## Mon Mar 17 12:12:43 2025
## emapper-2.1.9
## /home/zhangkaihang/.conda/envs/eggnog-mapper/bin/emapper.py -i /home/zhangkaihang/metadata_analysis/metawrap/paddysoil/4paddy/bin4gtdbtk/WXD1_bin.13.fa -m mmseqs --itype genome -o WXD1_bin.13 --output_dir /home/zhangkaihang/metadata_analysis/eggnog-mapper/paddysoil/4paddy/WXD1_bin.13 --cpu 8
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WXD1_k127_1021418_9	443143.GM18_3945	7.474e-46	171.0	COG2010@1|root,COG2010@2|Bacteria,1P88Q@1224|Proteobacteria,43BRV@68525|delta/epsilon subdivisions,2X73R@28221|Deltaproteobacteria,43SNU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
WXD1_k127_1021418_0	861299.J421_3630	2.436e-221	723.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
WXD1_k127_1021418_2	1379270.AUXF01000003_gene3823	5.822e-174	557.0	COG5557@1|root,COG5557@2|Bacteria,1ZSN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
WXD1_k127_1021418_10	861299.J421_3628	1.011e-29	136.0	COG2010@1|root,COG2010@2|Bacteria,1ZTMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
WXD1_k127_1021418_11	379066.GAU_2033	2.976e-17	90.0	COG2010@1|root,COG2010@2|Bacteria,1ZTPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WXD1_k127_1021418_6	379066.GAU_2032	9.094e-63	232.0	COG5557@1|root,COG5557@2|Bacteria,1ZTCE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1021418_8	1499967.BAYZ01000100_gene3464	2.281e-57	209.0	COG0565@1|root,COG0565@2|Bacteria,2NQ39@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.200,3.5.1.19,6.1.1.16	ko:K01883,ko:K02533,ko:K08281,ko:K15396	ko00760,ko00970,ko01100,map00760,map00970,map01100	M00359,M00360	R01268,R03650	RC00055,RC00100,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	SpoU_methylase
WXD1_k127_1021418_4	243231.GSU2744	8.604e-120	399.0	COG0477@1|root,COG0477@2|Bacteria,1QWSX@1224|Proteobacteria,43C55@68525|delta/epsilon subdivisions,2X7FI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WXD1_k127_1021418_5	234267.Acid_5053	1.27e-113	381.0	COG0520@1|root,COG0520@2|Bacteria,3Y4TH@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_1021418_7	644282.Deba_0147	2.289e-60	224.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WPU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
WXD1_k127_1021418_3	945713.IALB_0608	3.433e-137	464.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
WXD1_k127_1021418_1	379066.GAU_0444	3.874e-185	595.0	COG0624@1|root,COG0624@2|Bacteria,1ZT2K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WXD1_k127_1023498_5	1028800.RG540_CH23730	3.686e-18	87.0	COG1125@1|root,COG1125@2|Bacteria,1QTUC@1224|Proteobacteria,2TTMA@28211|Alphaproteobacteria,4B7WM@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	ABC transporter	yehX	GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
WXD1_k127_1023498_2	1265313.HRUBRA_02839	2.664e-98	344.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,1RPSP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycine betaine	opuCC	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
WXD1_k127_1023498_3	649831.L083_6439	4.575e-31	122.0	COG5207@1|root,COG5207@2|Bacteria,2IKW9@201174|Actinobacteria,4DMMN@85008|Micromonosporales	201174|Actinobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
WXD1_k127_1023498_1	1174528.JH992898_gene938	7.675e-122	402.0	28HGI@1|root,2Z7SC@2|Bacteria,1FZZQ@1117|Cyanobacteria,1JHV5@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1023498_0	861299.J421_6151	1.104e-193	624.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	MA20_16100	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
WXD1_k127_1023498_4	861299.J421_1498	6.536e-27	115.0	2EDH2@1|root,337D5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1023498_6	1166018.FAES_3686	5.585e-18	83.0	COG2195@1|root,COG2195@2|Bacteria,4NE7N@976|Bacteroidetes,47K1G@768503|Cytophagia	976|Bacteroidetes	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WXD1_k127_1031730_4	1379270.AUXF01000001_gene2386	7.761e-30	123.0	COG1896@1|root,COG1896@2|Bacteria,1ZU77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
WXD1_k127_1031730_5	448385.sce2954	5.233e-21	98.0	COG0784@1|root,COG0784@2|Bacteria,1N7IK@1224|Proteobacteria,42VBR@68525|delta/epsilon subdivisions,2WRA1@28221|Deltaproteobacteria,2Z0IT@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WXD1_k127_1031730_2	1223523.H340_09885	3.292e-72	265.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WXD1_k127_1031730_0	215803.DB30_0865	1.095e-99	340.0	COG1172@1|root,COG1172@2|Bacteria,1MUDF@1224|Proteobacteria,439IX@68525|delta/epsilon subdivisions,2X4VD@28221|Deltaproteobacteria,2YZPC@29|Myxococcales	28221|Deltaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WXD1_k127_1031730_1	926550.CLDAP_26080	1.069e-96	335.0	COG1879@1|root,COG1879@2|Bacteria,2G97E@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
WXD1_k127_1031730_3	1379270.AUXF01000001_gene2542	1.781e-52	189.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WXD1_k127_1037755_1	161528.ED21_23756	7.418e-12	76.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2U31V@28211|Alphaproteobacteria,2K3PY@204457|Sphingomonadales	204457|Sphingomonadales	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1037755_2	378806.STAUR_3724	2.613e-10	74.0	2AIWV@1|root,319EH@2|Bacteria,1Q2HT@1224|Proteobacteria,433TN@68525|delta/epsilon subdivisions,2X3EP@28221|Deltaproteobacteria,2YVQT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1037755_0	1192034.CAP_0163	1.534e-30	138.0	COG3303@1|root,COG3303@2|Bacteria,1MYBV@1224|Proteobacteria,42SER@68525|delta/epsilon subdivisions,2WPC2@28221|Deltaproteobacteria,2YUR5@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
WXD1_k127_1049691_0	1121104.AQXH01000004_gene112	1.121e-05	57.0	COG4726@1|root,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	DUF4900,PilX_N
WXD1_k127_1052714_11	710111.FraQA3DRAFT_4065	9.119e-12	77.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	echA12_1	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WXD1_k127_1052714_2	292459.STH720	6.447e-156	502.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WXD1_k127_1052714_1	886293.Sinac_5995	4.918e-170	559.0	COG1012@1|root,COG1012@2|Bacteria,2IXQ2@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WXD1_k127_1052714_6	1379698.RBG1_1C00001G0806	1.611e-109	361.0	COG1024@1|root,COG1024@2|Bacteria,2NPAC@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
WXD1_k127_1052714_9	1125863.JAFN01000001_gene2929	8.314e-31	129.0	COG1309@1|root,COG1309@2|Bacteria,1N9ZB@1224|Proteobacteria,42VC2@68525|delta/epsilon subdivisions,2WRA9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WXD1_k127_1052714_7	1254432.SCE1572_19815	6.301e-93	323.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2YZNI@29|Myxococcales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
WXD1_k127_1052714_4	1460640.JCM19046_2528	8.305e-125	414.0	COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,4HAIX@91061|Bacilli,1ZD1V@1386|Bacillus	91061|Bacilli	S	UPF0365 protein	yqfA	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
WXD1_k127_1052714_5	861299.J421_0829	1.636e-121	406.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GAF,HTH_8,Sigma54_activat
WXD1_k127_1052714_12	47716.JOFH01000027_gene3112	1.241e-06	60.0	COG0457@1|root,COG1672@1|root,COG3629@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG3629@2|Bacteria,2H1NS@201174|Actinobacteria	201174|Actinobacteria	K	DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,NB-ARC,TPR_12,TPR_7,Trans_reg_C
WXD1_k127_1052714_3	562970.Btus_2368	7.041e-132	430.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli,278TC@186823|Alicyclobacillaceae	91061|Bacilli	C	Citrate synthase, C-terminal domain	citZ	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WXD1_k127_1052714_0	861299.J421_3325	4.068e-186	589.0	COG0538@1|root,COG0538@2|Bacteria	2|Bacteria	C	isocitrate dehydrogenase activity	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
WXD1_k127_1067494_1	379066.GAU_1124	5.747e-127	416.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WXD1_k127_1067494_11	861299.J421_2889	4.197e-29	128.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WXD1_k127_1067494_9	1160707.AJIK01000010_gene2472	1.319e-36	151.0	COG3677@1|root,COG3677@2|Bacteria,1TTUH@1239|Firmicutes,4IDU8@91061|Bacilli,26I08@186818|Planococcaceae	91061|Bacilli	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
WXD1_k127_1067494_7	1120973.AQXL01000116_gene322	1.289e-45	178.0	COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,4HEHP@91061|Bacilli,2797U@186823|Alicyclobacillaceae	91061|Bacilli	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
WXD1_k127_1067494_3	861299.J421_2888	3.422e-100	345.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
WXD1_k127_1067494_8	379066.GAU_1117	5.873e-45	178.0	COG0558@1|root,COG0558@2|Bacteria,1ZSXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WXD1_k127_1067494_4	379066.GAU_1116	2.95e-89	297.0	COG1100@1|root,COG1100@2|Bacteria,1ZSQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
WXD1_k127_1067494_10	379066.GAU_1115	4.087e-32	131.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
WXD1_k127_1067494_14	861299.J421_2884	5.4e-14	76.0	29142@1|root,2ZNRG@2|Bacteria,1ZV6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1067494_5	1379270.AUXF01000005_gene387	1.074e-70	259.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
WXD1_k127_1067494_12	861299.J421_2882	2.42e-25	109.0	COG0718@1|root,COG0718@2|Bacteria,1ZU1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
WXD1_k127_1067494_13	340177.Cag_1992	5.178e-16	87.0	COG0792@1|root,COG0792@2|Bacteria,1FE8E@1090|Chlorobi	1090|Chlorobi	J	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
WXD1_k127_1067494_2	204669.Acid345_3265	5.485e-104	352.0	COG0451@1|root,COG0451@2|Bacteria,3Y3CF@57723|Acidobacteria,2JI4M@204432|Acidobacteriia	204432|Acidobacteriia	M	Polysaccharide biosynthesis protein	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
WXD1_k127_1067494_0	861299.J421_0858	1.986e-138	473.0	COG1596@1|root,COG1596@2|Bacteria,1ZUC0@142182|Gemmatimonadetes	2|Bacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
WXD1_k127_1067494_6	861299.J421_4103	6.959e-62	241.0	COG0515@1|root,COG5184@1|root,COG0515@2|Bacteria,COG5184@2|Bacteria,1ZUHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	DKLTZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RCC1
WXD1_k127_1075210_10	1120950.KB892770_gene1365	2.227e-25	117.0	COG1408@1|root,COG1408@2|Bacteria,2I2EP@201174|Actinobacteria,4DU6W@85009|Propionibacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WXD1_k127_1075210_3	861299.J421_2921	3.422e-61	222.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WXD1_k127_1075210_1	861299.J421_0690	9.478e-72	246.0	2AYX9@1|root,31R2Z@2|Bacteria,1ZTNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_1075210_13	223283.PSPTO_0807	1.218e-18	92.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1Z77N@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WXD1_k127_1075210_5	243090.RB974	5.125e-54	196.0	COG1671@1|root,COG1671@2|Bacteria,2IZRB@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
WXD1_k127_1075210_14	861299.J421_2367	2.952e-11	74.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1075210_0	365046.Rta_24050	1.634e-215	682.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,4A9MU@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM aminotransferase, class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WXD1_k127_1075210_4	216596.RL2803	2.772e-60	220.0	COG0500@1|root,COG0500@2|Bacteria,1REJ2@1224|Proteobacteria,2U7T5@28211|Alphaproteobacteria,4B9R4@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WXD1_k127_1075210_9	861299.J421_1459	3.528e-29	119.0	2EAHU@1|root,334M0@2|Bacteria,1ZV5S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1075210_6	234267.Acid_0571	2.911e-51	186.0	COG0346@1|root,COG0346@2|Bacteria,3Y85T@57723|Acidobacteria	57723|Acidobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WXD1_k127_1075210_11	935548.KI912159_gene5601	5.994e-25	119.0	2AFVV@1|root,315YK@2|Bacteria,1NQAN@1224|Proteobacteria,2UNGW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1075210_7	1219031.BBJR01000040_gene2707	2.905e-46	179.0	COG3768@1|root,COG3768@2|Bacteria,1NNZU@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697
WXD1_k127_1075210_12	404589.Anae109_0097	8.168e-22	108.0	298JI@1|root,2ZVQE@2|Bacteria,1P8JU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1075210_2	675635.Psed_6033	8.302e-65	224.0	COG3631@1|root,COG3631@2|Bacteria,2GR1G@201174|Actinobacteria,4EDKX@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WXD1_k127_1075210_8	1237149.C900_05014	8.81e-30	134.0	2DQF9@1|root,336H4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1075210_15	394221.Mmar10_0409	1.112e-07	61.0	2EF0I@1|root,338TM@2|Bacteria,1NHRK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1097935_5	1121920.AUAU01000005_gene951	7.606e-12	72.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
WXD1_k127_1097935_4	44060.JODL01000044_gene4005	4.277e-21	101.0	COG0526@1|root,COG0526@2|Bacteria,2GP7J@201174|Actinobacteria	201174|Actinobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WXD1_k127_1097935_3	1337093.MBE-LCI_0227	5.791e-25	111.0	COG1917@1|root,COG1917@2|Bacteria,1MZF9@1224|Proteobacteria,2U63E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_7,DUF4437
WXD1_k127_1097935_0	981383.AEWH01000012_gene3871	6.871e-152	499.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,4HCNK@91061|Bacilli	91061|Bacilli	D	sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SPOR,SpoIID
WXD1_k127_1097935_2	390989.JOEG01000016_gene5611	1.096e-74	270.0	COG1721@1|root,COG1721@2|Bacteria,2I9E2@201174|Actinobacteria,4DA7C@85008|Micromonosporales	201174|Actinobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WXD1_k127_1097935_1	390989.JOEG01000016_gene5612	8.219e-125	409.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DAWH@85008|Micromonosporales	201174|Actinobacteria	S	ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
WXD1_k127_1097935_6	1449069.JMLO01000033_gene51	0.0001865	53.0	2ESVE@1|root,33KDT@2|Bacteria,2I8VG@201174|Actinobacteria,4FUNY@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
WXD1_k127_11138_1	272134.KB731324_gene4437	3.828e-24	111.0	2BHGT@1|root,32BIY@2|Bacteria,1G5HV@1117|Cyanobacteria,1HAUR@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF2927)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2927
WXD1_k127_11138_0	861299.J421_4366	0.0	1122.0	COG1629@1|root,COG4771@2|Bacteria,1ZT7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WXD1_k127_1128376_5	1346791.M529_00995	2.397e-23	107.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	glucose sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
WXD1_k127_1128376_3	926569.ANT_10890	2.01e-61	218.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
WXD1_k127_1128376_0	240015.ACP_0267	1.148e-154	516.0	COG1331@1|root,COG1331@2|Bacteria,3Y3AA@57723|Acidobacteria,2JISJ@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
WXD1_k127_1128376_2	379066.GAU_0535	6.949e-78	267.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WXD1_k127_1128376_1	861299.J421_2444	1.408e-149	492.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1ZTG4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase alpha chain like domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5
WXD1_k127_1128376_4	649638.Trad_0709	4.175e-25	116.0	COG3824@1|root,COG3824@2|Bacteria,1WJSP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
WXD1_k127_1128376_6	1056816.JAFQ01000004_gene5590	1.157e-17	86.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria,4G1IK@85025|Nocardiaceae	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
WXD1_k127_1129859_0	1379270.AUXF01000002_gene1557	4.222e-204	655.0	COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_113596_17	742743.HMPREF9453_00655	0.0001822	52.0	COG0810@1|root,COG0810@2|Bacteria,1VDCH@1239|Firmicutes,4H54A@909932|Negativicutes	909932|Negativicutes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WXD1_k127_113596_13	1158760.AQXP01000031_gene894	4.561e-20	100.0	COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
WXD1_k127_113596_14	565045.NOR51B_243	6.708e-12	78.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	lipopolysaccharide heptosyltransferase I	rfaC	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	iB21_1397.B21_03429,iECBD_1354.ECBD_0105,iECB_1328.ECB_03478,iECD_1391.ECD_03478,iECNA114_1301.ECNA114_3774,iECSF_1327.ECSF_3456,iSF_1195.SF3661,iS_1188.S4107	Glyco_transf_9
WXD1_k127_113596_6	861299.J421_3870	7.695e-61	217.0	COG0859@1|root,COG0859@2|Bacteria,1ZT3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WXD1_k127_113596_1	379066.GAU_0638	9.812e-167	543.0	COG0745@1|root,COG0745@2|Bacteria,1ZTEW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PglZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PglZ,Response_reg
WXD1_k127_113596_2	379066.GAU_0639	1.258e-140	479.0	COG1132@1|root,COG1132@2|Bacteria,1ZT2T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
WXD1_k127_113596_4	861299.J421_0477	1.396e-106	359.0	COG0859@1|root,COG0859@2|Bacteria,1ZT3G@142182|Gemmatimonadetes	2|Bacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	opsX	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K02841,ko:K02843,ko:K02849,ko:K12982	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WXD1_k127_113596_12	269798.CHU_0701	2.417e-30	125.0	COG0614@1|root,COG0614@2|Bacteria,4NQ88@976|Bacteroidetes,47QDM@768503|Cytophagia	976|Bacteroidetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WXD1_k127_113596_16	639030.JHVA01000001_gene287	3.883e-07	62.0	COG4641@1|root,COG4641@2|Bacteria,3Y68E@57723|Acidobacteria,2JKCU@204432|Acidobacteriia	204432|Acidobacteriia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
WXD1_k127_113596_11	1125863.JAFN01000001_gene535	2.879e-33	148.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_113596_5	379066.GAU_2095	1.71e-65	235.0	COG1560@1|root,COG1560@2|Bacteria,1ZSTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
WXD1_k127_113596_8	861299.J421_2674	1.64e-51	202.0	COG0463@1|root,COG0463@2|Bacteria,1ZTJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	Glycos_transf_2
WXD1_k127_113596_7	1379270.AUXF01000005_gene516	1.05e-57	216.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
WXD1_k127_113596_3	861299.J421_2672	4.223e-121	398.0	COG1899@1|root,COG1899@2|Bacteria	2|Bacteria	O	peptidyl-lysine modification to peptidyl-hypusine	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_113596_9	439235.Dalk_2390	3.026e-49	187.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,2MJE6@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WXD1_k127_113596_0	356851.JOAN01000011_gene5572	1.568e-214	687.0	COG2304@1|root,COG3537@1|root,COG2304@2|Bacteria,COG3537@2|Bacteria,2GKPD@201174|Actinobacteria,4DA90@85008|Micromonosporales	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
WXD1_k127_113596_15	406124.ACPC01000019_gene2815	2.634e-11	76.0	2E6HR@1|root,33150@2|Bacteria,1VF6G@1239|Firmicutes,4IR8Y@91061|Bacilli,1ZKDM@1386|Bacillus	91061|Bacilli	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
WXD1_k127_113596_10	1193181.BN10_50002	2.532e-46	191.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria	201174|Actinobacteria	M	PFAM peptidase M6, immune inhibitor A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
WXD1_k127_114185_1	861299.J421_3988	7.962e-105	363.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
WXD1_k127_114185_0	379066.GAU_2525	3.13e-180	578.0	COG2204@1|root,COG2204@2|Bacteria,1ZSRQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_114185_2	1303518.CCALI_00571	2.388e-84	293.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WXD1_k127_114185_4	745310.G432_09530	2.419e-34	148.0	COG0500@1|root,COG0500@2|Bacteria,1QUSR@1224|Proteobacteria,2U78U@28211|Alphaproteobacteria,2K1PP@204457|Sphingomonadales	204457|Sphingomonadales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WXD1_k127_114185_3	575540.Isop_0468	2.388e-45	177.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,2J55B@203682|Planctomycetes	203682|Planctomycetes	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WXD1_k127_1175848_9	944480.ATUV01000001_gene765	1.645e-30	123.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,42MAU@68525|delta/epsilon subdivisions,2WK22@28221|Deltaproteobacteria,2M6B5@213113|Desulfurellales	28221|Deltaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
WXD1_k127_1175848_0	861299.J421_3747	4.096e-156	509.0	COG1197@1|root,COG1197@2|Bacteria,1ZT88@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WXD1_k127_1175848_10	667014.Thein_1029	2.125e-28	130.0	COG0760@1|root,COG0760@2|Bacteria,2GHMC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
WXD1_k127_1175848_7	1379270.AUXF01000003_gene3700	6.123e-38	160.0	COG0760@1|root,COG0760@2|Bacteria,1ZSU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
WXD1_k127_1175848_1	861299.J421_3744	2.605e-93	316.0	COG1995@1|root,COG1995@2|Bacteria,1ZT2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
WXD1_k127_1175848_2	379066.GAU_2160	7.236e-82	281.0	COG2884@1|root,COG2884@2|Bacteria,1ZTHQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WXD1_k127_1175848_4	379066.GAU_2161	2.527e-58	215.0	COG2177@1|root,COG2177@2|Bacteria,1ZTDR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Part of the ABC transporter FtsEX involved in	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
WXD1_k127_1175848_6	1379270.AUXF01000003_gene3684	3.826e-53	211.0	COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WXD1_k127_1175848_3	861299.J421_3797	3.637e-60	233.0	COG0470@1|root,COG0470@2|Bacteria,1ZT21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
WXD1_k127_1175848_5	1247963.JPHU01000013_gene627	3.709e-55	197.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
WXD1_k127_1175848_8	861299.J421_3799	7.312e-33	138.0	COG0741@1|root,COG0741@2|Bacteria,1ZTV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WXD1_k127_1228076_13	292459.STH507	1.751e-38	152.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WXD1_k127_1228076_12	713586.KB900536_gene189	1.009e-41	157.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria,1WYPB@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
WXD1_k127_1228076_15	861299.J421_3464	1.238e-33	136.0	COG1610@1|root,COG1610@2|Bacteria,1ZTS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
WXD1_k127_1228076_0	1395513.P343_01850	7.625e-133	452.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli,26NJC@186821|Sporolactobacillaceae	91061|Bacilli	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WXD1_k127_1228076_2	379066.GAU_1891	2.89e-117	393.0	COG0358@1|root,COG0358@2|Bacteria,1ZSTR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
WXD1_k127_1228076_18	1305737.JAFX01000001_gene1451	4.283e-12	75.0	COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,47JBK@768503|Cytophagia	976|Bacteroidetes	S	Zn-ribbon protein, possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
WXD1_k127_1228076_1	518766.Rmar_2564	1.672e-124	421.0	COG0608@1|root,COG0608@2|Bacteria,4NDW1@976|Bacteroidetes,1FJ1M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WXD1_k127_1228076_11	861299.J421_3458	2.833e-46	176.0	COG0742@1|root,COG0742@2|Bacteria,1ZTVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
WXD1_k127_1228076_8	1123367.C666_07650	1.219e-51	189.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,2KW7T@206389|Rhodocyclales	206389|Rhodocyclales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WXD1_k127_1228076_4	1379270.AUXF01000006_gene74	2.271e-100	338.0	COG0280@1|root,COG0280@2|Bacteria,1ZT01@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
WXD1_k127_1228076_9	861299.J421_3455	6.569e-50	181.0	COG1366@1|root,COG1366@2|Bacteria,1ZTXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
WXD1_k127_1228076_16	880071.Fleli_1133	3.761e-21	99.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes,47QUX@768503|Cytophagia	976|Bacteroidetes	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
WXD1_k127_1228076_5	861299.J421_3453	5.179e-88	312.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1ZSPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
WXD1_k127_1228076_10	1049564.TevJSym_aa00390	6.005e-49	188.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1J4UT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WXD1_k127_1228076_17	861299.J421_0489	4.739e-13	79.0	COG0642@1|root,COG3614@1|root,COG2205@2|Bacteria,COG3614@2|Bacteria	2|Bacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_1228076_7	379066.GAU_1881	2.859e-62	221.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WXD1_k127_1228076_6	1121129.KB903359_gene2218	6.872e-83	293.0	COG2235@1|root,COG2235@2|Bacteria,4NHKZ@976|Bacteroidetes,2FRKB@200643|Bacteroidia	976|Bacteroidetes	E	Amidinotransferase	-	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
WXD1_k127_1228076_14	1124780.ANNU01000059_gene847	2.65e-36	148.0	COG2176@1|root,COG2176@2|Bacteria,4PM8C@976|Bacteroidetes,47Y1H@768503|Cytophagia	976|Bacteroidetes	L	EXOIII	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T
WXD1_k127_1228076_3	861299.J421_3449	1.453e-106	361.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WXD1_k127_1230273_0	521674.Plim_1475	1.327e-67	238.0	COG0730@1|root,COG0730@2|Bacteria,2IZGZ@203682|Planctomycetes	203682|Planctomycetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WXD1_k127_1230273_2	1191523.MROS_1014	0.0001562	54.0	2EHX5@1|root,33BNR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1230273_1	546274.EIKCOROL_02651	9.438e-33	138.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,2KPSU@206351|Neisseriales	206351|Neisseriales	C	prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
WXD1_k127_1235621_4	1121428.DESHY_40085___1	0.0001409	52.0	COG5662@1|root,COG5662@2|Bacteria,1U216@1239|Firmicutes,25N56@186801|Clostridia,2631J@186807|Peptococcaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
WXD1_k127_1235621_2	861299.J421_3908	1.203e-73	254.0	COG1595@1|root,COG1595@2|Bacteria,1ZT3B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_1235621_3	861299.J421_3907	6.054e-70	247.0	COG0500@1|root,COG2226@2|Bacteria,1ZSNE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
WXD1_k127_1235621_0	1121468.AUBR01000021_gene2824	2.674e-221	714.0	COG3280@1|root,COG3280@2|Bacteria,1UERK@1239|Firmicutes,25JR7@186801|Clostridia,42HXY@68295|Thermoanaerobacterales	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	5.4.99.15	ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R09995	-	ko00000,ko00001,ko00002,ko01000	-	GH13	-	Alpha-amylase
WXD1_k127_1235621_1	326427.Cagg_2093	2.863e-114	381.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,3768X@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
