767_1	261292.Nit79A3_1727	1.633e-83	283.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,372TF@32003|Nitrosomonadales	28216|Betaproteobacteria	KT	PFAM Metal-dependent phosphohydrolase, HD	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,GAF_2,HD
WLSH2_k127_9705880_14	1117958.PE143B_0107215	5.473e-16	85.0	COG0725@1|root,COG0725@2|Bacteria,1PA2T@1224|Proteobacteria,1RQ5K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter substrate-binding protein	-	-	5.3.3.7	ko:K02020,ko:K22003	ko00660,ko02010,map00660,map02010	M00189	R02244	RC00668	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	SBP_bac_11
WLSH2_k127_9705880_8	1121106.JQKB01000005_gene2135	2.212e-45	175.0	COG0725@1|root,COG0725@2|Bacteria	2|Bacteria	P	tungstate binding	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
WLSH2_k127_9705880_5	1123060.JONP01000001_gene1673	2.048e-72	255.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JSUV@204441|Rhodospirillales	204441|Rhodospirillales	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_9705880_6	395494.Galf_2649	2.067e-62	220.0	COG3038@1|root,COG3038@2|Bacteria,1RBP8@1224|Proteobacteria,2VQWK@28216|Betaproteobacteria,44W0C@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prokaryotic cytochrome b561	yodB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
WLSH2_k127_9705880_0	204773.HEAR2554	4.526e-126	417.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2VNVS@28216|Betaproteobacteria,4759G@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WLSH2_k127_9705880_10	580332.Slit_2044	2.571e-24	108.0	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria,44WNR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9705880_3	365044.Pnap_1315	1.553e-102	346.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,4AAQW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
WLSH2_k127_9705880_9	1454004.AW11_00967	5.383e-36	141.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VTI1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	BON
WLSH2_k127_9705880_1	323848.Nmul_A2644	4.905e-117	388.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2VHC0@28216|Betaproteobacteria,373MJ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Pfam:UPF0118	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WLSH2_k127_9705880_11	1123393.KB891333_gene2539	9.49e-24	102.0	2C5IZ@1|root,33B4P@2|Bacteria,1NPIC@1224|Proteobacteria,2VVUV@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycine zipper 2TM domain	osmB	-	-	ko:K04062	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
WLSH2_k127_9705880_2	395495.Lcho_1854	6.2e-114	376.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2VIWG@28216|Betaproteobacteria,1KJRG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WLSH2_k127_9705880_4	1123393.KB891333_gene2538	8.668e-81	277.0	COG0664@1|root,COG0664@2|Bacteria,1RAF3@1224|Proteobacteria,2VQIC@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
WLSH2_k127_9705880_7	29581.BW37_05111	1.268e-46	176.0	COG3134@1|root,COG3134@2|Bacteria,1N0SK@1224|Proteobacteria,2WIIM@28216|Betaproteobacteria,474FG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
WLSH2_k127_9705880_13	1266925.JHVX01000001_gene2468	7.963e-18	83.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,2W8JG@28216|Betaproteobacteria,373T2@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH2_k127_9705880_15	640510.BC1001_0952	4.776e-14	72.0	2DR1A@1|root,339RT@2|Bacteria,1NGFB@1224|Proteobacteria,2VXU8@28216|Betaproteobacteria,1KB1T@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3096
WLSH2_k127_9705880_12	748247.AZKH_p0371	1.784e-22	102.0	2DRFV@1|root,33BJD@2|Bacteria,1NM2T@1224|Proteobacteria,2VXSE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
WLSH2_k127_9716945_6	228410.NE1963	5.295e-33	130.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2VQ2F@28216|Betaproteobacteria,372WR@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WLSH2_k127_9716945_0	323848.Nmul_A2069	9.662e-306	946.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,372RZ@32003|Nitrosomonadales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WLSH2_k127_9716945_5	1288494.EBAPG3_23290	9.026e-46	166.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,373DE@32003|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WLSH2_k127_9716945_7	1163617.SCD_n01036	1.092e-14	77.0	COG5416@1|root,COG5416@2|Bacteria	2|Bacteria	FG	Lipopolysaccharide assembly protein A domain	lapA	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
WLSH2_k127_9716945_1	640081.Dsui_1946	1.388e-162	524.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,2KU7Z@206389|Rhodocyclales	206389|Rhodocyclales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
WLSH2_k127_9716945_4	1163617.SCD_n01038	6.175e-87	293.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WLSH2_k127_9716945_2	1121035.AUCH01000001_gene2088	5.294e-122	402.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,2KV89@206389|Rhodocyclales	206389|Rhodocyclales	M	pfkB family carbohydrate kinase	-	-	2.7.1.167	ko:K21344	ko00540,map00540	M00064	R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WLSH2_k127_9716945_3	640081.Dsui_1953	7.718e-97	321.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,2KURF@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
