## Wed Dec 17 00:58:57 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/WLSH3_bin.72.fa -m mmseqs --itype genome -o WLSH3_bin.72 --output_dir /data/result/bins/wyx/egg/WLSH3_bin.72 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WLSH3_k127_10011819_1	290512.Paes_0669	7.041e-75	262.0	COG0475@1|root,COG0475@2|Bacteria,1FEIJ@1090|Chlorobi	1090|Chlorobi	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WLSH3_k127_10011819_0	1123368.AUIS01000003_gene1788	9.465e-76	265.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria	1224|Proteobacteria	P	COG0530 Ca2 Na antiporter	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WLSH3_k127_10011819_2	247490.KSU1_D0567	3.75e-13	74.0	COG1309@1|root,COG1309@2|Bacteria,2J28B@203682|Planctomycetes	203682|Planctomycetes	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WLSH3_k127_10030653_3	1268240.ATFI01000005_gene4678	0.0001318	46.0	2A5PA@1|root,30UE5@2|Bacteria,4P7BB@976|Bacteroidetes,2FVKX@200643|Bacteroidia,4ASKZ@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10030653_0	1379698.RBG1_1C00001G0627	4.887e-27	117.0	COG1595@1|root,COG1595@2|Bacteria,2NQ4E@2323|unclassified Bacteria	2|Bacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH3_k127_10030653_2	471852.Tcur_0599	6.907e-05	54.0	COG5662@1|root,COG5662@2|Bacteria,2GNCC@201174|Actinobacteria,4EKFN@85012|Streptosporangiales	201174|Actinobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WLSH3_k127_10030653_1	517418.Ctha_2329	1.011e-07	60.0	COG0810@1|root,COG0810@2|Bacteria,1FE18@1090|Chlorobi	1090|Chlorobi	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WLSH3_k127_10073110_0	1107311.Q767_10400	1.576e-77	267.0	COG2227@1|root,COG2227@2|Bacteria,4NF6D@976|Bacteroidetes,1HXVW@117743|Flavobacteriia,2NTAA@237|Flavobacterium	976|Bacteroidetes	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
WLSH3_k127_10073110_1	1226325.HMPREF1548_06888	6.433e-07	60.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K03217,ko:K08884	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02044,ko03029	2.A.9	-	-	60KD_IMP
WLSH3_k127_10093972_3	644968.DFW101_1691	2.616e-52	193.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2M9N8@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
WLSH3_k127_10093972_1	1121438.JNJA01000002_gene3541	3.29e-59	213.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2M9N8@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
WLSH3_k127_10093972_0	1047013.AQSP01000140_gene2548	3.604e-107	359.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH3_k127_10093972_2	880073.Calab_3019	1.077e-55	207.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
WLSH3_k127_10093972_4	1126627.BAWE01000004_gene4269	1.793e-11	67.0	COG4397@1|root,COG4397@2|Bacteria,1MWX8@1224|Proteobacteria,2U0B4@28211|Alphaproteobacteria,3K5FC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Mu-like prophage major head subunit gpT	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_gpT
WLSH3_k127_10123705_1	1379698.RBG1_1C00001G1783	7.751e-16	85.0	COG5448@1|root,COG5448@2|Bacteria,2NPPC@2323|unclassified Bacteria	2|Bacteria	S	Glycoside hydrolase family 24	-	-	-	-	-	-	-	-	-	-	-	-	DUF2460
WLSH3_k127_10123705_0	1379698.RBG1_1C00001G1785	9.006e-25	112.0	2EAWV@1|root,334Y2@2|Bacteria,2NRSF@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1018027_0	289376.THEYE_A1146	8.704e-94	328.0	COG0747@1|root,COG0747@2|Bacteria,3J134@40117|Nitrospirae	40117|Nitrospirae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH3_k127_1018027_1	925409.KI911562_gene300	3.744e-21	100.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1IQAA@117747|Sphingobacteriia	976|Bacteroidetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WLSH3_k127_10223522_0	269799.Gmet_2730	6.374e-98	330.0	COG0535@1|root,COG0535@2|Bacteria,1QWQ6@1224|Proteobacteria,43BV0@68525|delta/epsilon subdivisions,2X75Z@28221|Deltaproteobacteria,43U71@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WLSH3_k127_10238187_0	335541.Swol_2483	1.259e-120	402.0	COG2199@1|root,COG2202@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,42KYY@68298|Syntrophomonadaceae	186801|Clostridia	T	Diguanylate cyclase with PAS PAC sensor	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_3,PAS_4
WLSH3_k127_10238187_1	1118054.CAGW01000082_gene2952	1.207e-78	282.0	COG2027@1|root,COG2027@2|Bacteria,1TQFQ@1239|Firmicutes,4HA3X@91061|Bacilli,271XZ@186822|Paenibacillaceae	91061|Bacilli	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	dacC	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WLSH3_k127_10238187_2	404589.Anae109_2086	2.427e-13	71.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2YV8R@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WLSH3_k127_10241670_1	1499967.BAYZ01000090_gene4944	1.081e-36	143.0	COG1215@1|root,COG1215@2|Bacteria,2NRME@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH3_k127_10241670_0	386456.JQKN01000001_gene1782	1.796e-76	274.0	COG1032@1|root,arCOG01356@2157|Archaea,2XU04@28890|Euryarchaeota	28890|Euryarchaeota	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
WLSH3_k127_10246467_3	1206744.BAGL01000027_gene7372	3.366e-06	57.0	COG0500@1|root,COG2226@2|Bacteria,2GQCN@201174|Actinobacteria,4G221@85025|Nocardiaceae	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WLSH3_k127_10246467_2	309803.CTN_1455	9.532e-25	105.0	COG3450@1|root,COG3450@2|Bacteria,2GDFM@200918|Thermotogae	200918|Thermotogae	S	Enzyme of the cupin superfamily	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
WLSH3_k127_10246467_0	671143.DAMO_1647	6.639e-90	306.0	COG0673@1|root,COG0673@2|Bacteria,2NNUQ@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA
WLSH3_k127_10246467_1	56780.SYN_00663	6.279e-57	203.0	COG1751@1|root,COG1751@2|Bacteria,1RBXI@1224|Proteobacteria,42R3D@68525|delta/epsilon subdivisions,2WMRV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pyruvate kinase, alpha/beta domain	-	-	-	ko:K09126	-	-	-	-	ko00000	-	-	-	PK_C
WLSH3_k127_10313781_0	886293.Sinac_6081	2.617e-49	196.0	28M0D@1|root,2ZAFE@2|Bacteria,2IX4T@203682|Planctomycetes	203682|Planctomycetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
WLSH3_k127_10313781_1	867845.KI911784_gene311	1.591e-20	106.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
WLSH3_k127_10316241_1	1280686.AUKE01000006_gene401	7.318e-43	169.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,4BW4Z@830|Butyrivibrio	186801|Clostridia	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WLSH3_k127_10316241_0	526218.Sterm_4129	1.023e-149	487.0	COG1362@1|root,COG1362@2|Bacteria,378B1@32066|Fusobacteria	32066|Fusobacteria	E	M18 family aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
WLSH3_k127_10361628_1	243164.DET0526	1.917e-37	149.0	COG0312@1|root,COG0312@2|Bacteria,2GANY@200795|Chloroflexi,34CWZ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_10361628_0	237368.SCABRO_01041	1.509e-110	365.0	COG0312@1|root,COG0312@2|Bacteria,2J2IZ@203682|Planctomycetes	203682|Planctomycetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
WLSH3_k127_10379734_0	768670.Calni_0134	4.154e-29	118.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GEZG@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
WLSH3_k127_10379734_1	439235.Dalk_1582	0.0003953	53.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,2MP61@213118|Desulfobacterales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WLSH3_k127_10388881_1	1231057.AMGD01000104_gene265	4.949e-07	53.0	2EHF3@1|root,33B70@2|Bacteria,1VP4D@1239|Firmicutes,4HZXQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10388881_0	1379698.RBG1_1C00001G0456	1.491e-70	257.0	COG0760@1|root,COG0760@2|Bacteria,2NP7B@2323|unclassified Bacteria	2|Bacteria	O	Peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K01802,ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_2,SurA_N_3
WLSH3_k127_10417574_1	118005.AWNK01000002_gene1764	2.19e-34	138.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH3_k127_10417574_0	401526.TcarDRAFT_0209	2.44e-118	396.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4H2BC@909932|Negativicutes	909932|Negativicutes	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WLSH3_k127_10417574_2	255470.cbdbA721	2.853e-11	66.0	COG2426@1|root,COG2426@2|Bacteria,2GATG@200795|Chloroflexi,34DB2@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
WLSH3_k127_10420291_4	459349.CLOAM0692	7.081e-15	75.0	COG0614@1|root,COG0614@2|Bacteria,2NRFM@2323|unclassified Bacteria	2|Bacteria	P	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH3_k127_10420291_1	986075.CathTA2_0503	1.067e-45	174.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli	91061|Bacilli	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
WLSH3_k127_10420291_0	335541.Swol_2360	1.821e-57	204.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,42JZG@68298|Syntrophomonadaceae	186801|Clostridia	F	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
WLSH3_k127_10420291_3	945713.IALB_2261	6.015e-16	86.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	yngC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WLSH3_k127_10420291_2	314607.KB13_1288	5.283e-30	121.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,1KQZD@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WLSH3_k127_10449141_1	771875.Ferpe_0851	1.108e-13	72.0	COG2344@1|root,COG2344@2|Bacteria,2GCZC@200918|Thermotogae	200918|Thermotogae	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WLSH3_k127_10449141_0	1379698.RBG1_1C00001G0684	1.353e-151	492.0	COG0277@1|root,COG0277@2|Bacteria,2NP1E@2323|unclassified Bacteria	2|Bacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.3.15	ko:K00104,ko:K18930	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
WLSH3_k127_1045306_0	648996.Theam_0136	1.184e-89	305.0	COG0740@1|root,COG0740@2|Bacteria,2G3IM@200783|Aquificae	200783|Aquificae	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WLSH3_k127_1045306_2	1168034.FH5T_02060	5.491e-11	68.0	COG2827@1|root,COG2827@2|Bacteria,4P9EH@976|Bacteroidetes,2FZ8T@200643|Bacteroidia	976|Bacteroidetes	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH3_k127_1045306_1	517418.Ctha_0299	1.787e-29	123.0	COG4254@1|root,COG4254@2|Bacteria,1FEZE@1090|Chlorobi	1090|Chlorobi	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10501539_5	1232452.BAIB02000003_gene402	1.543e-09	61.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,26832@186813|unclassified Clostridiales	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
WLSH3_k127_10501539_3	1121920.AUAU01000017_gene1212	4.222e-26	112.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	2.8.1.1,2.8.1.2	ko:K00406,ko:K01011	ko00190,ko00270,ko00920,ko01100,ko01120,ko02020,ko04122,map00190,map00270,map00920,map01100,map01120,map02020,map04122	M00156	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3,PALP,Rhodanese
WLSH3_k127_10501539_0	697282.Mettu_2925	3.907e-165	525.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,1XF21@135618|Methylococcales	135618|Methylococcales	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WLSH3_k127_10501539_4	909663.KI867150_gene292	9.514e-23	101.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42VSP@68525|delta/epsilon subdivisions,2WRGT@28221|Deltaproteobacteria,2MSJQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WLSH3_k127_10501539_1	945713.IALB_2926	5.115e-122	394.0	COG0588@1|root,COG0588@2|Bacteria	2|Bacteria	G	phosphoglycerate mutase activity	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WLSH3_k127_10501539_2	555088.DealDRAFT_2075	3.511e-29	122.0	arCOG03165@1|root,30AIC@2|Bacteria,1V7NB@1239|Firmicutes,24M5X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10511870_2	459349.CLOAM1383	1.378e-14	84.0	COG2825@1|root,COG2825@2|Bacteria,2NQ6C@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane protein (OmpH-like)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
WLSH3_k127_10511870_0	1125863.JAFN01000001_gene3410	3.229e-93	317.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
WLSH3_k127_10511870_1	869213.JCM21142_83238	2.66e-86	289.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,47KN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WLSH3_k127_10542971_0	880072.Desac_2335	6.926e-43	173.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2MQKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WLSH3_k127_10542971_3	1121422.AUMW01000017_gene1971	2.318e-22	110.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,26736@186807|Peptococcaceae	186801|Clostridia	T	response regulator receiver	walR	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_10542971_1	526222.Desal_3269	1.775e-34	134.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,42VQ4@68525|delta/epsilon subdivisions,2WS47@28221|Deltaproteobacteria,2MGUU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	PFAM Methylated-DNA- protein -cysteine	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
WLSH3_k127_10542971_2	357808.RoseRS_1337	1.669e-30	122.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,375BD@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH3_k127_10547673_1	1379698.RBG1_1C00001G1161	1.855e-115	385.0	COG0612@1|root,COG0612@2|Bacteria,2NNW3@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the peptidase M16 family	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH3_k127_10547673_0	880073.Calab_3657	3.738e-164	533.0	COG0608@1|root,COG0608@2|Bacteria,2NNRX@2323|unclassified Bacteria	2|Bacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH3_k127_10547673_6	272624.lpg1742	8.203e-05	51.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria,1JFBK@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10547673_3	237368.SCABRO_02434	1.139e-28	122.0	COG0328@1|root,COG0328@2|Bacteria,2J0TM@203682|Planctomycetes	203682|Planctomycetes	L	Reverse transcriptase-like	-	-	-	-	-	-	-	-	-	-	-	-	RVT_3
WLSH3_k127_10547673_4	880073.Calab_3658	1.969e-25	115.0	COG1579@1|root,COG1579@2|Bacteria,2NPW0@2323|unclassified Bacteria	2|Bacteria	S	C4-type zinc ribbon domain	CP_0228	-	3.5.4.16	ko:K07164,ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	zf-RING_7
WLSH3_k127_10547673_5	1211814.CAPG01000021_gene798	7.001e-10	68.0	COG1309@1|root,COG1309@2|Bacteria,1V8TI@1239|Firmicutes,4HNCJ@91061|Bacilli,1ZIP0@1386|Bacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH3_k127_10547673_2	81824.XP_001747097.1	1.858e-37	160.0	29QRV@1|root,2RX97@2759|Eukaryota,38CMN@33154|Opisthokonta	2759|Eukaryota	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
WLSH3_k127_10570194_0	644282.Deba_2541	6.188e-45	166.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42U5G@68525|delta/epsilon subdivisions,2WQ28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH3_k127_10570194_2	1047013.AQSP01000066_gene720	7.078e-35	144.0	COG0457@1|root,COG0457@2|Bacteria	1047013.AQSP01000066_gene720|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10570194_1	203124.Tery_4688	2.741e-42	164.0	COG1277@1|root,COG1277@2|Bacteria,1G09F@1117|Cyanobacteria,1H81Z@1150|Oscillatoriales	1117|Cyanobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
WLSH3_k127_10570194_3	290397.Adeh_0636	6.734e-32	129.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YXY8@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_10593823_2	880073.Calab_2841	5.879e-35	149.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
WLSH3_k127_10593823_3	880073.Calab_0651	2.703e-27	126.0	COG1629@1|root,COG4771@2|Bacteria,2NP6Z@2323|unclassified Bacteria	2|Bacteria	P	COGs COG1629 Outer membrane receptor protein mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WLSH3_k127_10593823_1	269798.CHU_2160	8.748e-116	385.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,47M1S@768503|Cytophagia	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
WLSH3_k127_10593823_0	880073.Calab_3177	3.765e-133	445.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WLSH3_k127_10619961_1	1191523.MROS_0942	1.652e-50	191.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH3_k127_10619961_0	1191523.MROS_0941	7.228e-104	345.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH3_k127_10619961_2	518766.Rmar_1779	1.266e-08	61.0	COG1538@1|root,COG1538@2|Bacteria,4NDZ6@976|Bacteroidetes	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WLSH3_k127_10630383_3	309801.trd_0355	5.796e-05	52.0	COG2912@1|root,COG2912@2|Bacteria,2GBGR@200795|Chloroflexi,27YFQ@189775|Thermomicrobia	189775|Thermomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1
WLSH3_k127_10630383_0	316067.Geob_3104	3.646e-104	353.0	COG1625@1|root,COG1625@2|Bacteria,1R76F@1224|Proteobacteria	1224|Proteobacteria	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
WLSH3_k127_10630383_2	880073.Calab_3019	1.325e-20	102.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
WLSH3_k127_10630383_1	1123368.AUIS01000004_gene271	1.005e-59	214.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,1RNZC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Gram-negative-bacterium-type cell wall biogenesis	ycbC	GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	DUF218
WLSH3_k127_10647808_0	1499967.BAYZ01000114_gene2902	4.076e-117	383.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WLSH3_k127_10647808_1	572546.Arcpr_1334	2.806e-69	241.0	COG0563@1|root,arCOG01046@2157|Archaea,2XTRG@28890|Euryarchaeota,246UX@183980|Archaeoglobi	183980|Archaeoglobi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WLSH3_k127_10647808_2	926550.CLDAP_03880	1.611e-34	136.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi	200795|Chloroflexi	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WLSH3_k127_10655352_3	1392498.JQLH01000001_gene724	1.173e-10	63.0	COG0632@1|root,COG0632@2|Bacteria,4NF4E@976|Bacteroidetes,1HX6W@117743|Flavobacteriia,2PH3Y@252356|Maribacter	976|Bacteroidetes	L	RuvA, C-terminal domain	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WLSH3_k127_10655352_1	1121878.AUGL01000021_gene2773	3.206e-41	157.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WLSH3_k127_10655352_0	1499967.BAYZ01000068_gene1977	2.503e-104	344.0	COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WLSH3_k127_10655352_2	1120959.ATXF01000007_gene2342	3.848e-12	73.0	COG2890@1|root,COG2890@2|Bacteria,2GJPP@201174|Actinobacteria,4FM16@85023|Microbacteriaceae	201174|Actinobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	rsmC	-	-	-	-	-	-	-	-	-	-	-	MTS
WLSH3_k127_10666729_0	1265503.KB905161_gene3380	3.957e-91	315.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria,2Q809@267889|Colwelliaceae	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	wzxC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328,ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2,2.A.66.2.7	-	-	Polysacc_synt_3,Polysacc_synt_C
WLSH3_k127_10666729_5	1166018.FAES_5461	4.423e-73	260.0	COG0438@1|root,COG0438@2|Bacteria,4PC5J@976|Bacteroidetes,47WUR@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WLSH3_k127_10666729_6	756272.Plabr_1309	1.652e-69	244.0	COG1216@1|root,COG1216@2|Bacteria,2J51B@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH3_k127_10666729_8	387093.SUN_1538	4.417e-17	88.0	COG2456@1|root,COG2456@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	XK27_09090	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
WLSH3_k127_10666729_3	1232410.KI421412_gene225	6.855e-81	279.0	COG0463@1|root,COG2456@1|root,COG0463@2|Bacteria,COG2456@2|Bacteria,1QW3P@1224|Proteobacteria,42QT7@68525|delta/epsilon subdivisions,2WPEZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2304,Glycos_transf_2
WLSH3_k127_10666729_4	240292.Ava_1042	7.038e-81	276.0	COG1216@1|root,COG1216@2|Bacteria,1G2TX@1117|Cyanobacteria	1117|Cyanobacteria	Q	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_10666729_1	240292.Ava_1043	1.13e-83	284.0	COG2244@1|root,COG2244@2|Bacteria,1GR0U@1117|Cyanobacteria,1HQBS@1161|Nostocales	1117|Cyanobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
WLSH3_k127_10666729_2	471854.Dfer_2209	7.402e-83	284.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20,Methyltransf_21,Methyltransf_24
WLSH3_k127_10666729_7	82654.Pse7367_3029	3.233e-20	99.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria	2|Bacteria	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41
WLSH3_k127_10690064_4	247490.KSU1_D0467	3.043e-05	55.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WLSH3_k127_10690064_0	1379698.RBG1_1C00001G0646	5.328e-318	990.0	COG0466@1|root,COG0466@2|Bacteria,2NNNN@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WLSH3_k127_10690064_2	264732.Moth_2505	3.813e-13	75.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24U24@186801|Clostridia,42GM9@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH3_k127_10690064_3	1395587.P364_0113890	2.683e-12	71.0	COG1813@1|root,COG1813@2|Bacteria,1VEVE@1239|Firmicutes,4ITB7@91061|Bacilli,277T1@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WLSH3_k127_10690064_1	1121468.AUBR01000023_gene2755	2.077e-54	200.0	COG0665@1|root,COG0665@2|Bacteria,1VTRW@1239|Firmicutes,25F1Y@186801|Clostridia,42GRB@68295|Thermoanaerobacterales	186801|Clostridia	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
WLSH3_k127_10698911_0	880073.Calab_2813	1.295e-97	336.0	COG1480@1|root,COG1480@2|Bacteria,2NP1K@2323|unclassified Bacteria	2|Bacteria	S	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
WLSH3_k127_10698911_2	1121430.JMLG01000001_gene2256	7.11e-26	111.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,2620D@186807|Peptococcaceae	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
WLSH3_k127_10698911_1	1321778.HMPREF1982_04612	7.212e-90	312.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,267YU@186813|unclassified Clostridiales	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WLSH3_k127_10698911_3	926569.ANT_05030	2.961e-14	74.0	COG4843@1|root,COG4843@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
WLSH3_k127_10710023_1	1121904.ARBP01000012_gene1352	6.131e-25	107.0	COG1462@1|root,COG1462@2|Bacteria,4NZTS@976|Bacteroidetes	976|Bacteroidetes	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
WLSH3_k127_10710023_0	1121904.ARBP01000012_gene1352	1.798e-40	156.0	COG1462@1|root,COG1462@2|Bacteria,4NZTS@976|Bacteroidetes	976|Bacteroidetes	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
WLSH3_k127_10710023_3	439292.Bsel_0659	3.622e-06	57.0	COG4254@1|root,COG4733@1|root,COG4254@2|Bacteria,COG4733@2|Bacteria,1VJQE@1239|Firmicutes,4HZ8Y@91061|Bacilli	91061|Bacilli	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WLSH3_k127_10743744_1	545243.BAEV01000010_gene1113	1.93e-98	328.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
WLSH3_k127_10743744_0	555088.DealDRAFT_2165	6.597e-156	505.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42JHA@68298|Syntrophomonadaceae	186801|Clostridia	J	elongation factor Tu domain 2 protein	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH3_k127_10743744_3	1209989.TepiRe1_2353	7.586e-55	199.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42FPS@68295|Thermoanaerobacterales	186801|Clostridia	J	TIGRFAM Translation elongation factor	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WLSH3_k127_10743744_4	1289135.A966_02213	1.055e-21	102.0	COG0840@1|root,COG0840@2|Bacteria,2J5BF@203691|Spirochaetes	203691|Spirochaetes	NT	methyl-accepting chemotaxis protein	mcp2	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
WLSH3_k127_10743744_2	459349.CLOAM1502	6.628e-63	231.0	COG0750@1|root,COG0750@2|Bacteria,2NP7C@2323|unclassified Bacteria	2|Bacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
WLSH3_k127_1075266_0	869213.JCM21142_83238	9.588e-170	539.0	COG3033@1|root,COG3033@2|Bacteria,4NEP4@976|Bacteroidetes,47KN6@768503|Cytophagia	976|Bacteroidetes	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WLSH3_k127_1075266_1	439235.Dalk_0325	1.261e-40	156.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42R9X@68525|delta/epsilon subdivisions,2WMW8@28221|Deltaproteobacteria,2MKJP@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WLSH3_k127_10807917_3	1122221.JHVI01000007_gene2155	2.517e-133	436.0	COG0438@1|root,COG0438@2|Bacteria,1WKTB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH3_k127_10807917_9	926561.KB900617_gene2096	4.263e-23	113.0	COG3307@1|root,COG3307@2|Bacteria,1UVB1@1239|Firmicutes,25K69@186801|Clostridia,3WBBZ@53433|Halanaerobiales	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WLSH3_k127_10807917_8	357808.RoseRS_3578	1.965e-52	190.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,374ZJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WLSH3_k127_10807917_7	330214.NIDE0884	2.589e-65	231.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	rhiI	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944	-	ko:K15471	-	-	-	-	ko00000,ko01000,ko01008	-	-	-	Methyltransf_11,Methyltransf_25
WLSH3_k127_10807917_0	697281.Mahau_0321	1.438e-188	608.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,42EJW@68295|Thermoanaerobacterales	186801|Clostridia	GM	PFAM Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
WLSH3_k127_10807917_2	479434.Sthe_2756	3.587e-139	452.0	COG0399@1|root,COG0399@2|Bacteria,2G7XI@200795|Chloroflexi	200795|Chloroflexi	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WLSH3_k127_10807917_6	909663.KI867150_gene1635	1.682e-69	240.0	COG0110@1|root,COG0110@2|Bacteria,1PFB8@1224|Proteobacteria,439Z7@68525|delta/epsilon subdivisions,2X1Z1@28221|Deltaproteobacteria,2MSCA@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WLSH3_k127_10807917_5	632518.Calow_0495	8.74e-78	273.0	COG2222@1|root,COG2222@2|Bacteria,1TRBS@1239|Firmicutes,24A9W@186801|Clostridia,42EVQ@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM bifunctional phosphoglucose phosphomannose isomerase	-	-	5.3.1.8,5.3.1.9	ko:K15916	ko00010,ko00030,ko00051,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R01819,R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS,bact-PGI_C
WLSH3_k127_10807917_4	1519464.HY22_02585	5.812e-103	347.0	COG1209@1|root,COG1209@2|Bacteria,1FD8Z@1090|Chlorobi	1090|Chlorobi	M	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WLSH3_k127_10807917_1	1041930.Mtc_2312	2.493e-176	559.0	COG0192@1|root,arCOG07444@2157|Archaea	2157|Archaea	H	S-adenosylmethionine synthetase, C-terminal domain	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WLSH3_k127_10807917_10	247490.KSU1_D0387	2.192e-09	58.0	COG0499@1|root,COG0499@2|Bacteria,2IXKQ@203682|Planctomycetes	203682|Planctomycetes	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WLSH3_k127_10854791_2	1265505.ATUG01000003_gene849	1.016e-93	317.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,42ND4@68525|delta/epsilon subdivisions,2WKQP@28221|Deltaproteobacteria,2MMYU@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WLSH3_k127_10854791_4	1121904.ARBP01000014_gene74	9.606e-09	65.0	COG3637@1|root,COG3637@2|Bacteria,4NRJW@976|Bacteroidetes,47PGW@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
WLSH3_k127_10854791_0	344747.PM8797T_10544	6.32e-135	441.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
WLSH3_k127_10854791_3	926692.AZYG01000067_gene2078	3.392e-72	252.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,3WBHR@53433|Halanaerobiales	186801|Clostridia	S	DNA polymerase alpha chain like domain	trpH	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
WLSH3_k127_10854791_1	290397.Adeh_0652	1.167e-96	324.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42MM0@68525|delta/epsilon subdivisions,2WKXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
WLSH3_k127_10856423_1	741091.Rahaq_2251	7.797e-92	316.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,3FF7M@34037|Rahnella	1236|Gammaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	wcaA	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
WLSH3_k127_10856423_0	1496688.ER33_07095	9.06e-106	353.0	COG2379@1|root,COG2379@2|Bacteria,1G810@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
WLSH3_k127_10893148_4	456442.Mboo_1358	1.793e-08	58.0	COG0457@1|root,COG0784@1|root,arCOG03032@2157|Archaea,arCOG06537@2157|Archaea,2XWYJ@28890|Euryarchaeota,2NAS2@224756|Methanomicrobia	224756|Methanomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9,Response_reg
WLSH3_k127_10893148_2	401526.TcarDRAFT_2094	2.475e-66	231.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4H3ZG@909932|Negativicutes	909932|Negativicutes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
WLSH3_k127_10893148_1	309799.DICTH_1465	6.264e-122	398.0	COG0540@1|root,COG0540@2|Bacteria	2|Bacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00608,ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15490	OTCace,OTCace_N
WLSH3_k127_10893148_0	635013.TherJR_1832	7.534e-140	471.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WLSH3_k127_10893148_3	290315.Clim_1173	1.329e-54	197.0	COG3808@1|root,COG3808@2|Bacteria,1FD6P@1090|Chlorobi	1090|Chlorobi	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
WLSH3_k127_10914854_3	1242864.D187_004631	2.129e-31	125.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
WLSH3_k127_10914854_0	649747.HMPREF0083_00886	5.846e-99	329.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,26SPV@186822|Paenibacillaceae	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	iSB619.SA_RS06920	ABC_tran
WLSH3_k127_10914854_1	247490.KSU1_B0729	1.11e-63	225.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WLSH3_k127_10914854_2	926550.CLDAP_35050	3.418e-43	160.0	COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi	200795|Chloroflexi	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_5,LMWPc
WLSH3_k127_10918880_6	153721.MYP_1174	6.811e-09	60.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,47SBH@768503|Cytophagia	976|Bacteroidetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WLSH3_k127_10918880_4	269796.Rru_A0319	1.037e-27	121.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2UHD9@28211|Alphaproteobacteria,2JXQX@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q2
WLSH3_k127_10918880_7	391612.CY0110_22976	2.883e-07	58.0	COG0659@1|root,COG0664@1|root,COG2066@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,COG2066@2|Bacteria,1G1IK@1117|Cyanobacteria,3KH5H@43988|Cyanothece	1117|Cyanobacteria	E	Belongs to the glutaminase family	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase,STAS,cNMP_binding
WLSH3_k127_10918880_0	269796.Rru_A0320	1.211e-100	346.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2UQND@28211|Alphaproteobacteria,2JZPC@204441|Rhodospirillales	204441|Rhodospirillales	C	Proton-conducting membrane transporter	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WLSH3_k127_10918880_1	671143.DAMO_1398	1.783e-83	292.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livK	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iECNA114_1301.ECNA114_3569,iECSF_1327.ECSF_3279,iECs_1301.ECs4309,iEcSMS35_1347.EcSMS35_3743,iG2583_1286.G2583_4163,iSFxv_1172.SFxv_3794,iSSON_1240.SSON_3698,iS_1188.S4285,iUTI89_1310.UTI89_C3965,iYL1228.KPN_03820,iZ_1308.Z4834	Peripla_BP_6
WLSH3_k127_10918880_2	1123376.AUIU01000014_gene596	1.422e-62	218.0	COG3260@1|root,COG3260@2|Bacteria,3J0NM@40117|Nitrospirae	40117|Nitrospirae	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
WLSH3_k127_10918880_5	1121456.ATVA01000002_gene3176	1.388e-13	82.0	COG3221@1|root,COG3221@2|Bacteria,1NPBT@1224|Proteobacteria,42NX8@68525|delta/epsilon subdivisions,2WM7I@28221|Deltaproteobacteria,2M8QC@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
WLSH3_k127_10918880_3	1041930.Mtc_2125	2.686e-51	203.0	COG0243@1|root,arCOG01492@2157|Archaea,2Y8AB@28890|Euryarchaeota,2N977@224756|Methanomicrobia	224756|Methanomicrobia	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WLSH3_k127_10965934_2	762968.HMPREF9441_00862	8.738e-06	57.0	2DMY7@1|root,32UCK@2|Bacteria,4NSK3@976|Bacteroidetes,2FUCG@200643|Bacteroidia	976|Bacteroidetes	S	Outer membrane protein Omp28	-	-	-	-	-	-	-	-	-	-	-	-	Omp28
WLSH3_k127_10965934_0	945713.IALB_2658	1.91e-28	121.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH3_k127_10965934_1	660470.Theba_2008	2.758e-10	63.0	COG1409@1|root,COG1409@2|Bacteria,2GDAI@200918|Thermotogae	200918|Thermotogae	P	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WLSH3_k127_10977375_1	278963.ATWD01000001_gene3847	5.048e-44	183.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria,2JKR9@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
WLSH3_k127_10977375_0	682795.AciX8_2124	1.327e-148	488.0	COG0312@1|root,COG0312@2|Bacteria,3Y3MT@57723|Acidobacteria,2JKR9@204432|Acidobacteriia	57723|Acidobacteria	S	PFAM peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
WLSH3_k127_10992406_0	195522.BD01_1876	7.47e-60	215.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota,242IJ@183968|Thermococci	183968|Thermococci	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_10992406_1	1379698.RBG1_1C00001G1508	1.034e-39	149.0	2E4KV@1|root,32ZFU@2|Bacteria,2NQ0D@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
WLSH3_k127_10992406_2	215803.DB30_6644	8.245e-27	115.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2WT4M@28221|Deltaproteobacteria,2YVRK@29|Myxococcales	28221|Deltaproteobacteria	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
WLSH3_k127_11037675_0	671143.DAMO_0294	5.806e-49	185.0	COG0500@1|root,COG0535@1|root,COG0535@2|Bacteria,COG2226@2|Bacteria,2NPMF@2323|unclassified Bacteria	2|Bacteria	Q	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Methyltransf_11,Methyltransf_25,Radical_SAM,SPASM
WLSH3_k127_11037675_2	926550.CLDAP_00360	3.913e-22	108.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
WLSH3_k127_11037675_1	880073.Calab_2181	2.678e-41	156.0	COG0535@1|root,COG0535@2|Bacteria,2NPKA@2323|unclassified Bacteria	2|Bacteria	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WLSH3_k127_1107078_1	857293.CAAU_0169	7.45e-66	230.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,36DMV@31979|Clostridiaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
WLSH3_k127_1107078_2	1379698.RBG1_1C00001G0556	7.435e-45	173.0	COG1463@1|root,COG1463@2|Bacteria,2NPXB@2323|unclassified Bacteria	2|Bacteria	Q	MlaD protein	ttg2C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WLSH3_k127_1107078_3	1009370.ALO_00550	3.165e-21	102.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes	1239|Firmicutes	I	Psort location CytoplasmicMembrane, score	pgpB	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WLSH3_k127_1107078_0	1121289.JHVL01000002_gene2427	1.103e-72	255.0	COG1142@1|root,COG2878@1|root,COG1142@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,36FC4@31979|Clostridiaceae	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
WLSH3_k127_1107078_6	639282.DEFDS_0491	2.944e-05	56.0	COG4657@1|root,COG4657@2|Bacteria,2GETG@200930|Deferribacteres	200930|Deferribacteres	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
WLSH3_k127_1107078_5	589865.DaAHT2_0045	1.398e-07	61.0	COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,42QT5@68525|delta/epsilon subdivisions,2WN1N@28221|Deltaproteobacteria,2MHSZ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	-	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
WLSH3_k127_1107078_4	1379698.RBG1_1C00001G0415	7.097e-14	73.0	COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
WLSH3_k127_11107445_2	582402.Hbal_2535	8.963e-05	47.0	COG0810@1|root,COG0810@2|Bacteria,1PGBZ@1224|Proteobacteria,2V7CS@28211|Alphaproteobacteria,43ZMW@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WLSH3_k127_11107445_0	269797.Mbar_A0185	4.356e-111	369.0	COG0037@1|root,arCOG15275@2157|Archaea,2Y0EE@28890|Euryarchaeota,2NB74@224756|Methanomicrobia	224756|Methanomicrobia	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	QueC
WLSH3_k127_11107445_1	1123368.AUIS01000010_gene2337	6.495e-53	198.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,2NCGS@225057|Acidithiobacillales	225057|Acidithiobacillales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
WLSH3_k127_11107838_0	880073.Calab_2356	6.834e-252	798.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
WLSH3_k127_11107838_1	1158294.JOMI01000001_gene1430	2.549e-51	186.0	COG0574@1|root,COG0745@1|root,COG0574@2|Bacteria,COG0745@2|Bacteria,4NGSQ@976|Bacteroidetes,2FM60@200643|Bacteroidia	976|Bacteroidetes	GKT	Pyruvate phosphate dikinase, PEP pyruvate binding domain	ppsA	-	-	-	-	-	-	-	-	-	-	-	PPDK_N,Response_reg
WLSH3_k127_11134252_2	1379698.RBG1_1C00001G1629	2.948e-72	259.0	COG0037@1|root,COG0037@2|Bacteria,2NPAZ@2323|unclassified Bacteria	2|Bacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
WLSH3_k127_11134252_4	1128398.Curi_c23680	3.392e-61	218.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WLSH3_k127_11134252_0	1379698.RBG1_1C00001G1627	5.774e-246	775.0	COG0465@1|root,COG0465@2|Bacteria,2NNQ5@2323|unclassified Bacteria	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WLSH3_k127_11134252_3	635013.TherJR_1931	5.673e-67	234.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,25ZXN@186807|Peptococcaceae	186801|Clostridia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WLSH3_k127_11134252_1	289376.THEYE_A0627	1.257e-92	312.0	COG0294@1|root,COG0294@2|Bacteria,3J0NS@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WLSH3_k127_11161096_2	439481.Aboo_0158	1.067e-101	340.0	COG0448@1|root,arCOG00912@2157|Archaea,2XTI4@28890|Euryarchaeota,3F2GM@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	aspartate ornithine carbamoyltransferase carbamoyl-P binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WLSH3_k127_11161096_1	457570.Nther_2455	3.514e-119	394.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia	186801|Clostridia	E	PFAM Cys Met metabolism	megL	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WLSH3_k127_11161096_0	511051.CSE_10380	2.94e-137	449.0	COG1883@1|root,COG1883@2|Bacteria	2|Bacteria	C	oxaloacetate decarboxylase activity	gcdB	-	4.1.1.3,4.1.1.70	ko:K01572,ko:K01615	ko00362,ko00620,ko00650,ko01100,ko01120,map00362,map00620,map00650,map01100,map01120	-	R00217,R03028	RC00040,RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1,3.B.1.1.3	-	-	OAD_beta
WLSH3_k127_11161096_3	697281.Mahau_1319	4.536e-60	212.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,42FKR@68295|Thermoanaerobacterales	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
WLSH3_k127_11288283_3	1370122.JHXQ01000004_gene2497	2.604e-05	56.0	COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,2TUFD@28211|Alphaproteobacteria,4B7NU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Polysacc_deac_2
WLSH3_k127_11288283_0	1408473.JHXO01000004_gene220	3.114e-97	354.0	COG0729@1|root,COG1752@1|root,COG0729@2|Bacteria,COG1752@2|Bacteria,4NDXY@976|Bacteroidetes,2FNEV@200643|Bacteroidia	976|Bacteroidetes	M	Phospholipase, patatin family	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	POTRA,Patatin
WLSH3_k127_11288283_1	1392502.JNIO01000008_gene3004	2.319e-39	148.0	COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H4QP@909932|Negativicutes	909932|Negativicutes	K	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
WLSH3_k127_11288283_2	1410608.JNKX01000020_gene51	1.043e-09	59.0	COG2220@1|root,COG2220@2|Bacteria,4NFJ4@976|Bacteroidetes,2FNMD@200643|Bacteroidia,4AQS7@815|Bacteroidaceae	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
WLSH3_k127_11299773_0	1379698.RBG1_1C00001G1210	4.929e-96	332.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH3_k127_11322926_4	794903.OPIT5_13320	0.0005617	48.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia,3K74G@414999|Opitutae	414999|Opitutae	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_11322926_2	1232437.KL661954_gene2353	7.876e-53	187.0	COG0437@1|root,COG0437@2|Bacteria,1NF8S@1224|Proteobacteria,42WBD@68525|delta/epsilon subdivisions,2WRT3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
WLSH3_k127_11322926_0	1232410.KI421421_gene3246	0.0	1185.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,43TBB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WLSH3_k127_11322926_3	1232437.KL662077_gene1877	3.344e-38	150.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	badR	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
WLSH3_k127_11322926_1	525897.Dbac_0704	6.965e-205	642.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,2M8ZB@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_11384026_1	1150474.JQJI01000037_gene1996	1.629e-05	48.0	COG2137@1|root,COG2137@2|Bacteria,2GDGP@200918|Thermotogae	200918|Thermotogae	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WLSH3_k127_11384026_0	1379698.RBG1_1C00001G1888	6.246e-145	467.0	COG0468@1|root,COG0468@2|Bacteria,2NNYW@2323|unclassified Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WLSH3_k127_11384026_2	1411685.U062_02354	2.906e-05	52.0	COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,1RMGH@1236|Gammaproteobacteria,1J4IB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