WXD1_k127_1242489_0	926569.ANT_19710	1.64e-77	265.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WXD1_k127_1242489_1	1123508.JH636441_gene3431	2.5e-45	181.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
WXD1_k127_1244297_12	1340493.JNIF01000004_gene269	1.587e-15	78.0	COG0331@1|root,COG0331@2|Bacteria,3Y2TE@57723|Acidobacteria	57723|Acidobacteria	I	malonyl CoA-acyl carrier protein transacylase	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WXD1_k127_1244297_4	861299.J421_3272	8.075e-127	413.0	COG0332@1|root,COG0332@2|Bacteria,1ZSP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WXD1_k127_1244297_5	760568.Desku_2298	3.163e-91	312.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,2610G@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WXD1_k127_1244297_11	1158318.ATXC01000001_gene18	8.756e-16	78.0	COG0333@1|root,COG0333@2|Bacteria,2G4C1@200783|Aquificae	200783|Aquificae	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WXD1_k127_1244297_10	861299.J421_3275	9.181e-22	101.0	COG1399@1|root,COG1399@2|Bacteria,1ZTSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
WXD1_k127_1244297_9	379066.GAU_1643	1.839e-44	185.0	COG0105@1|root,COG0105@2|Bacteria,1ZTTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NDK	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WXD1_k127_1244297_7	861299.J421_3277	1.2e-50	190.0	COG0517@1|root,COG1762@1|root,COG0517@2|Bacteria,COG1762@2|Bacteria,1ZUGZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	CBS,PTS_EIIA_2
WXD1_k127_1244297_3	1379270.AUXF01000006_gene246	8.402e-144	460.0	COG0074@1|root,COG0074@2|Bacteria,1ZT20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
WXD1_k127_1244297_0	861299.J421_3279	1.012e-158	508.0	COG0045@1|root,COG0045@2|Bacteria,1ZSZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
WXD1_k127_1244297_6	880073.Calab_0632	1.242e-84	298.0	COG0549@1|root,COG0549@2|Bacteria,2NNKM@2323|unclassified Bacteria	2|Bacteria	E	Amino acid kinase family	arcC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3652,iE2348C_1286.E2348C_0454,iECABU_c1320.ECABU_c31550,iECED1_1282.ECED1_0540,iECED1_1282.ECED1_3334,iECIAI39_1322.ECIAI39_3289,iECNA114_1301.ECNA114_2915,iECOK1_1307.ECOK1_3260,iECS88_1305.ECS88_3153,iECSF_1327.ECSF_2670,iECUMN_1333.ECUMN_0561,iEcE24377_1341.EcE24377A_0559,iG2583_1286.G2583_0641,iHN637.CLJU_RS13830,iJN746.PP_0999,iUMN146_1321.UM146_02150,iUTI89_1310.UTI89_C3259,ic_1306.c3452	AA_kinase
WXD1_k127_1244297_2	349161.Dred_1797	6.888e-145	499.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,260EY@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0182	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
WXD1_k127_1244297_1	861299.J421_3281	1.013e-147	481.0	COG1109@1|root,COG1109@2|Bacteria,1ZSP6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WXD1_k127_1244297_8	247490.KSU1_D0315	9.078e-46	173.0	COG1007@1|root,COG1007@2|Bacteria,2IXC6@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
WXD1_k127_1258765_1	472759.Nhal_2659	9.898e-106	350.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria,1X0JQ@135613|Chromatiales	135613|Chromatiales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1258765_0	518766.Rmar_1357	5.51e-111	372.0	COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_1258765_2	221288.JH992901_gene1227	1.506e-40	168.0	COG3393@1|root,COG3393@2|Bacteria,1G551@1117|Cyanobacteria,1JJ54@1189|Stigonemataceae	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,FR47
WXD1_k127_1258765_3	448385.sce9292	2.972e-21	104.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria	1224|Proteobacteria	I	the in vivo substrate is	bmrU	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WXD1_k127_1265975_0	1429046.RR21198_2410	7.648e-225	715.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4FU6V@85025|Nocardiaceae	201174|Actinobacteria	L	ABC transporter	uvrA2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WXD1_k127_1265975_2	1082933.MEA186_18762	8.105e-52	204.0	COG0346@1|root,COG0346@2|Bacteria,1RIAM@1224|Proteobacteria,2U9TG@28211|Alphaproteobacteria,43MEK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WXD1_k127_1265975_1	1123320.KB889704_gene9398	2.423e-96	323.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_1265975_4	1380390.JIAT01000013_gene64	6.583e-43	164.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria,4CQ9B@84995|Rubrobacteria	84995|Rubrobacteria	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
WXD1_k127_1265975_3	1382359.JIAL01000001_gene205	1.099e-46	184.0	COG1125@1|root,COG1125@2|Bacteria,3Y4S7@57723|Acidobacteria,2JIFP@204432|Acidobacteriia	204432|Acidobacteriia	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
WXD1_k127_1270583_0	1379270.AUXF01000004_gene3318	2.766e-70	248.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1ZSP0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	DM	Chain length determinant protein	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	GNVR
WXD1_k127_1270583_2	395494.Galf_0122	5.699e-16	91.0	COG1639@1|root,COG2199@1|root,COG1639@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VHDQ@28216|Betaproteobacteria,44VWQ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HDOD,Response_reg
WXD1_k127_1270583_1	861299.J421_2496	1.093e-25	117.0	COG1596@1|root,COG1596@2|Bacteria,1ZTXZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	polysaccharide export	-	-	-	-	-	-	-	-	-	-	-	-	SLBB
WXD1_k127_1275506_0	525904.Tter_0551	1.686e-91	313.0	COG3294@1|root,COG3294@2|Bacteria,2NR9E@2323|unclassified Bacteria	2|Bacteria	S	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
WXD1_k127_1275506_3	215803.DB30_2099	1.423e-32	131.0	COG1801@1|root,COG1801@2|Bacteria,1N4QE@1224|Proteobacteria,42PDW@68525|delta/epsilon subdivisions,2WK6H@28221|Deltaproteobacteria,2YVUI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WXD1_k127_1275506_1	1157490.EL26_16980	2.824e-59	215.0	COG0584@1|root,COG0584@2|Bacteria,1TQ3Y@1239|Firmicutes,4HAI9@91061|Bacilli,279TU@186823|Alicyclobacillaceae	91061|Bacilli	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WXD1_k127_1275506_2	877414.ATWA01000004_gene599	1.075e-39	160.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,268A3@186813|unclassified Clostridiales	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
WXD1_k127_1282356_1	1128421.JAGA01000003_gene2811	5.787e-141	458.0	COG0498@1|root,COG0498@2|Bacteria,2NP42@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WXD1_k127_1282356_3	861299.J421_3049	1.873e-30	124.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
WXD1_k127_1282356_4	1121087.AUCK01000008_gene2310	1.183e-13	76.0	COG0694@1|root,COG0694@2|Bacteria,1UNSR@1239|Firmicutes,4IUP3@91061|Bacilli	91061|Bacilli	O	Scaffold protein Nfu/NifU N terminal	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N
WXD1_k127_1282356_5	643867.Ftrac_2924	0.0005008	51.0	292U1@1|root,2ZQBP@2|Bacteria,4NNH4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1282356_2	1123368.AUIS01000002_gene1535	1.969e-101	351.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,2NCHN@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WXD1_k127_1282356_0	1382306.JNIM01000001_gene665	2.096e-294	920.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WXD1_k127_1315069_16	1120966.AUBU01000008_gene2379	3.674e-12	69.0	28WBK@1|root,2ZIC0@2|Bacteria,4P7B5@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1315069_10	1336235.JAEG01000002_gene481	3.44e-56	212.0	COG1764@1|root,COG1764@2|Bacteria,1RHVR@1224|Proteobacteria,2VG83@28211|Alphaproteobacteria,4BNHI@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
WXD1_k127_1315069_2	452637.Oter_4049	1.977e-167	545.0	COG0661@1|root,COG0661@2|Bacteria,46UJV@74201|Verrucomicrobia,3K7NS@414999|Opitutae	414999|Opitutae	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
WXD1_k127_1315069_17	861299.J421_3542	6.601e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WXD1_k127_1315069_4	926550.CLDAP_34140	2.019e-107	377.0	COG2304@1|root,COG2304@2|Bacteria,2G7VX@200795|Chloroflexi	200795|Chloroflexi	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA
WXD1_k127_1315069_14	861299.J421_0442	7.886e-33	139.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_1315069_15	395019.Bmul_1315	2.207e-24	117.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2VVVU@28216|Betaproteobacteria,1K9RD@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
WXD1_k127_1315069_6	404589.Anae109_0044	5.661e-71	257.0	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,42RGR@68525|delta/epsilon subdivisions,2WNWC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Phosphate acetyl butaryl transferase	-	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
WXD1_k127_1315069_3	404589.Anae109_0045	6.257e-114	378.0	COG3426@1|root,COG3426@2|Bacteria,1PMSV@1224|Proteobacteria,42Q9P@68525|delta/epsilon subdivisions,2WKZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the acetokinase family	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
WXD1_k127_1315069_18	96561.Dole_0366	0.0009716	48.0	2E5WH@1|root,330KI@2|Bacteria	2|Bacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WXD1_k127_1315069_11	289376.THEYE_A0779	3.473e-43	171.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
WXD1_k127_1315069_8	1379858.N508_00488	2.796e-60	238.0	COG0493@1|root,COG0493@2|Bacteria,2GF1T@200930|Deferribacteres	200930|Deferribacteres	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
WXD1_k127_1315069_1	1121468.AUBR01000022_gene2795	3.398e-178	597.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,42EZ8@68295|Thermoanaerobacterales	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
WXD1_k127_1315069_0	234267.Acid_1536	1.222e-204	659.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3IB@57723|Acidobacteria	57723|Acidobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WXD1_k127_1315069_5	1254432.SCE1572_26550	3.07e-78	269.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WXD1_k127_1315069_7	1144275.COCOR_01809	1.448e-66	244.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2Z0T8@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
WXD1_k127_1315069_9	240292.Ava_2364	4.409e-58	211.0	COG0586@1|root,COG0586@2|Bacteria,1G39B@1117|Cyanobacteria,1HJ8Z@1161|Nostocales	1117|Cyanobacteria	S	PFAM SNARE associated Golgi protein	dedA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	SNARE_assoc
WXD1_k127_1315069_12	1122185.N792_08185	5.772e-40	154.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales	135614|Xanthomonadales	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WXD1_k127_1319687_12	379066.GAU_1670	4.699e-09	59.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
WXD1_k127_1319687_2	379066.GAU_1671	1.625e-121	406.0	COG2896@1|root,COG2896@2|Bacteria,1ZSMN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
WXD1_k127_1319687_8	530564.Psta_2344	3.014e-32	134.0	COG0314@1|root,COG0314@2|Bacteria,2IZSA@203682|Planctomycetes	203682|Planctomycetes	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
WXD1_k127_1319687_13	869210.Marky_0307	4.718e-09	67.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1WIMD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
WXD1_k127_1319687_14	2074.JNYD01000024_gene2834	1.227e-06	59.0	2BTY3@1|root,32P6C@2|Bacteria,2I8RQ@201174|Actinobacteria,4ECZJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WXD1_k127_1319687_10	1128421.JAGA01000001_gene2328	2.936e-25	113.0	COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_1319687_9	379066.GAU_1674	6.039e-31	125.0	COG0776@1|root,COG0776@2|Bacteria,1ZTTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WXD1_k127_1319687_7	338963.Pcar_1881	3.053e-42	160.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,43S2J@69541|Desulfuromonadales	28221|Deltaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
WXD1_k127_1319687_11	1121413.JMKT01000008_gene1568	1.532e-13	76.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,2M961@213115|Desulfovibrionales	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
WXD1_k127_1319687_1	861299.J421_3306	4.746e-130	425.0	COG0505@1|root,COG0505@2|Bacteria,1ZT0T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
WXD1_k127_1319687_5	861299.J421_2372	2.28e-61	218.0	COG0328@1|root,COG0328@2|Bacteria,1ZTI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
WXD1_k127_1319687_6	1123252.ATZF01000001_gene1384	6.808e-61	223.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,4HH4H@91061|Bacilli,27BP7@186824|Thermoactinomycetaceae	91061|Bacilli	H	Biotin/lipoate A/B protein ligase family	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WXD1_k127_1319687_4	1121920.AUAU01000004_gene789	3.917e-103	358.0	COG0508@1|root,COG0508@2|Bacteria,3Y3CV@57723|Acidobacteria	57723|Acidobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WXD1_k127_1319687_0	861299.J421_3597	5.408e-142	458.0	COG0022@1|root,COG0022@2|Bacteria,1ZT89@142182|Gemmatimonadetes	2|Bacteria	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K00167,ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WXD1_k127_1319687_3	861299.J421_3598	3.911e-114	378.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	2|Bacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	bfmBA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381,ko:K21416	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WXD1_k127_1325925_2	215803.DB30_7238	1.844e-187	591.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YXZJ@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WXD1_k127_1325925_12	573413.Spirs_1525	1.517e-35	151.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	cheW3	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WXD1_k127_1325925_5	326427.Cagg_0668	2.083e-60	240.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
WXD1_k127_1325925_8	1179773.BN6_18910	8.945e-44	164.0	COG5646@1|root,COG5646@2|Bacteria,2IMR2@201174|Actinobacteria,4E5VC@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WXD1_k127_1325925_16	411901.BACCAC_03337	1.879e-13	75.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,4NFEF@976|Bacteroidetes,2FNF0@200643|Bacteroidia,4AMI1@815|Bacteroidaceae	976|Bacteroidetes	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WXD1_k127_1325925_13	1449049.JONW01000011_gene2311	1.872e-29	123.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1325925_11	379066.GAU_2654	1.088e-35	151.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TPR_6
WXD1_k127_1325925_18	573061.Clocel_4109	0.000294	53.0	COG3210@1|root,COG3210@2|Bacteria,1UJPN@1239|Firmicutes,25FF8@186801|Clostridia,36V40@31979|Clostridiaceae	186801|Clostridia	U	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new
WXD1_k127_1325925_14	1219049.SP5_066_00040	4.25e-22	111.0	COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,2TVVR@28211|Alphaproteobacteria,2KE8N@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
WXD1_k127_1325925_7	861299.J421_6108	2.363e-47	187.0	COG2972@1|root,COG2972@2|Bacteria,1ZUX6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
WXD1_k127_1325925_6	861299.J421_6109	6.171e-57	220.0	COG3279@1|root,COG3279@2|Bacteria,1ZUZN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WXD1_k127_1325925_15	234267.Acid_5014	4.842e-21	106.0	COG0680@1|root,COG0680@2|Bacteria,3Y95V@57723|Acidobacteria	57723|Acidobacteria	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1325925_1	926569.ANT_12550	5.81e-195	624.0	COG3259@1|root,COG3259@2|Bacteria,2G68W@200795|Chloroflexi	200795|Chloroflexi	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WXD1_k127_1325925_4	234267.Acid_5016	1.864e-71	245.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	iJN678.hoxY	Oxidored_q6
WXD1_k127_1325925_3	234267.Acid_5017	6.807e-84	308.0	COG3383@1|root,COG3383@2|Bacteria,3Y2T6@57723|Acidobacteria	2|Bacteria	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	hoxU	-	1.17.1.10,1.6.5.3	ko:K05299,ko:K05588	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.hoxU	Fer2_4,Fer4,Fer4_10,Fer4_6,Fer4_7,Fer4_9,Molybdop_Fe4S4,NADH-G_4Fe-4S_3
WXD1_k127_1325925_0	1047013.AQSP01000091_gene642	4.171e-279	899.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	sfrB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.12.1.3,1.17.1.10,1.6.5.3	ko:K00335,ko:K15022,ko:K18331	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_2080	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
WXD1_k127_1325925_9	158190.SpiGrapes_0198	2.859e-39	152.0	COG1905@1|root,COG1905@2|Bacteria,2J8R3@203691|Spirochaetes	203691|Spirochaetes	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WXD1_k127_1325925_10	383372.Rcas_3776	8.27e-38	157.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WXD1_k127_1325925_17	448385.sce1953	2.311e-12	73.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WXD1_k127_1340556_1	1121930.AQXG01000001_gene1105	1.319e-146	494.0	COG1470@1|root,COG1629@1|root,COG1470@2|Bacteria,COG4771@2|Bacteria,4NFQD@976|Bacteroidetes,1IPUD@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_1340556_2	1128421.JAGA01000002_gene236	6.901e-144	463.0	COG0180@1|root,COG0180@2|Bacteria,2NNQX@2323|unclassified Bacteria	2|Bacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WXD1_k127_1340556_5	289376.THEYE_A1338	6.48e-24	112.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WXD1_k127_1340556_7	42256.RradSPS_1270	4.482e-12	76.0	COG2881@1|root,COG2881@2|Bacteria	2|Bacteria	M	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
WXD1_k127_1340556_3	379066.GAU_0646	2.953e-81	275.0	COG1403@1|root,COG1403@2|Bacteria,1ZTF1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
WXD1_k127_1340556_0	379066.GAU_0925	7.201e-255	807.0	COG1198@1|root,COG1198@2|Bacteria,1ZTE9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
WXD1_k127_1340556_4	861299.J421_4178	2.064e-80	278.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
WXD1_k127_1356493_12	234267.Acid_6164	9.418e-18	94.0	COG0823@1|root,COG2374@1|root,COG3170@1|root,COG3291@1|root,COG3391@1|root,COG3867@1|root,COG4257@1|root,COG4625@1|root,COG0823@2|Bacteria,COG2374@2|Bacteria,COG3170@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG3867@2|Bacteria,COG4257@2|Bacteria,COG4625@2|Bacteria,3Y354@57723|Acidobacteria	2|Bacteria	M	PKD domain containing protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	3.2.1.4	ko:K01179,ko:K07004,ko:K13277,ko:K20276,ko:K21449	ko00500,ko01100,ko02024,map00500,map01100,map02024	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	GH5,GH9	-	Big_3_2,Exo_endo_phos,He_PIG,LTD
WXD1_k127_1356493_10	1449076.JOOE01000002_gene742	4.355e-24	116.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,2JZX3@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	-	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WXD1_k127_1356493_5	880073.Calab_2437	5.014e-82	293.0	COG0265@1|root,COG0265@2|Bacteria,2NNVS@2323|unclassified Bacteria	2|Bacteria	O	smart pdz dhr glgf	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_1,PDZ_2,Trypsin_2
WXD1_k127_1356493_4	1379270.AUXF01000005_gene461	2.215e-86	323.0	COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
WXD1_k127_1356493_8	861299.J421_2906	7.289e-53	197.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WXD1_k127_1356493_11	1379270.AUXF01000005_gene460	3.777e-19	98.0	2FH8I@1|root,3492W@2|Bacteria,1ZTXF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1356493_6	861299.J421_2904	1.352e-71	264.0	COG1538@1|root,COG1538@2|Bacteria,1ZSMB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WXD1_k127_1356493_3	861299.J421_2903	4.41e-93	322.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
WXD1_k127_1356493_2	861299.J421_2902	1.069e-97	339.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_1356493_0	379066.GAU_1143	1.642e-105	356.0	COG0577@1|root,COG0577@2|Bacteria,1ZSU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WXD1_k127_1356493_1	1379270.AUXF01000005_gene455	1.083e-103	350.0	COG0577@1|root,COG0577@2|Bacteria,1ZUN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WXD1_k127_1356493_7	379066.GAU_1135	4.629e-65	243.0	COG2120@1|root,COG2120@2|Bacteria,1ZTDK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
WXD1_k127_1356493_13	379066.GAU_2951	6.183e-15	83.0	COG4206@1|root,COG4206@2|Bacteria,1ZU97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_1377270_1	886293.Sinac_0383	9.02e-131	430.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WXD1_k127_1377270_2	1123250.KB908393_gene230	5.707e-33	138.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,4H32B@909932|Negativicutes	909932|Negativicutes	H	Belongs to the precorrin methyltransferase family	cobA	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
WXD1_k127_1377270_0	861299.J421_3569	3.129e-168	540.0	COG0677@1|root,COG0677@2|Bacteria,1ZT42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WXD1_k127_1377270_4	1124780.ANNU01000063_gene591	6.793e-26	114.0	COG0250@1|root,COG0250@2|Bacteria,4NSVU@976|Bacteroidetes,47S81@768503|Cytophagia	976|Bacteroidetes	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
WXD1_k127_1377270_3	497964.CfE428DRAFT_2099	1.15e-27	117.0	COG0488@1|root,COG0488@2|Bacteria,46UUC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WXD1_k127_1384698_3	326424.FRAAL0410	2.693e-31	126.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WXD1_k127_1384698_1	656024.FsymDg_3491	3.807e-49	184.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4ETZ6@85013|Frankiales	201174|Actinobacteria	K	response regulator	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WXD1_k127_1384698_4	640510.BC1001_5565	1.217e-12	79.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VMG2@28216|Betaproteobacteria,1K0VE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
WXD1_k127_1384698_0	861299.J421_0160	2.85e-92	329.0	COG0840@1|root,COG0840@2|Bacteria,1ZUJ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
WXD1_k127_1384698_2	1121403.AUCV01000002_gene474	3.564e-43	162.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	hom	-	1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19	ko:K00003,ko:K00058,ko:K01754,ko:K04767	ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00017,M00018,M00020,M00570	R00220,R00996,R01513,R01773,R01775	RC00031,RC00087,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3
WXD1_k127_1415704_0	484770.UFO1_2838	3.082e-148	491.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4H4MY@909932|Negativicutes	909932|Negativicutes	C	Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WXD1_k127_1415704_2	743836.AYNA01000112_gene953	1.494e-49	194.0	2ECN6@1|root,336K2@2|Bacteria,1NVTD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1415704_1	251221.35211765	2.567e-101	351.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WXD1_k127_1416412_4	861299.J421_0158	1.872e-73	256.0	COG1352@1|root,COG1352@2|Bacteria,1ZSZM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WXD1_k127_1416412_3	861299.J421_0160	1.394e-89	321.0	COG0840@1|root,COG0840@2|Bacteria,1ZUJ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
WXD1_k127_1416412_6	379066.GAU_1785	2.467e-20	96.0	COG0810@1|root,COG0810@2|Bacteria,1ZU29@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WXD1_k127_1416412_0	861299.J421_0160	1.923e-102	360.0	COG0840@1|root,COG0840@2|Bacteria,1ZUJ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
WXD1_k127_1416412_1	861299.J421_0160	1.632e-100	357.0	COG0840@1|root,COG0840@2|Bacteria,1ZUJ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
WXD1_k127_1416412_2	379066.GAU_3239	2.038e-97	344.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1ZUEF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
WXD1_k127_1416412_5	237368.SCABRO_01102	8.161e-44	166.0	COG0835@1|root,COG0835@2|Bacteria,2J076@203682|Planctomycetes	203682|Planctomycetes	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WXD1_k127_1416412_7	1379270.AUXF01000002_gene1692	3.646e-20	93.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1ZTCI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
WXD1_k127_1421919_2	335543.Sfum_1265	1.406e-08	63.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2MQFN@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
WXD1_k127_1421919_1	1379270.AUXF01000005_gene655	4.827e-67	233.0	COG0634@1|root,COG0634@2|Bacteria,1ZTH7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WXD1_k127_1421919_0	861299.J421_3042	8.907e-232	728.0	COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
WXD1_k127_1430963_2	644282.Deba_0900	1.211e-60	220.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,42NE6@68525|delta/epsilon subdivisions,2WJ92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
WXD1_k127_1430963_0	861299.J421_3170	4.956e-79	282.0	COG1208@1|root,COG1208@2|Bacteria,1ZSVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Sugar nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_4
WXD1_k127_1430963_1	1379270.AUXF01000005_gene805	1.008e-69	246.0	COG0836@1|root,COG0836@2|Bacteria,1ZT5Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WXD1_k127_1458644_0	861299.J421_2499	1.278e-167	546.0	COG2204@1|root,COG2204@2|Bacteria,1ZSZ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_1464860_0	1379270.AUXF01000001_gene2296	2.283e-122	417.0	COG1196@1|root,COG1196@2|Bacteria,1ZU8V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1478736_0	861299.J421_6141	1.371e-148	501.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_6141|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1504544_0	397291.C804_02948	1.12e-159	518.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,27J6Z@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Helix-hairpin-helix motif	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WXD1_k127_1504544_5	1250232.JQNJ01000001_gene1261	0.0001008	54.0	COG0322@1|root,COG0322@2|Bacteria,4NGEV@976|Bacteroidetes,1HY6H@117743|Flavobacteriia	976|Bacteroidetes	L	Domain of unknown function (DUF4837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4837
WXD1_k127_1504544_3	472759.Nhal_3182	9.974e-44	170.0	COG0637@1|root,COG1554@1|root,COG1877@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,COG1877@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria,1X03I@135613|Chromatiales	135613|Chromatiales	G	Glycosyl hydrolase family 65 central catalytic domain	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Trehalose_PPase
WXD1_k127_1504544_1	861299.J421_1859	1.871e-80	291.0	COG0475@1|root,COG0475@2|Bacteria,1ZTBI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WXD1_k127_1504544_2	1489678.RDMS_12985	9.485e-76	271.0	COG1230@1|root,COG1230@2|Bacteria	2|Bacteria	P	cation diffusion facilitator family transporter	zitB	GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	iNRG857_1313.NRG857_03325,iPC815.YPO1129	Cation_efflux,ZT_dimer
WXD1_k127_1504544_4	883.DvMF_2505	1.433e-33	147.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TJK@68525|delta/epsilon subdivisions,2WQ0Z@28221|Deltaproteobacteria,2MBJY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WXD1_k127_1509169_7	518766.Rmar_1082	3.283e-44	171.0	COG4843@1|root,COG4843@2|Bacteria,4NRH5@976|Bacteroidetes	976|Bacteroidetes	S	UPF0316 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
