## Tue Dec 16 22:22:47 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WLSH3_bin.24.fa -m mmseqs --itype genome -o WLSH3_bin.24 --output_dir /data/result/bins/wyx/egg/WLSH3_bin.24 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WLSH3_k127_1002160_5	269799.Gmet_2043	4.051e-24	106.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42YJZ@68525|delta/epsilon subdivisions,2WWPU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KM	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B,TGFb_propeptide
WLSH3_k127_1002160_0	768670.Calni_0443	1.262e-96	327.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,2GENC@200930|Deferribacteres	200930|Deferribacteres	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
WLSH3_k127_1002160_2	552811.Dehly_1051	9.214e-54	198.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WLSH3_k127_1002160_1	1038859.AXAU01000027_gene2203	1.122e-57	210.0	COG0491@1|root,COG0491@2|Bacteria,1N6PM@1224|Proteobacteria,2TRZ4@28211|Alphaproteobacteria,3JSCF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH3_k127_1002160_6	1197906.CAJQ02000009_gene3536	2.708e-20	96.0	COG0664@1|root,COG0664@2|Bacteria,1RDJV@1224|Proteobacteria,2U73G@28211|Alphaproteobacteria,3JYP3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WLSH3_k127_1002160_3	1249975.JQLP01000005_gene2506	1.412e-47	195.0	COG1357@1|root,COG1361@1|root,COG1520@1|root,COG2304@1|root,COG2911@1|root,COG1357@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,4NMB8@976|Bacteroidetes,1IJKA@117743|Flavobacteriia	976|Bacteroidetes	M	Pfam C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,SdrD_B
WLSH3_k127_1002160_8	255470.cbdbA1717	8.339e-06	52.0	COG3266@1|root,COG3266@2|Bacteria,2G9UR@200795|Chloroflexi,34D8D@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
WLSH3_k127_1002160_4	314265.R2601_04438	7.455e-41	171.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
WLSH3_k127_1002160_7	1035191.HMPREF0185_00697	2.453e-15	82.0	COG0642@1|root,COG4252@1|root,COG2205@2|Bacteria,COG4252@2|Bacteria,1MUHS@1224|Proteobacteria,2U2TE@28211|Alphaproteobacteria,2KI3C@204458|Caulobacterales	204458|Caulobacterales	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,HATPase_c,PAS_4
WLSH3_k127_10095672_2	760568.Desku_1363	1.444e-23	101.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,261QG@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WLSH3_k127_10095672_0	243164.DET1372	9.807e-109	360.0	COG0167@1|root,COG0167@2|Bacteria,2G6RH@200795|Chloroflexi,34CMM@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WLSH3_k127_10095672_1	1449126.JQKL01000002_gene1538	9.625e-56	198.0	COG2122@1|root,COG2122@2|Bacteria,1TQ6A@1239|Firmicutes,249KT@186801|Clostridia	186801|Clostridia	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
WLSH3_k127_10130057_1	706587.Desti_2540	1.047e-34	136.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,2MREB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM thiamine pyrophosphate enzyme	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH3_k127_10130057_0	335543.Sfum_0115	1.375e-133	437.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MQT4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase alpha subunit	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH3_k127_10130057_2	96561.Dole_1393	8.331e-30	121.0	COG1144@1|root,COG1144@2|Bacteria,1N99V@1224|Proteobacteria,42V8C@68525|delta/epsilon subdivisions,2WRCP@28221|Deltaproteobacteria,2MMCF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
WLSH3_k127_10167466_1	768706.Desor_1207	4.231e-50	188.0	COG1788@1|root,COG2057@1|root,COG1788@2|Bacteria,COG2057@2|Bacteria,1UYH2@1239|Firmicutes	1239|Firmicutes	I	acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WLSH3_k127_10167466_0	1121422.AUMW01000010_gene1062	7.702e-60	212.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,261T9@186807|Peptococcaceae	186801|Clostridia	S	PFAM Appr-1-p processing	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
WLSH3_k127_10167466_2	1117314.PCIT_21980	1.616e-17	85.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,2Q5BA@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
WLSH3_k127_10181242_2	45157.CMQ082CT	1.911e-23	102.0	COG0141@1|root,KOG2697@2759|Eukaryota	2759|Eukaryota	E	histidinol dehydrogenase activity	HIS4	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009314,GO:0009411,GO:0009416,GO:0009507,GO:0009532,GO:0009536,GO:0009555,GO:0009570,GO:0009628,GO:0009987,GO:0016053,GO:0016462,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030145,GO:0032501,GO:0032502,GO:0034641,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0048229,GO:0048856,GO:0050896,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,3.5.4.19,3.6.1.31	ko:K00013,ko:K14152	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012,R04035,R04037	RC00002,RC00099,RC00242,RC00463,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh,PRA-CH,PRA-PH
WLSH3_k127_10181242_0	311424.DhcVS_747	1.984e-118	391.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi,34CIS@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_10181242_1	243164.DET0842	1.647e-39	151.0	COG0131@1|root,COG0131@2|Bacteria,2G6JA@200795|Chloroflexi,34D1H@301297|Dehalococcoidia	301297|Dehalococcoidia	E	imidazoleglycerol-phosphate dehydratase activity	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
WLSH3_k127_10207650_1	552811.Dehly_1421	2.263e-46	176.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi,34CWT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
WLSH3_k127_10207650_2	552811.Dehly_1420	1.031e-41	160.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi,34D1S@301297|Dehalococcoidia	301297|Dehalococcoidia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WLSH3_k127_10207650_3	552811.Dehly_1417	3.844e-08	55.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi,34D32@301297|Dehalococcoidia	301297|Dehalococcoidia	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
WLSH3_k127_10207650_0	243164.DET1425	1.381e-122	406.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi,34CK7@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WLSH3_k127_10335534_2	243164.DET0965	9.913e-30	122.0	COG0344@1|root,COG0344@2|Bacteria,2GARY@200795|Chloroflexi,34D74@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH3_k127_10335534_3	243164.DET1334	8.93e-22	97.0	COG0721@1|root,COG0721@2|Bacteria,2G763@200795|Chloroflexi,34DF5@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WLSH3_k127_10335534_0	1123511.KB905844_gene1179	7.803e-194	625.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,4H1Y3@909932|Negativicutes	909932|Negativicutes	J	elongation factor G	fusA_1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH3_k127_10335534_1	525904.Tter_1076	2.19e-91	305.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR1	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH3_k127_10335809_1	429009.Adeg_0469	7.728e-113	372.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,42EYC@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
WLSH3_k127_10335809_2	795359.TOPB45_0867	1.206e-37	149.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
WLSH3_k127_10335809_0	56780.SYN_00998	3.209e-117	389.0	COG1032@1|root,COG1032@2|Bacteria,1PTN9@1224|Proteobacteria,42MG9@68525|delta/epsilon subdivisions,2WJYU@28221|Deltaproteobacteria,2MR0G@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WLSH3_k127_103541_0	335543.Sfum_2687	8.323e-206	644.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,42MKE@68525|delta/epsilon subdivisions,2WJF1@28221|Deltaproteobacteria,2MR3P@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	PFAM Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WLSH3_k127_103541_3	1121430.JMLG01000013_gene1885	1.312e-83	283.0	COG3383@1|root,COG3383@2|Bacteria,1V1Y2@1239|Firmicutes,24FSX@186801|Clostridia,263ZV@186807|Peptococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	-	-	1.17.1.9,1.6.5.3	ko:K00123,ko:K00336	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_21,NADH-G_4Fe-4S_3
WLSH3_k127_103541_1	1121472.AQWN01000003_gene1546	2.703e-152	492.0	COG1960@1|root,COG1960@2|Bacteria,1TRR9@1239|Firmicutes,24AJB@186801|Clostridia,260H9@186807|Peptococcaceae	186801|Clostridia	I	PFAM Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_103541_2	933262.AXAM01000007_gene2026	1.176e-92	309.0	COG0778@1|root,COG0778@2|Bacteria,1MWMJ@1224|Proteobacteria,42R9J@68525|delta/epsilon subdivisions,2WN13@28221|Deltaproteobacteria,2MJNG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_10360205_4	439235.Dalk_2665	3.201e-47	175.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_10360205_0	439235.Dalk_2664	4.194e-146	477.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,42S7Z@68525|delta/epsilon subdivisions,2WNZM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2199	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_10360205_2	247633.GP2143_17291	3.264e-107	360.0	COG1960@1|root,COG1960@2|Bacteria,1R6EH@1224|Proteobacteria,1RMXW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_10360205_7	1101191.KI912577_gene3893	3.479e-14	76.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1MU4H@1224|Proteobacteria,2TRU5@28211|Alphaproteobacteria,1JU91@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EI	Allophanate hydrolase subunit 2	uca	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
WLSH3_k127_10360205_3	1313301.AUGC01000013_gene1249	7.743e-101	336.0	COG3246@1|root,COG3246@2|Bacteria,4NGNQ@976|Bacteroidetes	976|Bacteroidetes	S	3-keto-5-aminohexanoate cleavage protein	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
WLSH3_k127_10360205_5	378806.STAUR_3464	7.282e-32	128.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,42RTA@68525|delta/epsilon subdivisions,2WNCA@28221|Deltaproteobacteria,2YV29@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH3_k127_10360205_6	1415780.JPOG01000001_gene665	3.671e-26	113.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,1RP85@1236|Gammaproteobacteria,1X4RM@135614|Xanthomonadales	135614|Xanthomonadales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH3_k127_10360205_1	378806.STAUR_4741	7.491e-116	380.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2YWJZ@29|Myxococcales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
WLSH3_k127_10384160_5	352165.HMPREF7215_2230	1.419e-24	109.0	COG0222@1|root,COG0222@2|Bacteria,3TB80@508458|Synergistetes	508458|Synergistetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WLSH3_k127_10384160_4	697281.Mahau_2166	1.101e-26	116.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,42GM6@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WLSH3_k127_10384160_6	243164.DET0617	1.589e-21	97.0	2A4E8@1|root,30T02@2|Bacteria,2GAVS@200795|Chloroflexi,34DG0@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10384160_2	1121430.JMLG01000031_gene1636	7.429e-57	207.0	2BVIG@1|root,32QWN@2|Bacteria,1VS33@1239|Firmicutes,24YBP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10384160_0	1220534.B655_1468	4.701e-83	284.0	COG1355@1|root,arCOG01728@2157|Archaea,2XVYU@28890|Euryarchaeota,23P13@183925|Methanobacteria	183925|Methanobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
WLSH3_k127_10384160_3	309799.DICTH_1528	5.685e-40	154.0	COG0622@1|root,COG0622@2|Bacteria	2|Bacteria	S	retrograde transport, endosome to Golgi	ysnB	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
WLSH3_k127_10384160_7	243164.DET0363	8.051e-15	76.0	2A4G3@1|root,30T26@2|Bacteria,2GAY4@200795|Chloroflexi,34DJS@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10384160_9	1121405.dsmv_1970	1.277e-06	56.0	COG2329@1|root,COG2329@2|Bacteria,1NBCH@1224|Proteobacteria,42VX2@68525|delta/epsilon subdivisions,2WRPB@28221|Deltaproteobacteria,2MM0B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WLSH3_k127_10384160_10	196490.AUEZ01000055_gene235	0.0002916	46.0	2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,2U6KV@28211|Alphaproteobacteria,3JYM4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10384160_1	1232410.KI421413_gene633	1.674e-66	227.0	2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,42QWQ@68525|delta/epsilon subdivisions,2WMRI@28221|Deltaproteobacteria,43T93@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10405818_0	515635.Dtur_0078	2.76e-134	436.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
WLSH3_k127_10405818_1	1304875.JAFZ01000001_gene1215	2.573e-64	224.0	COG1941@1|root,COG1941@2|Bacteria,3TAAY@508458|Synergistetes	508458|Synergistetes	C	PFAM NADH ubiquinone oxidoreductase, 20	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
WLSH3_k127_10412969_0	243164.DET1208	2.135e-109	364.0	COG1208@1|root,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,34CN9@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WLSH3_k127_10412969_1	1343739.PAP_01435	8.039e-90	302.0	COG3769@1|root,arCOG04158@2157|Archaea,2XVSN@28890|Euryarchaeota,243EP@183968|Thermococci	183968|Thermococci	G	Transfers a mannosyl group from GDP-mannose to phosphoglycerate to form mannosyl-3-phosphoglycerate (MPG)	mngA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.4.1.217	ko:K05947	ko00051,map00051	-	R05768	RC00005,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Osmo_MPGsynth
WLSH3_k127_10486131_0	255470.cbdbA1601	1.476e-99	359.0	COG0784@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,34DMA@301297|Dehalococcoidia	301297|Dehalococcoidia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
WLSH3_k127_10486131_1	243164.DET0624	6.959e-95	322.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi,34CZJ@301297|Dehalococcoidia	301297|Dehalococcoidia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
WLSH3_k127_10486131_2	797299.HALLA_08105	6.98e-06	50.0	COG0529@1|root,arCOG01040@2157|Archaea,2XWW4@28890|Euryarchaeota,23V8B@183963|Halobacteria	183963|Halobacteria	P	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
WLSH3_k127_10545744_1	311424.DhcVS_6	2.572e-71	247.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi,34CWB@301297|Dehalococcoidia	301297|Dehalococcoidia	J	histidyl-tRNA aminoacylation	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WLSH3_k127_10545744_0	311424.DhcVS_4	1.082e-268	841.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi,34D61@301297|Dehalococcoidia	301297|Dehalococcoidia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WLSH3_k127_10545744_2	255470.cbdbA3	4.395e-38	148.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,34D3W@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH3_k127_10639539_9	552811.Dehly_0512	2.463e-08	58.0	2BQBB@1|root,32J6D@2|Bacteria,2GAWR@200795|Chloroflexi,34DHV@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10639539_0	255470.cbdbA726	6.896e-249	779.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi,34CIP@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
WLSH3_k127_10639539_5	552811.Dehly_0823	6.4e-47	175.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi,34DC4@301297|Dehalococcoidia	301297|Dehalococcoidia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WLSH3_k127_10639539_8	926569.ANT_00600	2.376e-11	66.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WLSH3_k127_10639539_6	243164.DET0750	1.499e-35	139.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi,34DDX@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WLSH3_k127_10639539_4	552811.Dehly_1236	5.16e-133	432.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi,34CPK@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WLSH3_k127_10639539_2	255470.cbdbA308	1.291e-230	739.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi,34CIT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WLSH3_k127_10639539_1	311424.DhcVS_312	3.474e-237	745.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi,34CJ8@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
WLSH3_k127_10639539_3	255470.cbdbA311	9.711e-144	464.0	COG0821@1|root,COG0821@2|Bacteria,2G5SC@200795|Chloroflexi,34CZY@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
WLSH3_k127_10639539_7	1476973.JMMB01000007_gene1272	1.636e-12	70.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,25R2P@186804|Peptostreptococcaceae	186801|Clostridia	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
WLSH3_k127_10733904_2	1499967.BAYZ01000016_gene6563	3.69e-14	72.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
WLSH3_k127_10733904_0	880072.Desac_2420	4.381e-286	917.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
WLSH3_k127_10733904_1	1144672.F966_02075	6.223e-40	161.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,3NM1J@468|Moraxellaceae	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	cupB5	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
WLSH3_k127_10785119_2	324602.Caur_1122	2.692e-48	173.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,376WB@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WLSH3_k127_10785119_1	1122217.KB899583_gene1248	1.629e-76	269.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4H26F@909932|Negativicutes	909932|Negativicutes	O	PDZ DHR GLGF domain protein	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin,Trypsin_2
WLSH3_k127_10785119_0	926569.ANT_22850	8.535e-187	600.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WLSH3_k127_10961686_3	485913.Krac_8193	1.055e-44	168.0	COG1957@1|root,COG1957@2|Bacteria,2G6R6@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
WLSH3_k127_10961686_4	635013.TherJR_0365	1.733e-34	138.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,261K3@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
WLSH3_k127_10961686_0	264732.Moth_2254	4.409e-123	407.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,42F1K@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
WLSH3_k127_10961686_2	1303518.CCALI_01951	1.898e-58	210.0	COG0177@1|root,COG0177@2|Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WLSH3_k127_10961686_1	1094980.Mpsy_1197	8.478e-71	248.0	COG1497@1|root,arCOG04399@2157|Archaea,2XU16@28890|Euryarchaeota,2N9I6@224756|Methanomicrobia	224756|Methanomicrobia	K	SMART regulatory protein, Crp	-	-	-	ko:K07730	-	-	-	-	ko00000,ko03000	-	-	-	HTH_24,MarR_2
WLSH3_k127_11026647_2	697281.Mahau_1423	2.181e-88	299.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,42F1H@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WLSH3_k127_11026647_3	1507.HMPREF0262_02120	3.388e-82	290.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,36DT0@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
WLSH3_k127_11026647_4	255470.cbdbA1112	3.552e-64	226.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,34D9M@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
WLSH3_k127_11026647_1	243164.DET0343	6.111e-145	468.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi,34D9X@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WLSH3_k127_11026647_0	255470.cbdbA283	3.122e-152	491.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi,34CNF@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	-	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WLSH3_k127_11116077_5	1121342.AUCO01000029_gene2543	0.0001063	47.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,36EQY@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
WLSH3_k127_11116077_2	1123226.KB899286_gene3420	2.018e-70	244.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli,26S1K@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WLSH3_k127_11116077_1	311424.DhcVS_510	9.762e-94	322.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
WLSH3_k127_11116077_0	255470.cbdbA543	1.689e-137	446.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,34CN2@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH3_k127_11116077_3	472759.Nhal_3538	1.909e-68	240.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,1RRYH@1236|Gammaproteobacteria,1X059@135613|Chromatiales	135613|Chromatiales	L	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
WLSH3_k127_11116077_4	633148.Tagg_0084	7.823e-53	205.0	COG1269@1|root,arCOG04138@2157|Archaea,2XQ7V@28889|Crenarchaeota	28889|Crenarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019899,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0045851,GO:0046034,GO:0046390,GO:0046483,GO:0046961,GO:0048878,GO:0050801,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
WLSH3_k127_11126417_2	330214.NIDE3111	6.139e-39	151.0	COG0179@1|root,COG0179@2|Bacteria,3J1AP@40117|Nitrospirae	40117|Nitrospirae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
WLSH3_k127_11126417_1	1449126.JQKL01000058_gene2235	2.86e-162	532.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,2682T@186813|unclassified Clostridiales	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
WLSH3_k127_11126417_0	243164.DET1464	0.0	1341.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi,34CSK@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA-directed DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH3_k127_11126417_3	1449126.JQKL01000030_gene2486	2.416e-17	85.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,267WZ@186813|unclassified Clostridiales	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
WLSH3_k127_11145884_0	96561.Dole_2365	1.096e-79	274.0	COG1024@1|root,COG1024@2|Bacteria,1R56Y@1224|Proteobacteria,42MRW@68525|delta/epsilon subdivisions,2WKNI@28221|Deltaproteobacteria,2MJAI@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH3_k127_11145884_1	552811.Dehly_1409	5.046e-67	235.0	COG0378@1|root,COG0378@2|Bacteria,2G6EP@200795|Chloroflexi,34CKU@301297|Dehalococcoidia	301297|Dehalococcoidia	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
WLSH3_k127_11145884_2	552811.Dehly_1408	2.842e-27	113.0	COG0375@1|root,COG0375@2|Bacteria,2G77T@200795|Chloroflexi,34DD7@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
WLSH3_k127_11204510_9	243164.DET0835	1.053e-41	158.0	COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi,34CQJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
WLSH3_k127_11204510_0	311424.DhcVS_740	3.892e-260	811.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G5WB@200795|Chloroflexi,34CZX@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
WLSH3_k127_11204510_11	1122947.FR7_1654	1.875e-10	64.0	COG3461@1|root,COG3461@2|Bacteria,1UKQB@1239|Firmicutes,4H67E@909932|Negativicutes	909932|Negativicutes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_11204510_4	1268072.PSAB_03110	1.341e-134	440.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,26SBN@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
WLSH3_k127_11204510_8	255470.cbdbA820	3.603e-46	170.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi,34CSG@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WLSH3_k127_11204510_2	255470.cbdbA821	3.769e-195	617.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,34CSN@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WLSH3_k127_11204510_1	439235.Dalk_1215	2.968e-213	671.0	COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,42NUH@68525|delta/epsilon subdivisions,2WISE@28221|Deltaproteobacteria,2MI4T@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal	-	-	4.2.1.120,5.3.3.3	ko:K14534	ko00650,ko00720,ko01100,ko01120,ko01200,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R03031,R10782	RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
WLSH3_k127_11204510_6	243164.DET0841	2.467e-101	339.0	COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,34CSI@301297|Dehalococcoidia	301297|Dehalococcoidia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WLSH3_k127_11204510_5	526227.Mesil_3101	7.026e-117	384.0	COG0205@1|root,COG0205@2|Bacteria,1WINW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WLSH3_k127_11204510_13	1123075.AUDP01000011_gene1910	9.006e-06	55.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,3WPXI@541000|Ruminococcaceae	186801|Clostridia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
WLSH3_k127_11204510_7	439481.Aboo_0039	2.021e-95	323.0	COG0549@1|root,arCOG00863@2157|Archaea,2XTCB@28890|Euryarchaeota,3F2X1@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	Amino acid kinase family	cpkA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH3_k127_11204510_3	927658.AJUM01000037_gene2274	4.606e-190	603.0	COG2403@1|root,COG2403@2|Bacteria,4NHIW@976|Bacteroidetes,2FNNX@200643|Bacteroidia	976|Bacteroidetes	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_11204510_12	592015.HMPREF1705_00135	9.992e-08	56.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	asnB	-	6.3.3.6,6.3.5.4	ko:K01953,ko:K18316	ko00250,ko00332,ko01100,ko01110,ko01130,ko02024,map00250,map00332,map01100,map01110,map01130,map02024	M00675	R00578,R10556	RC00010,RC03195	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
WLSH3_k127_11204510_10	1391647.AVSV01000003_gene1672	9.402e-31	126.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,36I5H@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH3_k127_11283844_2	479433.Caci_2139	6.091e-65	232.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
WLSH3_k127_11283844_3	643562.Daes_0095	2.033e-09	66.0	COG4122@1|root,COG4122@2|Bacteria,1N2AR@1224|Proteobacteria,439ZI@68525|delta/epsilon subdivisions,2X2GU@28221|Deltaproteobacteria,2MDMY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
WLSH3_k127_11283844_1	243164.DET0380	5.475e-147	469.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi,34D6P@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
WLSH3_k127_11283844_0	525904.Tter_0684	6.406e-149	476.0	COG3854@1|root,COG3854@2|Bacteria,2NQEN@2323|unclassified Bacteria	2|Bacteria	S	R3H domain	ycf45	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
WLSH3_k127_11322886_3	909663.KI867150_gene2405	2.467e-23	103.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2MREJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH3_k127_11322886_0	1047013.AQSP01000126_gene2726	4.752e-218	688.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
WLSH3_k127_11322886_1	56780.SYN_00469	6.929e-74	251.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria,2MQDS@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH3_k127_11322886_2	706587.Desti_1467	9.418e-36	140.0	COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,430JJ@68525|delta/epsilon subdivisions,2WVQQ@28221|Deltaproteobacteria,2MRZH@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
WLSH3_k127_1132345_1	909663.KI867150_gene1507	1.353e-81	277.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,2MRP7@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WLSH3_k127_1132345_2	909663.KI867150_gene2949	1.392e-78	276.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
WLSH3_k127_1132345_3	909663.KI867150_gene1506	7.128e-51	198.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,42NFZ@68525|delta/epsilon subdivisions,2WMBX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