WLSH3_k127_11389120_2	330214.NIDE4157	3.621e-23	103.0	COG3824@1|root,COG3824@2|Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
WLSH3_k127_11389120_0	459349.CLOAM0977	3.229e-83	284.0	COG0730@1|root,COG0730@2|Bacteria,2NPXM@2323|unclassified Bacteria	2|Bacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WLSH3_k127_11389120_1	269799.Gmet_0697	5.187e-70	243.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WLSH3_k127_11408581_0	545695.TREAZ_0506	8.475e-125	416.0	COG3829@1|root,COG3829@2|Bacteria,2J63K@203691|Spirochaetes	203691|Spirochaetes	KT	Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
WLSH3_k127_11408581_1	883081.HMPREF9698_01013	1.005e-46	173.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli,27FMR@186828|Carnobacteriaceae	91061|Bacilli	L	UvrD-like helicase C-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH3_k127_11507105_0	56780.SYN_03628	9.998e-111	364.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,2MQ6Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
WLSH3_k127_11507105_1	316067.Geob_1006	2.447e-31	126.0	COG0784@1|root,COG0784@2|Bacteria,1N017@1224|Proteobacteria,42UW8@68525|delta/epsilon subdivisions,2X7PA@28221|Deltaproteobacteria,43W1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH3_k127_11507105_2	593105.S7A_03170	4.933e-06	49.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,1RMZT@1236|Gammaproteobacteria,3VZZ3@53335|Pantoea	1236|Gammaproteobacteria	T	Histidine kinase	kdpD	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0008134,GO:0008150,GO:0008152,GO:0009593,GO:0009605,GO:0009628,GO:0009651,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031668,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051606,GO:0051716,GO:0065007,GO:0071214,GO:0071470,GO:0071472,GO:0071496,GO:0071704,GO:0071944,GO:0104004,GO:0140096,GO:1901564	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
WLSH3_k127_11545123_2	1121468.AUBR01000015_gene2267	3.289e-23	102.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,42F8Y@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM TrkA-N domain protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WLSH3_k127_11545123_0	1089548.KI783301_gene1465	2.014e-117	398.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli,3WFFD@539002|Bacillales incertae sedis	91061|Bacilli	P	Cation transport protein	ktrB1	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WLSH3_k127_11545123_3	1121406.JAEX01000005_gene3078	5.065e-22	103.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2MC5C@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
WLSH3_k127_11545123_1	215803.DB30_5679	2.478e-38	147.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WLSH3_k127_11568895_2	416591.Tlet_1547	1.869e-35	139.0	COG1175@1|root,COG1175@2|Bacteria,2GCID@200918|Thermotogae	200918|Thermotogae	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH3_k127_11568895_1	1034347.CAHJ01000032_gene4110	1.541e-74	261.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,1ZQ4W@1386|Bacillus	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	malF	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WLSH3_k127_11568895_0	459349.CLOAM0889	3.119e-95	328.0	COG1653@1|root,COG1653@2|Bacteria,2NPYG@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein	malE	-	-	ko:K02027,ko:K05813	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	SBP_bac_8
WLSH3_k127_1165858_3	1121405.dsmv_0517	1.717e-37	149.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,2MJ99@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
WLSH3_k127_1165858_1	635013.TherJR_0217	6.925e-97	326.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,2608D@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
WLSH3_k127_1165858_4	666509.RCA23_c10910	6.359e-24	116.0	COG0457@1|root,COG4122@1|root,COG0457@2|Bacteria,COG4122@2|Bacteria,1MVMG@1224|Proteobacteria,2TSGE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_1,TPR_11,TPR_12,TPR_16,TPR_2,TPR_6,TPR_8
WLSH3_k127_1165858_2	880072.Desac_1033	8.839e-91	316.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2X1XQ@28221|Deltaproteobacteria,2MRAF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH3_k127_1165858_0	671143.DAMO_0005	1.039e-120	402.0	COG0612@1|root,COG0612@2|Bacteria,2NP50@2323|unclassified Bacteria	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WLSH3_k127_1165858_5	1500894.JQNN01000001_gene723	0.0001025	46.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
WLSH3_k127_1183887_2	888816.HMPREF9389_0913	3.597e-07	53.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,4HBV3@91061|Bacilli,1WQCP@1305|Streptococcus sanguinis	91061|Bacilli	F	cog cog0402	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WLSH3_k127_1183887_1	1499684.CCNP01000025_gene3699	2.008e-57	206.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,36H4D@31979|Clostridiaceae	186801|Clostridia	G	Class II aldolase	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
WLSH3_k127_1183887_0	555079.Toce_1646	4.494e-143	464.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42F65@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
WLSH3_k127_1203029_11	298653.Franean1_4351	2.526e-19	94.0	COG0664@1|root,COG1225@1|root,COG1994@1|root,COG0664@2|Bacteria,COG1225@2|Bacteria,COG1994@2|Bacteria,2IBWH@201174|Actinobacteria	201174|Actinobacteria	O	Peptidase M50	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	AhpC-TSA,FHA,Yop-YscD_cpl,cNMP_binding
WLSH3_k127_1203029_5	1379698.RBG1_1C00001G0870	7.688e-48	178.0	COG1057@1|root,COG1057@2|Bacteria,2NPJU@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	iAF987.Gmet_3200	CTP_transf_like,HD
WLSH3_k127_1203029_7	518766.Rmar_0679	2.455e-30	128.0	COG4105@1|root,COG4105@2|Bacteria,4NJ5A@976|Bacteroidetes,1FITY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Outer membrane lipoprotein	yfiO	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
WLSH3_k127_1203029_0	1379698.RBG1_1C00001G1654	7.514e-235	736.0	COG0606@1|root,COG0606@2|Bacteria,2NNW7@2323|unclassified Bacteria	2|Bacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WLSH3_k127_1203029_2	243231.GSU2509	2.314e-99	329.0	COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,43UY4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
WLSH3_k127_1203029_10	56780.SYN_00772	9.378e-22	100.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria,2MQQY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
WLSH3_k127_1203029_4	485916.Dtox_1204	1.385e-60	215.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,261GI@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WLSH3_k127_1203029_6	68170.KL590503_gene220	2.37e-39	150.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4E3E1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WLSH3_k127_1203029_3	2325.TKV_c13740	9.674e-83	281.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,42ET2@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WLSH3_k127_1203029_9	562970.Btus_1453	8.291e-22	102.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,279UK@186823|Alicyclobacillaceae	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WLSH3_k127_1203029_8	335543.Sfum_2998	4.936e-24	102.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,2MQIW@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
WLSH3_k127_1203029_12	429009.Adeg_1416	3.776e-12	72.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,42GTF@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WLSH3_k127_1203029_1	880073.Calab_2050	2.444e-152	494.0	COG0541@1|root,COG0541@2|Bacteria,2NNT9@2323|unclassified Bacteria	2|Bacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WLSH3_k127_1223331_2	1504822.CCNO01000011_gene174	0.0005206	47.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009977,GO:0009987,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117,ko:K03425	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WLSH3_k127_1223331_1	667014.Thein_2133	1.374e-11	76.0	COG1450@1|root,COG1450@2|Bacteria,2GI8Z@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Bacterial type II/III secretion system short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
WLSH3_k127_1223331_0	1303518.CCALI_00923	4.496e-214	674.0	COG0495@1|root,COG0495@2|Bacteria	2|Bacteria	J	leucyl-tRNA aminoacylation	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WLSH3_k127_1331425_0	309799.DICTH_1785	3.211e-171	556.0	COG0068@1|root,COG0068@2|Bacteria	2|Bacteria	O	protein carbamoylation	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
WLSH3_k127_1331425_1	7460.GB51381-PA	3.44e-05	56.0	KOG4674@1|root,KOG4674@2759|Eukaryota,3ABTF@33154|Opisthokonta,3BVF7@33208|Metazoa,3E63H@33213|Bilateria,42B5Y@6656|Arthropoda,3T0K2@50557|Insecta,46KAA@7399|Hymenoptera	33208|Metazoa	S	spindle assembly checkpoint	-	-	-	ko:K20478	-	-	-	-	ko00000,ko04131	-	-	-	-
WLSH3_k127_1358163_1	760192.Halhy_1261	1.759e-13	73.0	COG1956@1|root,COG1956@2|Bacteria,4NM6D@976|Bacteroidetes,1ISIR@117747|Sphingobacteriia	976|Bacteroidetes	T	GAF domain	msrC	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
WLSH3_k127_1358163_0	290397.Adeh_2849	2.803e-58	213.0	COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,42MGR@68525|delta/epsilon subdivisions,2X5KV@28221|Deltaproteobacteria,2YY40@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH3_k127_1358163_2	795359.TOPB45_0857	1.261e-05	54.0	COG0744@1|root,COG0744@2|Bacteria,2GHUC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Transglycosylase	-	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
WLSH3_k127_1378304_0	1125863.JAFN01000001_gene837	3.043e-51	186.0	COG2768@1|root,COG2768@2|Bacteria,1MXMK@1224|Proteobacteria,42M2Z@68525|delta/epsilon subdivisions,2WIN6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_4,Fer4_6,Fer4_7
WLSH3_k127_1378304_1	1540257.JQMW01000009_gene3812	5.148e-42	160.0	COG0454@1|root,COG0456@2|Bacteria,1VIBT@1239|Firmicutes,24B6J@186801|Clostridia,36F23@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH3_k127_1378304_2	272134.KB731326_gene40	6.889e-30	129.0	COG0457@1|root,COG0457@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
WLSH3_k127_1382624_2	1410613.JNKF01000016_gene2323	9.667e-06	55.0	COG1452@1|root,COG1452@2|Bacteria,4NDU3@976|Bacteroidetes,2FNPJ@200643|Bacteroidia	976|Bacteroidetes	M	OstA-like protein	lptD	-	-	-	-	-	-	-	-	-	-	-	OstA_2
WLSH3_k127_1382624_1	679935.Alfi_2385	1.165e-06	57.0	COG5373@1|root,COG5373@2|Bacteria,4PMZ8@976|Bacteroidetes,2G0MC@200643|Bacteroidia,22UJ0@171550|Rikenellaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
WLSH3_k127_1382624_0	1379698.RBG1_1C00001G0547	5.179e-55	203.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
WLSH3_k127_1392037_0	869210.Marky_1600	8.424e-67	231.0	COG1155@1|root,COG1155@2|Bacteria,1WI10@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	atpA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
WLSH3_k127_1403901_0	1379698.RBG1_1C00001G0397	1.236e-189	602.0	COG0773@1|root,COG0773@2|Bacteria,2NNPU@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the MurCDEF family	murC	GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iECP_1309.ECP_0093,iJN678.murC	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH3_k127_1403901_2	546271.Selsp_1156	1.036e-66	237.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4H20N@909932|Negativicutes	909932|Negativicutes	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WLSH3_k127_1403901_3	335543.Sfum_3472	7.241e-07	60.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,2MSFJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Essential cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
WLSH3_k127_1403901_1	1379281.AVAG01000035_gene1761	3.535e-142	460.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2M85X@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WLSH3_k127_1408110_0	56780.SYN_00242	8.272e-110	363.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MR9D@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
WLSH3_k127_1408110_1	518766.Rmar_1781	7.72e-107	359.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes	976|Bacteroidetes	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH3_k127_1408110_2	518766.Rmar_1782	1.341e-104	351.0	COG0842@1|root,COG0842@2|Bacteria,4NDU0@976|Bacteroidetes	976|Bacteroidetes	V	transport, permease protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WLSH3_k127_1408110_5	65071.PYU1_T005551	2.539e-07	60.0	COG3914@1|root,KOG4626@2759|Eukaryota,1MB8T@121069|Pythiales	121069|Pythiales	GOT	Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1408110_3	1379698.RBG1_1C00001G0502	6.819e-44	169.0	COG1729@1|root,COG1729@2|Bacteria,2NQ0B@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
WLSH3_k127_1408110_4	1499967.BAYZ01000028_gene1349	1.519e-28	116.0	COG2885@1|root,COG2885@2|Bacteria,2NPMV@2323|unclassified Bacteria	2|Bacteria	M	OmpA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
WLSH3_k127_141707_3	398767.Glov_0556	1.147e-32	130.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2WPG2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WLSH3_k127_141707_2	398720.MED217_00935	3.049e-41	156.0	COG0782@1|root,COG0782@2|Bacteria,4NNH6@976|Bacteroidetes,1I18I@117743|Flavobacteriia,2XIK9@283735|Leeuwenhoekiella	976|Bacteroidetes	K	Transcription elongation factor, N-terminal	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WLSH3_k127_141707_0	502025.Hoch_3647	2.19e-166	529.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
WLSH3_k127_141707_1	1121957.ATVL01000009_gene1167	1.359e-103	351.0	COG0025@1|root,COG0025@2|Bacteria,4NK07@976|Bacteroidetes,47NVA@768503|Cytophagia	976|Bacteroidetes	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WLSH3_k127_141707_4	1121937.AUHJ01000013_gene843	9.916e-14	79.0	COG1566@1|root,COG1566@2|Bacteria,1RJ3I@1224|Proteobacteria,1S7BS@1236|Gammaproteobacteria,46ACD@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
WLSH3_k127_1444627_0	768704.Desmer_3528	9.431e-63	239.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1V0H0@1239|Firmicutes,25C7Q@186801|Clostridia,263NU@186807|Peptococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP pyruvate binding	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WLSH3_k127_1444627_1	70601.3256478	1.488e-41	157.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,242QQ@183968|Thermococci	183968|Thermococci	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH3_k127_1457455_1	1209989.TepiRe1_1178	9.008e-59	210.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,42GE6@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
WLSH3_k127_1457455_0	926561.KB900617_gene1659	1.198e-59	229.0	COG4206@1|root,COG4206@2|Bacteria,1V287@1239|Firmicutes,24SUD@186801|Clostridia,3WB9E@53433|Halanaerobiales	186801|Clostridia	H	TonB-dependent Receptor Plug	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
WLSH3_k127_1493625_0	1047013.AQSP01000094_gene20	5.293e-179	574.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2NNXZ@2323|unclassified Bacteria	2|Bacteria	E	Formiminotransferase-cyclodeaminase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
WLSH3_k127_1493625_5	502025.Hoch_0258	3.42e-06	54.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
WLSH3_k127_1493625_4	379066.GAU_1933	2.078e-16	91.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WLSH3_k127_1493625_1	404589.Anae109_0697	7.213e-68	241.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42MM0@68525|delta/epsilon subdivisions,2WKXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
WLSH3_k127_1493625_3	502025.Hoch_0258	7.219e-20	105.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
WLSH3_k127_1493625_2	1379270.AUXF01000006_gene26	5.991e-37	160.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WLSH3_k127_158292_3	1121472.AQWN01000011_gene1256	7.922e-42	158.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,2601N@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WLSH3_k127_158292_2	477974.Daud_1959	5.722e-89	301.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,2604V@186807|Peptococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH3_k127_158292_0	1254432.SCE1572_36880	4.035e-102	353.0	COG0573@1|root,COG0581@1|root,COG0573@2|Bacteria,COG0581@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2Z0WI@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH3_k127_158292_1	246194.CHY_2116	9.04e-102	337.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,42F1M@68295|Thermoanaerobacterales	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WLSH3_k127_158292_4	1042156.CXIVA_13970	1.519e-15	77.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,36DJ4@31979|Clostridiaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WLSH3_k127_1633057_2	604354.TSIB_1244	2.125e-15	83.0	COG0641@1|root,arCOG00945@2157|Archaea,2XY9D@28890|Euryarchaeota,243DY@183968|Thermococci	183968|Thermococci	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
WLSH3_k127_1633057_1	1125863.JAFN01000001_gene1608	1.995e-41	163.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
WLSH3_k127_1633057_0	240015.ACP_0863	4.508e-216	693.0	COG2183@1|root,COG2183@2|Bacteria,3Y2QM@57723|Acidobacteria,2JIB9@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA binding	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
WLSH3_k127_1647360_0	903818.KI912268_gene3321	5.189e-112	367.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WLSH3_k127_1647360_2	497964.CfE428DRAFT_4431	9.74e-08	64.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
WLSH3_k127_1647360_3	518766.Rmar_0831	0.0002395	53.0	COG3419@1|root,COG3419@2|Bacteria	2|Bacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
WLSH3_k127_1647360_1	1408254.T458_01430	6.99e-38	145.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,26T31@186822|Paenibacillaceae	91061|Bacilli	J	asparaginyl-tRNA synthetase	asnS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WLSH3_k127_1667362_0	720554.Clocl_2468	9.078e-247	776.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3WGEU@541000|Ruminococcaceae	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
WLSH3_k127_1667362_1	2055.JNXA01000003_gene4521	4.65e-31	128.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4GAT1@85026|Gordoniaceae	201174|Actinobacteria	U	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WLSH3_k127_1672670_1	1117647.M5M_09350	1.648e-09	70.0	COG0457@1|root,COG3118@1|root,COG0457@2|Bacteria,COG3118@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1J5FN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
WLSH3_k127_1672670_0	246197.MXAN_2703	3.417e-60	216.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria,2YWV3@29|Myxococcales	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
WLSH3_k127_1683890_1	96561.Dole_2168	2.622e-23	102.0	COG0778@1|root,COG0778@2|Bacteria,1MWMJ@1224|Proteobacteria,42R9J@68525|delta/epsilon subdivisions,2WN13@28221|Deltaproteobacteria,2MJNG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_1683890_0	224325.AF_1263	5.159e-47	183.0	COG1145@1|root,arCOG02189@2157|Archaea,2Y4FX@28890|Euryarchaeota	28890|Euryarchaeota	C	ferredoxin iron-sulfur binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH3_k127_1713051_6	338963.Pcar_3143	3.333e-07	59.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,43UAU@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WLSH3_k127_1713051_1	1174528.JH992898_gene4863	5.847e-22	97.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,1JJ19@1189|Stigonemataceae	1117|Cyanobacteria	S	Haemolytic	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WLSH3_k127_1713051_4	1304880.JAGB01000005_gene2441	4.155e-09	62.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WLSH3_k127_1713051_2	643867.Ftrac_1678	1.05e-15	77.0	COG0230@1|root,COG0230@2|Bacteria,4NUTV@976|Bacteroidetes,47RUZ@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
WLSH3_k127_1713051_0	882.DVU_2113	9.178e-126	416.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,42MAE@68525|delta/epsilon subdivisions,2WKFF@28221|Deltaproteobacteria,2M7ZE@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Permease family	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
WLSH3_k127_1713051_5	868131.MSWAN_2207	1.499e-08	61.0	arCOG10450@1|root,arCOG10450@2157|Archaea,2Y5CF@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1713051_3	526222.Desal_2286	1.132e-12	72.0	2CA4Y@1|root,2ZEN4@2|Bacteria,1P53E@1224|Proteobacteria,432N0@68525|delta/epsilon subdivisions,2WXSD@28221|Deltaproteobacteria,2MB69@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1717979_5	550540.Fbal_2211	4.337e-05	46.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WLSH3_k127_1717979_1	338963.Pcar_1282	4.654e-51	186.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
WLSH3_k127_1717979_0	1304275.C41B8_14445	2.071e-51	189.0	COG0558@1|root,COG0558@2|Bacteria,1P1W5@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WLSH3_k127_1717979_2	1033802.SSPSH_002496	4.292e-42	168.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4,Sterile
WLSH3_k127_1717979_3	326427.Cagg_2773	2.164e-19	89.0	28VCT@1|root,2ZHFH@2|Bacteria,2GB88@200795|Chloroflexi,377J8@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1717979_4	479432.Sros_5104	6.037e-08	64.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria,4EPVC@85012|Streptosporangiales	201174|Actinobacteria	M	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Cytochrom_D1,Lactonase
WLSH3_k127_179841_1	1365176.N186_09075	2.689e-15	76.0	COG1131@1|root,arCOG00196@2157|Archaea	2157|Archaea	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_179841_0	96561.Dole_0148	2.562e-65	241.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WLSH3_k127_1831199_3	509191.AEDB02000084_gene5186	2.119e-13	72.0	COG1073@1|root,COG1073@2|Bacteria,1V7R5@1239|Firmicutes,25D2R@186801|Clostridia,3WMD1@541000|Ruminococcaceae	186801|Clostridia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1831199_1	452637.Oter_1485	2.11e-35	140.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	aac	GO:0003674,GO:0003824,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034069,GO:0042221,GO:0046677,GO:0047663,GO:0050896	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WLSH3_k127_1831199_0	2325.TKV_c01400	1.665e-75	257.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,42G9C@68295|Thermoanaerobacterales	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH3_k127_1831199_2	1236689.MMALV_12140	1.088e-21	99.0	COG0574@1|root,arCOG01111@2157|Archaea,2XU2T@28890|Euryarchaeota,3F2MC@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH3_k127_186609_0	1379698.RBG1_1C00001G1846	2.144e-106	366.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WLSH3_k127_186609_1	986075.CathTA2_0959	1.132e-97	325.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli	91061|Bacilli	O	Belongs to the ClpA ClpB family	clpC	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WLSH3_k127_1867508_3	926550.CLDAP_05560	8.588e-20	92.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
WLSH3_k127_1867508_2	1499967.BAYZ01000104_gene3644	1.708e-41	158.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	DUF3795,OsmC
WLSH3_k127_1867508_1	521098.Aaci_2000	2.917e-114	374.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,2788E@186823|Alicyclobacillaceae	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WLSH3_k127_1867508_0	1519464.HY22_07070	7.174e-141	452.0	COG0481@1|root,COG0481@2|Bacteria,1FDSU@1090|Chlorobi	1090|Chlorobi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WLSH3_k127_1879335_4	880073.Calab_0942	2.349e-47	176.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WLSH3_k127_1879335_0	572547.Amico_1584	2.43e-127	430.0	COG1249@1|root,COG1249@2|Bacteria,3TA32@508458|Synergistetes	508458|Synergistetes	C	Dihydrolipoyl dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
WLSH3_k127_1879335_2	1217720.ALOX01000044_gene976	8.832e-61	228.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TQQH@28211|Alphaproteobacteria,2JPU2@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC transporter, substrate-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH3_k127_1879335_1	1123326.JFBL01000005_gene1136	9.346e-80	287.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42N16@68525|delta/epsilon subdivisions,2YS49@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	COG0747 ABC-type dipeptide transport system, periplasmic component	dppA	-	-	ko:K02035,ko:K12368	ko02010,ko02024,ko02030,map02010,map02024,map02030	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WLSH3_k127_1879335_3	523845.AQXV01000053_gene681	3.263e-60	227.0	COG0840@1|root,arCOG02320@2157|Archaea,2Y7QV@28890|Euryarchaeota,23RVM@183939|Methanococci	183939|Methanococci	T	Integral membrane sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
WLSH3_k127_1879335_5	1121396.KB893063_gene1188	2.003e-27	115.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MJ7C@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_1893504_1	945713.IALB_1264	5.22e-43	165.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	kdtX	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
WLSH3_k127_1893504_0	1123371.ATXH01000022_gene968	1.475e-44	168.0	COG0241@1|root,COG0241@2|Bacteria,2GHMG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
WLSH3_k127_1893504_2	880073.Calab_1374	6.533e-39	158.0	COG2067@1|root,COG2067@2|Bacteria,2NQZT@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1893504_3	1519464.HY22_02800	2.52e-11	67.0	COG1572@1|root,COG1572@2|Bacteria,1FEX1@1090|Chlorobi	1090|Chlorobi	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
WLSH3_k127_1896751_3	1121422.AUMW01000019_gene1791	3.167e-99	327.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH3_k127_1896751_0	370438.PTH_2737	7.849e-299	932.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WLSH3_k127_1896751_4	861299.J421_4474	3.446e-50	201.0	2FK3F@1|root,34BRJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_1896751_2	697281.Mahau_1317	1.605e-169	540.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,42FF9@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WLSH3_k127_1896751_5	2325.TKV_c13850	8.659e-44	168.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,42FUI@68295|Thermoanaerobacterales	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WLSH3_k127_1896751_1	997346.HMPREF9374_0894	4.782e-178	567.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WLSH3_k127_1896751_6	696369.KI912183_gene876	6.556e-26	108.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,262SV@186807|Peptococcaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WLSH3_k127_1896751_7	380749.HY04AAS1_0509	8.635e-14	71.0	COG1028@1|root,COG1028@2|Bacteria,2G3IV@200783|Aquificae	200783|Aquificae	IQ	Short-chain dehydrogenase reductase SDR	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WLSH3_k127_1959340_1	945713.IALB_2034	1.828e-32	130.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
WLSH3_k127_1959340_0	671143.DAMO_1398	1.392e-100	339.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	livK	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iECNA114_1301.ECNA114_3569,iECSF_1327.ECSF_3279,iECs_1301.ECs4309,iEcSMS35_1347.EcSMS35_3743,iG2583_1286.G2583_4163,iSFxv_1172.SFxv_3794,iSSON_1240.SSON_3698,iS_1188.S4285,iUTI89_1310.UTI89_C3965,iYL1228.KPN_03820,iZ_1308.Z4834	Peripla_BP_6
WLSH3_k127_1996646_5	700015.Corgl_0847	2.436e-09	59.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4CW47@84998|Coriobacteriia	84998|Coriobacteriia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
WLSH3_k127_1996646_0	635013.TherJR_0131	3.345e-74	259.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia,2609P@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
WLSH3_k127_1996646_4	1191523.MROS_2301	4.053e-13	75.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WLSH3_k127_1996646_2	517418.Ctha_0064	1.407e-27	118.0	COG0799@1|root,COG0799@2|Bacteria,1FE3F@1090|Chlorobi	1090|Chlorobi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WLSH3_k127_1996646_1	443598.AUFA01000021_gene3018	1.251e-28	117.0	COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,3K0KJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH3_k127_1996646_3	386043.lwe2511	4.713e-22	100.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,26IVV@186820|Listeriaceae	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WLSH3_k127_2037742_1	883126.HMPREF9710_04337	1.669e-08	67.0	COG2203@1|root,COG3292@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VMUZ@28216|Betaproteobacteria,475JP@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Reg_prop,Y_Y_Y
WLSH3_k127_2037742_0	246197.MXAN_6420	2.657e-26	115.0	COG0515@1|root,COG2114@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,1QA6R@1224|Proteobacteria,438YW@68525|delta/epsilon subdivisions,2X449@28221|Deltaproteobacteria,2YY7T@29|Myxococcales	28221|Deltaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	pkn2	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Guanylate_cyc,Pkinase
WLSH3_k127_207201_0	1313304.CALK_1933	3.294e-56	217.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,HDOD,PAS_3,PAS_4,PilJ
WLSH3_k127_2101164_1	1191523.MROS_2499	3.667e-72	259.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_4
WLSH3_k127_2101164_0	1519464.HY22_12340	1.047e-133	437.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1FEI3@1090|Chlorobi	1090|Chlorobi	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
WLSH3_k127_2107540_0	1123376.AUIU01000012_gene1453	4.795e-147	477.0	COG0445@1|root,COG0445@2|Bacteria,3J0E9@40117|Nitrospirae	40117|Nitrospirae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
WLSH3_k127_2107540_1	1198114.AciX9_3733	3.082e-41	154.0	COG0445@1|root,COG0445@2|Bacteria,3Y3E4@57723|Acidobacteria,2JHP3@204432|Acidobacteriia	204432|Acidobacteriia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
WLSH3_k127_2108202_1	864702.OsccyDRAFT_3032	7.42e-31	138.0	COG0457@1|root,COG1293@1|root,COG4995@1|root,COG0457@2|Bacteria,COG1293@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
WLSH3_k127_2108202_0	289376.THEYE_A0140	4.369e-50	187.0	COG0744@1|root,COG0744@2|Bacteria,3J127@40117|Nitrospirae	40117|Nitrospirae	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
WLSH3_k127_2108202_2	290397.Adeh_2849	5.017e-05	54.0	COG0697@1|root,COG0697@2|Bacteria,1PX5W@1224|Proteobacteria,42MGR@68525|delta/epsilon subdivisions,2X5KV@28221|Deltaproteobacteria,2YY40@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH3_k127_2146857_3	1123008.KB905693_gene1422	2.662e-12	68.0	arCOG05093@1|root,339N6@2|Bacteria,4NYIM@976|Bacteroidetes,2FVF5@200643|Bacteroidia,22YYW@171551|Porphyromonadaceae	976|Bacteroidetes	S	Winged helix-turn-helix domain (DUF2582)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2582
WLSH3_k127_2146857_0	580327.Tthe_2264	4.8e-63	227.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,42FXA@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WLSH3_k127_2146857_1	1343739.PAP_03970	6.73e-53	198.0	COG0609@1|root,arCOG01007@2157|Archaea,2XT1A@28890|Euryarchaeota,2437B@183968|Thermococci	183968|Thermococci	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WLSH3_k127_2146857_2	765420.OSCT_1501	1.815e-44	173.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi,3763Q@32061|Chloroflexia	32061|Chloroflexia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WLSH3_k127_2163211_0	1385935.N836_26775	1.396e-74	270.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H7GW@1150|Oscillatoriales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
WLSH3_k127_2163211_1	909663.KI867150_gene548	4.17e-45	185.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2MQA8@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WLSH3_k127_2182023_1	1379698.RBG1_1C00001G1368	2.961e-44	177.0	COG4219@1|root,COG4219@2|Bacteria,2NS3V@2323|unclassified Bacteria	2|Bacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_6,DUF4309,DUF5301
WLSH3_k127_2182023_0	1111069.TCCBUS3UF1_14820	9.341e-51	186.0	COG1394@1|root,COG1394@2|Bacteria,1WJXJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WLSH3_k127_2182023_2	1120953.AUBH01000004_gene3177	2.132e-28	125.0	2F51T@1|root,33XPB@2|Bacteria,1NX1R@1224|Proteobacteria,1SNZB@1236|Gammaproteobacteria,46AX9@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2235359_1	518766.Rmar_0907	2.4e-45	167.0	COG1993@1|root,COG1993@2|Bacteria,4NX2K@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
WLSH3_k127_2235359_2	518766.Rmar_0908	7.842e-27	113.0	COG0239@1|root,COG0239@2|Bacteria,4PET1@976|Bacteroidetes,1FJJQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
WLSH3_k127_2235359_3	511051.CSE_09940	5.3e-25	119.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	resA	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin_8
WLSH3_k127_2235359_0	632518.Calow_0035	7.531e-238	746.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42F21@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
WLSH3_k127_2291585_1	485913.Krac_11684	1.98e-35	142.0	COG1216@1|root,COG1216@2|Bacteria,2G69V@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WLSH3_k127_2291585_0	1379698.RBG1_1C00001G0995	1.394e-160	531.0	COG5617@1|root,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria	2|Bacteria	E	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WLSH3_k127_2299019_3	880073.Calab_3240	7.794e-50	180.0	COG0509@1|root,COG0509@2|Bacteria,2NPMR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WLSH3_k127_2299019_0	696281.Desru_3281	2.554e-151	490.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,2608E@186807|Peptococcaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WLSH3_k127_2299019_2	656519.Halsa_0394	5.773e-65	235.0	COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,247M7@186801|Clostridia,3WAE2@53433|Halanaerobiales	186801|Clostridia	M	PFAM Glycosyl transferase family 4	tagO	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
WLSH3_k127_2299019_1	1230342.CTM_23247	5.081e-81	280.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,36E02@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
WLSH3_k127_2299019_4	1408813.AYMG01000001_gene3571	0.0009656	49.0	COG1266@1|root,COG1266@2|Bacteria,4NHE1@976|Bacteroidetes,1ITS1@117747|Sphingobacteriia	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WLSH3_k127_2299280_0	1232410.KI421412_gene97	9.453e-131	437.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,43SAQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma-70 factor, region 1.1	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH3_k127_2299280_1	880073.Calab_3104	2.33e-61	224.0	COG2356@1|root,COG4447@1|root,COG2356@2|Bacteria,COG4447@2|Bacteria,2NRJS@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease I	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Endonuclease_1,FlgD_ig,LTD,PSII_BNR
WLSH3_k127_2324810_0	661478.OP10G_0051	9.578e-113	374.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH3_k127_2324810_1	273068.TTE1263	7.643e-111	368.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH3_k127_2324810_2	1123388.AQWU01000073_gene1087	1.515e-13	79.0	COG0641@1|root,COG0641@2|Bacteria,1WJKB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
WLSH3_k127_2344452_2	1379698.RBG1_1C00001G1860	5.975e-61	213.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WLSH3_k127_2344452_4	1379698.RBG1_1C00001G1001	8.45e-29	127.0	COG1792@1|root,COG1792@2|Bacteria,2NPNX@2323|unclassified Bacteria	2|Bacteria	M	Cell shape-determining protein MreC	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WLSH3_k127_2344452_5	1121472.AQWN01000006_gene1698	9.617e-10	66.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24RP5@186801|Clostridia,262R9@186807|Peptococcaceae	186801|Clostridia	M	shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
WLSH3_k127_2344452_0	1379698.RBG1_1C00001G1003	4.963e-135	451.0	COG0768@1|root,COG0768@2|Bacteria,2NNYI@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding protein 2	mrdA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928,iEcE24377_1341.EcE24377A_0661,iPC815.YPO2604	PBP_dimer,Transpeptidase
WLSH3_k127_2344452_1	1379698.RBG1_1C00001G1004	8.14e-91	315.0	COG0772@1|root,COG0772@2|Bacteria,2NNRP@2323|unclassified Bacteria	2|Bacteria	D	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WLSH3_k127_2344452_3	515635.Dtur_0951	2.692e-43	162.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WLSH3_k127_238788_2	1196323.ALKF01000188_gene4826	6.544e-09	69.0	COG1404@1|root,COG3408@1|root,COG4412@1|root,COG1404@2|Bacteria,COG3408@2|Bacteria,COG4412@2|Bacteria,1TPUY@1239|Firmicutes,4HBDE@91061|Bacilli,26QNY@186822|Paenibacillaceae	91061|Bacilli	O	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Peptidase_M6,Peptidase_S8,SLH
WLSH3_k127_238788_1	1379698.RBG1_1C00001G1738	2.284e-21	99.0	COG1596@1|root,COG1596@2|Bacteria,2NPYH@2323|unclassified Bacteria	2|Bacteria	M	SLBB domain	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
WLSH3_k127_238788_0	1304880.JAGB01000005_gene2427	3.589e-176	558.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WLSH3_k127_2422760_2	1511.CLOST_2295	1.127e-86	289.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,25QUC@186804|Peptostreptococcaceae	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	hymB	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
WLSH3_k127_2422760_0	555079.Toce_0243	1.222e-274	884.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10,1.17.1.9,1.97.1.9	ko:K00123,ko:K12527,ko:K15022	ko00450,ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00450,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519,R07229	RC02420,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Pyr_redox_2,Pyr_redox_3
WLSH3_k127_2422760_7	1121930.AQXG01000001_gene1165	0.000552	53.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Laminin_G_3
WLSH3_k127_2422760_6	1122223.KB890699_gene613	7.18e-10	72.0	COG3055@1|root,COG3055@2|Bacteria,1WK3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
WLSH3_k127_2422760_5	13035.Dacsa_3406	2.118e-46	174.0	COG1047@1|root,COG1047@2|Bacteria,1G5R4@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
WLSH3_k127_2422760_3	32057.KB217480_gene7997	1.519e-73	264.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	SLH,WG_beta_rep
WLSH3_k127_2422760_4	1321778.HMPREF1982_02729	3.06e-67	234.0	COG0778@1|root,COG0778@2|Bacteria,1V4ZI@1239|Firmicutes,24BD0@186801|Clostridia	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_2422760_1	1279009.ADICEAN_02558	2.553e-128	423.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
WLSH3_k127_2426852_1	459349.CLOAM0583	1.703e-15	84.0	COG1404@1|root,COG1470@1|root,COG1404@2|Bacteria,COG1470@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Calx-beta,CarboxypepD_reg,DUF11,FlgD_ig,HYR,PKD,PPC,SLH,VCBS,fn3
WLSH3_k127_2426852_0	1341155.FSS13T_20250	8.395e-47	186.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HWSK@117743|Flavobacteriia,2NUEG@237|Flavobacterium	976|Bacteroidetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4
WLSH3_k127_2433410_2	439481.Aboo_0437	2.195e-35	139.0	COG0622@1|root,arCOG01141@2157|Archaea,2XX8V@28890|Euryarchaeota,3F3B8@33867|unclassified Euryarchaeota	28890|Euryarchaeota	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
WLSH3_k127_2433410_0	525904.Tter_1708	2.111e-73	256.0	COG1606@1|root,COG1606@2|Bacteria,2NP5T@2323|unclassified Bacteria	2|Bacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
WLSH3_k127_2433410_3	273068.TTE0770	4.824e-18	86.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,42FCC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
WLSH3_k127_2433410_1	1094508.Tsac_1492	2.684e-52	188.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,42FCC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
WLSH3_k127_2489509_3	1379698.RBG1_1C00001G1174	6.663e-35	136.0	COG1611@1|root,COG1611@2|Bacteria,2NPJB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A,Lysine_decarbox