WXD1_k127_1509169_2	1121918.ARWE01000001_gene3122	1.64e-121	403.0	COG1752@1|root,COG1752@2|Bacteria,1Q4S1@1224|Proteobacteria,42S86@68525|delta/epsilon subdivisions,2WNJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WXD1_k127_1509169_1	861299.J421_1663	1.243e-141	459.0	COG3191@1|root,COG3191@2|Bacteria,1ZT47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WXD1_k127_1509169_10	290397.Adeh_2529	5.469e-09	64.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_22,Fer4_8,FrhB_FdhB_C
WXD1_k127_1509169_8	404589.Anae109_1337	2.909e-23	113.0	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,42Q09@68525|delta/epsilon subdivisions,2WKE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
WXD1_k127_1509169_4	861299.J421_2407	1.158e-78	280.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1ZT3S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
WXD1_k127_1509169_0	1379270.AUXF01000002_gene1826	1.998e-234	739.0	COG0843@1|root,COG0843@2|Bacteria,1ZSMG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WXD1_k127_1509169_6	861299.J421_2409	7.606e-62	218.0	COG1845@1|root,COG1845@2|Bacteria,1ZT8Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
WXD1_k127_1509169_9	479434.Sthe_1585	5.343e-13	76.0	2EKS3@1|root,33EFV@2|Bacteria,2GBBM@200795|Chloroflexi,27YP9@189775|Thermomicrobia	189775|Thermomicrobia	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
WXD1_k127_1509169_5	1379270.AUXF01000002_gene1829	3.539e-73	256.0	COG3336@1|root,COG3336@2|Bacteria,1ZT56@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
WXD1_k127_1509169_3	1297742.A176_01806	3.707e-99	334.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1518486_0	379066.GAU_0047	1.173e-49	186.0	COG2755@1|root,COG2755@2|Bacteria,1ZUS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WXD1_k127_1518486_1	861299.J421_1517	5.106e-42	170.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1527692_2	1379270.AUXF01000003_gene3895	2.69e-142	467.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WXD1_k127_1527692_3	1283299.AUKG01000005_gene42	3.738e-46	180.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CQ75@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WXD1_k127_1527692_4	880073.Calab_0057	1.748e-26	121.0	COG4105@1|root,COG4105@2|Bacteria,2NQ7U@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	yfiO	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
WXD1_k127_1527692_5	1184267.A11Q_2364	1.047e-20	102.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2MT2I@213481|Bdellovibrionales,2WQUR@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
WXD1_k127_1527692_0	861299.J421_0144	3.311e-177	567.0	COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes	2|Bacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WXD1_k127_1527692_1	861299.J421_0145	6.122e-143	485.0	COG0451@1|root,COG0451@2|Bacteria,1ZUJJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WXD1_k127_1528773_1	379066.GAU_0050	5.096e-121	415.0	2C9ZY@1|root,33R5C@2|Bacteria,1ZSVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1528773_9	525373.HMPREF0766_14384	8.189e-30	133.0	COG1409@1|root,COG4775@1|root,COG1409@2|Bacteria,COG4775@2|Bacteria,4NF9N@976|Bacteroidetes,1IPKR@117747|Sphingobacteriia	976|Bacteroidetes	M	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Metallophos
WXD1_k127_1528773_0	472759.Nhal_2616	5.349e-148	490.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1WW9T@135613|Chromatiales	135613|Chromatiales	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
WXD1_k127_1528773_7	1123073.KB899242_gene1457	5.391e-53	194.0	COG0500@1|root,COG0500@2|Bacteria,1R947@1224|Proteobacteria,1SUF1@1236|Gammaproteobacteria,1X4RG@135614|Xanthomonadales	135614|Xanthomonadales	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25
WXD1_k127_1528773_3	1173026.Glo7428_4597	2.518e-112	381.0	COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria	1117|Cyanobacteria	P	Sodium calcium exchanger	ecm27	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
WXD1_k127_1528773_4	1279009.ADICEAN_03373	9.913e-103	362.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,47JF7@768503|Cytophagia	976|Bacteroidetes	E	PFAM amino acid permease-associated region	yeeF	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
WXD1_k127_1528773_5	1249480.B649_09535	2.864e-92	328.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42NGM@68525|delta/epsilon subdivisions,2YN51@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	receptor	-	-	-	ko:K02014,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10	-	-	Plug,TonB_dep_Rec
WXD1_k127_1528773_2	1210884.HG799463_gene9317	2.019e-117	411.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_1528773_8	269796.Rru_A0934	3.688e-32	136.0	COG1442@1|root,COG1442@2|Bacteria,1N02S@1224|Proteobacteria,2U241@28211|Alphaproteobacteria,2JU8S@204441|Rhodospirillales	204441|Rhodospirillales	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1528773_6	498848.TaqDRAFT_3469	1.54e-65	230.0	COG1089@1|root,COG1089@2|Bacteria,1WJ99@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WXD1_k127_1529467_2	1276756.AUEX01000006_gene3096	1.827e-64	222.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,4ADHM@80864|Comamonadaceae	28216|Betaproteobacteria	F	phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
WXD1_k127_1529467_0	595537.Varpa_5218	9.314e-188	590.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,4ABIN@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WXD1_k127_1529467_1	365046.Rta_34070	1.36e-72	248.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,4AA5D@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM amidohydrolase	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WXD1_k127_1548427_0	1206729.BAFZ01000061_gene3654	1.248e-109	372.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4FYUZ@85025|Nocardiaceae	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WXD1_k127_1548427_1	1379270.AUXF01000006_gene315	4.821e-77	269.0	COG1159@1|root,COG1159@2|Bacteria,1ZUSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WXD1_k127_1548427_2	861299.J421_3206	1.503e-21	94.0	COG2835@1|root,COG2835@2|Bacteria,1ZU7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
WXD1_k127_1553753_4	1379270.AUXF01000005_gene723	1.388e-77	270.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1ZSNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
WXD1_k127_1553753_8	1089551.KE386572_gene2195	6.684e-42	173.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria,4BQD9@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
WXD1_k127_1553753_0	861299.J421_3116	1.905e-172	552.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1ZT7J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
WXD1_k127_1553753_6	1480694.DC28_11320	6.948e-47	175.0	COG0054@1|root,COG0054@2|Bacteria,2J7D1@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
WXD1_k127_1553753_10	1123371.ATXH01000011_gene65	4.98e-26	112.0	COG0781@1|root,COG0781@2|Bacteria,2GHUU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WXD1_k127_1553753_2	861299.J421_3119	1.489e-119	401.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_1553753_14	879305.HMPREF9290_0632	1.102e-05	51.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,22GYX@1570339|Peptoniphilaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
WXD1_k127_1553753_3	379066.GAU_1477	8.4e-112	375.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
WXD1_k127_1553753_13	749927.AMED_1370	9.63e-07	57.0	COG2893@1|root,COG2893@2|Bacteria,2GWNE@201174|Actinobacteria,4EDH5@85010|Pseudonocardiales	201174|Actinobacteria	G	PTS system fructose IIA component	-	-	2.7.1.191	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
WXD1_k127_1553753_9	379066.GAU_1479	9.19e-40	153.0	COG3444@1|root,COG3444@2|Bacteria,1ZTQR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system sorbose subfamily IIB component	-	-	-	ko:K19507	ko02060,map02060	M00764	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.19	-	-	PTSIIB_sorb
WXD1_k127_1553753_12	1232410.KI421421_gene3596	9.197e-10	70.0	COG3715@1|root,COG3715@2|Bacteria,1RHFJ@1224|Proteobacteria,42SZF@68525|delta/epsilon subdivisions,2WPSS@28221|Deltaproteobacteria,43SK0@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
WXD1_k127_1553753_7	379066.GAU_1481	1.257e-43	177.0	COG3716@1|root,COG3716@2|Bacteria,1ZTJH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system mannose/fructose/sorbose family IID component	-	-	-	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EIID-AGA
WXD1_k127_1553753_11	1379270.AUXF01000005_gene735	1.72e-23	113.0	COG1925@1|root,COG1925@2|Bacteria,1ZTYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
WXD1_k127_1553753_1	273068.TTE2334	4.449e-133	445.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
WXD1_k127_1553753_5	861299.J421_3129	6.058e-47	176.0	COG1259@1|root,COG1259@2|Bacteria,1ZTKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
WXD1_k127_1618111_4	379066.GAU_1206	7.866e-25	109.0	COG0360@1|root,COG0360@2|Bacteria,1ZTYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WXD1_k127_1618111_2	1210884.HG799463_gene9317	9.363e-109	384.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_1618111_1	1379270.AUXF01000005_gene517	1.185e-137	449.0	COG0012@1|root,COG0012@2|Bacteria,1ZSPQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WXD1_k127_1618111_3	1122611.KB903943_gene1520	2.256e-51	190.0	COG2186@1|root,COG2186@2|Bacteria,2IB40@201174|Actinobacteria,4EM5I@85012|Streptosporangiales	201174|Actinobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
WXD1_k127_1624132_5	861299.J421_2380	1.561e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,1ZSWF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_1624132_2	1265313.HRUBRA_00218	8.902e-164	533.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,1RQAM@1236|Gammaproteobacteria,1J4HJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WXD1_k127_1624132_3	68570.DC74_490	1.423e-92	310.0	COG3340@1|root,COG3340@2|Bacteria,2GN35@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the peptidase S51 family	pepE	GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WXD1_k127_1624132_1	1123508.JH636447_gene7779	5.72e-190	601.0	COG1063@1|root,COG1063@2|Bacteria,2IXCG@203682|Planctomycetes	203682|Planctomycetes	C	COG1063 Threonine dehydrogenase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
WXD1_k127_1624132_6	1121127.JAFA01000009_gene7032	1.681e-18	96.0	COG3652@1|root,COG3652@2|Bacteria,1RDPI@1224|Proteobacteria,2VRQA@28216|Betaproteobacteria,1K202@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4142)	-	-	-	ko:K08995	-	-	-	-	ko00000	-	-	-	DUF4142
WXD1_k127_1624132_0	1379270.AUXF01000005_gene764	1.43e-202	654.0	COG2366@1|root,COG2366@2|Bacteria,1ZUMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Penicillin amidase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
WXD1_k127_1624132_4	1123248.KB893327_gene788	1.765e-60	212.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WXD1_k127_1659783_3	638303.Thal_0247	8.012e-78	269.0	COG0351@1|root,COG0351@2|Bacteria	2|Bacteria	H	phosphomethylpyrimidine kinase activity	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00941,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI
WXD1_k127_1659783_2	861299.J421_3637	3.993e-81	293.0	COG0747@1|root,COG0747@2|Bacteria,1ZTAS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WXD1_k127_1659783_4	1341151.ASZU01000003_gene2690	1.196e-75	284.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,27BBV@186824|Thermoactinomycetaceae	91061|Bacilli	F	Phosphorylase superfamily	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WXD1_k127_1659783_0	756067.MicvaDRAFT_2384	3.758e-128	428.0	COG1972@1|root,COG1972@2|Bacteria,1G3CA@1117|Cyanobacteria,1H7FT@1150|Oscillatoriales	1117|Cyanobacteria	F	PFAM Na dependent nucleoside transporter	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
WXD1_k127_1659783_5	246197.MXAN_0661	1.884e-70	250.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WXD1_k127_1659783_1	1051632.TPY_1182	3.634e-103	343.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WCEV@538999|Clostridiales incertae sedis	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WXD1_k127_1677093_4	404589.Anae109_0100	9.912e-111	371.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales	28221|Deltaproteobacteria	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
WXD1_k127_1677093_2	1379270.AUXF01000003_gene3570	7.948e-214	724.0	COG0737@1|root,COG0737@2|Bacteria,1ZTEA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
WXD1_k127_1677093_0	861299.J421_3382	0.0	1122.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1ZU89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WXD1_k127_1677093_3	861299.J421_3381	1.415e-158	512.0	COG0034@1|root,COG0034@2|Bacteria,1ZTD7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6
WXD1_k127_1677093_1	861299.J421_3380	3.649e-316	985.0	COG0046@1|root,COG0046@2|Bacteria,1ZT8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WXD1_k127_1677093_5	379066.GAU_1736	7.182e-28	114.0	COG0047@1|root,COG0047@2|Bacteria,1ZTF8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WXD1_k127_168155_0	861299.J421_2707	1.258e-137	455.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
WXD1_k127_1706824_1	379066.GAU_2996	1.168e-50	190.0	COG0656@1|root,COG0656@2|Bacteria,1ZURF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WXD1_k127_1706824_0	56780.SYN_03643	4.918e-235	733.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2MQTC@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
WXD1_k127_1707379_7	1121930.AQXG01000004_gene2850	9.518e-33	129.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1IW1A@117747|Sphingobacteriia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
WXD1_k127_1707379_5	1356852.N008_19240	1.51e-43	171.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,47QUH@768503|Cytophagia	976|Bacteroidetes	S	PFAM phospholipase Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
WXD1_k127_1707379_6	861299.J421_0649	1.608e-43	171.0	COG0596@1|root,COG0596@2|Bacteria	861299.J421_0649|-	S	hydrolase activity, acting on ester bonds	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	-
WXD1_k127_1707379_1	861299.J421_3515	1.657e-137	448.0	COG0579@1|root,COG0579@2|Bacteria	2|Bacteria	S	malate dehydrogenase (menaquinone) activity	lhgO	-	1.1.99.2	ko:K00109,ko:K15736	ko00650,map00650	-	R03534	RC00031	ko00000,ko00001,ko01000	-	-	-	DAO
WXD1_k127_1707379_0	861299.J421_2166	4.479e-312	974.0	COG1529@1|root,COG1529@2|Bacteria,1ZSUN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
WXD1_k127_1707379_4	861299.J421_2167	2.594e-74	253.0	COG2080@1|root,COG2080@2|Bacteria,1ZTHW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WXD1_k127_1707379_3	69395.JQLZ01000002_gene1516	3.951e-85	301.0	COG2367@1|root,COG2367@2|Bacteria,1NMW4@1224|Proteobacteria,2TX7R@28211|Alphaproteobacteria,2KGVQ@204458|Caulobacterales	204458|Caulobacterales	V	beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
WXD1_k127_1707379_2	1123253.AUBD01000010_gene2177	2.464e-132	440.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria,1X4FD@135614|Xanthomonadales	135614|Xanthomonadales	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WXD1_k127_1725453_4	1101189.AQUO01000001_gene2453	0.0003855	43.0	COG5457@1|root,COG5457@2|Bacteria,1NHHX@1224|Proteobacteria,2UJ9Y@28211|Alphaproteobacteria,2PXW9@265|Paracoccus	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1127
WXD1_k127_1725453_3	391593.RCCS2_05614	1.493e-11	72.0	2EACX@1|root,334GT@2|Bacteria,1N8Z0@1224|Proteobacteria,2UFXD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1725453_1	861299.J421_6332	3.379e-118	393.0	COG1680@1|root,COG1680@2|Bacteria,1ZTCC@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
WXD1_k127_1725453_0	365046.Rta_06880	1.533e-152	489.0	COG1793@1|root,COG1793@2|Bacteria,1R4SI@1224|Proteobacteria,2W01H@28216|Betaproteobacteria,4AGE3@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
WXD1_k127_1725453_2	365046.Rta_06820	1.066e-80	274.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria,4ABMF@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
WXD1_k127_1729743_2	379066.GAU_0579	7.878e-74	267.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1ZSP0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	DM	Chain length determinant protein	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	GNVR
WXD1_k127_1729743_0	1379270.AUXF01000004_gene3319	1.489e-180	581.0	COG2204@1|root,COG2204@2|Bacteria,1ZSZ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_1729743_3	861299.J421_2500	1.985e-57	214.0	COG0642@1|root,COG0642@2|Bacteria,1ZTZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WXD1_k127_1729743_1	861299.J421_2477	1.363e-96	330.0	COG1269@1|root,COG1269@2|Bacteria,1ZT23@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
WXD1_k127_1729743_4	861299.J421_2478	2.435e-55	202.0	COG1269@1|root,COG1269@2|Bacteria,1ZTKR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
WXD1_k127_1729743_5	886293.Sinac_0881	3.913e-28	132.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2IYJM@203682|Planctomycetes	203682|Planctomycetes	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,PAS_4
WXD1_k127_1729743_10	926566.Terro_4017	3.019e-05	58.0	COG1629@1|root,COG4771@2|Bacteria,3Y9D4@57723|Acidobacteria,2JP0W@204432|Acidobacteriia	204432|Acidobacteriia	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WXD1_k127_1729743_8	1267533.KB906736_gene887	9.265e-08	66.0	COG1629@1|root,COG4771@2|Bacteria,3Y99N@57723|Acidobacteria,2JM3Y@204432|Acidobacteriia	204432|Acidobacteriia	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
WXD1_k127_1729743_9	525904.Tter_0496	1.34e-05	59.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_1,Exo_endo_phos,LTD
WXD1_k127_1729743_7	272943.RSP_6136	7.139e-08	66.0	COG2273@1|root,COG2273@2|Bacteria,1N51G@1224|Proteobacteria,2UDP4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
WXD1_k127_1729743_6	351607.Acel_0620	2.317e-26	123.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,2IHK9@201174|Actinobacteria,4EU1T@85013|Frankiales	201174|Actinobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WXD1_k127_1729743_11	224911.27350827	4.567e-05	47.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1729743_12	1158294.JOMI01000009_gene919	0.000308	49.0	2DR8D@1|root,33ANQ@2|Bacteria,4NYGG@976|Bacteroidetes,2FVPJ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1732781_1	861299.J421_5728	4.611e-125	430.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
WXD1_k127_1732781_3	562970.Btus_1874	3.95e-17	91.0	COG1011@1|root,COG1011@2|Bacteria,1UM5R@1239|Firmicutes,4ITQN@91061|Bacilli,278D3@186823|Alicyclobacillaceae	91061|Bacilli	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WXD1_k127_1732781_2	861299.J421_3990	8.52e-36	144.0	COG1186@1|root,COG1186@2|Bacteria,1ZTZD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
WXD1_k127_1732781_0	391625.PPSIR1_40115	4.039e-246	778.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,42NBE@68525|delta/epsilon subdivisions,2WMG2@28221|Deltaproteobacteria,2YUJX@29|Myxococcales	28221|Deltaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WXD1_k127_1732912_9	861299.J421_2015	7.168e-39	149.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WXD1_k127_1732912_6	861299.J421_2016	8.708e-88	304.0	COG0845@1|root,COG0845@2|Bacteria,1ZSR2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WXD1_k127_1732912_0	1278073.MYSTI_00516	0.0	1334.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX1A@29|Myxococcales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
WXD1_k127_1732912_8	861299.J421_3991	1.933e-48	183.0	29F5I@1|root,30238@2|Bacteria,1ZU4C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1732912_1	861299.J421_1224	6.459e-198	640.0	COG1629@1|root,COG4771@2|Bacteria,1ZUFR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug
WXD1_k127_1732912_2	215803.DB30_3561	3.489e-157	507.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WXD1_k127_1732912_3	215803.DB30_3562	5.18e-126	432.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42U6K@68525|delta/epsilon subdivisions,2WQ4K@28221|Deltaproteobacteria,2YZCG@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
WXD1_k127_1732912_5	204669.Acid345_3324	5.439e-96	333.0	COG1136@1|root,COG1136@2|Bacteria,3Y30Q@57723|Acidobacteria,2JI7R@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_1732912_4	1278073.MYSTI_03753	3.465e-109	376.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WXD1_k127_1732912_12	794903.OPIT5_00805	1.156e-07	61.0	2A1I4@1|root,30PRV@2|Bacteria,46XXK@74201|Verrucomicrobia,3K8JP@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1732912_11	1444309.JAQG01000147_gene997	6.363e-16	88.0	COG1595@1|root,COG1595@2|Bacteria,1V7NX@1239|Firmicutes,4HJXE@91061|Bacilli,26XIN@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_1732912_7	742738.HMPREF9460_02924	3.573e-53	203.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,268XC@186813|unclassified Clostridiales	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WXD1_k127_1732912_10	215803.DB30_7286	1.056e-23	106.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria,2YXIY@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
WXD1_k127_1736586_2	379066.GAU_2851	1.405e-85	292.0	COG1162@1|root,COG1162@2|Bacteria,1ZSSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
WXD1_k127_1736586_0	379066.GAU_0710	4.849e-104	355.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WXD1_k127_1736586_5	709986.Deima_3287	4.055e-49	185.0	COG0631@1|root,COG0631@2|Bacteria,1WIBX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
WXD1_k127_1736586_1	379066.GAU_0292	8.239e-101	334.0	COG1131@1|root,COG1131@2|Bacteria,1ZT45@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_1736586_4	861299.J421_0236	4.048e-62	241.0	29YN3@1|root,30KHK@2|Bacteria,1ZT0C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
WXD1_k127_1736586_3	234267.Acid_6592	6.997e-64	234.0	COG0153@1|root,COG0153@2|Bacteria,3Y300@57723|Acidobacteria	2|Bacteria	G	Belongs to the GHMP kinase family. GalK subfamily	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WXD1_k127_1742477_0	1996.JOFO01000057_gene826	2.503e-153	486.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4EFUP@85012|Streptosporangiales	201174|Actinobacteria	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WXD1_k127_1742477_1	1192034.CAP_1547	1.38e-148	488.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria,2YUQE@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439,ko:K13049	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WXD1_k127_1742477_3	469383.Cwoe_1506	4.474e-30	136.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
WXD1_k127_1742477_2	714943.Mucpa_0545	8.226e-63	230.0	COG2855@1|root,COG2855@2|Bacteria,4NES6@976|Bacteroidetes,1IP6B@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
WXD1_k127_1743818_1	426355.Mrad2831_2427	3.875e-98	343.0	COG0491@1|root,COG0491@2|Bacteria,1Q861@1224|Proteobacteria,2U29C@28211|Alphaproteobacteria,1JT0M@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WXD1_k127_1743818_2	861299.J421_3913	1.557e-60	222.0	COG1912@1|root,COG1912@2|Bacteria,1ZTIH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
WXD1_k127_1743818_0	1379270.AUXF01000003_gene3479	2.926e-104	350.0	COG0489@1|root,COG0489@2|Bacteria,1ZSW7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
WXD1_k127_1743818_3	1157490.EL26_01350	8.028e-22	96.0	COG0694@1|root,COG0694@2|Bacteria,1VAAU@1239|Firmicutes,4HKQ8@91061|Bacilli,278KT@186823|Alicyclobacillaceae	91061|Bacilli	O	NifU-like domain	yutI	-	-	-	-	-	-	-	-	-	-	-	NifU
WXD1_k127_1766380_3	861299.J421_3093	1.205e-74	267.0	COG0787@1|root,COG0787@2|Bacteria,1ZT57@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WXD1_k127_1766380_5	861299.J421_3092	3.971e-68	240.0	COG1694@1|root,COG3956@2|Bacteria,1ZSZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
WXD1_k127_1766380_0	861299.J421_3089	2.152e-193	612.0	COG0017@1|root,COG0017@2|Bacteria,1ZSTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WXD1_k127_1766380_8	1121033.AUCF01000001_gene2332	3.506e-09	68.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,2JP9X@204441|Rhodospirillales	204441|Rhodospirillales	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
WXD1_k127_1766380_4	765420.OSCT_1231	5.697e-71	258.0	COG3437@1|root,COG3437@2|Bacteria,2G6QF@200795|Chloroflexi,37587@32061|Chloroflexia	200795|Chloroflexi	KT	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
WXD1_k127_1766380_6	1379270.AUXF01000005_gene699	3.841e-66	231.0	COG1200@1|root,COG1200@2|Bacteria,1ZT3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WXD1_k127_1766380_1	1379698.RBG1_1C00001G0402	6.171e-122	408.0	COG1200@1|root,COG1200@2|Bacteria,2NNS3@2323|unclassified Bacteria	2|Bacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WXD1_k127_1766380_2	861299.J421_3083	5.847e-108	358.0	COG0552@1|root,COG0552@2|Bacteria,1ZTBT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WXD1_k127_1766380_7	861299.J421_3082	2.832e-47	192.0	COG1572@1|root,COG1572@2|Bacteria,1ZSTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1774285_4	1121377.KB906404_gene2820	7.465e-07	57.0	COG2333@1|root,COG2333@2|Bacteria	2|Bacteria	N	competence protein COMEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Excalibur,Lactamase_B
WXD1_k127_1774285_3	379066.GAU_1269	8.366e-31	124.0	COG0640@1|root,COG0640@2|Bacteria,1ZV07@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WXD1_k127_1774285_1	452637.Oter_4062	1.817e-125	411.0	COG0701@1|root,COG0701@2|Bacteria,46VTG@74201|Verrucomicrobia,3K8S1@414999|Opitutae	414999|Opitutae	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WXD1_k127_1774285_2	1379270.AUXF01000001_gene2711	2.256e-114	374.0	COG0639@1|root,COG0639@2|Bacteria,1ZUFY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WXD1_k127_1774285_0	857087.Metme_4156	1.587e-166	530.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,1XF21@135618|Methylococcales	135618|Methylococcales	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WXD1_k127_1774859_0	861299.J421_1193	3.454e-236	737.0	28HPB@1|root,2Z7XC@2|Bacteria	2|Bacteria	S	PFAM Heparinase II III family protein	alyll	-	4.2.2.26	ko:K20525	-	-	-	-	ko00000,ko01000	-	-	-	Alginate_lyase,Hepar_II_III
WXD1_k127_1774859_4	861299.J421_1194	1.09e-76	276.0	COG1028@1|root,COG1028@2|Bacteria	861299.J421_1194|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
WXD1_k127_1774859_1	861299.J421_1196	1.094e-191	608.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	exuT	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
WXD1_k127_1774859_7	518766.Rmar_1763	8.642e-24	109.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,1FK7R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