WLSH3_k127_1132345_0	1128421.JAGA01000003_gene3395	9.94e-103	344.0	COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH3_k127_11339462_3	243164.DET1448	4.887e-17	81.0	29WVC@1|root,30IH0@2|Bacteria,2G9KW@200795|Chloroflexi,34DPM@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_11339462_1	511051.CSE_01440	1.596e-29	123.0	COG2426@1|root,COG2426@2|Bacteria	2|Bacteria	S	small multidrug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
WLSH3_k127_11339462_0	272844.PAB1666	4.22e-83	293.0	COG1109@1|root,arCOG00767@2157|Archaea,2XT1X@28890|Euryarchaeota,242T7@183968|Thermococci	183968|Thermococci	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH3_k127_11339462_2	868131.MSWAN_0358	2.171e-20	101.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,23NRH@183925|Methanobacteria	183925|Methanobacteria	M	Bacterial transferase hexapeptide repeat	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WLSH3_k127_11447440_0	311424.DhcVS_999	9.959e-131	431.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi,34CKY@301297|Dehalococcoidia	301297|Dehalococcoidia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
WLSH3_k127_11447440_1	255470.cbdbA1133	5.579e-66	235.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi,34D04@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WLSH3_k127_11447440_2	335543.Sfum_2480	2.194e-60	214.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2MQC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WLSH3_k127_11489944_5	1349785.BAUG01000036_gene1990	0.0005712	47.0	COG4870@1|root,COG4886@1|root,COG4870@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia	976|Bacteroidetes	P	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF285,LRR_4,TSP_3
WLSH3_k127_11489944_1	373903.Hore_08960	2.87e-43	164.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3WARF@53433|Halanaerobiales	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WLSH3_k127_11489944_3	484019.THA_1384	1.204e-16	82.0	COG0695@1|root,COG0695@2|Bacteria,2GD7W@200918|Thermotogae	200918|Thermotogae	O	glutaredoxin-like protein, YruB-family	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
WLSH3_k127_11489944_0	760568.Desku_2692	3.824e-101	338.0	COG3634@1|root,COG3634@2|Bacteria,1UIUB@1239|Firmicutes,25ES4@186801|Clostridia,267GT@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2,Thioredoxin_3
WLSH3_k127_11489944_2	552811.Dehly_0955	3.308e-38	149.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH3_k127_11553697_4	593750.Metfor_2724	5.162e-45	168.0	COG0701@1|root,arCOG02712@2157|Archaea,2XT2F@28890|Euryarchaeota,2NAE3@224756|Methanomicrobia	224756|Methanomicrobia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WLSH3_k127_11553697_6	255470.cbdbA966	2.441e-22	101.0	COG0640@1|root,COG0640@2|Bacteria,2GAVR@200795|Chloroflexi,34DFX@301297|Dehalococcoidia	301297|Dehalococcoidia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
WLSH3_k127_11553697_8	304371.MCP_0686	1.844e-18	89.0	COG1917@1|root,arCOG03002@2157|Archaea	2157|Archaea	S	Cupin 2 conserved barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,DUF2249
WLSH3_k127_11553697_1	1220534.B655_2206	2.547e-85	290.0	COG0842@1|root,arCOG01463@2157|Archaea,2XX4N@28890|Euryarchaeota	28890|Euryarchaeota	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WLSH3_k127_11553697_0	1220534.B655_2207	5.996e-107	355.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT0T@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system ATPase component	nosF1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH3_k127_11553697_2	386456.JQKN01000010_gene670	3.973e-83	283.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XSXC@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
WLSH3_k127_11553697_9	1343739.PAP_03045	3.539e-12	71.0	COG0640@1|root,arCOG01680@2157|Archaea,2XZK6@28890|Euryarchaeota,244AD@183968|Thermococci	183968|Thermococci	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
WLSH3_k127_11553697_5	224325.AF_0187	8.403e-40	151.0	COG2044@1|root,arCOG02066@2157|Archaea,2XWA5@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM DsrE family protein	-	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,TusA
WLSH3_k127_11553697_7	1047013.AQSP01000144_gene918	7.278e-21	96.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.14,2.8.1.7	ko:K00549,ko:K04085,ko:K04487,ko:K08363	ko00270,ko00450,ko00730,ko01100,ko01110,ko01230,ko04122,map00270,map00450,map00730,map01100,map01110,map01230,map04122	M00017	R04405,R07460,R09365,R11528,R11529	RC00035,RC00113,RC01241,RC01789,RC02313	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048,ko03016,ko03029	1.A.72.1	-	-	DUF2249,Rhodanese,TusA
WLSH3_k127_11553697_10	255470.cbdbA905	5.593e-07	55.0	2A4FW@1|root,30T1V@2|Bacteria,2GAXQ@200795|Chloroflexi,34DJ6@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_11553697_3	909663.KI867150_gene222	9.928e-58	203.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,42MT6@68525|delta/epsilon subdivisions,2WJBU@28221|Deltaproteobacteria,2MRQU@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NifU-like N terminal domain	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WLSH3_k127_1189487_3	383372.Rcas_4310	1.108e-57	205.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,374TE@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH3_k127_1189487_4	1170562.Cal6303_2768	4.866e-44	162.0	COG0399@1|root,COG0399@2|Bacteria,1GDTU@1117|Cyanobacteria,1HSKF@1161|Nostocales	1117|Cyanobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WLSH3_k127_1189487_1	311424.DhcVS_649	1.084e-82	283.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi,34CU5@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WLSH3_k127_1189487_0	243164.DET0744	7.832e-154	495.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi,34D75@301297|Dehalococcoidia	301297|Dehalococcoidia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WLSH3_k127_1189487_2	351160.RCIX1254	3.713e-63	225.0	COG0142@1|root,arCOG01726@2157|Archaea,2XTAC@28890|Euryarchaeota,2N97R@224756|Methanomicrobia	224756|Methanomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WLSH3_k127_1207903_5	572547.Amico_1562	0.0006968	44.0	COG0534@1|root,COG0534@2|Bacteria,3T9QI@508458|Synergistetes	508458|Synergistetes	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WLSH3_k127_1207903_1	880072.Desac_2119	4.575e-110	362.0	COG1148@1|root,COG1148@2|Bacteria,1RB0H@1224|Proteobacteria,42QQV@68525|delta/epsilon subdivisions,2WN7E@28221|Deltaproteobacteria,2MRI3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH3_k127_1207903_0	555088.DealDRAFT_0127	6.204e-226	719.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
WLSH3_k127_1207903_3	1094980.Mpsy_1071	3.406e-25	115.0	arCOG07660@1|root,arCOG07660@2157|Archaea,2Y0ZQ@28890|Euryarchaeota,2NB4M@224756|Methanomicrobia	224756|Methanomicrobia	S	zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1207903_2	439292.Bsel_0300	6.799e-42	166.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4
WLSH3_k127_1207903_4	1121930.AQXG01000001_gene967	4.342e-05	47.0	COG2801@1|root,COG2801@2|Bacteria,4NVJX@976|Bacteroidetes	976|Bacteroidetes	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve,rve_3
WLSH3_k127_1228346_6	177437.HRM2_48400	1.419e-18	88.0	COG3387@1|root,COG3387@2|Bacteria,1NB01@1224|Proteobacteria,42N48@68525|delta/epsilon subdivisions,2WJRY@28221|Deltaproteobacteria,2MHXM@213118|Desulfobacterales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1228346_3	243164.DET0776	1.667e-72	251.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi,34CP5@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WLSH3_k127_1228346_7	661478.OP10G_3184	6.635e-09	61.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
WLSH3_k127_1228346_5	794903.OPIT5_05705	3.252e-30	133.0	COG0845@1|root,COG0845@2|Bacteria,46TJP@74201|Verrucomicrobia,3K7D1@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
WLSH3_k127_1228346_0	1128421.JAGA01000002_gene895	2.3e-91	304.0	COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
WLSH3_k127_1228346_1	401526.TcarDRAFT_0461	7.407e-86	299.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WLSH3_k127_1228346_2	243164.DET1204	1.066e-76	260.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,34D51@301297|Dehalococcoidia	301297|Dehalococcoidia	F	GTP cyclohydrolase I activity	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WLSH3_k127_1228346_4	552811.Dehly_0963	1.071e-47	175.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WLSH3_k127_1240442_0	1121447.JONL01000007_gene1153	3.913e-119	398.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42QF7@68525|delta/epsilon subdivisions,2WJAU@28221|Deltaproteobacteria,2MG0X@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART ATP-binding region ATPase domain protein, histidine kinase A domain protein, histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	2CSK_N,HAMP,HATPase_c,HisKA,PAS_9,Response_reg
WLSH3_k127_1240442_1	1121447.JONL01000007_gene1152	3.282e-97	322.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,2M9HT@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_1240442_2	316274.Haur_2171	1.326e-19	89.0	COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi,376D3@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH3_k127_1303876_0	1121472.AQWN01000006_gene1831	5.153e-126	417.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
WLSH3_k127_1303876_1	1304874.JAFY01000005_gene1372	3.133e-123	418.0	COG3383@1|root,COG3383@2|Bacteria,3TAAU@508458|Synergistetes	508458|Synergistetes	C	-binding domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
WLSH3_k127_1303876_2	1304875.JAFZ01000001_gene1215	4.777e-11	63.0	COG1941@1|root,COG1941@2|Bacteria,3TAAY@508458|Synergistetes	508458|Synergistetes	C	PFAM NADH ubiquinone oxidoreductase, 20	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
WLSH3_k127_1401566_2	429009.Adeg_0470	1.039e-86	293.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,42ET8@68295|Thermoanaerobacterales	186801|Clostridia	G	Transketolase, central region	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WLSH3_k127_1401566_8	515635.Dtur_1709	1.66e-51	187.0	COG3359@1|root,COG3359@2|Bacteria	2|Bacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
WLSH3_k127_1401566_11	880072.Desac_1106	3.91e-12	67.0	2E32K@1|root,32Y2U@2|Bacteria,1NJTE@1224|Proteobacteria,42WY3@68525|delta/epsilon subdivisions,2WSR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1401566_3	1449126.JQKL01000034_gene1268	1.84e-83	283.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,267NV@186813|unclassified Clostridiales	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
WLSH3_k127_1401566_0	1121468.AUBR01000046_gene1901	3.011e-189	599.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,42FMG@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
WLSH3_k127_1401566_1	1382306.JNIM01000001_gene2563	8.606e-92	316.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
WLSH3_k127_1401566_10	667014.Thein_1874	4.583e-38	148.0	COG1586@1|root,COG1586@2|Bacteria,2GGST@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
WLSH3_k127_1401566_5	1379698.RBG1_1C00001G0708	3.745e-80	278.0	COG0010@1|root,COG0010@2|Bacteria,2NPGU@2323|unclassified Bacteria	2|Bacteria	E	Arginase family	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WLSH3_k127_1401566_4	255470.cbdbA741	6.667e-81	283.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,34D00@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
WLSH3_k127_1401566_9	867903.ThesuDRAFT_00292	1.284e-39	154.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3WDTC@538999|Clostridiales incertae sedis	186801|Clostridia	U	TIGRFAM signal peptidase I, bacterial type	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WLSH3_k127_1401566_7	243164.DET1193	3.887e-60	213.0	COG0461@1|root,COG0461@2|Bacteria,2G6RG@200795|Chloroflexi,34CZB@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
WLSH3_k127_1401566_12	509191.AEDB02000003_gene1019	9.178e-06	50.0	2DPV4@1|root,333HA@2|Bacteria,1VH7Z@1239|Firmicutes,24SC2@186801|Clostridia,3WQ8C@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1401566_6	1121428.DESHY_60294___1	3.465e-69	238.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,26219@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
WLSH3_k127_1401566_13	1173024.KI912149_gene6401	5.159e-05	46.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria,1JMBS@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Acyl-carrier	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH3_k127_1470590_4	289377.HL41_05365	1.7e-15	76.0	COG0256@1|root,COG0256@2|Bacteria,2GHU6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
WLSH3_k127_1470590_1	1274524.BSONL12_22074	6.336e-46	171.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli,1ZBWE@1386|Bacillus	91061|Bacilli	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
WLSH3_k127_1470590_2	243164.DET0493	4.093e-43	161.0	COG0200@1|root,COG0200@2|Bacteria,2G6T9@200795|Chloroflexi,34CY2@301297|Dehalococcoidia	301297|Dehalococcoidia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
WLSH3_k127_1470590_0	243164.DET0494	4.171e-160	515.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi,34CNS@301297|Dehalococcoidia	301297|Dehalococcoidia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WLSH3_k127_1470590_3	373903.Hore_01370	3.304e-20	91.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WAJC@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
WLSH3_k127_1471776_0	243164.DET1481	2.378e-191	608.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,34CJD@301297|Dehalococcoidia	301297|Dehalococcoidia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
WLSH3_k127_1471776_2	311424.DhcVS_1253	3.427e-119	392.0	COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi,34CJV@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	-	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
WLSH3_k127_1471776_3	311424.DhcVS_1254	2.25e-77	267.0	COG0134@1|root,COG0134@2|Bacteria,2G6GG@200795|Chloroflexi,34D20@301297|Dehalococcoidia	301297|Dehalococcoidia	E	indole-3-glycerol-phosphate synthase activity	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
WLSH3_k127_1471776_4	311424.DhcVS_1255	4.505e-59	211.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi,34CSX@301297|Dehalococcoidia	301297|Dehalococcoidia	E	phosphoribosylanthranilate isomerase activity	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
WLSH3_k127_1471776_1	525904.Tter_1249	3.128e-160	510.0	COG0133@1|root,COG0133@2|Bacteria,2NNWF@2323|unclassified Bacteria	2|Bacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH3_k127_1492965_0	552811.Dehly_0475	4.763e-99	328.0	COG1149@1|root,COG1149@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,Fer4
WLSH3_k127_1492965_4	1265505.ATUG01000001_gene3955	3.1e-08	57.0	2DPG1@1|root,331X6@2|Bacteria,1NCJ5@1224|Proteobacteria,42W03@68525|delta/epsilon subdivisions,2WS3G@28221|Deltaproteobacteria,2MKUZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH3_k127_1492965_2	744872.Spica_2810	3.25e-40	153.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WLSH3_k127_1492965_1	459495.SPLC1_S531610	7.718e-43	164.0	COG0500@1|root,COG2226@2|Bacteria,1G6FT@1117|Cyanobacteria,1HAYS@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH3_k127_1492965_3	192952.MM_1231	6.119e-24	104.0	arCOG02703@1|root,arCOG02703@2157|Archaea	2157|Archaea	S	Methyltransferase type 11	aknG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
WLSH3_k127_1639934_3	445972.ANACOL_01359	0.0005231	44.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3WHA4@541000|Ruminococcaceae	186801|Clostridia	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
WLSH3_k127_1639934_2	255470.cbdbA509	2.129e-82	285.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi,34CM2@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WLSH3_k127_1639934_0	580331.Thit_1782	8.599e-138	451.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,42EZT@68295|Thermoanaerobacterales	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18870	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WLSH3_k127_1639934_1	1382306.JNIM01000001_gene1290	1.187e-94	313.0	COG0473@1|root,COG0473@2|Bacteria,2G68P@200795|Chloroflexi	200795|Chloroflexi	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WLSH3_k127_1714120_6	370438.PTH_0468	0.0001919	44.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,2617J@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WLSH3_k127_1714120_4	1209989.TepiRe1_2839	6.447e-24	105.0	COG1943@1|root,COG1943@2|Bacteria,1VCIB@1239|Firmicutes,24MZS@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WLSH3_k127_1714120_2	289376.THEYE_A1293	6.466e-58	208.0	COG2078@1|root,COG2078@2|Bacteria	2|Bacteria	S	ferrous iron binding	amrA	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
WLSH3_k127_1714120_0	552811.Dehly_0351	1.687e-183	583.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi,34CVS@301297|Dehalococcoidia	301297|Dehalococcoidia	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
WLSH3_k127_1714120_3	479434.Sthe_3131	2.112e-40	157.0	COG1392@1|root,COG1392@2|Bacteria,2G8VT@200795|Chloroflexi	200795|Chloroflexi	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
WLSH3_k127_1714120_1	311424.DhcVS_32	1.969e-117	386.0	COG0306@1|root,COG0306@2|Bacteria,2G7NA@200795|Chloroflexi,34D49@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
WLSH3_k127_1714120_5	311424.DhcVS_529	1.096e-11	68.0	COG0206@1|root,COG0206@2|Bacteria,2GAMG@200795|Chloroflexi,34CRX@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Involved in cell shape control	-	-	-	ko:K22222	-	-	-	-	ko00000,ko04812	-	-	-	Tubulin
WLSH3_k127_1750376_0	311424.DhcVS_910	4.744e-73	254.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi,34D1I@301297|Dehalococcoidia	301297|Dehalococcoidia	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
WLSH3_k127_1750376_1	243164.DET1041	3.917e-54	205.0	COG1520@1|root,COG1520@2|Bacteria,2GBGD@200795|Chloroflexi,34D1R@301297|Dehalococcoidia	301297|Dehalococcoidia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
WLSH3_k127_1750376_4	552811.Dehly_0750	8.432e-23	100.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi,34DPX@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WLSH3_k127_1750376_3	926550.CLDAP_04250	3.736e-23	102.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi	200795|Chloroflexi	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WLSH3_k127_1750376_6	1382356.JQMP01000003_gene1810	7.607e-13	68.0	COG0230@1|root,COG0230@2|Bacteria,2G7BX@200795|Chloroflexi,27YQV@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
WLSH3_k127_1750376_5	552811.Dehly_0753	2.387e-19	92.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi,34DBB@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WLSH3_k127_1750376_2	552811.Dehly_0754	6.687e-38	145.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi,34DBK@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Single-strand binding protein family	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH3_k127_1846_2	903818.KI912269_gene285	6.659e-125	409.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	BBE,FAD_binding_4
WLSH3_k127_1846_1	903818.KI912269_gene284	3.657e-158	509.0	COG0247@1|root,COG0247@2|Bacteria,3Y3RK@57723|Acidobacteria	57723|Acidobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
WLSH3_k127_1846_0	903818.KI912269_gene283	1.858e-167	539.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
WLSH3_k127_1846_3	644282.Deba_1534	6.462e-22	99.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH3_k127_2062869_0	868131.MSWAN_0325	2.133e-21	104.0	COG0392@1|root,arCOG00899@2157|Archaea,2XTI1@28890|Euryarchaeota,23NKG@183925|Methanobacteria	183925|Methanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH3_k127_2062869_1	311424.DhcVS_1244	5.031e-19	96.0	2EHX5@1|root,33BNR@2|Bacteria,2GATV@200795|Chloroflexi,34DBX@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2062869_2	1349785.BAUG01000036_gene1991	3.23e-05	51.0	COG3266@1|root,COG4886@1|root,COG3266@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia	976|Bacteroidetes	P	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4
WLSH3_k127_2129371_0	1124780.ANNU01000022_gene2963	1.763e-38	156.0	COG3677@1|root,COG3677@2|Bacteria,4NPDE@976|Bacteroidetes,47U28@768503|Cytophagia	976|Bacteroidetes	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,Transposase_mut
WLSH3_k127_2130184_0	391623.TERMP_00972	1.326e-49	181.0	COG0665@1|root,arCOG00755@2157|Archaea,2XTIF@28890|Euryarchaeota,242TA@183968|Thermococci	183968|Thermococci	C	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
WLSH3_k127_2130184_1	994573.T472_0206040	7.086e-41	168.0	2DTR7@1|root,33MCI@2|Bacteria,1W5BS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2130184_2	1128421.JAGA01000003_gene3265	1.131e-08	56.0	COG0266@1|root,COG0266@2|Bacteria,2NPGY@2323|unclassified Bacteria	2|Bacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WLSH3_k127_2141149_0	255470.cbdbA947	5.898e-203	647.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi,34CXP@301297|Dehalococcoidia	301297|Dehalococcoidia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WLSH3_k127_2141149_3	1128421.JAGA01000004_gene2588	3.907e-16	81.0	COG2740@1|root,COG2740@2|Bacteria,2NRZC@2323|unclassified Bacteria	2|Bacteria	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
WLSH3_k127_2141149_1	760568.Desku_2546	7.798e-117	391.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,2604E@186807|Peptococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WLSH3_k127_2141149_2	986075.CathTA2_1446	8.924e-61	216.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,4HC4S@91061|Bacilli	91061|Bacilli	C	carnitine dehydratase	amacr	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WLSH3_k127_2142855_3	1304880.JAGB01000002_gene1752	1.135e-95	319.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia	186801|Clostridia	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH3_k127_2142855_5	401526.TcarDRAFT_0274	1.033e-51	188.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,4H429@909932|Negativicutes	909932|Negativicutes	C	oxidoreductase gamma subunit	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WLSH3_k127_2142855_2	311424.DhcVS_1208	2.404e-128	418.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi,34D4Y@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	gcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WLSH3_k127_2142855_6	552811.Dehly_0414	2.681e-43	165.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi,34D1K@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTPase_1
WLSH3_k127_2142855_4	429009.Adeg_2015	3.99e-61	214.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
WLSH3_k127_2142855_1	429009.Adeg_1885	6.243e-239	753.0	COG1148@1|root,COG1148@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,42FJG@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
WLSH3_k127_2142855_0	1121472.AQWN01000006_gene1831	1.303e-278	880.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
WLSH3_k127_2145457_0	552811.Dehly_0299	4.089e-145	466.0	COG0014@1|root,COG0014@2|Bacteria,2G5TY@200795|Chloroflexi,34CYU@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH3_k127_2145457_4	1048834.TC41_2009	6.42e-08	61.0	COG0726@1|root,COG0726@2|Bacteria,1VNZ8@1239|Firmicutes	1239|Firmicutes	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2145457_2	266117.Rxyl_2997	8.195e-89	310.0	COG1541@1|root,COG1541@2|Bacteria	2|Bacteria	H	phenylacetate-CoA ligase activity	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
WLSH3_k127_2145457_1	234267.Acid_3566	4.41e-93	314.0	COG3823@1|root,COG3823@2|Bacteria,3Y4G6@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Glutamine cyclotransferase	-	-	2.3.2.5	ko:K00683	-	-	-	-	ko00000,ko01000	-	-	-	Glu_cyclase_2
WLSH3_k127_2145457_3	243164.DET0842	1.149e-67	235.0	COG0131@1|root,COG0131@2|Bacteria,2G6JA@200795|Chloroflexi,34D1H@301297|Dehalococcoidia	301297|Dehalococcoidia	E	imidazoleglycerol-phosphate dehydratase activity	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
WLSH3_k127_2471326_3	644282.Deba_2226	1.789e-23	101.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WLSH3_k127_2471326_1	335543.Sfum_1176	5.55e-104	350.0	COG0247@1|root,COG0247@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria,2MR23@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
WLSH3_k127_2471326_2	706587.Desti_4261	1.928e-48	177.0	COG1908@1|root,COG1908@2|Bacteria,1RCZY@1224|Proteobacteria	1224|Proteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
WLSH3_k127_2471326_0	1379698.RBG1_1C00001G0050	1.637e-146	478.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
WLSH3_k127_2499440_8	373903.Hore_14730	0.0001428	50.0	2BHTB@1|root,32BWZ@2|Bacteria,1VVE4@1239|Firmicutes,25109@186801|Clostridia,3WBTJ@53433|Halanaerobiales	186801|Clostridia	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
WLSH3_k127_2499440_5	797303.Natpe_0123	1.048e-17	93.0	arCOG06011@1|root,arCOG06011@2157|Archaea,2XXCS@28890|Euryarchaeota,23VSF@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
WLSH3_k127_2499440_1	311424.DhcVS_1130	6.981e-33	134.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi,34D3G@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
WLSH3_k127_2499440_2	997346.HMPREF9374_3164	1.403e-32	136.0	COG0084@1|root,COG0084@2|Bacteria,1TQUP@1239|Firmicutes,4HBEN@91061|Bacilli,27D2W@186824|Thermoactinomycetaceae	91061|Bacilli	L	TatD related DNase	M1-591	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WLSH3_k127_2499440_3	760568.Desku_2013	4.251e-30	122.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,262F8@186807|Peptococcaceae	186801|Clostridia	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH3_k127_2499440_4	552811.Dehly_1173	1.655e-20	96.0	COG1286@1|root,COG1286@2|Bacteria,2G9GY@200795|Chloroflexi,34CZ1@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
WLSH3_k127_2499440_6	497964.CfE428DRAFT_3496	1.638e-09	65.0	COG3871@1|root,COG3871@2|Bacteria,46VIW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
WLSH3_k127_2499440_0	374847.Kcr_0711	5.373e-67	232.0	COG0454@1|root,arCOG00826@2157|Archaea	2157|Archaea	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9,SCP2_2
WLSH3_k127_2499440_7	218491.ECA2152	5.898e-07	53.0	COG0500@1|root,COG2226@2|Bacteria,1R99I@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH3_k127_2565943_6	224325.AF_0563	8.376e-18	83.0	COG2044@1|root,arCOG02066@2157|Archaea,2XWA5@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM DsrE family protein	-	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,TusA
WLSH3_k127_2565943_8	386456.JQKN01000010_gene670	1.454e-15	79.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XSXC@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
WLSH3_k127_2565943_5	552811.Dehly_1605	6.437e-21	97.0	COG0640@1|root,COG0640@2|Bacteria,2GAVR@200795|Chloroflexi,34DFX@301297|Dehalococcoidia	301297|Dehalococcoidia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