WLSH3_k127_2489509_1	526222.Desal_1807	3.38e-75	258.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,2M7VK@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WLSH3_k127_2489509_0	710111.FraQA3DRAFT_5911	5.094e-111	372.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,4EXBW@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WLSH3_k127_2489509_2	635013.TherJR_1929	6.265e-68	239.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,260JN@186807|Peptococcaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WLSH3_k127_2521589_5	1046724.KB889827_gene2696	5.81e-13	78.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,465B1@72275|Alteromonadaceae	1236|Gammaproteobacteria	Q	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0010340,GO:0016053,GO:0016740,GO:0016741,GO:0016787,GO:0016788,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_0791,iSBO_1134.SBO_0664,iSFV_1184.SFV_0760,iSF_1195.SF0727,iSFxv_1172.SFxv_0792,iSSON_1240.SSON_0756,iS_1188.S0768,iSbBS512_1146.SbBS512_E2575	Methyltransf_11
WLSH3_k127_2521589_4	246197.MXAN_1151	3.854e-32	144.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WLSH3_k127_2521589_3	518766.Rmar_2254	4.17e-61	224.0	COG2812@1|root,COG2812@2|Bacteria,4PKEA@976|Bacteroidetes,1FJ1I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
WLSH3_k127_2521589_2	1121428.DESHY_40113___1	3.332e-70	246.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,260CA@186807|Peptococcaceae	186801|Clostridia	S	pfam psp1	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
WLSH3_k127_2521589_0	525904.Tter_0176	3.122e-183	603.0	COG0143@1|root,COG0143@2|Bacteria,2NNTX@2323|unclassified Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
WLSH3_k127_2521589_6	314275.MADE_1004255	2.796e-05	54.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,4645J@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degS	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
WLSH3_k127_2557193_0	661478.OP10G_0051	4.417e-78	278.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH3_k127_2557193_1	370438.PTH_1596	4.762e-61	227.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,261QQ@186807|Peptococcaceae	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD
WLSH3_k127_2557193_3	316274.Haur_4216	0.0002827	53.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
WLSH3_k127_2557193_2	1047013.AQSP01000140_gene2511	1.311e-05	57.0	COG2202@1|root,COG2203@1|root,COG3920@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3920@2|Bacteria,2NPS5@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.7.13.3	ko:K00936,ko:K02030	-	M00236,M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.3	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,PAS_3,PAS_9
WLSH3_k127_2575420_3	207559.Dde_2991	2.995e-22	98.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria,2M7ZI@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
WLSH3_k127_2575420_1	1499967.BAYZ01000113_gene2935	1.53e-59	209.0	COG0080@1|root,COG0080@2|Bacteria,2NP7W@2323|unclassified Bacteria	2|Bacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
WLSH3_k127_2575420_0	1379698.RBG1_1C00001G1608	1.096e-89	301.0	COG0081@1|root,COG0081@2|Bacteria,2NNK6@2323|unclassified Bacteria	2|Bacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WLSH3_k127_2575420_2	748449.Halha_0180	6.077e-48	177.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WANA@53433|Halanaerobiales	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WLSH3_k127_2575420_4	580340.Tlie_0449	1.318e-14	75.0	COG0222@1|root,COG0222@2|Bacteria,3TB80@508458|Synergistetes	508458|Synergistetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WLSH3_k127_2585451_2	679200.HMPREF9333_00676	1.158e-05	53.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia	186801|Clostridia	J	Elongation factor	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
WLSH3_k127_2585451_0	671143.DAMO_1099	2.504e-59	212.0	COG0704@1|root,COG1392@1|root,COG0704@2|Bacteria,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU,PhoU_div
WLSH3_k127_2585451_1	1122132.AQYH01000004_gene1644	1.131e-20	91.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,4B951@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WLSH3_k127_2593289_0	1379698.RBG1_1C00001G0961	7.984e-223	707.0	COG0550@1|root,COG0550@2|Bacteria,2NNS8@2323|unclassified Bacteria	2|Bacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WLSH3_k127_2593289_1	1449126.JQKL01000014_gene2985	9.749e-31	123.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,268B4@186813|unclassified Clostridiales	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
WLSH3_k127_2597175_2	1379698.RBG1_1C00001G1809	2.875e-33	133.0	COG1183@1|root,COG1183@2|Bacteria,2NPQM@2323|unclassified Bacteria	2|Bacteria	I	CDP-alcohol phosphatidyltransferase	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
WLSH3_k127_2597175_1	857293.CAAU_0708	4.248e-50	187.0	COG0688@1|root,COG0688@2|Bacteria,1V3FQ@1239|Firmicutes,24FXF@186801|Clostridia	186801|Clostridia	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
WLSH3_k127_2597175_3	497965.Cyan7822_4919	1.546e-22	111.0	COG2199@1|root,COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4191@2|Bacteria,1FZWU@1117|Cyanobacteria,3KH1Z@43988|Cyanothece	1117|Cyanobacteria	T	Diguanylate cyclase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,GGDEF,PAS_3,PAS_9
WLSH3_k127_2597175_0	1121468.AUBR01000026_gene2957	1.88e-167	536.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,42FJ7@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WLSH3_k127_2604174_1	290397.Adeh_1197	6.251e-16	88.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
WLSH3_k127_2604174_4	316274.Haur_3925	0.00013	51.0	COG2018@1|root,COG2018@2|Bacteria,2GB8V@200795|Chloroflexi,377K6@32061|Chloroflexia	32061|Chloroflexia	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
WLSH3_k127_2604174_2	209285.XP_006697292.1	1.204e-15	85.0	COG0484@1|root,KOG0550@2759|Eukaryota,38CD1@33154|Opisthokonta,3NV1Y@4751|Fungi,3QQ9D@4890|Ascomycota,211NY@147550|Sordariomycetes,3U5TH@5139|Sordariales	4751|Fungi	O	Tetratricopeptide repeat	-	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0030544,GO:0031072,GO:0051084,GO:0051085,GO:0061077	-	ko:K09527	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
WLSH3_k127_2604174_3	41431.PCC8801_3267	1.538e-11	75.0	COG0457@1|root,COG1216@1|root,COG3914@1|root,COG0457@2|Bacteria,COG1216@2|Bacteria,COG3914@2|Bacteria,1G0YS@1117|Cyanobacteria	1117|Cyanobacteria	O	O-linked N-acetylglucosamine transferase SPINDLY family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Sulfotransfer_2,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
WLSH3_k127_2604174_0	861299.J421_3338	3.623e-130	432.0	COG1530@1|root,COG1530@2|Bacteria,1ZSZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
WLSH3_k127_2605152_3	1170562.Cal6303_1983	3.578e-27	125.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HK1F@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
WLSH3_k127_2605152_1	290397.Adeh_3633	1.427e-88	295.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
WLSH3_k127_2605152_2	861299.J421_2885	3.533e-33	134.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
WLSH3_k127_2605152_0	574087.Acear_0037	9.557e-118	385.0	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,3WAIQ@53433|Halanaerobiales	186801|Clostridia	C	PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH3_k127_2616326_0	880072.Desac_0526	3.317e-54	195.0	2BC31@1|root,325MS@2|Bacteria,1NBYV@1224|Proteobacteria,431MW@68525|delta/epsilon subdivisions,2WWTC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2616326_3	639282.DEFDS_1866	2.589e-09	62.0	2EM0R@1|root,33EQ9@2|Bacteria,2GG28@200930|Deferribacteres	200930|Deferribacteres	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2616326_2	880072.Desac_2173	8.598e-44	167.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria,2MS0M@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WLSH3_k127_2616326_1	335543.Sfum_1996	1.003e-48	181.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
WLSH3_k127_2663055_0	1121957.ATVL01000009_gene1369	6.356e-122	412.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WLSH3_k127_2663055_2	497965.Cyan7822_0442	2.473e-61	221.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,3KGBC@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WLSH3_k127_2663055_1	1196322.A370_04658	1.755e-66	240.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,36EQY@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
WLSH3_k127_2689940_3	378806.STAUR_3906	0.0001924	49.0	COG3746@1|root,COG3746@2|Bacteria,1PBWD@1224|Proteobacteria,433TT@68525|delta/epsilon subdivisions,2X3F8@28221|Deltaproteobacteria,2YVU2@29|Myxococcales	28221|Deltaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2689940_0	290397.Adeh_4006	1.075e-103	344.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WLSH3_k127_2689940_1	290397.Adeh_4005	7.533e-91	308.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WLSH3_k127_2689940_2	290397.Adeh_4004	9.475e-06	49.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
WLSH3_k127_2732127_0	1047013.AQSP01000076_gene1478	2.044e-57	207.0	COG1600@1|root,COG1600@2|Bacteria,2NRKC@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_16,Fer4_7
WLSH3_k127_2732127_2	344747.PM8797T_23049	1.25e-29	130.0	2CBIH@1|root,33WXG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2732127_1	237368.SCABRO_02876	5.664e-30	124.0	2CA4A@1|root,32RQK@2|Bacteria,2J0BM@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4416)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4416
WLSH3_k127_2732839_7	926550.CLDAP_17040	1.093e-51	190.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WLSH3_k127_2732839_0	1379698.RBG1_1C00001G1497	1.836e-196	623.0	COG1003@1|root,COG1003@2|Bacteria,2NNSG@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS11880	Aminotran_5,GDC-P
WLSH3_k127_2732839_4	639282.DEFDS_1066	4.778e-82	278.0	COG0410@1|root,COG0410@2|Bacteria,2GEK0@200930|Deferribacteres	200930|Deferribacteres	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WLSH3_k127_2732839_9	1232410.KI421418_gene2109	5.839e-28	127.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,43SFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
WLSH3_k127_2732839_3	279714.FuraDRAFT_2486	7.573e-92	308.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,2KQG5@206351|Neisseriales	206351|Neisseriales	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WLSH3_k127_2732839_6	497964.CfE428DRAFT_5270	9.687e-68	235.0	COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
WLSH3_k127_2732839_1	671143.DAMO_1396	8.025e-113	375.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,2NNYG@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livM	GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iPC815.YPO3806,iSDY_1059.SDY_3605	ABC_tran,BCA_ABC_TP_C,BPD_transp_2,DUF3382
WLSH3_k127_2732839_2	671143.DAMO_1397	6.26e-105	349.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	iJN746.PP_4866,iSFV_1184.SFV_3460,iSF_1195.SF3475,iSFxv_1172.SFxv_3791,iS_1188.S4288	BPD_transp_2
WLSH3_k127_2732839_8	926550.CLDAP_39790	1e-35	138.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH3_k127_2804121_0	439481.Aboo_0238	1.944e-52	201.0	arCOG06939@1|root,arCOG06939@2157|Archaea,2XWTJ@28890|Euryarchaeota	28890|Euryarchaeota	S	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
WLSH3_k127_2804121_1	755732.Fluta_2190	2.109e-50	183.0	COG2120@1|root,COG2120@2|Bacteria,4NN16@976|Bacteroidetes	976|Bacteroidetes	S	PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WLSH3_k127_2804121_5	755732.Fluta_2190	1.137e-11	65.0	COG2120@1|root,COG2120@2|Bacteria,4NN16@976|Bacteroidetes	976|Bacteroidetes	S	PFAM N-acetylglucosaminyl phosphatidylinositol deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WLSH3_k127_2804121_2	1121904.ARBP01000007_gene3028	5.903e-15	87.0	COG0438@1|root,COG0438@2|Bacteria,4NG0D@976|Bacteroidetes,47KPB@768503|Cytophagia	976|Bacteroidetes	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WLSH3_k127_2804121_3	1333523.L593_14185	3.077e-13	81.0	COG0535@1|root,arCOG00940@2157|Archaea,2Y8D3@28890|Euryarchaeota,24190@183963|Halobacteria	183963|Halobacteria	S	Radical SAM domain protein	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
WLSH3_k127_2804121_4	1114970.PSF113_1959	5.8e-12	74.0	COG2244@1|root,COG2244@2|Bacteria,1QS7T@1224|Proteobacteria,1RU3F@1236|Gammaproteobacteria,1YNMJ@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
WLSH3_k127_2806750_5	926569.ANT_16840	2.734e-20	94.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WLSH3_k127_2806750_6	246969.TAM4_2167	6.846e-11	66.0	COG1145@1|root,arCOG00958@2157|Archaea,2Y1CC@28890|Euryarchaeota,244IB@183968|Thermococci	183968|Thermococci	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH3_k127_2806750_3	1379698.RBG1_1C00001G1891	1.762e-70	247.0	COG1646@1|root,COG1646@2|Bacteria,2NQW0@2323|unclassified Bacteria	2|Bacteria	I	PcrB family	pcrB	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576	-	ko:K07094	-	-	-	-	ko00000,ko01000	-	-	-	PcrB
WLSH3_k127_2806750_0	1379698.RBG1_1C00001G0168	4.582e-100	331.0	COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria	2|Bacteria	M	Nucleotidyl transferase	spsI	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WLSH3_k127_2806750_2	748449.Halha_2377	6.296e-91	306.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3WAQC@53433|Halanaerobiales	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WLSH3_k127_2806750_4	414684.RC1_0829	4.362e-47	176.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2U8QT@28211|Alphaproteobacteria,2JSGE@204441|Rhodospirillales	204441|Rhodospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WLSH3_k127_2806750_7	309801.trd_0687	1.22e-10	72.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi,27YNP@189775|Thermomicrobia	189775|Thermomicrobia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
WLSH3_k127_2806750_1	568816.Acin_0480	6.508e-92	312.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4H1XK@909932|Negativicutes	909932|Negativicutes	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WLSH3_k127_2821062_3	518766.Rmar_0355	9.286e-16	87.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WLSH3_k127_2821062_4	313628.LNTAR_23709	5.986e-08	62.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,CBM_2,CBM_4_9,Esterase_phd,Glyco_hydro_16,RicinB_lectin_2,SLH
WLSH3_k127_2821062_1	1499967.BAYZ01000159_gene477	1.162e-104	352.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
WLSH3_k127_2821062_0	945713.IALB_0639	1.195e-212	688.0	COG0532@1|root,COG0532@2|Bacteria	2|Bacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
WLSH3_k127_2821062_2	314231.FP2506_10481	4.417e-17	88.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,2PJ47@255475|Aurantimonadaceae	28211|Alphaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
WLSH3_k127_2832104_2	755732.Fluta_2847	1.218e-58	207.0	COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,1HWSP@117743|Flavobacteriia,2PA74@246874|Cryomorphaceae	976|Bacteroidetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WLSH3_k127_2832104_4	269799.Gmet_1165	2.395e-26	117.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WS27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
WLSH3_k127_2832104_3	56780.SYN_00106	4.258e-27	113.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2WRHX@28221|Deltaproteobacteria,2MQPT@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
WLSH3_k127_2832104_1	1379698.RBG1_1C00001G0100	4.432e-68	238.0	COG0325@1|root,COG0325@2|Bacteria,2NPEW@2323|unclassified Bacteria	2|Bacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WLSH3_k127_2832104_0	1379698.RBG1_1C00001G1562	6.547e-140	464.0	COG5009@1|root,COG5009@2|Bacteria,2NS4K@2323|unclassified Bacteria	2|Bacteria	M	Transglycosylase	mrcA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
WLSH3_k127_2841828_1	56780.SYN_02999	2.157e-33	132.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MRJM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WLSH3_k127_2841828_0	398767.Glov_0151	3.688e-56	201.0	COG3040@1|root,COG3040@2|Bacteria,1RIHP@1224|Proteobacteria,42SSW@68525|delta/epsilon subdivisions,2X6M9@28221|Deltaproteobacteria,43VBP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
WLSH3_k127_2841828_2	269797.Mbar_A0745	2.39e-27	120.0	arCOG10857@1|root,arCOG10857@2157|Archaea,2Y4UI@28890|Euryarchaeota	28890|Euryarchaeota	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
WLSH3_k127_2841828_3	929713.NIASO_14645	1.206e-22	98.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_2846565_0	1499967.BAYZ01000003_gene5878	1.217e-178	571.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WLSH3_k127_2848331_1	1521187.JPIM01000046_gene1476	2.483e-10	70.0	2DTMN@1|root,33KXV@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
WLSH3_k127_2848331_2	264462.Bd2642	4.73e-09	68.0	COG4254@1|root,COG4254@2|Bacteria,1NATC@1224|Proteobacteria,42X7Q@68525|delta/epsilon subdivisions,2MU59@213481|Bdellovibrionales,2WTAB@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WLSH3_k127_2848331_0	1121904.ARBP01000018_gene2642	3.617e-22	111.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,LTD
WLSH3_k127_2888274_0	1121920.AUAU01000014_gene2807	1.618e-29	124.0	COG0558@1|root,COG0558@2|Bacteria,3Y4S5@57723|Acidobacteria	57723|Acidobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WLSH3_k127_2888274_1	160799.PBOR_11835	2.698e-07	61.0	COG1361@1|root,COG4447@1|root,COG4625@1|root,COG1361@2|Bacteria,COG4447@2|Bacteria,COG4625@2|Bacteria,1VX9E@1239|Firmicutes,4HIIK@91061|Bacilli,26SBE@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Cohesin,DUF1573,SLH
WLSH3_k127_2903855_0	608506.COB47_0592	2.126e-110	365.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,42EXR@68295|Thermoanaerobacterales	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WLSH3_k127_2903855_3	688270.Celal_2222	2.335e-17	83.0	COG2827@1|root,COG2827@2|Bacteria,4NUN3@976|Bacteroidetes,1I51S@117743|Flavobacteriia,1FAHT@104264|Cellulophaga	976|Bacteroidetes	L	PFAM Excinuclease ABC, C subunit, N-terminal	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WLSH3_k127_2903855_1	760142.Hipma_1113	1.572e-25	109.0	COG2088@1|root,COG2088@2|Bacteria,1N14Y@1224|Proteobacteria,42TGF@68525|delta/epsilon subdivisions,2WQYK@28221|Deltaproteobacteria,2M7C1@213113|Desulfurellales	28221|Deltaproteobacteria	M	SpoVG	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
WLSH3_k127_2903855_2	1195236.CTER_1016	1.46e-22	103.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3WQ5Z@541000|Ruminococcaceae	186801|Clostridia	I	GHMP kinases N terminal domain	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
WLSH3_k127_2924447_2	926569.ANT_22030	3.222e-06	49.0	COG3261@1|root,COG3261@2|Bacteria,2G8BA@200795|Chloroflexi	200795|Chloroflexi	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	-	ko:K14090	-	-	-	-	ko00000	-	-	-	Complex1_49kDa,NiFeSe_Hases
WLSH3_k127_2924447_0	338966.Ppro_3523	1.213e-88	304.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WLSH3_k127_2924447_1	338966.Ppro_0597	3.895e-22	109.0	COG1143@1|root,COG1143@2|Bacteria,1RK71@1224|Proteobacteria,42Y1X@68525|delta/epsilon subdivisions,2WQB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K14091	-	-	-	-	ko00000	-	-	-	ETF_QO,Fer4,Fer4_7
WLSH3_k127_2944871_3	511051.CSE_06680	1.618e-19	95.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gtf2	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_2944871_0	309798.COPRO5265_1552	1.031e-148	481.0	COG0438@1|root,COG0438@2|Bacteria,1TS4X@1239|Firmicutes,24BYU@186801|Clostridia,42F0Q@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyl transferases group 1	-	-	2.4.1.245	ko:K13057	ko00500,ko01100,map00500,map01100	-	R08946,R10525,R11306	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000	-	GT4	-	Glycos_transf_1
WLSH3_k127_2944871_2	378806.STAUR_1866	3.844e-43	173.0	COG0637@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1877@2|Bacteria,1PFIU@1224|Proteobacteria,437Y6@68525|delta/epsilon subdivisions,2X9QB@28221|Deltaproteobacteria,2Z020@29|Myxococcales	28221|Deltaproteobacteria	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WLSH3_k127_2944871_1	1322246.BN4_10791	2.719e-104	360.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42PJQ@68525|delta/epsilon subdivisions,2WKR4@28221|Deltaproteobacteria,2M7SH@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	iAF987.Gmet_3470	CBS,Voltage_CLC
WLSH3_k127_2944871_4	1202962.KB907150_gene1736	0.0006343	43.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,1RN9V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	UPF0313 protein	ygiQ	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
WLSH3_k127_2955851_3	1337936.IJ00_06470	1.543e-13	76.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HIJM@1161|Nostocales	1117|Cyanobacteria	S	SPTR Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
WLSH3_k127_2955851_0	243231.GSU1274	5.117e-103	344.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria,43SFJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WLSH3_k127_2955851_1	247490.KSU1_A0086	1.096e-76	277.0	COG0642@1|root,COG2205@2|Bacteria,2J4XW@203682|Planctomycetes	203682|Planctomycetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WLSH3_k127_2955851_2	316067.Geob_1006	4.242e-31	125.0	COG0784@1|root,COG0784@2|Bacteria,1N017@1224|Proteobacteria,42UW8@68525|delta/epsilon subdivisions,2X7PA@28221|Deltaproteobacteria,43W1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WLSH3_k127_2981736_0	82654.Pse7367_1123	1.035e-05	55.0	COG2244@1|root,COG2244@2|Bacteria,1G3H8@1117|Cyanobacteria,1H7IC@1150|Oscillatoriales	1117|Cyanobacteria	S	Membrane protein involved in the export of o-antigen and teichoic acid	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
WLSH3_k127_30580_2	1144275.COCOR_02518	1.79e-15	76.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,2YUNU@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WLSH3_k127_30580_0	264732.Moth_2293	1.03e-96	325.0	COG2309@1|root,COG2309@2|Bacteria,1UMYG@1239|Firmicutes,24BYI@186801|Clostridia,42GN7@68295|Thermoanaerobacterales	186801|Clostridia	E	Thermophilic metalloprotease (M29)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
WLSH3_k127_30580_1	1499967.BAYZ01000057_gene4682	7.116e-49	196.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WLSH3_k127_30580_3	1122217.KB899568_gene797	5.286e-08	66.0	COG2911@1|root,COG2911@2|Bacteria,1TQZZ@1239|Firmicutes,4H2F1@909932|Negativicutes	909932|Negativicutes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	AsmA_2,TamB
WLSH3_k127_3071419_4	511051.CSE_00380	4.938e-64	221.0	COG4275@1|root,COG4275@2|Bacteria	2|Bacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
WLSH3_k127_3071419_1	1304874.JAFY01000002_gene661	1.703e-169	541.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_3071419_2	335543.Sfum_2649	1.12e-168	541.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2MQ96@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WLSH3_k127_3071419_3	1340434.AXVA01000007_gene5237	8.313e-164	524.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,1ZAV3@1386|Bacillus	91061|Bacilli	E	Catalyzes the interconversion of ornithine to glutamate semialdehyde	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009064,GO:0009987,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
WLSH3_k127_3071419_0	857293.CAAU_0251	5.44e-208	662.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,36E27@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
WLSH3_k127_3071419_5	457570.Nther_2697	2.417e-55	199.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia	186801|Clostridia	C	indolepyruvate ferredoxin oxidoreductase beta subunit	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
WLSH3_k127_3071633_1	370438.PTH_2004	8.31e-126	436.0	COG2199@1|root,COG2202@1|root,COG2206@1|root,COG3829@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,267B5@186807|Peptococcaceae	186801|Clostridia	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9
WLSH3_k127_3071633_2	1162668.LFE_1514	1.908e-92	312.0	COG0421@1|root,COG0421@2|Bacteria,3J0Y5@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
WLSH3_k127_3071633_0	321327.CYA_1002	1.201e-139	459.0	COG1982@1|root,COG1982@2|Bacteria,1G1TA@1117|Cyanobacteria,1GYMZ@1129|Synechococcus	1117|Cyanobacteria	E	Orn Lys Arg decarboxylase	cad	-	4.1.1.18	ko:K01582	ko00310,ko00960,ko01100,ko01110,map00310,map00960,map01100,map01110	-	R00462	RC00299	ko00000,ko00001,ko01000	-	-	iJN678.cad	OKR_DC_1,OKR_DC_1_C
WLSH3_k127_3078403_0	1379698.RBG1_1C00001G1096	9.487e-111	364.0	COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WLSH3_k127_3078403_1	1379698.RBG1_1C00001G1828	2.625e-100	340.0	COG0416@1|root,COG0416@2|Bacteria,2NP1H@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WLSH3_k127_3078403_4	1379698.RBG1_1C00001G1829	9.463e-21	92.0	COG0333@1|root,COG0333@2|Bacteria,2NQ1M@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L32p protein family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WLSH3_k127_3078403_2	926692.AZYG01000036_gene2563	8.378e-86	294.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WAQK@53433|Halanaerobiales	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WLSH3_k127_3078403_5	717772.THIAE_04500	4.079e-12	76.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,45ZPR@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
WLSH3_k127_3078403_3	1121015.N789_07665	1.183e-59	214.0	COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,1T04X@1236|Gammaproteobacteria,1XCYU@135614|Xanthomonadales	135614|Xanthomonadales	CP	Sodium ABC transporter permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3
WLSH3_k127_3094180_2	379066.GAU_2570	5.826e-07	51.0	COG2804@1|root,COG2804@2|Bacteria,1ZSSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH3_k127_3094180_0	404380.Gbem_2594	5.313e-142	458.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH3_k127_3094180_1	706587.Desti_3122	5.52e-65	228.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2MQAH@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WLSH3_k127_3139259_0	1191523.MROS_0941	5.059e-105	349.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WLSH3_k127_3139259_1	1191523.MROS_0942	3.238e-49	184.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WLSH3_k127_3155260_1	1192034.CAP_7146	3.273e-26	116.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2WT4M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
WLSH3_k127_3155260_0	357808.RoseRS_0862	9.812e-46	173.0	COG0423@1|root,COG0423@2|Bacteria,2G62M@200795|Chloroflexi,376EQ@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
WLSH3_k127_3230042_4	55529.EKX52466	8.467e-05	50.0	COG0451@1|root,COG0457@1|root,KOG1430@2759|Eukaryota,KOG1840@2759|Eukaryota	2759|Eukaryota	C	determination of stomach left/right asymmetry	-	-	-	-	-	-	-	-	-	-	-	-	3Beta_HSD,DUF4062,Epimerase,NACHT,Pkinase,TIG,TPR_10,TPR_12
WLSH3_k127_3230042_0	269799.Gmet_0916	2.021e-128	418.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,43UB6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WLSH3_k127_3230042_1	1379698.RBG1_1C00001G0497	1.05e-31	132.0	COG0811@1|root,COG0811@2|Bacteria,2NPFR@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
WLSH3_k127_3230042_2	1379698.RBG1_1C00001G0498	3.351e-28	118.0	COG0848@1|root,COG0848@2|Bacteria,2NPWJ@2323|unclassified Bacteria	2|Bacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
WLSH3_k127_3230042_3	1379698.RBG1_1C00001G0499	3.218e-27	123.0	COG0810@1|root,COG0810@2|Bacteria,2NQ3G@2323|unclassified Bacteria	2|Bacteria	M	TonB C terminal	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	CarbopepD_reg_2,TonB_2,TonB_C
WLSH3_k127_3262913_0	1379698.RBG1_1C00001G0876	5.066e-144	466.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_3262913_2	1304880.JAGB01000004_gene1399	1.178e-06	56.0	COG1633@1|root,COG1633@2|Bacteria,1VGHR@1239|Firmicutes,24QXX@186801|Clostridia	186801|Clostridia	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH3_k127_3262913_1	1280954.HPO_17746	1.311e-16	87.0	COG0436@1|root,COG0436@2|Bacteria,1R3UB@1224|Proteobacteria,2U497@28211|Alphaproteobacteria,43Z8T@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WLSH3_k127_3291859_0	398767.Glov_3187	2.602e-193	620.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
WLSH3_k127_3291859_1	1173028.ANKO01000116_gene5719	1.04e-62	221.0	COG2114@1|root,COG2114@2|Bacteria,1G6D6@1117|Cyanobacteria,1HB2S@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WLSH3_k127_3335678_1	926550.CLDAP_36340	6.269e-107	356.0	COG2605@1|root,COG2605@2|Bacteria,2G5TF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM GHMP kinase	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
WLSH3_k127_3335678_0	439235.Dalk_1696	1.75e-141	458.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,42R49@68525|delta/epsilon subdivisions,2WNEZ@28221|Deltaproteobacteria,2MN63@213118|Desulfobacterales	28221|Deltaproteobacteria	M	NAD(P)H-binding	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
WLSH3_k127_3335678_2	1321778.HMPREF1982_02796	9.415e-75	259.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia	186801|Clostridia	JM	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WLSH3_k127_3335678_3	530564.Psta_1375	2.169e-51	190.0	COG0279@1|root,COG0279@2|Bacteria,2IZ19@203682|Planctomycetes	203682|Planctomycetes	G	Phosphoheptose isomerase	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WLSH3_k127_3335678_4	509190.Cseg_1874	1.63e-33	135.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2UFIH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
WLSH3_k127_335906_2	360094.PXO_01741	7.527e-28	118.0	COG2199@1|root,COG2203@1|root,COG5278@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG5278@2|Bacteria,1NECV@1224|Proteobacteria,1S1ZR@1236|Gammaproteobacteria,1X71E@135614|Xanthomonadales	135614|Xanthomonadales	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,GGDEF
WLSH3_k127_335906_0	481448.Minf_0010	5.053e-157	506.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WLSH3_k127_335906_1	926550.CLDAP_15490	2.962e-132	431.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WLSH3_k127_335906_3	469383.Cwoe_3709	8.185e-13	77.0	COG1807@1|root,COG1807@2|Bacteria,2HNIC@201174|Actinobacteria,4CPHR@84995|Rubrobacteria	84995|Rubrobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WLSH3_k127_3361660_2	153721.MYP_1067	2.012e-22	101.0	COG0652@1|root,COG0652@2|Bacteria,4NGT6@976|Bacteroidetes,47MY6@768503|Cytophagia	976|Bacteroidetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
WLSH3_k127_3361660_0	404589.Anae109_2092	1.122e-111	380.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
WLSH3_k127_3361660_1	215803.DB30_2825	2.422e-68	265.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1QWVY@1224|Proteobacteria,43909@68525|delta/epsilon subdivisions,2X45B@28221|Deltaproteobacteria,2YYAK@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase
WLSH3_k127_3379669_1	880073.Calab_1553	1.91e-51	189.0	COG2908@1|root,COG2908@2|Bacteria,2NPKW@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
WLSH3_k127_3379669_0	1123371.ATXH01000001_gene1289	1.229e-174	558.0	COG0148@1|root,COG0148@2|Bacteria,2GH1M@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WLSH3_k127_3379669_3	338963.Pcar_0741	2.937e-05	50.0	COG2919@1|root,COG2919@2|Bacteria,1NM5U@1224|Proteobacteria,42X2K@68525|delta/epsilon subdivisions,2WSPM@28221|Deltaproteobacteria,43VHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
WLSH3_k127_3379669_2	644107.SL1157_0518	5.732e-07	51.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3388458_1	1232410.KI421424_gene1860	1.797e-38	146.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43RZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
WLSH3_k127_3388458_0	635013.TherJR_2099	1.194e-201	649.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WLSH3_k127_3395619_0	909663.KI867150_gene1425	2.27e-89	299.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WLSH3_k127_3395619_1	1121918.ARWE01000001_gene2103	6.976e-38	147.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH3_k127_3395619_3	1047013.AQSP01000092_gene326	7.279e-25	106.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
WLSH3_k127_3395619_2	234267.Acid_7868	6.548e-37	143.0	COG1230@1|root,COG1230@2|Bacteria,3Y32W@57723|Acidobacteria	57723|Acidobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
WLSH3_k127_3408743_3	316067.Geob_1816	1.476e-18	87.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WLSH3_k127_3408743_2	1379698.RBG1_1C00001G1177	4.051e-24	106.0	COG0789@1|root,COG0789@2|Bacteria,2NQ3P@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, mercury resistance	ycgE	-	-	ko:K19591,ko:K22491	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR_1
WLSH3_k127_3408743_1	428125.CLOLEP_01578	9.929e-34	139.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3WHV2@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WLSH3_k127_3408743_0	1382306.JNIM01000001_gene4140	5.666e-97	327.0	COG0240@1|root,COG0240@2|Bacteria,2G5W5@200795|Chloroflexi	200795|Chloroflexi	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WLSH3_k127_3439568_0	1449126.JQKL01000008_gene293	3.238e-186	591.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,267RV@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WLSH3_k127_343998_0	1379698.RBG1_1C00001G0415	7.017e-139	452.0	COG5316@1|root,COG5316@2|Bacteria,2NPBR@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
WLSH3_k127_343998_1	1379698.RBG1_1C00001G1510	6.944e-116	388.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_343998_2	377629.TERTU_1146	9.573e-08	56.0	2ATYA@1|root,31JHY@2|Bacteria,1QAXH@1224|Proteobacteria,1T6D5@1236|Gammaproteobacteria,2PQK4@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3456641_0	255470.cbdbA943	9.254e-178	560.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,34CJX@301297|Dehalococcoidia	301297|Dehalococcoidia	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
WLSH3_k127_3456641_1	1121440.AUMA01000006_gene1505	4.382e-55	201.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,2M82V@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WLSH3_k127_3456641_2	246197.MXAN_5744	2.916e-12	71.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2YZGM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WLSH3_k127_3530957_5	314230.DSM3645_28987	0.0002044	53.0	COG3391@1|root,COG3391@2|Bacteria,2IZ8H@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
WLSH3_k127_3530957_4	521011.Mpal_1345	7.811e-26	122.0	COG0614@1|root,arCOG03561@1|root,arCOG03561@2157|Archaea,arCOG03611@2157|Archaea,2Y1Q9@28890|Euryarchaeota,2N9M9@224756|Methanomicrobia	224756|Methanomicrobia	P	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,NHL
WLSH3_k127_3530957_3	1131269.AQVV01000009_gene1100	1.695e-40	170.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
WLSH3_k127_3530957_1	1499967.BAYZ01000160_gene414	1.363e-95	327.0	COG1524@1|root,COG1524@2|Bacteria,2NQ0M@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WLSH3_k127_3530957_2	1313172.YM304_23460	8.204e-58	221.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4CN0A@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WLSH3_k127_3530957_0	378806.STAUR_6405	6.699e-148	482.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
WLSH3_k127_3587987_2	410358.Mlab_0472	0.0009651	49.0	arCOG07446@1|root,arCOG07446@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3587987_1	880073.Calab_2091	5.325e-55	201.0	2CBA8@1|root,30BZT@2|Bacteria,2NR2H@2323|unclassified Bacteria	2|Bacteria	S	Exopolysaccharide biosynthesis protein YbjH	-	-	-	-	-	-	-	-	-	-	-	-	YjbH
WLSH3_k127_3587987_0	478741.JAFS01000001_gene2152	1.902e-319	1014.0	COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,37G41@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Bacterial DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WLSH3_k127_3619968_0	635013.TherJR_2972	1.05e-125	413.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,260E3@186807|Peptococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WLSH3_k127_3619968_2	56780.SYN_02178	1.306e-75	264.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2MQDY@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WLSH3_k127_3619968_1	1009370.ALO_14557	5.798e-104	351.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes	909932|Negativicutes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WLSH3_k127_3619968_4	429009.Adeg_0844	3.837e-05	49.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
WLSH3_k127_3619968_3	1064535.MELS_1767	2.771e-47	175.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4H3ZW@909932|Negativicutes	909932|Negativicutes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WLSH3_k127_3629935_2	767817.Desgi_2585	1.316e-37	144.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,261KE@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WLSH3_k127_3629935_0	592015.HMPREF1705_00964	2.511e-104	344.0	COG1013@1|root,COG1013@2|Bacteria,3T9RK@508458|Synergistetes	508458|Synergistetes	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH3_k127_3629935_1	484770.UFO1_2346	7.255e-76	265.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,4H3AM@909932|Negativicutes	909932|Negativicutes	C	ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH3_k127_3663865_0	197221.22296114	1.975e-88	301.0	COG1216@1|root,COG1216@2|Bacteria,1G2TX@1117|Cyanobacteria	1117|Cyanobacteria	Q	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3663865_1	118161.KB235922_gene2058	7.028e-43	165.0	COG0438@1|root,COG0438@2|Bacteria,1G1VE@1117|Cyanobacteria,3VI2A@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Methyltransf_11
WLSH3_k127_3695544_0	1121373.KB903629_gene362	1.416e-55	207.0	COG0457@1|root,COG0457@2|Bacteria	1121373.KB903629_gene362|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3695544_2	1047013.AQSP01000140_gene2513	4.248e-39	148.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
WLSH3_k127_3695544_1	1047013.AQSP01000140_gene2513	3.694e-52	193.0	COG1322@1|root,COG1322@2|Bacteria,2NPXU@2323|unclassified Bacteria	2|Bacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
WLSH3_k127_3695544_3	1480694.DC28_07915	4.679e-36	146.0	COG1752@1|root,COG1752@2|Bacteria,2J6JW@203691|Spirochaetes	203691|Spirochaetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
WLSH3_k127_3698096_0	1047013.AQSP01000074_gene1894	5.444e-82	278.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WLSH3_k127_3698096_2	1232410.KI421428_gene1248	6.939e-36	141.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2WQQ4@28221|Deltaproteobacteria,43SHB@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
WLSH3_k127_3698096_5	518766.Rmar_0860	1.675e-13	72.0	COG1841@1|root,COG1841@2|Bacteria,4NUXV@976|Bacteroidetes	976|Bacteroidetes	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
WLSH3_k127_3698096_1	944564.HMPREF9200_1310	4.112e-52	190.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4H3Z7@909932|Negativicutes	909932|Negativicutes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
WLSH3_k127_3698096_3	562743.JH976443_gene3437	5.54e-35	137.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli	91061|Bacilli	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
WLSH3_k127_3698096_4	1415775.U729_1361	1.05e-15	77.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,36FMT@31979|Clostridiaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
WLSH3_k127_3704988_0	1121423.JONT01000012_gene422	2.393e-132	431.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,260DK@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WLSH3_k127_3704988_4	391587.KAOT1_09706	1.836e-18	95.0	2DBB3@1|root,2Z85F@2|Bacteria,4NKCY@976|Bacteroidetes,1HZTC@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846
WLSH3_k127_3704988_2	313606.M23134_01115	8.706e-56	208.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,4NHRI@976|Bacteroidetes,47KP6@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH3_k127_3704988_1	215803.DB30_5113	5.502e-104	353.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,4382G@68525|delta/epsilon subdivisions,2X3CI@28221|Deltaproteobacteria,2YVET@29|Myxococcales	28221|Deltaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
WLSH3_k127_3704988_3	561175.KB894099_gene4935	4.474e-24	111.0	COG0457@1|root,COG0457@2|Bacteria,2I9VA@201174|Actinobacteria	201174|Actinobacteria	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,TPR_16
WLSH3_k127_3707776_1	459349.CLOAM0985	1.934e-35	155.0	COG1361@1|root,COG1361@2|Bacteria,2NQI0@2323|unclassified Bacteria	2|Bacteria	M	FlgD Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
WLSH3_k127_3707776_0	1278073.MYSTI_05912	4.753e-51	192.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2YWSU@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH3_k127_3707776_2	443143.GM18_1338	4.825e-28	115.0	COG2843@1|root,COG2843@2|Bacteria	2|Bacteria	M	Bacterial capsule synthesis protein PGA_cap	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