WXD1_k127_1774859_5	1127692.HMPREF9075_01962	4.865e-60	216.0	COG0388@1|root,COG0388@2|Bacteria,4NE37@976|Bacteroidetes,1HXV8@117743|Flavobacteriia	976|Bacteroidetes	S	amidohydrolase	yafV	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WXD1_k127_1774859_3	1089550.ATTH01000001_gene719	7.525e-111	371.0	COG1946@1|root,COG1946@2|Bacteria,4NEY8@976|Bacteroidetes,1FJYZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Thioesterase-like superfamily	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
WXD1_k127_1774859_2	1125863.JAFN01000001_gene1528	2.674e-119	398.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_1774859_8	1307761.L21SP2_2216	9.805e-21	97.0	COG1725@1|root,COG1725@2|Bacteria,2J9B8@203691|Spirochaetes	203691|Spirochaetes	K	transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
WXD1_k127_1774859_6	635013.TherJR_2700	1.102e-47	183.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,2613U@186807|Peptococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_1777690_1	404380.Gbem_1695	1.242e-47	194.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42S6I@68525|delta/epsilon subdivisions,2WNNW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TOBE domain	-	-	3.6.3.29,3.6.3.55	ko:K02017,ko:K06857	ko02010,map02010	M00186,M00189	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4,3.A.1.8	-	-	ABC_tran,TOBE
WXD1_k127_1777690_0	1121920.AUAU01000011_gene228	7.189e-68	237.0	COG4662@1|root,COG4662@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
WXD1_k127_1777690_2	1121920.AUAU01000011_gene226	2.958e-31	126.0	COG2998@1|root,COG2998@2|Bacteria	2|Bacteria	H	PBP superfamily domain	tupB	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WXD1_k127_1796058_0	1379270.AUXF01000001_gene2542	9.647e-220	705.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WXD1_k127_1796058_6	1239962.C943_00699	5.061e-44	166.0	COG2370@1|root,COG2370@2|Bacteria,4NMRP@976|Bacteroidetes,47MSF@768503|Cytophagia	976|Bacteroidetes	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
WXD1_k127_1796058_3	702113.PP1Y_AT3268	2.875e-73	260.0	COG5654@1|root,COG5654@2|Bacteria,1N5WH@1224|Proteobacteria,2U4CY@28211|Alphaproteobacteria,2K0WX@204457|Sphingomonadales	204457|Sphingomonadales	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
WXD1_k127_1796058_5	631454.N177_1121	2.19e-46	171.0	COG5642@1|root,COG5642@2|Bacteria,1N1FN@1224|Proteobacteria,2VBHR@28211|Alphaproteobacteria,1JQKX@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
WXD1_k127_1796058_1	886293.Sinac_4664	9.306e-120	399.0	COG1819@1|root,COG1819@2|Bacteria,2IZT0@203682|Planctomycetes	203682|Planctomycetes	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
WXD1_k127_1796058_4	861299.J421_4499	1.148e-49	188.0	2A1J8@1|root,3312R@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1906)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1906
WXD1_k127_1796058_2	378806.STAUR_0942	1.657e-101	339.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,4383U@68525|delta/epsilon subdivisions,2X3DT@28221|Deltaproteobacteria,2YVM7@29|Myxococcales	28221|Deltaproteobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WXD1_k127_1796058_7	709986.Deima_2910	1.353e-35	142.0	COG3118@1|root,COG3118@2|Bacteria,1WK9V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WXD1_k127_1797814_7	1379270.AUXF01000006_gene62	5.044e-125	411.0	COG0484@1|root,COG0484@2|Bacteria,1ZSVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WXD1_k127_1797814_10	1379270.AUXF01000006_gene61	1.292e-105	353.0	COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
WXD1_k127_1797814_13	861299.J421_3470	4.641e-96	343.0	COG0635@1|root,COG0635@2|Bacteria,1ZSSU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WXD1_k127_1797814_19	1121430.JMLG01000026_gene27	5.565e-59	220.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,260T7@186807|Peptococcaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
WXD1_k127_1797814_6	861299.J421_3472	9.487e-127	413.0	COG0536@1|root,COG0536@2|Bacteria,1ZSVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
WXD1_k127_1797814_24	861299.J421_3473	6.291e-42	162.0	COG0599@1|root,COG0599@2|Bacteria,1ZTPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxymuconolactone decarboxylase family	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
WXD1_k127_1797814_15	215803.DB30_4629	2.469e-83	287.0	COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,42RKM@68525|delta/epsilon subdivisions,2WNVJ@28221|Deltaproteobacteria,2YX74@29|Myxococcales	28221|Deltaproteobacteria	E	L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
WXD1_k127_1797814_16	379066.GAU_1905	1.914e-71	263.0	COG0697@1|root,COG0697@2|Bacteria,1ZUKF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WXD1_k127_1797814_32	192952.MM_2849	5.323e-21	104.0	COG0730@1|root,arCOG02050@2157|Archaea,2XXQV@28890|Euryarchaeota,2NA68@224756|Methanomicrobia	224756|Methanomicrobia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WXD1_k127_1797814_9	861299.J421_2940	8.547e-117	396.0	COG0793@1|root,COG0793@2|Bacteria,1ZSUF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,Peptidase_S41
WXD1_k127_1797814_22	69042.WH5701_00755	1.108e-48	182.0	COG0125@1|root,COG0125@2|Bacteria,1G52G@1117|Cyanobacteria,1GZW5@1129|Synechococcus	1117|Cyanobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WXD1_k127_1797814_0	861299.J421_3601	2.282e-212	672.0	COG1260@1|root,COG1260@2|Bacteria,1ZT2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
WXD1_k127_1797814_27	379066.GAU_1998	4.805e-37	153.0	COG0558@1|root,COG0558@2|Bacteria,1ZTIP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WXD1_k127_1797814_30	379066.GAU_1186	9.378e-22	100.0	COG3679@1|root,COG3679@2|Bacteria,1ZTRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
WXD1_k127_1797814_20	861299.J421_2937	4.081e-55	203.0	COG2890@1|root,COG2890@2|Bacteria,1ZTQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Methyltransferase small domain	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
WXD1_k127_1797814_8	697281.Mahau_0242	1.206e-118	391.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,42FEW@68295|Thermoanaerobacterales	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WXD1_k127_1797814_29	243231.GSU3107	4.206e-26	109.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,43VM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WXD1_k127_1797814_17	1519464.HY22_08490	5.062e-71	263.0	COG0673@1|root,COG0673@2|Bacteria,1FEXT@1090|Chlorobi	1090|Chlorobi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WXD1_k127_1797814_18	861299.J421_2928	2.126e-59	224.0	COG2385@1|root,COG2385@2|Bacteria,1ZT25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
WXD1_k127_1797814_3	479434.Sthe_1801	1.79e-164	527.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi,27Y34@189775|Thermomicrobia	189775|Thermomicrobia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WXD1_k127_1797814_5	379066.GAU_1174	1.029e-130	438.0	COG0621@1|root,COG0621@2|Bacteria,1ZT70@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
WXD1_k127_1797814_31	861299.J421_2941	2.202e-21	107.0	COG2834@1|root,COG2834@2|Bacteria,1ZTXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
WXD1_k127_1797814_1	1379270.AUXF01000006_gene38	3.849e-208	670.0	COG1674@1|root,COG1674@2|Bacteria,1ZSPI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WXD1_k127_1797814_25	1379698.RBG1_1C00001G0649	8.931e-40	162.0	COG2045@1|root,COG2045@2|Bacteria,2NPF1@2323|unclassified Bacteria	2|Bacteria	H	Belongs to the ComB family	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
WXD1_k127_1797814_2	861299.J421_3533	4.217e-205	648.0	COG0439@1|root,COG0439@2|Bacteria,1ZT0Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WXD1_k127_1797814_26	861299.J421_3534	1.747e-37	154.0	COG0511@1|root,COG0511@2|Bacteria,1ZTR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
WXD1_k127_1797814_23	1125863.JAFN01000001_gene2274	2.107e-43	173.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
WXD1_k127_1797814_36	1211115.ALIQ01000193_gene10	2.098e-06	61.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2TSI7@28211|Alphaproteobacteria,3N9UQ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	O	Cytochrome c-type biogenesis protein	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19
WXD1_k127_1797814_14	861299.J421_3538	4.756e-89	317.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
WXD1_k127_1797814_34	518766.Rmar_2500	9.346e-12	68.0	COG1826@1|root,COG1826@2|Bacteria,4PETH@976|Bacteroidetes,1FJKH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WXD1_k127_1797814_35	379066.GAU_1931	1.171e-09	63.0	2FH8C@1|root,3492Q@2|Bacteria,1ZTXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
WXD1_k127_1797814_11	379066.GAU_1932	2.86e-104	351.0	COG0142@1|root,COG0142@2|Bacteria,1ZT7D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
WXD1_k127_1797814_21	861299.J421_3542	1.268e-54	214.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WXD1_k127_1797814_12	1235279.C772_00075	6.405e-98	354.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,4HAVY@91061|Bacilli,26DT5@186818|Planococcaceae	91061|Bacilli	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WXD1_k127_1797814_4	861299.J421_3546	3.527e-153	505.0	COG2986@1|root,COG2986@2|Bacteria,1ZTEG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WXD1_k127_1797814_28	861299.J421_1842	1.387e-27	130.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	litR	-	2.3.3.1	ko:K01647,ko:K22491	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WXD1_k127_1803101_2	1449080.JQMV01000003_gene1225	3.047e-39	159.0	COG1293@1|root,COG1293@2|Bacteria,1WJ78@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	RNA-binding protein homologous to eukaryotic snRNP	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
WXD1_k127_1803101_1	671143.DAMO_1413	1.452e-59	216.0	COG0159@1|root,COG0159@2|Bacteria,2NP9W@2323|unclassified Bacteria	2|Bacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
WXD1_k127_1803101_0	1379270.AUXF01000006_gene169	4.658e-124	415.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
WXD1_k127_1819032_0	379066.GAU_2797	6.836e-263	822.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WXD1_k127_1819032_1	234267.Acid_5053	1.166e-70	254.0	COG0520@1|root,COG0520@2|Bacteria,3Y4TH@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_1819032_2	391625.PPSIR1_07832	7.421e-54	206.0	COG1073@1|root,COG1073@2|Bacteria,1R4QH@1224|Proteobacteria,43C0C@68525|delta/epsilon subdivisions,2WKKS@28221|Deltaproteobacteria,2Z3EV@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1819032_3	644282.Deba_1367	3.326e-37	156.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
WXD1_k127_1828924_0	459349.CLOAM0355	7.915e-24	111.0	COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
WXD1_k127_1828924_1	118166.JH976537_gene4219	5.69e-08	65.0	COG0457@1|root,COG0457@2|Bacteria,1G1G9@1117|Cyanobacteria,1H889@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
WXD1_k127_1829122_1	292459.STH881	8.901e-144	464.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes	1239|Firmicutes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WXD1_k127_1829122_2	861299.J421_3049	6.133e-41	154.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
WXD1_k127_1829122_4	1210884.HG799465_gene12089	7.417e-14	77.0	COG0745@1|root,COG0745@2|Bacteria,2J1NZ@203682|Planctomycetes	203682|Planctomycetes	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1829122_3	886293.Sinac_5507	3.999e-34	136.0	COG0735@1|root,COG0735@2|Bacteria,2J1A1@203682|Planctomycetes	203682|Planctomycetes	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WXD1_k127_1829122_0	518766.Rmar_2149	8.57e-249	779.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
WXD1_k127_1839761_5	448385.sce2596	9.579e-129	442.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,42YQ0@68525|delta/epsilon subdivisions,2WTRV@28221|Deltaproteobacteria,2YUFX@29|Myxococcales	28221|Deltaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1839761_8	331869.BAL199_09188	6.756e-68	259.0	COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2TTCT@28211|Alphaproteobacteria,4BR40@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	ko:K18092	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05366	RC00752,RC00753	br01602,ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
WXD1_k127_1839761_0	1122222.AXWR01000035_gene216	7.931e-299	940.0	COG0058@1|root,COG0058@2|Bacteria,1WIR5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Alpha-glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
WXD1_k127_1839761_11	1454004.AW11_01694	7.142e-22	101.0	COG4251@1|root,COG4251@2|Bacteria,1N44A@1224|Proteobacteria	1224|Proteobacteria	T	PFAM KaiB domain	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
WXD1_k127_1839761_2	383372.Rcas_4148	6.381e-203	642.0	COG0467@1|root,COG0467@2|Bacteria,2G8TX@200795|Chloroflexi,376XI@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Circadian clock protein KaiC central region	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
WXD1_k127_1839761_9	861299.J421_5909	2.765e-61	232.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5909|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1839761_12	457396.CSBG_02782	4.406e-06	51.0	28Z2D@1|root,2ZKUW@2|Bacteria,1W52V@1239|Firmicutes,24SJF@186801|Clostridia,36PI2@31979|Clostridiaceae	186801|Clostridia	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
WXD1_k127_1839761_10	2340.JV46_22660	3.12e-41	162.0	COG4623@1|root,COG4623@2|Bacteria,1QUQJ@1224|Proteobacteria,1T218@1236|Gammaproteobacteria,1JBK3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WXD1_k127_1839761_6	937777.Deipe_3697	2.815e-87	296.0	COG0561@1|root,COG0561@2|Bacteria,1WJUR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WXD1_k127_1839761_1	404589.Anae109_1015	1.945e-278	887.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
WXD1_k127_1839761_7	379066.GAU_2908	5.435e-68	240.0	2BFIU@1|root,329CS@2|Bacteria,1ZV5H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1839761_4	379066.GAU_2909	1.692e-137	462.0	COG4319@1|root,COG4319@2|Bacteria,1ZUN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1839761_3	861299.J421_6111	1.943e-201	654.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1848954_3	379066.GAU_2584	4.15e-73	260.0	COG0006@1|root,COG0006@2|Bacteria,1ZSPF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
WXD1_k127_1848954_2	290397.Adeh_3438	1.881e-84	306.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WXD1_k127_1848954_1	558169.AGAV01000018_gene3490	1.212e-220	696.0	COG1228@1|root,COG1228@2|Bacteria,1W6UE@1239|Firmicutes,4HAQJ@91061|Bacilli	91061|Bacilli	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WXD1_k127_1848954_0	861299.J421_3571	0.0	1540.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
WXD1_k127_1848954_4	1278073.MYSTI_04029	7.688e-05	55.0	COG3055@1|root,COG5492@1|root,COG3055@2|Bacteria,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria	1224|Proteobacteria	N	PFAM Ig domain protein, group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566
WXD1_k127_1869687_0	1340493.JNIF01000004_gene1066	7.142e-180	579.0	COG1473@1|root,COG1473@2|Bacteria	2|Bacteria	S	N-acetyldiaminopimelate deacetylase activity	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WXD1_k127_1893926_4	1121013.P873_12790	8.036e-11	68.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,1RN46@1236|Gammaproteobacteria,1X3IZ@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
WXD1_k127_1893926_1	861299.J421_1521	8.893e-46	168.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WXD1_k127_1893926_0	861299.J421_0584	8.793e-271	852.0	COG0308@1|root,COG0308@2|Bacteria,1ZT68@142182|Gemmatimonadetes	2|Bacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WXD1_k127_1893926_3	1379698.RBG1_1C00001G0468	7.019e-32	131.0	COG2318@1|root,COG2318@2|Bacteria,2NRQN@2323|unclassified Bacteria	2|Bacteria	S	DinB family	yrdA	-	-	-	-	-	-	-	-	-	-	-	DinB
WXD1_k127_1893926_2	1379270.AUXF01000002_gene1455	1.503e-35	158.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1ZUC6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
WXD1_k127_1901304_0	861299.J421_4196	6.994e-182	572.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WXD1_k127_1901304_1	234267.Acid_0692	6.669e-97	327.0	COG0714@1|root,COG0714@2|Bacteria,3Y4G8@57723|Acidobacteria	57723|Acidobacteria	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WXD1_k127_1901304_2	502025.Hoch_6585	1.835e-22	108.0	COG1721@1|root,COG1721@2|Bacteria,1N8IQ@1224|Proteobacteria,42S2K@68525|delta/epsilon subdivisions,2WNA2@28221|Deltaproteobacteria,2YVGE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WXD1_k127_1903143_2	1239962.C943_00086	6.512e-99	338.0	COG4658@1|root,COG4658@2|Bacteria,4NESE@976|Bacteroidetes,47XQE@768503|Cytophagia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
WXD1_k127_1903143_1	765910.MARPU_10730	2.806e-132	435.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WXET@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_8,RnfC_N,SLBB
WXD1_k127_1903143_0	1379270.AUXF01000001_gene2161	3.926e-162	530.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
WXD1_k127_1904349_3	204669.Acid345_0471	4.663e-45	168.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1904349_1	1538295.JY96_13835	2.91e-106	367.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PD5J@1224|Proteobacteria,2W9PK@28216|Betaproteobacteria,1KMZ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
WXD1_k127_1904349_0	861299.J421_2344	6.711e-146	491.0	COG0744@1|root,COG0744@2|Bacteria,1ZSUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WXD1_k127_1904349_2	309807.SRU_0565	1.292e-58	215.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FK0U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Subtilase family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WXD1_k127_191986_1	502025.Hoch_2720	5.745e-05	53.0	COG3005@1|root,COG3005@2|Bacteria,1NJY9@1224|Proteobacteria	1224|Proteobacteria	C	12 heme-binding sites	cbcC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
WXD1_k127_191986_0	1191523.MROS_2048	3.126e-18	96.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
WXD1_k127_1925239_4	1379270.AUXF01000004_gene3272	5.811e-09	67.0	2A0X4@1|root,30P27@2|Bacteria,1ZUWS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_1925239_2	861299.J421_0057	3.767e-45	169.0	COG0782@1|root,COG0782@2|Bacteria,1ZTPD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WXD1_k127_1925239_0	1121104.AQXH01000001_gene1630	2.499e-141	462.0	COG0624@1|root,COG0624@2|Bacteria,4NJN0@976|Bacteroidetes,1IP8H@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WXD1_k127_1925239_1	861299.J421_2858	6.402e-96	326.0	COG3108@1|root,COG3108@2|Bacteria,1ZTME@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
WXD1_k127_194148_0	204669.Acid345_0465	0.0	1947.0	COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria,2JHJH@204432|Acidobacteriia	204432|Acidobacteriia	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
WXD1_k127_194148_1	204669.Acid345_0464	3.158e-66	231.0	COG1960@1|root,COG1960@2|Bacteria,3Y3T6@57723|Acidobacteria,2JIV6@204432|Acidobacteriia	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WXD1_k127_1988934_1	525904.Tter_2599	2.839e-59	217.0	COG0451@1|root,COG0451@2|Bacteria,2NPZU@2323|unclassified Bacteria	2|Bacteria	M	Male sterility protein	-	-	1.1.1.219,5.1.3.26	ko:K00091,ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WXD1_k127_1988934_4	1329516.JPST01000005_gene1446	9.136e-22	102.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,27C85@186824|Thermoactinomycetaceae	91061|Bacilli	K	'Cold-shock' DNA-binding domain	cspC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WXD1_k127_1988934_0	861299.J421_0826	7.659e-125	418.0	COG0076@1|root,COG0076@2|Bacteria,1ZU8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
WXD1_k127_1988934_2	379066.GAU_0167	1.307e-27	114.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
WXD1_k127_1988934_3	1242864.D187_002369	1.085e-26	117.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lip	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,DUF676,Lipase_2,YSIRK_signal
WXD1_k127_1990998_3	1297742.A176_06123	6.681e-09	57.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,42T7K@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,Response_reg
WXD1_k127_1990998_1	640511.BC1002_6472	1.663e-228	745.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,1JZSA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,Response_reg
WXD1_k127_1990998_2	953739.SVEN_0356	3.096e-09	70.0	COG1309@1|root,COG1309@2|Bacteria,2GP61@201174|Actinobacteria	201174|Actinobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
WXD1_k127_1990998_0	861299.J421_6152	0.0	1824.0	COG3459@1|root,COG3459@2|Bacteria,1ZTGS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
WXD1_k127_2011123_3	861299.J421_0207	4.306e-61	223.0	COG1191@1|root,COG1191@2|Bacteria,1ZSY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
WXD1_k127_2011123_7	861299.J421_0206	3.905e-16	90.0	COG0455@1|root,COG0455@2|Bacteria,1ZTW8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA
WXD1_k127_2011123_8	1304888.ATWF01000001_gene2586	1.862e-09	68.0	COG1419@1|root,COG1419@2|Bacteria,2GEJC@200930|Deferribacteres	200930|Deferribacteres	N	SRP54-type protein, GTPase domain	-	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
WXD1_k127_2011123_0	861299.J421_0204	1.149e-262	826.0	COG1298@1|root,COG1298@2|Bacteria,1ZT3Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
WXD1_k127_2011123_1	861299.J421_0203	1.741e-98	346.0	COG1377@1|root,COG1377@2|Bacteria,1ZT0W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	FlhB HrpN YscU SpaS Family	-	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
WXD1_k127_2011123_4	379066.GAU_0316	6.254e-48	184.0	COG1684@1|root,COG1684@2|Bacteria,1ZTQW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Bacterial export proteins, family 1	-	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
WXD1_k127_2011123_6	861299.J421_0201	2.5e-19	102.0	COG1987@1|root,COG1987@2|Bacteria,1ZTYI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Bacterial export proteins, family 3	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
WXD1_k127_2011123_2	861299.J421_0198	1.469e-78	277.0	COG1338@1|root,COG1338@2|Bacteria,1ZSX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO,FliP
WXD1_k127_2011123_5	1379270.AUXF01000002_gene1653	6.09e-28	119.0	COG1886@1|root,COG1886@2|Bacteria,1ZTVY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Type III flagellar switch regulator (C-ring) FliN C-term	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
WXD1_k127_2012371_1	861299.J421_2659	8.969e-204	657.0	COG0612@1|root,COG0612@2|Bacteria,1ZT1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_2012371_7	861299.J421_2721	6.49e-94	329.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_2721|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2012371_3	1123508.JH636439_gene1853	8.725e-121	426.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_2012371_13	632245.CLP_0353	1.104e-45	176.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,36IUU@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1648)	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
WXD1_k127_2012371_17	765420.OSCT_0097	2.743e-22	99.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	sdpR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
WXD1_k127_2012371_0	861299.J421_4071	1.459e-218	692.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	2|Bacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WXD1_k127_2012371_24	315749.Bcer98_0169	4.395e-05	54.0	COG4194@1|root,COG4194@2|Bacteria,1V3Z3@1239|Firmicutes,4HHRK@91061|Bacilli,1ZG9F@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
WXD1_k127_2012371_16	861299.J421_0164	3.258e-28	125.0	2F57Y@1|root,33XUE@2|Bacteria,1ZTSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2012371_14	861299.J421_0165	1.125e-42	171.0	COG0745@1|root,COG0745@2|Bacteria,1ZTPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WXD1_k127_2012371_19	1123354.AUDR01000019_gene155	1.819e-12	74.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,2VU2S@28216|Betaproteobacteria,1KT6P@119069|Hydrogenophilales	119069|Hydrogenophilales	NOU	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
WXD1_k127_2012371_5	439235.Dalk_0644	1.424e-105	378.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,42MHW@68525|delta/epsilon subdivisions,2WNU5@28221|Deltaproteobacteria,2MPZW@213118|Desulfobacterales	28221|Deltaproteobacteria	N	Flagellar hook-associated protein 2 N-terminus	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
WXD1_k127_2012371_11	1089548.KI783301_gene2951	1.052e-64	236.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,4H9UA@91061|Bacilli,3WF89@539002|Bacillales incertae sedis	91061|Bacilli	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	flaA	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WXD1_k127_2012371_21	1123367.C666_10370	3.086e-10	66.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KVE6@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Sigma54_activat
WXD1_k127_2012371_9	379066.GAU_0295	4.975e-79	286.0	COG1360@1|root,COG1360@2|Bacteria,1ZT7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Membrane MotB of proton-channel complex MotA/MotB	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
WXD1_k127_2012371_4	379066.GAU_0296	1.871e-112	384.0	COG1291@1|root,COG1291@2|Bacteria,1ZT30@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
WXD1_k127_2012371_2	760192.Halhy_2413	3.364e-125	415.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WXD1_k127_2012371_18	379066.GAU_0298	2.309e-14	81.0	COG1551@1|root,COG1551@2|Bacteria,1ZU3N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Global regulator protein family	-	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
WXD1_k127_2012371_10	861299.J421_0220	4.537e-70	256.0	COG1256@1|root,COG4786@1|root,COG1256@2|Bacteria,COG4786@2|Bacteria,1ZTDI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Flagella basal body rod protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WXD1_k127_2012371_20	379066.GAU_0300	2.976e-10	68.0	2CD1W@1|root,342SW@2|Bacteria,1ZTZN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
WXD1_k127_2012371_23	371042.NG99_11665	1.306e-05	56.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,1RPGY@1236|Gammaproteobacteria,3X69F@551|Erwinia	1236|Gammaproteobacteria	N	Peptidoglycan hydrolase flgJ (Muramidase	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
WXD1_k127_2012371_8	861299.J421_0217	1.527e-89	307.0	COG1706@1|root,COG1706@2|Bacteria,1ZT3H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
WXD1_k127_2012371_15	379066.GAU_0303	8.34e-33	138.0	COG2063@1|root,COG2063@2|Bacteria,1ZTKF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	-	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
WXD1_k127_2012371_22	379066.GAU_0304	1.515e-09	67.0	COG1261@1|root,COG1261@2|Bacteria,1ZU6J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	-	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