WLSH3_k127_2565943_0	593750.Metfor_2724	1.197e-94	321.0	COG0701@1|root,arCOG02712@2157|Archaea,2XT2F@28890|Euryarchaeota,2NAE3@224756|Methanomicrobia	224756|Methanomicrobia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WLSH3_k127_2565943_4	552811.Dehly_1600	1.665e-22	99.0	COG0526@1|root,COG0526@2|Bacteria,2G7HI@200795|Chloroflexi,34DH0@301297|Dehalococcoidia	301297|Dehalococcoidia	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WLSH3_k127_2565943_7	646529.Desaci_1610	1.194e-16	86.0	COG4273@1|root,COG4273@2|Bacteria,1U4UX@1239|Firmicutes,257BY@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
WLSH3_k127_2565943_2	106370.Francci3_2325	7.574e-36	140.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4ET2T@85013|Frankiales	201174|Actinobacteria	T	low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WLSH3_k127_2565943_3	635013.TherJR_0461	3.442e-33	134.0	COG4871@1|root,COG4871@2|Bacteria,1V7YF@1239|Firmicutes,24KYS@186801|Clostridia,2630Z@186807|Peptococcaceae	186801|Clostridia	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS
WLSH3_k127_2565943_9	641143.HMPREF9331_01948	3.516e-13	76.0	2E9PV@1|root,333W7@2|Bacteria,4PJ10@976|Bacteroidetes,1I669@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2565943_1	1380384.JADN01000004_gene1900	3.307e-52	193.0	COG0785@1|root,COG0785@2|Bacteria,4PKGI@976|Bacteroidetes,1HYMT@117743|Flavobacteriia	976|Bacteroidetes	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
WLSH3_k127_2565943_11	1122176.KB903547_gene1098	1.356e-07	58.0	COG4733@1|root,COG4733@2|Bacteria,4PP23@976|Bacteroidetes,1J0XS@117747|Sphingobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WLSH3_k127_2579757_2	552811.Dehly_0539	1.048e-15	81.0	COG1938@1|root,COG1938@2|Bacteria,2GAS4@200795|Chloroflexi,34D7S@301297|Dehalococcoidia	301297|Dehalococcoidia	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
WLSH3_k127_2579757_0	255470.cbdbA950	7.87e-205	649.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,34CJQ@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH3_k127_2579757_1	743721.Psesu_2343	8.089e-22	96.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1X721@135614|Xanthomonadales	135614|Xanthomonadales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WLSH3_k127_258914_7	497964.CfE428DRAFT_1807	6.286e-25	111.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46UNM@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
WLSH3_k127_258914_1	552811.Dehly_0358	7.732e-104	348.0	COG0473@1|root,COG0473@2|Bacteria,2G68P@200795|Chloroflexi,34D3A@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WLSH3_k127_258914_3	243164.DET0449	5.231e-62	218.0	COG0066@1|root,COG0066@2|Bacteria,2G6PB@200795|Chloroflexi,34D8T@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
WLSH3_k127_258914_0	243164.DET0448	9.843e-181	574.0	COG0065@1|root,COG0065@2|Bacteria,2G5IZ@200795|Chloroflexi,34D6T@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WLSH3_k127_258914_2	311424.DhcVS_1485	3.872e-95	320.0	COG0294@1|root,COG0294@2|Bacteria,2G6A6@200795|Chloroflexi,34D72@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Pterin binding enzyme	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WLSH3_k127_258914_5	525904.Tter_0579	1.211e-51	188.0	COG0801@1|root,COG1469@1|root,COG0801@2|Bacteria,COG1469@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25	ko:K00950,ko:K09007,ko:K13940,ko:K17488	ko00790,ko01100,map00790,map01100	M00126,M00841	R00428,R03503,R03504,R04639,R05046,R05048,R10348	RC00002,RC00017,RC00263,RC00294,RC00323,RC00721,RC00943,RC00945,RC01188,RC02504,RC03131	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
WLSH3_k127_258914_6	552811.Dehly_1457	3.513e-35	138.0	COG0720@1|root,COG0720@2|Bacteria,2G7B6@200795|Chloroflexi,34DDV@301297|Dehalococcoidia	301297|Dehalococcoidia	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WLSH3_k127_258914_8	351160.RCIX1750	4.628e-20	90.0	COG2835@1|root,arCOG04124@2157|Archaea,2XZRS@28890|Euryarchaeota,2NA4S@224756|Methanomicrobia	224756|Methanomicrobia	S	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Trm112p
WLSH3_k127_258914_4	243164.DET0331	5.636e-61	220.0	COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi,34CPI@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WLSH3_k127_259199_0	880073.Calab_3043	5.297e-155	500.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WLSH3_k127_259199_1	880073.Calab_3044	2.541e-64	225.0	COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6
WLSH3_k127_2768557_6	1122609.AUGT01000009_gene3020	1.584e-05	57.0	COG3170@1|root,COG3170@2|Bacteria,2GJWK@201174|Actinobacteria,4DRNY@85009|Propionibacteriales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2768557_2	927658.AJUM01000022_gene1258	7.255e-87	297.0	2DKFZ@1|root,309D6@2|Bacteria,4PP8C@976|Bacteroidetes,2FZR5@200643|Bacteroidia,3XJRP@558415|Marinilabiliaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
WLSH3_k127_2768557_1	671143.DAMO_0053	3.039e-101	338.0	COG0421@1|root,COG0421@2|Bacteria,2NPMY@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
WLSH3_k127_2768557_3	1123376.AUIU01000013_gene1779	9.418e-36	140.0	COG1586@1|root,COG1586@2|Bacteria,3J15H@40117|Nitrospirae	40117|Nitrospirae	F	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speH	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
WLSH3_k127_2768557_0	243164.DET0578	3.708e-182	583.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi,34CKJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	lysyl-tRNA aminoacylation	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WLSH3_k127_2768557_4	469381.Dpep_2228	2.397e-30	124.0	COG0172@1|root,COG0172@2|Bacteria,3T9VY@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WLSH3_k127_2837033_0	311424.DhcVS_1095	2.362e-132	428.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi,34D83@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WLSH3_k127_2837033_1	255470.cbdbA547	1.58e-104	349.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WLSH3_k127_2837033_2	243164.DET0573	7.793e-50	183.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,34CV3@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WLSH3_k127_2940641_1	311424.DhcVS_617	1.789e-95	316.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi,34D07@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WLSH3_k127_2940641_2	748449.Halha_2029	1.113e-67	247.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WB91@53433|Halanaerobiales	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WLSH3_k127_2940641_0	867845.KI911784_gene431	6.771e-208	659.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,374WK@32061|Chloroflexia	32061|Chloroflexia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WLSH3_k127_2945204_6	243164.DET0846	5.769e-06	48.0	COG0124@1|root,COG0124@2|Bacteria,2G962@200795|Chloroflexi,34CX8@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
WLSH3_k127_2945204_1	477974.Daud_0619	2.097e-136	447.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,247N5@186801|Clostridia	186801|Clostridia	O	Membrane-bound serine protease (ClpP class)	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
WLSH3_k127_2945204_5	643648.Slip_0188	9.479e-17	83.0	COG1030@1|root,COG1030@2|Bacteria,1TR54@1239|Firmicutes,247N5@186801|Clostridia,42KMS@68298|Syntrophomonadaceae	186801|Clostridia	O	NfeD-like C-terminal, partner-binding	yqeZ	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
WLSH3_k127_2945204_2	643648.Slip_0187	2.821e-92	309.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,42K01@68298|Syntrophomonadaceae	186801|Clostridia	O	SPFH domain Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH3_k127_2945204_0	760568.Desku_1362	9.482e-248	775.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,260X7@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM methylmalonyl-CoA mutase N-terminal domain	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WLSH3_k127_2945204_4	1094508.Tsac_2166	8.497e-34	134.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,24HPI@186801|Clostridia,42GK9@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	mce	-	4.4.1.5,5.1.99.1	ko:K01759,ko:K05606	ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02530,R02765,R09979	RC00004,RC00740,RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
WLSH3_k127_2945204_3	760568.Desku_1363	1.641e-57	202.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,261QG@186807|Peptococcaceae	186801|Clostridia	I	methylmalonyl-CoA mutase C-terminal	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WLSH3_k127_2945204_7	332101.JIBU02000045_gene3349	0.0003525	44.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,36E5B@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WLSH3_k127_3016544_1	56780.SYN_02086	1.097e-94	326.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WLSH3_k127_3016544_0	255470.cbdbA1358	3.168e-260	809.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,34D7Q@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WLSH3_k127_3045596_0	416591.Tlet_1576	1.391e-56	206.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Abhydrolase_1,Abhydrolase_6
WLSH3_k127_3045596_1	410358.Mlab_1184	1.802e-51	194.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,2NAUF@224756|Methanomicrobia	224756|Methanomicrobia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH3_k127_3056715_5	1250232.JQNJ01000001_gene3058	1.478e-11	64.0	COG5002@1|root,COG5002@2|Bacteria,4NIS2@976|Bacteroidetes,1IKGB@117743|Flavobacteriia	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WLSH3_k127_3056715_3	309801.trd_1857	4.241e-17	83.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
WLSH3_k127_3056715_1	926550.CLDAP_16000	2.722e-98	327.0	COG0500@1|root,COG2226@2|Bacteria,2G7XP@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH3_k127_3056715_0	255470.cbdbA973	6.715e-116	387.0	COG0477@1|root,COG2814@2|Bacteria,2G9WN@200795|Chloroflexi,34DKS@301297|Dehalococcoidia	301297|Dehalococcoidia	EGP	LacY proton/sugar symporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_3056715_2	311424.DhcVS_781	2.19e-74	261.0	COG2211@1|root,COG2211@2|Bacteria,2G6WX@200795|Chloroflexi,34CJ4@301297|Dehalococcoidia	301297|Dehalococcoidia	G	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_3094631_1	311424.DhcVS_1515	2.129e-79	269.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi,34CW8@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT
WLSH3_k127_3094631_2	552811.Dehly_1373	1.436e-48	184.0	COG0457@1|root,COG0457@2|Bacteria,2G6Q2@200795|Chloroflexi,34CXC@301297|Dehalococcoidia	301297|Dehalococcoidia	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
WLSH3_k127_3094631_0	1160707.AJIK01000044_gene1708	5.242e-266	841.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli,26DNY@186818|Planococcaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH3_k127_3131313_2	1382356.JQMP01000003_gene1427	9.28e-96	321.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi,27XH9@189775|Thermomicrobia	189775|Thermomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WLSH3_k127_3131313_3	479434.Sthe_2653	1.65e-35	146.0	COG0682@1|root,COG0682@2|Bacteria,2G78M@200795|Chloroflexi,27XSN@189775|Thermomicrobia	189775|Thermomicrobia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH3_k127_3131313_0	552811.Dehly_0980	4.942e-151	495.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi,34CNY@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH3_k127_3131313_1	311424.DhcVS_835	7.78e-105	355.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi,34D8Z@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Uncharacterized protein family UPF0004	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
WLSH3_k127_3131313_4	1379698.RBG1_1C00001G0795	2.777e-16	80.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	CP_0257	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
WLSH3_k127_3131313_5	177437.HRM2_02740	2.538e-12	68.0	COG0370@1|root,COG0370@2|Bacteria,1QWMI@1224|Proteobacteria,43BSF@68525|delta/epsilon subdivisions,2X739@28221|Deltaproteobacteria,2MI8F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3243185_0	311424.DhcVS_61	3.402e-167	537.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,34CQ5@301297|Dehalococcoidia	301297|Dehalococcoidia	J	cysteinyl-tRNA aminoacylation	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
WLSH3_k127_3243185_4	552811.Dehly_0386	3.937e-46	170.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi,34DIT@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WLSH3_k127_3243185_1	552811.Dehly_0382	6.753e-147	472.0	COG0031@1|root,COG0031@2|Bacteria,2G5PG@200795|Chloroflexi,34CIG@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH3_k127_3243185_2	552811.Dehly_0131	1.761e-91	309.0	COG1045@1|root,COG1045@2|Bacteria,2G6DI@200795|Chloroflexi,34D9R@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
WLSH3_k127_3243185_5	1296415.JACC01000014_gene976	8.822e-19	91.0	COG0626@1|root,COG0626@2|Bacteria,4NF0Q@976|Bacteroidetes,1HXPE@117743|Flavobacteriia,2YHRW@290174|Aquimarina	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	metC	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
WLSH3_k127_3243185_3	1255043.TVNIR_2757	2.494e-46	177.0	COG4591@1|root,COG4591@2|Bacteria,1R1KM@1224|Proteobacteria,1T554@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH3_k127_3334218_2	429009.Adeg_1981	2.587e-41	156.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,42GDH@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
WLSH3_k127_3334218_0	243164.DET1188	3.565e-181	574.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2G63D@200795|Chloroflexi,34CNV@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
WLSH3_k127_3334218_1	935948.KE386495_gene1424	3.722e-60	213.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,42G01@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
WLSH3_k127_3334218_3	311424.DhcVS_969	4.825e-25	106.0	COG0826@1|root,COG0826@2|Bacteria,2GAVB@200795|Chloroflexi,34DF3@301297|Dehalococcoidia	301297|Dehalococcoidia	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3334218_4	311424.DhcVS_578	6.597e-21	93.0	2A4FI@1|root,30T3T@2|Bacteria,2GAZZ@200795|Chloroflexi,34DNV@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_339225_1	604354.TSIB_0718	7.756e-164	523.0	COG0477@1|root,arCOG00143@2157|Archaea,2Y8EH@28890|Euryarchaeota,245MX@183968|Thermococci	183968|Thermococci	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_339225_9	255470.cbdbA858	4.873e-29	119.0	COG1522@1|root,COG1522@2|Bacteria,2G9J3@200795|Chloroflexi,34DE8@301297|Dehalococcoidia	301297|Dehalococcoidia	K	TFIIE alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
WLSH3_k127_339225_2	243164.DET0628	8.943e-160	516.0	COG1509@1|root,COG1509@2|Bacteria,2GBVD@200795|Chloroflexi,34CXT@301297|Dehalococcoidia	301297|Dehalococcoidia	C	4Fe-4S single cluster domain	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_14,LAM_C,Radical_SAM
WLSH3_k127_339225_3	311424.DhcVS_570	1.006e-111	370.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,34CTK@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WLSH3_k127_339225_4	552811.Dehly_0996	4.701e-84	291.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,34CTK@301297|Dehalococcoidia	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WLSH3_k127_339225_8	552811.Dehly_0997	3.25e-34	137.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
WLSH3_k127_339225_5	255470.cbdbA365	4.873e-74	252.0	COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi,34CK4@301297|Dehalococcoidia	301297|Dehalococcoidia	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
WLSH3_k127_339225_6	255470.cbdbA364	3.688e-56	201.0	COG0237@1|root,COG0237@2|Bacteria,2GARS@200795|Chloroflexi,34D6Q@301297|Dehalococcoidia	301297|Dehalococcoidia	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
WLSH3_k127_339225_7	1382356.JQMP01000001_gene1264	1.51e-49	181.0	COG0717@1|root,COG0717@2|Bacteria,2G8PG@200795|Chloroflexi,27YDB@189775|Thermomicrobia	189775|Thermomicrobia	F	dUTPase	-	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WLSH3_k127_339225_0	660470.Theba_1003	1.136e-198	631.0	COG1032@1|root,COG1032@2|Bacteria,2GCAG@200918|Thermotogae	200918|Thermotogae	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
WLSH3_k127_3403108_0	1265505.ATUG01000002_gene1827	1.705e-103	344.0	COG0535@1|root,COG0535@2|Bacteria,1N6IN@1224|Proteobacteria,43BE9@68525|delta/epsilon subdivisions,2X6SR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3403108_1	545695.TREAZ_3182	3.988e-60	216.0	COG2227@1|root,COG2227@2|Bacteria,2J59U@203691|Spirochaetes	203691|Spirochaetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH3_k127_3409118_3	1321781.HMPREF1985_00635	1.168e-20	93.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4H3YJ@909932|Negativicutes	909932|Negativicutes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WLSH3_k127_3409118_1	1294142.CINTURNW_1192	4.63e-36	139.0	2DMPW@1|root,32SY6@2|Bacteria,1VAXG@1239|Firmicutes,24MNR@186801|Clostridia,36KF1@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
WLSH3_k127_3409118_0	986075.CathTA2_1529	2.37e-61	231.0	COG0683@1|root,COG0683@2|Bacteria,1V4XA@1239|Firmicutes,4HYGJ@91061|Bacilli	91061|Bacilli	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
WLSH3_k127_3409118_2	877455.Metbo_1499	1.937e-26	112.0	arCOG04820@1|root,arCOG04820@2157|Archaea,2XX4W@28890|Euryarchaeota	28890|Euryarchaeota	T	PFAM SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
WLSH3_k127_3431770_0	552811.Dehly_0673	2.384e-110	362.0	COG0473@1|root,COG0473@2|Bacteria,2G63C@200795|Chloroflexi,34CP7@301297|Dehalococcoidia	301297|Dehalococcoidia	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WLSH3_k127_3431770_2	756499.Desde_3370	6.561e-15	83.0	2E5YB@1|root,330N1@2|Bacteria,1VEVQ@1239|Firmicutes,24RVC@186801|Clostridia,26314@186807|Peptococcaceae	186801|Clostridia	S	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_ribbon_2
WLSH3_k127_3431770_3	391603.FBALC1_15302	2.31e-08	64.0	COG0346@1|root,COG0346@2|Bacteria,4NSWT@976|Bacteroidetes,1I4YP@117743|Flavobacteriia	976|Bacteroidetes	E	Glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WLSH3_k127_3431770_1	401526.TcarDRAFT_1987	3.897e-41	175.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,4H37A@909932|Negativicutes	909932|Negativicutes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
WLSH3_k127_3439767_0	706587.Desti_5304	3.231e-147	475.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_3439767_1	1071073.KI530537_gene2189	7.856e-94	319.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli,1ZPZV@1386|Bacillus	91061|Bacilli	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH3_k127_3477317_1	1121865.OMW_02130	7.403e-125	410.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,4HEF4@91061|Bacilli,4B0CM@81852|Enterococcaceae	91061|Bacilli	C	Na+-transporting oxaloacetate decarboxylase beta subunit	oadB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
WLSH3_k127_3477317_0	1121440.AUMA01000011_gene2309	0.0	1064.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2M7WE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
WLSH3_k127_3477317_2	1125863.JAFN01000001_gene1563	4.605e-54	198.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,42QTZ@68525|delta/epsilon subdivisions,2WMV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WLSH3_k127_3570609_1	552811.Dehly_0767	7.828e-34	135.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi,34CS2@301297|Dehalococcoidia	301297|Dehalococcoidia	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
WLSH3_k127_3570609_0	243164.DET0782	2.106e-88	303.0	COG0352@1|root,COG0352@2|Bacteria,2G6P0@200795|Chloroflexi,34D0T@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
WLSH3_k127_3570609_3	671143.DAMO_3098	4.805e-16	82.0	COG2331@1|root,COG2331@2|Bacteria,2NRJX@2323|unclassified Bacteria	2|Bacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH3_k127_3570609_4	479434.Sthe_1281	1.82e-10	67.0	COG2331@1|root,COG2331@2|Bacteria,2G795@200795|Chloroflexi,27YPR@189775|Thermomicrobia	189775|Thermomicrobia	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH3_k127_3570609_2	1220535.IMCC14465_09740	8.648e-18	84.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,4BP5Q@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH3_k127_3597525_1	552811.Dehly_0968	2.035e-62	222.0	COG2086@1|root,COG2086@2|Bacteria,2G72U@200795|Chloroflexi	200795|Chloroflexi	C	electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WLSH3_k127_3597525_0	1131462.DCF50_p1036	1.211e-83	289.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4,Fer4_6,Fer4_7
WLSH3_k127_3597525_2	693746.OBV_02220	3.43e-07	53.0	COG4927@1|root,COG4927@2|Bacteria,1TQGX@1239|Firmicutes,24AAX@186801|Clostridia	186801|Clostridia	S	Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
WLSH3_k127_3707147_0	515635.Dtur_0810	2.477e-164	528.0	COG0112@1|root,COG0112@2|Bacteria	2|Bacteria	E	glycine hydroxymethyltransferase activity	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081	SHMT
WLSH3_k127_3707147_1	243164.DET1401	1.077e-79	277.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,34D90@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
WLSH3_k127_3707147_2	2325.TKV_c09900	2.975e-05	49.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WLSH3_k127_3709516_3	457570.Nther_0409	2.602e-64	229.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia	186801|Clostridia	H	PFAM UBA THIF-type NAD FAD binding	moeB	-	-	-	-	-	-	-	-	-	-	-	ThiF
WLSH3_k127_3709516_6	272844.PAB3241	1.446e-06	53.0	COG1977@1|root,arCOG00536@2157|Archaea,2Y6GG@28890|Euryarchaeota,244HE@183968|Thermococci	183968|Thermococci	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WLSH3_k127_3709516_0	552811.Dehly_1471	3.754e-211	682.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi,34D0F@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Helicase_C,ResIII
WLSH3_k127_3709516_5	552811.Dehly_1472	3.626e-35	138.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi,34DAN@301297|Dehalococcoidia	301297|Dehalococcoidia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WLSH3_k127_3709516_2	255470.cbdbA279	4.053e-95	318.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi,34CK3@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WLSH3_k127_3709516_4	243164.DET0340	2.847e-37	145.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi,34DCV@301297|Dehalococcoidia	301297|Dehalococcoidia	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WLSH3_k127_3709516_1	255470.cbdbA281	1.621e-101	339.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,34CIZ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	mraW	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WLSH3_k127_3716110_1	1123376.AUIU01000014_gene688	9.687e-26	107.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH3_k127_3716110_0	439235.Dalk_3101	1.232e-70	260.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,42UB1@68525|delta/epsilon subdivisions,2WQ1B@28221|Deltaproteobacteria,2MNNK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH3_k127_3776747_1	552811.Dehly_1051	1.975e-60	217.0	COG1234@1|root,COG1234@2|Bacteria	2|Bacteria	L	tRNA 3'-trailer cleavage	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WLSH3_k127_3776747_2	2002.JOEQ01000005_gene3575	2.072e-16	83.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria,4EJUS@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
WLSH3_k127_3776747_0	880072.Desac_2420	2.928e-159	534.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MQ8R@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
WLSH3_k127_3794837_7	1125863.JAFN01000001_gene1977	6.69e-58	206.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH3_k127_3794837_9	1125863.JAFN01000001_gene1976	6.961e-33	134.0	COG1014@1|root,COG1014@2|Bacteria,1R8XG@1224|Proteobacteria,42NPD@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	oxidoreductase	oorC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WLSH3_k127_3794837_11	521045.Kole_0380	1.808e-15	78.0	COG1144@1|root,COG1144@2|Bacteria,2GD79@200918|Thermotogae	200918|Thermotogae	C	TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
WLSH3_k127_3794837_12	138119.DSY1306	4.452e-08	56.0	COG2801@1|root,COG2801@2|Bacteria,1UINX@1239|Firmicutes,24BC3@186801|Clostridia	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
WLSH3_k127_3794837_8	255470.cbdbA286	2.257e-56	201.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi,34CXD@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WLSH3_k127_3794837_0	243164.DET0345	0.0	1016.0	COG0209@1|root,COG1594@1|root,COG0209@2|Bacteria,COG1594@2|Bacteria,2G5PW@200795|Chloroflexi,34CT1@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
WLSH3_k127_3794837_4	311424.DhcVS_655	4.525e-128	425.0	COG0634@1|root,COG1102@1|root,COG2203@1|root,COG0634@2|Bacteria,COG1102@2|Bacteria,COG2203@2|Bacteria,2G6HX@200795|Chloroflexi,34D91@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	GAF_2,Pribosyltran
WLSH3_k127_3794837_5	696281.Desru_2414	1.246e-90	310.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,24EUD@186801|Clostridia,267G2@186807|Peptococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH3_k127_3794837_10	511051.CSE_09390	3.573e-22	98.0	2C539@1|root,33HA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3794837_3	243164.DET0831	7.169e-152	486.0	COG0059@1|root,COG0059@2|Bacteria,2G5NP@200795|Chloroflexi,34D0K@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
WLSH3_k127_3794837_6	255470.cbdbA812	2.723e-66	229.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi,34D5M@301297|Dehalococcoidia	301297|Dehalococcoidia	E	ACT domain	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
WLSH3_k127_3794837_2	311424.DhcVS_737	1.122e-243	764.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi,34CWN@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WLSH3_k127_3794837_1	311424.DhcVS_738	3.711e-251	784.0	COG0129@1|root,COG0129@2|Bacteria,2G5QW@200795|Chloroflexi,34CXK@301297|Dehalococcoidia	301297|Dehalococcoidia	EG	dihydroxy-acid dehydratase activity	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
WLSH3_k127_3794837_13	1121090.KB894723_gene3184	9.682e-08	56.0	COG5164@1|root,COG5164@2|Bacteria,1VFKD@1239|Firmicutes,4ISEA@91061|Bacilli,1ZS7Y@1386|Bacillus	91061|Bacilli	K	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
WLSH3_k127_3806872_2	1071073.KI530537_gene2303	6.723e-26	109.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli,1ZAPM@1386|Bacillus	91061|Bacilli	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WLSH3_k127_3806872_0	765420.OSCT_1549	1.858e-176	566.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,3771Y@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
WLSH3_k127_3806872_1	243164.DET1196	9.918e-144	464.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH3_k127_3975821_1	477974.Daud_0114	1.735e-73	254.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,260ED@186807|Peptococcaceae	186801|Clostridia	C	CO dehydrogenase acetyl-CoA synthase delta subunit	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