WLSH3_k127_3710648_1	868131.MSWAN_1258	3.227e-58	211.0	arCOG03165@1|root,arCOG03165@2157|Archaea,2XXAZ@28890|Euryarchaeota,23PM9@183925|Methanobacteria	183925|Methanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3710648_0	945713.IALB_0513	6.701e-115	374.0	COG0708@1|root,COG0708@2|Bacteria	2|Bacteria	L	double-stranded DNA 3'-5' exodeoxyribonuclease activity	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WLSH3_k127_3710648_2	1122138.AQUZ01000012_gene6041	1.861e-50	188.0	2C1EG@1|root,2Z7MZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3712369_1	335543.Sfum_3909	6.973e-47	177.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WN2R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
WLSH3_k127_3712369_0	1291050.JAGE01000001_gene62	5.963e-99	336.0	COG0477@1|root,COG2814@2|Bacteria,1V19N@1239|Firmicutes	1239|Firmicutes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_3712369_2	1379698.RBG1_1C00001G0873	1.014e-29	126.0	COG0237@1|root,COG0237@2|Bacteria,2NPMB@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24,2.7.7.87	ko:K00859,ko:K07566	ko00770,ko01100,map00770,map01100	M00120	R00130,R10463	RC00002,RC00078,RC00745	ko00000,ko00001,ko00002,ko01000,ko03009,ko03016	-	-	-	CoaE
WLSH3_k127_3838744_0	518766.Rmar_0508	1.644e-73	281.0	COG2203@1|root,COG2204@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	Sigma54_activat
WLSH3_k127_3846952_0	562970.Btus_3319	1.973e-110	372.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,27824@186823|Alicyclobacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WLSH3_k127_3846952_2	243231.GSU2794	9.991e-54	192.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,43V0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WLSH3_k127_3846952_3	398512.JQKC01000026_gene3792	4.161e-45	173.0	294DM@1|root,2ZRTK@2|Bacteria,1V7PN@1239|Firmicutes,25DBP@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4184)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184
WLSH3_k127_3846952_1	509191.AEDB02000084_gene5186	4.806e-64	228.0	COG1073@1|root,COG1073@2|Bacteria,1V7R5@1239|Firmicutes,25D2R@186801|Clostridia,3WMD1@541000|Ruminococcaceae	186801|Clostridia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3874189_3	1499967.BAYZ01000147_gene697	8.438e-10	61.0	COG1839@1|root,COG1839@2|Bacteria,2NPAQ@2323|unclassified Bacteria	2|Bacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
WLSH3_k127_3874189_1	1094508.Tsac_0541	9.904e-76	264.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WLSH3_k127_3874189_4	1045858.Bint_0808	1.939e-07	60.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	tse	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
WLSH3_k127_3874189_0	1121428.DESHY_30017___1	4.12e-98	327.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,2603P@186807|Peptococcaceae	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WLSH3_k127_3892229_2	632292.Calhy_1814	3.526e-64	224.0	COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,42EUF@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH3_k127_3892229_3	1499967.BAYZ01000016_gene6492	2.114e-34	140.0	COG1144@1|root,COG1144@2|Bacteria,2NRX4@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase	porD	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00171,ko:K00172,ko:K19072	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,Fer4_21,POR
WLSH3_k127_3892229_1	926692.AZYG01000051_gene1856	1.863e-64	227.0	COG1014@1|root,COG1014@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia,3WBNH@53433|Halanaerobiales	186801|Clostridia	C	TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family	porC	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WLSH3_k127_3892229_0	370438.PTH_1049	3.167e-216	685.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,260AT@186807|Peptococcaceae	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WLSH3_k127_3917250_1	1150469.RSPPHO_01228	1.754e-68	236.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,2JQ8H@204441|Rhodospirillales	204441|Rhodospirillales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WLSH3_k127_3917250_2	867903.ThesuDRAFT_00566	4.3e-62	216.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WCGY@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
WLSH3_k127_3917250_8	1379698.RBG1_1C00001G1588	2.52e-09	61.0	COG0255@1|root,COG0255@2|Bacteria,2NQ49@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal L29 protein	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
WLSH3_k127_3917250_6	658655.HMPREF0988_01330	4.891e-30	120.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,27NW5@186928|unclassified Lachnospiraceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
WLSH3_k127_3917250_3	880073.Calab_2136	8.21e-53	188.0	COG0093@1|root,COG0093@2|Bacteria,2NPCS@2323|unclassified Bacteria	2|Bacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
WLSH3_k127_3917250_5	246194.CHY_2298	6.061e-34	133.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,42GS5@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
WLSH3_k127_3917250_0	1121428.DESHY_150054___1	8.612e-79	267.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,2603I@186807|Peptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
WLSH3_k127_3917250_7	469378.Ccur_09870	5.33e-23	98.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CWG8@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
WLSH3_k127_3917250_4	269799.Gmet_0640	3.005e-45	167.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,43V2C@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
WLSH3_k127_3923689_3	1499967.BAYZ01000136_gene51	6.321e-07	57.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG4916@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,COG4916@2|Bacteria,2NR2E@2323|unclassified Bacteria	2|Bacteria	T	AAA ATPase domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,Guanylate_cyc,TIR_2,TPR_12,TPR_7
WLSH3_k127_3923689_2	1254432.SCE1572_34345	4.328e-25	120.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1NB06@1224|Proteobacteria,43AS1@68525|delta/epsilon subdivisions,2X665@28221|Deltaproteobacteria,2YYB2@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_12,TPR_8
WLSH3_k127_3923689_1	224325.AF_0029	1.682e-25	112.0	COG1504@1|root,arCOG04337@2157|Archaea,2Y6F4@28890|Euryarchaeota,247CC@183980|Archaeoglobi	183980|Archaeoglobi	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
WLSH3_k127_3923689_0	1121373.KB903629_gene362	8.93e-34	145.0	COG0457@1|root,COG0457@2|Bacteria	1121373.KB903629_gene362|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_393242_0	216432.CA2559_13653	2.213e-10	74.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,4NG16@976|Bacteroidetes,1HY10@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SdrD_B
WLSH3_k127_3939051_2	1305737.JAFX01000001_gene2143	3.743e-09	64.0	COG1286@1|root,COG1286@2|Bacteria,4NYKG@976|Bacteroidetes	976|Bacteroidetes	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
WLSH3_k127_3939051_0	370438.PTH_1939	1.309e-165	548.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WLSH3_k127_3939051_1	1304880.JAGB01000001_gene547	2.091e-18	85.0	COG0454@1|root,COG0456@2|Bacteria,1TT30@1239|Firmicutes,24DE0@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH3_k127_3966836_1	648996.Theam_1402	1.803e-42	160.0	COG0194@1|root,COG0194@2|Bacteria,2G3ZQ@200783|Aquificae	200783|Aquificae	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WLSH3_k127_3966836_0	1378168.N510_02453	3.831e-62	224.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes	1239|Firmicutes	S	Stress-induced protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
WLSH3_k127_3966836_4	1177181.T9A_00112	7.203e-11	70.0	290UJ@1|root,2ZNGJ@2|Bacteria,1RBSP@1224|Proteobacteria,1S3RZ@1236|Gammaproteobacteria,1XKS8@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3966836_3	313606.M23134_08189	3.289e-21	105.0	2F8DC@1|root,340S7@2|Bacteria,4P4TH@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_3966836_2	1123376.AUIU01000014_gene636	4.221e-24	108.0	COG1449@1|root,COG1449@2|Bacteria,3J0AQ@40117|Nitrospirae	40117|Nitrospirae	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
WLSH3_k127_3971375_0	439235.Dalk_0743	0.0003186	50.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria,2MHV1@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
WLSH3_k127_398094_4	517418.Ctha_0653	1.394e-22	99.0	COG0629@1|root,COG0629@2|Bacteria,1FDUC@1090|Chlorobi	1090|Chlorobi	L	PFAM single-strand binding protein Primosomal replication protein n	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH3_k127_398094_3	318464.IO99_07810	1.814e-24	105.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WLSH3_k127_398094_1	880073.Calab_2408	2.261e-43	162.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WLSH3_k127_398094_2	1379270.AUXF01000006_gene147	1.959e-34	138.0	COG1762@1|root,COG1762@2|Bacteria,1ZTIY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
WLSH3_k127_398094_8	1379281.AVAG01000003_gene184	2.202e-10	66.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,2M888@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
WLSH3_k127_398094_5	682795.AciX8_0504	5.934e-20	90.0	COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria,2JJYY@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WLSH3_k127_398094_0	1379698.RBG1_1C00001G0634	4.321e-51	186.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
WLSH3_k127_398094_6	204669.Acid345_0556	5.238e-15	84.0	COG0816@1|root,COG0816@2|Bacteria,3Y59A@57723|Acidobacteria,2JP2U@204432|Acidobacteriia	204432|Acidobacteriia	J	Likely ribonuclease with RNase H fold.	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WLSH3_k127_398094_7	1510531.JQJJ01000011_gene2784	7.369e-11	67.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,3JSZJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WLSH3_k127_3992397_0	1254432.SCE1572_00510	7.044e-83	285.0	COG2207@1|root,COG3449@1|root,COG2207@2|Bacteria,COG3449@2|Bacteria,1MWTF@1224|Proteobacteria,42PYD@68525|delta/epsilon subdivisions,2X02K@28221|Deltaproteobacteria,2Z0PX@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
WLSH3_k127_3992397_2	1114856.C496_00415	5.929e-20	98.0	arCOG03085@1|root,arCOG03085@2157|Archaea,2XWPM@28890|Euryarchaeota,23VFX@183963|Halobacteria	183963|Halobacteria	T	Putative sensor	-	-	-	-	-	-	-	-	-	-	-	-	Sensor
WLSH3_k127_3992397_1	582515.KR51_00017790	5.473e-30	121.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
WLSH3_k127_3992397_3	1208921.ST1E_0449	5.552e-17	83.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,1KQBA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
WLSH3_k127_4048820_1	748449.Halha_1848	4.968e-05	51.0	COG0513@1|root,COG0608@1|root,COG0513@2|Bacteria,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3WB7F@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
WLSH3_k127_4048820_0	1347086.CCBA010000027_gene3598	1.21e-108	362.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,1ZBDW@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	msmX	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
WLSH3_k127_4078146_0	1379698.RBG1_1C00001G1855	1.15e-195	617.0	COG0499@1|root,COG0499@2|Bacteria,2NNQE@2323|unclassified Bacteria	2|Bacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WLSH3_k127_4078146_2	880073.Calab_2504	2.047e-61	227.0	COG0795@1|root,COG0795@2|Bacteria,2NPHN@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WLSH3_k127_4078146_1	1379698.RBG1_1C00001G1858	1.971e-92	317.0	COG0795@1|root,COG0795@2|Bacteria,2NP9S@2323|unclassified Bacteria	2|Bacteria	S	Permease YjgP YjgQ family protein	lptF	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K07091,ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	iECED1_1282.ECED1_5114,iUMNK88_1353.UMNK88_5207	YjgP_YjgQ
WLSH3_k127_4078146_3	1379698.RBG1_1C00001G0435	2.226e-34	151.0	COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
WLSH3_k127_4135583_0	1347342.BN863_33650	1.95e-169	539.0	COG0615@1|root,COG2605@1|root,COG0615@2|Bacteria,COG2605@2|Bacteria,4NGSD@976|Bacteroidetes	976|Bacteroidetes	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GHMP_kinases_C
WLSH3_k127_4135583_1	1408473.JHXO01000007_gene716	2.845e-53	193.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,4NF52@976|Bacteroidetes,2FM64@200643|Bacteroidia	976|Bacteroidetes	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
WLSH3_k127_4154419_0	1379270.AUXF01000006_gene304	2.764e-210	666.0	COG0542@1|root,COG0542@2|Bacteria,1ZTBV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Clp amino terminal domain, pathogenicity island component	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WLSH3_k127_4154419_1	1379698.RBG1_1C00001G0446	3.009e-80	281.0	COG3869@1|root,COG3869@2|Bacteria,2NR28@2323|unclassified Bacteria	2|Bacteria	E	ATP:guanido phosphotransferase, C-terminal catalytic domain	mcsB	GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170	2.7.14.1,2.7.3.2,2.7.3.3	ko:K00933,ko:K00934,ko:K19405	ko00330,ko01100,map00330,map01100	M00047	R00554,R01881,R11090	RC00002,RC00203	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ATP-gua_Ptrans
WLSH3_k127_4154419_2	2325.TKV_c20930	8.411e-31	127.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,24JE8@186801|Clostridia,42G0X@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
WLSH3_k127_4154419_3	443143.GM18_0167	5.21e-23	104.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,43TS2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH3_k127_4162410_0	56780.SYN_00928	1.33e-77	265.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2MR8P@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WLSH3_k127_4162410_2	68170.KL590470_gene11213	4.814e-08	65.0	COG3595@1|root,COG3595@2|Bacteria,2I8IR@201174|Actinobacteria,4E6FZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WLSH3_k127_4162410_1	526227.Mesil_1970	2.931e-50	195.0	COG0366@1|root,COG0366@2|Bacteria,1WM5F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
WLSH3_k127_4166259_0	1047013.AQSP01000140_gene2549	5.998e-174	562.0	COG1067@1|root,COG1067@2|Bacteria,2NP29@2323|unclassified Bacteria	2|Bacteria	O	peptidase S16	ycbZ	-	3.4.21.53	ko:K01338,ko:K04076,ko:K04770	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA_32,Lon_C
WLSH3_k127_4166259_1	1303518.CCALI_01677	7.478e-15	80.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wbdA	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WLSH3_k127_4166259_2	754476.Q7A_1540	1.6e-07	61.0	COG3307@1|root,COG3307@2|Bacteria,1R841@1224|Proteobacteria,1SG4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	macromolecule glycosylation	-	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	PglL_A,Wzy_C,Wzy_C_2
WLSH3_k127_4169264_0	880073.Calab_0201	1.917e-131	447.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2NNYS@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III, epsilon subunit	dinG	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,Helicase_C_2,RNase_T,ResIII
WLSH3_k127_4193413_1	888727.HMPREF9092_0580	8.739e-34	133.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3WCPT@538999|Clostridiales incertae sedis	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
WLSH3_k127_4193413_2	1158338.JNLJ01000001_gene905	2.907e-19	103.0	COG2885@1|root,COG2885@2|Bacteria,2G4S4@200783|Aquificae	200783|Aquificae	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_YMGG,OmpA,TSP_3
WLSH3_k127_4193413_4	515635.Dtur_1219	1.351e-09	71.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WLSH3_k127_4193413_0	1382356.JQMP01000003_gene2017	1.374e-39	158.0	COG0697@1|root,COG0697@2|Bacteria,2G7RS@200795|Chloroflexi,27YZ0@189775|Thermomicrobia	189775|Thermomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH3_k127_4193413_3	1379698.RBG1_1C00001G0859	7.097e-14	73.0	COG0697@1|root,COG0697@2|Bacteria,2NPMX@2323|unclassified Bacteria	2|Bacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH3_k127_4204615_2	864069.MicloDRAFT_00023220	1.261e-05	49.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,1JRWU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	ATPase component of ABC-type sugar transporter	-	-	-	ko:K10111,ko:K10112,ko:K10191	ko02010,map02010	M00194,M00196,M00197,M00199,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.4	-	-	ABC_tran,TOBE,TOBE_2
WLSH3_k127_4204615_1	1519464.HY22_06715	2.717e-12	76.0	COG1729@1|root,COG1729@2|Bacteria,1FEBS@1090|Chlorobi	1090|Chlorobi	S	PFAM Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6
WLSH3_k127_4204615_0	1123376.AUIU01000014_gene636	1.153e-165	540.0	COG1449@1|root,COG1449@2|Bacteria,3J0AQ@40117|Nitrospirae	40117|Nitrospirae	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
WLSH3_k127_4206259_3	926550.CLDAP_35050	2.581e-16	79.0	COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi	200795|Chloroflexi	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_5,LMWPc
WLSH3_k127_4206259_2	247490.KSU1_B0729	5.941e-57	205.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WLSH3_k127_4206259_0	649747.HMPREF0083_00886	5.293e-98	326.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli,26SPV@186822|Paenibacillaceae	91061|Bacilli	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	iSB619.SA_RS06920	ABC_tran
WLSH3_k127_4206259_1	1242864.D187_004631	6.595e-89	299.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
WLSH3_k127_4249392_2	1536772.R70723_04640	0.000838	46.0	COG0463@1|root,COG0463@2|Bacteria,1V1GY@1239|Firmicutes,4ISP2@91061|Bacilli,26U2S@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyl transferase	waaE	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH3_k127_4249392_0	1379698.RBG1_1C00001G0211	6.399e-45	181.0	COG0457@1|root,COG0457@2|Bacteria,2NQ8S@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4249392_1	572546.Arcpr_0713	2.098e-40	157.0	COG0644@1|root,arCOG00570@2157|Archaea,2XU3J@28890|Euryarchaeota,245QU@183980|Archaeoglobi	183980|Archaeoglobi	C	Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains	-	-	1.3.1.101,1.3.7.11	ko:K17830	ko00564,map00564	-	R10325,R10326,R10331	RC03134	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
WLSH3_k127_4254067_1	1379698.RBG1_1C00001G0387	1.933e-27	117.0	COG2001@1|root,COG2001@2|Bacteria,2NPTY@2323|unclassified Bacteria	2|Bacteria	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WLSH3_k127_4254067_2	378806.STAUR_6271	1.197e-14	79.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4,STAS,STAS_2
WLSH3_k127_4254067_0	562970.Btus_1865	6.506e-89	304.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli,2797Y@186823|Alicyclobacillaceae	91061|Bacilli	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WLSH3_k127_4279974_10	1229172.JQFA01000004_gene1645	6.34e-08	59.0	COG0835@1|root,COG0835@2|Bacteria,1G1KW@1117|Cyanobacteria,1H9PA@1150|Oscillatoriales	1117|Cyanobacteria	NT	Chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WLSH3_k127_4279974_4	861299.J421_3064	2.955e-44	172.0	COG0457@1|root,COG0457@2|Bacteria,1ZTK5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
WLSH3_k127_4279974_0	635013.TherJR_0113	8.004e-99	333.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia,260YB@186807|Peptococcaceae	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WLSH3_k127_4279974_6	1122915.AUGY01000028_gene5950	9.432e-37	144.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,4HIVG@91061|Bacilli,26X6R@186822|Paenibacillaceae	91061|Bacilli	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
WLSH3_k127_4279974_3	1094980.Mpsy_2595	7.553e-53	196.0	COG1352@1|root,arCOG04402@2157|Archaea,2XU3Q@28890|Euryarchaeota,2N9NH@224756|Methanomicrobia	224756|Methanomicrobia	N	PFAM MCP methyltransferase CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WLSH3_k127_4279974_1	379066.GAU_1412	2.429e-83	297.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
WLSH3_k127_4279974_5	745411.B3C1_06002	5.702e-43	174.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1J5A3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WLSH3_k127_4279974_2	1242864.D187_010497	4.008e-79	268.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
WLSH3_k127_4279974_7	309799.DICTH_1243	6.583e-18	92.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
WLSH3_k127_4279974_8	877455.Metbo_0652	2.212e-12	71.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Roadblock LC7 family protein	-	GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
WLSH3_k127_4279974_9	638303.Thal_0484	3.752e-10	66.0	COG2018@1|root,COG2018@2|Bacteria,2G4D2@200783|Aquificae	200783|Aquificae	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
WLSH3_k127_4296197_0	1379698.RBG1_1C00001G0864	7.191e-58	219.0	COG1452@1|root,COG1452@2|Bacteria,2NPN2@2323|unclassified Bacteria	2|Bacteria	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744,ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC,OstA,OstA_C
WLSH3_k127_4296197_1	1191523.MROS_2396	0.0009536	48.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4332268_1	555079.Toce_1203	3.095e-100	334.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,42F7D@68295|Thermoanaerobacterales	186801|Clostridia	C	Best Blastp hit gi 6685602 sp Q57957 KORB_METJA 2-OXOGLUTARATE SYNTHASE SUBUNIT KORB (2-KETOGLUTARATE OXIDOREDUCTASE BETA CHAIN) (KOR) (2-OXOGLUTARATE-FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) gi 2129229 pir A64367 pyruvate synthase (EC 1.2.7.1) beta chain - Methanococcus jannaschii gi 1591241 gb AAB98531.1 '(U67503) 2-ketoglutarate ferredoxin oxidoreductase, subunit beta (korB) Methanococcus jannaschii ', score	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WLSH3_k127_4332268_2	1125863.JAFN01000001_gene2944	1.287e-55	199.0	COG1014@1|root,COG1014@2|Bacteria,1RAQ4@1224|Proteobacteria,43BEE@68525|delta/epsilon subdivisions,2WN0D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WLSH3_k127_4332268_3	945550.VISI1226_15836	3.062e-45	171.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1XX25@135623|Vibrionales	135623|Vibrionales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WLSH3_k127_4332268_0	1047013.AQSP01000084_gene771	4.016e-170	546.0	COG0282@1|root,COG0282@2|Bacteria,2NNXT@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1034,iNJ661.Rv0409	Acetate_kinase
WLSH3_k127_4339380_2	1298608.JCM18900_11934	2.58e-33	131.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,3NNG8@468|Moraxellaceae	1236|Gammaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WLSH3_k127_4339380_0	411467.BACCAP_04189	2.025e-119	392.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,267UI@186813|unclassified Clostridiales	186801|Clostridia	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WLSH3_k127_4339380_1	247490.KSU1_C1341	1.049e-116	391.0	COG0072@1|root,COG0072@2|Bacteria,2IX0Q@203682|Planctomycetes	203682|Planctomycetes	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WLSH3_k127_4382889_2	1382306.JNIM01000001_gene2944	5.214e-32	126.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi	200795|Chloroflexi	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
WLSH3_k127_4382889_1	880073.Calab_1178	3.279e-45	170.0	COG0558@1|root,COG0558@2|Bacteria,2NPRA@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA1	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,DUF4833
WLSH3_k127_4382889_0	1379698.RBG1_1C00001G0056	5.73e-71	246.0	COG0313@1|root,COG0313@2|Bacteria,2NP98@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WLSH3_k127_4382889_3	1123035.ARLA01000019_gene2713	0.0001769	49.0	COG1404@1|root,COG1404@2|Bacteria,4PM4C@976|Bacteroidetes,1IJJ4@117743|Flavobacteriia,4C2F9@83612|Psychroflexus	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH3_k127_4384214_0	1379698.RBG1_1C00001G0979	6.69e-96	321.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WLSH3_k127_4384214_2	153721.MYP_2720	6.514e-51	201.0	COG2339@1|root,COG2339@2|Bacteria,4NGUS@976|Bacteroidetes,47Q0J@768503|Cytophagia	976|Bacteroidetes	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
WLSH3_k127_4384214_1	880073.Calab_2701	3.168e-67	237.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WLSH3_k127_4384214_3	452637.Oter_2333	4.088e-08	55.0	COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,3K7R2@414999|Opitutae	414999|Opitutae	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WLSH3_k127_4386322_0	1379698.RBG1_1C00001G0568	5.945e-61	213.0	COG1109@1|root,COG1109@2|Bacteria,2NNRE@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iECS88_1305.ECS88_2145,iECUMN_1333.ECUMN_2384,iUTI89_1310.UTI89_C2321	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WLSH3_k127_4386322_1	269798.CHU_0569	2.182e-59	222.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,47MTB@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
WLSH3_k127_4388699_1	316067.Geob_2899	2.623e-94	315.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,43T81@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WLSH3_k127_4388699_0	204669.Acid345_2542	2.518e-138	451.0	COG0126@1|root,COG0126@2|Bacteria,3Y2T7@57723|Acidobacteria,2JI0Z@204432|Acidobacteriia	204432|Acidobacteriia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WLSH3_k127_4388699_2	1009370.ALO_20367	1.784e-65	231.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4H2ZU@909932|Negativicutes	909932|Negativicutes	S	domain protein	gloB	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WLSH3_k127_4390316_1	935836.JAEL01000005_gene2747	7.819e-17	85.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBQ7@91061|Bacilli,1ZBD7@1386|Bacillus	91061|Bacilli	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.23	ko:K13019	ko00520,map00520	-	R09600	RC00290	ko00000,ko00001,ko01000,ko01005	-	-	-	Epimerase_2
WLSH3_k127_4390316_0	760192.Halhy_2051	1.544e-30	139.0	COG0642@1|root,COG0745@1|root,COG2114@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	4.6.1.1	ko:K01768,ko:K16923,ko:K19694	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00582,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.28	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
WLSH3_k127_4393604_0	479434.Sthe_0337	2.664e-118	385.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WLSH3_k127_4393604_1	1121918.ARWE01000001_gene1212	6.977e-118	386.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
WLSH3_k127_4393604_2	290315.Clim_1804	1.422e-30	123.0	COG0005@1|root,COG0005@2|Bacteria,1FDM8@1090|Chlorobi	1090|Chlorobi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WLSH3_k127_4397811_1	1047013.AQSP01000105_gene1454	2.083e-90	301.0	COG2086@1|root,COG2086@2|Bacteria,2NP4J@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WLSH3_k127_4397811_0	1499967.BAYZ01000117_gene3327	2.297e-102	341.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WLSH3_k127_4398075_0	945713.IALB_0461	2.822e-59	232.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WLSH3_k127_4398075_4	511051.CSE_14830	4.288e-22	106.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GGDEF,HATPase_c,HisKA,PAS_9,PilZ,Response_reg,SpoIIE
WLSH3_k127_4398075_7	378806.STAUR_2882	7.976e-05	50.0	COG5544@1|root,COG5544@2|Bacteria,1PD2E@1224|Proteobacteria,435E0@68525|delta/epsilon subdivisions,2WZRI@28221|Deltaproteobacteria,2Z2KM@29|Myxococcales	28221|Deltaproteobacteria	S	Lipoprotein	-	-	-	ko:K05811	-	-	-	-	ko00000	-	-	-	-
WLSH3_k127_4398075_2	1379698.RBG1_1C00001G0490	1.017e-35	148.0	COG2067@1|root,COG2067@2|Bacteria,2NR8A@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4398075_6	945713.IALB_2387	2.338e-05	53.0	2EKPU@1|root,33EDK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4398075_3	1379698.RBG1_1C00001G1439	6.699e-25	106.0	COG2331@1|root,COG2331@2|Bacteria,2NQ36@2323|unclassified Bacteria	2|Bacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH3_k127_4398075_1	459349.CLOAM0891	3.806e-42	177.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
WLSH3_k127_4404829_0	332101.JIBU02000002_gene4610	1.319e-85	296.0	COG0778@1|root,COG0778@2|Bacteria,1UY72@1239|Firmicutes,248YJ@186801|Clostridia,36FEA@31979|Clostridiaceae	186801|Clostridia	C	nitroreductase	sagB	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_4404829_1	9371.XP_004714567.1	8.924e-27	124.0	KOG1130@1|root,KOG1130@2759|Eukaryota,38BEC@33154|Opisthokonta,3BBV7@33208|Metazoa,3CSNR@33213|Bilateria,483EY@7711|Chordata,48YPN@7742|Vertebrata,3J1RC@40674|Mammalia,34TE2@311790|Afrotheria	33208|Metazoa	T	G-protein-signaling modulator 1	GPSM1	GO:0000132,GO:0000139,GO:0000226,GO:0000278,GO:0001709,GO:0001965,GO:0003674,GO:0005092,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0005829,GO:0005886,GO:0005938,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007163,GO:0007275,GO:0007399,GO:0007400,GO:0007405,GO:0008047,GO:0008104,GO:0008150,GO:0008277,GO:0008283,GO:0008356,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009987,GO:0010506,GO:0010508,GO:0010646,GO:0012505,GO:0014016,GO:0014017,GO:0016020,GO:0016043,GO:0016239,GO:0016241,GO:0017145,GO:0019222,GO:0019904,GO:0022008,GO:0022402,GO:0023051,GO:0030010,GO:0030154,GO:0030234,GO:0030695,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0031984,GO:0032091,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0034260,GO:0036445,GO:0040001,GO:0042175,GO:0043085,GO:0043086,GO:0043087,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043547,GO:0044092,GO:0044093,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0045165,GO:0045167,GO:0045175,GO:0045177,GO:0045179,GO:0045185,GO:0048103,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048699,GO:0048731,GO:0048856,GO:0048863,GO:0048865,GO:0048867,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050795,GO:0051098,GO:0051099,GO:0051100,GO:0051179,GO:0051234,GO:0051235,GO:0051293,GO:0051294,GO:0051301,GO:0051336,GO:0051345,GO:0051346,GO:0051640,GO:0051641,GO:0051649,GO:0051653,GO:0051656,GO:0055057,GO:0055059,GO:0060259,GO:0060589,GO:0061351,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071840,GO:0071944,GO:0072089,GO:0098588,GO:0098722,GO:0098772,GO:0098791,GO:0098827,GO:0099568,GO:0099738,GO:1902850,GO:1903047,GO:1904424,GO:1905097,GO:1905098	-	ko:K15837,ko:K15839	ko05030,map05030	-	-	-	ko00000,ko00001,ko03036	-	-	-	GoLoco,TPR_12,TPR_7,TPR_8
WLSH3_k127_4443612_0	635013.TherJR_1393	2.605e-41	155.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24K3X@186801|Clostridia,262BZ@186807|Peptococcaceae	186801|Clostridia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WLSH3_k127_4443612_1	439481.Aboo_0698	3.077e-22	111.0	COG0477@1|root,arCOG00135@2157|Archaea,2XYRS@28890|Euryarchaeota,3F35J@33867|unclassified Euryarchaeota	28890|Euryarchaeota	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,MFS_3
WLSH3_k127_4482777_0	515635.Dtur_1794	1.354e-94	329.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
WLSH3_k127_4482777_2	416591.Tlet_1483	1.678e-34	150.0	COG0613@1|root,COG0613@2|Bacteria,2GCGH@200918|Thermotogae	200918|Thermotogae	L	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4482777_1	1122921.KB898202_gene3138	3.362e-46	181.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli,26QNN@186822|Paenibacillaceae	91061|Bacilli	L	Single-stranded-DNA-specific exonuclease recj	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
WLSH3_k127_4496421_2	945713.IALB_1689	8.727e-25	108.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WLSH3_k127_4496421_0	926566.Terro_0893	5.277e-28	117.0	COG0736@1|root,COG0736@2|Bacteria,3Y590@57723|Acidobacteria,2JJPD@204432|Acidobacteriia	204432|Acidobacteriia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WLSH3_k127_4496421_1	1379698.RBG1_1C00001G0222	4.272e-27	115.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2NNR2@2323|unclassified Bacteria	2|Bacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
WLSH3_k127_4509466_1	1123325.JHUV01000008_gene803	5.02e-32	130.0	COG2027@1|root,COG2027@2|Bacteria	2|Bacteria	M	serine-type D-Ala-D-Ala carboxypeptidase activity	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WLSH3_k127_4509466_0	1379698.RBG1_1C00001G0432	1.917e-54	206.0	2BV2G@1|root,32QFC@2|Bacteria,2NR6X@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4509466_3	1278073.MYSTI_06949	3.376e-18	99.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,DUF4082,F5_F8_type_C,Glyco_hydro_81,KAP_NTPase,WD40
WLSH3_k127_4509466_4	1121430.JMLG01000019_gene1643	1.376e-07	61.0	COG5662@1|root,COG5662@2|Bacteria,1VKS6@1239|Firmicutes,24VD1@186801|Clostridia	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WLSH3_k127_4509466_2	643648.Slip_1965	1.846e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,42K3B@68298|Syntrophomonadaceae	186801|Clostridia	K	RNA polymerase sigma factor	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WLSH3_k127_4520301_0	880073.Calab_1578	1.391e-74	267.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	MdlB	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WLSH3_k127_4520301_1	1444309.JAQG01000033_gene2967	7.212e-66	230.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
WLSH3_k127_4532348_0	448385.sce4660	4.039e-25	109.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2X6ZP@28221|Deltaproteobacteria,2Z3JZ@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WLSH3_k127_4558539_0	643648.Slip_1037	4.071e-61	221.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,42JXF@68298|Syntrophomonadaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WLSH3_k127_4558539_1	1379698.RBG1_1C00001G1781	2.436e-50	189.0	COG0382@1|root,COG0382@2|Bacteria,2NQZV@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39,2.5.1.42	ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00117	R04520,R05000,R05615	RC00209,RC01171,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WLSH3_k127_4565014_0	760568.Desku_0657	1.506e-121	406.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WLSH3_k127_4565014_1	525897.Dbac_0510	0.0002242	50.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WPNX@28221|Deltaproteobacteria,2MDHW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
WLSH3_k127_4586980_1	1121033.AUCF01000032_gene2618	1.65e-28	117.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,2JPTZ@204441|Rhodospirillales	204441|Rhodospirillales	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
WLSH3_k127_4586980_2	1313301.AUGC01000001_gene1508	3.201e-28	124.0	COG0494@1|root,COG0494@2|Bacteria,4NMHV@976|Bacteroidetes	976|Bacteroidetes	L	Pfam NUDIX domain	nudF	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WLSH3_k127_4586980_0	1405.DJ92_4761	3.45e-48	180.0	COG3340@1|root,COG3340@2|Bacteria,1V6ZV@1239|Firmicutes,4HJCZ@91061|Bacilli,1ZHN8@1386|Bacillus	91061|Bacilli	E	Peptidase family S51	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WLSH3_k127_4586980_3	1265502.KB905956_gene148	6.704e-16	83.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,4AG36@80864|Comamonadaceae	28216|Betaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
WLSH3_k127_4586980_4	1121896.JMLU01000057_gene117	1.215e-06	54.0	2E30A@1|root,32Y0V@2|Bacteria,4NPVG@976|Bacteroidetes,1IERS@117743|Flavobacteriia,2NZA8@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4606185_4	391623.TERMP_00349	2.895e-60	212.0	COG1225@1|root,arCOG00310@2157|Archaea,2XY0E@28890|Euryarchaeota,2440M@183968|Thermococci	183968|Thermococci	O	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH3_k127_4606185_5	1379698.RBG1_1C00001G0461	6.321e-26	113.0	COG2143@1|root,COG2143@2|Bacteria	2|Bacteria	O	COG2143 Thioredoxin-related protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH,Thioredoxin_2,Thioredoxin_7
WLSH3_k127_4606185_8	880074.BARVI_08860	1.906e-10	64.0	COG0607@1|root,COG0607@2|Bacteria,4NXGV@976|Bacteroidetes,2FUKK@200643|Bacteroidia,22YWS@171551|Porphyromonadaceae	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4606185_6	1295642.H839_07594	2.371e-25	109.0	COG1765@1|root,COG1765@2|Bacteria,1V7SN@1239|Firmicutes,4HIEM@91061|Bacilli,1WFEG@129337|Geobacillus	91061|Bacilli	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WLSH3_k127_4606185_1	999419.HMPREF1077_01592	4.128e-84	283.0	COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,22WSM@171551|Porphyromonadaceae	976|Bacteroidetes	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH3_k127_4606185_3	161156.JQKW01000008_gene465	8.79e-61	212.0	COG2033@1|root,COG2033@2|Bacteria,2GHU1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Desulfoferrodoxin, N-terminal domain	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
WLSH3_k127_4606185_0	370438.PTH_1417	2.793e-101	338.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,2604F@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH3_k127_4606185_7	373903.Hore_20120	7.161e-19	87.0	COG2221@1|root,COG2221@2|Bacteria	2|Bacteria	C	Nitrite and sulphite reductase 4Fe-4S	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_10,Fer4_6,Flavodoxin_5,HcyBio,PAPS_reduct
WLSH3_k127_4606185_2	880073.Calab_1228	1.755e-67	235.0	COG3634@1|root,COG3634@2|Bacteria,2NPR2@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WLSH3_k127_4606185_9	1121440.AUMA01000009_gene601	2.674e-09	60.0	COG2331@1|root,COG2331@2|Bacteria,1NGC1@1224|Proteobacteria,42W5D@68525|delta/epsilon subdivisions,2WRAY@28221|Deltaproteobacteria,2MD4Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH3_k127_4606185_10	1123388.AQWU01000067_gene657	0.0008264	43.0	2A1R3@1|root,30PZM@2|Bacteria,1WKMT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WLSH3_k127_4613531_0	338966.Ppro_0595	4.928e-76	258.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,43DST@68525|delta/epsilon subdivisions,2WJ4E@28221|Deltaproteobacteria,43TGG@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH-ubiquinone oxidoreductase, chain 49kDa	-	-	1.6.5.3	ko:K00333,ko:K14090	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
WLSH3_k127_4613531_2	926569.ANT_22040	2.891e-20	100.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
WLSH3_k127_4613531_1	338966.Ppro_3526	2.368e-66	229.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WNT3@28221|Deltaproteobacteria,43UYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	ko:K14088	-	-	-	-	ko00000	-	-	-	Oxidored_q6
WLSH3_k127_4613531_4	926569.ANT_22090	1.189e-10	66.0	COG1006@1|root,COG1006@2|Bacteria	2|Bacteria	P	Multisubunit Na H antiporter MnhC subunit	mnhC	-	1.6.5.3	ko:K00340,ko:K05567	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Oxidored_q2
WLSH3_k127_4613531_3	338966.Ppro_3529	5.825e-19	93.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WLSH3_k127_4621694_1	1379698.RBG1_1C00001G1358	4.691e-12	75.0	COG0810@1|root,COG0810@2|Bacteria,2NQ1D@2323|unclassified Bacteria	2|Bacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_C
WLSH3_k127_4621694_0	1379698.RBG1_1C00001G1357	2.397e-19	97.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WLSH3_k127_4621694_3	1379698.RBG1_1C00001G1356	1.299e-08	65.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD1	-	-	-	-	-	-	-	-	-	-	-	ExbD
WLSH3_k127_4621694_2	1379698.RBG1_1C00001G1355	1.114e-10	63.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
WLSH3_k127_4677206_5	266265.Bxe_C1298	3.41e-12	79.0	COG2374@1|root,COG4932@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,1R85W@1224|Proteobacteria,2VWBV@28216|Betaproteobacteria	28216|Betaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
WLSH3_k127_4677206_0	880073.Calab_2380	3.172e-145	469.0	COG1015@1|root,COG1015@2|Bacteria,2NNR5@2323|unclassified Bacteria	2|Bacteria	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iLF82_1304.LF82_0465,iNRG857_1313.NRG857_22165	Metalloenzyme
WLSH3_k127_4677206_3	421531.IX38_06550	4.247e-34	134.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I2SV@117743|Flavobacteriia,3ZS3U@59732|Chryseobacterium	976|Bacteroidetes	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WLSH3_k127_4677206_2	1449126.JQKL01000073_gene3042	1.329e-43	162.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,268ZJ@186813|unclassified Clostridiales	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
WLSH3_k127_4677206_4	1379698.RBG1_1C00001G0980	6.427e-22	98.0	COG1862@1|root,COG1862@2|Bacteria,2NPY3@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase, YajC	yajC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