WXD1_k127_2012371_6	861299.J421_0214	1.556e-95	326.0	COG4786@1|root,COG4786@2|Bacteria,1ZTGP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Flagella basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WXD1_k127_2012371_12	861299.J421_0213	1.007e-57	209.0	COG4786@1|root,COG4786@2|Bacteria,1ZTQ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Flagella basal body rod protein	-	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WXD1_k127_2033283_6	1234364.AMSF01000001_gene2383	5.064e-05	49.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1X3X2@135614|Xanthomonadales	135614|Xanthomonadales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
WXD1_k127_2033283_1	861299.J421_3068	3.531e-74	265.0	COG0275@1|root,COG0275@2|Bacteria,1ZT4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WXD1_k127_2033283_4	1123373.ATXI01000011_gene1095	1.696e-22	103.0	COG2001@1|root,COG2001@2|Bacteria,2GGT9@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WXD1_k127_2033283_2	1280390.CBQR020000068_gene1422	1.34e-51	198.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli,26R0X@186822|Paenibacillaceae	91061|Bacilli	I	to YegS from E. coli	dagK	GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
WXD1_k127_2033283_7	9483.ENSCJAP00000002559	6.741e-05	56.0	COG0652@1|root,KOG0546@2759|Eukaryota,38D8M@33154|Opisthokonta,3B9VI@33208|Metazoa,3CWEB@33213|Bilateria,47YXU@7711|Chordata,48VNN@7742|Vertebrata,3JE35@40674|Mammalia,35DVC@314146|Euarchontoglires,4MHMN@9443|Primates	33208|Metazoa	O	isomerase D	PPID	GO:0000122,GO:0000413,GO:0002791,GO:0002793,GO:0003674,GO:0003755,GO:0003824,GO:0005102,GO:0005488,GO:0005515,GO:0005527,GO:0005528,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005739,GO:0005829,GO:0006355,GO:0006357,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010941,GO:0010942,GO:0016018,GO:0016032,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019058,GO:0019076,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0022607,GO:0030331,GO:0030544,GO:0031072,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032879,GO:0032880,GO:0033218,GO:0034389,GO:0034644,GO:0035257,GO:0035258,GO:0035890,GO:0035891,GO:0036211,GO:0040011,GO:0042277,GO:0042391,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043900,GO:0043902,GO:0043903,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045069,GO:0045070,GO:0045892,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048524,GO:0050708,GO:0050714,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051222,GO:0051223,GO:0051252,GO:0051253,GO:0051427,GO:0051701,GO:0051704,GO:0051716,GO:0051879,GO:0051881,GO:0052126,GO:0052192,GO:0060255,GO:0060548,GO:0061077,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070141,GO:0070201,GO:0071214,GO:0071478,GO:0071482,GO:0071492,GO:0071704,GO:0071840,GO:0080090,GO:0090087,GO:0097159,GO:0104004,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1903530,GO:1903532,GO:1903900,GO:1903902,GO:1904951,GO:2000112,GO:2000113,GO:2001141	2.3.1.234,5.2.1.8	ko:K01409,ko:K05864,ko:K09566	ko04217,ko04218,map04217,map04218	-	R10648	RC00070,RC00416	ko00000,ko00001,ko01000,ko03016,ko03041,ko03110	-	-	-	Pro_isomerase,TPR_2,TPR_7
WXD1_k127_2033283_0	1379270.AUXF01000003_gene3431	1.307e-109	378.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	2|Bacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WXD1_k127_2033283_5	1090318.ATTI01000001_gene2224	5.301e-08	63.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2K05M@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_2033283_3	861299.J421_0916	2.033e-42	160.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_2057972_0	379066.GAU_1414	1.485e-43	164.0	COG2201@1|root,COG2201@2|Bacteria,1ZUFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WXD1_k127_2057972_1	1379270.AUXF01000005_gene679	2.526e-42	173.0	2DUTE@1|root,33S5W@2|Bacteria,1ZSMI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2057972_4	1121438.JNJA01000020_gene2719	5.252e-08	61.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2MB9T@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WXD1_k127_2057972_2	479433.Caci_3277	1.072e-40	161.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_2057972_3	1124780.ANNU01000013_gene3827	6.932e-11	70.0	COG1917@1|root,COG1917@2|Bacteria,4PC6H@976|Bacteroidetes,47WW5@768503|Cytophagia	976|Bacteroidetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_210213_8	215803.DB30_1971	4.652e-10	69.0	COG0457@1|root,COG0457@2|Bacteria,1Q2MK@1224|Proteobacteria,43886@68525|delta/epsilon subdivisions,2X3HX@28221|Deltaproteobacteria,2YW6E@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_210213_9	1379270.AUXF01000004_gene3124	2.842e-06	56.0	2FDPQ@1|root,345QV@2|Bacteria,1ZU3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_210213_1	1123368.AUIS01000009_gene2441	2.473e-96	325.0	COG4914@1|root,COG4914@2|Bacteria,1QX3W@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204,NTP_transf_5
WXD1_k127_210213_4	1173027.Mic7113_2540	1.58e-75	261.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
WXD1_k127_210213_2	861299.J421_2733	7.563e-82	285.0	COG3569@1|root,COG3569@2|Bacteria	2|Bacteria	L	DNA topoisomerase type I activity	MA20_25110	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
WXD1_k127_210213_0	477974.Daud_1879	1.171e-234	757.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,2608V@186807|Peptococcaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WXD1_k127_210213_7	491915.Aflv_1219	2.911e-13	72.0	COG2608@1|root,COG2608@2|Bacteria,1VERB@1239|Firmicutes,4HNP0@91061|Bacilli,21VWF@150247|Anoxybacillus	91061|Bacilli	P	Heavy-metal-associated domain	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
WXD1_k127_210213_5	1219084.AP014508_gene505	1.135e-73	279.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WXD1_k127_210213_3	1219084.AP014508_gene506	1.63e-81	294.0	COG1175@1|root,COG1175@2|Bacteria,2GC8J@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K17242	ko02010,map02010	M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.39	-	-	BPD_transp_1
WXD1_k127_210213_6	1219084.AP014508_gene507	6.924e-41	163.0	COG1653@1|root,COG1653@2|Bacteria,2GCPM@200918|Thermotogae	200918|Thermotogae	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WXD1_k127_2135250_1	379066.GAU_0858	4.703e-18	92.0	2C30C@1|root,2ZV1M@2|Bacteria,1ZV6Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2135866_18	365046.Rta_17280	4.359e-54	192.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria,4A9M8@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	risS	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,RisS_PPD
WXD1_k127_2135866_9	404589.Anae109_4110	3.769e-98	325.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2X64M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdopterin,Molydop_binding
WXD1_k127_2135866_1	1191523.MROS_1774	2.823e-185	592.0	COG0243@1|root,COG0243@2|Bacteria	2|Bacteria	C	molybdopterin cofactor binding	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
WXD1_k127_2135866_15	1191523.MROS_1775	1.257e-65	228.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nrfC	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809	-	ko:K04014,ko:K08353,ko:K08358,ko:K16293	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10149,R10150	RC02823,RC03109	ko00000,ko00001,ko02000	5.A.3.10,5.A.3.5	-	iUMNK88_1353.UMNK88_4933	Fer4,Fer4_11,Fer4_3,Fer4_4
WXD1_k127_2135866_12	404589.Anae109_4106	5.426e-82	283.0	COG3301@1|root,COG3301@2|Bacteria,1MXQ9@1224|Proteobacteria,42NE8@68525|delta/epsilon subdivisions,2WSJ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
WXD1_k127_2135866_19	945713.IALB_1660	1.187e-52	193.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WXD1_k127_2135866_20	404589.Anae109_4107	1.807e-50	199.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,42QRV@68525|delta/epsilon subdivisions,2WMUE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WXD1_k127_2135866_23	1121459.AQXE01000017_gene2148	7.735e-26	123.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria,2MB9Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Molybdopterin guanine dinucleotide synthesis protein B	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
WXD1_k127_2135866_3	861299.J421_5728	2.073e-131	460.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
WXD1_k127_2135866_5	861299.J421_0489	1.09e-119	407.0	COG0642@1|root,COG3614@1|root,COG2205@2|Bacteria,COG3614@2|Bacteria	2|Bacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_2135866_10	522373.Smlt3255	1.924e-84	292.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria,1XCEX@135614|Xanthomonadales	135614|Xanthomonadales	K	Transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WXD1_k127_2135866_2	929713.NIASO_16370	3.96e-169	557.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
WXD1_k127_2135866_7	1379270.AUXF01000005_gene646	6.252e-115	391.0	COG2070@1|root,COG2070@2|Bacteria,1ZUN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
WXD1_k127_2135866_22	1242864.D187_002986	3.12e-33	138.0	COG2050@1|root,COG2050@2|Bacteria,1RHAN@1224|Proteobacteria,43157@68525|delta/epsilon subdivisions,2WWIW@28221|Deltaproteobacteria,2YVGQ@29|Myxococcales	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
WXD1_k127_2135866_14	861299.J421_0489	2.674e-70	262.0	COG0642@1|root,COG3614@1|root,COG2205@2|Bacteria,COG3614@2|Bacteria	2|Bacteria	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_2135866_4	644801.Psest_4140	6.704e-128	433.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1Z1SV@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WXD1_k127_2135866_11	670487.Ocepr_0960	6.865e-83	283.0	COG0428@1|root,COG0428@2|Bacteria,1WIUI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	divalent heavy-metal cations transporter	-	-	-	-	-	-	-	-	-	-	-	-	Zip
WXD1_k127_2135866_24	1128427.KB904821_gene2948	5.743e-25	121.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1HAPE@1150|Oscillatoriales	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WXD1_k127_2135866_26	1121448.DGI_2106	1.593e-14	85.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,42UKB@68525|delta/epsilon subdivisions,2WQD0@28221|Deltaproteobacteria,2MDAN@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WXD1_k127_2135866_17	396588.Tgr7_2368	1.176e-56	224.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,1RN4M@1236|Gammaproteobacteria,1X19U@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2135866_21	243231.GSU1976	1.804e-38	161.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,42RYD@68525|delta/epsilon subdivisions,2X5EZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_2135866_8	323848.Nmul_A2670	1.046e-99	351.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VJQV@28216|Betaproteobacteria,3720X@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	AMP-dependent synthetase	fadD	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WXD1_k127_2135866_6	1408224.SAMCCGM7_c1711	4.011e-116	389.0	COG0171@1|root,COG0171@2|Bacteria,1QHZ4@1224|Proteobacteria,2U1JK@28211|Alphaproteobacteria,4BA80@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WXD1_k127_2135866_0	1502851.FG93_00834	2.19e-190	616.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,3JWPP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
WXD1_k127_2135866_16	1382359.JIAL01000001_gene915	1.747e-60	225.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Lipase_GDSL_2
WXD1_k127_2135866_27	926569.ANT_20020	2.889e-09	69.0	COG0236@1|root,COG0236@2|Bacteria,2G7GE@200795|Chloroflexi	200795|Chloroflexi	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
WXD1_k127_2135866_13	443152.MDG893_06144	8.526e-73	267.0	COG2244@1|root,COG2244@2|Bacteria,1QUX9@1224|Proteobacteria,1RYR5@1236|Gammaproteobacteria,46A8N@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
WXD1_k127_2135866_25	1121101.HMPREF1532_00139	9.477e-20	101.0	COG0110@1|root,COG0110@2|Bacteria,4NMHW@976|Bacteroidetes,2FPDD@200643|Bacteroidia,4AMEE@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
WXD1_k127_215026_0	714943.Mucpa_4573	1.306e-89	307.0	COG3858@1|root,COG3858@2|Bacteria	2|Bacteria	S	chitin binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
WXD1_k127_215026_1	1173025.GEI7407_2390	1.867e-80	282.0	COG1409@1|root,COG1409@2|Bacteria,1G30N@1117|Cyanobacteria,1H7KH@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WXD1_k127_215026_2	696281.Desru_2564	4.359e-20	100.0	COG5401@1|root,COG5401@2|Bacteria,1TQX6@1239|Firmicutes,249MF@186801|Clostridia,262UB@186807|Peptococcaceae	186801|Clostridia	S	PFAM Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
WXD1_k127_2160594_0	1379270.AUXF01000002_gene1177	1.879e-125	417.0	COG2204@1|root,COG2204@2|Bacteria,1ZUNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_2160594_1	1408428.JNJP01000045_gene1976	3.117e-29	133.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2M8UQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_3_2
WXD1_k127_2160594_2	1191523.MROS_0988	1.97e-25	114.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_2163054_2	1242864.D187_000759	3.237e-41	167.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,431H7@68525|delta/epsilon subdivisions,2WWTH@28221|Deltaproteobacteria,2Z202@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
WXD1_k127_2163054_1	983917.RGE_12890	1.78e-62	233.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
WXD1_k127_2163054_0	1386089.N865_20940	2.906e-75	271.0	COG1801@1|root,COG1801@2|Bacteria,2IH5N@201174|Actinobacteria,4FID2@85021|Intrasporangiaceae	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WXD1_k127_2163054_3	338969.Rfer_0293	3.824e-23	108.0	COG3945@1|root,COG3945@2|Bacteria,1N12K@1224|Proteobacteria,2VUPY@28216|Betaproteobacteria,4AENF@80864|Comamonadaceae	28216|Betaproteobacteria	T	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
WXD1_k127_2179488_0	1501230.ET33_19585	9.827e-236	749.0	COG1643@1|root,COG1643@2|Bacteria,1TPET@1239|Firmicutes,4HE8W@91061|Bacilli,26U7B@186822|Paenibacillaceae	91061|Bacilli	L	ATP-dependent helicase	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
WXD1_k127_2179488_3	1047013.AQSP01000142_gene167	4.834e-17	94.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	ywhL	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
WXD1_k127_2179488_4	1218103.CIN01S_04_01570	1.252e-14	87.0	COG3637@1|root,COG3637@2|Bacteria,4NVT2@976|Bacteroidetes,1I8VN@117743|Flavobacteriia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
WXD1_k127_2213242_1	518766.Rmar_1661	5.19e-174	555.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1FJ49@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
WXD1_k127_2213242_6	99598.Cal7507_2219	1.945e-11	74.0	COG0760@1|root,COG0760@2|Bacteria,1G1TT@1117|Cyanobacteria,1HRQR@1161|Nostocales	1117|Cyanobacteria	O	PFAM PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase
WXD1_k127_2213242_7	66429.JOFL01000007_gene2314	1.429e-07	64.0	COG0189@1|root,COG0189@2|Bacteria	2|Bacteria	HJ	Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	RimK
WXD1_k127_2213242_4	1254432.SCE1572_01775	2.205e-73	268.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
WXD1_k127_2213242_0	977880.RALTA_A2173	5.633e-212	700.0	COG0664@1|root,COG2274@1|root,COG0664@2|Bacteria,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VP2B@28216|Betaproteobacteria,1K0FE@119060|Burkholderiaceae	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39,cNMP_binding
WXD1_k127_2213242_5	118173.KB235914_gene1552	1.872e-13	83.0	COG1566@1|root,COG1566@2|Bacteria,1GQC6@1117|Cyanobacteria	1117|Cyanobacteria	V	Alternative locus ID	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
WXD1_k127_2213242_2	1128421.JAGA01000003_gene3129	6.975e-151	489.0	COG0025@1|root,COG0025@2|Bacteria	2|Bacteria	P	sodium:proton antiporter activity	sod22	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WXD1_k127_2213242_3	1089551.KE386572_gene120	9.597e-92	329.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2U5X1@28211|Alphaproteobacteria,4BRDK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
WXD1_k127_2239815_1	555088.DealDRAFT_0355	3.399e-69	258.0	COG3857@1|root,COG3857@2|Bacteria,1TS95@1239|Firmicutes,24F8M@186801|Clostridia	186801|Clostridia	L	PD-(D/E)XK nuclease superfamily	-	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
WXD1_k127_2239815_0	1120971.AUCA01000065_gene1882	2.755e-147	514.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,277XR@186823|Alicyclobacillaceae	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WXD1_k127_2244166_3	231434.JQJH01000001_gene1873	2.247e-40	166.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,3NAA7@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	MA20_07390	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WXD1_k127_2244166_5	1379698.RBG1_1C00001G0796	1.467e-29	124.0	COG1956@1|root,COG1956@2|Bacteria	2|Bacteria	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
WXD1_k127_2244166_2	1236973.JCM9157_4896	2.031e-50	187.0	COG1878@1|root,COG1878@2|Bacteria,1U801@1239|Firmicutes,4HDQ3@91061|Bacilli,1ZD77@1386|Bacillus	91061|Bacilli	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
WXD1_k127_2244166_1	756272.Plabr_3272	1.538e-89	326.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,2IX8Z@203682|Planctomycetes	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	BTAD,CHASE3,DUF4118,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WXD1_k127_2244166_0	383372.Rcas_0232	1.768e-134	439.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,376QF@32061|Chloroflexia	32061|Chloroflexia	G	PFAM peptidase M18 aminopeptidase I	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WXD1_k127_2244166_4	1379270.AUXF01000001_gene2574	2.225e-36	144.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
WXD1_k127_2250174_4	1379270.AUXF01000001_gene2739	0.0001992	50.0	COG4447@1|root,COG4447@2|Bacteria,1ZUBH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WXD1_k127_2250174_3	639030.JHVA01000001_gene737	8.723e-38	166.0	COG4846@1|root,COG4846@2|Bacteria,3Y4ZF@57723|Acidobacteria,2JMY8@204432|Acidobacteriia	204432|Acidobacteriia	O	Protein of unknown function (DUF1453)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1453
WXD1_k127_2250174_1	204669.Acid345_1504	6.749e-146	476.0	COG2195@1|root,COG2195@2|Bacteria,3Y6CZ@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WXD1_k127_2250174_0	1265505.ATUG01000001_gene3606	2.829e-194	620.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,1R781@1224|Proteobacteria,42MUJ@68525|delta/epsilon subdivisions,2WJUE@28221|Deltaproteobacteria,2MHQA@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
WXD1_k127_2250174_2	880073.Calab_2482	5.695e-44	171.0	COG0534@1|root,COG0534@2|Bacteria,2NPFE@2323|unclassified Bacteria	2|Bacteria	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	ANKH,MatE
WXD1_k127_2256607_1	929712.KI912613_gene874	1.119e-39	160.0	COG5340@1|root,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2256607_0	378806.STAUR_2988	4.662e-176	574.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YU05@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WXD1_k127_2256607_2	861299.J421_0084	7.238e-07	51.0	COG0204@1|root,COG0204@2|Bacteria,1ZSY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WXD1_k127_2265399_3	483219.LILAB_07495	1.919e-24	109.0	2E3Q4@1|root,32YN3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2265399_2	1242864.D187_008427	8.343e-56	208.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	1.14.14.47	ko:K00491,ko:K21572	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	-	R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000,ko02000	8.A.46.1,8.A.46.3	-	-	DUF1990,EF-hand_5,FAD_binding_6,Fer2_BFD,NAD_binding_1,NAD_binding_10,NO_synthase,SusD-like_3,SusD_RagB
WXD1_k127_2265399_1	1242864.D187_008428	2.745e-57	216.0	COG3918@1|root,COG3918@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
WXD1_k127_2265399_0	1121430.JMLG01000013_gene1868	4.79e-138	449.0	COG1415@1|root,COG1415@2|Bacteria,1UWH7@1239|Firmicutes,24DPJ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF763)	-	-	-	ko:K09003	-	-	-	-	ko00000	-	-	-	DUF763
WXD1_k127_2265742_1	1239962.C943_04638	4.409e-67	241.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
WXD1_k127_2265742_0	1123242.JH636434_gene5497	1.418e-205	661.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WXD1_k127_2265742_2	1144275.COCOR_05143	1.137e-34	154.0	COG1752@1|root,COG1752@2|Bacteria,1NCAA@1224|Proteobacteria,42ZIY@68525|delta/epsilon subdivisions,2WUVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WXD1_k127_2269956_10	1210884.HG799466_gene12661	1.796e-17	84.0	COG4191@1|root,COG4191@2|Bacteria	1210884.HG799466_gene12661|-	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2269956_1	671143.DAMO_1821	2.645e-120	400.0	COG2201@1|root,COG2201@2|Bacteria,2NNUY@2323|unclassified Bacteria	2|Bacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WXD1_k127_2269956_3	1395571.TMS3_0111950	4.91e-108	371.0	COG2172@1|root,COG2208@1|root,COG3437@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	response regulator	rsbU	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
WXD1_k127_2269956_9	1005395.CSV86_14581	2.291e-23	102.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,1S9QR@1236|Gammaproteobacteria,1YZ4K@136845|Pseudomonas putida group	1236|Gammaproteobacteria	T	STAS domain	rsbV	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
WXD1_k127_2269956_7	1245471.PCA10_13920	4.626e-41	165.0	COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,1S2V1@1236|Gammaproteobacteria,1YDMY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
WXD1_k127_2269956_8	1003200.AXXA_13164	1.091e-29	134.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2VR2W@28216|Betaproteobacteria,3T71I@506|Alcaligenaceae	28216|Betaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
WXD1_k127_2269956_4	1210884.HG799474_gene15200	4.785e-77	275.0	COG1352@1|root,COG1352@2|Bacteria,2IZ6C@203682|Planctomycetes	203682|Planctomycetes	NT	Methylase of chemotaxis methyl-accepting	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WXD1_k127_2269956_2	1005048.CFU_0924	6.05e-115	391.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,476K0@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	PFAM HAMP domain, Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406,ko:K05875	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
WXD1_k127_2269956_5	1210884.HG799474_gene15192	1.363e-45	175.0	COG0835@1|root,COG0835@2|Bacteria,2J076@203682|Planctomycetes	203682|Planctomycetes	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WXD1_k127_2269956_0	114615.BRADO1822	6.737e-167	547.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,3JWUA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Function of homologous gene experimentally demonstrated in an other organism	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
WXD1_k127_2269956_6	1000565.METUNv1_02607	6.398e-42	156.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VSDT@28216|Betaproteobacteria,2KWAN@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WXD1_k127_2269956_11	90813.JQMT01000001_gene41	0.0001375	50.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K20976	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt
WXD1_k127_2275142_3	1343739.PAP_04525	4.204e-27	117.0	COG2201@1|root,arCOG02382@2157|Archaea,2XUKR@28890|Euryarchaeota,2433H@183968|Thermococci	183968|Thermococci	N	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WXD1_k127_2275142_2	926561.KB900623_gene1059	4.301e-34	139.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,24HH7@186801|Clostridia,3WAQN@53433|Halanaerobiales	186801|Clostridia	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
WXD1_k127_2275142_1	861299.J421_3062	2.809e-71	252.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WXD1_k127_2275142_0	1379270.AUXF01000005_gene674	3.299e-121	408.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
WXD1_k127_2275142_4	1379270.AUXF01000005_gene673	7.768e-26	112.0	COG0593@1|root,COG0593@2|Bacteria,1ZUFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bacterial dnaA  protein	-	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA
WXD1_k127_2277706_1	1121439.dsat_2692	4.075e-20	100.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WXD1_k127_2277706_0	640132.Srot_2241	3.807e-130	432.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria	201174|Actinobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
WXD1_k127_2288513_3	1379270.AUXF01000005_gene667	5.986e-51	191.0	COG2204@1|root,COG2204@2|Bacteria,1ZTMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WXD1_k127_2288513_8	1442599.JAAN01000021_gene2214	7.703e-12	76.0	COG0835@1|root,COG0835@2|Bacteria,1R9IA@1224|Proteobacteria,1RXTZ@1236|Gammaproteobacteria,1X6ET@135614|Xanthomonadales	135614|Xanthomonadales	NT	chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WXD1_k127_2288513_2	429009.Adeg_1604	3.186e-81	283.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,42F72@68295|Thermoanaerobacterales	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WXD1_k127_2288513_5	1379270.AUXF01000005_gene663	8.499e-38	148.0	COG0597@1|root,COG0597@2|Bacteria,1ZTWA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WXD1_k127_2288513_0	861299.J421_3048	0.0	1107.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WXD1_k127_2288513_1	379066.GAU_1398	1.752e-108	358.0	COG0005@1|root,COG0005@2|Bacteria,1ZUII@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WXD1_k127_2288513_9	891968.Anamo_0384	6.142e-07	62.0	COG3599@1|root,COG3599@2|Bacteria,3TBCR@508458|Synergistetes	508458|Synergistetes	D	DivIVA domain	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
WXD1_k127_2288513_4	665571.STHERM_c17100	9.527e-42	161.0	COG0325@1|root,COG0325@2|Bacteria,2J71S@203691|Spirochaetes	203691|Spirochaetes	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WXD1_k127_2288513_7	633149.Bresu_3233	4.19e-28	115.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2TRS4@28211|Alphaproteobacteria,2KEZT@204458|Caulobacterales	204458|Caulobacterales	M	glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
WXD1_k127_2288513_6	391600.ABRU01000005_gene1626	2.958e-33	131.0	COG1215@1|root,COG1215@2|Bacteria,1QVG6@1224|Proteobacteria,2TWF3@28211|Alphaproteobacteria,2KFY3@204458|Caulobacterales	204458|Caulobacterales	M	Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WXD1_k127_2293536_4	1288963.ADIS_1732	4.277e-30	128.0	28NN4@1|root,2ZBNJ@2|Bacteria,4NMVI@976|Bacteroidetes,47PGF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2293536_1	861299.J421_2173	1.802e-43	177.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_2173|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2293536_2	861299.J421_1020	2.774e-42	165.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