WLSH3_k127_3975821_0	477974.Daud_0113	1.648e-103	345.0	COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,266X2@186807|Peptococcaceae	186801|Clostridia	E	Pterin binding enzyme	acsE	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WLSH3_k127_3975821_4	439235.Dalk_3239	8.905e-28	121.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2MIIH@213118|Desulfobacterales	28221|Deltaproteobacteria	O	heat shock protein DnaJ domain protein	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
WLSH3_k127_3975821_2	1121430.JMLG01000026_gene2	1.466e-50	186.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	QU41_16170	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Peptidase_S15
WLSH3_k127_3975821_3	985054.JQEZ01000003_gene1509	2.795e-32	134.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_3977112_0	909663.KI867150_gene284	2.337e-121	405.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2MQ89@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
WLSH3_k127_4093164_0	552811.Dehly_0251	2.842e-130	428.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi,34D8A@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WLSH3_k127_4093164_1	311424.DhcVS_370	3.094e-97	323.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi,34CP6@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WLSH3_k127_4093164_2	483219.LILAB_06840	2.762e-14	75.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,42RIS@68525|delta/epsilon subdivisions,2WMWC@28221|Deltaproteobacteria,2Z1X2@29|Myxococcales	28221|Deltaproteobacteria	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
WLSH3_k127_411449_2	1125863.JAFN01000001_gene1977	8.321e-34	134.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH3_k127_411449_0	1125863.JAFN01000001_gene1978	1.107e-133	435.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH3_k127_411449_1	1385513.N780_11795	2.064e-48	189.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA0E@91061|Bacilli,2Y8UF@289201|Pontibacillus	91061|Bacilli	E	Saccharopine dehydrogenase	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WLSH3_k127_4185043_1	1000569.HMPREF1040_1150	1.285e-17	88.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4H4HK@909932|Negativicutes	909932|Negativicutes	G	Belongs to the phosphoglycerate mutase family	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WLSH3_k127_4185043_0	552811.Dehly_1421	2.308e-88	309.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi,34CWT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
WLSH3_k127_4187281_4	498761.HM1_3019	8.605e-36	137.0	COG0778@1|root,COG0778@2|Bacteria,1V4ZI@1239|Firmicutes,24BD0@186801|Clostridia	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_4187281_2	1087481.AGFX01000038_gene1426	2.145e-59	215.0	COG0491@1|root,COG0491@2|Bacteria,1V7R8@1239|Firmicutes,4HIQJ@91061|Bacilli,26W07@186822|Paenibacillaceae	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH3_k127_4187281_3	298655.KI912266_gene4614	2.126e-48	183.0	COG1028@1|root,COG1028@2|Bacteria,2IEMJ@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WLSH3_k127_4187281_0	309801.trd_0354	3.552e-133	437.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi,27Y2T@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH3_k127_4187281_6	868595.Desca_1246	2.45e-17	85.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,2630E@186807|Peptococcaceae	186801|Clostridia	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
WLSH3_k127_4187281_1	439235.Dalk_5191	1.114e-73	266.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MIWR@213118|Desulfobacterales	1224|Proteobacteria	C	PFAM CoA-binding domain protein	MA20_15065	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WLSH3_k127_4187281_5	552811.Dehly_1113	3.771e-31	124.0	COG0029@1|root,COG0029@2|Bacteria,2G5JM@200795|Chloroflexi,34D0E@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WLSH3_k127_4324431_2	622312.ROSEINA2194_04023	1.834e-16	89.0	2CHFB@1|root,30T97@2|Bacteria,1V5ED@1239|Firmicutes,24I9Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4324431_0	1041930.Mtc_0044	5.611e-94	324.0	COG0535@1|root,arCOG00941@2157|Archaea,2Y8D6@28890|Euryarchaeota,2NBHW@224756|Methanomicrobia	224756|Methanomicrobia	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
WLSH3_k127_4324431_4	243164.DET0084	0.0001273	45.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	xerD2	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
WLSH3_k127_4324431_1	555088.DealDRAFT_2538	7.725e-85	289.0	COG1960@1|root,COG1960@2|Bacteria,1V03D@1239|Firmicutes,24A8N@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
WLSH3_k127_4324431_3	243365.CV_3093	6.155e-12	70.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,2KQE0@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
WLSH3_k127_4413339_2	255470.cbdbA1328	3.539e-27	113.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,34D96@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH3_k127_4413339_1	552811.Dehly_1387	2.993e-43	166.0	COG1825@1|root,COG1825@2|Bacteria,2G6YX@200795|Chloroflexi,34CVT@301297|Dehalococcoidia	301297|Dehalococcoidia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WLSH3_k127_4413339_0	368407.Memar_1892	5.544e-59	211.0	COG2998@1|root,arCOG00229@2157|Archaea,2XUR9@28890|Euryarchaeota,2N9NW@224756|Methanomicrobia	224756|Methanomicrobia	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WLSH3_k127_4519909_0	309798.COPRO5265_0032	1.065e-77	277.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1UJ0B@1239|Firmicutes,25ESZ@186801|Clostridia,42J5S@68295|Thermoanaerobacterales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,PAS_3,PAS_4
WLSH3_k127_4519909_2	374847.Kcr_0666	3.922e-06	57.0	arCOG00385@1|root,arCOG03450@1|root,arCOG00385@2157|Archaea,arCOG03450@2157|Archaea	2157|Archaea	-	-	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	Big_2,DUF553
WLSH3_k127_4519909_1	255470.cbdbA732	5.675e-14	74.0	COG4359@1|root,COG4359@2|Bacteria,2GAJK@200795|Chloroflexi,34CJE@301297|Dehalococcoidia	301297|Dehalococcoidia	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.87	ko:K08966	ko00270,ko01100,map00270,map01100	M00034	R07394	RC02074	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
WLSH3_k127_4583416_1	485915.Dret_0421	5.854e-166	533.0	COG1148@1|root,COG1148@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria,2M898@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,FlpD,Pyr_redox_2
WLSH3_k127_4583416_2	335543.Sfum_0013	5.061e-113	383.0	COG0247@1|root,COG1908@1|root,COG0247@2|Bacteria,COG1908@2|Bacteria,1R8YC@1224|Proteobacteria,42NJW@68525|delta/epsilon subdivisions,2WIX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9,FlpD
WLSH3_k127_4583416_3	1047013.AQSP01000084_gene758	8.863e-88	299.0	COG0543@1|root,COG0543@2|Bacteria,2NNUA@2323|unclassified Bacteria	2|Bacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK_1	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WLSH3_k127_4583416_0	1047013.AQSP01000084_gene759	4.578e-204	645.0	COG0493@1|root,COG0493@2|Bacteria,2NNXN@2323|unclassified Bacteria	2|Bacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,Pyr_redox_2
WLSH3_k127_4583416_5	429009.Adeg_2015	4.342e-63	219.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
WLSH3_k127_4583416_4	909663.KI867150_gene1870	1.682e-69	240.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42U69@68525|delta/epsilon subdivisions,2WQJZ@28221|Deltaproteobacteria,2MS1Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase, 20 kDa subunit	hyhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
WLSH3_k127_4638354_1	552811.Dehly_0626	1.22e-116	380.0	COG1013@1|root,COG1013@2|Bacteria,2GBU3@200795|Chloroflexi,34CRD@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH3_k127_4638354_0	243164.DET0726	3.621e-160	514.0	COG0674@1|root,COG0674@2|Bacteria,2G5M1@200795|Chloroflexi,34CZQ@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Pyruvate:ferredoxin oxidoreductase core domain II	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH3_k127_4638354_3	552811.Dehly_0628	2.644e-36	139.0	COG1144@1|root,COG1144@2|Bacteria,2GAVK@200795|Chloroflexi,34DFQ@301297|Dehalococcoidia	301297|Dehalococcoidia	C	4Fe-4S dicluster domain	porD	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
WLSH3_k127_4638354_2	255470.cbdbB16	1.578e-58	208.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi,34CU3@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WLSH3_k127_4754041_3	335543.Sfum_2526	5.322e-84	289.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
WLSH3_k127_4754041_2	1121472.AQWN01000009_gene439	1.176e-172	548.0	COG2070@1|root,COG2070@2|Bacteria,1VTQJ@1239|Firmicutes,24ZN0@186801|Clostridia,26495@186807|Peptococcaceae	186801|Clostridia	S	FMN-dependent dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
WLSH3_k127_4754041_6	311424.DhcVS_1080	5.499e-35	136.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,34DCQ@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
WLSH3_k127_4754041_11	1121405.dsmv_3288	2.878e-26	113.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH3_k127_4754041_10	56780.SYN_00003	2.349e-27	113.0	COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,42XFV@68525|delta/epsilon subdivisions,2WT1V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
WLSH3_k127_4754041_15	573064.Mefer_0284	3.98e-08	62.0	COG0454@1|root,arCOG01354@1|root,arCOG00826@2157|Archaea,arCOG01354@2157|Archaea,2XXYN@28890|Euryarchaeota	28890|Euryarchaeota	K	PFAM GCN5-related N-acetyltransferase	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH3_k127_4754041_7	266117.Rxyl_0525	5.507e-33	134.0	COG1695@1|root,COG1695@2|Bacteria,2IFDN@201174|Actinobacteria,4CQDC@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WLSH3_k127_4754041_9	1123288.SOV_5c00900	1.744e-27	118.0	COG2020@1|root,COG2020@2|Bacteria,1V495@1239|Firmicutes	1239|Firmicutes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WLSH3_k127_4754041_13	1183377.Py04_0621	4.801e-16	84.0	COG2083@1|root,arCOG01921@2157|Archaea,2Y13G@28890|Euryarchaeota,244BU@183968|Thermococci	183968|Thermococci	S	Belongs to the UPF0216 family	-	-	-	ko:K09737	-	-	-	-	ko00000	-	-	-	DUF61
WLSH3_k127_4754041_8	591019.Shell_1292	3.62e-29	125.0	COG1394@1|root,arCOG04101@2157|Archaea,2XQM2@28889|Crenarchaeota	28889|Crenarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WLSH3_k127_4754041_0	591019.Shell_1301	1.341e-222	698.0	COG1156@1|root,arCOG00865@2157|Archaea,2XPKW@28889|Crenarchaeota	28889|Crenarchaeota	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WLSH3_k127_4754041_1	647113.Metok_1443	1.23e-211	673.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,23Q05@183939|Methanococci	183939|Methanococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
WLSH3_k127_4754041_16	457415.HMPREF1006_00913	2.435e-05	51.0	COG1436@1|root,COG1436@2|Bacteria,3TBEX@508458|Synergistetes	508458|Synergistetes	C	PFAM ATP synthase (F 14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
WLSH3_k127_4754041_12	339860.Msp_1137	5.957e-18	95.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,23NMG@183925|Methanobacteria	183925|Methanobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
WLSH3_k127_4754041_14	1183377.Py04_0330	4.156e-11	71.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,243A6@183968|Thermococci	183968|Thermococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
WLSH3_k127_4754041_5	399550.Smar_1175	1.506e-38	149.0	COG0636@1|root,arCOG02455@2157|Archaea,2XQQG@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM H transporting two-sector ATPase C subunit	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
WLSH3_k127_4754041_4	399550.Smar_1176	7.422e-43	164.0	COG1269@1|root,arCOG04138@2157|Archaea,2XQ7V@28889|Crenarchaeota	28889|Crenarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019899,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0045851,GO:0046034,GO:0046390,GO:0046483,GO:0046961,GO:0048878,GO:0050801,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
WLSH3_k127_4842238_2	794903.OPIT5_30055	8.27e-25	105.0	COG0304@1|root,COG0304@2|Bacteria,46V0S@74201|Verrucomicrobia,3K7MU@414999|Opitutae	414999|Opitutae	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH3_k127_4842238_0	1131269.AQVV01000003_gene707	7.653e-114	376.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	fabH1	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C,Thiolase_N
WLSH3_k127_4842238_3	485913.Krac_7647	3.39e-11	65.0	COG0828@1|root,COG0828@2|Bacteria,2G7EY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WLSH3_k127_4842238_1	552811.Dehly_0119	4.019e-36	142.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi,34DBW@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
WLSH3_k127_48469_1	429009.Adeg_2014	6.566e-51	183.0	COG1941@1|root,COG1941@2|Bacteria,1V21E@1239|Firmicutes,24GWD@186801|Clostridia,42HGR@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
WLSH3_k127_48469_0	909663.KI867150_gene1871	8.178e-193	608.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42N63@68525|delta/epsilon subdivisions,2WJPA@28221|Deltaproteobacteria,2MQRM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WLSH3_k127_5036008_3	311424.DhcVS_276	2.918e-60	218.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi,34D7X@301297|Dehalococcoidia	301297|Dehalococcoidia	J	tRNA nucleotidyltransferase domain 2 putative	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WLSH3_k127_5036008_0	311424.DhcVS_275	3.745e-127	422.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi,34CQF@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
WLSH3_k127_5036008_2	243164.DET0332	1.482e-61	227.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi,34CSD@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH3_k127_5036008_1	1382306.JNIM01000001_gene2525	4.061e-72	249.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi	200795|Chloroflexi	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WLSH3_k127_5066306_8	2325.TKV_c19890	8.253e-46	172.0	COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,42FJ0@68295|Thermoanaerobacterales	186801|Clostridia	C	Methylene-tetrahydrofolate reductase C terminal	metV	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
WLSH3_k127_5066306_1	1167006.UWK_03163	7.665e-128	417.0	COG0685@1|root,COG2069@1|root,COG0685@2|Bacteria,COG2069@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,2MIIA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
WLSH3_k127_5066306_9	1089553.Tph_c14980	2.414e-38	153.0	COG1456@1|root,COG1456@2|Bacteria,1UIEM@1239|Firmicutes,25EJY@186801|Clostridia,42GZB@68295|Thermoanaerobacterales	186801|Clostridia	C	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
WLSH3_k127_5066306_3	880073.Calab_2023	5.651e-88	330.0	COG0493@1|root,COG0493@2|Bacteria,2NNRI@2323|unclassified Bacteria	2|Bacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.17.1.9,1.4.1.13,1.4.1.14	ko:K00123,ko:K00266	ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230	-	R00093,R00114,R00248,R00519	RC00006,RC00010,RC02796,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_20,Fer4_7,Pyr_redox_2
WLSH3_k127_5066306_0	386456.JQKN01000009_gene1131	3.165e-262	856.0	COG0243@1|root,arCOG01492@2157|Archaea,2Y8AB@28890|Euryarchaeota	28890|Euryarchaeota	C	formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WLSH3_k127_5066306_7	255470.cbdbA385	1.883e-64	239.0	COG4585@1|root,COG4585@2|Bacteria,2G8Y6@200795|Chloroflexi,34CZ4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS
WLSH3_k127_5066306_6	552811.Dehly_1140	1.321e-65	235.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi,34CRB@301297|Dehalococcoidia	301297|Dehalococcoidia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH3_k127_5066306_13	96561.Dole_0886	2.691e-05	50.0	COG2204@1|root,COG2204@2|Bacteria,1N2Q1@1224|Proteobacteria,42UAG@68525|delta/epsilon subdivisions,2WQU8@28221|Deltaproteobacteria,2MKH3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH3_k127_5066306_4	1047013.AQSP01000096_gene2190	3.755e-73	261.0	COG2116@1|root,COG2116@2|Bacteria,2NPFS@2323|unclassified Bacteria	2|Bacteria	P	Formate/nitrite transporter	focA	GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015318,GO:0015499,GO:0015711,GO:0015718,GO:0015724,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K03459,ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.2,1.A.16.1.3,1.A.16.2	-	iB21_1397.B21_02346,iECBD_1354.ECBD_1196,iECB_1328.ECB_02384,iECD_1391.ECD_02384,iECIAI39_1322.ECIAI39_2632,iEcSMS35_1347.EcSMS35_2639,iSF_1195.SF0899,iS_1188.S0963	CBS,Form_Nir_trans
WLSH3_k127_5066306_2	1121396.KB893059_gene2792	4.208e-95	320.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,2MIIA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
WLSH3_k127_5066306_10	876269.ARWA01000001_gene2145	7.857e-36	151.0	COG0642@1|root,COG2972@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria,3N9SQ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
WLSH3_k127_5066306_12	1122919.KB905575_gene3453	1.591e-22	102.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HBSC@91061|Bacilli,26S4H@186822|Paenibacillaceae	91061|Bacilli	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	mprA3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_5066306_11	439235.Dalk_3262	2.719e-28	118.0	COG0745@1|root,COG0745@2|Bacteria,1RINR@1224|Proteobacteria,42T1R@68525|delta/epsilon subdivisions,2WPHY@28221|Deltaproteobacteria,2MK8T@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH3_k127_5066306_5	647113.Metok_0186	1.477e-70	248.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,23QA9@183939|Methanococci	183939|Methanococci	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Pyr_redox_2
WLSH3_k127_5137064_2	243164.DET1394	2.332e-115	379.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi,34D9J@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH3_k127_5137064_1	324602.Caur_3106	1.206e-121	405.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,375A1@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WLSH3_k127_5137064_4	243164.DET1396	2.729e-48	180.0	COG0344@1|root,COG0344@2|Bacteria,2G6U5@200795|Chloroflexi,34D23@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH3_k127_5137064_3	243164.DET1397	2.075e-88	306.0	COG0240@1|root,COG0240@2|Bacteria,2G5W5@200795|Chloroflexi,34CNA@301297|Dehalococcoidia	301297|Dehalococcoidia	I	glycerolipid metabolic process	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WLSH3_k127_5137064_0	401526.TcarDRAFT_1254	2.979e-127	416.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H28A@909932|Negativicutes	909932|Negativicutes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WLSH3_k127_5137064_5	1232410.KI421426_gene1402	3.476e-35	140.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42TAG@68525|delta/epsilon subdivisions,2WPRH@28221|Deltaproteobacteria,43SJK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH3_k127_5137064_6	479434.Sthe_1843	7.097e-23	102.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi,27YH5@189775|Thermomicrobia	189775|Thermomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH3_k127_5163125_4	696369.KI912183_gene1399	2.194e-13	72.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,2604R@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
WLSH3_k127_5163125_0	316274.Haur_4078	3.45e-244	781.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,37552@32061|Chloroflexia	32061|Chloroflexia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WLSH3_k127_5163125_2	1128421.JAGA01000002_gene1507	3.48e-33	133.0	COG0319@1|root,COG0319@2|Bacteria,2NQ2S@2323|unclassified Bacteria	2|Bacteria	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029	-	-	-	UPF0054
WLSH3_k127_5163125_3	909663.KI867149_gene3397	5.214e-32	126.0	COG4274@1|root,COG4274@2|Bacteria,1PUJQ@1224|Proteobacteria,42XN6@68525|delta/epsilon subdivisions,2WTHH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
WLSH3_k127_5163125_1	552811.Dehly_0061	2.708e-40	153.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,34D5Y@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
WLSH3_k127_5163125_5	255470.cbdbA1363	8.726e-09	57.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi,34D5Y@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
WLSH3_k127_522403_3	1120973.AQXL01000122_gene151	1.865e-17	85.0	COG2043@1|root,COG2043@2|Bacteria,1TT5P@1239|Firmicutes,4HFED@91061|Bacilli,2796U@186823|Alicyclobacillaceae	91061|Bacilli	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
WLSH3_k127_522403_7	797299.HALLA_00425	2.121e-11	76.0	arCOG06738@1|root,arCOG06738@2157|Archaea,2Y4TD@28890|Euryarchaeota,2400D@183963|Halobacteria	183963|Halobacteria	M	TIGRFAM parallel beta-helix	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CarboxypepD_reg
WLSH3_k127_522403_6	316067.Geob_3064	1.752e-11	78.0	COG0823@1|root,COG1520@1|root,COG3794@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	2.4.1.109,3.2.1.4	ko:K00728,ko:K01179,ko:K13669	ko00500,ko00514,ko00515,ko01100,map00500,map00514,map00515,map01100	-	R04072,R06200,R07620,R11307,R11308,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GH5,GH9,GT39,GT87	-	CHU_C,GT87,PD40,VCBS
WLSH3_k127_522403_4	502558.EGYY_09920	1.187e-13	85.0	COG4625@1|root,COG4625@2|Bacteria,2GWTB@201174|Actinobacteria	201174|Actinobacteria	S	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
WLSH3_k127_522403_5	1313172.YM304_21500	2.513e-12	80.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Flg_new,HYR
WLSH3_k127_522403_0	552811.Dehly_0463	1.843e-74	256.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,34D3R@301297|Dehalococcoidia	301297|Dehalococcoidia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
WLSH3_k127_522403_2	696281.Desru_0095	4.458e-28	116.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,262CP@186807|Peptococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
WLSH3_k127_522403_1	243164.DET0585	2.473e-50	193.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi,34CSC@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WLSH3_k127_523901_8	644966.Tmar_2261	8.08e-44	162.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WD8E@538999|Clostridiales incertae sedis	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WLSH3_k127_523901_5	1123279.ATUS01000002_gene199	6.48e-56	201.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,1J5P3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WLSH3_k127_523901_3	255470.cbdbA468	1.166e-65	233.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi,34CX3@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WLSH3_k127_523901_9	443143.GM18_0860	3.097e-39	149.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,43V08@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WLSH3_k127_523901_1	255470.cbdbA466	4.338e-89	302.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi,34CIJ@301297|Dehalococcoidia	301297|Dehalococcoidia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WLSH3_k127_523901_2	255470.cbdbA465	1.56e-67	236.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi,34CMS@301297|Dehalococcoidia	301297|Dehalococcoidia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WLSH3_k127_523901_6	255470.cbdbA464	1.518e-50	181.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi,34DAY@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WLSH3_k127_523901_7	1382306.JNIM01000001_gene3524	2.502e-46	169.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WLSH3_k127_523901_11	411474.COPEUT_02181	1.237e-15	77.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,24UGF@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WLSH3_k127_523901_10	387344.LVIS_1668	1.308e-30	121.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli,3F7CW@33958|Lactobacillaceae	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WLSH3_k127_523901_0	311424.DhcVS_438	1.816e-91	306.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi,34CJJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WLSH3_k127_523901_4	1123371.ATXH01000034_gene775	1.446e-58	208.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WLSH3_k127_5331645_1	264732.Moth_1905	7.128e-94	318.0	COG0620@1|root,COG0620@2|Bacteria,1V08M@1239|Firmicutes,24BMV@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5331645_0	909663.KI867150_gene2868	0.0	1038.0	COG0369@1|root,COG1151@2|Bacteria,1NRXN@1224|Proteobacteria,42Y5Y@68525|delta/epsilon subdivisions,2WUG6@28221|Deltaproteobacteria,2MSJ9@213462|Syntrophobacterales	2|Bacteria	P	Prismane/CO dehydrogenase family	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
WLSH3_k127_5336911_7	387631.Asulf_02272	0.0006811	46.0	arCOG04467@1|root,arCOG04467@2157|Archaea,2Y56M@28890|Euryarchaeota,247FT@183980|Archaeoglobi	183980|Archaeoglobi	H	Mo-molybdopterin cofactor metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5336911_1	269797.Mbar_A2729	1.408e-192	610.0	COG0607@1|root,arCOG00517@1|root,arCOG00517@2157|Archaea,arCOG02021@2157|Archaea,2XSV0@28890|Euryarchaeota,2N97K@224756|Methanomicrobia	224756|Methanomicrobia	P	Rhodanese-like domain	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
WLSH3_k127_5336911_4	879212.DespoDRAFT_03531	8.565e-34	141.0	COG0607@1|root,COG1633@1|root,COG0607@2|Bacteria,COG1633@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2MJ8M@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
WLSH3_k127_5336911_5	868131.MSWAN_2227	4.621e-32	128.0	COG2146@1|root,arCOG02852@2157|Archaea,2XUZH@28890|Euryarchaeota	28890|Euryarchaeota	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
WLSH3_k127_5336911_3	644282.Deba_0071	4.689e-48	179.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH3_k127_5336911_0	1041930.Mtc_1620	0.0	1017.0	COG2217@1|root,COG3350@1|root,arCOG01576@2157|Archaea,arCOG04507@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH3_k127_5336911_6	1235279.C772_00890	1.582e-29	123.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli,26EAK@186818|Planococcaceae	91061|Bacilli	P	E1-E2 ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH3_k127_5336911_2	255470.cbdbA911	1.485e-85	289.0	COG1633@1|root,COG1633@2|Bacteria,2GBUD@200795|Chloroflexi,34CTE@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Ferritin-like	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
WLSH3_k127_5378180_2	56780.SYN_00663	9.982e-62	218.0	COG1751@1|root,COG1751@2|Bacteria,1RBXI@1224|Proteobacteria,42R3D@68525|delta/epsilon subdivisions,2WMRV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pyruvate kinase, alpha/beta domain	-	-	-	ko:K09126	-	-	-	-	ko00000	-	-	-	PK_C
WLSH3_k127_5378180_0	342949.PNA2_0342	2.84e-71	246.0	COG1042@1|root,arCOG01338@2157|Archaea,2XXCA@28890|Euryarchaeota,2435P@183968|Thermococci	183968|Thermococci	C	ATP-grasp domain	-	-	6.2.1.13	ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5
WLSH3_k127_5378180_1	257310.BB1576	5.943e-68	243.0	COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2W07P@28216|Betaproteobacteria,3T6K8@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2,Succ_CoA_lig