WLSH3_k127_4677206_1	1379698.RBG1_1C00001G0981	3.267e-44	167.0	COG0242@1|root,COG0242@2|Bacteria,2NPNH@2323|unclassified Bacteria	2|Bacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043021,GO:0043022,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:1901564	3.5.1.88	ko:K01462,ko:K07391	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WLSH3_k127_4694853_2	573413.Spirs_1445	9.852e-16	78.0	28N6F@1|root,2ZBBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4694853_0	316067.Geob_2048	5.741e-107	358.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,43AES@68525|delta/epsilon subdivisions,2X5UI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WLSH3_k127_4694853_1	269797.Mbar_A2953	7.564e-20	96.0	arCOG06802@1|root,arCOG06802@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_469805_0	1379698.RBG1_1C00001G0120	1.65e-133	435.0	28II6@1|root,2Z8JB@2|Bacteria,2NNT1@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_469805_3	693986.MOC_2838	4.279e-05	51.0	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2TRRK@28211|Alphaproteobacteria,1JR1Y@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM Coenzyme A transferase	pct	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WLSH3_k127_469805_1	671143.DAMO_0348	1.086e-88	306.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_469805_2	1379698.RBG1_1C00001G0114	1.287e-25	110.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4755247_0	945543.VIBR0546_07172	2.32e-29	122.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1XUBG@135623|Vibrionales	1236|Gammaproteobacteria	K	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH3_k127_4755247_1	404380.Gbem_3617	1.3e-19	94.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WJ5T@28221|Deltaproteobacteria,43SYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg,dCache_1
WLSH3_k127_4755247_2	591159.ACEZ01000158_gene5591	2.282e-12	79.0	COG1075@1|root,COG1075@2|Bacteria,2I090@201174|Actinobacteria	201174|Actinobacteria	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
WLSH3_k127_477410_3	471855.Shel_08780	2.827e-14	73.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CUEV@84998|Coriobacteriia	84998|Coriobacteriia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WLSH3_k127_477410_1	1232410.KI421421_gene3858	3.484e-101	352.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TBV@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PASTA domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
WLSH3_k127_477410_0	1121468.AUBR01000006_gene359	3.443e-138	461.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,42ETI@68295|Thermoanaerobacterales	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH3_k127_477410_2	667014.Thein_0437	3.675e-17	85.0	COG0770@1|root,COG0770@2|Bacteria,2GH0Z@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH3_k127_479695_0	1191523.MROS_1835	7.504e-267	831.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WLSH3_k127_4844706_0	1191523.MROS_2848	1.174e-155	503.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
WLSH3_k127_4844706_2	1379698.RBG1_1C00001G1026	3.856e-36	144.0	COG0350@1|root,COG0350@2|Bacteria,2NPJ5@2323|unclassified Bacteria	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
WLSH3_k127_4844706_1	555079.Toce_1448	3.309e-82	289.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,42ER0@68295|Thermoanaerobacterales	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WLSH3_k127_4866432_3	518766.Rmar_0505	5.928e-11	70.0	2DSWV@1|root,33HR1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4866432_0	880073.Calab_0318	1.269e-70	263.0	COG0515@1|root,COG0515@2|Bacteria,2NQZR@2323|unclassified Bacteria	880073.Calab_0318|-	KLT	COGs COG0515 Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WLSH3_k127_4866432_2	768706.Desor_4001	2.089e-47	191.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,261ZQ@186807|Peptococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
WLSH3_k127_4866432_1	1120973.AQXL01000088_gene3240	7.42e-55	205.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,279IT@186823|Alicyclobacillaceae	91061|Bacilli	NT	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
WLSH3_k127_4922815_1	1347369.CCAD010000024_gene1506	6.753e-26	121.0	COG2374@1|root,COG3225@1|root,COG4677@1|root,COG2374@2|Bacteria,COG3225@2|Bacteria,COG4677@2|Bacteria,1UJUI@1239|Firmicutes,4I2BS@91061|Bacilli,1ZCHV@1386|Bacillus	91061|Bacilli	N	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,LTD
WLSH3_k127_4922815_2	880073.Calab_3296	6.714e-05	55.0	COG0737@1|root,COG0737@2|Bacteria	2|Bacteria	F	nucleotide catabolic process	-	-	3.4.17.18	ko:K05996	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	5_nucleotid_C,Cytochrome_C554,SBP_bac_8,SLH
WLSH3_k127_4922815_3	926561.KB900617_gene1421	0.0001985	52.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
WLSH3_k127_4922815_0	459349.CLOAM0522	4.917e-80	294.0	COG1555@1|root,COG1555@2|Bacteria,2NQ99@2323|unclassified Bacteria	2|Bacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Cu_amine_oxidN1,HHH_3,SLBB,TraB
WLSH3_k127_4933504_1	13616.ENSMODP00000030429	8.675e-17	91.0	COG0464@1|root,KOG0736@2759|Eukaryota,39HQ2@33154|Opisthokonta,3BAB4@33208|Metazoa,3CUQ8@33213|Bilateria,480BC@7711|Chordata,494VU@7742|Vertebrata,3J7M3@40674|Mammalia,4K4BQ@9263|Metatheria	33208|Metazoa	O	Peroxisomal biogenesis factor 6	PEX6	GO:0000166,GO:0002119,GO:0002164,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005829,GO:0005929,GO:0006605,GO:0006625,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0008022,GO:0008104,GO:0008144,GO:0008150,GO:0009791,GO:0009987,GO:0015031,GO:0015833,GO:0015919,GO:0016020,GO:0016043,GO:0016462,GO:0016558,GO:0016561,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017038,GO:0017076,GO:0017111,GO:0030554,GO:0031090,GO:0031647,GO:0031903,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042579,GO:0042623,GO:0042886,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043574,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0044877,GO:0045184,GO:0046907,GO:0048856,GO:0050821,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0065007,GO:0065008,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:0097159,GO:0097367,GO:0097458,GO:0097730,GO:0097731,GO:0097733,GO:0098588,GO:0098805,GO:0120025,GO:1901265,GO:1901363	-	ko:K02975,ko:K13339	ko03010,ko04146,map03010,map04146	M00177,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko04131	3.A.20.1	-	-	AAA
WLSH3_k127_4933504_0	323097.Nham_3037	3.65e-37	152.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,3JU8X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WLSH3_k127_4934504_6	215803.DB30_8079	2.68e-07	64.0	COG4935@1|root,COG4935@2|Bacteria,1RCIN@1224|Proteobacteria	1224|Proteobacteria	O	Proprotein convertase P-domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,NPCBM_assoc,P_proprotein,Peptidase_M36
WLSH3_k127_4934504_2	756067.MicvaDRAFT_5445	5.695e-48	198.0	COG0810@1|root,COG1404@1|root,COG2931@1|root,COG0810@2|Bacteria,COG1404@2|Bacteria,COG2931@2|Bacteria,1G3AC@1117|Cyanobacteria,1HE4V@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Peptidase C11, clostripain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_C11,VCBS
WLSH3_k127_4934504_4	459349.CLOAM1307	7.646e-27	129.0	COG1361@1|root,COG1361@2|Bacteria,2NRBU@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,FlgD_ig,SdrD_B
WLSH3_k127_4934504_0	1379698.RBG1_1C00001G1314	4.844e-120	398.0	COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WLSH3_k127_4934504_3	1144275.COCOR_02631	1.207e-47	175.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2YVAV@29|Myxococcales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WLSH3_k127_4934504_5	1392487.JIAD01000001_gene1235	4.231e-21	106.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,25UVA@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
WLSH3_k127_4934504_1	1125863.JAFN01000001_gene1365	8.996e-113	377.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	NRDD
WLSH3_k127_4950104_3	459349.CLOAM1266	3.624e-21	100.0	COG0170@1|root,COG0170@2|Bacteria,2NQ5M@2323|unclassified Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	sec59	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WLSH3_k127_4950104_2	1379698.RBG1_1C00001G0462	2.079e-59	218.0	COG2067@1|root,COG2067@2|Bacteria,2NPVZ@2323|unclassified Bacteria	2|Bacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_4950104_4	118173.KB235910_gene4905	6.994e-17	83.0	COG4095@1|root,COG4095@2|Bacteria,1G9AI@1117|Cyanobacteria,1HCTA@1150|Oscillatoriales	1117|Cyanobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
WLSH3_k127_4950104_0	1191523.MROS_1180	1.581e-101	338.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WLSH3_k127_4977839_1	443144.GM21_0968	8.714e-39	149.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria,43TJP@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
WLSH3_k127_4977839_0	1379698.RBG1_1C00001G1646	3.27e-102	345.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
WLSH3_k127_50115_4	1158294.JOMI01000001_gene1404	4.864e-55	202.0	COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WLSH3_k127_50115_1	1121335.Clst_0927	3.239e-139	449.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3WGNI@541000|Ruminococcaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
WLSH3_k127_50115_9	1267535.KB906767_gene5080	5.543e-31	136.0	COG1503@1|root,COG1503@2|Bacteria,3Y6P2@57723|Acidobacteria	57723|Acidobacteria	J	eRF1 domain 3	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach,eRF1_3
WLSH3_k127_50115_8	515635.Dtur_0901	3.513e-31	131.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
WLSH3_k127_50115_0	1191523.MROS_1920	1.326e-186	587.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184	Gp_dh_C,Gp_dh_N
WLSH3_k127_50115_11	1201288.M900_0833	3.425e-16	93.0	COG0737@1|root,COG0737@2|Bacteria,1ND4P@1224|Proteobacteria,42W6F@68525|delta/epsilon subdivisions,2WRWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	Cytochrome_C554
WLSH3_k127_50115_5	511051.CSE_01640	3.154e-52	210.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD,Glutaredoxin,SfLAP
WLSH3_k127_50115_6	290317.Cpha266_0788	4.827e-41	171.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1FEF0@1090|Chlorobi	1090|Chlorobi	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
WLSH3_k127_50115_2	880073.Calab_3114	1.844e-102	340.0	COG2877@1|root,COG2877@2|Bacteria,2NNQB@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the KdsA family	kdsA	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
WLSH3_k127_50115_3	313606.M23134_02417	5.047e-66	241.0	COG5316@1|root,COG5316@2|Bacteria,4NGER@976|Bacteroidetes,47MYA@768503|Cytophagia	976|Bacteroidetes	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
WLSH3_k127_5012201_0	1297617.JPJD01000050_gene1925	2.395e-124	406.0	COG0167@1|root,COG1149@1|root,COG0167@2|Bacteria,COG1149@2|Bacteria,1TRPI@1239|Firmicutes,24A0Z@186801|Clostridia,26BIN@186813|unclassified Clostridiales	186801|Clostridia	F	Dihydroorotate dehydrogenase	-	-	1.3.1.1,1.3.98.1	ko:K00226,ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01867,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4,Fer4_21
WLSH3_k127_5012201_1	1297617.JPJD01000050_gene1929	1.877e-119	397.0	COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,247UH@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TctA
WLSH3_k127_5018129_2	1379698.RBG1_1C00001G1897	1.374e-05	53.0	COG2148@1|root,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WLSH3_k127_5018129_0	1128421.JAGA01000003_gene3429	2.043e-97	333.0	COG0438@1|root,COG0438@2|Bacteria,2NP1P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH3_k127_5018129_1	1379698.RBG1_1C00001G1726	2.623e-25	121.0	29YZ1@1|root,30KVZ@2|Bacteria,2NRNQ@2323|unclassified Bacteria	2|Bacteria	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
WLSH3_k127_5035336_2	323261.Noc_2613	1.168e-20	93.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1WWQB@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
WLSH3_k127_5035336_0	243231.GSU2259	6.51e-83	291.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,43TBC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
WLSH3_k127_5035336_1	323259.Mhun_2469	2.899e-74	258.0	arCOG02322@1|root,arCOG02322@2157|Archaea,2Y48R@28890|Euryarchaeota,2NB1V@224756|Methanomicrobia	2157|Archaea	N	HAMP domain	-	-	2.7.13.3	ko:K03406,ko:K07652	ko02020,ko02030,map02020,map02030	M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,MCPsignal,PAS_9,dCache_3,sCache_3_3
WLSH3_k127_5038096_1	1379698.RBG1_1C00001G1489	3.132e-235	733.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WLSH3_k127_5038096_3	1122917.KB899659_gene5596	5.257e-31	129.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WLSH3_k127_5038096_0	269799.Gmet_0178	7.564e-286	891.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,43UFT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WLSH3_k127_5038096_2	1047013.AQSP01000044_gene247	6.374e-106	370.0	COG3920@1|root,COG3920@2|Bacteria,2NPS5@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2
WLSH3_k127_5046262_0	330214.NIDE0764	1.603e-84	284.0	COG1181@1|root,COG1181@2|Bacteria,3J0JM@40117|Nitrospirae	40117|Nitrospirae	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WLSH3_k127_5046262_4	330214.NIDE0764	2.714e-23	104.0	COG1181@1|root,COG1181@2|Bacteria,3J0JM@40117|Nitrospirae	40117|Nitrospirae	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WLSH3_k127_5046262_1	1499967.BAYZ01000009_gene5334	2.422e-55	219.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,PocR
WLSH3_k127_5046262_3	748449.Halha_0820	5.831e-37	143.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,3WAJ5@53433|Halanaerobiales	186801|Clostridia	K	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_5046262_2	1444309.JAQG01000012_gene2070	3.353e-44	178.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HB1B@91061|Bacilli,26T15@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
WLSH3_k127_5046262_5	313612.L8106_14590	1.923e-06	54.0	COG2730@1|root,COG2931@1|root,COG3386@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
WLSH3_k127_5095297_0	2325.TKV_c00470	1.613e-59	226.0	COG2203@1|root,COG2206@1|root,COG3850@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3850@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,42GDE@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HAMP,HD,HD_5,PAS_9,PocR,Response_reg
WLSH3_k127_5116484_0	517418.Ctha_2470	4.838e-53	190.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,TPR_12,TPR_7,TPR_8
WLSH3_k127_5116484_1	555079.Toce_0227	3.432e-40	154.0	COG3829@1|root,COG3829@2|Bacteria,1VBSS@1239|Firmicutes	1239|Firmicutes	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5116484_3	1340493.JNIF01000003_gene4788	2.478e-11	74.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,3Y6YC@57723|Acidobacteria	57723|Acidobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
WLSH3_k127_5134369_2	1034347.CAHJ01000092_gene1611	0.0001109	46.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5134369_1	1379698.RBG1_1C00001G1142	3.442e-76	266.0	COG0616@1|root,COG0616@2|Bacteria,2NPIE@2323|unclassified Bacteria	2|Bacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
WLSH3_k127_5134369_0	350688.Clos_1521	2.454e-124	406.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,36DRW@31979|Clostridiaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
WLSH3_k127_52008_0	697281.Mahau_0678	3.679e-97	348.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,42F11@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WLSH3_k127_52008_1	1321372.AQQB01000008_gene851	7.168e-75	259.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1WT0K@1307|Streptococcus suis	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS00835	DeoC
WLSH3_k127_5223697_0	1444711.CCJF01000004_gene2285	4.144e-79	267.0	COG1156@1|root,COG1156@2|Bacteria,2JFMM@204428|Chlamydiae	204428|Chlamydiae	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WLSH3_k127_5223697_1	1307761.L21SP2_1880	5.414e-22	103.0	COG1394@1|root,COG1394@2|Bacteria,2J59S@203691|Spirochaetes	203691|Spirochaetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WLSH3_k127_5227995_2	1304874.JAFY01000002_gene357	1.438e-20	93.0	COG0745@1|root,COG0745@2|Bacteria,3TAJR@508458|Synergistetes	508458|Synergistetes	K	PFAM response regulator receiver	-	-	-	ko:K07657,ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_5227995_0	880073.Calab_3536	1.838e-101	336.0	COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WLSH3_k127_5227995_1	1047013.AQSP01000128_gene454	1.713e-30	123.0	COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WLSH3_k127_5238875_0	671143.DAMO_0270	5.893e-142	469.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02021,ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980	ABC_membrane,ABC_tran
WLSH3_k127_5238875_1	1191523.MROS_0141	1.282e-34	147.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	waaC	-	-	ko:K02841,ko:K02843,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WLSH3_k127_5238875_2	1313421.JHBV01000005_gene4611	2.512e-27	118.0	COG2356@1|root,COG2356@2|Bacteria	2|Bacteria	L	deoxyribonuclease I activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CHB_HEX_C_1,Calx-beta,Endonuclease_1,LTD
WLSH3_k127_5240133_2	1379270.AUXF01000005_gene670	3.335e-53	214.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WLSH3_k127_5240133_1	379066.GAU_1407	1.466e-57	207.0	COG1776@1|root,COG1776@2|Bacteria,1ZTIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
WLSH3_k127_5240133_0	1120973.AQXL01000128_gene2834	2.132e-139	465.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,4HAQD@91061|Bacilli,2788Z@186823|Alicyclobacillaceae	91061|Bacilli	T	Signal transducing histidine kinase, homodimeric domain	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
WLSH3_k127_5240133_3	1379270.AUXF01000005_gene667	2.583e-48	175.0	COG2204@1|root,COG2204@2|Bacteria,1ZTMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WLSH3_k127_5372925_1	484019.THA_1392	2.103e-84	284.0	COG4198@1|root,COG4198@2|Bacteria,2GC1X@200918|Thermotogae	200918|Thermotogae	S	PFAM uncharacterised conserved protein UCP033563	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
WLSH3_k127_5372925_0	944479.JQLX01000010_gene519	5.792e-130	428.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2M6FV@213113|Desulfurellales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
WLSH3_k127_5372925_2	880073.Calab_3761	3.194e-62	231.0	COG1462@1|root,COG1462@2|Bacteria,2NQ4P@2323|unclassified Bacteria	2|Bacteria	M	Curli production assembly transport component CsgG	csgG	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF4384,FlgT_C,PG_binding_1
WLSH3_k127_5372925_3	247490.KSU1_C0837	4.199e-19	95.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
WLSH3_k127_5406123_1	671143.DAMO_1541	6.916e-83	281.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
WLSH3_k127_5406123_0	439235.Dalk_2929	1.081e-133	433.0	COG1215@1|root,COG1215@2|Bacteria,1QVA1@1224|Proteobacteria,43BP8@68525|delta/epsilon subdivisions,2X70I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
WLSH3_k127_5423493_0	247490.KSU1_C1112	3.871e-156	504.0	COG0312@1|root,COG0312@2|Bacteria,2J2IZ@203682|Planctomycetes	203682|Planctomycetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
WLSH3_k127_5423493_1	237368.SCABRO_04010	5.685e-38	150.0	COG0312@1|root,COG0312@2|Bacteria,2J2MY@203682|Planctomycetes	203682|Planctomycetes	S	Putative modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
WLSH3_k127_5430046_1	1121423.JONT01000001_gene2059	1.34e-38	153.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WLSH3_k127_5430046_0	591001.Acfer_1302	4.48e-79	277.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4H294@909932|Negativicutes	909932|Negativicutes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WLSH3_k127_5457849_3	338966.Ppro_1950	1.834e-44	163.0	COG1433@1|root,COG1433@2|Bacteria,1MZTM@1224|Proteobacteria,42U2B@68525|delta/epsilon subdivisions,2WQAQ@28221|Deltaproteobacteria,43VJE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WLSH3_k127_5457849_0	517418.Ctha_1656	5.934e-132	423.0	COG0450@1|root,COG0450@2|Bacteria,1FDZ0@1090|Chlorobi	1090|Chlorobi	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
WLSH3_k127_5457849_1	316067.Geob_3554	1.063e-91	325.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
WLSH3_k127_5457849_2	697281.Mahau_0744	1.703e-66	233.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WLSH3_k127_5457849_4	1382306.JNIM01000001_gene4122	5.955e-17	82.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
WLSH3_k127_5462640_2	1191523.MROS_0398	2.071e-19	94.0	COG3088@1|root,COG3088@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564	-	ko:K02198,ko:K02200,ko:K04016,ko:K04017,ko:K04018	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmH
WLSH3_k127_5462640_0	880073.Calab_2474	3.713e-89	304.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
WLSH3_k127_5462640_1	177437.HRM2_29490	8.121e-72	265.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
WLSH3_k127_5483412_0	536232.CLM_0436	3.705e-33	141.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,36F8C@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
WLSH3_k127_5514168_1	518766.Rmar_1876	1.056e-39	162.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1FIVK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WLSH3_k127_5514168_0	880073.Calab_3593	1.698e-48	179.0	COG1403@1|root,COG1403@2|Bacteria,2NPJD@2323|unclassified Bacteria	2|Bacteria	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_4,HNH_5
WLSH3_k127_5514168_2	1121904.ARBP01000001_gene5713	5.986e-34	138.0	2E1HF@1|root,32WVJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3996
WLSH3_k127_5514168_3	1278073.MYSTI_06490	8.568e-09	62.0	COG5373@1|root,COG5373@2|Bacteria,1NGHT@1224|Proteobacteria,434ZS@68525|delta/epsilon subdivisions,2WZAM@28221|Deltaproteobacteria,2Z1QB@29|Myxococcales	28221|Deltaproteobacteria	N	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5516411_0	436308.Nmar_1177	1.217e-116	394.0	COG1164@1|root,arCOG04758@2157|Archaea,41S7J@651137|Thaumarchaeota	651137|Thaumarchaeota	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WLSH3_k127_5528818_1	246969.TAM4_913	1.553e-09	68.0	COG4945@1|root,arCOG02559@1|root,arCOG03264@1|root,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG03771@2157|Archaea,2XSTV@28890|Euryarchaeota,243KF@183968|Thermococci	183968|Thermococci	G	C-terminal binding-module, SLH-like, of glucodextranase	-	-	-	-	-	-	-	-	-	-	-	-	Glucodextran_C,PEGA
WLSH3_k127_5528818_2	292563.Cyast_0845	3.861e-05	55.0	COG1462@1|root,COG1462@2|Bacteria,1G2XT@1117|Cyanobacteria	1117|Cyanobacteria	M	protein involved in formation of curli polymers	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
WLSH3_k127_5528818_0	448385.sce5134	5.432e-267	840.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42Z54@68525|delta/epsilon subdivisions,2WUB9@28221|Deltaproteobacteria,2YYC4@29|Myxococcales	28221|Deltaproteobacteria	J	Anticodon-binding domain of tRNA	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WLSH3_k127_5547931_0	1379698.RBG1_1C00001G0435	6.959e-127	451.0	COG1747@1|root,COG1747@2|Bacteria,2NP33@2323|unclassified Bacteria	2|Bacteria	M	methyltransferase	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N,SprA_N
WLSH3_k127_5662746_1	1265505.ATUG01000003_gene849	4.148e-09	57.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,42ND4@68525|delta/epsilon subdivisions,2WKQP@28221|Deltaproteobacteria,2MMYU@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WLSH3_k127_5662746_0	1123508.JH636440_gene2098	6.351e-155	506.0	COG0138@1|root,COG0138@2|Bacteria,2IXB5@203682|Planctomycetes	203682|Planctomycetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WLSH3_k127_5692302_1	768670.Calni_0229	1.277e-06	58.0	COG0457@1|root,COG0457@2|Bacteria,2GFR1@200930|Deferribacteres	200930|Deferribacteres	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
WLSH3_k127_5692302_0	379066.GAU_1412	1.242e-25	120.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
WLSH3_k127_571964_2	338966.Ppro_0388	2.633e-13	70.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,43UUC@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WLSH3_k127_571964_0	1183377.Py04_0198	7.888e-95	319.0	COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci	183968|Thermococci	E	GTPase activity	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
WLSH3_k127_571964_1	65093.PCC7418_3103	7.101e-19	92.0	COG0668@1|root,COG0668@2|Bacteria,1G08V@1117|Cyanobacteria	1117|Cyanobacteria	M	mechanosensitive ion channel	mscS	-	-	-	-	-	-	-	-	-	-	-	MS_channel
WLSH3_k127_5740294_0	588581.Cpap_0931	3.987e-80	274.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3WGPD@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WLSH3_k127_5740294_3	760568.Desku_3208	9.405e-20	106.0	COG3322@1|root,COG3437@1|root,COG3322@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,25F8N@186801|Clostridia,2610P@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM PAS domain S-box	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GGDEF,HD_5,PAS_3,PAS_4
WLSH3_k127_5740294_2	240292.Ava_2710	1.729e-25	125.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1HRHF@1161|Nostocales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_9
WLSH3_k127_5740294_1	1173027.Mic7113_4789	4.66e-61	243.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9
WLSH3_k127_5757467_0	309799.DICTH_0368	4.725e-63	228.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_5
WLSH3_k127_5757467_1	373903.Hore_15950	5.251e-61	216.0	COG0778@1|root,COG0778@2|Bacteria,1V49Q@1239|Firmicutes,24IH8@186801|Clostridia	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_5757467_2	452637.Oter_4143	2.242e-05	48.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WLSH3_k127_5760257_3	1047013.AQSP01000138_gene1077	9.683e-21	100.0	COG1538@1|root,COG1538@2|Bacteria,2NPKK@2323|unclassified Bacteria	2|Bacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WLSH3_k127_5760257_4	401526.TcarDRAFT_2710	2.783e-18	93.0	COG1309@1|root,COG1309@2|Bacteria,1V3CI@1239|Firmicutes,4H43E@909932|Negativicutes	909932|Negativicutes	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH3_k127_5760257_2	1123376.AUIU01000011_gene1054	1.441e-47	183.0	COG1463@1|root,COG1463@2|Bacteria,3J164@40117|Nitrospirae	40117|Nitrospirae	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WLSH3_k127_5760257_0	1379698.RBG1_1C00001G0979	2.742e-74	257.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	mkl	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WLSH3_k127_5760257_1	861299.J421_3477	1.121e-58	212.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WLSH3_k127_5760257_5	1120985.AUMI01000011_gene397	2.568e-06	59.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Phenol_MetA_deg
WLSH3_k127_5770539_1	204669.Acid345_3014	1.123e-44	175.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WLSH3_k127_5770539_0	1157490.EL26_02245	5.91e-70	249.0	COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli	91061|Bacilli	S	homoserine kinase type II (protein kinase fold)	yerI	-	-	-	-	-	-	-	-	-	-	-	APH
WLSH3_k127_5770539_3	1122614.JHZF01000017_gene2780	1.938e-12	68.0	COG1024@1|root,COG1024@2|Bacteria,1PSRK@1224|Proteobacteria,2U22I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WLSH3_k127_5790958_2	926561.KB900617_gene1765	1.082e-35	143.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia,3WBT4@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
WLSH3_k127_5790958_1	316067.Geob_3095	1.735e-48	183.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42QX1@68525|delta/epsilon subdivisions,2WMNH@28221|Deltaproteobacteria,43TQD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
WLSH3_k127_5790958_0	880073.Calab_3589	1.553e-49	184.0	COG1386@1|root,COG1386@2|Bacteria,2NPPM@2323|unclassified Bacteria	2|Bacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WLSH3_k127_5904221_0	903818.KI912268_gene3321	2.35e-199	627.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WLSH3_k127_5904221_2	357808.RoseRS_2140	3.172e-23	112.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
WLSH3_k127_5904221_3	246197.MXAN_4740	1.805e-15	90.0	COG0457@1|root,COG0457@2|Bacteria,1P92T@1224|Proteobacteria,4331J@68525|delta/epsilon subdivisions,2WYEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5904221_1	1121430.JMLG01000002_gene1035	2.841e-51	190.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WLSH3_k127_5904221_4	90814.KL370891_gene780	1.351e-13	73.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_5910364_1	1121413.JMKT01000008_gene1463	2.143e-09	63.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2MBWU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WLSH3_k127_5910364_0	717231.Flexsi_1493	3.963e-10	63.0	COG0071@1|root,COG0071@2|Bacteria,2GFTF@200930|Deferribacteres	200930|Deferribacteres	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH3_k127_5922028_0	1121121.KB894305_gene3685	1.288e-49	183.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
WLSH3_k127_5922028_1	337191.KTR9_3209	3.977e-36	143.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4GAT1@85026|Gordoniaceae	201174|Actinobacteria	U	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WLSH3_k127_5929885_0	760568.Desku_1299	8.778e-223	715.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,25ZY7@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WLSH3_k127_5929885_7	318464.IO99_02700	9.844e-29	122.0	COG3981@1|root,COG3981@2|Bacteria,1VBAS@1239|Firmicutes,24IT8@186801|Clostridia,36ISC@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH3_k127_5929885_5	439235.Dalk_2598	4.399e-34	141.0	COG0716@1|root,COG1146@1|root,COG0716@2|Bacteria,COG1146@2|Bacteria,1NFA5@1224|Proteobacteria,42WN8@68525|delta/epsilon subdivisions,2WRNS@28221|Deltaproteobacteria,2MNUP@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Flavodoxin_5
WLSH3_k127_5929885_3	926692.AZYG01000084_gene634	1.728e-98	333.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,24BAN@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WLSH3_k127_5929885_4	555079.Toce_1165	6.439e-98	331.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,42F7B@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM peptidase M42 family protein	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
WLSH3_k127_5929885_8	483219.LILAB_02975	1.626e-21	99.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	frgC	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH3_k127_5929885_2	555088.DealDRAFT_2007	8.895e-107	356.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	celM	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
WLSH3_k127_5929885_6	1321786.HMPREF1992_01482	1.808e-32	136.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,4H4HE@909932|Negativicutes	909932|Negativicutes	M	Peptidase, M23 family	envC_2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH3_k127_5929885_1	272562.CA_C0001	9.705e-133	436.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,36DSQ@31979|Clostridiaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WLSH3_k127_5936646_0	1382306.JNIM01000001_gene1372	2.351e-89	311.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cytoplasmic peptidoglycan synthetase domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH3_k127_5936646_1	1379270.AUXF01000005_gene669	8.739e-22	104.0	COG1776@1|root,COG1776@2|Bacteria,1ZTIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
WLSH3_k127_5937161_2	391612.CY0110_10042	1.449e-28	122.0	COG0577@1|root,COG0577@2|Bacteria,1GCGB@1117|Cyanobacteria,3KFQE@43988|Cyanothece	1117|Cyanobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WLSH3_k127_5937161_1	1191523.MROS_2282	8.736e-90	301.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_5937161_0	1379698.RBG1_1C00001G1364	6.393e-94	323.0	COG0845@1|root,COG0845@2|Bacteria,2NP97@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
WLSH3_k127_5937161_3	1127695.HMPREF9163_01604	9.61e-19	97.0	COG1538@1|root,COG1538@2|Bacteria,1TQ0W@1239|Firmicutes,4H3MR@909932|Negativicutes	909932|Negativicutes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WLSH3_k127_5943192_0	1449126.JQKL01000075_gene1	3.503e-222	700.0	COG4147@1|root,COG4147@2|Bacteria,1UHT5@1239|Firmicutes,24G6E@186801|Clostridia	186801|Clostridia	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
WLSH3_k127_5943192_2	1449126.JQKL01000075_gene2	2.977e-18	89.0	2DQ0U@1|root,3349F@2|Bacteria	2|Bacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
WLSH3_k127_5950029_0	944479.JQLX01000011_gene928	2.521e-161	516.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2M6TU@213113|Desulfurellales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	bioF1	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_5950029_1	926549.KI421517_gene356	1.038e-105	352.0	COG0685@1|root,COG0685@2|Bacteria,4NDY0@976|Bacteroidetes,47KQ7@768503|Cytophagia	976|Bacteroidetes	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
WLSH3_k127_5950029_2	1385935.N836_08870	1.848e-52	190.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1G0PS@1117|Cyanobacteria,1H8PE@1150|Oscillatoriales	1117|Cyanobacteria	E	Vitamin B12 dependent methionine synthase, activation domain	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WLSH3_k127_5971553_1	580340.Tlie_1075	1.507e-39	151.0	COG2109@1|root,COG2109@2|Bacteria,3TB75@508458|Synergistetes	508458|Synergistetes	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
WLSH3_k127_5971553_0	1519464.HY22_12570	2.112e-47	191.0	COG4288@1|root,COG4288@2|Bacteria,1FE3D@1090|Chlorobi	1090|Chlorobi	S	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,LTD
WLSH3_k127_5979095_0	269798.CHU_0569	1.36e-59	228.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,47MTB@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
WLSH3_k127_5979095_1	945713.IALB_2064	5.816e-09	67.0	COG0457@1|root,COG0457@2|Bacteria	945713.IALB_2064|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6042990_3	880073.Calab_2485	2.663e-14	86.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Fn3-like,Glyco_hydro_3_C,SLH
WLSH3_k127_6042990_1	880073.Calab_3104	5.031e-59	226.0	COG2356@1|root,COG4447@1|root,COG2356@2|Bacteria,COG4447@2|Bacteria,2NRJS@2323|unclassified Bacteria	2|Bacteria	L	Endonuclease I	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Endonuclease_1,FlgD_ig,LTD,PSII_BNR
WLSH3_k127_6042990_0	1382359.JIAL01000001_gene1189	3.418e-143	477.0	COG0488@1|root,COG0488@2|Bacteria,3Y340@57723|Acidobacteria,2JI2P@204432|Acidobacteriia	204432|Acidobacteriia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
WLSH3_k127_6042990_2	485913.Krac_12580	7.282e-25	109.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WLSH3_k127_6044445_0	1499967.BAYZ01000076_gene842	2.856e-60	229.0	COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
WLSH3_k127_6044445_1	1064535.MELS_1248	1.001e-17	94.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,4H227@909932|Negativicutes	909932|Negativicutes	D	SpoIID LytB domain protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
WLSH3_k127_6063491_1	555079.Toce_1591	8.16e-160	514.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia,42FRS@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM UDP-glucose GDP-mannose dehydrogenase	wbpA1	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K02474,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WLSH3_k127_6063491_2	192952.MM_1167	7.425e-135	437.0	COG1088@1|root,arCOG01371@2157|Archaea,2XUZX@28890|Euryarchaeota,2N94H@224756|Methanomicrobia	224756|Methanomicrobia	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WLSH3_k127_6063491_4	1047013.AQSP01000144_gene875	1.548e-71	244.0	COG1898@1|root,COG1898@2|Bacteria,2NP7U@2323|unclassified Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
WLSH3_k127_6063491_3	1033743.CAES01000018_gene2556	1.882e-78	273.0	COG1089@1|root,COG1089@2|Bacteria,1UJFF@1239|Firmicutes,4HF5Y@91061|Bacilli,275YJ@186822|Paenibacillaceae	91061|Bacilli	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WLSH3_k127_6063491_0	525904.Tter_1711	1.419e-163	518.0	COG1089@1|root,COG1089@2|Bacteria,2NNM2@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WLSH3_k127_6063883_1	667014.Thein_1636	5.595e-96	328.0	COG1022@1|root,COG1022@2|Bacteria,2GIQW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WLSH3_k127_6063883_2	637390.AFOH01000096_gene277	5.013e-53	194.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,2NCI6@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WLSH3_k127_6063883_0	398767.Glov_2714	5.755e-113	376.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
WLSH3_k127_6063883_3	1048983.EL17_15565	0.0009153	44.0	COG1216@1|root,COG1216@2|Bacteria,4NGEQ@976|Bacteroidetes,47JZ6@768503|Cytophagia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH3_k127_6067791_0	1304880.JAGB01000001_gene514	6.439e-43	163.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
WLSH3_k127_6067791_1	880073.Calab_3701	3.97e-14	75.0	COG3027@1|root,COG3027@2|Bacteria,2NQ5R@2323|unclassified Bacteria	2|Bacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
WLSH3_k127_6067791_2	1121324.CLIT_11c02480	4.11e-13	72.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25R0R@186804|Peptostreptococcaceae	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WLSH3_k127_6087661_2	866774.HMPREF9248_0110	8.774e-06	49.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CUGN@84998|Coriobacteriia	84998|Coriobacteriia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
WLSH3_k127_6087661_1	857293.CAAU_2205	8.938e-125	409.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,36DUG@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	degT1	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WLSH3_k127_6087661_0	555079.Toce_1427	1.183e-141	465.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
WLSH3_k127_6097278_1	1027292.HMPREF9372_3593	2.473e-49	182.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,26DEV@186818|Planococcaceae	91061|Bacilli	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WLSH3_k127_6097278_0	318464.IO99_15200	7.662e-50	193.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes	1239|Firmicutes	S	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WLSH3_k127_6116812_1	1382306.JNIM01000001_gene725	1.212e-63	229.0	COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WLSH3_k127_6116812_0	1121440.AUMA01000005_gene2581	1.261e-89	312.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
WLSH3_k127_6116812_2	1449126.JQKL01000006_gene737	1.681e-45	179.0	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,26BAW@186813|unclassified Clostridiales	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
WLSH3_k127_6116812_3	237368.SCABRO_01360	2.34e-12	69.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
WLSH3_k127_6140553_1	215803.DB30_5113	1.214e-43	167.0	COG0793@1|root,COG0793@2|Bacteria,1RGID@1224|Proteobacteria,4382G@68525|delta/epsilon subdivisions,2X3CI@28221|Deltaproteobacteria,2YVET@29|Myxococcales	28221|Deltaproteobacteria	M	tail specific protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
WLSH3_k127_6140553_0	945713.IALB_3151	2.626e-89	317.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,CBM9_1
WLSH3_k127_6150541_2	756499.Desde_3856	9.463e-13	78.0	COG3307@1|root,COG3307@2|Bacteria,1V152@1239|Firmicutes,24FCJ@186801|Clostridia,2613Y@186807|Peptococcaceae	186801|Clostridia	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WLSH3_k127_6150541_0	1408433.JHXV01000024_gene1490	3.601e-64	233.0	COG0438@1|root,COG0438@2|Bacteria,4NU4C@976|Bacteroidetes,1I610@117743|Flavobacteriia,2PC3C@246874|Cryomorphaceae	976|Bacteroidetes	M	Glycosyl transferase 4-like	remC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
WLSH3_k127_6150541_1	1121091.AUMP01000008_gene3582	2.48e-23	107.0	COG0438@1|root,COG0438@2|Bacteria,1UYBT@1239|Firmicutes,4HCSK@91061|Bacilli	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
WLSH3_k127_6178421_1	760568.Desku_1313	1.158e-63	225.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,260EN@186807|Peptococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WLSH3_k127_6178421_4	489825.LYNGBM3L_22570	3.929e-36	149.0	COG0392@1|root,COG0392@2|Bacteria,1G41A@1117|Cyanobacteria,1HD8Q@1150|Oscillatoriales	1117|Cyanobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WLSH3_k127_6178421_0	880073.Calab_1384	2.938e-92	319.0	COG1216@1|root,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria	2|Bacteria	L	Glycosyltransferase like family 2	wbbL_2	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
WLSH3_k127_6178421_3	880073.Calab_0215	1.288e-60	220.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WLSH3_k127_6178421_5	246197.MXAN_4761	5.068e-31	126.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2YVKR@29|Myxococcales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WLSH3_k127_6178421_2	1191523.MROS_1962	1.36e-63	222.0	COG0054@1|root,COG0054@2|Bacteria	2|Bacteria	H	6,7-dimethyl-8-ribityllumazine synthase activity	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1825,iSB619.SA_RS08940,iSFV_1184.SFV_0380	DMRL_synthase