WXD1_k127_2293536_3	1120960.ATXG01000021_gene3218	3.012e-30	139.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,2GMQS@201174|Actinobacteria	201174|Actinobacteria	E	peptidase M36	-	-	-	ko:K01417	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,Peptidase_M36
WXD1_k127_2293536_0	1123234.AUKI01000019_gene551	8.282e-60	234.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1HZQR@117743|Flavobacteriia	976|Bacteroidetes	K	COGs COG5616 integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC3,Guanylate_cyc,HTH_18,TPR_8
WXD1_k127_2297876_0	861299.J421_3349	4.073e-181	574.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WXD1_k127_2305882_1	1304874.JAFY01000007_gene1685	2.232e-81	282.0	COG1180@1|root,COG1180@2|Bacteria,3T9PA@508458|Synergistetes	508458|Synergistetes	C	TIGRFAM glycyl-radical enzyme activating protein family	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
WXD1_k127_2305882_0	1121422.AUMW01000009_gene3340	0.0	1099.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,2618A@186807|Peptococcaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
WXD1_k127_2305882_3	1166018.FAES_4525	1.478e-54	200.0	2DBMF@1|root,2Z9YG@2|Bacteria,4NPRW@976|Bacteroidetes,47Q6I@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2305882_2	1540221.JQNI01000002_gene2810	2.825e-76	258.0	COG0655@1|root,COG0655@2|Bacteria,1WMF7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Belongs to the WrbA family	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
WXD1_k127_2315770_1	861299.J421_0071	1.994e-179	573.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	MA20_07280	-	2.7.13.3	ko:K03407,ko:K12257	ko02020,ko02024,ko02030,ko03060,ko03070,map02020,map02024,map02030,map03060,map03070	M00335,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	2.A.6.4	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
WXD1_k127_2315770_2	861299.J421_0070	2.051e-128	420.0	COG1352@1|root,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WXD1_k127_2315770_5	63737.Npun_F3540	1.958e-53	194.0	COG2201@1|root,COG2201@2|Bacteria,1G6B8@1117|Cyanobacteria,1HNNM@1161|Nostocales	1117|Cyanobacteria	NT	CheB methylesterase	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest
WXD1_k127_2315770_3	861299.J421_0068	1.524e-124	430.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
WXD1_k127_2315770_4	1210884.HG799468_gene13551	3.271e-92	329.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_2315770_8	313612.L8106_06284	1.182e-06	61.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1G0TN@1117|Cyanobacteria,1H8RU@1150|Oscillatoriales	1117|Cyanobacteria	D	exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
WXD1_k127_2315770_0	861299.J421_2945	2.993e-181	608.0	COG1196@1|root,COG1196@2|Bacteria,1ZSY1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
WXD1_k127_2315770_6	1191523.MROS_1956	7.496e-52	207.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprN	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WXD1_k127_2315770_7	379066.GAU_1193	1.464e-18	101.0	2F30N@1|root,33VVY@2|Bacteria,1ZTT9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2333559_0	861299.J421_2981	1.195e-235	756.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1ZT1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RadC
WXD1_k127_2333559_1	379066.GAU_1255	5.321e-136	440.0	2CD20@1|root,2Z7SQ@2|Bacteria,1ZTFE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2337950_3	1410634.JHVD01000007_gene1054	7.569e-18	83.0	2B542@1|root,31XXJ@2|Bacteria,2HZHK@201174|Actinobacteria,4DSU8@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2337950_2	379066.GAU_0633	7.462e-47	181.0	COG0632@1|root,COG0632@2|Bacteria,1ZTR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WXD1_k127_2337950_1	861299.J421_2580	7.808e-56	205.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WXD1_k127_2337950_0	861299.J421_2581	2.377e-87	295.0	COG0217@1|root,COG0217@2|Bacteria,1ZTF4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WXD1_k127_2341784_4	1279009.ADICEAN_02600	2.722e-66	238.0	COG2374@1|root,COG3204@1|root,COG2374@2|Bacteria,COG3204@2|Bacteria,4NURG@976|Bacteroidetes,47P25@768503|Cytophagia	976|Bacteroidetes	G	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WXD1_k127_2341784_7	379066.GAU_0459	2.315e-34	137.0	COG1846@1|root,COG1846@2|Bacteria,1ZU5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WXD1_k127_2341784_5	330214.NIDE0008	1.548e-40	155.0	COG2259@1|root,COG2259@2|Bacteria,3J13I@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
WXD1_k127_2341784_2	861299.J421_6089	1.377e-128	428.0	COG1073@1|root,COG1680@1|root,COG1073@2|Bacteria,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Beta-lactamase,DUF3471,Hydrolase_4
WXD1_k127_2341784_0	517418.Ctha_1886	1.04e-275	864.0	COG4147@1|root,COG4147@2|Bacteria,1FDIY@1090|Chlorobi	1090|Chlorobi	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
WXD1_k127_2341784_9	1121889.AUDM01000004_gene2534	6.838e-28	117.0	COG4327@1|root,COG4327@2|Bacteria,4NSV7@976|Bacteroidetes,1I3X5@117743|Flavobacteriia,2NX5R@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
WXD1_k127_2341784_8	379066.GAU_2069	3.612e-30	132.0	2BWJK@1|root,3480I@2|Bacteria,1ZU2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2341784_6	861299.J421_2364	1.085e-37	148.0	COG0723@1|root,COG0723@2|Bacteria,1ZU0N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
WXD1_k127_2341784_1	570967.JMLV01000008_gene1306	5.57e-136	443.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,2JPVS@204441|Rhodospirillales	204441|Rhodospirillales	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
WXD1_k127_2341784_3	234267.Acid_7851	4.412e-79	282.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,3Y6UN@57723|Acidobacteria	57723|Acidobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2350959_0	760192.Halhy_3247	3.49e-144	473.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WXD1_k127_2350959_4	1415756.JQMY01000001_gene3441	9.2e-10	71.0	COG0642@1|root,COG2205@2|Bacteria,1N5YU@1224|Proteobacteria,2TTXK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WXD1_k127_2350959_1	1089550.ATTH01000001_gene1334	5.918e-87	305.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1FIS4@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_2350959_2	1313421.JHBV01000043_gene3062	5.839e-36	142.0	COG4430@1|root,COG4430@2|Bacteria,4NQHR@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
WXD1_k127_2350959_3	1219045.BV98_001402	8.144e-20	92.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria,2UFVS@28211|Alphaproteobacteria,2K5XE@204457|Sphingomonadales	204457|Sphingomonadales	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
WXD1_k127_2365129_0	1260251.SPISAL_01030	3.381e-228	724.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,1WVV2@135613|Chromatiales	135613|Chromatiales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
WXD1_k127_237354_0	1118054.CAGW01000062_gene2251	8.263e-76	261.0	COG0123@1|root,COG0123@2|Bacteria,1TQF7@1239|Firmicutes,4HBTF@91061|Bacilli,26UV4@186822|Paenibacillaceae	91061|Bacilli	BQ	histone deacetylase	acuC	-	-	ko:K04768	-	-	-	-	ko00000	-	-	iYO844.BSU29710	Hist_deacetyl
WXD1_k127_237354_1	266117.Rxyl_1013	1.998e-39	156.0	COG0517@1|root,COG4747@1|root,COG0517@2|Bacteria,COG4747@2|Bacteria,2GSAR@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	ACT,CBS
WXD1_k127_237354_3	1279038.KB907344_gene3564	0.0001317	53.0	COG2207@1|root,COG2207@2|Bacteria,1N4T1@1224|Proteobacteria,2U7YQ@28211|Alphaproteobacteria,2JURA@204441|Rhodospirillales	204441|Rhodospirillales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WXD1_k127_237354_2	1121377.KB906422_gene3667	1.09e-05	56.0	COG3629@1|root,COG3899@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,1WKSF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
WXD1_k127_2428087_0	861299.J421_2134	2.573e-124	412.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	socC	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WXD1_k127_2428087_3	926550.CLDAP_08400	4.224e-31	142.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	2|Bacteria	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12
WXD1_k127_2428087_6	1173022.Cri9333_2639	2.736e-09	63.0	2C1A8@1|root,32R8C@2|Bacteria,1G7IA@1117|Cyanobacteria,1HDSA@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2428087_1	861299.J421_2168	2.721e-81	279.0	COG0454@1|root,COG0456@2|Bacteria,1ZTIN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2428087_2	1123277.KB893217_gene4509	9.736e-53	191.0	COG2318@1|root,COG2318@2|Bacteria,4NNQA@976|Bacteroidetes,47Q00@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_2428087_5	523791.Kkor_0081	3.798e-12	77.0	2EGZQ@1|root,33ARU@2|Bacteria,1NR79@1224|Proteobacteria,1SKUB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2428087_4	1210884.HG799465_gene11440	6.34e-30	122.0	28WG9@1|root,2ZIGE@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WXD1_k127_2430623_0	1122223.KB890697_gene1095	2.524e-248	789.0	COG1012@1|root,COG1012@2|Bacteria,1WIGH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WXD1_k127_2430623_1	1128421.JAGA01000003_gene3727	6.061e-152	488.0	COG0274@1|root,COG0274@2|Bacteria	2|Bacteria	F	deoxyribose-phosphate aldolase activity	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WXD1_k127_2430623_6	861299.J421_3198	5.715e-55	202.0	COG2908@1|root,COG2908@2|Bacteria,1ZTNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
WXD1_k127_2430623_3	861299.J421_3197	2.102e-88	302.0	COG0796@1|root,COG0796@2|Bacteria,1ZUQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WXD1_k127_2430623_7	324602.Caur_2704	4.105e-44	173.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,375KA@32061|Chloroflexia	32061|Chloroflexia	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WXD1_k127_2430623_2	485913.Krac_11844	3.858e-124	415.0	COG0477@1|root,COG0477@2|Bacteria,2G5J9@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WXD1_k127_2430623_4	861299.J421_2752	2.784e-81	280.0	COG1760@1|root,COG1760@2|Bacteria,1ZT3U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
WXD1_k127_2430623_5	861299.J421_2751	4.632e-73	254.0	COG1760@1|root,COG1760@2|Bacteria,1ZTFS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Serine dehydratase beta chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
WXD1_k127_2430623_9	224324.aq_268	3.43e-19	96.0	COG1959@1|root,COG1959@2|Bacteria,2G59A@200783|Aquificae	200783|Aquificae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WXD1_k127_2430623_8	1128421.JAGA01000003_gene2823	2.569e-37	154.0	COG2606@1|root,COG2606@2|Bacteria,2NPZ1@2323|unclassified Bacteria	2|Bacteria	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WXD1_k127_2430745_5	861299.J421_0331	9.69e-44	163.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WXD1_k127_2430745_0	861299.J421_5896	2.675e-158	538.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_5896|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2430745_4	243365.CV_0096	1.457e-53	199.0	COG2273@1|root,COG2273@2|Bacteria,1RD4E@1224|Proteobacteria	1224|Proteobacteria	G	Hydrolase Family 16	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2430745_6	1144275.COCOR_07590	3.569e-39	153.0	COG3554@1|root,COG3554@2|Bacteria,1PV1V@1224|Proteobacteria,42XVB@68525|delta/epsilon subdivisions,2WXJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative glycolipid-binding	-	-	-	ko:K09957	-	-	-	-	ko00000	-	-	-	Glycolipid_bind
WXD1_k127_2430745_3	1499967.BAYZ01000158_gene443	6.122e-56	203.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
WXD1_k127_2430745_2	1356852.N008_17330	1.414e-61	216.0	COG1247@1|root,COG1247@2|Bacteria,4NNGH@976|Bacteroidetes,47Q9R@768503|Cytophagia	976|Bacteroidetes	M	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
WXD1_k127_2430745_1	379066.GAU_0228	8.264e-91	306.0	COG1680@1|root,COG1680@2|Bacteria,1ZUDN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_2466952_1	234267.Acid_5112	2.189e-25	105.0	COG0092@1|root,COG0092@2|Bacteria,3Y3ZN@57723|Acidobacteria	57723|Acidobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WXD1_k127_2466952_2	1000565.METUNv1_02538	0.0001407	48.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,2VTYE@28216|Betaproteobacteria,2KX1A@206389|Rhodocyclales	206389|Rhodocyclales	S	FixH family	-	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
WXD1_k127_2466952_0	296591.Bpro_4301	3.183e-215	677.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,4AB30@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
WXD1_k127_2505772_0	502025.Hoch_5309	4.428e-256	801.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
WXD1_k127_2505772_1	1121406.JAEX01000007_gene2385	9.137e-103	358.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,42U2G@68525|delta/epsilon subdivisions,2WQBG@28221|Deltaproteobacteria,2M8TG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Dihydroxyacetone kinase family	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
WXD1_k127_2505772_7	195250.CM001776_gene2386	8.142e-40	162.0	COG0251@1|root,COG0251@2|Bacteria,1G6TD@1117|Cyanobacteria,1H0H6@1129|Synechococcus	1117|Cyanobacteria	J	endoribonuclease L-PSP	tdcF	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Pentapeptide,Ribonuc_L-PSP
WXD1_k127_2505772_3	379066.GAU_1906	5.607e-90	310.0	COG2870@1|root,COG2870@2|Bacteria,1ZT0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
WXD1_k127_2505772_4	861299.J421_3477	7.736e-90	306.0	COG0767@1|root,COG0767@2|Bacteria,1ZUC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WXD1_k127_2505772_5	861299.J421_3476	2.662e-85	303.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	2|Bacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WXD1_k127_2505772_6	861299.J421_3475	2.747e-72	256.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	ttg2C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WXD1_k127_2505772_8	517722.AEUE01000010_gene626	1.182e-25	122.0	2C6BD@1|root,2ZZIY@2|Bacteria,1NWJY@1224|Proteobacteria,2USK5@28211|Alphaproteobacteria,2KAE8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2505772_2	861299.J421_3693	1.061e-96	326.0	COG1629@1|root,COG4771@2|Bacteria,1ZTDP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_2513469_1	861299.J421_4365	8.603e-93	316.0	2EY2H@1|root,33RBE@2|Bacteria,1ZTHK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2513469_0	861299.J421_4366	1.135e-112	372.0	COG1629@1|root,COG4771@2|Bacteria,1ZT7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WXD1_k127_2515711_0	861299.J421_6006	1.056e-107	374.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_2538528_2	1210884.HG799468_gene13551	4.389e-121	423.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_2538528_3	1123504.JQKD01000060_gene2920	1.338e-73	256.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2VNKF@28216|Betaproteobacteria,4AATQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WXD1_k127_2538528_4	1173029.JH980292_gene2635	3.542e-26	113.0	COG2703@1|root,COG2703@2|Bacteria,1G85F@1117|Cyanobacteria,1HCGI@1150|Oscillatoriales	1117|Cyanobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
WXD1_k127_2538528_0	518766.Rmar_2163	5.085e-218	687.0	COG2225@1|root,COG2225@2|Bacteria,4NF5H@976|Bacteroidetes,1FJVN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
WXD1_k127_2538528_1	526227.Mesil_1009	3.388e-202	638.0	COG2224@1|root,COG2224@2|Bacteria,1WI8Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
WXD1_k127_2548686_2	1123277.KB893206_gene3489	2.329e-125	409.0	COG2866@1|root,COG2866@2|Bacteria,4NIJ0@976|Bacteroidetes,47K8F@768503|Cytophagia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WXD1_k127_2548686_1	1128421.JAGA01000002_gene1962	1.124e-167	540.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2NQDQ@2323|unclassified Bacteria	2|Bacteria	P	Rhodanese Homology Domain	baeB	-	3.1.2.6,3.4.21.102	ko:K01069,ko:K03797	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000,ko01002	-	-	-	Lactamase_B,Rhodanese
WXD1_k127_2548686_8	517418.Ctha_1265	1.005e-25	113.0	COG0640@1|root,COG0640@2|Bacteria,1FE0W@1090|Chlorobi	1090|Chlorobi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
WXD1_k127_2548686_3	1499967.BAYZ01000118_gene3292	1.161e-123	424.0	COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
WXD1_k127_2548686_0	861299.J421_1048	5.818e-198	669.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WXD1_k127_2548686_4	1254432.SCE1572_09695	2.857e-68	249.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
WXD1_k127_2548686_7	1173263.Syn7502_00507	6.517e-28	120.0	2DC00@1|root,2ZC4V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2548686_6	861299.J421_2257	3.709e-28	124.0	COG1246@1|root,COG1246@2|Bacteria,1ZV2J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
WXD1_k127_2548686_5	1379270.AUXF01000001_gene2634	6.418e-32	137.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_2553984_1	379066.GAU_2504	1.396e-170	562.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2553984_0	926550.CLDAP_17390	2.355e-188	599.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,2G827@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
WXD1_k127_2556150_0	321327.CYA_2477	4.269e-119	398.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1GYE0@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WXD1_k127_2556150_1	313596.RB2501_07010	8.293e-43	172.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,4NFZR@976|Bacteroidetes,1HXXH@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidase m28	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PDZ_2,Peptidase_M28
WXD1_k127_2556150_2	1382305.AZUC01000014_gene2461	1.115e-39	165.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,4HA8B@91061|Bacilli	91061|Bacilli	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WXD1_k127_2556150_4	234267.Acid_2779	0.0002768	53.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg
WXD1_k127_2556150_3	861299.J421_4378	1.083e-34	152.0	COG3595@1|root,COG3595@2|Bacteria,1ZTQ0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WXD1_k127_2561295_1	1429916.X566_21020	1.174e-60	217.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
WXD1_k127_2561295_2	1536773.R70331_18065	1.223e-48	187.0	COG1247@1|root,COG1247@2|Bacteria,1V4AZ@1239|Firmicutes,4HGZ3@91061|Bacilli,26XQM@186822|Paenibacillaceae	91061|Bacilli	M	GNAT family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WXD1_k127_2561295_0	1379270.AUXF01000001_gene2323	6.373e-68	257.0	2EXVN@1|root,33R4S@2|Bacteria,1ZTD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2561295_4	926569.ANT_03020	8.333e-10	64.0	2BH31@1|root,32B3S@2|Bacteria,2G9T0@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WXD1_k127_2561295_3	909663.KI867150_gene2169	1.354e-35	141.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions,2WK7W@28221|Deltaproteobacteria,2MQ9G@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	MOFRL family	Glyctk	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
WXD1_k127_2620136_3	1379270.AUXF01000003_gene3738	3.002e-164	554.0	COG3127@1|root,COG3127@2|Bacteria,1ZT3A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WXD1_k127_2620136_8	379066.GAU_2113	1.051e-87	297.0	COG4181@1|root,COG4181@2|Bacteria,1ZUJS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_2620136_10	518766.Rmar_0540	1.082e-70	246.0	COG2755@1|root,COG2755@2|Bacteria,4NE58@976|Bacteroidetes,1FJCB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
WXD1_k127_2620136_18	1489678.RDMS_03610	1.254e-43	177.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091,ko:K07058	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WXD1_k127_2620136_14	1007103.AFHW01000025_gene338	3.753e-65	256.0	COG3361@1|root,COG3361@2|Bacteria,1UYZQ@1239|Firmicutes,4HEHN@91061|Bacilli,26Y28@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (COG2071)	yqjF	-	-	ko:K09166	-	-	-	-	ko00000	-	-	-	DUF2071
WXD1_k127_2620136_1	1219049.SP5_041_00140	6.428e-317	989.0	COG1222@1|root,COG1222@2|Bacteria,1QTV4@1224|Proteobacteria,2U0Q7@28211|Alphaproteobacteria,2K0N9@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
WXD1_k127_2620136_2	1379270.AUXF01000005_gene342	7.469e-179	578.0	COG2234@1|root,COG2234@2|Bacteria,1ZT2J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WXD1_k127_2620136_13	1047013.AQSP01000052_gene2599	1.286e-66	245.0	COG1668@1|root,COG1668@2|Bacteria,2NPCQ@2323|unclassified Bacteria	2|Bacteria	CP	ABC-2 family transporter protein	natB	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WXD1_k127_2620136_7	1047013.AQSP01000052_gene2600	8.652e-90	306.0	COG4152@1|root,COG4152@2|Bacteria,2NQE2@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WXD1_k127_2620136_24	1183438.GKIL_2692	2.725e-12	80.0	COG2105@1|root,COG2105@2|Bacteria	2|Bacteria	F	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
WXD1_k127_2620136_16	378806.STAUR_1528	1.404e-55	212.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
WXD1_k127_2620136_11	1173026.Glo7428_2219	2.652e-70	247.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2912 conserved	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
WXD1_k127_2620136_9	468059.AUHA01000004_gene2395	2.644e-80	284.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1IVD7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2620136_4	861299.J421_0488	9.94e-116	386.0	COG2223@1|root,COG2223@2|Bacteria,1ZT8I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WXD1_k127_2620136_21	1121374.KB891586_gene2509	7.634e-35	136.0	2C9TE@1|root,32RPW@2|Bacteria,1N8DZ@1224|Proteobacteria,1SF18@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	VL23_07270	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2620136_20	861299.J421_5670	3.843e-37	158.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5670|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2620136_19	861299.J421_1942	2.011e-42	164.0	COG1937@1|root,COG1937@2|Bacteria,1ZTZF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WXD1_k127_2620136_0	379066.GAU_2872	0.0	1285.0	COG0841@1|root,COG0841@2|Bacteria,1ZUFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WXD1_k127_2620136_12	1379270.AUXF01000001_gene2800	3.137e-68	236.0	COG0221@1|root,COG0221@2|Bacteria,1ZTH9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
WXD1_k127_2620136_22	1144275.COCOR_00143	7.546e-27	123.0	COG3795@1|root,COG3795@2|Bacteria,1NJ4J@1224|Proteobacteria	1224|Proteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
WXD1_k127_2620136_6	234267.Acid_2430	4.422e-91	316.0	COG4941@1|root,COG4941@2|Bacteria,3Y42G@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
WXD1_k127_2620136_23	234267.Acid_7191	5.729e-15	83.0	COG2823@1|root,COG2823@2|Bacteria,3Y8DF@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
WXD1_k127_2620136_5	429009.Adeg_0304	1.401e-98	331.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,42ENJ@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
WXD1_k127_2620136_15	1121456.ATVA01000015_gene2393	1.842e-61	231.0	28I4Y@1|root,2Z88D@2|Bacteria,1R95V@1224|Proteobacteria,42RX3@68525|delta/epsilon subdivisions,2WMGE@28221|Deltaproteobacteria,2MECJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2620136_17	379066.GAU_0745	1.107e-45	168.0	COG1249@1|root,COG1249@2|Bacteria,1ZT95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WXD1_k127_2633751_3	1166948.JPZL01000003_gene753	3.388e-25	109.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,1SCJZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
WXD1_k127_2633751_0	1501269.EW15_2118	7.688e-146	477.0	COG1304@1|root,COG1304@2|Bacteria,1G32Y@1117|Cyanobacteria,1MM3B@1212|Prochloraceae	1117|Cyanobacteria	C	L-lactate dehydrogenase	lldD	-	1.1.2.3,1.1.3.46	ko:K00101,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R06633	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
WXD1_k127_2633751_4	1499967.BAYZ01000145_gene6209	2.073e-11	72.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
WXD1_k127_2633751_1	861299.J421_2863	6.816e-88	296.0	2E3HM@1|root,32YG7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2633751_2	861299.J421_5904	8.031e-35	142.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
WXD1_k127_2634787_1	379066.GAU_0735	4.824e-93	315.0	COG1774@1|root,COG1774@2|Bacteria,1ZTE8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
WXD1_k127_2634787_0	1396141.BATP01000006_gene5499	7.013e-116	381.0	COG0825@1|root,COG0825@2|Bacteria,46SE1@74201|Verrucomicrobia,2IU0V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	ACCA
WXD1_k127_2634787_2	861299.J421_2656	1.428e-67	241.0	COG0587@1|root,COG0587@2|Bacteria,1ZT8N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helix-hairpin-helix motif	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
WXD1_k127_2663893_4	391625.PPSIR1_22466	2.43e-107	363.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,433Y1@68525|delta/epsilon subdivisions,2X41I@28221|Deltaproteobacteria,2YXYJ@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_2663893_2	867903.ThesuDRAFT_01937	6.886e-126	414.0	COG0235@1|root,COG0235@2|Bacteria,1UQ50@1239|Firmicutes	1239|Firmicutes	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
WXD1_k127_2663893_8	68170.KL590482_gene504	2.227e-33	136.0	COG3832@1|root,COG3832@2|Bacteria,2HS09@201174|Actinobacteria,4EBPC@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WXD1_k127_2663893_9	1280949.HAD_15142	4.836e-28	117.0	COG0640@1|root,COG0640@2|Bacteria,1N3ZI@1224|Proteobacteria,2UCYW@28211|Alphaproteobacteria,43YXF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
WXD1_k127_2663893_0	595460.RRSWK_03123	1.692e-259	833.0	COG1506@1|root,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WXD1_k127_2663893_10	1242864.D187_002220	6.637e-22	104.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2YXU5@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
WXD1_k127_2663893_3	861299.J421_0392	3.437e-122	406.0	COG1301@1|root,COG1301@2|Bacteria,1ZTDM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
WXD1_k127_2663893_7	861299.J421_0980	6.92e-53	189.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	MA20_04095	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt,YCII
WXD1_k127_2663893_5	518766.Rmar_0139	2.867e-82	280.0	COG0569@1|root,COG0569@2|Bacteria,4NGRQ@976|Bacteroidetes,1FJ8V@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WXD1_k127_2663893_1	518766.Rmar_0138	1.889e-164	531.0	COG0168@1|root,COG0168@2|Bacteria,4NF7R@976|Bacteroidetes,1FIT8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WXD1_k127_2663893_6	861299.J421_4451	8.455e-64	225.0	COG0590@1|root,COG0590@2|Bacteria	2|Bacteria	FJ	tRNA wobble adenosine to inosine editing	guaD	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
WXD1_k127_2663893_11	926566.Terro_4177	1.448e-18	93.0	29ZWG@1|root,30MXU@2|Bacteria,3Y5VK@57723|Acidobacteria,2JMXT@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_2666429_0	1379270.AUXF01000001_gene2301	2.759e-132	440.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1ZUF5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2666429_2	1379270.AUXF01000001_gene2300	1.856e-55	211.0	29X7K@1|root,30IWU@2|Bacteria,1ZUTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