WLSH2_k127_9974790_1	1357279.N018_25840	3.999e-135	441.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,1Z9FP@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WLSH2_k127_9974790_0	265072.Mfla_2758	6.422e-160	519.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,2KM2S@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WLSH2_k127_9988386_4	1121004.ATVC01000002_gene556	1.563e-115	380.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,2KPXI@206351|Neisseriales	206351|Neisseriales	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH2_k127_9988386_2	640081.Dsui_0630	7.765e-143	465.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,2KV07@206389|Rhodocyclales	206389|Rhodocyclales	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH2_k127_9988386_8	265072.Mfla_2196	3.777e-32	131.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KMZ0@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
WLSH2_k127_9988386_6	1163617.SCD_n00031	7.406e-40	155.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
WLSH2_k127_9988386_1	159087.Daro_2851	2.549e-238	741.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,2KUBN@206389|Rhodocyclales	206389|Rhodocyclales	E	O-acetylhomoserine	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
WLSH2_k127_9988386_5	472759.Nhal_3098	1.678e-102	347.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH2_k127_9988386_0	1415779.JOMH01000001_gene2583	6.155e-287	889.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1X4TP@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the IlvD Edd family	-	-	-	-	-	-	-	-	-	-	-	-	ILVD_EDD
WLSH2_k127_9988386_3	1163617.SCD_n00028	6.508e-120	398.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH2_k127_9988386_7	1122604.JONR01000003_gene1358	2.01e-36	151.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,1RQEK@1236|Gammaproteobacteria,1XCMR@135614|Xanthomonadales	135614|Xanthomonadales	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
WLSH2_k127_9988386_9	62928.azo0370	7.287e-29	118.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,2VQ6X@28216|Betaproteobacteria,2KW4E@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
WLSH2_k127_9989826_13	448385.sce1378	8.715e-18	92.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,433GE@68525|delta/epsilon subdivisions,2WYHA@28221|Deltaproteobacteria,2YVI4@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH2_k127_9989826_12	694429.Pyrfu_1622	6.594e-24	108.0	COG0066@1|root,arCOG02230@2157|Archaea,2XQNZ@28889|Crenarchaeota	28889|Crenarchaeota	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
WLSH2_k127_9989826_2	391616.OA238_c08020	2.122e-101	344.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TT8I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Aconitase family (aconitate hydratase)	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WLSH2_k127_9989826_3	391616.OA238_c08020	3.575e-94	340.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TT8I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Aconitase family (aconitate hydratase)	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WLSH2_k127_9989826_8	375286.mma_1291	1.675e-75	277.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VJTU@28216|Betaproteobacteria,477DI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
WLSH2_k127_9989826_1	243233.MCA0247	2.85e-150	484.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,1RNCD@1236|Gammaproteobacteria,1XG3K@135618|Methylococcales	135618|Methylococcales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WLSH2_k127_9989826_4	1123504.JQKD01000002_gene3790	1.127e-83	288.0	COG3181@1|root,COG3181@2|Bacteria,1MVW4@1224|Proteobacteria,2VPJZ@28216|Betaproteobacteria,4ABTW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_9989826_9	1100720.ALKN01000035_gene1005	1.301e-72	258.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4AB79@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_9989826_0	1205680.CAKO01000019_gene39	5.208e-202	643.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TT96@28211|Alphaproteobacteria,2JWK1@204441|Rhodospirillales	204441|Rhodospirillales	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WLSH2_k127_9989826_10	1123393.KB891327_gene311	2.757e-47	173.0	COG2259@1|root,COG2259@2|Bacteria,1MZC7@1224|Proteobacteria,2WANG@28216|Betaproteobacteria,1KT7P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
WLSH2_k127_9989826_11	1279017.AQYJ01000029_gene3723	3.557e-30	126.0	COG1917@1|root,COG1917@2|Bacteria,1R5IE@1224|Proteobacteria,1S3I4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH2_k127_9989826_7	568706.BN118_1402	2.067e-76	269.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,3T21B@506|Alcaligenaceae	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
WLSH2_k127_9989826_6	1394178.AWOO02000022_gene7157	4.94e-80	280.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria,4EHI5@85012|Streptosporangiales	201174|Actinobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
WLSH2_k127_9989826_5	388051.AUFE01000058_gene5878	1.356e-81	280.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2VSMI@28216|Betaproteobacteria,1KGM6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
## 1754 queries scanned
## Total time (seconds): 5.186830759048462
## Rate: 338.16 q/s