WLSH3_k127_6181104_0	1379698.RBG1_1C00001G0503	1.304e-67	252.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
WLSH3_k127_6228968_1	1379698.RBG1_1C00001G1788	2.344e-54	210.0	COG2067@1|root,COG3292@1|root,COG2067@2|Bacteria,COG3292@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Reg_prop,Reprolysin_5,VCBS
WLSH3_k127_6228968_0	1379698.RBG1_1C00001G1787	5.593e-101	366.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria,2NPRE@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
WLSH3_k127_6230730_0	349161.Dred_2506	9.907e-18	93.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,260KF@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WLSH3_k127_6230730_1	1379698.RBG1_1C00001G0428	3.035e-14	84.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,2NREM@2323|unclassified Bacteria	2|Bacteria	O	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	B_lectin,FlgD_ig,PQQ_2,PQQ_3,Pkinase,VCBS
WLSH3_k127_6230730_2	926550.CLDAP_27060	1.551e-06	60.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20,fn3
WLSH3_k127_6238430_0	880073.Calab_3754	7.451e-80	299.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6238430_1	1121013.P873_09695	2.424e-13	82.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,1X527@135614|Xanthomonadales	135614|Xanthomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WLSH3_k127_6296896_1	945713.IALB_0946	3.235e-73	256.0	COG0568@1|root,COG0568@2|Bacteria	2|Bacteria	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WLSH3_k127_6296896_0	1379698.RBG1_1C00001G0597	3.708e-115	388.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WLSH3_k127_6296896_3	1122138.AQUZ01000031_gene4216	2.914e-19	90.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,4DRJ1@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
WLSH3_k127_6296896_2	671143.DAMO_2768	8.42e-35	138.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WLSH3_k127_6333357_0	1122919.KB905582_gene3720	1.122e-70	244.0	COG0388@1|root,COG0388@2|Bacteria,1U2RZ@1239|Firmicutes,4ICEP@91061|Bacilli,272G5@186822|Paenibacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
WLSH3_k127_6333357_2	1121373.KB903623_gene2282	6.666e-13	81.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,47JGQ@768503|Cytophagia	976|Bacteroidetes	E	PFAM Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
WLSH3_k127_6333357_1	755732.Fluta_0380	3.146e-68	245.0	COG0308@1|root,COG0308@2|Bacteria,4NEXH@976|Bacteroidetes,1HYBR@117743|Flavobacteriia,2PAP0@246874|Cryomorphaceae	976|Bacteroidetes	E	peptidase M1	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M1
WLSH3_k127_6337623_11	1340493.JNIF01000004_gene1003	1.081e-08	57.0	COG0503@1|root,COG0503@2|Bacteria,3Y30R@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WLSH3_k127_6337623_0	880073.Calab_2700	1.322e-198	652.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NNRF@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,2.C.1.2	-	-	Bac_surface_Ag,PD40,POTRA,Peptidase_MA_2
WLSH3_k127_6337623_9	935948.KE386495_gene1786	7.442e-35	141.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,42GVS@68295|Thermoanaerobacterales	186801|Clostridia	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
WLSH3_k127_6337623_7	882.DVU_1532	1.098e-55	199.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2MBFU@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WLSH3_k127_6337623_2	1232410.KI421412_gene394	1.355e-107	357.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,43S7S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	GTP1/OBG	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
WLSH3_k127_6337623_12	1499967.BAYZ01000103_gene3749	0.0004705	50.0	COG1262@1|root,COG1413@1|root,COG1262@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	MA20_14850	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,HEAT_2,HEAT_PBS
WLSH3_k127_6337623_4	1379698.RBG1_1C00001G1623	1.533e-87	302.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
WLSH3_k127_6337623_8	269799.Gmet_0043	3.398e-48	184.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,4304I@68525|delta/epsilon subdivisions,2WVDN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	sensor histidine kinase response	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HATPase_c,HisKA,Response_reg
WLSH3_k127_6337623_1	868131.MSWAN_0651	5.857e-137	445.0	COG2006@1|root,arCOG02447@2157|Archaea,2XW1U@28890|Euryarchaeota	28890|Euryarchaeota	C	4Fe-4S ferredoxin iron-sulfur binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_7
WLSH3_k127_6337623_6	1379698.RBG1_1C00001G1514	3.636e-62	226.0	COG1560@1|root,COG1560@2|Bacteria,2NPD7@2323|unclassified Bacteria	2|Bacteria	M	Lipid A biosynthesis	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
WLSH3_k127_6337623_3	1379698.RBG1_1C00001G1139	3.379e-103	353.0	COG0323@1|root,COG0323@2|Bacteria,2NNP7@2323|unclassified Bacteria	2|Bacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WLSH3_k127_6337623_10	331678.Cphamn1_0302	5.013e-17	81.0	COG0323@1|root,COG0323@2|Bacteria,1FDFS@1090|Chlorobi	1090|Chlorobi	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WLSH3_k127_6337623_5	880073.Calab_3295	6.637e-72	254.0	COG0324@1|root,COG0324@2|Bacteria,2NP6D@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WLSH3_k127_6338107_2	861299.J421_0157	9.552e-41	156.0	COG1871@1|root,COG1871@2|Bacteria,1ZTR7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
WLSH3_k127_6338107_1	379066.GAU_0364	2.323e-41	157.0	COG0745@1|root,COG0745@2|Bacteria,1ZTZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WLSH3_k127_6338107_3	861299.J421_0155	1.068e-15	83.0	COG1406@1|root,COG1406@2|Bacteria,1ZU7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
WLSH3_k127_6338107_0	1379270.AUXF01000002_gene1698	2.237e-45	171.0	COG2201@1|root,COG2201@2|Bacteria,1ZTC0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WLSH3_k127_6350180_0	518766.Rmar_2754	7.079e-136	456.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1FIP1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WLSH3_k127_6375214_6	32057.KB217483_gene9032	4.154e-06	56.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1HIJM@1161|Nostocales	1117|Cyanobacteria	S	SPTR Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
WLSH3_k127_6375214_2	574087.Acear_0004	1.324e-70	252.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3WA8H@53433|Halanaerobiales	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WLSH3_k127_6375214_3	926550.CLDAP_22130	5.23e-61	214.0	COG1051@1|root,COG1051@2|Bacteria,2G7HA@200795|Chloroflexi	200795|Chloroflexi	F	PFAM NUDIX hydrolase	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WLSH3_k127_6375214_4	1321778.HMPREF1982_02374	6.91e-33	138.0	COG2820@1|root,COG2820@2|Bacteria,1UFD2@1239|Firmicutes,24ICS@186801|Clostridia	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
WLSH3_k127_6375214_5	1540221.JQNI01000002_gene1644	1.549e-08	61.0	COG5512@1|root,COG5512@2|Bacteria,1WIYS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
WLSH3_k127_6375214_0	635013.TherJR_0008	7.29e-285	888.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,260WQ@186807|Peptococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WLSH3_k127_6375214_1	1191523.MROS_1041	1.249e-113	371.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WLSH3_k127_6381234_3	509191.AEDB02000089_gene3184	2.452e-27	111.0	COG1233@1|root,COG1233@2|Bacteria,1TS4A@1239|Firmicutes,249K1@186801|Clostridia,3WJAW@541000|Ruminococcaceae	186801|Clostridia	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WLSH3_k127_6381234_4	517418.Ctha_1726	2.749e-22	110.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,TPR_12,TPR_7,TPR_8
WLSH3_k127_6381234_1	1121362.A605_12770	1.824e-45	168.0	arCOG05276@1|root,3195F@2|Bacteria,2IM15@201174|Actinobacteria,22NR3@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6381234_2	477974.Daud_0922	1.359e-34	138.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,2629C@186807|Peptococcaceae	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
WLSH3_k127_6381234_0	1379698.RBG1_1C00001G1152	1.049e-86	295.0	COG0195@1|root,COG0195@2|Bacteria,2NNV1@2323|unclassified Bacteria	2|Bacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
WLSH3_k127_6384536_0	459349.CLOAM0429	1.248e-79	298.0	COG1572@1|root,COG1572@2|Bacteria,2NQER@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig,Peptidase_C25,Propeptide_C25
WLSH3_k127_6384536_1	459349.CLOAM1690	1.344e-10	63.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
WLSH3_k127_6389423_1	1121423.JONT01000003_gene985	1.1e-35	146.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,261SY@186807|Peptococcaceae	186801|Clostridia	S	PFAM Phosphoribosyl transferase domain	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
WLSH3_k127_6389423_0	1002367.HMPREF0673_02764	1.483e-52	190.0	COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WLSH3_k127_6439724_6	1541959.KQ51_00260	7.55e-05	52.0	2E6H4@1|root,3314B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6439724_3	1286171.EAL2_808p06620	5.009e-38	151.0	28JAU@1|root,2ZYJS@2|Bacteria,1UPNS@1239|Firmicutes,25HK7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6439724_0	944481.JAFP01000001_gene875	6.297e-153	497.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2M6I9@213113|Desulfurellales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
WLSH3_k127_6439724_5	1532557.JL37_03870	3.587e-30	125.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,3T4GB@506|Alcaligenaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
WLSH3_k127_6439724_1	459349.CLOAM0239	1.136e-134	451.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	BACON,Peptidase_M6
WLSH3_k127_6439724_4	1131269.AQVV01000011_gene2542	3.672e-34	138.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	-	2.1.1.63	ko:K00567,ko:K13531	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
WLSH3_k127_6439724_2	1395513.P343_00015	7.989e-44	182.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
WLSH3_k127_6443586_1	933262.AXAM01000002_gene536	6.365e-57	201.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2MIPN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
WLSH3_k127_6443586_0	933262.AXAM01000002_gene535	5.028e-105	352.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42M3U@68525|delta/epsilon subdivisions,2WJQ6@28221|Deltaproteobacteria,2MHKZ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Biotin and Thiamin Synthesis associated	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
WLSH3_k127_6454413_3	1395587.P364_0115600	1.006e-31	130.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli,26R06@186822|Paenibacillaceae	91061|Bacilli	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WLSH3_k127_6454413_1	370438.PTH_1863	5.818e-99	351.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,260PC@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WLSH3_k127_6454413_0	414684.RC1_0616	5.075e-123	404.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2JQ3T@204441|Rhodospirillales	204441|Rhodospirillales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WLSH3_k127_6454413_2	644966.Tmar_0866	2.519e-73	259.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WCHQ@538999|Clostridiales incertae sedis	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WLSH3_k127_6457339_0	485916.Dtox_0989	1.323e-78	273.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,261WJ@186807|Peptococcaceae	186801|Clostridia	S	conserved protein (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
WLSH3_k127_6457339_2	1047013.AQSP01000130_gene1849	3.473e-76	264.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	pdxH	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
WLSH3_k127_6457339_3	386456.JQKN01000007_gene3371	1.097e-13	80.0	arCOG05048@1|root,arCOG05048@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
WLSH3_k127_6457339_1	264732.Moth_1000	1.637e-78	270.0	COG0477@1|root,COG2814@2|Bacteria,1TRUT@1239|Firmicutes,25E84@186801|Clostridia,42FN6@68295|Thermoanaerobacterales	186801|Clostridia	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WLSH3_k127_6485054_2	1379698.RBG1_1C00001G1726	4.328e-34	148.0	29YZ1@1|root,30KVZ@2|Bacteria,2NRNQ@2323|unclassified Bacteria	2|Bacteria	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
WLSH3_k127_6485054_3	585425.KR52_06270	1.252e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,1GISU@1117|Cyanobacteria,1H0H1@1129|Synechococcus	1117|Cyanobacteria	H	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31,TPR_1,TPR_11,TPR_8
WLSH3_k127_6485054_1	497964.CfE428DRAFT_3304	1.835e-70	247.0	COG1212@1|root,COG1212@2|Bacteria,46SS4@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
WLSH3_k127_6485054_0	1120973.AQXL01000133_gene1815	3.062e-216	682.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,4HAKG@91061|Bacilli,277V5@186823|Alicyclobacillaceae	91061|Bacilli	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0000166,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09060,iYO844.BSU30560	PEPCK_ATP
WLSH3_k127_6485074_2	517417.Cpar_1790	2.635e-39	154.0	COG0196@1|root,COG0196@2|Bacteria,1FDJE@1090|Chlorobi	1090|Chlorobi	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WLSH3_k127_6485074_3	760568.Desku_2536	2.584e-33	132.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,262DU@186807|Peptococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WLSH3_k127_6485074_0	1379698.RBG1_1C00001G1160	1.406e-255	806.0	COG1185@1|root,COG1185@2|Bacteria,2NNX7@2323|unclassified Bacteria	2|Bacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WLSH3_k127_6485074_4	997884.HMPREF1068_00362	4.582e-12	76.0	COG1361@1|root,COG1520@1|root,COG4870@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG4870@2|Bacteria,4NVQ3@976|Bacteroidetes,2G321@200643|Bacteroidia,4ATRZ@815|Bacteroidaceae	976|Bacteroidetes	MO	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
WLSH3_k127_6485074_1	204669.Acid345_4043	3.564e-111	374.0	COG1680@1|root,COG1680@2|Bacteria,3Y7SG@57723|Acidobacteria,2JMWV@204432|Acidobacteriia	204432|Acidobacteriia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WLSH3_k127_6485074_5	555779.Dthio_PD2839	0.0003987	44.0	2C6B2@1|root,335GA@2|Bacteria,1NG8G@1224|Proteobacteria,42X8T@68525|delta/epsilon subdivisions,2WSSY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6517967_1	671143.DAMO_2843	1.091e-09	66.0	2DGXT@1|root,2ZXPG@2|Bacteria,2NRPI@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6517967_2	1382359.JIAL01000001_gene792	1.982e-07	60.0	COG3678@1|root,COG3678@2|Bacteria,3Y5A6@57723|Acidobacteria,2JJQD@204432|Acidobacteriia	204432|Acidobacteriia	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
WLSH3_k127_6517967_0	1242864.D187_007635	3.333e-80	295.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4Y@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH3_k127_6517967_3	589865.DaAHT2_2282	4.597e-07	58.0	COG4970@1|root,COG4970@2|Bacteria,1Q0DU@1224|Proteobacteria,42W7A@68525|delta/epsilon subdivisions,2WS6U@28221|Deltaproteobacteria,2MKVN@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
WLSH3_k127_6517967_4	1209072.ALBT01000033_gene1723	5.363e-05	55.0	COG4966@1|root,COG4966@2|Bacteria,1R5YK@1224|Proteobacteria,1RZIZ@1236|Gammaproteobacteria,1FHH9@10|Cellvibrio	1236|Gammaproteobacteria	NU	Type IV Pilus-assembly protein W	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
WLSH3_k127_6531782_0	1343739.PAP_06720	6.984e-35	154.0	arCOG01312@1|root,arCOG03256@1|root,arCOG03499@1|root,arCOG01312@2157|Archaea,arCOG03256@2157|Archaea,arCOG03499@2157|Archaea,2Y7MH@28890|Euryarchaeota,243S6@183968|Thermococci	183968|Thermococci	L	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
WLSH3_k127_6531782_1	1121896.JMLU01000001_gene1198	1.542e-19	104.0	COG2356@1|root,COG2356@2|Bacteria,4PNZR@976|Bacteroidetes	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
WLSH3_k127_656516_5	222534.KB893739_gene1440	2.198e-06	52.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4ESU5@85013|Frankiales	201174|Actinobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WLSH3_k127_656516_4	1384056.N787_01905	1.205e-10	72.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,1RP9Q@1236|Gammaproteobacteria,1X2Y3@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
WLSH3_k127_656516_0	880073.Calab_2442	2.373e-204	672.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WLSH3_k127_656516_2	588581.Cpap_2334	8.559e-84	287.0	COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,25B2N@186801|Clostridia,3WI5F@541000|Ruminococcaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
WLSH3_k127_656516_1	768704.Desmer_0485	4.343e-85	294.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,261AJ@186807|Peptococcaceae	186801|Clostridia	U	ABC-type Mn2 Zn2 transport system, permease component	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
WLSH3_k127_656516_3	55529.EKX49760	4.853e-13	79.0	KOG1703@1|root,KOG1703@2759|Eukaryota	2759|Eukaryota	O	actinin binding	rga1	GO:0000003,GO:0000131,GO:0000278,GO:0000281,GO:0000746,GO:0000747,GO:0000755,GO:0000910,GO:0000917,GO:0003006,GO:0003674,GO:0003824,GO:0005096,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005886,GO:0005933,GO:0005934,GO:0005935,GO:0005937,GO:0006109,GO:0006508,GO:0006807,GO:0006950,GO:0006952,GO:0006996,GO:0007010,GO:0007049,GO:0007275,GO:0008047,GO:0008150,GO:0008152,GO:0008233,GO:0008285,GO:0008360,GO:0009266,GO:0009272,GO:0009409,GO:0009628,GO:0009653,GO:0009791,GO:0009888,GO:0009889,GO:0009908,GO:0009966,GO:0009968,GO:0009987,GO:0010087,GO:0010088,GO:0010154,GO:0010556,GO:0010646,GO:0010648,GO:0010675,GO:0010962,GO:0010981,GO:0016020,GO:0016043,GO:0016787,GO:0019222,GO:0019538,GO:0019904,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022622,GO:0023051,GO:0023057,GO:0030016,GO:0030017,GO:0030029,GO:0030036,GO:0030234,GO:0030427,GO:0030695,GO:0031323,GO:0031326,GO:0031430,GO:0031672,GO:0032182,GO:0032501,GO:0032502,GO:0032505,GO:0032506,GO:0032881,GO:0032885,GO:0032950,GO:0032951,GO:0032952,GO:0032953,GO:0032995,GO:0035023,GO:0035024,GO:0035670,GO:0040008,GO:0042127,GO:0042546,GO:0042995,GO:0043085,GO:0043087,GO:0043130,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043255,GO:0043292,GO:0043332,GO:0043547,GO:0044085,GO:0044087,GO:0044093,GO:0044238,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044463,GO:0044464,GO:0044703,GO:0044764,GO:0045926,GO:0046578,GO:0046580,GO:0046620,GO:0046621,GO:0048316,GO:0048317,GO:0048364,GO:0048367,GO:0048437,GO:0048438,GO:0048440,GO:0048444,GO:0048445,GO:0048467,GO:0048481,GO:0048482,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048608,GO:0048638,GO:0048640,GO:0048731,GO:0048827,GO:0048831,GO:0048856,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051056,GO:0051058,GO:0051093,GO:0051094,GO:0051128,GO:0051179,GO:0051239,GO:0051240,GO:0051241,GO:0051286,GO:0051301,GO:0051336,GO:0051345,GO:0051641,GO:0051666,GO:0051704,GO:0055120,GO:0060237,GO:0060255,GO:0060589,GO:0061458,GO:0061640,GO:0065007,GO:0065008,GO:0065009,GO:0071554,GO:0071704,GO:0071840,GO:0071852,GO:0071944,GO:0080090,GO:0090036,GO:0090038,GO:0090334,GO:0090529,GO:0090567,GO:0090696,GO:0090697,GO:0090698,GO:0098772,GO:0099080,GO:0099081,GO:0099402,GO:0099512,GO:0120025,GO:0120038,GO:0140096,GO:1900055,GO:1900057,GO:1901564,GO:1902410,GO:1902531,GO:1902532,GO:1903047,GO:1903338,GO:1905392,GO:1905623,GO:2000024,GO:2000026,GO:2000112	-	ko:K17964	-	-	-	-	ko00000,ko03029	-	-	-	DA1-like,LIM,RhoGAP,UIM
WLSH3_k127_6572978_1	1379698.RBG1_1C00001G0112	3.709e-54	197.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6572978_0	1379698.RBG1_1C00001G0113	7.483e-75	260.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6572978_2	459349.CLOAM0025	3.238e-29	120.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6636851_4	1274374.CBLK010000072_gene1002	8.292e-05	55.0	COG0760@1|root,COG0760@2|Bacteria,1UZZM@1239|Firmicutes,4HE14@91061|Bacilli,26RHI@186822|Paenibacillaceae	91061|Bacilli	O	peptidyl-prolyl isomerase	yacD	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
WLSH3_k127_6636851_3	1094558.ME5_00870	1.546e-05	57.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,48T75@772|Bartonellaceae	28211|Alphaproteobacteria	M	PPIC-type PPIASE domain	ppiC	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
WLSH3_k127_6636851_1	1499967.BAYZ01000014_gene6354	7.937e-132	430.0	COG1085@1|root,COG1085@2|Bacteria,2NQQM@2323|unclassified Bacteria	2|Bacteria	C	Domain of unknown function (DUF4921)	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0896	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
WLSH3_k127_6636851_0	316067.Geob_1010	1.407e-139	459.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA-2	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Alpha-amylase,Glyco_transf_5,Glycos_transf_1
WLSH3_k127_6636851_2	204669.Acid345_0708	1.836e-37	141.0	COG1100@1|root,COG1100@2|Bacteria,3Y7CQ@57723|Acidobacteria	57723|Acidobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
WLSH3_k127_6640400_6	1121346.KB899818_gene2590	1.937e-12	69.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
WLSH3_k127_6640400_0	861299.J421_3743	6.544e-149	487.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH3_k127_6640400_7	338963.Pcar_0504	4.971e-06	55.0	2BP69@1|root,32HXD@2|Bacteria,1Q1KM@1224|Proteobacteria,437BM@68525|delta/epsilon subdivisions,2X2GS@28221|Deltaproteobacteria,43VCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_6640400_8	1499967.BAYZ01000065_gene6112	2.211e-05	54.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WLSH3_k127_6640400_2	1121324.CLIT_10c01790	5.326e-55	201.0	COG2041@1|root,COG2041@2|Bacteria,1UZMG@1239|Firmicutes,25DEZ@186801|Clostridia	186801|Clostridia	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
WLSH3_k127_6640400_3	1278073.MYSTI_02245	8.971e-38	147.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WLSH3_k127_6640400_9	1304284.L21TH_1836	0.0002798	45.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,36DG2@31979|Clostridiaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH3_k127_6640400_4	1278073.MYSTI_03459	7.53e-33	141.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2YVFR@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WLSH3_k127_6640400_5	335543.Sfum_3650	5.508e-19	89.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MQME@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
WLSH3_k127_6640400_1	1047013.AQSP01000142_gene195	4.581e-136	442.0	COG0787@1|root,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WLSH3_k127_6668000_2	338966.Ppro_2787	2.131e-08	60.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria,43T2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
WLSH3_k127_6668000_0	1123376.AUIU01000014_gene591	1.015e-112	380.0	COG1009@1|root,COG1009@2|Bacteria,3J0AN@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-quinone oxidoreductase	-	-	1.6.5.3	ko:K00341,ko:K12139	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
WLSH3_k127_6668000_1	573063.Metin_0552	5.472e-09	61.0	COG0680@1|root,arCOG04429@2157|Archaea	2157|Archaea	C	PFAM peptidase M52 hydrogen uptake protein	hycI	GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WLSH3_k127_6689245_0	335543.Sfum_1003	1.451e-197	630.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2WJJV@28221|Deltaproteobacteria,2MRHA@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WLSH3_k127_6731488_1	1379698.RBG1_1C00001G0260	2.94e-69	243.0	COG0706@1|root,COG0706@2|Bacteria,2NP6C@2323|unclassified Bacteria	2|Bacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WLSH3_k127_6731488_2	1121430.JMLG01000002_gene1319	1.908e-33	142.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,260UK@186807|Peptococcaceae	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
WLSH3_k127_6731488_0	545694.TREPR_0393	3.64e-99	328.0	COG0281@1|root,COG0281@2|Bacteria,2J5DN@203691|Spirochaetes	203691|Spirochaetes	C	Malic enzyme, NAD binding domain	mdh	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
WLSH3_k127_6734820_1	443143.GM18_0868	4.003e-104	345.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
WLSH3_k127_6734820_0	1157490.EL26_05420	1.531e-128	416.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,277VR@186823|Alicyclobacillaceae	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WLSH3_k127_6817153_1	649747.HMPREF0083_00359	1.814e-38	149.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,4HDIE@91061|Bacilli,26VH3@186822|Paenibacillaceae	91061|Bacilli	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH3_k127_6817153_3	68170.KL590503_gene325	1.792e-07	63.0	COG1240@1|root,COG1240@2|Bacteria,2I2N9@201174|Actinobacteria,4EDRJ@85010|Pseudonocardiales	201174|Actinobacteria	H	von Willebrand factor type A domain	chlI	-	6.6.1.1	ko:K03404,ko:K13580	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	VWA_2
WLSH3_k127_6817153_0	2325.TKV_c05160	8.962e-98	331.0	COG1239@1|root,COG1239@2|Bacteria,1UHYK@1239|Firmicutes,24BJ0@186801|Clostridia,42ESQ@68295|Thermoanaerobacterales	186801|Clostridia	H	Magnesium chelatase, subunit ChlI	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
WLSH3_k127_6817153_2	1094980.Mpsy_0037	3.521e-31	124.0	arCOG05108@1|root,arCOG05108@2157|Archaea,2Y05F@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Stress responsive alpha-beta barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
WLSH3_k127_6820038_0	671143.DAMO_1073	1.826e-317	983.0	COG0542@1|root,COG0542@2|Bacteria,2NNNE@2323|unclassified Bacteria	2|Bacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03694,ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WLSH3_k127_6820038_3	522306.CAP2UW1_1822	4.046e-05	47.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
WLSH3_k127_6820038_1	909663.KI867150_gene485	5.243e-40	150.0	COG1148@1|root,COG1148@2|Bacteria,1N26U@1224|Proteobacteria,43EWE@68525|delta/epsilon subdivisions,2X2B6@28221|Deltaproteobacteria,2MRJK@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH3_k127_6836711_1	289376.THEYE_A0592	2.938e-128	422.0	COG1030@1|root,COG1030@2|Bacteria,3J0WF@40117|Nitrospirae	40117|Nitrospirae	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
WLSH3_k127_6836711_0	945713.IALB_2166	1.06e-134	432.0	COG2820@1|root,COG2820@2|Bacteria	2|Bacteria	F	uridine phosphorylase activity	amn	-	2.4.2.3,3.2.2.4	ko:K00757,ko:K01241	ko00230,ko00240,ko00983,ko01100,map00230,map00240,map00983,map01100	-	R00182,R01876,R02484,R08229	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WLSH3_k127_6836711_2	1379698.RBG1_1C00001G1648	2.91e-75	260.0	COG1043@1|root,COG1043@2|Bacteria,2NP5V@2323|unclassified Bacteria	2|Bacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
WLSH3_k127_6864214_0	1379698.RBG1_1C00001G1511	3.886e-96	319.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_6864214_1	1379698.RBG1_1C00001G1510	6.298e-83	291.0	COG0312@1|root,COG0312@2|Bacteria,2NP7I@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldE2	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_6869559_0	1379698.RBG1_1C00001G0304	2.403e-17	82.0	COG0413@1|root,COG0413@2|Bacteria,2NP1G@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
WLSH3_k127_6884889_0	118173.KB235914_gene4218	1.845e-72	259.0	COG0457@1|root,COG0457@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
WLSH3_k127_6884889_1	997352.HMPREF9419_1245	3.93e-10	72.0	COG1555@1|root,COG1555@2|Bacteria,4NE88@976|Bacteroidetes,2FP15@200643|Bacteroidia	976|Bacteroidetes	L	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
WLSH3_k127_6893311_0	868131.MSWAN_0749	1.364e-167	547.0	COG0370@1|root,arCOG00359@2157|Archaea,2XU46@28890|Euryarchaeota,23PFY@183925|Methanobacteria	183925|Methanobacteria	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WLSH3_k127_6906868_1	338966.Ppro_0727	5.909e-23	100.0	COG0655@1|root,COG0655@2|Bacteria,1N3NQ@1224|Proteobacteria,42TRR@68525|delta/epsilon subdivisions,2WQ13@28221|Deltaproteobacteria,43VWV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WLSH3_k127_6906868_2	1121904.ARBP01000012_gene1352	1.249e-20	100.0	COG1462@1|root,COG1462@2|Bacteria,4NZTS@976|Bacteroidetes	976|Bacteroidetes	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
WLSH3_k127_6906868_0	909663.KI867150_gene485	1.646e-39	149.0	COG1148@1|root,COG1148@2|Bacteria,1N26U@1224|Proteobacteria,43EWE@68525|delta/epsilon subdivisions,2X2B6@28221|Deltaproteobacteria,2MRJK@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH3_k127_6920793_3	985665.HPL003_13490	1.294e-12	74.0	COG1813@1|root,COG1813@2|Bacteria,1VEVE@1239|Firmicutes,4ITB7@91061|Bacilli,26XW0@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix domain	yonR	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WLSH3_k127_6920793_4	1236689.MMALV_10810	1.466e-10	67.0	arCOG03272@1|root,arCOG03272@2157|Archaea,2Y1VM@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	2.7.7.6	ko:K00960	-	-	-	-	ko00000,ko01000	-	-	-	-
WLSH3_k127_6920793_0	1380387.JADM01000001_gene486	3.747e-249	775.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,1RNE7@1236|Gammaproteobacteria,1XI34@135619|Oceanospirillales	135619|Oceanospirillales	P	Catalase	-	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
WLSH3_k127_6920793_2	1173027.Mic7113_3239	9.171e-35	149.0	COG0457@1|root,COG3903@1|root,COG4995@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H84Z@1150|Oscillatoriales	1117|Cyanobacteria	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
WLSH3_k127_6920793_1	1502770.JQMG01000001_gene1308	1.827e-45	183.0	COG0834@1|root,COG2199@1|root,COG0834@2|Bacteria,COG3706@2|Bacteria,1QUXS@1224|Proteobacteria,2VSNE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE3,PAS_3,PAS_4
WLSH3_k127_6930994_0	44251.PDUR_24900	1.944e-120	401.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli,26T5K@186822|Paenibacillaceae	91061|Bacilli	GM	ABC transporter	rgpD	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
WLSH3_k127_6930994_1	1499967.BAYZ01000049_gene2758	2.5e-107	354.0	COG1682@1|root,COG1682@2|Bacteria,2NQ2H@2323|unclassified Bacteria	2|Bacteria	U	ABC-2 type transporter	rfbA5	-	-	ko:K09690,ko:K09692	ko02010,map02010	M00250,M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103,3.A.1.104	-	-	ABC2_membrane
WLSH3_k127_6986211_1	871963.Desdi_2186	2.587e-46	171.0	COG1666@1|root,COG1666@2|Bacteria,1V3UR@1239|Firmicutes,24HUX@186801|Clostridia,261V6@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
WLSH3_k127_6986211_2	1379698.RBG1_1C00001G0867	2.615e-12	77.0	COG2834@1|root,COG2834@2|Bacteria,2NQ6V@2323|unclassified Bacteria	2|Bacteria	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
WLSH3_k127_6986211_0	1191523.MROS_1729	6.735e-67	234.0	COG1674@1|root,COG1674@2|Bacteria	2|Bacteria	D	ftsk spoiiie	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH3_k127_7002176_1	748449.Halha_2223	2.85e-71	251.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,3WAEW@53433|Halanaerobiales	186801|Clostridia	S	BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WLSH3_k127_7002176_0	697281.Mahau_1643	1.371e-96	334.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,42FR9@68295|Thermoanaerobacterales	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
WLSH3_k127_7002176_2	1120746.CCNL01000004_gene101	4.398e-46	168.0	COG1691@1|root,COG1691@2|Bacteria,2NPQT@2323|unclassified Bacteria	2|Bacteria	S	AIR carboxylase	larB	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
WLSH3_k127_7025278_8	593750.Metfor_1602	1.513e-09	59.0	COG1373@1|root,arCOG03167@2157|Archaea,2Y2NX@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WLSH3_k127_7025278_5	1313304.CALK_1777	5.15e-24	102.0	COG0051@1|root,COG0051@2|Bacteria	2|Bacteria	J	cytoplasmic translation	rpsJ	GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
WLSH3_k127_7025278_1	428125.CLOLEP_01036	2.71e-63	223.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WHH0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
WLSH3_k127_7025278_2	1123009.AUID01000026_gene192	2.256e-47	177.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,268PJ@186813|unclassified Clostridiales	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
WLSH3_k127_7025278_6	330214.NIDE1313	7.676e-23	104.0	COG0089@1|root,COG0089@2|Bacteria,3J0TP@40117|Nitrospirae	40117|Nitrospirae	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
WLSH3_k127_7025278_0	945713.IALB_0915	2.974e-115	376.0	COG0090@1|root,COG0090@2|Bacteria	2|Bacteria	J	rRNA binding	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WLSH3_k127_7025278_4	1168289.AJKI01000011_gene469	8.36e-36	139.0	COG0185@1|root,COG0185@2|Bacteria,4NQ8T@976|Bacteroidetes,2FT46@200643|Bacteroidia,3XK8Z@558415|Marinilabiliaceae	976|Bacteroidetes	J	Ribosomal protein S19	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
WLSH3_k127_7025278_7	1122211.JMLW01000001_gene2110	1.263e-21	98.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1XK4T@135619|Oceanospirillales	135619|Oceanospirillales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
WLSH3_k127_7025278_3	880073.Calab_2132	6.457e-45	166.0	COG0092@1|root,COG0092@2|Bacteria,2NP6J@2323|unclassified Bacteria	2|Bacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WLSH3_k127_7038925_8	1173029.JH980292_gene3026	0.0005401	43.0	COG0579@1|root,COG0579@2|Bacteria,1G0XV@1117|Cyanobacteria,1HA8I@1150|Oscillatoriales	1117|Cyanobacteria	C	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
WLSH3_k127_7038925_5	671143.DAMO_0351	1.553e-49	184.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7038925_2	237368.SCABRO_03013	1.159e-62	225.0	28MYQ@1|root,2ZB5K@2|Bacteria,2IZUC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7038925_4	247490.KSU1_B0649	1.171e-49	184.0	29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7038925_0	1379698.RBG1_1C00001G0119	1.221e-97	332.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7038925_7	671143.DAMO_0351	5.147e-47	177.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7038925_3	247490.KSU1_B0648	5.047e-58	212.0	28MYQ@1|root,2ZB5K@2|Bacteria,2IZUC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7038925_6	247490.KSU1_B0649	5.803e-49	181.0	29ZH8@1|root,30MGZ@2|Bacteria,2J0G3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7038925_1	671143.DAMO_0348	5.023e-81	275.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7043914_4	1237149.C900_03663	2.732e-08	60.0	2CIAQ@1|root,2ZXJG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7043914_0	44251.PDUR_17875	3.604e-68	235.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,4IPP0@91061|Bacilli,2716A@186822|Paenibacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WLSH3_k127_7043914_2	889378.Spiaf_0474	6.713e-14	79.0	28QN8@1|root,2ZD3W@2|Bacteria,2JBCA@203691|Spirochaetes	203691|Spirochaetes	S	DOMON domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7043914_5	109760.SPPG_00747T0	2.219e-05	50.0	COG0695@1|root,KOG1752@2759|Eukaryota,3A8AE@33154|Opisthokonta,3P6QI@4751|Fungi	4751|Fungi	O	Glutaredoxin	TTR1	GO:0003674,GO:0003824,GO:0004364,GO:0004601,GO:0004602,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006464,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010731,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016684,GO:0016740,GO:0016765,GO:0019538,GO:0033554,GO:0034599,GO:0034641,GO:0036211,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:0098869,GO:1901564,GO:1990748	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	iMM904.YDR513W	Glutaredoxin
WLSH3_k127_7043914_1	192952.MM_3270	1.049e-46	175.0	COG4802@1|root,arCOG01100@2157|Archaea,2XXWK@28890|Euryarchaeota,2NAWN@224756|Methanomicrobia	224756|Methanomicrobia	C	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
WLSH3_k127_7043914_6	517418.Ctha_2372	0.0001598	51.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,DUF4625,NPCBM_assoc,PEGA
WLSH3_k127_7046285_3	272123.Anacy_1669	1.893e-42	158.0	2DNS7@1|root,32YWC@2|Bacteria,1G8QD@1117|Cyanobacteria,1HP4W@1161|Nostocales	1117|Cyanobacteria	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WLSH3_k127_7046285_2	1128421.JAGA01000004_gene2533	3.301e-50	190.0	COG1597@1|root,COG1597@2|Bacteria,2NQYH@2323|unclassified Bacteria	2|Bacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat,DUF389
WLSH3_k127_7046285_0	523845.AQXV01000051_gene1260	9.624e-202	644.0	COG1509@1|root,arCOG03246@2157|Archaea,2XW0K@28890|Euryarchaeota,23QRT@183939|Methanococci	183939|Methanococci	E	TIGRFAM lysine 2,3-aminomutase YodO family protein	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
WLSH3_k127_7046285_1	515635.Dtur_1496	1.065e-90	310.0	COG0301@1|root,COG1293@1|root,COG0301@2|Bacteria,COG1293@2|Bacteria	2|Bacteria	K	actin binding	FbpA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	DUF814,FbpA,ThiI
WLSH3_k127_7046285_4	1191523.MROS_2507	6.13e-10	66.0	28PR3@1|root,2ZCD0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7046285_5	1047013.AQSP01000140_gene2512	8.581e-06	51.0	COG1226@1|root,COG1226@2|Bacteria,2NP71@2323|unclassified Bacteria	2|Bacteria	U	Ion channel	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
WLSH3_k127_7068760_0	468059.AUHA01000002_gene214	1.849e-71	244.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1IP7S@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_7068760_1	1173026.Glo7428_2825	1.245e-39	151.0	COG0614@1|root,COG0614@2|Bacteria,1G73G@1117|Cyanobacteria	1117|Cyanobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH3_k127_7068760_2	1121405.dsmv_1037	5.77e-39	159.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2MHP7@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WLSH3_k127_7068760_3	926554.KI912636_gene3052	3.215e-15	87.0	COG3121@1|root,COG3121@2|Bacteria,1WITE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7072721_0	323259.Mhun_0382	2.822e-120	395.0	COG0381@1|root,arCOG01392@2157|Archaea,2XU0B@28890|Euryarchaeota	28890|Euryarchaeota	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
WLSH3_k127_7072721_1	1519464.HY22_06365	8.346e-57	207.0	COG0438@1|root,COG0438@2|Bacteria,1FE81@1090|Chlorobi	1090|Chlorobi	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
WLSH3_k127_7086426_1	1499967.BAYZ01000019_gene6320	4.522e-22	106.0	COG0009@1|root,COG0009@2|Bacteria,2NPMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the SUA5 family	prmC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WLSH3_k127_7086426_2	429009.Adeg_0069	3.234e-20	100.0	COG0394@1|root,COG0394@2|Bacteria,1VA05@1239|Firmicutes,25CRM@186801|Clostridia,42GVA@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ywlE	-	3.1.3.48,3.9.1.2	ko:K01104,ko:K20201	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WLSH3_k127_7086426_0	880073.Calab_3769	4.53e-88	301.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WLSH3_k127_7147579_4	1123060.JONP01000009_gene2108	2.762e-10	61.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2JRWE@204441|Rhodospirillales	28211|Alphaproteobacteria	H	Pyridoxal phosphate biosynthetic protein PdxA	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
WLSH3_k127_7147579_0	765420.OSCT_2337	1.254e-34	135.0	COG2331@1|root,COG2331@2|Bacteria,2G795@200795|Chloroflexi,375UE@32061|Chloroflexia	32061|Chloroflexia	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH3_k127_7147579_3	755178.Cyan10605_3080	3.23e-17	95.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria	1117|Cyanobacteria	F	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
WLSH3_k127_7147579_2	45351.EDO28725	2.886e-28	132.0	COG0457@1|root,KOG0548@2759|Eukaryota,38GAN@33154|Opisthokonta,3BEXQ@33208|Metazoa	33208|Metazoa	O	regulation of mitotic cell cycle	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,DED,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
WLSH3_k127_7147579_1	671143.DAMO_3128	2.823e-32	129.0	COG0730@1|root,COG0730@2|Bacteria,2NRPD@2323|unclassified Bacteria	2|Bacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WLSH3_k127_715207_1	476272.RUMHYD_01829	5.777e-70	244.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3XYI9@572511|Blautia	186801|Clostridia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH3_k127_715207_2	671143.DAMO_3001	2.117e-65	233.0	COG1989@1|root,COG1989@2|Bacteria,2NPDS@2323|unclassified Bacteria	2|Bacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02236,ko:K02278,ko:K02506,ko:K02654,ko:K10966	-	M00331,M00429	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WLSH3_k127_715207_0	1379698.RBG1_1C00001G1789	9.431e-136	477.0	COG1572@1|root,COG1572@2|Bacteria,2NP03@2323|unclassified Bacteria	2|Bacteria	S	Propeptide_C25	porU	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