WXD1_k127_2666429_1	1379270.AUXF01000001_gene2299	2.07e-118	387.0	COG0714@1|root,COG0714@2|Bacteria,1ZUSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WXD1_k127_2759_6	861299.J421_5993	2.31e-68	240.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WXD1_k127_2759_5	1379698.RBG1_1C00001G1666	9.977e-95	317.0	COG1136@1|root,COG1136@2|Bacteria,2NPA8@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_2759_4	861299.J421_5991	1.412e-97	341.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WXD1_k127_2759_3	861299.J421_5990	5.533e-114	385.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WXD1_k127_2759_8	861299.J421_1012	1.209e-49	197.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	-	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WXD1_k127_2759_9	1173020.Cha6605_3883	7.92e-35	139.0	2E6NS@1|root,33197@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2759_12	1121898.Q766_02945	1.56e-17	87.0	2AFKC@1|root,315MA@2|Bacteria,4PJSY@976|Bacteroidetes,1IAAY@117743|Flavobacteriia,2NZ4P@237|Flavobacterium	976|Bacteroidetes	S	Protein of unknown function (DUF3788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3788
WXD1_k127_2759_10	1223542.GM1_002_00120	1.486e-26	114.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4GEUR@85026|Gordoniaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
WXD1_k127_2759_0	84531.JMTZ01000036_gene450	3.359e-178	580.0	COG3525@1|root,COG3534@1|root,COG3525@2|Bacteria,COG3534@2|Bacteria,1MVDE@1224|Proteobacteria,1RMNI@1236|Gammaproteobacteria,1X9BH@135614|Xanthomonadales	135614|Xanthomonadales	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Glyco_hydro_20,Glyco_hydro_20b,PA14
WXD1_k127_2759_11	861299.J421_1152	5.942e-23	103.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WXD1_k127_2759_13	338969.Rfer_0021	3.616e-07	55.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,4AFBH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WXD1_k127_2759_2	1242864.D187_001429	3.731e-128	435.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1MXH7@1224|Proteobacteria,43AYG@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WXD1_k127_2759_7	383372.Rcas_3776	8.63e-59	217.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WXD1_k127_2759_1	309798.COPRO5265_1089	3.765e-166	533.0	COG2403@1|root,COG2403@2|Bacteria,1TPZD@1239|Firmicutes,24E2D@186801|Clostridia,42HSE@68295|Thermoanaerobacterales	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
WXD1_k127_2778515_10	1128421.JAGA01000003_gene3380	6.341e-38	162.0	COG3437@1|root,COG3437@2|Bacteria,2NPBP@2323|unclassified Bacteria	2|Bacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
WXD1_k127_2778515_12	1125973.JNLC01000016_gene2991	1.124e-23	117.0	COG2199@1|root,COG3706@2|Bacteria,1MXEP@1224|Proteobacteria,2U2ND@28211|Alphaproteobacteria,3JXHT@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WXD1_k127_2778515_9	518766.Rmar_0555	5.019e-43	163.0	COG3265@1|root,COG3265@2|Bacteria,4NQI4@976|Bacteroidetes	976|Bacteroidetes	G	TIGRFAM carbohydrate kinase, thermoresistant glucokinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	SKI
WXD1_k127_2778515_4	1122185.N792_08185	8.727e-132	426.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,1T1KM@1236|Gammaproteobacteria,1X4EG@135614|Xanthomonadales	135614|Xanthomonadales	G	6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WXD1_k127_2778515_8	42256.RradSPS_0960	7.62e-56	212.0	COG4288@1|root,COG4288@2|Bacteria,2IT13@201174|Actinobacteria,4CT9V@84995|Rubrobacteria	84995|Rubrobacteria	S	Anabaena sensory rhodopsin transducer	-	-	-	-	-	-	-	-	-	-	-	-	ASRT
WXD1_k127_2778515_6	42256.RradSPS_2372	2.576e-126	412.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4CQ61@84995|Rubrobacteria	84995|Rubrobacteria	C	F420-dependent oxidoreductase, G6PDH family	-	-	1.1.98.2	ko:K15510	-	-	-	-	ko00000,ko01000	-	-	-	Bac_luciferase
WXD1_k127_2778515_0	1185876.BN8_01295	1.201e-238	754.0	COG0366@1|root,COG0366@2|Bacteria,4NFE4@976|Bacteroidetes,47MCU@768503|Cytophagia	976|Bacteroidetes	G	Alpha-amylase domain	treS	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
WXD1_k127_2778515_2	945713.IALB_2034	9.952e-165	539.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
WXD1_k127_2778515_13	321327.CYA_0560	7.474e-10	66.0	COG1950@1|root,COG1950@2|Bacteria,1G835@1117|Cyanobacteria,1H1UR@1129|Synechococcus	1117|Cyanobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
WXD1_k127_2778515_11	1380390.JIAT01000010_gene3622	2.958e-27	119.0	2DPKA@1|root,332H3@2|Bacteria,2I2YH@201174|Actinobacteria,4CQ8H@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
WXD1_k127_2778515_3	700598.Niako_2072	1.379e-145	502.0	COG1680@1|root,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_2778515_1	649638.Trad_0630	1.088e-177	565.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_2778515_5	365046.Rta_06820	1.073e-129	420.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2VIAB@28216|Betaproteobacteria,4ABMF@80864|Comamonadaceae	28216|Betaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
WXD1_k127_280220_7	485913.Krac_7757	4.607e-89	299.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
WXD1_k127_280220_5	861299.J421_2808	1.109e-97	357.0	COG0492@1|root,COG0492@2|Bacteria,1ZSW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
WXD1_k127_280220_1	649638.Trad_1658	4.858e-132	451.0	COG2366@1|root,COG2366@2|Bacteria,1WJ3J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	peptidase S45, penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WXD1_k127_280220_3	861299.J421_3758	2.358e-114	381.0	COG0626@1|root,COG0626@2|Bacteria,1ZUSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
WXD1_k127_280220_0	671143.DAMO_2460	1.108e-227	731.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2NQFC@2323|unclassified Bacteria	2|Bacteria	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	mpg	-	1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8	ko:K00344,ko:K00966,ko:K01840,ko:K03431,ko:K15778,ko:K16881	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00361,M00362	R00885,R00959,R01057,R01818,R02060,R08639	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
WXD1_k127_280220_12	1231241.Mc24_08149	0.000122	53.0	2C0MY@1|root,2ZC2Z@2|Bacteria,2GD2U@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_280220_4	861299.J421_0110	1.253e-107	376.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WXD1_k127_280220_11	861299.J421_3756	5.258e-23	114.0	2EFCU@1|root,3395Q@2|Bacteria,1ZTVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_280220_9	861299.J421_3755	5.04e-78	273.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_280220_6	861299.J421_3754	4.754e-96	325.0	COG0524@1|root,COG0524@2|Bacteria,1ZTFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_280220_2	861299.J421_3753	1.962e-122	404.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WXD1_k127_280220_10	1232410.KI421414_gene2850	4.632e-34	148.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WXD1_k127_280220_8	518766.Rmar_2045	5.04e-81	273.0	COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,1FIPT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WXD1_k127_2803334_0	1379270.AUXF01000004_gene2932	0.0	1352.0	COG3459@1|root,COG3459@2|Bacteria,1ZTGS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
WXD1_k127_2803334_4	204669.Acid345_0617	2.297e-26	112.0	COG1695@1|root,COG1695@2|Bacteria,3Y4XK@57723|Acidobacteria,2JJR3@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WXD1_k127_2803334_1	861299.J421_5891	2.715e-125	435.0	COG0577@1|root,COG0577@2|Bacteria	861299.J421_5891|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2803334_3	1316936.K678_01186	4.286e-37	147.0	COG3428@1|root,COG3428@2|Bacteria,1N9PB@1224|Proteobacteria,2TUD0@28211|Alphaproteobacteria,2JU7A@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
WXD1_k127_2803334_5	1458427.BAWN01000009_gene622	1.456e-10	68.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,4AAGH@80864|Comamonadaceae	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
WXD1_k127_2803334_2	861299.J421_0160	3.495e-38	153.0	COG0840@1|root,COG0840@2|Bacteria,1ZUJ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
WXD1_k127_2837580_2	300852.55772493	1.509e-185	589.0	COG0466@1|root,COG0466@2|Bacteria,1WISX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WXD1_k127_2837580_3	479434.Sthe_0138	9.465e-38	162.0	COG1404@1|root,COG1404@2|Bacteria,2G7HM@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K14645,ko:K17734	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
WXD1_k127_2837580_1	861299.J421_1011	2.169e-263	833.0	COG3590@1|root,COG3590@2|Bacteria	2|Bacteria	O	peptidase	pepO	-	3.4.24.11,3.4.24.71	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
WXD1_k127_2837580_0	290397.Adeh_4307	0.0	1103.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
WXD1_k127_2837580_4	861299.J421_1020	8.583e-23	106.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
WXD1_k127_284066_0	1379270.AUXF01000002_gene1793	9.43e-239	758.0	COG0480@1|root,COG0480@2|Bacteria,1ZTFA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
WXD1_k127_284066_1	861299.J421_2336	4.162e-42	159.0	COG1993@1|root,COG1993@2|Bacteria	2|Bacteria	T	acr, cog1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
WXD1_k127_284066_2	1122221.JHVI01000013_gene2768	2.212e-31	130.0	COG0239@1|root,COG0239@2|Bacteria,1WK4E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
WXD1_k127_2851962_0	652103.Rpdx1_3378	1.123e-81	289.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,3JQWG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	MA20_17095	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_2853250_3	861299.J421_1072	1.747e-25	112.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
WXD1_k127_2853250_0	1121468.AUBR01000004_gene109	4.996e-131	433.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,42F49@68295|Thermoanaerobacterales	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WXD1_k127_2853250_6	1280674.AUJK01000003_gene1470	9.775e-11	63.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
WXD1_k127_2853250_4	861299.J421_1069	4.067e-18	91.0	COG0594@1|root,COG0594@2|Bacteria,1ZV89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WXD1_k127_2853250_2	546274.EIKCOROL_02381	2.565e-28	122.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,2KS03@206351|Neisseriales	206351|Neisseriales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WXD1_k127_2853250_1	861299.J421_1067	1.811e-99	345.0	COG0706@1|root,COG0706@2|Bacteria,1ZSKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WXD1_k127_2853250_5	504832.OCAR_5738	8.025e-14	82.0	COG1254@1|root,COG1254@2|Bacteria,1PU46@1224|Proteobacteria,2UF7Z@28211|Alphaproteobacteria,3K02B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WXD1_k127_2861292_3	861299.J421_3319	7.722e-71	246.0	COG0452@1|root,COG0452@2|Bacteria,1ZV19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WXD1_k127_2861292_4	243365.CV_3454	2.849e-55	202.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,2KR08@206351|Neisseriales	206351|Neisseriales	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WXD1_k127_2861292_2	1291050.JAGE01000001_gene1729	2.009e-131	433.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3WH8B@541000|Ruminococcaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WXD1_k127_2861292_0	861299.J421_3316	1.091e-167	538.0	COG1066@1|root,COG1066@2|Bacteria,1ZSYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase
WXD1_k127_2861292_7	861299.J421_3315	1.176e-41	164.0	COG1211@1|root,COG1211@2|Bacteria,1ZSTV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
WXD1_k127_2861292_5	861299.J421_3314	1.434e-42	164.0	COG0009@1|root,COG0009@2|Bacteria,1ZT3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
WXD1_k127_2861292_8	861299.J421_3313	4.347e-33	139.0	COG0394@1|root,COG0394@2|Bacteria,1ZTSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WXD1_k127_2861292_6	1128421.JAGA01000002_gene514	9.551e-42	166.0	COG0169@1|root,COG0169@2|Bacteria,2NPR3@2323|unclassified Bacteria	2|Bacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
WXD1_k127_2861292_9	861299.J421_3311	1.037e-26	119.0	COG1040@1|root,COG1040@2|Bacteria,1ZTS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WXD1_k127_2861292_1	861299.J421_3310	5.327e-144	463.0	COG0057@1|root,COG0057@2|Bacteria,1ZSTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WXD1_k127_2864541_2	483219.LILAB_10280	4.268e-134	465.0	COG0006@1|root,COG0006@2|Bacteria,1MVHD@1224|Proteobacteria	1224|Proteobacteria	E	Xaa-Pro aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
WXD1_k127_2864541_1	575540.Isop_2496	8.064e-173	560.0	COG3263@1|root,COG3263@2|Bacteria,2IY8F@203682|Planctomycetes	203682|Planctomycetes	P	COG3263 NhaP-type Na H and K H	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
WXD1_k127_2864541_5	1049564.TevJSym_af00510	9.273e-36	148.0	COG4122@1|root,COG4122@2|Bacteria,1RASF@1224|Proteobacteria,1S38Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
WXD1_k127_2864541_0	404589.Anae109_0989	1.515e-207	662.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
WXD1_k127_2864541_4	861299.J421_1888	1.301e-78	270.0	COG0745@1|root,COG0745@2|Bacteria,1ZUUR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WXD1_k127_2864541_3	861299.J421_1938	3.288e-87	306.0	COG0642@1|root,COG2205@2|Bacteria,1ZUG2@142182|Gemmatimonadetes	861299.J421_1938|-	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
WXD1_k127_2877308_5	1210884.HG799466_gene12816	8.784e-63	243.0	COG2203@1|root,COG3852@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_2877308_3	1485545.JQLW01000010_gene1564	1.094e-77	270.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria	1224|Proteobacteria	K	Esterase of the alpha-beta hydrolase superfamily	rssA	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WXD1_k127_2877308_4	518766.Rmar_2799	1.144e-69	251.0	COG3016@1|root,COG3016@2|Bacteria,4NEQ4@976|Bacteroidetes	976|Bacteroidetes	S	Iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
WXD1_k127_2877308_2	324602.Caur_2210	1.212e-128	420.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
WXD1_k127_2877308_0	331869.BAL199_02349	3.513e-163	542.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2U0XZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
WXD1_k127_2877308_1	861299.J421_6171	5.415e-152	491.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_6171|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2877308_6	861299.J421_3888	6.437e-06	49.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_3888|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2880943_1	861299.J421_3701	6.274e-175	556.0	COG0436@1|root,COG0436@2|Bacteria,1ZTCU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WXD1_k127_2880943_4	279714.FuraDRAFT_0055	1.827e-113	388.0	COG4564@1|root,COG5001@1|root,COG4564@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KQJ6@206351|Neisseriales	206351|Neisseriales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9,dCache_2
WXD1_k127_2880943_12	861299.J421_2996	2.435e-12	74.0	2FBQ3@1|root,343V1@2|Bacteria,1ZU1R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
WXD1_k127_2880943_0	861299.J421_2994	6.037e-320	1002.0	COG0525@1|root,COG0525@2|Bacteria,1ZSXQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WXD1_k127_2880943_10	1379270.AUXF01000005_gene588	4.856e-31	137.0	COG2372@1|root,COG2372@2|Bacteria,1ZTUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
WXD1_k127_2880943_3	1232410.KI421428_gene1195	1.048e-115	389.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,43S0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
WXD1_k127_2880943_8	941449.dsx2_2809	9.528e-48	178.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MBDI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	hydrolase, HAD-superfamily, subfamily IIIA	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
WXD1_k127_2880943_9	861299.J421_3606	8.034e-40	151.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
WXD1_k127_2880943_5	635013.TherJR_0217	2.599e-91	312.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,2608D@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
WXD1_k127_2880943_7	1304883.KI912532_gene1757	4.036e-48	181.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VHMC@28216|Betaproteobacteria,2KV0X@206389|Rhodocyclales	206389|Rhodocyclales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WXD1_k127_2880943_6	518766.Rmar_1872	3.195e-54	204.0	COG0299@1|root,COG0299@2|Bacteria,4NNZP@976|Bacteroidetes,1FITI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
WXD1_k127_2880943_2	1121013.P873_12175	1.699e-164	532.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1X3IH@135614|Xanthomonadales	135614|Xanthomonadales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WXD1_k127_2880943_11	861299.J421_4260	3.8e-29	122.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_2904620_0	477974.Daud_1685	1.893e-120	395.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,26192@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02615	GDP_Man_Dehyd
WXD1_k127_2904620_2	861299.J421_3520	9.949e-31	132.0	COG4464@1|root,COG4464@2|Bacteria,1ZTQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
WXD1_k127_2904620_1	247490.KSU1_C1600	3.043e-60	217.0	COG2148@1|root,COG2148@2|Bacteria,2IYWX@203682|Planctomycetes	203682|Planctomycetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WXD1_k127_2907129_2	1121468.AUBR01000027_gene2878	9.93e-23	101.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,42ETD@68295|Thermoanaerobacterales	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WXD1_k127_2907129_0	861299.J421_2575	2.339e-159	509.0	COG2255@1|root,COG2255@2|Bacteria,1ZT9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WXD1_k127_2907129_1	861299.J421_3994	1.11e-61	223.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	lpoB	GO:0000270,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0019899,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043085,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044093,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K07337,ko:K21008	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	LpoB
WXD1_k127_2908423_0	1089550.ATTH01000001_gene2545	6.562e-214	678.0	COG1115@1|root,COG1115@2|Bacteria,4NDX7@976|Bacteroidetes,1FIXE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
WXD1_k127_2908423_1	861299.J421_1944	9.322e-161	518.0	COG0659@1|root,COG0659@2|Bacteria,1ZTYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
WXD1_k127_2915512_1	861299.J421_0383	5.318e-40	154.0	COG2234@1|root,COG2234@2|Bacteria,1ZTDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WXD1_k127_2915512_3	584708.Apau_0184	8.136e-12	77.0	2A0DW@1|root,30NHH@2|Bacteria,3TCEU@508458|Synergistetes	508458|Synergistetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_2915512_2	663610.JQKO01000013_gene1806	6.191e-17	88.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,3N9Q5@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
WXD1_k127_2915512_0	215803.DB30_4063	3.419e-236	744.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria,2YZVC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WXD1_k127_3008828_0	1379270.AUXF01000004_gene3121	7.915e-133	450.0	COG4608@1|root,COG4608@2|Bacteria,1ZSTB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WXD1_k127_3008828_1	861299.J421_2680	4.99e-127	432.0	COG0444@1|root,COG0444@2|Bacteria,1ZSWI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WXD1_k127_3008828_3	243231.GSU1435	1.618e-85	298.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WXD1_k127_3008828_2	290512.Paes_0521	3.718e-106	353.0	COG0601@1|root,COG0601@2|Bacteria,1FDDB@1090|Chlorobi	1090|Chlorobi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WXD1_k127_3008828_4	338963.Pcar_1870	7.61e-78	283.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43S4Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
WXD1_k127_3008828_6	861299.J421_2684	9.093e-47	180.0	COG0095@1|root,COG0095@2|Bacteria,1ZTY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WXD1_k127_3008828_5	1121430.JMLG01000014_gene1926	1.216e-61	219.0	COG2220@1|root,COG2220@2|Bacteria,1TQR1@1239|Firmicutes,249X0@186801|Clostridia,260WU@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
WXD1_k127_3008828_7	379066.GAU_0764	4.814e-45	168.0	COG0509@1|root,COG0509@2|Bacteria,1ZTWD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WXD1_k127_3008828_8	1349820.M707_12315	0.0002651	49.0	COG5002@1|root,COG5002@2|Bacteria,2HGIV@201174|Actinobacteria,1WAGJ@1268|Micrococcaceae	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8
WXD1_k127_3035631_10	645465.ACUR01000203_gene601	2.425e-06	59.0	COG0167@1|root,COG0167@2|Bacteria,2HSAF@201174|Actinobacteria	201174|Actinobacteria	F	dihydroorotate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3035631_1	1089550.ATTH01000001_gene192	7.189e-157	514.0	COG0606@1|root,COG0606@2|Bacteria,4NE0G@976|Bacteroidetes,1FITT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WXD1_k127_3035631_8	1379270.AUXF01000001_gene1869	5.332e-10	72.0	COG1629@1|root,COG1629@2|Bacteria,1ZTI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WXD1_k127_3035631_0	861299.J421_1822	3.592e-205	683.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_3035631_3	861299.J421_1823	2.256e-81	289.0	28P8D@1|root,2ZC2C@2|Bacteria,1ZUEX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3035631_9	1379270.AUXF01000001_gene2088	5.97e-08	65.0	2DDI2@1|root,2ZI6I@2|Bacteria,1ZVAF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3035631_5	340.xcc-b100_2612	9.742e-49	181.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,1SBHQ@1236|Gammaproteobacteria,1X6JD@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
WXD1_k127_3035631_4	309801.trd_0620	8.187e-76	267.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
WXD1_k127_3035631_2	552398.HMPREF0866_01006	3.759e-86	299.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_3035631_6	290397.Adeh_3960	1.159e-34	140.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2YVZ3@29|Myxococcales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
WXD1_k127_3035631_7	1379270.AUXF01000005_gene479	1.672e-27	126.0	COG2204@1|root,COG2204@2|Bacteria,1ZT50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_3046453_6	1123392.AQWL01000003_gene487	7.781e-19	86.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,1KRQ9@119069|Hydrogenophilales	119069|Hydrogenophilales	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
WXD1_k127_3046453_1	1123392.AQWL01000003_gene488	5.733e-36	138.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria,1KRWM@119069|Hydrogenophilales	119069|Hydrogenophilales	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
WXD1_k127_3046453_0	1123392.AQWL01000003_gene489	1.702e-137	440.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,1KSEN@119069|Hydrogenophilales	119069|Hydrogenophilales	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WXD1_k127_3046453_5	543632.JOJL01000057_gene353	2.664e-28	129.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DAB5@85008|Micromonosporales	201174|Actinobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8
WXD1_k127_3046453_3	335283.Neut_1712	4.757e-35	147.0	COG3391@1|root,COG3391@2|Bacteria,1R78P@1224|Proteobacteria,2VJ7I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3046453_4	439235.Dalk_4363	2.607e-30	127.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WXD1_k127_3046453_2	439235.Dalk_4363	1.116e-35	145.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WXD1_k127_3067568_4	1121434.AULY01000007_gene1284	4.989e-05	52.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,42PHS@68525|delta/epsilon subdivisions,2X5NU@28221|Deltaproteobacteria,2MGTM@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	MlaD protein	pqiB	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
WXD1_k127_3067568_3	309807.SRU_0341	1.184e-30	131.0	COG3009@1|root,COG3009@2|Bacteria	2|Bacteria	Q	Protein conserved in bacteria	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
WXD1_k127_3067568_1	349521.HCH_01685	5.605e-93	317.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,1RN5Z@1236|Gammaproteobacteria,1XI47@135619|Oceanospirillales	135619|Oceanospirillales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WXD1_k127_3067568_2	518766.Rmar_0728	2.787e-62	222.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1FJ6B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
WXD1_k127_3067568_0	234267.Acid_3259	2.173e-212	670.0	COG1297@1|root,COG1297@2|Bacteria,3Y3SD@57723|Acidobacteria	57723|Acidobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
WXD1_k127_3080673_4	42256.RradSPS_2777	3.806e-10	68.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
WXD1_k127_3080673_3	861299.J421_2851	1.706e-34	153.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	BTAD
WXD1_k127_3080673_0	929556.Solca_3818	1.836e-60	235.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,4NFW7@976|Bacteroidetes,1IR3J@117747|Sphingobacteriia	976|Bacteroidetes	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_2,TPR_8
WXD1_k127_3080673_2	204669.Acid345_4455	1.043e-34	139.0	COG2318@1|root,COG2318@2|Bacteria,3Y82J@57723|Acidobacteria,2JN4W@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_3080673_5	929713.NIASO_00450	1.183e-07	62.0	293ZH@1|root,2ZREG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3080673_1	929713.NIASO_00445	9.095e-45	179.0	2BXDT@1|root,2ZKKS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3090613_0	1125863.JAFN01000001_gene3028	1.416e-241	769.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WXD1_k127_3090613_2	767817.Desgi_2325	6.618e-05	55.0	COG0823@1|root,COG0823@2|Bacteria,1VZ57@1239|Firmicutes,2543M@186801|Clostridia,265XM@186807|Peptococcaceae	186801|Clostridia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3090613_1	1379270.AUXF01000006_gene42	2.564e-159	512.0	COG0468@1|root,COG0468@2|Bacteria,1ZT78@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WXD1_k127_3090613_3	861299.J421_2476	0.0002592	49.0	2AETH@1|root,314QH@2|Bacteria,1ZU7R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3099629_1	861299.J421_2748	4.185e-163	517.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WXD1_k127_3099629_2	379066.GAU_2951	4.233e-07	61.0	COG4206@1|root,COG4206@2|Bacteria,1ZU97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_3099629_0	588932.JHOF01000026_gene358	2.154e-259	824.0	COG1506@1|root,COG1506@2|Bacteria,1N75C@1224|Proteobacteria,2TVNG@28211|Alphaproteobacteria,2KHPF@204458|Caulobacterales	204458|Caulobacterales	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WXD1_k127_3118641_7	1049564.TevJSym_at00550	5.467e-49	178.0	COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1J69D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S protein	ycbX	GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754	-	ko:K07140	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1