WLSH3_k127_5428951_2	552811.Dehly_1143	9.367e-42	154.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi,34CK0@301297|Dehalococcoidia	301297|Dehalococcoidia	J	leucyl-tRNA aminoacylation	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1
WLSH3_k127_5428951_4	436308.Nmar_1413	2.844e-12	67.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5428951_1	479434.Sthe_2093	1.14e-145	476.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi,27XPN@189775|Thermomicrobia	189775|Thermomicrobia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH3_k127_5428951_0	243164.DET0441	1.515e-304	945.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,34CU7@301297|Dehalococcoidia	301297|Dehalococcoidia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WLSH3_k127_5428951_5	552811.Dehly_0786	4.698e-11	65.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	2.1.1.37	ko:K00558,ko:K13639,ko:K13640	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03000,ko03032,ko03036	-	-	-	DNA_methylase,MerR,MerR_1
WLSH3_k127_5428951_3	264732.Moth_0689	7.187e-26	112.0	COG2202@1|root,COG3437@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42JG8@68295|Thermoanaerobacterales	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_4,PAS_9,SBP_bac_3
WLSH3_k127_5484429_6	552811.Dehly_1323	9.837e-86	288.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi,34D3P@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WLSH3_k127_5484429_1	552811.Dehly_1322	4.419e-131	423.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi,34D5U@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WLSH3_k127_5484429_2	552811.Dehly_1321	6.393e-118	386.0	COG0581@1|root,COG0581@2|Bacteria,2G8M9@200795|Chloroflexi,34CY6@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH3_k127_5484429_3	552811.Dehly_1320	6.636e-110	364.0	COG0573@1|root,COG0573@2|Bacteria,2G6CV@200795|Chloroflexi,34CIM@301297|Dehalococcoidia	301297|Dehalococcoidia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH3_k127_5484429_5	552811.Dehly_1318	8.287e-92	310.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi,34D0R@301297|Dehalococcoidia	301297|Dehalococcoidia	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WLSH3_k127_5484429_0	552811.Dehly_1190	9.035e-217	688.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi,34D12@301297|Dehalococcoidia	301297|Dehalococcoidia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,sCache_like
WLSH3_k127_5484429_4	552811.Dehly_1189	1.438e-108	355.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,34D9D@301297|Dehalococcoidia	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_5585565_0	177437.HRM2_02740	1.121e-28	120.0	COG0370@1|root,COG0370@2|Bacteria,1QWMI@1224|Proteobacteria,43BSF@68525|delta/epsilon subdivisions,2X739@28221|Deltaproteobacteria,2MI8F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5585565_1	1304275.C41B8_14585	2.547e-21	106.0	COG0524@1|root,COG0524@2|Bacteria,1MV5B@1224|Proteobacteria,1RNVY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WLSH3_k127_5585565_2	1121354.AQUV01000001_gene1608	3.721e-06	53.0	COG1957@1|root,COG1957@2|Bacteria,2GP6N@201174|Actinobacteria,22K90@1653|Corynebacteriaceae	201174|Actinobacteria	F	nucleoside	iunH2	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
WLSH3_k127_5585950_4	1382306.JNIM01000001_gene1256	1.281e-11	66.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WLSH3_k127_5585950_3	255470.cbdbA399	1.461e-42	161.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi,34CPB@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WLSH3_k127_5585950_2	311424.DhcVS_386	4.47e-83	282.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi,34CQY@301297|Dehalococcoidia	301297|Dehalococcoidia	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WLSH3_k127_5585950_1	203119.Cthe_0621	2.611e-118	389.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia,3WHBV@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
WLSH3_k127_5585950_0	552811.Dehly_1331	2.483e-196	619.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi,34CKK@301297|Dehalococcoidia	301297|Dehalococcoidia	E	HMGL-like	-	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
WLSH3_k127_5586319_1	552811.Dehly_0405	1.871e-40	152.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,34DCQ@301297|Dehalococcoidia	200795|Chloroflexi	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
WLSH3_k127_5586319_0	552811.Dehly_0760	4.218e-276	860.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi,34D8B@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WLSH3_k127_5686757_1	410358.Mlab_0955	5.611e-120	394.0	COG0651@1|root,arCOG01537@2157|Archaea,2XU88@28890|Euryarchaeota,2NAW3@224756|Methanomicrobia	224756|Methanomicrobia	C	Proton-conducting membrane transporter	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
WLSH3_k127_5686757_6	679926.Mpet_1576	1.652e-20	94.0	arCOG05308@1|root,arCOG05308@2157|Archaea,2XZ9W@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5686757_3	673860.AciM339_1163	6.731e-71	242.0	COG3260@1|root,arCOG01553@2157|Archaea,2Y8IV@28890|Euryarchaeota,3F3AA@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Belongs to the complex I 20 kDa subunit family	-	-	1.12.7.2	ko:K18023	-	-	R00019	-	ko00000,ko01000	-	-	-	Oxidored_q6
WLSH3_k127_5686757_5	439481.Aboo_0674	1.044e-39	155.0	COG3262@1|root,arCOG01552@2157|Archaea,2XZQ4@28890|Euryarchaeota,3F31C@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.12.7.2	ko:K18017	-	-	R00019	-	ko00000,ko01000	-	-	-	Complex1_30kDa
WLSH3_k127_5686757_0	439481.Aboo_0675	1.482e-164	527.0	COG3261@1|root,arCOG01547@2157|Archaea,2Y7K6@28890|Euryarchaeota,3F32J@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.12.7.2	ko:K18016	-	-	R00019	-	ko00000,ko01000	-	-	-	Complex1_49kDa,NiFeSe_Hases
WLSH3_k127_5686757_2	673860.AciM339_1166	5.45e-99	334.0	COG0650@1|root,arCOG01545@2157|Archaea,2Y85A@28890|Euryarchaeota,3F2S3@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
WLSH3_k127_5686757_4	1343739.PAP_01230	4.203e-43	162.0	COG1143@1|root,arCOG01543@2157|Archaea,2XYQV@28890|Euryarchaeota,243ZU@183968|Thermococci	183968|Thermococci	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_7
WLSH3_k127_5686757_7	679926.Mpet_1563	2.051e-12	69.0	COG0680@1|root,arCOG04429@2157|Archaea,2Y0IM@28890|Euryarchaeota,2NBF7@224756|Methanomicrobia	224756|Methanomicrobia	O	Hydrogenase maturation protease	-	-	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WLSH3_k127_5702626_0	398512.JQKC01000048_gene358	1.382e-65	241.0	COG2133@1|root,COG3291@1|root,COG3979@1|root,COG4733@1|root,COG5184@1|root,COG5297@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3979@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5297@2|Bacteria,1TQ2T@1239|Firmicutes,24EP0@186801|Clostridia,3WI1H@541000|Ruminococcaceae	186801|Clostridia	MU	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Paired_CXXCH_1,fn3
WLSH3_k127_5702626_2	1288826.MSNKSG1_18644	5.441e-05	46.0	COG2963@1|root,COG2963@2|Bacteria,1MZ3D@1224|Proteobacteria,1S6K6@1236|Gammaproteobacteria,46BH3@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
WLSH3_k127_5702626_3	240015.ACP_2610	0.0003912	43.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve_3
WLSH3_k127_5702626_1	314264.ROS217_18817	3.219e-10	67.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2TXXE@28211|Alphaproteobacteria,46PFF@74030|Roseovarius	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WLSH3_k127_5883293_0	552811.Dehly_0746	9.303e-187	596.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,34CUX@301297|Dehalococcoidia	301297|Dehalococcoidia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WLSH3_k127_5883293_2	311424.DhcVS_909	2.09e-44	168.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi,34D8E@301297|Dehalococcoidia	301297|Dehalococcoidia	S	KH domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
WLSH3_k127_5883293_1	311424.DhcVS_910	3.587e-69	242.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi,34D1I@301297|Dehalococcoidia	301297|Dehalococcoidia	U	60Kd inner membrane protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
WLSH3_k127_591601_1	243164.DET0224	4.423e-128	421.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,34D9I@301297|Dehalococcoidia	301297|Dehalococcoidia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WLSH3_k127_591601_10	247490.KSU1_C0515	5.866e-12	69.0	COG1063@1|root,COG1063@2|Bacteria,2J2DX@203682|Planctomycetes	203682|Planctomycetes	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH3_k127_591601_4	1205680.CAKO01000037_gene1254	2.754e-94	316.0	COG3386@1|root,COG3386@2|Bacteria,1QN8Y@1224|Proteobacteria,2U82N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
WLSH3_k127_591601_0	247490.KSU1_C0515	4.878e-145	466.0	COG1063@1|root,COG1063@2|Bacteria,2J2DX@203682|Planctomycetes	203682|Planctomycetes	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WLSH3_k127_591601_2	247490.KSU1_C0516	1.076e-123	401.0	COG1830@1|root,COG1830@2|Bacteria,2J2PV@203682|Planctomycetes	203682|Planctomycetes	G	DeoC/LacD family aldolase	-	-	-	-	-	-	-	-	-	-	-	-	DeoC
WLSH3_k127_591601_9	273063.STK_24120	5.781e-22	108.0	COG0535@1|root,arCOG00938@2157|Archaea	2157|Archaea	P	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Radical_SAM,SPASM
WLSH3_k127_591601_3	255470.cbdbA486	1.004e-100	337.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi,34D2N@301297|Dehalococcoidia	301297|Dehalococcoidia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_591601_6	255470.cbdbA485	2.75e-68	245.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi,34CVU@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH3_k127_591601_5	552811.Dehly_1333	1.401e-89	302.0	COG1235@1|root,COG1235@2|Bacteria,2G9K1@200795|Chloroflexi,34CQD@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WLSH3_k127_591601_7	255470.cbdbA1229	7.529e-42	159.0	COG1546@1|root,COG1546@2|Bacteria,2G6U8@200795|Chloroflexi,34DCD@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
WLSH3_k127_5925406_3	255470.cbdbA1400	4.777e-18	85.0	COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi,34DI4@301297|Dehalococcoidia	301297|Dehalococcoidia	O	HupF/HypC family	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
WLSH3_k127_5925406_1	552811.Dehly_1412	5.952e-106	349.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,34CKT@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Hydrogenase formation hypA family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
WLSH3_k127_5925406_2	502558.EGYY_01690	3.457e-34	133.0	COG0409@1|root,COG0409@2|Bacteria,2GMHA@201174|Actinobacteria,4CUKQ@84998|Coriobacteriia	84998|Coriobacteriia	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
WLSH3_k127_5925406_0	311424.DhcVS_1217	1.525e-136	441.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,34CYH@301297|Dehalococcoidia	301297|Dehalococcoidia	O	AIR synthase related protein, C-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
WLSH3_k127_595305_5	552811.Dehly_1384	3.598e-18	89.0	COG1280@1|root,COG1280@2|Bacteria,2GBTY@200795|Chloroflexi,34CQW@301297|Dehalococcoidia	301297|Dehalococcoidia	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
WLSH3_k127_595305_4	255470.cbdbB11	6.809e-22	105.0	2A4CG@1|root,30SY4@2|Bacteria,2GAT0@200795|Chloroflexi,34DA6@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_595305_7	929558.SMGD1_1699	0.0007574	51.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2YMN3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	H	4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WLSH3_k127_595305_3	357808.RoseRS_4618	1.102e-32	137.0	COG1668@1|root,COG1668@2|Bacteria,2G76A@200795|Chloroflexi,3777A@32061|Chloroflexia	32061|Chloroflexia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
WLSH3_k127_595305_0	867845.KI911784_gene167	5.436e-87	299.0	COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi,376NC@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH3_k127_595305_2	706587.Desti_0651	1.264e-42	161.0	2EB22@1|root,3352W@2|Bacteria,1NE0W@1224|Proteobacteria,42VEE@68525|delta/epsilon subdivisions,2WRJF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_595305_1	706587.Desti_1731	6.031e-43	159.0	2C7QB@1|root,341QI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5968412_3	373903.Hore_22510	1.877e-19	95.0	2FHHE@1|root,349BF@2|Bacteria,1W18C@1239|Firmicutes,254D0@186801|Clostridia,3WC18@53433|Halanaerobiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5968412_2	243164.DET0445	5.328e-25	108.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi,34DDA@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH3_k127_5968412_1	552811.Dehly_0559	4.273e-207	652.0	COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi,34CUT@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WLSH3_k127_5968412_0	1382306.JNIM01000001_gene274	5.122e-212	673.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WLSH3_k127_6013182_6	456442.Mboo_2078	3.811e-20	98.0	COG2410@1|root,arCOG04409@2157|Archaea,2Y1Y7@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF429)	-	-	-	ko:K09147	-	-	-	-	ko00000	-	-	-	DUF429
WLSH3_k127_6013182_0	1209989.TepiRe1_2817	2.441e-163	526.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,42FH5@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
WLSH3_k127_6013182_2	1121430.JMLG01000036_gene165	4.414e-83	286.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,24944@186801|Clostridia,26211@186807|Peptococcaceae	186801|Clostridia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
WLSH3_k127_6013182_4	688269.Theth_0234	7.058e-50	182.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_6013182_7	342949.PNA2_0778	2.354e-05	48.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota,242IJ@183968|Thermococci	183968|Thermococci	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_6013182_1	255470.cbdbA801	3.809e-118	385.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi,34D7J@301297|Dehalococcoidia	301297|Dehalococcoidia	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
WLSH3_k127_6013182_3	243164.DET0823	4.064e-82	278.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi,34D7J@301297|Dehalococcoidia	301297|Dehalococcoidia	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
WLSH3_k127_6013182_5	515635.Dtur_1264	1.659e-20	93.0	COG1371@1|root,COG1371@2|Bacteria	2|Bacteria	J	PFAM Archease protein family (DUF101 UPF0211)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
WLSH3_k127_6044200_0	635013.TherJR_1036	1.959e-253	816.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH3_k127_6044200_2	28042.GU90_13100	1.693e-92	314.0	COG1801@1|root,COG1801@2|Bacteria,2HNT3@201174|Actinobacteria,4E0DV@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WLSH3_k127_6044200_3	1459636.NTE_03059	7.957e-13	69.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6044200_1	297246.lpp1602	1.777e-105	355.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RZ4V@1236|Gammaproteobacteria,1JFF1@118969|Legionellales	118969|Legionellales	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH3_k127_609283_1	1128421.JAGA01000002_gene104	7.079e-86	294.0	COG0598@1|root,COG0598@2|Bacteria,2NQIW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WLSH3_k127_609283_2	159450.NH14_28820	2.759e-32	132.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,2VN8Q@28216|Betaproteobacteria,1K0IY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
WLSH3_k127_609283_0	255470.cbdbA381	1.09e-96	322.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi,34CP6@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WLSH3_k127_609283_3	1118054.CAGW01000032_gene626	2.273e-08	56.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WLSH3_k127_6123424_0	909663.KI867150_gene1212	5.392e-172	546.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2MSIE@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_6123424_1	311424.DhcVS_643	4.586e-122	402.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi,34D24@301297|Dehalococcoidia	301297|Dehalococcoidia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WLSH3_k127_6162450_0	656519.Halsa_0550	1.478e-65	239.0	COG3210@1|root,COG3420@1|root,COG3210@2|Bacteria,COG3420@2|Bacteria,1UMKE@1239|Firmicutes,25GJU@186801|Clostridia,3WBRV@53433|Halanaerobiales	2|Bacteria	PU	Inverse autotransporter, beta-domain	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF285,Fil_haemagg,Fil_haemagg_2,Glug,Haemagg_act,SLH
WLSH3_k127_6162450_1	96561.Dole_2064	2.484e-15	78.0	COG1148@1|root,COG1148@2|Bacteria,1N26U@1224|Proteobacteria,43BRJ@68525|delta/epsilon subdivisions,2X72E@28221|Deltaproteobacteria,2MPJ6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH3_k127_6186572_2	56780.SYN_00286	8.477e-84	282.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2MRF6@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
WLSH3_k127_6186572_0	639282.DEFDS_1829	8.452e-135	437.0	COG2070@1|root,COG2070@2|Bacteria,2GF0W@200930|Deferribacteres	200930|Deferribacteres	C	IMP dehydrogenase / GMP reductase domain	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
WLSH3_k127_6186572_3	243164.DET0433	1.561e-49	184.0	2A4BY@1|root,30SXK@2|Bacteria,2GASQ@200795|Chloroflexi,34D9B@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6186572_1	552811.Dehly_1035	1.574e-94	321.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,34D5F@301297|Dehalococcoidia	301297|Dehalococcoidia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WLSH3_k127_6266292_1	660470.Theba_2261	2.114e-48	177.0	2DH26@1|root,2ZY4Z@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
WLSH3_k127_6266292_0	311424.DhcVS_1490	3.615e-174	561.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi,34D54@301297|Dehalococcoidia	301297|Dehalococcoidia	A	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WLSH3_k127_6266292_2	552811.Dehly_0010	4.933e-06	49.0	COG1692@1|root,COG1692@2|Bacteria,2GAP9@200795|Chloroflexi,34CYI@301297|Dehalococcoidia	301297|Dehalococcoidia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
WLSH3_k127_6294963_5	765420.OSCT_1271	1.047e-50	192.0	COG0616@1|root,COG0616@2|Bacteria,2G8IM@200795|Chloroflexi,3766H@32061|Chloroflexia	32061|Chloroflexia	OU	TIGRFAM signal peptide peptidase SppA, 36K type	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
WLSH3_k127_6294963_4	525904.Tter_0108	5.371e-60	218.0	COG0169@1|root,COG0169@2|Bacteria,2NPR3@2323|unclassified Bacteria	2|Bacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25,4.2.1.10	ko:K00014,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,Shikimate_DH,Shikimate_dh_N
WLSH3_k127_6294963_7	1408437.JNJN01000003_gene1591	8.262e-23	104.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,25X7S@186806|Eubacteriaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WLSH3_k127_6294963_0	255470.cbdbA65	4.714e-301	946.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi,34CVN@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WLSH3_k127_6294963_2	357808.RoseRS_2972	5.186e-133	433.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_6294963_3	316274.Haur_0958	6.483e-133	434.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi,3763W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_6294963_1	479434.Sthe_1003	3.583e-192	607.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi,27Y0Z@189775|Thermomicrobia	189775|Thermomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WLSH3_k127_6294963_6	477974.Daud_2174	4.788e-42	156.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,260AM@186807|Peptococcaceae	186801|Clostridia	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
WLSH3_k127_633965_1	1125863.JAFN01000001_gene1552	6.532e-102	348.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
WLSH3_k127_633965_0	706587.Desti_4264	3.626e-177	571.0	COG1148@1|root,COG1148@2|Bacteria,1PZ04@1224|Proteobacteria,42PT3@68525|delta/epsilon subdivisions,2WMJU@28221|Deltaproteobacteria,2MR5J@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
WLSH3_k127_633965_2	880073.Calab_3046	1.179e-99	330.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
WLSH3_k127_6351012_8	1125863.JAFN01000001_gene1978	1.432e-34	135.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH3_k127_6351012_7	374847.Kcr_0965	5.811e-43	173.0	COG1748@1|root,arCOG00243@2157|Archaea	2157|Archaea	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP,Semialdhyde_dh,UDPG_MGDP_dh_N
WLSH3_k127_6351012_0	3656.XP_008437552.1	1.354e-177	570.0	COG1012@1|root,KOG2451@2759|Eukaryota,37KPW@33090|Viridiplantae,3GA3J@35493|Streptophyta,4JMAG@91835|fabids	35493|Streptophyta	C	Dehydrogenase	-	GO:0003674,GO:0003824,GO:0003842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006536,GO:0006560,GO:0006562,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009507,GO:0009536,GO:0009628,GO:0009651,GO:0009987,GO:0010133,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019752,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0055114,GO:0071704,GO:0072593,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
WLSH3_k127_6351012_3	1487923.DP73_14175	3.188e-111	368.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,24BDQ@186801|Clostridia,261Z4@186807|Peptococcaceae	186801|Clostridia	S	Zn-dependent hydrolase, glyoxylase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH3_k127_6351012_5	565033.GACE_1498	6.824e-78	272.0	COG1145@1|root,arCOG02189@2157|Archaea,2Y1K1@28890|Euryarchaeota,246P5@183980|Archaeoglobi	183980|Archaeoglobi	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6351012_1	869210.Marky_0198	3.583e-118	390.0	COG1363@1|root,COG1363@2|Bacteria,1WJP2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	M42 glutamyl aminopeptidase	cel	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WLSH3_k127_6351012_2	1499967.BAYZ01000155_gene651	2.743e-113	374.0	COG0005@1|root,COG0005@2|Bacteria,2NNYQ@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
WLSH3_k127_6351012_4	311424.DhcVS_457	1.573e-100	338.0	COG0620@1|root,COG0620@2|Bacteria,2G8QD@200795|Chloroflexi,34D53@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6351012_6	1415774.U728_2985	5.707e-49	179.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,36I0M@31979|Clostridiaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WLSH3_k127_6351012_9	552811.Dehly_0663	7.926e-17	82.0	COG0009@1|root,COG0009@2|Bacteria,2G673@200795|Chloroflexi,34CQJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
WLSH3_k127_6380606_45	243164.DET0142	8.23e-21	92.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi,34D3P@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WLSH3_k127_6380606_9	439235.Dalk_1525	2.419e-120	393.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,42PAQ@68525|delta/epsilon subdivisions,2WKN9@28221|Deltaproteobacteria,2MKJR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM amidohydrolase 2	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
WLSH3_k127_6380606_20	1347392.CCEZ01000049_gene1505	5.719e-88	299.0	COG3173@1|root,COG3173@2|Bacteria,1U4B2@1239|Firmicutes,247PD@186801|Clostridia,36FQ5@31979|Clostridiaceae	186801|Clostridia	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH3_k127_6380606_40	1227487.C474_21006	1.672e-32	135.0	arCOG03919@1|root,arCOG03919@2157|Archaea,2XUDK@28890|Euryarchaeota,23TJR@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NicO
WLSH3_k127_6380606_52	502558.EGYY_00210	0.0004212	53.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria,4CVU5@84998|Coriobacteriia	84998|Coriobacteriia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WLSH3_k127_6380606_4	1173023.KE650771_gene2934	4.411e-159	515.0	COG1012@1|root,COG1012@2|Bacteria,1G09W@1117|Cyanobacteria,1JHZW@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH3_k127_6380606_24	1499967.BAYZ01000005_gene5442	8.898e-76	260.0	COG0145@1|root,COG0145@2|Bacteria	2|Bacteria	EQ	ligase activity	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0266c	DUF1638,Hydant_A_N,Hydantoinase_A,Hydantoinase_B
WLSH3_k127_6380606_28	1499967.BAYZ01000005_gene5444	1.044e-68	239.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
WLSH3_k127_6380606_25	1499967.BAYZ01000005_gene5443	8.48e-75	258.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,SBP_bac_1,SBP_bac_8,UTRA
WLSH3_k127_6380606_49	1082933.MEA186_11436	7.48e-11	74.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria,43GWM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH3_k127_6380606_34	358220.C380_17375	1.186e-45	176.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2VHAJ@28216|Betaproteobacteria,4AB5H@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH3_k127_6380606_30	1038862.KB893806_gene2885	1.264e-58	216.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,3JWJH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	MA20_29500	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
WLSH3_k127_6380606_26	1125863.JAFN01000001_gene1062	1.6e-72	252.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WLSH3_k127_6380606_21	1125863.JAFN01000001_gene1061	3.096e-83	284.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42MSC@68525|delta/epsilon subdivisions,2WJAH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WLSH3_k127_6380606_6	439235.Dalk_4476	3.006e-156	513.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42PUP@68525|delta/epsilon subdivisions,2WMAH@28221|Deltaproteobacteria,2MN7Y@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH3_k127_6380606_32	909663.KI867150_gene2416	1.813e-52	194.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,42QH3@68525|delta/epsilon subdivisions,2WKXH@28221|Deltaproteobacteria,2MRW2@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WLSH3_k127_6380606_48	1499967.BAYZ01000076_gene805	1.048e-12	76.0	2DS8H@1|root,32USH@2|Bacteria	2|Bacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
WLSH3_k127_6380606_27	1499967.BAYZ01000005_gene5439	5.874e-70	242.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WLSH3_k127_6380606_44	264732.Moth_1314	3.305e-27	115.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
WLSH3_k127_6380606_7	1121468.AUBR01000019_gene2662	7.11e-132	428.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
WLSH3_k127_6380606_42	706587.Desti_5496	6.526e-29	124.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
WLSH3_k127_6380606_3	177437.HRM2_38950	1.386e-167	546.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,2MPY1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WLSH3_k127_6380606_18	768706.Desor_3513	1.563e-88	300.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
WLSH3_k127_6380606_2	1121405.dsmv_0897	2.076e-192	622.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
WLSH3_k127_6380606_33	1121447.JONL01000009_gene2662	5.612e-51	194.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,42MVD@68525|delta/epsilon subdivisions,2WIY3@28221|Deltaproteobacteria,2M8E8@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