WLSH3_k127_715207_3	880073.Calab_1394	7.229e-05	55.0	COG2067@1|root,COG2067@2|Bacteria,2NPQZ@2323|unclassified Bacteria	2|Bacteria	I	Two component regulator propeller	porV	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7157433_2	452471.Aasi_0966	6.344e-16	90.0	COG0457@1|root,COG2842@1|root,COG0457@2|Bacteria,COG2842@2|Bacteria,4NMWW@976|Bacteroidetes,47SGQ@768503|Cytophagia	976|Bacteroidetes	L	SUPERFAMILY SSF53098, Polynucleotidyl transferase, Ribonuclease H fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974,NB-ARC,Sel1,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8
WLSH3_k127_7157433_0	330214.NIDE3065	4.617e-48	187.0	COG4942@1|root,COG4942@2|Bacteria,3J0SP@40117|Nitrospirae	40117|Nitrospirae	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
WLSH3_k127_7157433_1	330214.NIDE1417	1.246e-17	89.0	COG1354@1|root,COG1354@2|Bacteria,3J13J@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WLSH3_k127_7170182_3	404380.Gbem_3970	6.649e-74	268.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,43UK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WLSH3_k127_7170182_5	1379698.RBG1_1C00001G0649	1.8e-52	199.0	COG2045@1|root,COG2045@2|Bacteria,2NPF1@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ComB family	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
WLSH3_k127_7170182_0	1379698.RBG1_1C00001G1502	3.991e-133	434.0	COG2805@1|root,COG2805@2|Bacteria,2NP0T@2323|unclassified Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH3_k127_7170182_4	635013.TherJR_1731	6.109e-67	233.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,261EB@186807|Peptococcaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WLSH3_k127_7170182_2	871968.DESME_10505	3.434e-95	323.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,260BG@186807|Peptococcaceae	186801|Clostridia	E	PFAM peptidase M24	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
WLSH3_k127_7170182_6	443143.GM18_1392	7.596e-23	113.0	COG0457@1|root,COG0457@2|Bacteria,1NEMW@1224|Proteobacteria,42WBX@68525|delta/epsilon subdivisions,2WRAD@28221|Deltaproteobacteria,43VAR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_8
WLSH3_k127_7170182_1	1304874.JAFY01000007_gene2463	8.788e-106	356.0	COG0182@1|root,COG0182@2|Bacteria,3TA3K@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
WLSH3_k127_7170182_7	555079.Toce_0738	1.958e-22	98.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,42GIM@68295|Thermoanaerobacterales	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WLSH3_k127_7181443_1	880073.Calab_3019	2.533e-53	199.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
WLSH3_k127_7181443_0	335543.Sfum_3516	7.717e-139	447.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2MQTV@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
WLSH3_k127_7209338_3	759914.BP951000_1919	0.0001924	46.0	COG1825@1|root,COG1825@2|Bacteria,2J75H@203691|Spirochaetes	203691|Spirochaetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WLSH3_k127_7209338_0	1123508.JH636445_gene6803	3.296e-42	162.0	COG0193@1|root,COG0193@2|Bacteria,2IZXT@203682|Planctomycetes	203682|Planctomycetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WLSH3_k127_7209338_2	272562.CA_C3724	9.274e-20	96.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,36JK5@31979|Clostridiaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WLSH3_k127_7209338_1	945713.IALB_0594	1.745e-35	139.0	COG0629@1|root,COG0629@2|Bacteria	2|Bacteria	L	single-stranded DNA binding	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH3_k127_7209338_4	1160707.AJIK01000021_gene1829	0.0002535	46.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,26EYY@186818|Planococcaceae	91061|Bacilli	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WLSH3_k127_7218266_0	635013.TherJR_1798	8.26e-164	542.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25ZXM@186807|Peptococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WLSH3_k127_7218266_5	1121448.DGI_0529	2.464e-57	210.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria,2MF83@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
WLSH3_k127_7218266_9	290512.Paes_1799	7.821e-05	51.0	29GCI@1|root,303AD@2|Bacteria,1FE3Q@1090|Chlorobi	1090|Chlorobi	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
WLSH3_k127_7218266_2	574087.Acear_2052	2.362e-96	331.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WA7H@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WLSH3_k127_7218266_7	1121472.AQWN01000002_gene2206	3.196e-27	118.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,26220@186807|Peptococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
WLSH3_k127_7218266_8	909663.KI867151_gene3034	3.945e-25	115.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,2MQKS@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WLSH3_k127_7218266_6	485916.Dtox_3739	2.556e-42	160.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WLSH3_k127_7218266_1	1379698.RBG1_1C00001G1545	1.704e-163	529.0	COG0745@1|root,COG0745@2|Bacteria,2NNXK@2323|unclassified Bacteria	2|Bacteria	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
WLSH3_k127_7218266_3	1379698.RBG1_1C00001G1544	6.265e-95	325.0	COG4191@1|root,COG4191@2|Bacteria,2NPC5@2323|unclassified Bacteria	2|Bacteria	T	Integral membrane sensor signal transduction histidine kinase	vicK	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K07709,ko:K13924	ko02020,ko02030,map02020,map02030	M00499,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
WLSH3_k127_7218266_4	357808.RoseRS_1949	1.467e-73	284.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
WLSH3_k127_7287792_0	1089548.KI783301_gene1572	2.428e-96	329.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4HBYZ@91061|Bacilli,3WFEC@539002|Bacillales incertae sedis	91061|Bacilli	J	Uncharacterized protein family UPF0004	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH3_k127_7287792_1	938289.CAJN020000002_gene643	6.674e-62	221.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,267K9@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WLSH3_k127_72926_2	517418.Ctha_2329	6.245e-14	77.0	COG0810@1|root,COG0810@2|Bacteria,1FE18@1090|Chlorobi	1090|Chlorobi	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WLSH3_k127_72926_0	401526.TcarDRAFT_0365	1.515e-93	315.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,4H2DY@909932|Negativicutes	909932|Negativicutes	C	Phosphate acetyl/butaryl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PTA_PTB
WLSH3_k127_72926_1	398767.Glov_2700	8.521e-63	227.0	COG2199@1|root,COG3706@2|Bacteria,1RAKG@1224|Proteobacteria,42QYD@68525|delta/epsilon subdivisions,2WN6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
WLSH3_k127_7318686_0	243231.GSU2066	0.0	1059.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,43T8I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
WLSH3_k127_7320113_1	1550091.JROE01000002_gene514	1.741e-65	233.0	COG4552@1|root,COG4552@2|Bacteria,4NQGR@976|Bacteroidetes	976|Bacteroidetes	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH3_k127_7320113_0	1379698.RBG1_1C00001G0723	1.849e-69	250.0	COG0860@1|root,COG0860@2|Bacteria,2NPCZ@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
WLSH3_k127_7320113_4	1548151.LS70_10310	1.106e-06	60.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	Glyco_trans_1_2,Glycos_transf_1,Glycos_transf_2
WLSH3_k127_7320113_3	880073.Calab_3006	1.464e-19	89.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WLSH3_k127_7320113_2	880073.Calab_3006	7.137e-61	219.0	COG3146@1|root,COG3146@2|Bacteria	2|Bacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WLSH3_k127_7361199_3	1379698.RBG1_1C00001G1038	9.448e-76	269.0	COG0859@1|root,COG0859@2|Bacteria,2NPXQ@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WLSH3_k127_7361199_4	1379698.RBG1_1C00001G1249	2.13e-55	203.0	COG3170@1|root,COG3170@2|Bacteria,2NPQF@2323|unclassified Bacteria	2|Bacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
WLSH3_k127_7361199_1	352165.HMPREF7215_0319	4.684e-102	349.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7361199_2	1242864.D187_001368	1.041e-88	304.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2YUTZ@29|Myxococcales	28221|Deltaproteobacteria	M	Mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
WLSH3_k127_7361199_0	767817.Desgi_2133	1.207e-111	385.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,26105@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM Na Pi-cotransporter II-related protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
WLSH3_k127_7361199_7	1449126.JQKL01000065_gene2146	9.898e-17	83.0	2DNY2@1|root,32ZR4@2|Bacteria,1VEGZ@1239|Firmicutes,24RGC@186801|Clostridia,26C4V@186813|unclassified Clostridiales	186801|Clostridia	S	Late competence development protein ComFB	comFB	-	-	ko:K02241	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComFB
WLSH3_k127_7361199_6	880073.Calab_2067	6.828e-17	93.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7361199_5	868131.MSWAN_1275	1.164e-42	168.0	COG0438@1|root,arCOG01411@2157|Archaea,2XW22@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH3_k127_7366236_0	768704.Desmer_4433	2.698e-30	139.0	COG2247@1|root,COG2333@1|root,COG2247@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,LTD,Lactamase_B
WLSH3_k127_7366236_1	880073.Calab_2081	1.801e-15	91.0	COG3291@1|root,COG5276@1|root,COG3291@2|Bacteria,COG5276@2|Bacteria,2NQ2P@2323|unclassified Bacteria	2|Bacteria	P	LVIVD repeat	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	LVIVD
WLSH3_k127_7366581_2	509191.AEDB02000094_gene4176	7.871e-05	53.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,2484V@186801|Clostridia,3WGHV@541000|Ruminococcaceae	186801|Clostridia	E	YoaP-like	yoaP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
WLSH3_k127_7366581_0	269797.Mbar_A2597	7.69e-35	150.0	COG0457@1|root,arCOG06785@1|root,arCOG03047@2157|Archaea,arCOG06785@2157|Archaea,2Y7RD@28890|Euryarchaeota	28890|Euryarchaeota	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_12,TPR_7
WLSH3_k127_7366581_1	1033734.CAET01000077_gene2848	3.534e-15	80.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HIQ3@91061|Bacilli,1ZCW1@1386|Bacillus	91061|Bacilli	CO	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c	resA	GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WLSH3_k127_7424114_3	1379281.AVAG01000052_gene913	2.746e-07	53.0	COG2258@1|root,COG2258@2|Bacteria,1RIAF@1224|Proteobacteria,42RG1@68525|delta/epsilon subdivisions,2WNX7@28221|Deltaproteobacteria,2MGGA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
WLSH3_k127_7424114_2	1189620.AJXL01000210_gene105	3.485e-37	144.0	COG2852@1|root,COG2852@2|Bacteria,4NVZP@976|Bacteroidetes,1I5RJ@117743|Flavobacteriia,2P0DG@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
WLSH3_k127_7424114_1	1166948.JPZL01000001_gene2181	1.66e-49	182.0	COG0315@1|root,COG1977@1|root,COG0315@2|Bacteria,COG1977@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1XJTA@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC,ThiS
WLSH3_k127_7424114_0	350688.Clos_0570	1.418e-89	304.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,36EQA@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
WLSH3_k127_7438282_0	234267.Acid_1683	8.178e-44	175.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3,AAA_5
WLSH3_k127_7458676_2	566466.NOR53_3149	7.257e-31	136.0	COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,1S9AT@1236|Gammaproteobacteria,1J9QW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
WLSH3_k127_7458676_3	1191523.MROS_0672	0.0002902	53.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	ICMT,PEMT
WLSH3_k127_7458676_1	56780.SYN_02190	3.089e-42	166.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2MQHR@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PP-loop family	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
WLSH3_k127_7458676_0	398767.Glov_0511	6.882e-49	186.0	COG1906@1|root,COG1906@2|Bacteria,1RAQQ@1224|Proteobacteria,42QZ0@68525|delta/epsilon subdivisions,2WMXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
WLSH3_k127_7465058_1	889378.Spiaf_0898	2.007e-07	55.0	COG1313@1|root,COG1313@2|Bacteria,2J68B@203691|Spirochaetes	203691|Spirochaetes	C	Radical SAM domain protein	pflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WLSH3_k127_7465058_0	1379698.RBG1_1C00001G0538	1.209e-164	537.0	COG0210@1|root,COG0210@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	pcrA	GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WLSH3_k127_7499811_0	1379698.RBG1_1C00001G0047	7.479e-99	327.0	COG3259@1|root,COG3259@2|Bacteria,2NQGS@2323|unclassified Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WLSH3_k127_7499811_1	1379698.RBG1_1C00001G0046	3.136e-15	81.0	COG0680@1|root,COG0680@2|Bacteria,2NS17@2323|unclassified Bacteria	2|Bacteria	C	Hydrogenase maturation protease	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WLSH3_k127_7499811_2	1408823.AXUS01000004_gene212	2.431e-13	74.0	28JAU@1|root,33RGI@2|Bacteria,1VSTV@1239|Firmicutes,25D98@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7524806_1	661478.OP10G_0050	2.626e-115	381.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH3_k127_7524806_0	401526.TcarDRAFT_1562	8.413e-119	389.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H2ZV@909932|Negativicutes	909932|Negativicutes	NU	twitching motility protein	yggR	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WLSH3_k127_7552602_4	312153.Pnuc_1059	3.291e-11	70.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,1JZXY@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
WLSH3_k127_7552602_3	562743.JH976438_gene2046	1.282e-20	93.0	COG1828@1|root,COG1828@2|Bacteria,1VEH1@1239|Firmicutes,4HP0E@91061|Bacilli	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
WLSH3_k127_7552602_0	1379698.RBG1_1C00001G1807	8.143e-96	320.0	COG0047@1|root,COG0047@2|Bacteria,2NP46@2323|unclassified Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WLSH3_k127_7552602_2	269799.Gmet_0018	9.566e-41	162.0	COG2206@1|root,COG3850@1|root,COG2206@2|Bacteria,COG3850@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2WP5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HD,HD_5
WLSH3_k127_7552602_1	1157490.EL26_20295	4.674e-59	209.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli,2783J@186823|Alicyclobacillaceae	91061|Bacilli	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WLSH3_k127_7594256_0	555088.DealDRAFT_3046	1.241e-140	456.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,42JHI@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WLSH3_k127_7594256_1	1304880.JAGB01000002_gene1618	1.015e-22	102.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WLSH3_k127_763253_1	28115.HR11_03120	5.071e-18	95.0	COG1538@1|root,COG1538@2|Bacteria,4NF4V@976|Bacteroidetes,2FM0S@200643|Bacteroidia,22WY2@171551|Porphyromonadaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WLSH3_k127_763253_0	439235.Dalk_2025	2.358e-73	250.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MIZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	ybhF-C	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
WLSH3_k127_7669768_2	1121957.ATVL01000007_gene2353	1.713e-27	132.0	COG2374@1|root,COG3291@1|root,COG4733@1|root,COG2374@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NHB6@976|Bacteroidetes	976|Bacteroidetes	G	Cellulose binding domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CBM_3
WLSH3_k127_7669768_1	1121285.AUFK01000019_gene92	2.846e-41	177.0	COG1345@1|root,COG3209@1|root,COG1345@2|Bacteria,COG3209@2|Bacteria,4NHMH@976|Bacteroidetes,1HZTE@117743|Flavobacteriia,3ZUBT@59732|Chryseobacterium	976|Bacteroidetes	N	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494,HYR,Laminin_G_3
WLSH3_k127_7669768_3	1227739.Hsw_1561	4.489e-20	107.0	COG2353@1|root,COG2353@2|Bacteria,4PM20@976|Bacteroidetes,47X9N@768503|Cytophagia	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7669768_5	880073.Calab_0646	2.975e-05	58.0	COG1572@1|root,COG1595@1|root,COG1572@2|Bacteria,COG1595@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	CARDB,Sigma70_r4_2
WLSH3_k127_7669768_0	28229.ND2E_1921	2.729e-46	184.0	2C2F5@1|root,30VYX@2|Bacteria,1MZFF@1224|Proteobacteria,1SB97@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_7669768_4	317025.Tcr_0433	7.18e-13	69.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,461YN@72273|Thiotrichales	72273|Thiotrichales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_7674744_1	1379698.RBG1_1C00001G1830	1.878e-23	106.0	COG1399@1|root,COG1399@2|Bacteria,2NPVD@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1399	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
WLSH3_k127_7674744_0	1121468.AUBR01000038_gene1958	6.064e-114	377.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,42F1Z@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WLSH3_k127_7674744_2	635013.TherJR_2549	6.016e-08	57.0	2DPEW@1|root,331SY@2|Bacteria,1VH50@1239|Firmicutes,24RTN@186801|Clostridia,262U9@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
WLSH3_k127_7684767_1	1121920.AUAU01000004_gene857	5.145e-150	480.0	COG1804@1|root,COG1804@2|Bacteria,3Y4ZM@57723|Acidobacteria	57723|Acidobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WLSH3_k127_7684767_0	1121920.AUAU01000004_gene856	2.293e-202	640.0	COG0065@1|root,COG0065@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	hacA	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WLSH3_k127_7688229_1	338963.Pcar_2137	5.964e-15	82.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I2@1224|Proteobacteria,42VWH@68525|delta/epsilon subdivisions,2WS2H@28221|Deltaproteobacteria,43VGF@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Fimbrial assembly protein (PilN)	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
WLSH3_k127_7688229_0	1379698.RBG1_1C00001G1258	8.94e-76	266.0	COG4972@1|root,COG4972@2|Bacteria,2NPF6@2323|unclassified Bacteria	2|Bacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
WLSH3_k127_7688229_2	402612.FP0493	5.384e-05	48.0	2DHEI@1|root,2ZZFK@2|Bacteria,4PFFR@976|Bacteroidetes,1IDB2@117743|Flavobacteriia,2NXXF@237|Flavobacterium	976|Bacteroidetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
WLSH3_k127_7816874_0	765420.OSCT_0452	1.038e-142	488.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3766E@32061|Chloroflexia	32061|Chloroflexia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
WLSH3_k127_7816874_1	518766.Rmar_2721	1.216e-98	335.0	COG2262@1|root,COG2262@2|Bacteria,4NF0P@976|Bacteroidetes,1FIUG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WLSH3_k127_7816874_2	1384049.CD29_03030	2.431e-70	254.0	COG0477@1|root,COG2814@2|Bacteria,1TS1D@1239|Firmicutes,4HCUB@91061|Bacilli,3IXH5@400634|Lysinibacillus	91061|Bacilli	EGP	Multidrug transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
WLSH3_k127_7816874_3	477974.Daud_0099	4.005e-37	149.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,261DG@186807|Peptococcaceae	186801|Clostridia	S	Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
WLSH3_k127_7835709_3	693746.OBV_36670	3.166e-09	59.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,2N6N0@216572|Oscillospiraceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
WLSH3_k127_7835709_2	404589.Anae109_3648	2.546e-24	104.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2WRJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WLSH3_k127_7835709_1	1121918.ARWE01000001_gene2103	9.286e-36	140.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WLSH3_k127_7835709_0	909663.KI867150_gene1425	9.467e-94	311.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WLSH3_k127_7849078_0	562970.Btus_1543	1.621e-71	253.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli,2788W@186823|Alicyclobacillaceae	91061|Bacilli	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WLSH3_k127_7849078_1	1122921.KB898185_gene4013	2.261e-37	143.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,26YF0@186822|Paenibacillaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WLSH3_k127_7849078_2	111781.Lepto7376_3387	7.893e-28	116.0	COG0628@1|root,COG0628@2|Bacteria,1GCIM@1117|Cyanobacteria	1117|Cyanobacteria	S	Transmembrane protein 43	-	-	-	-	-	-	-	-	-	-	-	-	TMEM43
WLSH3_k127_786346_1	1121472.AQWN01000012_gene981	2.066e-84	288.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,260YE@186807|Peptococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WLSH3_k127_786346_0	370438.PTH_0805	2.192e-167	535.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,260QM@186807|Peptococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WLSH3_k127_786346_2	1089553.Tph_c08360	1.347e-61	216.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,42G8D@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
WLSH3_k127_786346_3	718252.FP2_25950	7.536e-15	74.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WHT9@541000|Ruminococcaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
WLSH3_k127_7875843_1	1321778.HMPREF1982_04612	7.55e-45	170.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,267YU@186813|unclassified Clostridiales	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WLSH3_k127_7875843_2	935948.KE386493_gene2416	6.451e-25	109.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,42GDP@68295|Thermoanaerobacterales	186801|Clostridia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
WLSH3_k127_7875843_0	246194.CHY_0426	1.518e-80	280.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,42EY4@68295|Thermoanaerobacterales	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
WLSH3_k127_7899974_2	1499967.BAYZ01000128_gene2582	1.147e-41	161.0	COG2414@1|root,COG2414@2|Bacteria,2NNME@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WLSH3_k127_7899974_1	771875.Ferpe_1363	2.556e-51	185.0	COG1490@1|root,COG1490@2|Bacteria,2GCYQ@200918|Thermotogae	200918|Thermotogae	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WLSH3_k127_7899974_3	1519464.HY22_02065	9.548e-07	61.0	COG0457@1|root,COG2197@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,PAS_9,Y_Y_Y
WLSH3_k127_7899974_0	265729.GS18_0205205	1.074e-96	327.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli,1ZPZV@1386|Bacillus	91061|Bacilli	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WLSH3_k127_7922699_5	7668.SPU_016624-tr	1.871e-14	77.0	COG0666@1|root,KOG4177@2759|Eukaryota,39MBZ@33154|Opisthokonta	33154|Opisthokonta	M	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
WLSH3_k127_7922699_4	5722.XP_001330759.1	1.358e-14	87.0	COG0666@1|root,KOG0504@2759|Eukaryota	2759|Eukaryota	I	protein ubiquitination	-	-	-	ko:K15502,ko:K15503	-	-	-	-	ko00000,ko01009,ko03400	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,DUF3447
WLSH3_k127_7922699_1	1047013.AQSP01000051_gene2576	4.138e-56	214.0	COG2220@1|root,COG2220@2|Bacteria,2NRBH@2323|unclassified Bacteria	2|Bacteria	S	Beta-lactamase superfamily domain	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
WLSH3_k127_7922699_2	429009.Adeg_1292	1.508e-52	199.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WLSH3_k127_7922699_0	580331.Thit_2302	3.743e-105	347.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,42FBT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WLSH3_k127_7922699_3	459349.CLOAM1790	7.624e-20	96.0	COG1572@1|root,COG1572@2|Bacteria,2NRE4@2323|unclassified Bacteria	2|Bacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cleaved_Adhesin,FlgD_ig,MAM,VCBS
WLSH3_k127_7933995_0	670487.Ocepr_1445	3.084e-193	630.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1WIRD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WLSH3_k127_7960861_1	671143.DAMO_2460	2.294e-145	475.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2NQFC@2323|unclassified Bacteria	2|Bacteria	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	mpg	-	1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8	ko:K00344,ko:K00966,ko:K01840,ko:K03431,ko:K15778,ko:K16881	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00361,M00362	R00885,R00959,R01057,R01818,R02060,R08639	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
WLSH3_k127_7960861_0	138119.DSY0219	2.144e-158	514.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
WLSH3_k127_7960861_2	1541959.KQ51_01580	9.971e-38	149.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WLSH3_k127_7960861_3	56780.SYN_00923	2.925e-20	91.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2MQRN@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WLSH3_k127_797331_0	397290.C810_00223	1.122e-164	531.0	COG1917@1|root,COG2089@1|root,COG1917@2|Bacteria,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,27K4Z@186928|unclassified Lachnospiraceae	186801|Clostridia	M	SAF	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,NeuB
WLSH3_k127_797331_2	397290.C810_00222	9.145e-15	76.0	COG1083@1|root,COG1083@2|Bacteria,1UFAT@1239|Firmicutes,24G5I@186801|Clostridia,27JP3@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
WLSH3_k127_7978402_0	1304874.JAFY01000002_gene661	2.885e-168	538.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_7978402_1	511051.CSE_00380	3.601e-64	222.0	COG4275@1|root,COG4275@2|Bacteria	2|Bacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
WLSH3_k127_7992412_1	1379698.RBG1_1C00001G0219	1.825e-24	107.0	COG0611@1|root,COG0611@2|Bacteria,2NP8J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946,ko:K07123	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2977c,iSFV_1184.SFV_0382,iYO844.BSU05900	AIRS,AIRS_C
WLSH3_k127_7992412_0	1121468.AUBR01000046_gene1917	2.39e-168	541.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42FXP@68295|Thermoanaerobacterales	186801|Clostridia	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WLSH3_k127_8011626_2	215803.DB30_6644	2.512e-29	125.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2WT4M@28221|Deltaproteobacteria,2YVRK@29|Myxococcales	28221|Deltaproteobacteria	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
WLSH3_k127_8011626_0	522772.Dacet_1395	3.657e-141	453.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2827,iAPECO1_1312.APECO1_3678,iBWG_1329.BWG_2562,iE2348C_1286.E2348C_3096,iEC042_1314.EC042_3024,iEC55989_1330.EC55989_3103,iECABU_c1320.ECABU_c31240,iECDH10B_1368.ECDH10B_2997,iECDH1ME8569_1439.ECDH1ME8569_2734,iECED1_1282.ECED1_3283,iECH74115_1262.ECH74115_4093,iECIAI1_1343.ECIAI1_2935,iECIAI39_1322.ECIAI39_3246,iECNA114_1301.ECNA114_2885,iECO103_1326.ECO103_3386,iECO111_1330.ECO111_3555,iECO26_1355.ECO26_3899,iECOK1_1307.ECOK1_3231,iECP_1309.ECP_2840,iECS88_1305.ECS88_3122,iECSE_1348.ECSE_3084,iECSF_1327.ECSF_2642,iECSP_1301.ECSP_3779,iECUMN_1333.ECUMN_3154,iECW_1372.ECW_m3069,iECs_1301.ECs3684,iEKO11_1354.EKO11_0914,iETEC_1333.ETEC_3014,iEcDH1_1363.EcDH1_0864,iEcE24377_1341.EcE24377A_3147,iEcSMS35_1347.EcSMS35_2974,iG2583_1286.G2583_3481,iJO1366.b2827,iJR904.b2827,iLF82_1304.LF82_2267,iNRG857_1313.NRG857_13965,iSSON_1240.SSON_2984,iUMN146_1321.UM146_02290,iUMNK88_1353.UMNK88_3511,iUTI89_1310.UTI89_C3229,iWFL_1372.ECW_m3069,iY75_1357.Y75_RS14705,iYL1228.KPN_03236,iZ_1308.Z4144,ic_1306.c3422	Thymidylat_synt
WLSH3_k127_8011626_1	522772.Dacet_1394	1.791e-49	183.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
WLSH3_k127_8052768_0	340099.Teth39_1035	2.13e-135	441.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,42FQT@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WLSH3_k127_8052768_1	945713.IALB_0872	4.129e-31	128.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
WLSH3_k127_8052768_2	768710.DesyoDRAFT_0825	1.471e-11	65.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,260QH@186807|Peptococcaceae	186801|Clostridia	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
WLSH3_k127_8071026_0	886379.AEWI01000046_gene3089	2.18e-169	542.0	COG1875@1|root,COG1875@2|Bacteria,4NDUI@976|Bacteroidetes,2FP3H@200643|Bacteroidia,3XJ4X@558415|Marinilabiliaceae	976|Bacteroidetes	T	PIN domain	ybeZ_1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
WLSH3_k127_8071026_1	459349.CLOAM0984	5.373e-24	108.0	COG1361@1|root,COG1361@2|Bacteria,2NS3P@2323|unclassified Bacteria	2|Bacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FlgD_ig,Peptidase_C25,Peptidase_C25_C,Propeptide_C25
WLSH3_k127_8085202_3	574087.Acear_0183	3.489e-50	182.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3WA6N@53433|Halanaerobiales	186801|Clostridia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WLSH3_k127_8085202_4	292459.STH3052	2.8e-34	132.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WLSH3_k127_8085202_5	1191523.MROS_0193	3.25e-13	70.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WLSH3_k127_8085202_2	1449126.JQKL01000050_gene2698	2.008e-50	181.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,26987@186813|unclassified Clostridiales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WLSH3_k127_8085202_1	1379698.RBG1_1C00001G1570	4.161e-54	192.0	COG0100@1|root,COG0100@2|Bacteria,2NPCN@2323|unclassified Bacteria	2|Bacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WLSH3_k127_8085202_0	264732.Moth_2432	8.992e-74	254.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,42ENH@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WLSH3_k127_8095641_0	1191523.MROS_1633	9.606e-105	367.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,CBM9_1
WLSH3_k127_8095641_3	1122947.FR7_2826	7.299e-46	177.0	COG1335@1|root,COG1335@2|Bacteria,1V7B8@1239|Firmicutes	1239|Firmicutes	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
WLSH3_k127_8095641_2	1540257.JQMW01000009_gene3867	1.117e-49	186.0	COG1708@1|root,COG1708@2|Bacteria,1UR8X@1239|Firmicutes,24W85@186801|Clostridia	186801|Clostridia	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8095641_1	1434325.AZQN01000006_gene3287	5.201e-71	245.0	2C5G3@1|root,2Z8TT@2|Bacteria,4P166@976|Bacteroidetes,47TW0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8132329_3	7668.SPU_007752-tr	4.114e-08	58.0	COG0666@1|root,KOG0504@2759|Eukaryota,38C53@33154|Opisthokonta	33154|Opisthokonta	P	phosphoric diester hydrolase activity	PHO81	GO:0001932,GO:0001933,GO:0003674,GO:0004857,GO:0004860,GO:0004861,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005794,GO:0005829,GO:0005886,GO:0006469,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0012505,GO:0016020,GO:0016538,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0030234,GO:0030291,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0042325,GO:0042326,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043549,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045936,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0098772	-	ko:K06653,ko:K15503	ko04111,map04111	-	-	-	ko00000,ko00001,ko01009,ko03400	-	-	-	Ank_2,Ank_4,GDPD,SPX
WLSH3_k127_8132329_1	309799.DICTH_0405	2.699e-114	385.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_8132329_0	309799.DICTH_0404	7.136e-186	591.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_8132329_2	1487953.JMKF01000083_gene4289	2.347e-32	138.0	COG1708@1|root,COG1708@2|Bacteria,1G4FC@1117|Cyanobacteria,1HEXH@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
WLSH3_k127_8132329_4	945713.IALB_3151	9.275e-06	52.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	ACPS,CBM9_1
WLSH3_k127_8134642_2	760192.Halhy_0695	6.603e-09	68.0	COG0457@1|root,COG1672@1|root,COG4995@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG4995@2|Bacteria,4NUFW@976|Bacteroidetes	976|Bacteroidetes	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
WLSH3_k127_8134642_0	1234364.AMSF01000095_gene2517	1.346e-29	126.0	2AQI0@1|root,31FQP@2|Bacteria,1RI31@1224|Proteobacteria,1S4IS@1236|Gammaproteobacteria,1X71C@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8134642_1	459349.CLOAM0776	2.538e-12	68.0	COG0389@1|root,COG0389@2|Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	umuC	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
WLSH3_k127_8150983_2	1232437.KL662047_gene5222	2.781e-64	227.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2MJ0P@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WLSH3_k127_8150983_3	243365.CV_4122	2.432e-50	186.0	COG0110@1|root,COG0110@2|Bacteria,1RD7F@1224|Proteobacteria,2VRQM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
WLSH3_k127_8150983_0	880072.Desac_2197	2.683e-113	379.0	COG2244@1|root,COG2244@2|Bacteria,1RC2S@1224|Proteobacteria,42QM2@68525|delta/epsilon subdivisions,2WP4N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3
WLSH3_k127_8150983_5	667014.Thein_1158	5.314e-06	57.0	COG3206@1|root,COG3206@2|Bacteria,2GI4D@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
WLSH3_k127_8150983_1	237368.SCABRO_00076	1.347e-101	348.0	COG2148@1|root,COG2148@2|Bacteria,2IX7E@203682|Planctomycetes	203682|Planctomycetes	M	involved in lipopolysaccharide	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WLSH3_k127_8150983_4	344747.PM8797T_27437	1.403e-09	64.0	COG1215@1|root,COG1215@2|Bacteria,2IXZ2@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH3_k127_8157909_0	880073.Calab_3769	1.215e-180	574.0	COG1770@1|root,COG1770@2|Bacteria,2NNMF@2323|unclassified Bacteria	2|Bacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WLSH3_k127_8157909_1	671143.DAMO_2896	2.082e-170	559.0	COG0210@1|root,COG2887@1|root,COG0210@2|Bacteria,COG2887@2|Bacteria,2NNZG@2323|unclassified Bacteria	2|Bacteria	L	UvrD/REP helicase N-terminal domain	-	-	3.6.4.12	ko:K03657,ko:K07465	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WLSH3_k127_8173035_1	1047013.AQSP01000140_gene2469	7.775e-172	545.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WLSH3_k127_8173035_0	1499967.BAYZ01000026_gene1634	7.778e-175	559.0	COG2986@1|root,COG2986@2|Bacteria,2NNRU@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WLSH3_k127_8203048_0	868595.Desca_1757	1.588e-205	651.0	COG0046@1|root,COG0046@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,260FM@186807|Peptococcaceae	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
WLSH3_k127_8207153_1	1379698.RBG1_1C00001G0549	5.384e-92	308.0	COG1137@1|root,COG1137@2|Bacteria,2NNRT@2323|unclassified Bacteria	2|Bacteria	S	lipopolysaccharide transport protein B ATP-binding component of ABC superfamily	lptB	GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K01990,ko:K06861	ko02010,map02010	M00254,M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1,3.A.1	-	-	ABC_tran,BCA_ABC_TP_C
WLSH3_k127_8207153_0	1122621.ATZA01000081_gene2814	7.158e-141	453.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,1IQ44@117747|Sphingobacteriia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
WLSH3_k127_8207153_2	706434.HMPREF9429_01014	4.145e-21	95.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4H34N@909932|Negativicutes	909932|Negativicutes	EK	Aminotransferase, class I	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
WLSH3_k127_8243079_2	1122919.KB905582_gene3720	3.471e-49	177.0	COG0388@1|root,COG0388@2|Bacteria,1U2RZ@1239|Firmicutes,4ICEP@91061|Bacilli,272G5@186822|Paenibacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
WLSH3_k127_8243079_0	1379698.RBG1_1C00001G0705	2.181e-65	239.0	COG0760@1|root,COG0760@2|Bacteria,2NPFB@2323|unclassified Bacteria	2|Bacteria	O	PPIC-type PPIASE domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N_3
WLSH3_k127_8243079_4	667014.Thein_1029	4.806e-29	126.0	COG0760@1|root,COG0760@2|Bacteria,2GHMC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
WLSH3_k127_8243079_1	1379698.RBG1_1C00001G0706	4.695e-59	226.0	COG0760@1|root,COG0760@2|Bacteria,2NR9Y@2323|unclassified Bacteria	2|Bacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3,TPR_7
WLSH3_k127_8243079_5	555779.Dthio_PD3339	1.481e-21	94.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2M8UV@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
WLSH3_k127_8243079_3	290397.Adeh_3947	7.216e-45	164.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2YZII@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
WLSH3_k127_8255694_1	335543.Sfum_3074	8.34e-34	138.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria,2MQKK@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
WLSH3_k127_8255694_0	1379698.RBG1_1C00001G0312	2.415e-197	620.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WLSH3_k127_8345629_2	401526.TcarDRAFT_1045	1.818e-35	140.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H1Y8@909932|Negativicutes	909932|Negativicutes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
WLSH3_k127_8345629_0	1379698.RBG1_1C00001G0356	8.235e-118	410.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,2NS3S@2323|unclassified Bacteria	2|Bacteria	EG	Protein of unknown function (DUF2723)	-	-	-	ko:K16928	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.33	-	-	DUF2723,QueT
WLSH3_k127_8345629_3	552811.Dehly_1408	9.05e-23	108.0	COG0375@1|root,COG0375@2|Bacteria,2G77T@200795|Chloroflexi,34DD7@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
WLSH3_k127_8345629_1	1449126.JQKL01000035_gene2154	3.299e-65	228.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,26AVX@186813|unclassified Clostridiales	186801|Clostridia	KO	Psort location Cytoplasmic, score 9.97	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
WLSH3_k127_8362794_3	243275.TDE_0162	0.000408	43.0	COG2911@1|root,COG2911@2|Bacteria,2J6UE@203691|Spirochaetes	203691|Spirochaetes	U	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	FlgD_ig
WLSH3_k127_8362794_2	671143.DAMO_2528	2.535e-45	175.0	COG2177@1|root,COG2177@2|Bacteria,2NPIM@2323|unclassified Bacteria	2|Bacteria	D	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily	ftsX	GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531	-	ko:K09811,ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
WLSH3_k127_8362794_1	1031288.AXAA01000005_gene2051	3.694e-47	174.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,36IWM@31979|Clostridiaceae	186801|Clostridia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
WLSH3_k127_8362794_0	264732.Moth_0272	2.864e-60	213.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,42G0N@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06951	-	-	-	-	ko00000	-	-	-	HD
WLSH3_k127_8363016_2	316274.Haur_4161	6.107e-06	49.0	COG2331@1|root,COG2331@2|Bacteria,2G795@200795|Chloroflexi,375UE@32061|Chloroflexia	32061|Chloroflexia	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WLSH3_k127_8363016_1	644282.Deba_2731	3.882e-65	233.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
WLSH3_k127_8363016_0	379066.GAU_2160	7.197e-72	249.0	COG2884@1|root,COG2884@2|Bacteria,1ZTHQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WLSH3_k127_8383650_0	1499967.BAYZ01000003_gene5878	1.486e-244	771.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WLSH3_k127_8399630_1	1379698.RBG1_1C00001G1127	2.101e-109	367.0	COG1570@1|root,COG1570@2|Bacteria,2NNQT@2323|unclassified Bacteria	2|Bacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6,3.4.21.102	ko:K03601,ko:K03797	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WLSH3_k127_8399630_6	411467.BACCAP_02027	1.744e-05	53.0	COG1722@1|root,COG1722@2|Bacteria,1VFJS@1239|Firmicutes,25IUP@186801|Clostridia,269QV@186813|unclassified Clostridiales	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WLSH3_k127_8399630_2	313628.LNTAR_20363	1.201e-66	243.0	COG0142@1|root,COG0142@2|Bacteria	2|Bacteria	H	isoprenoid biosynthetic process	idsA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WLSH3_k127_8399630_5	1123388.AQWU01000072_gene1349	5.02e-32	130.0	COG1963@1|root,COG1963@2|Bacteria,1WJV3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Acid phosphatase vanadium-dependent haloperoxidase related	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
WLSH3_k127_8399630_0	1121468.AUBR01000002_gene654	9.222e-219	694.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,42EPX@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
WLSH3_k127_8399630_3	1384054.N790_03915	4.287e-58	212.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1X37T@135614|Xanthomonadales	135614|Xanthomonadales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
WLSH3_k127_8399630_4	765912.Thimo_1140	3.4e-38	151.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,1WWQ1@135613|Chromatiales	135613|Chromatiales	H	Belongs to the ribF family	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WLSH3_k127_8410431_6	653733.Selin_1829	8.753e-31	126.0	COG0864@1|root,COG0864@2|Bacteria	2|Bacteria	K	response to nickel cation	nikR	GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
WLSH3_k127_8410431_4	515635.Dtur_1611	4.093e-58	206.0	COG1636@1|root,COG1636@2|Bacteria	2|Bacteria	C	queuosine biosynthetic process	queH	-	1.17.99.6,3.1.26.4	ko:K03470,ko:K09765	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03032	-	-	-	DUF208