WLSH3_k127_6380606_36	255470.cbdbA646	3.125e-43	172.0	COG4585@1|root,COG4585@2|Bacteria,2G8PE@200795|Chloroflexi,34CQA@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WLSH3_k127_6380606_31	552811.Dehly_1140	4.513e-56	204.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi,34CRB@301297|Dehalococcoidia	301297|Dehalococcoidia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH3_k127_6380606_51	1189612.A33Q_2665	1.013e-05	58.0	COG5492@1|root,COG5492@2|Bacteria,4NH7Q@976|Bacteroidetes,47MBP@768503|Cytophagia	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	TIG
WLSH3_k127_6380606_43	909663.KI867150_gene322	1.588e-28	130.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,42MVD@68525|delta/epsilon subdivisions,2WIY3@28221|Deltaproteobacteria,2MR71@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
WLSH3_k127_6380606_50	1121413.JMKT01000009_gene2087	1.685e-07	61.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
WLSH3_k127_6380606_12	1499967.BAYZ01000093_gene4021	6.127e-113	381.0	COG1593@1|root,COG1593@2|Bacteria	2|Bacteria	G	mannitol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DctM
WLSH3_k127_6380606_11	1125863.JAFN01000001_gene1352	3.494e-118	396.0	COG0043@1|root,COG0043@2|Bacteria,1PZMY@1224|Proteobacteria,42RNW@68525|delta/epsilon subdivisions,2WNJN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
WLSH3_k127_6380606_29	767817.Desgi_2402	1.521e-68	237.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,261IS@186807|Peptococcaceae	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
WLSH3_k127_6380606_47	304371.MCP_1913	3.66e-14	77.0	arCOG04966@1|root,arCOG04966@2157|Archaea,2Y1AU@28890|Euryarchaeota,2NA66@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6380606_17	224325.AF_1207	3.35e-91	306.0	COG1028@1|root,arCOG01259@2157|Archaea,2XSWX@28890|Euryarchaeota,2469N@183980|Archaeoglobi	183980|Archaeoglobi	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059,ko:K07535	ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220	M00083,M00540,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05582,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00154	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH3_k127_6380606_1	768706.Desor_2360	3.583e-196	616.0	COG1878@1|root,COG1878@2|Bacteria,1TT6T@1239|Firmicutes,24CVX@186801|Clostridia	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
WLSH3_k127_6380606_39	1511.CLOST_0194	1.197e-37	144.0	COG3257@1|root,COG3257@2|Bacteria,1V6Z0@1239|Firmicutes,24K39@186801|Clostridia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH3_k127_6380606_16	903818.KI912268_gene2109	1.084e-94	320.0	COG1250@1|root,COG1250@2|Bacteria,3Y3S5@57723|Acidobacteria	57723|Acidobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WLSH3_k127_6380606_10	383372.Rcas_2297	2.505e-120	393.0	COG3246@1|root,COG3246@2|Bacteria,2G81V@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:Kce	-	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
WLSH3_k127_6380606_46	1365176.N186_06370	1.901e-14	81.0	COG1618@1|root,arCOG01034@2157|Archaea,2XR6D@28889|Crenarchaeota	28889|Crenarchaeota	F	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
WLSH3_k127_6380606_35	243164.DET0100	4.631e-44	169.0	2DDUA@1|root,2ZJB8@2|Bacteria,2GBVN@200795|Chloroflexi,34CYW@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6380606_0	903818.KI912268_gene600	0.0	1221.0	COG0243@1|root,COG0243@2|Bacteria,3Y2IU@57723|Acidobacteria	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.2.3	ko:K07812	-	-	-	-	ko00000,ko01000,ko02000	5.A.3.4	-	-	Molybdopterin,Molydop_binding
WLSH3_k127_6380606_23	1089553.Tph_c01440	8.312e-76	263.0	COG0437@1|root,COG0437@2|Bacteria,1V55Z@1239|Firmicutes,24I9I@186801|Clostridia	186801|Clostridia	C	Similarity to COG0437 Fe-S-cluster-containing hydrogenase components 1(Evalue	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Fer4_11
WLSH3_k127_6380606_8	903818.KI912268_gene1018	1.993e-126	418.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,TAT_signal
WLSH3_k127_6380606_22	903818.KI912268_gene2316	9.254e-80	273.0	COG0411@1|root,COG0411@2|Bacteria,3Y9E1@57723|Acidobacteria	2|Bacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WLSH3_k127_6380606_19	903818.KI912268_gene2315	2.304e-88	297.0	COG0410@1|root,COG0410@2|Bacteria,3Y9ED@57723|Acidobacteria	57723|Acidobacteria	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH3_k127_6380606_15	903818.KI912268_gene1022	6.154e-99	330.0	COG0559@1|root,COG0559@2|Bacteria	2|Bacteria	E	leucine import across plasma membrane	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH3_k127_6380606_14	903818.KI912268_gene1023	9.941e-107	355.0	COG4177@1|root,COG4177@2|Bacteria	2|Bacteria	E	L-phenylalanine transmembrane transporter activity	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH3_k127_6380606_5	552811.Dehly_1187	2.782e-157	506.0	COG0592@1|root,COG0592@2|Bacteria,2GBVX@200795|Chloroflexi,34D0Q@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol3_beta_2,DNA_pol3_beta_3
WLSH3_k127_6380606_38	311424.DhcVS_247	1.597e-38	154.0	COG1595@1|root,COG1595@2|Bacteria,2G9W0@200795|Chloroflexi,34DH9@301297|Dehalococcoidia	301297|Dehalococcoidia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6380606_13	273068.TTE0252	8.95e-113	376.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,42EST@68295|Thermoanaerobacterales	186801|Clostridia	C	decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
WLSH3_k127_6380606_41	243164.DET1607	1.288e-30	126.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,34D0G@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WLSH3_k127_6381406_1	525904.Tter_0805	1.104e-150	487.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WLSH3_k127_6381406_2	1112217.PPL19_07066	1.104e-06	50.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	-	ko:K01663,ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iYL1228.KPN_02481	His_biosynth
WLSH3_k127_6381406_0	697281.Mahau_0316	2.01e-197	622.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,42FA1@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WLSH3_k127_6419040_3	439235.Dalk_5191	3.95e-71	256.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MIWR@213118|Desulfobacterales	1224|Proteobacteria	C	PFAM CoA-binding domain protein	MA20_15065	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WLSH3_k127_6419040_1	439235.Dalk_2665	2.418e-100	339.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_6419040_2	439235.Dalk_4173	4.497e-99	337.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,42ZRT@68525|delta/epsilon subdivisions,2WUTK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_6419040_0	555088.DealDRAFT_2004	9.959e-137	456.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42KZ3@68298|Syntrophomonadaceae	186801|Clostridia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH3_k127_6419040_4	485913.Krac_2496	1.018e-69	241.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH3_k127_6446308_8	797299.HALLA_08105	4.283e-12	75.0	COG0529@1|root,arCOG01040@2157|Archaea,2XWW4@28890|Euryarchaeota,23V8B@183963|Halobacteria	183963|Halobacteria	P	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33
WLSH3_k127_6446308_5	748449.Halha_0981	5.056e-38	154.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,3WBHR@53433|Halanaerobiales	186801|Clostridia	S	DNA polymerase alpha chain like domain	trpH	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
WLSH3_k127_6446308_0	311424.DhcVS_454	5.91e-184	583.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi,34D4C@301297|Dehalococcoidia	301297|Dehalococcoidia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WLSH3_k127_6446308_2	370438.PTH_2759	1.162e-163	524.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,2608H@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WLSH3_k127_6446308_1	311424.DhcVS_1471	1.516e-168	537.0	COG0501@1|root,COG0501@2|Bacteria,2G6UV@200795|Chloroflexi,34D0W@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
WLSH3_k127_6446308_3	552811.Dehly_1171	2.218e-78	265.0	COG1704@1|root,COG1704@2|Bacteria,2GAPS@200795|Chloroflexi,34D06@301297|Dehalococcoidia	301297|Dehalococcoidia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WLSH3_k127_6446308_7	243164.DET1585	5.049e-27	115.0	COG3809@1|root,COG3809@2|Bacteria,2GAUV@200795|Chloroflexi,34DEB@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
WLSH3_k127_6446308_4	511051.CSE_06630	5.624e-41	175.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF4091,DUF4114,PPC,Peptidase_C2,SASA
WLSH3_k127_6446308_6	383372.Rcas_2295	8.03e-32	136.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
WLSH3_k127_676563_2	1291050.JAGE01000002_gene3639	4.141e-32	129.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,3WK48@541000|Ruminococcaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
WLSH3_k127_676563_1	316067.Geob_1166	9.561e-44	165.0	COG2050@1|root,COG2050@2|Bacteria,1N61W@1224|Proteobacteria,42U4S@68525|delta/epsilon subdivisions,2WQWD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WLSH3_k127_676563_0	1461580.CCAS010000037_gene3098	9.493e-71	248.0	COG2021@1|root,COG2021@2|Bacteria,1V0J9@1239|Firmicutes,4HCZZ@91061|Bacilli,1ZSGS@1386|Bacillus	91061|Bacilli	E	alpha/beta hydrolase fold	estA3	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WLSH3_k127_676563_3	1237149.C900_03515	2.507e-27	119.0	2E10Y@1|root,32WGY@2|Bacteria,4NTDG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6790912_2	357808.RoseRS_0692	2.346e-38	147.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH3_k127_6790912_0	479434.Sthe_1588	1.773e-66	255.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,27XNH@189775|Thermomicrobia	189775|Thermomicrobia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
WLSH3_k127_6790912_1	357808.RoseRS_3160	1.218e-65	241.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,374YS@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WLSH3_k127_6926013_0	1121468.AUBR01000056_gene1498	5.122e-72	256.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,42G7V@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,Peptidase_S8,SLH
WLSH3_k127_6926013_3	1158292.JPOE01000005_gene100	6.979e-17	89.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,1KK2V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH3_k127_6926013_1	909663.KI867150_gene1508	7.262e-63	226.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,2MRP7@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WLSH3_k127_6926013_2	909663.KI867150_gene1507	1.84e-21	96.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42RWX@68525|delta/epsilon subdivisions,2WNC9@28221|Deltaproteobacteria,2MRP7@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	yjiL	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WLSH3_k127_7086362_0	555088.DealDRAFT_1548	1.812e-63	226.0	COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,24DU6@186801|Clostridia,42KKD@68298|Syntrophomonadaceae	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
WLSH3_k127_7086362_1	552811.Dehly_1310	2.762e-46	173.0	COG0705@1|root,COG0705@2|Bacteria,2GAK1@200795|Chloroflexi,34CKZ@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WLSH3_k127_7086362_4	555779.Dthio_PD3008	3.814e-20	93.0	COG1598@1|root,COG1598@2|Bacteria,1NF1P@1224|Proteobacteria,431JK@68525|delta/epsilon subdivisions,2WWMT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7086362_2	192952.MM_2607	3.096e-34	134.0	COG2361@1|root,arCOG05024@2157|Archaea,2XYV1@28890|Euryarchaeota,2NBBR@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
WLSH3_k127_7086362_3	269797.Mbar_A0444	2.706e-28	116.0	COG1669@1|root,arCOG01206@2157|Archaea,2Y29X@28890|Euryarchaeota,2NBBA@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
WLSH3_k127_7120511_2	429009.Adeg_2058	7.812e-31	123.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,24JM5@186801|Clostridia,42G92@68295|Thermoanaerobacterales	186801|Clostridia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WLSH3_k127_7120511_3	1382306.JNIM01000001_gene1619	1.799e-29	121.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WLSH3_k127_7120511_1	255470.cbdbA339	9.042e-219	694.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi,34CIN@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WLSH3_k127_7120511_0	552811.Dehly_1271	4.829e-240	753.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi,34D7N@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
WLSH3_k127_7120511_4	255470.cbdbA332	4.346e-13	71.0	2BPGZ@1|root,32I9C@2|Bacteria,2G9VY@200795|Chloroflexi,34DH4@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7159223_7	756499.Desde_3001	8.497e-10	64.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,261QI@186807|Peptococcaceae	186801|Clostridia	C	FeS cluster assembly scaffold protein NifU	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WLSH3_k127_7159223_1	429009.Adeg_0423	2.797e-154	496.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WLSH3_k127_7159223_4	234267.Acid_6492	6.199e-47	173.0	COG1832@1|root,COG1832@2|Bacteria,3Y566@57723|Acidobacteria	57723|Acidobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WLSH3_k127_7159223_0	552811.Dehly_0247	5.222e-164	523.0	COG0309@1|root,COG0309@2|Bacteria,2G7TM@200795|Chloroflexi,34CX4@301297|Dehalococcoidia	301297|Dehalococcoidia	O	AIR synthase related protein, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C
WLSH3_k127_7159223_3	1232410.KI421413_gene766	1.895e-83	284.0	COG1145@1|root,COG1145@2|Bacteria,1PW12@1224|Proteobacteria,42MZ9@68525|delta/epsilon subdivisions,2WN0W@28221|Deltaproteobacteria,43SWA@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
WLSH3_k127_7159223_6	1120959.ATXF01000008_gene596	1.882e-12	76.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4FNQ6@85023|Microbacteriaceae	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WLSH3_k127_7159223_5	456442.Mboo_2130	1.334e-31	132.0	arCOG08014@1|root,arCOG08014@2157|Archaea,2Y5ZS@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7159223_2	935948.KE386495_gene2114	8.596e-136	438.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WLSH3_k127_7212447_1	868595.Desca_0702	9.333e-53	195.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25ZY5@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH3_k127_7212447_3	311424.DhcVS_17	5.33e-29	119.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi,34DFF@301297|Dehalococcoidia	301297|Dehalococcoidia	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7212447_2	411467.BACCAP_03261	4.663e-52	190.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WLSH3_k127_7212447_0	243164.DET0791	1.678e-211	670.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi,34D5C@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
WLSH3_k127_7282994_9	604354.TSIB_1439	0.0003671	48.0	COG1504@1|root,arCOG04337@2157|Archaea,2Y0P5@28890|Euryarchaeota,244CF@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
WLSH3_k127_7282994_8	631362.Thi970DRAFT_01063	7.716e-10	68.0	COG1198@1|root,COG1198@2|Bacteria	2|Bacteria	L	DNA replication, synthesis of RNA primer	-	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DZR,zf-ribbon_3,zinc_ribbon_2
WLSH3_k127_7282994_0	243164.DET0612	6.99e-186	590.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi,34CU0@301297|Dehalococcoidia	301297|Dehalococcoidia	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
WLSH3_k127_7282994_3	243164.DET0611	1.526e-62	221.0	COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi,34CYS@301297|Dehalococcoidia	301297|Dehalococcoidia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WLSH3_k127_7282994_7	1111479.AXAR01000005_gene565	2.869e-14	81.0	COG0500@1|root,COG2226@2|Bacteria,1VD84@1239|Firmicutes,4HKDK@91061|Bacilli,27AHP@186823|Alicyclobacillaceae	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
WLSH3_k127_7282994_2	311424.DhcVS_1162	3.634e-144	494.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,34CT3@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HD,HisKA_7TM
WLSH3_k127_7282994_1	243164.DET1379	2.015e-147	486.0	COG1541@1|root,COG1541@2|Bacteria,2GAKM@200795|Chloroflexi,34CP4@301297|Dehalococcoidia	301297|Dehalococcoidia	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
WLSH3_k127_7282994_5	243164.DET1377	6.776e-21	95.0	2A3IM@1|root,30S1K@2|Bacteria,2G9W1@200795|Chloroflexi,34DHC@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7282994_4	552811.Dehly_1107	2.977e-26	110.0	COG3432@1|root,COG3432@2|Bacteria,2GAUZ@200795|Chloroflexi,34DEJ@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_45
WLSH3_k127_729334_10	335543.Sfum_2526	3.934e-05	46.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
WLSH3_k127_729334_4	1121422.AUMW01000020_gene1740	9.65e-52	197.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	1.1.5.3	ko:K00113,ko:K21834	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,DrsE,Fer4_8
WLSH3_k127_729334_9	552811.Dehly_1395	1.065e-05	52.0	COG0789@1|root,COG0789@2|Bacteria,2GATA@200795|Chloroflexi,34DAP@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
WLSH3_k127_729334_5	1382306.JNIM01000001_gene3932	1.867e-50	186.0	COG0664@1|root,COG0664@2|Bacteria,2G6XU@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WLSH3_k127_729334_7	545695.TREAZ_0476	4.277e-08	57.0	COG1145@1|root,COG1145@2|Bacteria,2J684@203691|Spirochaetes	203691|Spirochaetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
WLSH3_k127_729334_3	311424.DhcVS_491	7.027e-102	348.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,34D2Y@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH3_k127_729334_6	706587.Desti_2062	1.021e-48	183.0	COG0662@1|root,COG1426@1|root,COG0662@2|Bacteria,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_25,HTH_3,HTH_31
WLSH3_k127_729334_1	1125863.JAFN01000001_gene170	2.666e-175	557.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_729334_0	1121430.JMLG01000004_gene880	1.404e-312	968.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24DPN@186801|Clostridia	186801|Clostridia	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WLSH3_k127_729334_8	387631.Asulf_01432	1.909e-06	56.0	COG1545@1|root,arCOG01283@2157|Archaea,2XX0U@28890|Euryarchaeota,24665@183980|Archaeoglobi	183980|Archaeoglobi	S	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
WLSH3_k127_729334_2	644282.Deba_1534	5.326e-138	451.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH3_k127_7353714_1	243164.DET0005	4.797e-104	347.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi,34CRS@301297|Dehalococcoidia	301297|Dehalococcoidia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WLSH3_k127_7353714_8	1128421.JAGA01000003_gene3357	6.164e-11	65.0	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WLSH3_k127_7353714_4	370438.PTH_0920	9.62e-50	183.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
WLSH3_k127_7353714_0	255470.cbdbA11	2.845e-119	390.0	COG0115@1|root,COG0115@2|Bacteria,2G5PM@200795|Chloroflexi,34CQR@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WLSH3_k127_7353714_3	457396.CSBG_02331	2.789e-53	196.0	COG0084@1|root,COG0084@2|Bacteria,1V29B@1239|Firmicutes,247TV@186801|Clostridia,36E0Q@31979|Clostridiaceae	186801|Clostridia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WLSH3_k127_7353714_6	994573.T472_0206040	6.467e-43	169.0	2DTR7@1|root,33MCI@2|Bacteria,1W5BS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7353714_2	1121405.dsmv_0211	3.247e-66	233.0	COG1024@1|root,COG1024@2|Bacteria,1RIVB@1224|Proteobacteria,42ZKD@68525|delta/epsilon subdivisions,2WUVX@28221|Deltaproteobacteria,2MNDG@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH3_k127_7353714_7	1123242.JH636434_gene3778	2.683e-11	67.0	COG0295@1|root,COG0295@2|Bacteria	2|Bacteria	F	cytidine deaminase activity	cdd_2	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
WLSH3_k127_7353714_5	1343739.PAP_00210	1.473e-48	177.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XWRG@28890|Euryarchaeota,244Y6@183968|Thermococci	183968|Thermococci	Q	O-methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
WLSH3_k127_7368705_3	525904.Tter_1692	2.116e-13	70.0	COG2178@1|root,COG2178@2|Bacteria,2NR1U@2323|unclassified Bacteria	2|Bacteria	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
WLSH3_k127_7368705_1	316274.Haur_1203	5.067e-85	290.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WLSH3_k127_7368705_0	439235.Dalk_2665	3.179e-100	338.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,42S7G@68525|delta/epsilon subdivisions,2WNH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_7368705_2	247633.GP2143_17291	2.44e-24	107.0	COG1960@1|root,COG1960@2|Bacteria,1R6EH@1224|Proteobacteria,1RMXW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_7472130_1	1144275.COCOR_04993	4.112e-104	343.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2YXED@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WLSH3_k127_7472130_2	886293.Sinac_3180	7.303e-58	209.0	COG0671@1|root,COG0671@2|Bacteria,2J3BG@203682|Planctomycetes	203682|Planctomycetes	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7472130_0	635013.TherJR_0871	2.285e-212	671.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2613E@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WLSH3_k127_7472130_3	552811.Dehly_0981	2.921e-42	163.0	COG0344@1|root,COG0344@2|Bacteria,2GARY@200795|Chloroflexi,34D74@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH3_k127_7472130_4	1121468.AUBR01000017_gene2370	3.454e-22	98.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,42GW8@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WLSH3_k127_7472130_5	292459.STH3140	0.0001242	44.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia	186801|Clostridia	J	elongation factor g	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH3_k127_7481092_2	1341646.CBMO010000010_gene783	1.835e-53	198.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,232FS@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WLSH3_k127_7481092_0	1121405.dsmv_0436	9.218e-91	313.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,42PK2@68525|delta/epsilon subdivisions,2WJS7@28221|Deltaproteobacteria,2MIWA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH3_k127_7481092_1	311424.DhcVS_1168	8.473e-58	204.0	COG1970@1|root,COG1970@2|Bacteria,2G9WW@200795|Chloroflexi,34DMM@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Large-conductance mechanosensitive channel, MscL	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WLSH3_k127_7481092_3	1089553.Tph_c26380	7.507e-14	72.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JKC@186801|Clostridia,42GW5@68295|Thermoanaerobacterales	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	3.1.3.3	ko:K22305	ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130	-	R00582	RC00017	ko00000,ko00001,ko01000	-	-	-	His_Phos_1
WLSH3_k127_7482475_1	1121468.AUBR01000007_gene253	1.443e-60	216.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,42G1K@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WLSH3_k127_7482475_3	555079.Toce_2117	3.586e-52	189.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,42FTZ@68295|Thermoanaerobacterales	186801|Clostridia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
WLSH3_k127_7482475_2	552811.Dehly_1711	1.676e-57	209.0	COG1211@1|root,COG1211@2|Bacteria,2G6UP@200795|Chloroflexi,34D6D@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
WLSH3_k127_7482475_0	311424.DhcVS_58	1.557e-136	445.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi,34CSA@301297|Dehalococcoidia	301297|Dehalococcoidia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase,ChlI
WLSH3_k127_7488389_10	932678.THERU_00330	1.568e-14	75.0	COG0492@1|root,COG0492@2|Bacteria,2G4H4@200783|Aquificae	200783|Aquificae	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH3_k127_7488389_2	311424.DhcVS_486	2.238e-126	415.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi,34D40@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WLSH3_k127_7488389_7	552811.Dehly_0300	4.053e-25	110.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi,34DAR@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
WLSH3_k127_7488389_9	1379698.RBG1_1C00001G1829	4.111e-16	79.0	COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L32p protein family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WLSH3_k127_7488389_3	243164.DET1276	4.814e-86	295.0	COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,34D34@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WLSH3_k127_7488389_6	1382356.JQMP01000003_gene1311	5.19e-35	138.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi,27YFI@189775|Thermomicrobia	189775|Thermomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WLSH3_k127_7488389_4	1163730.FFONT_1325	8.246e-81	287.0	COG1055@1|root,arCOG00238@2157|Archaea,2XQCU@28889|Crenarchaeota	28889|Crenarchaeota	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
WLSH3_k127_7488389_5	330214.NIDE3284	1.099e-58	219.0	COG3829@1|root,COG4191@1|root,COG5000@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,3J117@40117|Nitrospirae	40117|Nitrospirae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,PAS_4
WLSH3_k127_7488389_8	338963.Pcar_1994	7.426e-20	97.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43RYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH3_k127_7488389_1	316067.Geob_0214	4.591e-138	449.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cysteine-rich domain	bamD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_8
WLSH3_k127_7488389_0	880073.Calab_3046	2.018e-231	735.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
WLSH3_k127_7604649_2	485913.Krac_10794	2.331e-38	145.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WLSH3_k127_7604649_1	255470.cbdbB26	4.551e-40	150.0	COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,34DCQ@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
WLSH3_k127_7604649_3	1121405.dsmv_3288	5.669e-28	117.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH3_k127_7604649_0	552811.Dehly_1332	1.755e-76	263.0	arCOG03165@1|root,30AIC@2|Bacteria,2GANV@200795|Chloroflexi,34CWP@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7734943_3	439235.Dalk_3101	4.841e-41	170.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,42UB1@68525|delta/epsilon subdivisions,2WQ1B@28221|Deltaproteobacteria,2MNNK@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH3_k127_7734943_1	386456.JQKN01000002_gene2868	2.959e-103	341.0	COG1635@1|root,arCOG00574@2157|Archaea,2XTXH@28890|Euryarchaeota,23PFD@183925|Methanobacteria	183925|Methanobacteria	H	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur	thi4	-	-	ko:K03146	ko00730,ko01100,map00730,map01100	-	R10685	RC00033,RC03253,RC03254	ko00000,ko00001	-	-	-	Thi4
WLSH3_k127_7734943_0	255470.cbdbA872	2.203e-192	606.0	COG1900@1|root,COG1900@2|Bacteria,2GASV@200795|Chloroflexi,34DA0@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Homocysteine biosynthesis enzyme, sulfur-incorporation	-	-	-	-	-	-	-	-	-	-	-	-	HcyBio
WLSH3_k127_7734943_2	311424.DhcVS_791	3.335e-51	184.0	COG1148@1|root,COG1148@2|Bacteria,2GATY@200795|Chloroflexi,34DC8@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NIL	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIL
WLSH3_k127_7734943_4	1121405.dsmv_3459	3.059e-31	127.0	COG2122@1|root,COG2122@2|Bacteria,1MV9Z@1224|Proteobacteria,42PMZ@68525|delta/epsilon subdivisions,2WMF7@28221|Deltaproteobacteria,2MJ13@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM ApbE family	-	-	-	ko:K09740	-	-	-	-	ko00000	-	-	-	-
WLSH3_k127_7744778_1	1382306.JNIM01000001_gene979	1.375e-54	195.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi	200795|Chloroflexi	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WLSH3_k127_7744778_0	645991.Sgly_0152	8.921e-114	378.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia,2633J@186807|Peptococcaceae	186801|Clostridia	Q	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WLSH3_k127_7790568_0	311424.DhcVS_481	8.606e-149	482.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi,34D09@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WLSH3_k127_7790568_2	311424.DhcVS_480	2.823e-36	145.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi,34CRZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
WLSH3_k127_7790568_1	255470.cbdbA512	7.62e-146	476.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi,34CQC@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Bacterial dnaA  protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
WLSH3_k127_7790568_3	552811.Dehly_1377	8.885e-28	126.0	COG4818@1|root,COG4818@2|Bacteria,2G9D6@200795|Chloroflexi,34DD3@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
WLSH3_k127_7790568_4	1123371.ATXH01000002_gene392	3.646e-18	86.0	COG0655@1|root,COG0655@2|Bacteria,2GHUQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WLSH3_k127_7973376_9	552811.Dehly_1034	1.763e-27	115.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi,34DE1@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
WLSH3_k127_7973376_7	765420.OSCT_0630	4.608e-38	147.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi,375RY@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
WLSH3_k127_7973376_3	1382356.JQMP01000004_gene434	2.414e-137	445.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi,27XKF@189775|Thermomicrobia	189775|Thermomicrobia	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WLSH3_k127_7973376_5	552811.Dehly_0741	6.478e-80	277.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,34D5G@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WLSH3_k127_7973376_1	255470.cbdbA583	1.512e-140	458.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi,34D17@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WLSH3_k127_7973376_2	255470.cbdbA581	2.993e-139	451.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi,34CWR@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WLSH3_k127_7973376_0	243164.DET0599	1.331e-189	605.0	COG0111@1|root,COG0111@2|Bacteria,2G67B@200795|Chloroflexi,34CNE@301297|Dehalococcoidia	301297|Dehalococcoidia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WLSH3_k127_7973376_4	243164.DET0597	1.389e-99	339.0	COG4198@1|root,COG4198@2|Bacteria,2G6FC@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
WLSH3_k127_7973376_8	552811.Dehly_0119	8.971e-38	147.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi,34DBW@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
WLSH3_k127_7973376_10	485913.Krac_7647	2.122e-09	60.0	COG0828@1|root,COG0828@2|Bacteria,2G7EY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WLSH3_k127_7973376_6	1131269.AQVV01000003_gene707	1.607e-70	243.0	COG0332@1|root,COG0332@2|Bacteria	2|Bacteria	I	beta-ketoacyl-acyl-carrier-protein synthase III activity	fabH1	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C,Thiolase_N
WLSH3_k127_8041861_2	1089546.AQUI01000002_gene3578	2.114e-16	79.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,409ZR@622450|Actinopolysporales	201174|Actinobacteria	H	SNO glutamine amidotransferase family	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
WLSH3_k127_8041861_0	311424.DhcVS_834	6.029e-121	398.0	COG1693@1|root,COG1693@2|Bacteria,2GAMC@200795|Chloroflexi,34CRM@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Ribonuclease R winged-helix domain	-	-	-	ko:K09720	-	-	-	-	ko00000,ko03000	-	-	-	DUF128,HTH_12
WLSH3_k127_8041861_1	255470.cbdbA916	2.344e-76	261.0	COG0107@1|root,COG0107@2|Bacteria,2G5Y2@200795|Chloroflexi,34CXS@301297|Dehalococcoidia	301297|Dehalococcoidia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	-	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WLSH3_k127_8050526_1	1499967.BAYZ01000184_gene4603	7.176e-101	334.0	COG0778@1|root,COG0778@2|Bacteria,2NPIF@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_8050526_0	1183438.GKIL_2511	2.512e-119	400.0	COG2986@1|root,COG2986@2|Bacteria,1G3FJ@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Phenylalanine and histidine ammonia-lyase	hutH	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009072,GO:0009698,GO:0009699,GO:0009800,GO:0009803,GO:0009987,GO:0016043,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019748,GO:0019752,GO:0022607,GO:0032787,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044550,GO:0045548,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	4.3.1.24,4.3.1.3	ko:K01745,ko:K10775	ko00340,ko00360,ko00940,ko01100,ko01110,map00340,map00360,map00940,map01100,map01110	M00039,M00045,M00137,M00350	R00697,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WLSH3_k127_8050526_2	768710.DesyoDRAFT_4784	3.88e-40	153.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,260GS@186807|Peptococcaceae	186801|Clostridia	E	PFAM Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K01746	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
WLSH3_k127_8084491_4	1158345.JNLL01000001_gene1630	1.017e-05	47.0	COG1254@1|root,COG1254@2|Bacteria,2G49Q@200783|Aquificae	200783|Aquificae	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WLSH3_k127_8084491_3	330779.Saci_1420	1.373e-06	50.0	COG1254@1|root,arCOG01674@2157|Archaea,2XR8S@28889|Crenarchaeota	28889|Crenarchaeota	C	PFAM acylphosphatase	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WLSH3_k127_8084491_1	255470.cbdbA999	8.88e-79	270.0	COG2006@1|root,COG2006@2|Bacteria,2GBW5@200795|Chloroflexi,34D28@301297|Dehalococcoidia	301297|Dehalococcoidia	S	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
WLSH3_k127_8084491_2	909663.KI867151_gene3156	2.164e-64	227.0	COG2220@1|root,COG2220@2|Bacteria,1QB9E@1224|Proteobacteria,42N7W@68525|delta/epsilon subdivisions,2WNMC@28221|Deltaproteobacteria,2MQPI@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
WLSH3_k127_8084491_0	401526.TcarDRAFT_0013	3.353e-152	496.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,4H3I7@909932|Negativicutes	909932|Negativicutes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WLSH3_k127_8109626_2	906888.JCM19314_363	1.811e-13	72.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1HWZ6@117743|Flavobacteriia,3HJCZ@363408|Nonlabens	976|Bacteroidetes	K	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_8109626_1	1242864.D187_005157	3.179e-38	158.0	COG0642@1|root,COG2205@2|Bacteria	1242864.D187_005157|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8109626_0	429009.Adeg_2013	1.93e-61	216.0	COG3259@1|root,COG3259@2|Bacteria,1UZNV@1239|Firmicutes,24F0H@186801|Clostridia,42HYI@68295|Thermoanaerobacterales	186801|Clostridia	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WLSH3_k127_8174363_2	552811.Dehly_1197	5.329e-117	385.0	COG4826@1|root,COG4826@2|Bacteria,2GBWN@200795|Chloroflexi,34D50@301297|Dehalococcoidia	301297|Dehalococcoidia	M	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
WLSH3_k127_8174363_1	351160.RCIX2726	2.293e-134	450.0	COG1948@1|root,arCOG02284@2157|Archaea,2XT7B@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Beta propeller domain	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Beta_propel,Inhibitor_I42
WLSH3_k127_8174363_0	351160.RCIX2726	1.693e-140	471.0	COG1948@1|root,arCOG02284@2157|Archaea,2XT7B@28890|Euryarchaeota	28890|Euryarchaeota	L	PFAM Beta propeller domain	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	Beta_propel,Inhibitor_I42
WLSH3_k127_8174363_4	243164.DET0169	1.205e-35	142.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WLSH3_k127_8174363_3	448385.sce5265	1.99e-41	160.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42PY0@68525|delta/epsilon subdivisions,2WJ2Y@28221|Deltaproteobacteria,2YW6C@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH3_k127_8343339_9	1121468.AUBR01000046_gene1908	1.212e-43	170.0	COG1082@1|root,COG1082@2|Bacteria,1V1Y1@1239|Firmicutes,24Y9G@186801|Clostridia,42HWD@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
WLSH3_k127_8343339_8	255470.cbdbA940	9.991e-44	166.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi,34D5W@301297|Dehalococcoidia	301297|Dehalococcoidia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WLSH3_k127_8343339_2	552811.Dehly_0529	2.032e-170	544.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi,34D3D@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WLSH3_k127_8343339_6	255470.cbdbA935	1.335e-120	394.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi,34CY7@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WLSH3_k127_8343339_4	552811.Dehly_0532	1.564e-134	437.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi,34CM5@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WLSH3_k127_8343339_7	243164.DET0971	3.253e-78	270.0	COG0289@1|root,COG0289@2|Bacteria,2G7CZ@200795|Chloroflexi,34D6H@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
WLSH3_k127_8343339_0	552811.Dehly_0534	4.342e-247	782.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi,34CYC@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WLSH3_k127_8343339_10	309801.trd_0624	2.021e-20	93.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi,27YK2@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal_S15	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WLSH3_k127_8343339_1	311424.DhcVS_1196	4.033e-203	641.0	COG0034@1|root,COG0034@2|Bacteria,2G61T@200795|Chloroflexi,34CJ3@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
WLSH3_k127_8343339_5	243164.DET1416	1.197e-121	399.0	COG0150@1|root,COG0150@2|Bacteria,2G5YZ@200795|Chloroflexi,34D95@301297|Dehalococcoidia	301297|Dehalococcoidia	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WLSH3_k127_8343339_3	255470.cbdbA1381	9.9e-143	462.0	COG0138@1|root,COG0138@2|Bacteria,2G5JG@200795|Chloroflexi,34CRG@301297|Dehalococcoidia	301297|Dehalococcoidia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WLSH3_k127_8354516_0	439235.Dalk_5191	1.279e-82	292.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42NTV@68525|delta/epsilon subdivisions,2WJTP@28221|Deltaproteobacteria,2MIWR@213118|Desulfobacterales	1224|Proteobacteria	C	PFAM CoA-binding domain protein	MA20_15065	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WLSH3_k127_8354516_1	326427.Cagg_0764	3.658e-50	186.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi,375M0@32061|Chloroflexia	32061|Chloroflexia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WLSH3_k127_8367511_10	1128421.JAGA01000003_gene2724	0.0001411	45.0	COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WLSH3_k127_8367511_3	1128421.JAGA01000002_gene123	3.627e-116	390.0	COG0297@1|root,COG0297@2|Bacteria,2NP1F@2323|unclassified Bacteria	2|Bacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	iLJ478.TM0895	Glyco_transf_5,Glycos_transf_1
WLSH3_k127_8367511_0	479434.Sthe_1091	4.538e-269	835.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi,27XZS@189775|Thermomicrobia	189775|Thermomicrobia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
WLSH3_k127_8367511_8	1173027.Mic7113_3739	3.683e-56	198.0	COG0296@1|root,COG0296@2|Bacteria,1GD05@1117|Cyanobacteria,1HEAH@1150|Oscillatoriales	1117|Cyanobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
WLSH3_k127_8367511_4	552811.Dehly_1218	7.581e-105	350.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi,34CKX@301297|Dehalococcoidia	301297|Dehalococcoidia	G	DeoC/LacD family aldolase	-	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
WLSH3_k127_8367511_6	373903.Hore_16050	5.496e-81	280.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WB29@53433|Halanaerobiales	186801|Clostridia	GK	TIGRFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
WLSH3_k127_8367511_1	357808.RoseRS_1575	2.277e-201	638.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
WLSH3_k127_8367511_2	311424.DhcVS_1009	3.222e-154	496.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,34CUN@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WLSH3_k127_8367511_5	485913.Krac_0779	1.465e-90	314.0	COG0642@1|root,COG2205@2|Bacteria,2GBIC@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WLSH3_k127_8367511_7	485913.Krac_11359	5.236e-77	264.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_8367511_9	243164.DET0715	2.78e-24	108.0	COG0006@1|root,COG0006@2|Bacteria,2G6AE@200795|Chloroflexi,34CW7@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
WLSH3_k127_8372076_5	552811.Dehly_0299	8.089e-24	104.0	COG0014@1|root,COG0014@2|Bacteria,2G5TY@200795|Chloroflexi,34CYU@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WLSH3_k127_8372076_0	243164.DET1282	1.32e-132	433.0	COG0263@1|root,COG0263@2|Bacteria,2G67X@200795|Chloroflexi,34CYZ@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WLSH3_k127_8372076_4	574087.Acear_1368	1.721e-39	151.0	COG1671@1|root,COG1671@2|Bacteria,1VC3V@1239|Firmicutes,24N3K@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8372076_3	304371.MCP_0732	1.859e-50	183.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WLSH3_k127_8372076_2	243164.DET1203	5.575e-63	227.0	COG0543@1|root,COG0543@2|Bacteria,2G75X@200795|Chloroflexi,34D0J@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
WLSH3_k127_8372076_1	552811.Dehly_0915	9.044e-87	291.0	COG0458@1|root,COG0458@2|Bacteria,2G5NX@200795|Chloroflexi,34D66@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
WLSH3_k127_8389720_0	671143.DAMO_2616	2.642e-174	558.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_8449965_1	867845.KI911784_gene3155	6.321e-52	187.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi,375B7@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WLSH3_k127_8449965_0	795359.TOPB45_0362	9.602e-70	251.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	1.3.1.101,1.3.7.11,5.5.1.18	ko:K06444,ko:K17830	ko00564,ko00906,ko01100,ko01110,map00564,map00906,map01100,map01110	-	R06960,R06963,R07840,R10325,R10326,R10331	RC01612,RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2,Trp_halogenase
WLSH3_k127_8449965_2	1243664.CAVL020000058_gene4450	4.968e-05	51.0	COG1846@1|root,COG1846@2|Bacteria,1V7N0@1239|Firmicutes,4HK1S@91061|Bacilli,1ZJ3V@1386|Bacillus	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WLSH3_k127_8569000_0	243164.DET1425	9.382e-123	407.0	COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi,34CK7@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WLSH3_k127_8569000_1	1122147.AUEH01000021_gene613	8.758e-06	48.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,3F5SD@33958|Lactobacillaceae	91061|Bacilli	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WLSH3_k127_8603079_0	247490.KSU1_D0589	2.504e-144	466.0	COG0380@1|root,COG0380@2|Bacteria,2IYNH@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyltransferase family 20	-	-	2.4.1.15,3.1.3.12	ko:K16055	ko00500,ko01100,map00500,map01100	-	R02737,R02778	RC00005,RC00017,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
WLSH3_k127_8603079_1	335543.Sfum_3485	7.398e-119	396.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2MQBW@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
WLSH3_k127_8603079_2	311424.DhcVS_1456	2.277e-91	317.0	COG0668@1|root,COG0668@2|Bacteria,2G75W@200795|Chloroflexi,34D81@301297|Dehalococcoidia	301297|Dehalococcoidia	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
WLSH3_k127_8603079_3	56780.SYN_02093	1.153e-08	59.0	COG1102@1|root,COG1102@2|Bacteria,1RCTZ@1224|Proteobacteria,42R0B@68525|delta/epsilon subdivisions,2WMVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
WLSH3_k127_8606218_0	552811.Dehly_0937	3.028e-242	767.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,34D01@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WLSH3_k127_8606218_2	552811.Dehly_0935	3.572e-153	501.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi,34CPP@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
WLSH3_k127_8606218_5	255470.cbdbA1186	9.593e-15	76.0	COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi,34DI9@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WLSH3_k127_8606218_4	1343739.PAP_01065	1.089e-40	154.0	COG0454@1|root,arCOG00826@2157|Archaea,2Y240@28890|Euryarchaeota	28890|Euryarchaeota	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH3_k127_8606218_3	477974.Daud_1586	1.133e-80	275.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,260WX@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WLSH3_k127_8606218_1	311424.DhcVS_1044	2.742e-170	546.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi,34D3N@301297|Dehalococcoidia	301297|Dehalococcoidia	E	arginine biosynthetic process via ornithine	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
WLSH3_k127_8666344_1	311424.DhcVS_1190	1.488e-34	134.0	COG0176@1|root,COG0176@2|Bacteria,2G6T8@200795|Chloroflexi,34D7M@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
WLSH3_k127_8666344_0	552811.Dehly_1436	3.563e-213	671.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi,34CRC@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WLSH3_k127_8685543_3	1235799.C818_01899	1.984e-06	53.0	COG4887@1|root,COG4887@2|Bacteria,1V4ZU@1239|Firmicutes,24CCD@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1847
WLSH3_k127_8685543_2	552811.Dehly_1121	5.501e-18	85.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,34CPV@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WLSH3_k127_8685543_1	1238182.C882_0236	3.657e-40	163.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2JQ0U@204441|Rhodospirillales	204441|Rhodospirillales	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
WLSH3_k127_8685543_0	768706.Desor_0870	5.861e-85	288.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,260VS@186807|Peptococcaceae	186801|Clostridia	IQ	PFAM short chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
WLSH3_k127_8696153_2	1089553.Tph_c09420	3.595e-10	63.0	COG1415@1|root,COG1415@2|Bacteria,1UWH7@1239|Firmicutes,24DPJ@186801|Clostridia,42EWV@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
WLSH3_k127_8696153_0	688269.Theth_0193	8.107e-92	307.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_8696153_1	416591.Tlet_1834	2.181e-74	259.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH3_k127_8713759_2	224325.AF_2243	6.317e-100	335.0	COG0183@1|root,arCOG01282@2157|Archaea,2XT8C@28890|Euryarchaeota	28890|Euryarchaeota	I	Acetyl-CoA acetyltransferase	aca1	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WLSH3_k127_8713759_0	439235.Dalk_3104	1.686e-218	692.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MIAR@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH3_k127_8713759_1	555088.DealDRAFT_0572	3.262e-115	376.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,42KAM@68298|Syntrophomonadaceae	186801|Clostridia	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WLSH3_k127_8713759_3	986075.CathTA2_1528	2.485e-88	298.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli	91061|Bacilli	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WLSH3_k127_8713759_4	439235.Dalk_3103	8.884e-10	59.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria,2MJX3@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WLSH3_k127_8719406_1	247490.KSU1_D0177	1.157e-161	519.0	COG0513@1|root,COG0513@2|Bacteria,2IX18@203682|Planctomycetes	203682|Planctomycetes	L	COG0513 Superfamily II DNA and RNA	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WLSH3_k127_8719406_7	243164.DET1448	2.104e-14	74.0	29WVC@1|root,30IH0@2|Bacteria,2G9KW@200795|Chloroflexi,34DPM@301297|Dehalococcoidia	301297|Dehalococcoidia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8719406_3	748449.Halha_1194	6.692e-56	211.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,3WC46@53433|Halanaerobiales	186801|Clostridia	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
WLSH3_k127_8719406_2	211165.AJLN01000037_gene1985	1.585e-58	210.0	COG2518@1|root,COG2518@2|Bacteria,1G8RI@1117|Cyanobacteria	1117|Cyanobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8719406_6	315749.Bcer98_1888	1.47e-14	80.0	2EFWI@1|root,339NT@2|Bacteria,1V760@1239|Firmicutes,4HRWM@91061|Bacilli,1ZJVU@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8719406_5	909663.KI867150_gene1074	4.651e-36	140.0	COG1917@1|root,COG1917@2|Bacteria,1N2JS@1224|Proteobacteria,42TR3@68525|delta/epsilon subdivisions,2WQ4M@28221|Deltaproteobacteria,2MSCX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH3_k127_8719406_0	158190.SpiGrapes_3087	1.421e-170	545.0	COG0493@1|root,COG1233@1|root,COG0493@2|Bacteria,COG1233@2|Bacteria,2J838@203691|Spirochaetes	203691|Spirochaetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.23,5.2.1.13	ko:K09516,ko:K09835	ko00830,ko00906,ko01100,ko01110,map00830,map00906,map01100,map01110	M00097	R07163,R07512	RC01835,RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
WLSH3_k127_8745920_0	272844.PAB1970	2.627e-107	355.0	COG1350@1|root,arCOG01432@2157|Archaea,2Y845@28890|Euryarchaeota,2438I@183968|Thermococci	183968|Thermococci	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH3_k127_8745920_1	264732.Moth_2019	2.177e-44	165.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,42H4U@68295|Thermoanaerobacterales	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WLSH3_k127_8745920_2	370438.PTH_0854	7.824e-20	95.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,262CC@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
WLSH3_k127_880310_0	335543.Sfum_1223	1.496e-119	389.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2MQFX@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WLSH3_k127_880310_2	264732.Moth_1331	7.84e-53	196.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,42GBW@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WLSH3_k127_880310_3	1452536.JARE01000012_gene1695	1.493e-34	141.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4FM3W@85023|Microbacteriaceae	201174|Actinobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH3_k127_880310_1	255470.cbdbA1294	2.127e-73	257.0	COG0761@1|root,COG0761@2|Bacteria,2G75Z@200795|Chloroflexi,34CJU@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
WLSH3_k127_8905320_0	552811.Dehly_1505	8.044e-59	216.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi,34D0N@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WLSH3_k127_8905320_1	867845.KI911784_gene2183	1.373e-34	135.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,376AC@32061|Chloroflexia	32061|Chloroflexia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WLSH3_k127_8918122_0	552811.Dehly_1025	4.196e-142	457.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi,34CX6@301297|Dehalococcoidia	301297|Dehalococcoidia	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WLSH3_k127_8918122_1	1288963.ADIS_1306	5.565e-49	190.0	COG2271@1|root,COG2271@2|Bacteria,4PM8E@976|Bacteroidetes,47YKN@768503|Cytophagia	976|Bacteroidetes	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_8918122_2	1247024.JRLH01000001_gene723	0.0005303	44.0	2DSWF@1|root,33HPF@2|Bacteria,1NMM8@1224|Proteobacteria,1SIHM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8980476_3	255470.cbdbA3	9.402e-50	183.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,34D3W@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH3_k127_8980476_1	926550.CLDAP_12040	5.343e-89	304.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
WLSH3_k127_8980476_0	243164.DET0001	1.917e-100	343.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi,34CS8@301297|Dehalococcoidia	301297|Dehalococcoidia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WLSH3_k127_8980476_2	1124983.PFLCHA0_c00220	1.713e-70	246.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,1YMV9@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Formyl_trans_C,Formyl_trans_N
WLSH3_k127_9000210_1	869210.Marky_0082	1.236e-86	291.0	COG1215@1|root,COG1215@2|Bacteria,1WM49@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth)	-	-	2.4.1.217	ko:K05947	ko00051,map00051	-	R05768	RC00005,RC00397,RC02748	ko00000,ko00001,ko01000,ko01003	-	-	-	Osmo_MPGsynth
WLSH3_k127_9000210_2	1094980.Mpsy_2703	1.898e-71	250.0	COG3769@1|root,arCOG01215@2157|Archaea,2XZBT@28890|Euryarchaeota	28890|Euryarchaeota	S	Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG)	mngB	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
WLSH3_k127_9000210_0	1128421.JAGA01000004_gene2681	2.575e-110	367.0	COG0012@1|root,COG0012@2|Bacteria,2NNNF@2323|unclassified Bacteria	2|Bacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WLSH3_k127_9000210_3	552811.Dehly_1505	6.859e-67	240.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi,34D0N@301297|Dehalococcoidia	301297|Dehalococcoidia	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WLSH3_k127_9000210_4	555088.DealDRAFT_1203	2.303e-48	177.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
WLSH3_k127_9000210_6	1123371.ATXH01000011_gene56	1.178e-05	57.0	COG1533@1|root,COG1533@2|Bacteria,2GHCA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WLSH3_k127_9000210_5	1121472.AQWN01000001_gene188	2.944e-21	94.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WLSH3_k127_9018823_2	4558.Sb01g031890.1	0.0004646	47.0	KOG1721@1|root,KOG1721@2759|Eukaryota,37TRK@33090|Viridiplantae,3GGRF@35493|Streptophyta,3M4DS@4447|Liliopsida,3IKHK@38820|Poales	35493|Streptophyta	S	C2H2-type zinc finger	-	GO:0001101,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0009414,GO:0009415,GO:0009628,GO:0010035,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0050896,GO:1901700	-	-	-	-	-	-	-	-	-	-	zf-C2H2_6
WLSH3_k127_9018823_1	926550.CLDAP_25550	5.889e-46	182.0	COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,2G8PE@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WLSH3_k127_9018823_0	871963.Desdi_0961	7.001e-61	218.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24IAA@186801|Clostridia,26539@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WLSH3_k127_9028199_1	387631.Asulf_02259	1.716e-53	192.0	COG0105@1|root,arCOG04313@2157|Archaea,2XWSK@28890|Euryarchaeota,2465T@183980|Archaeoglobi	183980|Archaeoglobi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WLSH3_k127_9028199_2	311424.DhcVS_338	9.816e-51	194.0	COG0637@1|root,COG1214@1|root,COG0637@2|Bacteria,COG1214@2|Bacteria,2G6ZZ@200795|Chloroflexi,34D2B@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Glycoprotease family	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Peptidase_M22