WLSH3_k127_8410431_1	338966.Ppro_3063	7.796e-91	307.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,43SVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WLSH3_k127_8410431_2	671143.DAMO_2311	7.328e-77	263.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
WLSH3_k127_8410431_5	1294265.JCM21738_3670	9.329e-33	141.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,1ZGBC@1386|Bacillus	91061|Bacilli	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
WLSH3_k127_8410431_3	203119.Cthe_2599	1.359e-62	218.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WJ5K@541000|Ruminococcaceae	186801|Clostridia	F	Cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
WLSH3_k127_8410431_8	411489.CLOL250_02914	1.671e-06	55.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,36DG2@31979|Clostridiaceae	186801|Clostridia	NU	type II secretion system protein E	xcpR	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WLSH3_k127_8410431_0	880073.Calab_0965	3.619e-212	666.0	COG0112@1|root,COG0112@2|Bacteria,2NP28@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_3081,iIT341.HP0183	SHMT
WLSH3_k127_8435277_0	1131462.DCF50_p2397	1.404e-36	140.0	2EG8Z@1|root,32UBD@2|Bacteria,1VBQD@1239|Firmicutes,24NWB@186801|Clostridia,265M4@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8435277_1	1170562.Cal6303_2247	7.674e-15	86.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria	1117|Cyanobacteria	U	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7
WLSH3_k127_8436650_0	1379698.RBG1_1C00001G0473	3.612e-115	378.0	COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria	2|Bacteria	E	Amino acid kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452	AA_kinase
WLSH3_k127_8436650_2	1121396.KB892979_gene1696	3.809e-20	92.0	COG1146@1|root,COG1146@2|Bacteria,1NJJD@1224|Proteobacteria,42VKY@68525|delta/epsilon subdivisions,2WRXE@28221|Deltaproteobacteria,2MKYB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7
WLSH3_k127_8436650_1	338963.Pcar_1030	1.62e-91	309.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,43S62@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WLSH3_k127_8469316_1	945713.IALB_0345	6.56e-34	138.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WLSH3_k127_8469316_2	1232410.KI421418_gene2322	1.289e-10	76.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,43U1H@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
WLSH3_k127_8469316_0	1379698.RBG1_1C00001G0201	1.208e-104	346.0	COG0714@1|root,COG0714@2|Bacteria,2NNV8@2323|unclassified Bacteria	2|Bacteria	O	ATPase family associated with various cellular activities (AAA)	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WLSH3_k127_8478036_0	880073.Calab_0453	2.973e-109	359.0	COG2812@1|root,COG2812@2|Bacteria,2NNK7@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WLSH3_k127_8478036_1	1379698.RBG1_1C00001G1362	2.042e-17	89.0	2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria	2|Bacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
WLSH3_k127_8480914_0	1123508.JH636439_gene478	1.817e-49	181.0	COG3542@1|root,COG3542@2|Bacteria,2J36N@203682|Planctomycetes	203682|Planctomycetes	S	Cupin superfamily (DUF985)	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_5
WLSH3_k127_8480914_1	1379270.AUXF01000005_gene669	2.038e-43	166.0	COG1776@1|root,COG1776@2|Bacteria,1ZTIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
WLSH3_k127_8480914_2	518766.Rmar_1776	3.743e-13	73.0	COG1309@1|root,COG1309@2|Bacteria,4NHIJ@976|Bacteroidetes	976|Bacteroidetes	K	TetR Family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WLSH3_k127_852827_0	1191523.MROS_1920	4.598e-184	582.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184	Gp_dh_C,Gp_dh_N
WLSH3_k127_852827_1	515635.Dtur_0901	1.952e-23	107.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
WLSH3_k127_8570536_3	234267.Acid_3666	1.879e-10	67.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
WLSH3_k127_8570536_1	1121405.dsmv_3563	4.047e-27	117.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2MKCX@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WLSH3_k127_8570536_0	1379698.RBG1_1C00001G1568	5.524e-106	353.0	COG0202@1|root,COG0202@2|Bacteria,2NNQQ@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WLSH3_k127_8570536_2	869210.Marky_1699	8.417e-11	63.0	COG0522@1|root,COG0522@2|Bacteria,1WINE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WLSH3_k127_8603914_2	646529.Desaci_4046	4.805e-12	78.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,2621N@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat region	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
WLSH3_k127_8603914_1	1519464.HY22_08670	2.02e-39	162.0	COG1555@1|root,COG1555@2|Bacteria,1FE73@1090|Chlorobi	1090|Chlorobi	L	photosystem II stabilization	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
WLSH3_k127_8603914_0	1379698.RBG1_1C00001G0400	1.098e-116	391.0	COG0206@1|root,COG0206@2|Bacteria,2NNSU@2323|unclassified Bacteria	2|Bacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WLSH3_k127_8647604_1	459349.CLOAM0891	1.667e-15	89.0	COG1520@1|root,COG4412@1|root,COG1520@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_2,HATPase_c,PQQ_2,PQQ_3,Peptidase_C25,SLH,Y_Y_Y
WLSH3_k127_8647604_0	1128421.JAGA01000003_gene2954	1.425e-75	272.0	COG2211@1|root,COG2211@2|Bacteria,2NR8E@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_8677661_4	706587.Desti_4010	1.072e-30	123.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2MQ5C@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WLSH3_k127_8677661_1	1232410.KI421412_gene110	7.108e-61	220.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WM9R@28221|Deltaproteobacteria,43S3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Putative RNA methylase family UPF0020	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_25,Methyltransf_31
WLSH3_k127_8677661_2	1150474.JQJI01000035_gene947	2.657e-40	151.0	COG3383@1|root,COG3383@2|Bacteria,2GDGJ@200918|Thermotogae	200918|Thermotogae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4
WLSH3_k127_8677661_0	868595.Desca_1314	9.454e-126	411.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,263DR@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WLSH3_k127_8677661_3	768710.DesyoDRAFT_3847	8.292e-37	141.0	COG1149@1|root,COG1149@2|Bacteria,1V4I0@1239|Firmicutes,24HMG@186801|Clostridia,26299@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH3_k127_8681378_2	1122603.ATVI01000007_gene1509	0.0001825	54.0	COG4932@1|root,COG5276@1|root,COG4932@2|Bacteria,COG5276@2|Bacteria,1R85W@1224|Proteobacteria	1224|Proteobacteria	M	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
WLSH3_k127_8681378_0	309807.SRU_1916	7.408e-19	101.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4PM65@976|Bacteroidetes,1FKEM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1
WLSH3_k127_8681378_1	515635.Dtur_1219	9.893e-06	50.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WLSH3_k127_873952_1	309807.SRU_0884	8.205e-63	228.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,4NEV7@976|Bacteroidetes,1FITV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
WLSH3_k127_873952_4	938278.CAJO01000078_gene1086	3.688e-26	117.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2683T@186813|unclassified Clostridiales	186801|Clostridia	KLT	Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH3_k127_873952_6	1408436.JHXY01000005_gene140	9.744e-19	95.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25VI6@186806|Eubacteriaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WLSH3_k127_873952_0	471223.GWCH70_1069	1.383e-68	247.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,1WE4J@129337|Geobacillus	91061|Bacilli	G	Ribulose-phosphate 3 epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WLSH3_k127_873952_2	767817.Desgi_3401	3.206e-55	198.0	COG1773@1|root,COG1853@1|root,COG1773@2|Bacteria,COG1853@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,266U0@186807|Peptococcaceae	186801|Clostridia	C	Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubredoxin
WLSH3_k127_873952_5	1121440.AUMA01000009_gene629	2.714e-25	105.0	COG1773@1|root,COG1773@2|Bacteria,1NES3@1224|Proteobacteria,42VN9@68525|delta/epsilon subdivisions,2WRT2@28221|Deltaproteobacteria,2MCJQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the rubredoxin family	-	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114	-	-	-	-	-	-	-	-	-	-	Rubredoxin
WLSH3_k127_873952_3	1150474.JQJI01000004_gene389	6.909e-32	126.0	COG0426@1|root,COG0426@2|Bacteria,2GCAS@200918|Thermotogae	200918|Thermotogae	C	flavodoxin nitric oxide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
WLSH3_k127_8787874_0	748247.AZKH_1848	2.879e-173	553.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KVB1@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
WLSH3_k127_8787874_2	1173029.JH980292_gene60	2.663e-36	146.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_1,TPR_11,TPR_2,TPR_8
WLSH3_k127_8787874_1	1304284.L21TH_2281	9.116e-122	404.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,36EGP@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
WLSH3_k127_8787874_3	1499967.BAYZ01000123_gene2518	1.811e-13	72.0	COG1598@1|root,COG1598@2|Bacteria,2NQ8D@2323|unclassified Bacteria	2|Bacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
WLSH3_k127_8793821_4	298386.PBPRA1244	2.365e-12	68.0	COG1051@1|root,COG1763@1|root,COG1051@2|Bacteria,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,1S72P@1236|Gammaproteobacteria,1XWZJ@135623|Vibrionales	135623|Vibrionales	H	Molybdopterin guanine dinucleotide synthesis protein B	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
WLSH3_k127_8793821_0	316274.Haur_0387	7.937e-97	330.0	COG0303@1|root,COG0303@2|Bacteria,2G6AK@200795|Chloroflexi,375EW@32061|Chloroflexia	32061|Chloroflexia	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WLSH3_k127_8793821_3	504728.K649_10275	1.483e-42	162.0	COG1943@1|root,COG1943@2|Bacteria,1WKUD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_8793821_1	1220534.B655_2238	8.736e-65	243.0	COG3839@1|root,arCOG00175@2157|Archaea,2Y7MB@28890|Euryarchaeota,23PKR@183925|Methanobacteria	183925|Methanobacteria	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
WLSH3_k127_8793821_2	323259.Mhun_0520	1.492e-53	195.0	COG4662@1|root,arCOG00166@2157|Archaea,2XTDY@28890|Euryarchaeota	28890|Euryarchaeota	P	ABC-type tungstate transport system, periplasmic component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
WLSH3_k127_8805305_3	321327.CYA_0846	4.819e-46	177.0	COG0177@1|root,COG0177@2|Bacteria,1GRH4@1117|Cyanobacteria,1H188@1129|Synechococcus	1117|Cyanobacteria	L	Base excision DNA repair protein, HhH-GPD family	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WLSH3_k127_8805305_2	1191523.MROS_2494	8.069e-59	216.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
WLSH3_k127_8805305_1	945713.IALB_0213	9.221e-72	256.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pimB_1	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WLSH3_k127_8805305_0	1379698.RBG1_1C00001G1037	2.668e-76	263.0	COG0463@1|root,COG0463@2|Bacteria,2NPA5@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 2	kdtX	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
WLSH3_k127_8805305_4	1125863.JAFN01000001_gene533	7.49e-40	158.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,43BK5@68525|delta/epsilon subdivisions,2X6Y1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH3_k127_8805305_5	1123400.KB904756_gene2689	3.972e-07	54.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,1RQUH@1236|Gammaproteobacteria,462H0@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH3_k127_8829891_0	1089553.Tph_c02250	9.7e-214	694.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,42EYT@68295|Thermoanaerobacterales	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WLSH3_k127_8858509_5	760568.Desku_0657	3.211e-24	106.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,2603C@186807|Peptococcaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WLSH3_k127_8858509_4	269799.Gmet_2886	1.322e-24	115.0	COG2227@1|root,COG2227@2|Bacteria,1QY93@1224|Proteobacteria,42VQY@68525|delta/epsilon subdivisions,2WRC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WLSH3_k127_8858509_0	1304880.JAGB01000001_gene547	1.476e-151	487.0	COG0454@1|root,COG0456@2|Bacteria,1TT30@1239|Firmicutes,24DE0@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH3_k127_8858509_3	1304885.AUEY01000002_gene348	2.954e-29	119.0	COG0389@1|root,COG0389@2|Bacteria,1NEMK@1224|Proteobacteria,42X8R@68525|delta/epsilon subdivisions,2WRT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Pathogenicity locus	-	-	-	-	-	-	-	-	-	-	-	-	Cdd1
WLSH3_k127_8858509_7	247490.KSU1_C0877	6.593e-19	89.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
WLSH3_k127_8858509_2	1343739.PAP_00125	2.099e-33	134.0	COG0716@1|root,arCOG00519@2157|Archaea,2XZ4A@28890|Euryarchaeota,24470@183968|Thermococci	183968|Thermococci	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
WLSH3_k127_8858509_1	926561.KB900617_gene1754	8.796e-109	373.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WAEK@53433|Halanaerobiales	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WLSH3_k127_8936875_0	1499967.BAYZ01000186_gene3978	7.438e-116	406.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,2NRA2@2323|unclassified Bacteria	2|Bacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Bac_surface_Ag,PD40
WLSH3_k127_8968604_2	864069.MicloDRAFT_00048220	3.472e-21	93.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,1JV41@119045|Methylobacteriaceae	28211|Alphaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WLSH3_k127_8968604_0	330214.NIDE1303	0.0	1313.0	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WLSH3_k127_8968604_1	1379698.RBG1_1C00001G1604	1.406e-68	234.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WLSH3_k127_8968696_1	880073.Calab_3750	2.548e-71	248.0	COG0272@1|root,COG0272@2|Bacteria,2NNSW@2323|unclassified Bacteria	2|Bacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972,ko:K10754	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	M00289,M00295	R00382	RC00005	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH3_k127_8968696_0	502025.Hoch_5972	4.92e-73	260.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,42ST6@68525|delta/epsilon subdivisions,2WPEM@28221|Deltaproteobacteria,2YWW2@29|Myxococcales	28221|Deltaproteobacteria	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WLSH3_k127_8994647_2	546269.HMPREF0389_00880	2.507e-05	46.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,25RCJ@186804|Peptostreptococcaceae	186801|Clostridia	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
WLSH3_k127_8994647_1	1229203.KI301992_gene1027	6.477e-15	77.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,3UWNT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
WLSH3_k127_8994647_0	574087.Acear_1431	8.69e-97	329.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WAED@53433|Halanaerobiales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
WLSH3_k127_9002769_2	373903.Hore_15950	3.249e-27	113.0	COG0778@1|root,COG0778@2|Bacteria,1V49Q@1239|Firmicutes,24IH8@186801|Clostridia	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WLSH3_k127_9002769_1	309799.DICTH_0368	6.057e-65	234.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_5
WLSH3_k127_9002769_0	925409.KI911562_gene1301	1.392e-141	466.0	COG0513@1|root,COG0513@2|Bacteria,4NEVI@976|Bacteroidetes,1INY6@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WLSH3_k127_9021384_3	1504823.CCMM01000007_gene672	2.575e-23	101.0	COG0809@1|root,COG0809@2|Bacteria,2NNWD@2323|unclassified Bacteria	2|Bacteria	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WLSH3_k127_9021384_1	909663.KI867150_gene2054	8.235e-93	317.0	COG2836@1|root,COG2836@2|Bacteria,1QVGG@1224|Proteobacteria,432GS@68525|delta/epsilon subdivisions,2WXZW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
WLSH3_k127_9021384_0	485916.Dtox_0333	8.428e-99	330.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,261C1@186807|Peptococcaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
WLSH3_k127_9043820_1	945713.IALB_1713	4.666e-08	56.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WLSH3_k127_9043820_0	518766.Rmar_0508	1.029e-131	437.0	COG2203@1|root,COG2204@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FJ5I@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	Sigma54_activat
WLSH3_k127_9096972_0	574087.Acear_1028	3.077e-114	379.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3WA8M@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WLSH3_k127_9096972_1	459349.CLOAM1221	1.749e-58	210.0	COG0283@1|root,COG0761@1|root,COG0283@2|Bacteria,COG0761@2|Bacteria,2NPCE@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	ispH	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009240,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042380,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046490,GO:0046939,GO:0046940,GO:0048037,GO:0050145,GO:0051186,GO:0051188,GO:0051536,GO:0051538,GO:0051540,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	1.17.7.4,2.5.1.19,2.7.4.25,6.3.2.1	ko:K00800,ko:K00945,ko:K02945,ko:K03527,ko:K03977,ko:K13799	ko00240,ko00400,ko00410,ko00770,ko00900,ko01100,ko01110,ko01130,ko01230,ko03010,map00240,map00400,map00410,map00770,map00900,map01100,map01110,map01130,map01230,map03010	M00022,M00052,M00096,M00119,M00178	R00158,R00512,R01665,R02473,R03460,R05884,R08210	RC00002,RC00096,RC00141,RC00350,RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011	-	-	iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iIT341.HP0400,iLJ478.TM1444,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024	Cytidylate_kin,LYTB
WLSH3_k127_9096972_3	1379698.RBG1_1C00001G1226	4.332e-39	153.0	COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria	2|Bacteria	I	Phosphate acyltransferases	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WLSH3_k127_9096972_2	1122216.AUHW01000038_gene259	1.014e-55	201.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,4H9D1@909932|Negativicutes	909932|Negativicutes	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
WLSH3_k127_9104046_1	161156.JQKW01000012_gene51	3.179e-33	132.0	COG0474@1|root,COG0474@2|Bacteria,2GGR5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
WLSH3_k127_9104046_0	123214.PERMA_1167	7.689e-149	484.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,2G3NC@200783|Aquificae	200783|Aquificae	I	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
WLSH3_k127_9105100_2	643867.Ftrac_0681	8.59e-07	55.0	2CIAQ@1|root,2ZXJG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9105100_0	289376.THEYE_A0983	5.812e-101	336.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
WLSH3_k127_9105100_1	880073.Calab_3071	2.508e-21	95.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,Flg_new,SLH
WLSH3_k127_9140415_0	1379698.RBG1_1C00001G0553	5.98e-104	348.0	COG1493@1|root,COG1493@2|Bacteria,2NP5B@2323|unclassified Bacteria	2|Bacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
WLSH3_k127_9140415_5	1408422.JHYF01000011_gene3470	7.124e-11	66.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,36I5Z@31979|Clostridiaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
WLSH3_k127_9140415_2	644282.Deba_2982	1.582e-83	291.0	COG0320@1|root,COG0321@1|root,COG0320@2|Bacteria,COG0321@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
WLSH3_k127_9140415_1	1121468.AUBR01000012_gene2580	8.203e-103	351.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,2480F@186801|Clostridia,42EW5@68295|Thermoanaerobacterales	186801|Clostridia	K	RNA polymerase sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WLSH3_k127_9140415_4	517418.Ctha_0792	1.429e-18	98.0	COG1452@1|root,COG1452@2|Bacteria,1FE6F@1090|Chlorobi	1090|Chlorobi	M	OstA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OstA_2
WLSH3_k127_9140415_6	908612.HMPREF9720_1558	5.37e-05	52.0	COG5373@1|root,COG5373@2|Bacteria,4PMZ8@976|Bacteroidetes,2G0MC@200643|Bacteroidia,22UJ0@171550|Rikenellaceae	976|Bacteroidetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
WLSH3_k127_9140415_3	1121904.ARBP01000011_gene1542	6.507e-31	126.0	COG1560@1|root,COG1560@2|Bacteria,4NQEF@976|Bacteroidetes	976|Bacteroidetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
WLSH3_k127_9170411_3	746697.Aeqsu_0488	5.834e-05	56.0	COG4409@1|root,COG4409@2|Bacteria,4NJCZ@976|Bacteroidetes,1I0GI@117743|Flavobacteriia	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
WLSH3_k127_9170411_2	880071.Fleli_1972	2.538e-05	57.0	COG3292@1|root,COG3292@2|Bacteria,4NDWE@976|Bacteroidetes,47M4V@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
WLSH3_k127_9170411_1	945713.IALB_2581	4.886e-18	94.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9170411_0	366602.Caul_4400	2.58e-35	138.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2UAEV@28211|Alphaproteobacteria,2KH50@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WLSH3_k127_9170411_4	751945.Theos_1058	6.446e-05	47.0	COG1959@1|root,COG1959@2|Bacteria,1WJXZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WLSH3_k127_9191469_0	880073.Calab_3729	1.247e-135	441.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WLSH3_k127_9191469_2	1089553.Tph_c26380	1.654e-36	146.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JKC@186801|Clostridia,42GW5@68295|Thermoanaerobacterales	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	3.1.3.3	ko:K22305	ko00260,ko00680,ko01100,ko01120,ko01130,map00260,map00680,map01100,map01120,map01130	-	R00582	RC00017	ko00000,ko00001,ko01000	-	-	-	His_Phos_1
WLSH3_k127_9191469_3	345341.KUTG_04957	2.761e-21	108.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria,4DZ35@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_10,TPR_12,TPR_7,TPR_8,Trans_reg_C
WLSH3_k127_9191469_1	1288484.APCS01000040_gene1731	8.119e-37	143.0	COG2217@1|root,COG2217@2|Bacteria,1WJ55@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	pacS	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH3_k127_9228024_7	869210.Marky_1601	5.729e-17	84.0	COG1436@1|root,COG1436@2|Bacteria,1WKHR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
WLSH3_k127_9228024_2	459349.CLOAM1198	4.541e-51	192.0	2ANS9@1|root,31DS7@2|Bacteria,2NQ66@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9228024_5	1379698.RBG1_1C00001G0113	6.392e-45	167.0	28MYQ@1|root,2ZB5K@2|Bacteria,2NPC8@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9228024_6	330214.NIDE2491	3.222e-19	91.0	28MYQ@1|root,2ZB5K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9228024_4	1379698.RBG1_1C00001G0118	4.088e-47	177.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9228024_0	1379698.RBG1_1C00001G0119	3.253e-78	270.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9228024_10	1379698.RBG1_1C00001G0119	1.254e-09	68.0	28MEN@1|root,2ZASA@2|Bacteria,2NQD3@2323|unclassified Bacteria	2|Bacteria	S	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9228024_3	593750.Metfor_0256	5.951e-49	188.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,2NAIS@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC-2	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
WLSH3_k127_9228024_9	751945.Theos_0818	1.876e-11	72.0	COG1390@1|root,COG1390@2|Bacteria,1WK58@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
WLSH3_k127_9228024_8	469381.Dpep_2223	4.449e-14	76.0	COG0636@1|root,COG0636@2|Bacteria,3TBJ8@508458|Synergistetes	508458|Synergistetes	C	ATP synthase, subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
WLSH3_k127_9228024_1	1041930.Mtc_1283	1.172e-58	215.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,2NAKS@224756|Methanomicrobia	224756|Methanomicrobia	C	V-type ATPase 116kDa subunit family	atpI-2	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
WLSH3_k127_9290539_1	1047013.AQSP01000142_gene242	2.471e-231	727.0	COG2511@1|root,COG2511@2|Bacteria	2|Bacteria	J	GatB/GatE catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GatB_N
WLSH3_k127_9290539_3	1450525.JATV01000008_gene674	7.076e-46	168.0	COG0614@1|root,COG0614@2|Bacteria,4NTHD@976|Bacteroidetes,1I4WB@117743|Flavobacteriia,2NWWP@237|Flavobacterium	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH3_k127_9290539_0	1047013.AQSP01000142_gene241	2.82e-248	771.0	COG0252@1|root,COG0252@2|Bacteria,2NPMK@2323|unclassified Bacteria	2|Bacteria	EJ	Asparaginase	ansA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
WLSH3_k127_9290539_2	269799.Gmet_3085	1.349e-77	288.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
WLSH3_k127_9320710_2	1232410.KI421412_gene285	1.689e-16	88.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
WLSH3_k127_9320710_1	46234.ANA_C10377	1.146e-39	158.0	COG0463@1|root,COG0463@2|Bacteria,1GQ7K@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WLSH3_k127_9320710_0	927677.ALVU02000001_gene3328	4.444e-73	254.0	COG0438@1|root,COG0438@2|Bacteria,1G1VE@1117|Cyanobacteria,1H6K2@1142|Synechocystis	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11
WLSH3_k127_9342023_5	411467.BACCAP_01138	2.665e-11	64.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,267Y0@186813|unclassified Clostridiales	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WLSH3_k127_9342023_2	671143.DAMO_2061	6.349e-67	234.0	COG2231@1|root,COG2231@2|Bacteria,2NR9H@2323|unclassified Bacteria	2|Bacteria	L	endonuclease III	magIII	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
WLSH3_k127_9342023_1	1122919.KB905583_gene3781	9.079e-111	368.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,26R39@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	drrA1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_9342023_3	324057.Pjdr2_0828	4.557e-54	205.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,26TCG@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter permease	M1-956	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH3_k127_9342023_4	635013.TherJR_1110	5.951e-54	199.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,24A3T@186801|Clostridia,262P1@186807|Peptococcaceae	186801|Clostridia	S	transport system permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WLSH3_k127_9342023_0	1379698.RBG1_1C00001G1860	1.438e-135	440.0	COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria	2|Bacteria	D	MreB/Mbl protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WLSH3_k127_9343265_0	316067.Geob_2761	1.387e-247	789.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WLSH3_k127_9391704_0	304371.MCP_0384	5.666e-218	696.0	COG2217@1|root,arCOG02763@1|root,arCOG01576@2157|Archaea,arCOG02763@2157|Archaea,2XT3T@28890|Euryarchaeota,2N94W@224756|Methanomicrobia	224756|Methanomicrobia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WLSH3_k127_941150_1	1200792.AKYF01000013_gene4109	1.585e-25	107.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,26R6I@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WLSH3_k127_941150_0	1379698.RBG1_1C00001G1366	1.773e-99	342.0	COG0577@1|root,COG0577@2|Bacteria,2NQMU@2323|unclassified Bacteria	2|Bacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH3_k127_941150_2	608538.HTH_0937	9.089e-24	108.0	COG0577@1|root,COG0577@2|Bacteria,2G3WT@200783|Aquificae	200783|Aquificae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH3_k127_941150_3	378806.STAUR_1087	1.468e-11	68.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WLSH3_k127_9477476_1	309801.trd_A0816	9.989e-75	262.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	189775|Thermomicrobia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WLSH3_k127_9477476_0	1120973.AQXL01000121_gene68	1.047e-77	271.0	COG0477@1|root,COG2814@2|Bacteria,1TPPY@1239|Firmicutes,4HNJ9@91061|Bacilli,27A8T@186823|Alicyclobacillaceae	91061|Bacilli	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WLSH3_k127_9478138_1	42256.RradSPS_3047	2.363e-31	128.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,4CPVZ@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WLSH3_k127_9478138_0	671143.DAMO_0390	6.877e-102	344.0	COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346,ko:K14161	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WLSH3_k127_9509867_0	634956.Geoth_0103	3.413e-148	479.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,1WFS2@129337|Geobacillus	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
WLSH3_k127_9509867_2	1395513.P343_00530	3.013e-16	85.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,4HKA1@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WLSH3_k127_9509867_1	1356852.N008_08320	1.93e-20	93.0	COG0614@1|root,COG0614@2|Bacteria,4NQYJ@976|Bacteroidetes,47XUE@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WLSH3_k127_9524119_3	768671.ThimaDRAFT_3639	4.99e-32	129.0	COG1129@1|root,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,1T1GD@1236|Gammaproteobacteria,1X2NV@135613|Chromatiales	135613|Chromatiales	G	ABC transporter	-	-	-	ko:K13926	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,ABC_tran
WLSH3_k127_9524119_0	646529.Desaci_2874	2.954e-192	611.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,2612Q@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
WLSH3_k127_9524119_1	1379698.RBG1_1C00001G0474	1.243e-138	455.0	COG0617@1|root,COG0617@2|Bacteria,2NPB4@2323|unclassified Bacteria	2|Bacteria	J	Poly A polymerase head domain	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WLSH3_k127_9524119_2	1379698.RBG1_1C00001G0345	2.542e-130	434.0	COG0342@1|root,COG0342@2|Bacteria,2NNNU@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH3_k127_9524119_4	1121405.dsmv_0963	3.059e-10	65.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2MI34@213118|Desulfobacterales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WLSH3_k127_9547216_3	264732.Moth_0883	8.247e-60	213.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia,42G12@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WLSH3_k127_9547216_7	1044.EH31_03565	1.355e-32	135.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2UBTC@28211|Alphaproteobacteria,2K5XU@204457|Sphingomonadales	204457|Sphingomonadales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
WLSH3_k127_9547216_2	316067.Geob_2780	1.318e-107	359.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WLSH3_k127_9547216_4	644282.Deba_2876	1.506e-56	206.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WLSH3_k127_9547216_6	1379698.RBG1_1C00001G0226	8.38e-48	192.0	COG1729@1|root,COG1729@2|Bacteria,2NPUR@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
WLSH3_k127_9547216_0	1379698.RBG1_1C00001G1511	3.481e-174	559.0	COG0312@1|root,COG0312@2|Bacteria,2NPIS@2323|unclassified Bacteria	2|Bacteria	S	Putative modulator of DNA gyrase	tldD2	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WLSH3_k127_9547216_5	596151.DesfrDRAFT_1284	1.775e-50	183.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,42T6V@68525|delta/epsilon subdivisions,2WPNI@28221|Deltaproteobacteria,2MC1S@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the peptidase S24 family	umuD	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
WLSH3_k127_9547216_1	1121448.DGI_0475	1.035e-107	358.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NJ4@68525|delta/epsilon subdivisions,2WJXN@28221|Deltaproteobacteria,2M84T@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	umuC	-	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
WLSH3_k127_9548361_5	716928.AJQT01000032_gene2736	1.269e-08	56.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,4BAZ6@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WLSH3_k127_9548361_3	1379698.RBG1_1C00001G0265	1.443e-80	282.0	COG0592@1|root,COG0592@2|Bacteria,2NP7D@2323|unclassified Bacteria	2|Bacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.7.7.7	ko:K02338,ko:K03610	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400,ko04812	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WLSH3_k127_9548361_0	880073.Calab_3531	1.254e-127	436.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	-	ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
WLSH3_k127_9548361_2	1183438.GKIL_0479	2.033e-103	346.0	COG0673@1|root,COG0673@2|Bacteria,1G1CZ@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WLSH3_k127_9548361_1	316274.Haur_3570	5.731e-111	379.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,2GAB0@200795|Chloroflexi,374U6@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD
WLSH3_k127_9548361_4	880073.Calab_3177	5.338e-10	72.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
WLSH3_k127_9597134_4	234267.Acid_1509	1.443e-17	96.0	COG4219@1|root,COG4219@2|Bacteria,3Y301@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
WLSH3_k127_9597134_3	1536772.R70723_02120	1.66e-21	101.0	COG0011@1|root,COG0011@2|Bacteria,1VAIR@1239|Firmicutes,4HP0G@91061|Bacilli,26Z2V@186822|Paenibacillaceae	91061|Bacilli	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385,Thiamine_BP
WLSH3_k127_9597134_0	246194.CHY_2199	1.135e-142	468.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WLSH3_k127_9597134_2	1121440.AUMA01000012_gene1404	3.548e-52	194.0	COG2199@1|root,COG2199@2|Bacteria,1NV1F@1224|Proteobacteria	1224|Proteobacteria	T	ggdef domain	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,GGDEF,PAS,PAS_3,dCache_1
WLSH3_k127_9597134_1	937777.Deipe_0674	4.51e-98	354.0	COG1473@1|root,COG1473@2|Bacteria,1WM7N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WLSH3_k127_9608856_2	242159.ABO99001	1.094e-06	59.0	COG3914@1|root,KOG4626@2759|Eukaryota,37IV9@33090|Viridiplantae,34GWN@3041|Chlorophyta	3041|Chlorophyta	GOT	O-linked N-acetylglucosamine transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_10,TPR_16,TPR_2,TPR_8
WLSH3_k127_9608856_0	1123511.KB905865_gene1775	7.432e-56	205.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H3KV@909932|Negativicutes	909932|Negativicutes	H	PFAM biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WLSH3_k127_9608856_1	262724.TT_C0814	5.482e-10	69.0	COG0745@1|root,COG0745@2|Bacteria,1WNER@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
WLSH3_k127_9732358_4	1379698.RBG1_1C00001G1656	1.559e-39	152.0	COG0653@1|root,COG0653@2|Bacteria,2NNRK@2323|unclassified Bacteria	2|Bacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WLSH3_k127_9732358_0	1379270.AUXF01000003_gene3895	1.016e-284	897.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WLSH3_k127_9732358_1	1511.CLOST_2053	1.73e-94	336.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WLSH3_k127_9732358_2	1379698.RBG1_1C00001G0997	2.343e-58	212.0	COG1216@1|root,COG1216@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	DUF4214,Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
WLSH3_k127_9732358_3	1379698.RBG1_1C00001G0996	8.944e-57	199.0	COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WLSH3_k127_981204_0	1379698.RBG1_1C00001G0881	2.435e-100	349.0	COG0860@1|root,COG0860@2|Bacteria,2NQ79@2323|unclassified Bacteria	2|Bacteria	M	Ami_3	amiA	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,GHL10,SpoIID
WLSH3_k127_981204_1	756499.Desde_3399	7.959e-83	290.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,2616Y@186807|Peptococcaceae	186801|Clostridia	S	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WLSH3_k127_9912489_1	1209989.TepiRe1_0669	9.545e-173	557.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,42F6C@68295|Thermoanaerobacterales	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WLSH3_k127_9912489_0	632292.Calhy_0824	3.461e-204	661.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,42F3U@68295|Thermoanaerobacterales	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
WLSH3_k127_9912489_2	891968.Anamo_0072	2.077e-54	200.0	COG0697@1|root,COG0697@2|Bacteria,3TAVN@508458|Synergistetes	508458|Synergistetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WLSH3_k127_9938236_0	357808.RoseRS_3096	2.433e-66	233.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi,375V4@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WLSH3_k127_9938236_2	1340493.JNIF01000004_gene858	1.365e-49	186.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WLSH3_k127_9938236_6	589865.DaAHT2_2443	9.736e-13	78.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WLSH3_k127_9938236_5	398767.Glov_1844	4.013e-18	94.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
WLSH3_k127_9938236_1	1125863.JAFN01000001_gene3329	1.286e-57	207.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,43CRY@68525|delta/epsilon subdivisions,2X7ZI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
WLSH3_k127_9938236_7	645991.Sgly_2287	3.494e-09	63.0	2ECY4@1|root,336V8@2|Bacteria,1VJG0@1239|Firmicutes,24SHD@186801|Clostridia	186801|Clostridia	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
WLSH3_k127_9938236_3	477974.Daud_0256	5.564e-44	164.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,261PA@186807|Peptococcaceae	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WLSH3_k127_9938236_4	596151.DesfrDRAFT_2449	7.054e-24	109.0	COG0535@1|root,COG0535@2|Bacteria,1PEYS@1224|Proteobacteria,42SNS@68525|delta/epsilon subdivisions,2X5H9@28221|Deltaproteobacteria,2MGR3@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
WLSH3_k127_9960428_5	1123389.ATXJ01000002_gene1536	2.471e-53	194.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1WIQ0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
WLSH3_k127_9960428_8	690850.Desaf_0246	1.456e-24	109.0	COG1246@1|root,COG1246@2|Bacteria,1R0RF@1224|Proteobacteria,43D0Y@68525|delta/epsilon subdivisions,2X88U@28221|Deltaproteobacteria,2MHDF@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM C_GCAxxG_C_C family protein	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
WLSH3_k127_9960428_6	1333998.M2A_0592	2.391e-44	165.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,4BQ3M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WLSH3_k127_9960428_11	997350.HMPREF9129_2103	0.0001651	44.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,22HJC@1570339|Peptoniphilaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WLSH3_k127_9960428_7	1009370.ALO_03431	3.174e-29	118.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4H4GK@909932|Negativicutes	909932|Negativicutes	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WLSH3_k127_9960428_3	653733.Selin_1758	1.554e-73	258.0	COG0052@1|root,COG0052@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WLSH3_k127_9960428_2	1089553.Tph_c11150	1.81e-74	254.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,42EMG@68295|Thermoanaerobacterales	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WLSH3_k127_9960428_0	443144.GM21_1487	6.102e-86	290.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WLSH3_k127_9960428_4	1347392.CCEZ01000043_gene351	4.359e-62	218.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,36E62@31979|Clostridiaceae	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WLSH3_k127_9960428_9	1232410.KI421418_gene2265	1.478e-17	83.0	COG1143@1|root,COG1143@2|Bacteria,1R0D0@1224|Proteobacteria,43CVK@68525|delta/epsilon subdivisions,2X83J@28221|Deltaproteobacteria,43VPI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WLSH3_k127_9960428_1	485916.Dtox_3207	2.617e-83	284.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,260D7@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WLSH3_k127_9960428_10	309807.SRU_1714	1.295e-07	57.0	COG4589@1|root,COG4589@2|Bacteria,4NIPM@976|Bacteroidetes,1FJBV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WLSH3_k127_9972820_0	1121127.JAFA01000004_gene1486	4.03e-51	196.0	COG0438@1|root,COG0438@2|Bacteria,1MVA7@1224|Proteobacteria,2VM0Z@28216|Betaproteobacteria,1K0MP@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WLSH3_k127_9972820_1	573064.Mefer_0516	4.411e-25	118.0	COG0859@1|root,arCOG09624@2157|Archaea	2157|Archaea	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WLSH3_k127_9986741_1	660470.Theba_2150	0.0001843	46.0	COG1765@1|root,COG1765@2|Bacteria,2GE9P@200918|Thermotogae	200918|Thermotogae	O	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
WLSH3_k127_9986741_0	1005048.CFU_0261	3.593e-248	789.0	COG1506@1|root,COG1506@2|Bacteria,1N75C@1224|Proteobacteria,2VPE6@28216|Betaproteobacteria,472S9@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WLSH3_k127_9989474_0	525904.Tter_0977	2.149e-207	658.0	COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria	2|Bacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iG2583_1286.G2583_0027,iPC815.YPO0475	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
## 1660 queries scanned
## Total time (seconds): 6.807193994522095
## Rate: 243.86 q/s