WLSH3_k127_9028199_5	401526.TcarDRAFT_0671	8.506e-23	111.0	COG2050@1|root,COG2050@2|Bacteria,1V824@1239|Firmicutes,4H4QB@909932|Negativicutes	909932|Negativicutes	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WLSH3_k127_9028199_4	765420.OSCT_2935	2.222e-37	150.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi,375PU@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
WLSH3_k127_9028199_3	255470.cbdbA346	1.301e-44	168.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,34CZN@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WLSH3_k127_9028199_0	243164.DET0397	2.578e-74	263.0	COG0611@1|root,COG0611@2|Bacteria,2G6SH@200795|Chloroflexi,34CMT@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WLSH3_k127_9028199_6	498761.HM1_1697	3.4e-16	81.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WLSH3_k127_905754_1	1291050.JAGE01000001_gene2868	1.27e-92	317.0	COG0826@1|root,COG0826@2|Bacteria,1VT61@1239|Firmicutes,24AZY@186801|Clostridia,3WRXE@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
WLSH3_k127_905754_0	634956.Geoth_3060	2.233e-111	374.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1WE7S@129337|Geobacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
WLSH3_k127_905754_4	1120973.AQXL01000129_gene2446	3.737e-21	94.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,27AT7@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH3_k127_905754_2	562970.Btus_2604	8.574e-59	209.0	COG1028@1|root,COG1028@2|Bacteria,1TRVE@1239|Firmicutes,4HCFY@91061|Bacilli,27AT7@186823|Alicyclobacillaceae	91061|Bacilli	IQ	KR domain	fabL	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH3_k127_905754_5	224324.aq_1717a	4.013e-13	72.0	COG0236@1|root,COG0236@2|Bacteria,2G491@200783|Aquificae	200783|Aquificae	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH3_k127_905754_3	1031288.AXAA01000001_gene2264	4.035e-54	199.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,36E96@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WLSH3_k127_9077038_19	552811.Dehly_1081	1.054e-07	55.0	COG0256@1|root,COG0256@2|Bacteria,2G6Y4@200795|Chloroflexi,34DAD@301297|Dehalococcoidia	301297|Dehalococcoidia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
WLSH3_k127_9077038_5	986075.CathTA2_2518	6.158e-67	232.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
WLSH3_k127_9077038_10	485913.Krac_12514	2.094e-46	170.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
WLSH3_k127_9077038_16	552811.Dehly_1084	6.286e-24	102.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi,34DIY@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
WLSH3_k127_9077038_3	1089553.Tph_c25730	7.314e-74	252.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,42F2S@68295|Thermoanaerobacterales	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
WLSH3_k127_9077038_13	243164.DET0485	6.608e-38	144.0	COG0198@1|root,COG0198@2|Bacteria,2G750@200795|Chloroflexi,34DCX@301297|Dehalococcoidia	301297|Dehalococcoidia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
WLSH3_k127_9077038_9	485913.Krac_12518	1.974e-48	175.0	COG0093@1|root,COG0093@2|Bacteria,2G6MZ@200795|Chloroflexi	200795|Chloroflexi	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
WLSH3_k127_9077038_15	292459.STH3066	4.045e-27	114.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
WLSH3_k127_9077038_18	311424.DhcVS_425	1.93e-13	72.0	COG0255@1|root,COG0255@2|Bacteria,2G7DB@200795|Chloroflexi,34DH7@301297|Dehalococcoidia	301297|Dehalococcoidia	J	structural constituent of ribosome	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
WLSH3_k127_9077038_4	1069080.KB913028_gene476	3.521e-72	250.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4H3BP@909932|Negativicutes	909932|Negativicutes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WLSH3_k127_9077038_14	311424.DhcVS_422	2.349e-36	140.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi,34DE4@301297|Dehalococcoidia	301297|Dehalococcoidia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
WLSH3_k127_9077038_12	643648.Slip_2233	5.938e-38	144.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,42K2B@68298|Syntrophomonadaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
WLSH3_k127_9077038_1	309801.trd_0981	9.06e-118	386.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi,27XVH@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WLSH3_k127_9077038_17	552811.Dehly_1095	1.457e-22	100.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi,34DEW@301297|Dehalococcoidia	301297|Dehalococcoidia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
WLSH3_k127_9077038_7	311424.DhcVS_418	1.223e-59	212.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi,34CM4@301297|Dehalococcoidia	301297|Dehalococcoidia	J	50S ribosomal protein L4	rplD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
WLSH3_k127_9077038_2	525904.Tter_0715	3.614e-75	258.0	COG0087@1|root,COG0087@2|Bacteria,2NPAI@2323|unclassified Bacteria	2|Bacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
WLSH3_k127_9077038_11	311424.DhcVS_416	3.035e-39	148.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi,34DED@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
WLSH3_k127_9077038_0	525904.Tter_0712	4.869e-271	850.0	COG0480@1|root,COG0480@2|Bacteria,2NNSV@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH3_k127_9077038_8	1382356.JQMP01000003_gene2257	2.908e-50	183.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi,27Y66@189775|Thermomicrobia	189775|Thermomicrobia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
WLSH3_k127_9077038_6	552811.Dehly_1101	3.133e-63	219.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi,34D33@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
WLSH3_k127_9152473_9	926569.ANT_31550	4.063e-13	70.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WLSH3_k127_9152473_4	439235.Dalk_3794	2.64e-52	194.0	COG1024@1|root,COG1024@2|Bacteria,1MW41@1224|Proteobacteria,42N51@68525|delta/epsilon subdivisions,2WKBV@28221|Deltaproteobacteria,2MIQE@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WLSH3_k127_9152473_1	552811.Dehly_1402	2.139e-117	391.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,34CMZ@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH3_k127_9152473_0	479434.Sthe_0845	1.293e-234	737.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,27Y1U@189775|Thermomicrobia	189775|Thermomicrobia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WLSH3_k127_9152473_6	429009.Adeg_0160	1.472e-36	140.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,42GV4@68295|Thermoanaerobacterales	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WLSH3_k127_9152473_8	864702.OsccyDRAFT_1898	1.15e-16	82.0	COG2944@1|root,COG2944@2|Bacteria,1G6V7@1117|Cyanobacteria,1HBR9@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WLSH3_k127_9152473_5	237368.SCABRO_01803	4.612e-45	181.0	28HQ3@1|root,2Z7XW@2|Bacteria,2J224@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
WLSH3_k127_9152473_2	279010.BL01501	5.022e-92	314.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,1ZB55@1386|Bacillus	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WLSH3_k127_9152473_7	679935.Alfi_3272	1.181e-20	95.0	COG1146@1|root,COG1146@2|Bacteria,4NV91@976|Bacteroidetes,2FTXT@200643|Bacteroidia,22VMY@171550|Rikenellaceae	976|Bacteroidetes	C	4Fe-4S binding domain	oorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_21,Fer4_4
WLSH3_k127_9152473_3	459349.CLOAM1002	1.396e-76	260.0	COG0674@1|root,COG0674@2|Bacteria,2NNWT@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH3_k127_9182904_5	420246.GTNG_0575	4.806e-65	238.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,1WEIW@129337|Geobacillus	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	lcfB_2	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH3_k127_9182904_0	926569.ANT_30000	2.252e-163	542.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
WLSH3_k127_9182904_10	1132441.KI519454_gene1595	6.503e-17	90.0	COG1503@1|root,COG1503@2|Bacteria,2IFQH@201174|Actinobacteria,1W9KR@1268|Micrococcaceae	201174|Actinobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9182904_8	304371.MCP_2781	1.679e-30	129.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y7TC@28890|Euryarchaeota,2NBMF@224756|Methanomicrobia	224756|Methanomicrobia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9182904_4	1499967.BAYZ01000137_gene110	1.72e-82	284.0	COG1600@1|root,COG1600@2|Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Fer4_16
WLSH3_k127_9182904_6	311424.DhcVS_362	3.183e-59	213.0	COG0834@1|root,COG0834@2|Bacteria,2G7BD@200795|Chloroflexi,34CRW@301297|Dehalococcoidia	301297|Dehalococcoidia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WLSH3_k127_9182904_1	552811.Dehly_0402	1.014e-127	413.0	COG0765@1|root,COG0765@2|Bacteria,2G6IJ@200795|Chloroflexi,34D73@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
WLSH3_k127_9182904_2	552811.Dehly_0403	2.015e-117	381.0	COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,34CW1@301297|Dehalococcoidia	301297|Dehalococcoidia	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
WLSH3_k127_9182904_3	868131.MSWAN_1064	2.299e-94	317.0	COG2006@1|root,arCOG02446@2157|Archaea,2XV9B@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
WLSH3_k127_9182904_9	247490.KSU1_D1055	1.004e-21	98.0	2C4PS@1|root,2ZHNK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9266975_7	1267534.KB906757_gene911	1.96e-33	142.0	COG3867@1|root,COG4257@1|root,COG3867@2|Bacteria,COG4257@2|Bacteria,3Y9AI@57723|Acidobacteria	57723|Acidobacteria	V	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
WLSH3_k127_9266975_8	318464.IO99_13100	2.484e-26	111.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,36M0F@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
WLSH3_k127_9266975_10	1206730.BAGA01000065_gene1468	3.601e-05	55.0	2CA5R@1|root,2Z81H@2|Bacteria,2GM6V@201174|Actinobacteria,4FVE9@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9266975_2	255470.cbdbA588	5.527e-145	467.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi,34D5N@301297|Dehalococcoidia	301297|Dehalococcoidia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WLSH3_k127_9266975_0	243164.DET0604	0.0	1592.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,34CZR@301297|Dehalococcoidia	301297|Dehalococcoidia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WLSH3_k127_9266975_1	309801.trd_0991	0.0	1339.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi,27XNX@189775|Thermomicrobia	189775|Thermomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WLSH3_k127_9266975_4	439235.Dalk_4172	4.72e-89	306.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2MI0N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_9266975_5	1033802.SSPSH_001731	2.806e-74	265.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPW2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_9266975_3	517722.AEUE01000001_gene2842	2.651e-96	323.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,2KCNC@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WLSH3_k127_9266975_6	1120973.AQXL01000133_gene1712	4.192e-69	243.0	COG1028@1|root,COG1028@2|Bacteria,1UYVZ@1239|Firmicutes	1239|Firmicutes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH3_k127_9266975_9	439235.Dalk_3908	4.91e-24	104.0	COG2030@1|root,COG2030@2|Bacteria,1Q5QU@1224|Proteobacteria,431N3@68525|delta/epsilon subdivisions,2WWWX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
WLSH3_k127_9268208_5	457570.Nther_0987	6.437e-07	54.0	COG0842@1|root,COG0842@2|Bacteria,1TSVV@1239|Firmicutes,24FCX@186801|Clostridia	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WLSH3_k127_9268208_1	192952.MM_1231	2.903e-50	185.0	arCOG02703@1|root,arCOG02703@2157|Archaea	2157|Archaea	S	Methyltransferase type 11	aknG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
WLSH3_k127_9268208_0	243164.DET0104	5.17e-110	365.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi,34D5X@301297|Dehalococcoidia	301297|Dehalococcoidia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	ParA
WLSH3_k127_9268208_4	1382356.JQMP01000004_gene600	4.053e-28	118.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,27Y6P@189775|Thermomicrobia	189775|Thermomicrobia	H	MoaE protein	-	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
WLSH3_k127_9268208_2	1121430.JMLG01000003_gene523	4.913e-44	164.0	COG0822@1|root,COG0822@2|Bacteria,1VCI2@1239|Firmicutes,24MWW@186801|Clostridia,265KS@186807|Peptococcaceae	186801|Clostridia	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WLSH3_k127_9268208_3	386456.JQKN01000013_gene3025	1.428e-28	118.0	COG0731@1|root,arCOG00953@2157|Archaea,2XUIN@28890|Euryarchaeota	28890|Euryarchaeota	J	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
WLSH3_k127_927584_0	243164.DET0430	6.839e-290	902.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,34D5F@301297|Dehalococcoidia	301297|Dehalococcoidia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WLSH3_k127_927584_1	552811.Dehly_0251	1.317e-127	419.0	COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi,34D8A@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WLSH3_k127_927584_2	311424.DhcVS_370	8.315e-64	222.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi,34CP6@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WLSH3_k127_944466_3	1227352.C173_31241	5.964e-05	49.0	COG1846@1|root,COG1846@2|Bacteria,1VBX8@1239|Firmicutes,4HKR1@91061|Bacilli,26WQZ@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	ywhA	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR
WLSH3_k127_944466_1	1379698.RBG1_1C00001G1619	2.316e-45	172.0	COG0785@1|root,COG0785@2|Bacteria,2NPE4@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein transmembrane region	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
WLSH3_k127_944466_2	255470.cbdbA600	1.059e-16	87.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,34DAG@301297|Dehalococcoidia	301297|Dehalococcoidia	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH3_k127_944466_0	1444309.JAQG01000008_gene1702	1.925e-140	454.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,26QJA@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH3_k127_9448488_0	243164.DET0510	2.129e-177	567.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi,34CP8@301297|Dehalococcoidia	301297|Dehalococcoidia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH3_k127_9448488_1	338966.Ppro_0472	9.444e-33	131.0	COG1014@1|root,COG1014@2|Bacteria,1N0EJ@1224|Proteobacteria,42UN6@68525|delta/epsilon subdivisions,2WQCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WLSH3_k127_9456648_1	479434.Sthe_2916	8.284e-83	277.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi,27YZB@189775|Thermomicrobia	189775|Thermomicrobia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WLSH3_k127_9456648_0	255470.cbdbA29	3.583e-91	318.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi,34CYA@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Domain of unknown function (DUF4131)	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WLSH3_k127_9456648_2	357808.RoseRS_1609	4.021e-50	195.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi,375B1@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ComEC Rec2-related protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
WLSH3_k127_9565720_3	1123290.AUDQ01000006_gene1800	1.144e-52	202.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,26EP7@186818|Planococcaceae	91061|Bacilli	S	Penicillin acylase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
WLSH3_k127_9565720_4	552811.Dehly_0132	1.172e-32	131.0	COG1324@1|root,COG1324@2|Bacteria,2G76K@200795|Chloroflexi,34DDG@301297|Dehalococcoidia	301297|Dehalococcoidia	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
WLSH3_k127_9565720_0	429009.Adeg_0424	2.19e-129	419.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,42F86@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
WLSH3_k127_9565720_1	552811.Dehly_0134	8.841e-82	279.0	COG1526@1|root,COG1526@2|Bacteria,2G74E@200795|Chloroflexi	200795|Chloroflexi	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
WLSH3_k127_9565720_2	877455.Metbo_1264	6.614e-53	190.0	COG2258@1|root,arCOG11383@2157|Archaea	2157|Archaea	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
WLSH3_k127_9565720_5	1123054.KB907704_gene1179	1.965e-26	121.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1WYFN@135613|Chromatiales	135613|Chromatiales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,HMA
WLSH3_k127_9565720_6	1322246.BN4_10851	1.109e-18	90.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42NHE@68525|delta/epsilon subdivisions,2WJPP@28221|Deltaproteobacteria,2M8KS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WLSH3_k127_9602936_14	1122918.KB907278_gene3983	1.732e-07	60.0	COG1846@1|root,COG1846@2|Bacteria,1VBX8@1239|Firmicutes,4HKR1@91061|Bacilli,26WQZ@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	ywhA	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR
WLSH3_k127_9602936_13	1048834.TC41_1976	3.607e-12	74.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WLSH3_k127_9602936_1	1128421.JAGA01000002_gene351	1.26e-106	352.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
WLSH3_k127_9602936_0	255470.cbdbA781	3.02e-112	368.0	COG0413@1|root,COG0413@2|Bacteria,2G5TQ@200795|Chloroflexi,34CNK@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
WLSH3_k127_9602936_8	552811.Dehly_0613	1.05e-40	154.0	COG0853@1|root,COG0853@2|Bacteria,2G6Z6@200795|Chloroflexi,34DAI@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
WLSH3_k127_9602936_7	255470.cbdbA779	3.537e-86	294.0	COG5495@1|root,COG5495@2|Bacteria,2G6F3@200795|Chloroflexi,34D9G@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,Rossmann-like
WLSH3_k127_9602936_3	762376.AXYL_05266	4.939e-99	332.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria	28216|Betaproteobacteria	EQ	PFAM peptidase S58, DmpA	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WLSH3_k127_9602936_5	552811.Dehly_0204	4.147e-92	311.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi,34D3S@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
WLSH3_k127_9602936_11	552811.Dehly_0203	2.141e-28	115.0	COG0254@1|root,COG0254@2|Bacteria,2G75A@200795|Chloroflexi,34DI6@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WLSH3_k127_9602936_10	309801.trd_1425	4.154e-29	118.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi,27YJD@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WLSH3_k127_9602936_12	635013.TherJR_2531	1.81e-26	111.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,262DA@186807|Peptococcaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WLSH3_k127_9602936_4	552811.Dehly_0379	1.67e-97	323.0	COG1611@1|root,COG1611@2|Bacteria,2G6IB@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WLSH3_k127_9602936_6	880072.Desac_1833	1.007e-87	297.0	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,42NBP@68525|delta/epsilon subdivisions,2WKS7@28221|Deltaproteobacteria,2MQCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
WLSH3_k127_9602936_2	1123274.KB899419_gene1986	4.642e-104	346.0	COG0190@1|root,COG0190@2|Bacteria,2J5PR@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WLSH3_k127_9602936_9	1121430.JMLG01000004_gene951	1.621e-35	136.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,2601Q@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WLSH3_k127_9607653_2	243164.DET0846	3.091e-55	204.0	COG0124@1|root,COG0124@2|Bacteria,2G962@200795|Chloroflexi,34CX8@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
WLSH3_k127_9607653_0	243164.DET0845	2.109e-131	434.0	COG0040@1|root,COG0040@2|Bacteria,2G6DD@200795|Chloroflexi,34CWY@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	-	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
WLSH3_k127_9607653_1	255470.cbdbA826	1.069e-82	284.0	COG0141@1|root,COG0141@2|Bacteria,2G5KP@200795|Chloroflexi,34D1N@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
WLSH3_k127_9784572_1	243164.DET1474	1.641e-64	224.0	COG0582@1|root,COG0582@2|Bacteria,2G7XX@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
WLSH3_k127_9784572_0	573370.DMR_34220	1.28e-279	863.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,42MIN@68525|delta/epsilon subdivisions,2WJC5@28221|Deltaproteobacteria,2M91H@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the catalase family	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
WLSH3_k127_9826050_1	693661.Arcve_1325	1.85e-51	198.0	COG0367@1|root,COG0449@1|root,arCOG00057@2157|Archaea,arCOG00071@2157|Archaea,2XSYP@28890|Euryarchaeota	28890|Euryarchaeota	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_6,GATase_7
WLSH3_k127_9826050_0	555088.DealDRAFT_2115	8.486e-57	203.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,42JQ4@68298|Syntrophomonadaceae	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
WLSH3_k127_9827102_3	111780.Sta7437_3644	0.0002535	46.0	COG0312@1|root,COG0312@2|Bacteria,1G0F3@1117|Cyanobacteria,3VI17@52604|Pleurocapsales	1117|Cyanobacteria	S	modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_9827102_0	552811.Dehly_0373	1.033e-75	264.0	COG2047@1|root,COG2047@2|Bacteria,2G9KI@200795|Chloroflexi,34CKE@301297|Dehalococcoidia	301297|Dehalococcoidia	S	PAC2 family	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
WLSH3_k127_9827102_1	479434.Sthe_0942	2.933e-72	248.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi,27XM8@189775|Thermomicrobia	189775|Thermomicrobia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH3_k127_9827102_2	311424.DhcVS_380	2.544e-50	182.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi,34CSJ@301297|Dehalococcoidia	301297|Dehalococcoidia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WLSH3_k127_9879929_1	909663.KI867150_gene1682	2.316e-40	149.0	COG0369@1|root,COG1151@2|Bacteria,1NRXN@1224|Proteobacteria,42Y5Y@68525|delta/epsilon subdivisions,2WUG6@28221|Deltaproteobacteria,2MSJ9@213462|Syntrophobacterales	2|Bacteria	P	Prismane/CO dehydrogenase family	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
WLSH3_k127_9879929_3	311424.DhcVS_879	2.558e-11	75.0	COG3599@1|root,COG3599@2|Bacteria,2GAMZ@200795|Chloroflexi,34CTV@301297|Dehalococcoidia	301297|Dehalococcoidia	D	DivIVA protein	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
WLSH3_k127_9879929_2	552811.Dehly_0786	1.782e-16	81.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	2.1.1.37	ko:K00558,ko:K13639,ko:K13640	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03000,ko03032,ko03036	-	-	-	DNA_methylase,MerR,MerR_1
WLSH3_k127_9879929_0	552811.Dehly_1197	1.47e-79	271.0	COG4826@1|root,COG4826@2|Bacteria,2GBWN@200795|Chloroflexi,34D50@301297|Dehalococcoidia	301297|Dehalococcoidia	M	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
WLSH3_k127_9891761_1	1403313.AXBR01000025_gene4893	3.133e-10	72.0	COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,1ZRKY@1386|Bacillus	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
WLSH3_k127_9891761_0	429009.Adeg_0882	2.358e-11	67.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,42EN4@68295|Thermoanaerobacterales	186801|Clostridia	E	homoserine dehydrogenase NAD-binding	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
WLSH3_k127_9900586_2	255470.cbdbA573	1.084e-79	270.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi,34CUM@301297|Dehalococcoidia	301297|Dehalococcoidia	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WLSH3_k127_9900586_3	1122611.KB903963_gene4826	1.977e-60	221.0	COG0491@1|root,COG0491@2|Bacteria,2GMDD@201174|Actinobacteria,4EG2C@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH3_k127_9900586_1	1304880.JAGB01000002_gene2026	6.32e-148	474.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WLSH3_k127_9900586_5	330214.NIDE4132	4.531e-22	98.0	COG1550@1|root,COG1550@2|Bacteria	2|Bacteria	H	Protein conserved in bacteria	ylxP	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
WLSH3_k127_9900586_0	552811.Dehly_0983	2.573e-250	793.0	COG0514@1|root,COG1205@1|root,COG0514@2|Bacteria,COG1205@2|Bacteria,2G605@200795|Chloroflexi,34CMG@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
WLSH3_k127_9900586_6	631362.Thi970DRAFT_02456	6.076e-17	86.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria,1WYD6@135613|Chromatiales	135613|Chromatiales	P	Belongs to the Fur family	-	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
WLSH3_k127_9900586_4	1047013.AQSP01000079_gene2038	1.402e-47	177.0	arCOG06621@1|root,33A1X@2|Bacteria,2NRVC@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9900586_7	1168034.FH5T_01550	0.0003703	43.0	COG1520@1|root,COG1520@2|Bacteria,4P1VG@976|Bacteroidetes,2FW8D@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
WLSH3_k127_9957488_2	552811.Dehly_1384	6.106e-17	84.0	COG1280@1|root,COG1280@2|Bacteria,2GBTY@200795|Chloroflexi,34CQW@301297|Dehalococcoidia	301297|Dehalococcoidia	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
WLSH3_k127_9957488_0	552811.Dehly_0137	9.106e-157	502.0	COG0516@1|root,COG0516@2|Bacteria,2G5ZX@200795|Chloroflexi,34CRY@301297|Dehalococcoidia	301297|Dehalococcoidia	C	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	IMPDH
WLSH3_k127_9957488_1	255470.cbdbA331	1.1e-65	228.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi,34CPU@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WLSH3_k127_9980706_1	186497.PF1078	7.53e-17	83.0	COG1906@1|root,arCOG04354@2157|Archaea,2XX2X@28890|Euryarchaeota,243P4@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
WLSH3_k127_9980706_0	1382306.JNIM01000001_gene251	1.253e-65	232.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi	200795|Chloroflexi	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WLSH3_k127_9991717_8	319225.Plut_1548	4.596e-08	56.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	metB_1	-	2.5.1.48,4.4.1.1,4.4.1.8	ko:K01739,ko:K01758,ko:K01760	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
WLSH3_k127_9991717_0	1255043.TVNIR_2757	4.997e-77	273.0	COG4591@1|root,COG4591@2|Bacteria,1R1KM@1224|Proteobacteria,1T554@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH3_k127_9991717_1	1123023.JIAI01000001_gene6735	1.139e-67	237.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DXK6@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_9991717_5	215803.DB30_0610	1.101e-17	94.0	COG2854@1|root,COG2854@2|Bacteria	2|Bacteria	Q	intermembrane phospholipid transfer	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
WLSH3_k127_9991717_6	330214.NIDE1819	2.864e-17	83.0	COG0498@1|root,COG0498@2|Bacteria,3J0FZ@40117|Nitrospirae	40117|Nitrospirae	E	Pyridoxal-phosphate dependent enzyme	thrC1	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WLSH3_k127_9991717_7	1162668.LFE_1737	6.787e-15	77.0	COG1135@1|root,COG1135@2|Bacteria,3J0VT@40117|Nitrospirae	40117|Nitrospirae	P	NIL	-	-	-	-	-	-	-	-	-	-	-	-	NIL
WLSH3_k127_9991717_4	1047013.AQSP01000092_gene322	1.544e-25	106.0	COG1104@1|root,COG1104@2|Bacteria,2NNVR@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
## 1111 queries scanned
## Total time (seconds): 3.2317328453063965
## Rate: 343.78 q/s