WXD1_k127_3118641_17	365528.KB891170_gene5146	4.869e-08	64.0	COG0515@1|root,COG3386@1|root,COG0515@2|Bacteria,COG3386@2|Bacteria,2GKFY@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WXD1_k127_3118641_16	1125863.JAFN01000001_gene851	3.902e-08	57.0	2EM0B@1|root,33EPU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3118641_11	861299.J421_6107	6.934e-35	141.0	2CIH2@1|root,2ZTG0@2|Bacteria	2|Bacteria	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
WXD1_k127_3118641_0	861299.J421_3032	7.851e-307	957.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZTF0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WXD1_k127_3118641_8	358681.BBR47_37570	1.332e-47	176.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_3118641_2	404589.Anae109_4301	5.292e-181	579.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,430DD@68525|delta/epsilon subdivisions,2WVKB@28221|Deltaproteobacteria,2YUBR@29|Myxococcales	28221|Deltaproteobacteria	F	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	ligB	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
WXD1_k127_3118641_9	1437425.CSEC_2070	2.145e-42	162.0	COG0662@1|root,COG0662@2|Bacteria,2JGB2@204428|Chlamydiae	204428|Chlamydiae	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WXD1_k127_3118641_19	58344.JOEL01000041_gene3551	3.499e-06	59.0	COG1506@1|root,COG1506@2|Bacteria,2GMMM@201174|Actinobacteria	201174|Actinobacteria	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,PD40,Peptidase_S9
WXD1_k127_3118641_10	324925.Ppha_2445	6.267e-40	164.0	COG0702@1|root,COG0702@2|Bacteria,1FEYW@1090|Chlorobi	1090|Chlorobi	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WXD1_k127_3118641_6	518766.Rmar_2430	7.031e-66	235.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes	976|Bacteroidetes	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
WXD1_k127_3118641_4	861299.J421_5904	1.177e-146	501.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
WXD1_k127_3118641_12	1121028.ARQE01000003_gene659	1.34e-25	122.0	2CFNJ@1|root,32S24@2|Bacteria,1N1K9@1224|Proteobacteria,2UDHS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3618)	ndiB	-	-	-	-	-	-	-	-	-	-	-	DUF3618
WXD1_k127_3118641_20	35754.JNYJ01000008_gene3190	0.0009972	48.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4DEUJ@85008|Micromonosporales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
WXD1_k127_3118641_15	690850.Desaf_0878	4.966e-12	77.0	29Y2N@1|root,30JVK@2|Bacteria,1Q4DJ@1224|Proteobacteria,432TH@68525|delta/epsilon subdivisions,2WXSN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3118641_3	861299.J421_0763	4.007e-153	498.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_3118641_1	861299.J421_0764	2.861e-187	600.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	2|Bacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_3118641_14	1396141.BATP01000004_gene5888	5.78e-13	75.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3118641_5	1191523.MROS_0148	1.576e-83	294.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
WXD1_k127_3120003_9	861299.J421_2851	7.87e-47	187.0	COG0515@1|root,COG3629@1|root,COG0515@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	BTAD
WXD1_k127_3120003_11	861299.J421_2922	6.966e-32	128.0	COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WXD1_k127_3120003_6	880073.Calab_2288	1.288e-60	213.0	COG0102@1|root,COG0102@2|Bacteria,2NPCI@2323|unclassified Bacteria	2|Bacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WXD1_k127_3120003_10	861299.J421_3413	1.743e-44	164.0	COG0103@1|root,COG0103@2|Bacteria,1ZTM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WXD1_k127_3120003_2	1379270.AUXF01000006_gene119	3.822e-95	322.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WXD1_k127_3120003_5	944479.JQLX01000015_gene80	1.645e-67	235.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2M6IY@213113|Desulfurellales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WXD1_k127_3120003_1	861299.J421_3410	1.072e-95	321.0	COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WXD1_k127_3120003_8	1125863.JAFN01000001_gene967	1.175e-58	209.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WXD1_k127_3120003_3	861299.J421_3408	2.662e-90	303.0	COG0020@1|root,COG0020@2|Bacteria,1ZSNJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WXD1_k127_3120003_7	379066.GAU_1771	1.805e-60	219.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WXD1_k127_3120003_0	861299.J421_3406	2.303e-126	417.0	COG0743@1|root,COG0743@2|Bacteria,1ZTFR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
WXD1_k127_3120003_4	1123368.AUIS01000001_gene2043	5.295e-78	280.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,2NC9P@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
WXD1_k127_3120003_12	1429916.X566_22865	3.518e-17	96.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2TQK5@28211|Alphaproteobacteria,3JSD0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	MA20_01050	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Fer4_7,NADH_4Fe-4S,Pyr_redox_2,Pyr_redox_3
WXD1_k127_3130572_0	379066.GAU_3101	2.798e-139	450.0	COG0714@1|root,COG0714@2|Bacteria,1ZUSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WXD1_k127_3130572_1	1379270.AUXF01000001_gene2298	1.356e-96	324.0	COG1721@1|root,COG1721@2|Bacteria,1ZUD5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WXD1_k127_3130572_2	379066.GAU_3103	4.209e-48	194.0	COG1572@1|root,COG2304@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,1ZUB7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
WXD1_k127_3138838_11	1202532.FF52_22079	2.496e-05	49.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria,4NJK3@976|Bacteroidetes,1I16K@117743|Flavobacteriia,2NV08@237|Flavobacterium	976|Bacteroidetes	E	Pregnancy-associated plasma protein-A	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M43,fn3
WXD1_k127_3138838_7	1443665.JACA01000015_gene4371	1.14e-17	85.0	COG1404@1|root,COG3227@1|root,COG3291@1|root,COG3975@1|root,COG1404@2|Bacteria,COG3227@2|Bacteria,COG3291@2|Bacteria,COG3975@2|Bacteria,4NHDH@976|Bacteroidetes,1IF30@117743|Flavobacteriia,2YIBS@290174|Aquimarina	976|Bacteroidetes	O	Peptidase family M9 N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_M9,Peptidase_M9_N
WXD1_k127_3138838_8	1379270.AUXF01000006_gene269	3.071e-14	81.0	2DWX3@1|root,342B9@2|Bacteria,1ZTXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
WXD1_k127_3138838_12	1173029.JH980292_gene824	0.0002329	53.0	COG1934@1|root,COG1934@2|Bacteria,1G6KC@1117|Cyanobacteria,1HBSV@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM OstA-like protein	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
WXD1_k127_3138838_1	861299.J421_3251	6.582e-119	394.0	COG1137@1|root,COG1137@2|Bacteria,1ZT4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
WXD1_k127_3138838_0	861299.J421_3250	5.293e-221	698.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WXD1_k127_3138838_4	1379698.RBG1_1C00001G1315	4.048e-72	255.0	COG0463@1|root,COG0463@2|Bacteria,2NP2G@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WXD1_k127_3138838_2	1121422.AUMW01000012_gene2938	7.298e-112	373.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,26040@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
WXD1_k127_3138838_6	378806.STAUR_0613	2.621e-31	140.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2Z144@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_3138838_3	861299.J421_3246	2.043e-90	327.0	COG5617@1|root,COG5617@2|Bacteria,1ZUMG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WXD1_k127_3138838_10	1380393.JHVP01000001_gene2530	1.68e-11	76.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4EU2T@85013|Frankiales	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WXD1_k127_3138838_9	266940.Krad_3864	2.241e-12	79.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
WXD1_k127_3138838_5	1379270.AUXF01000006_gene276	7.515e-53	204.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WXD1_k127_3155618_9	861299.J421_0234	1.278e-12	79.0	2B23P@1|root,342TN@2|Bacteria,1ZUP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3155618_0	861299.J421_2834	3.104e-170	553.0	COG1132@1|root,COG1132@2|Bacteria,1ZT5Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
WXD1_k127_3155618_8	983920.Y88_0205	9.725e-20	94.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,2K0MT@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WXD1_k127_3155618_4	861299.J421_2831	1.029e-64	229.0	COG0785@1|root,COG0785@2|Bacteria,1ZTJC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WXD1_k127_3155618_1	1232410.KI421421_gene3566	1.61e-111	382.0	COG1524@1|root,COG1524@2|Bacteria,1QX9K@1224|Proteobacteria	1224|Proteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WXD1_k127_3155618_3	331113.SNE_A06120	9.432e-72	253.0	COG0010@1|root,COG0010@2|Bacteria,2JG0D@204428|Chlamydiae	204428|Chlamydiae	E	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide	speB1	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WXD1_k127_3155618_7	861299.J421_2828	4.627e-36	142.0	COG0735@1|root,COG0735@2|Bacteria,1ZTN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WXD1_k127_3155618_2	861299.J421_3916	9.083e-80	288.0	COG0618@1|root,COG0618@2|Bacteria,1ZSS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WXD1_k127_3155618_6	525904.Tter_0400	8.595e-39	158.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
WXD1_k127_3155618_5	1379270.AUXF01000004_gene3113	5.455e-42	169.0	COG0237@1|root,COG0237@2|Bacteria,1ZTM2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WXD1_k127_3155618_10	765911.Thivi_0119	4.764e-05	52.0	2FIT9@1|root,34AIT@2|Bacteria,1P2BG@1224|Proteobacteria	1224|Proteobacteria	S	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSG
WXD1_k127_3155618_11	1379270.AUXF01000001_gene2453	0.0001134	46.0	2FKCY@1|root,34C0C@2|Bacteria,1ZU3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_315881_2	1502852.FG94_02033	6.616e-89	309.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,473PD@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Glycolate oxidase, iron-sulfur subunit	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
WXD1_k127_315881_0	926562.Oweho_1935	2.299e-212	685.0	COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,1HYR7@117743|Flavobacteriia,2PA7N@246874|Cryomorphaceae	976|Bacteroidetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N
WXD1_k127_315881_7	234267.Acid_5182	1.21e-16	84.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
WXD1_k127_315881_6	1382305.AZUC01000047_gene935	3.996e-28	119.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,26FH1@186818|Planococcaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WXD1_k127_315881_4	357808.RoseRS_3755	7.985e-53	198.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi,375GZ@32061|Chloroflexia	32061|Chloroflexia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
WXD1_k127_315881_3	861299.J421_3191	2.434e-76	268.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WXD1_k127_315881_8	1411123.JQNH01000001_gene2475	3.975e-07	53.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WXD1_k127_315881_5	861299.J421_3402	9.749e-31	123.0	COG0184@1|root,COG0184@2|Bacteria,1ZU0C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WXD1_k127_315881_1	379066.GAU_1764	6.877e-138	449.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WXD1_k127_3175827_3	644966.Tmar_2275	3.522e-68	238.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3WCG7@538999|Clostridiales incertae sedis	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
WXD1_k127_3175827_1	1379270.AUXF01000004_gene3010	5.783e-93	312.0	COG0024@1|root,COG0024@2|Bacteria,1ZTC1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WXD1_k127_3175827_8	379066.GAU_1977	8.379e-15	74.0	COG0257@1|root,COG0257@2|Bacteria,1ZVAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WXD1_k127_3175827_5	525903.Taci_1158	9.412e-50	180.0	COG0099@1|root,COG0099@2|Bacteria,3TAYV@508458|Synergistetes	508458|Synergistetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WXD1_k127_3175827_4	379066.GAU_1975	1.696e-58	205.0	COG0100@1|root,COG0100@2|Bacteria,1ZTMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WXD1_k127_3175827_2	861299.J421_3577	3.967e-92	307.0	COG0522@1|root,COG0522@2|Bacteria,1ZTGJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WXD1_k127_3175827_0	861299.J421_3576	2.856e-115	381.0	COG0202@1|root,COG0202@2|Bacteria,1ZTEV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WXD1_k127_3175827_6	861299.J421_3575	6.097e-35	136.0	COG0203@1|root,COG0203@2|Bacteria,1ZTPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WXD1_k127_3175827_7	796940.HMPREF9628_00853	7.607e-17	81.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WXD1_k127_3185795_2	32042.PstZobell_08937	2.356e-28	116.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,1T1YP@1236|Gammaproteobacteria,1Z1XK@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	T	COG0642 Signal transduction histidine kinase	torS	-	2.7.13.3	ko:K07647,ko:K07678,ko:K20974	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00455,M00475,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,CHASE3,DUF2222,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_3185795_0	379066.GAU_3745	7.187e-220	697.0	COG2274@1|root,COG2274@2|Bacteria,1ZSX6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
WXD1_k127_3185795_1	313596.RB2501_00846	3.224e-66	231.0	COG1680@1|root,COG1680@2|Bacteria,4NGZR@976|Bacteroidetes,1HXEI@117743|Flavobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_3207051_7	1192034.CAP_2673	1.346e-15	87.0	COG0249@1|root,COG0249@2|Bacteria,1N9K4@1224|Proteobacteria,42ZN5@68525|delta/epsilon subdivisions,2WUW7@28221|Deltaproteobacteria,2YTSE@29|Myxococcales	28221|Deltaproteobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
WXD1_k127_3207051_1	338966.Ppro_1962	1.481e-88	304.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,42M82@68525|delta/epsilon subdivisions,2WKGK@28221|Deltaproteobacteria,43U0E@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
WXD1_k127_3207051_0	1210884.HG799466_gene13015	1.813e-97	327.0	COG0053@1|root,COG0053@2|Bacteria,2IY05@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WXD1_k127_3207051_2	880073.Calab_0191	2.599e-57	210.0	2AMSR@1|root,31CP7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3207051_3	661478.OP10G_0939	6.218e-55	200.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114	1.13.11.49	ko:K09162	-	-	-	-	ko00000,ko01000	-	-	-	Chlor_dismutase
WXD1_k127_3207051_4	1254432.SCE1572_28200	3.865e-34	149.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2WPW2@28221|Deltaproteobacteria,2YY5H@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_3207051_5	765420.OSCT_0869	1.614e-31	137.0	COG0438@1|root,COG0438@2|Bacteria,2GA72@200795|Chloroflexi,376YG@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_32082_8	1121920.AUAU01000014_gene2832	1.533e-14	85.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,LysM
WXD1_k127_32082_2	335543.Sfum_3057	6.427e-134	435.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,2MQY0@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
WXD1_k127_32082_5	1094508.Tsac_2621	1.914e-29	132.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
WXD1_k127_32082_6	877420.ATVW01000049_gene999	4.735e-28	128.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,27IG5@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
WXD1_k127_32082_7	861299.J421_3560	4.866e-27	117.0	COG0802@1|root,COG0802@2|Bacteria,1ZTY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	2.7.1.221	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	TsaE
WXD1_k127_32082_0	379066.GAU_1953	1.684e-295	929.0	COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WXD1_k127_32082_1	1379270.AUXF01000006_gene5	9.078e-279	875.0	COG0317@1|root,COG0317@2|Bacteria,1ZT5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WXD1_k127_32082_4	861299.J421_3564	2.191e-72	252.0	COG2003@1|root,COG2003@2|Bacteria,1ZTFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WXD1_k127_32082_3	379066.GAU_1961	5.64e-106	358.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WXD1_k127_32082_9	1196031.ALEG01000053_gene558	1.36e-09	59.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli,1ZAXF@1386|Bacillus	91061|Bacilli	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WXD1_k127_3219395_11	861299.J421_1627	1.054e-59	216.0	COG1720@1|root,COG1720@2|Bacteria	2|Bacteria	S	tRNA m6t6A37 methyltransferase activity	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
WXD1_k127_3219395_9	1121104.AQXH01000001_gene1705	1.119e-62	225.0	COG3544@1|root,COG3544@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
WXD1_k127_3219395_0	861299.J421_4121	1.498e-278	883.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WXD1_k127_3219395_16	1144275.COCOR_03296	2.267e-22	111.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,4346C@68525|delta/epsilon subdivisions,2X20P@28221|Deltaproteobacteria,2Z2GY@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin reductase like domain	-	-	1.5.1.36	ko:K00484,ko:K16048	ko00350,ko00740,ko00984,ko01100,ko01120,ko01220,map00350,map00740,map00984,map01100,map01120,map01220	-	R02698,R03299,R05705,R09748,R09750,R09819	RC00046,RC00126,RC00236	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct,Methyltransf_11
WXD1_k127_3219395_8	103690.17129716	1.537e-120	402.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria,1HKZ8@1161|Nostocales	1117|Cyanobacteria	EGP	major facilitator superfamily MFS_1	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
WXD1_k127_3219395_3	1195246.AGRI_04512	9.319e-192	613.0	COG0477@1|root,COG2814@2|Bacteria,1R5AK@1224|Proteobacteria,1SI9U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WXD1_k127_3219395_4	1121930.AQXG01000002_gene2285	2.39e-168	541.0	COG0471@1|root,COG0471@2|Bacteria,4PIFM@976|Bacteroidetes,1ITUY@117747|Sphingobacteriia	976|Bacteroidetes	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319	-	-	-	-	ko00000	2.A.47	-	-	Na_sulph_symp
WXD1_k127_3219395_15	604331.AUHY01000030_gene978	3.062e-24	113.0	COG0797@1|root,COG0797@2|Bacteria,1WJRE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,LysM
WXD1_k127_3219395_6	1120971.AUCA01000001_gene1727	2.12e-152	495.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,4HA4Q@91061|Bacilli,278WZ@186823|Alicyclobacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WXD1_k127_3219395_17	1266925.JHVX01000002_gene740	3.894e-05	55.0	2AH9J@1|root,317JQ@2|Bacteria,1PYWZ@1224|Proteobacteria,2WE1A@28216|Betaproteobacteria,374AC@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Bor protein	-	-	-	-	-	-	-	-	-	-	-	-	Lambda_Bor
WXD1_k127_3219395_10	1144275.COCOR_07375	1.371e-62	235.0	COG0277@1|root,COG0277@2|Bacteria,1RKIM@1224|Proteobacteria	1224|Proteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
WXD1_k127_3219395_12	1123393.KB891328_gene523	8.644e-54	196.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,2VMVW@28216|Betaproteobacteria,1KRXJ@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
WXD1_k127_3219395_1	861299.J421_0695	4.753e-236	755.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_3219395_14	1122222.AXWR01000037_gene278	1.967e-30	139.0	COG0412@1|root,COG0412@2|Bacteria,1WM5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WXD1_k127_3219395_7	861299.J421_2750	1.512e-135	456.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,SdrD_B,TIG,fn3_3
WXD1_k127_3219395_13	1379270.AUXF01000004_gene3009	9.621e-46	177.0	COG2318@1|root,COG2318@2|Bacteria,1ZU3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_3219395_18	314278.NB231_08247	0.0001355	54.0	COG0457@1|root,COG0457@2|Bacteria,1RIHH@1224|Proteobacteria,1S8T0@1236|Gammaproteobacteria,1WZT6@135613|Chromatiales	135613|Chromatiales	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
WXD1_k127_3219395_5	379066.GAU_3182	4.85e-160	511.0	COG1902@1|root,COG1902@2|Bacteria,1ZTAW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
WXD1_k127_3219395_2	1179773.BN6_32200	1.57e-197	626.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4DZA4@85010|Pseudonocardiales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WXD1_k127_323624_5	926554.KI912633_gene4061	2.372e-39	149.0	298NJ@1|root,2ZVT4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_323624_7	929556.Solca_2617	4.223e-35	140.0	COG1388@1|root,COG1388@2|Bacteria,4NNEY@976|Bacteroidetes,1IV0U@117747|Sphingobacteriia	976|Bacteroidetes	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,LysM
WXD1_k127_323624_1	1221522.B723_20230	9.193e-63	224.0	COG2173@1|root,COG3786@1|root,COG2173@2|Bacteria,COG3786@2|Bacteria,1RENK@1224|Proteobacteria,1S3SJ@1236|Gammaproteobacteria,1YR3J@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009046,GO:0009605,GO:0009991,GO:0016787,GO:0019538,GO:0031667,GO:0042594,GO:0043170,GO:0044238,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
WXD1_k127_323624_3	84531.JMTZ01000168_gene741	7.126e-60	210.0	COG3189@1|root,COG3189@2|Bacteria,1RHYB@1224|Proteobacteria,1S9MZ@1236|Gammaproteobacteria,1X6ZP@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
WXD1_k127_323624_6	1121920.AUAU01000026_gene1478	2.188e-36	147.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_323624_4	1123368.AUIS01000033_gene1379	1.9e-48	188.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,1SBDJ@1236|Gammaproteobacteria,2NDBI@225057|Acidithiobacillales	225057|Acidithiobacillales	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
WXD1_k127_323624_0	1458275.AZ34_05245	1.524e-71	254.0	COG0262@1|root,COG0262@2|Bacteria,1R6X0@1224|Proteobacteria,2VI26@28216|Betaproteobacteria,4AB69@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
WXD1_k127_323624_2	1183438.GKIL_1240	3.039e-60	222.0	COG1335@1|root,COG1335@2|Bacteria,1GAHK@1117|Cyanobacteria	1117|Cyanobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
WXD1_k127_323624_8	1210884.HG799465_gene11440	3.127e-12	77.0	28WG9@1|root,2ZIGE@2|Bacteria	2|Bacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WXD1_k127_3242165_0	1333998.M2A_2719	1.663e-114	382.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,4BRV7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	PFAM Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WXD1_k127_3242165_6	861299.J421_2716	5.717e-28	119.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2716|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3242165_2	1173022.Cri9333_4627	1.016e-93	317.0	COG1366@1|root,COG1366@2|Bacteria,1G1ZX@1117|Cyanobacteria,1H9T7@1150|Oscillatoriales	1117|Cyanobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	-	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	Protoglobin,RsbRD_N,STAS
WXD1_k127_3242165_5	204669.Acid345_2415	9.78e-45	179.0	COG1366@1|root,COG1366@2|Bacteria,3Y4YT@57723|Acidobacteria,2JJGC@204432|Acidobacteriia	204432|Acidobacteriia	T	transporter antisigma-factor antagonist STAS	-	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	-
WXD1_k127_3242165_4	937777.Deipe_0534	3.982e-49	179.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	rsbT	-	2.7.11.1	ko:K04757,ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
WXD1_k127_3242165_3	179408.Osc7112_4130	3.439e-75	269.0	COG2172@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,1G02S@1117|Cyanobacteria,1H8SM@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE
WXD1_k127_3242165_1	335659.S23_24520	3.136e-114	391.0	COG2172@1|root,COG4251@1|root,COG2172@2|Bacteria,COG4251@2|Bacteria,1QUZZ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WXD1_k127_3255524_1	518766.Rmar_1354	6.576e-61	236.0	COG3001@1|root,COG3001@2|Bacteria,4NEQY@976|Bacteroidetes,1FJ00@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
WXD1_k127_3255524_2	502025.Hoch_3589	3.492e-42	163.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42RY9@68525|delta/epsilon subdivisions,2WW61@28221|Deltaproteobacteria,2Z2RX@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WXD1_k127_3255524_4	1379270.AUXF01000004_gene3063	4.198e-28	125.0	COG3204@1|root,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	5_nucleotid_C,Big_5,Exo_endo_phos,LTD,SdiA-regulated,VPEP
WXD1_k127_3255524_0	861299.J421_4088	2.253e-244	781.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,GDE_C,SLH
WXD1_k127_3255524_5	861299.J421_3799	7.882e-27	125.0	COG0741@1|root,COG0741@2|Bacteria,1ZTV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WXD1_k127_3255524_3	234267.Acid_6511	3.241e-40	169.0	COG2234@1|root,COG2234@2|Bacteria,3Y3S9@57723|Acidobacteria	57723|Acidobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WXD1_k127_3258032_0	379066.GAU_0139	7.856e-236	752.0	COG0079@1|root,COG0141@1|root,COG0079@2|Bacteria,COG0141@2|Bacteria,1ZT8V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
WXD1_k127_3258032_5	861299.J421_1271	1.764e-62	221.0	COG0118@1|root,COG0118@2|Bacteria,1ZTIJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WXD1_k127_3258032_6	1379270.AUXF01000002_gene1405	4.408e-62	229.0	COG0106@1|root,COG0106@2|Bacteria,1ZSZJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Histidine biosynthesis protein	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WXD1_k127_3258032_7	379066.GAU_0136	7.855e-60	226.0	COG0131@1|root,COG0131@2|Bacteria,1ZTHU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
WXD1_k127_3258032_2	1144275.COCOR_03712	2.369e-99	333.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2YUN8@29|Myxococcales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K01663,ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,His_biosynth
WXD1_k127_3258032_3	383372.Rcas_0945	4.945e-83	286.0	COG0483@1|root,COG0483@2|Bacteria,2G7NN@200795|Chloroflexi,375HQ@32061|Chloroflexia	32061|Chloroflexia	G	PFAM inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
WXD1_k127_3258032_10	584708.Apau_2183	8.845e-41	174.0	COG0139@1|root,COG0139@2|Bacteria,3TASS@508458|Synergistetes	508458|Synergistetes	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
WXD1_k127_3258032_13	414996.IL38_18805	8.97e-24	105.0	COG2261@1|root,COG2261@2|Bacteria,2HPF1@201174|Actinobacteria,409F8@622450|Actinopolysporales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WXD1_k127_3258032_9	401526.TcarDRAFT_1119	4.59e-45	184.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H2VB@909932|Negativicutes	909932|Negativicutes	NT	SMART chemotaxis sensory transducer, histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
WXD1_k127_3258032_11	502025.Hoch_5250	2.297e-39	156.0	COG4758@1|root,COG4758@2|Bacteria,1RANH@1224|Proteobacteria	1224|Proteobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
WXD1_k127_3258032_1	379066.GAU_2174	1.51e-180	589.0	COG1132@1|root,COG1132@2|Bacteria,1ZSZC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
WXD1_k127_3258032_12	861299.J421_2638	2.103e-35	139.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2638|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3258032_4	861299.J421_2639	5.667e-75	275.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	2.6.1.85	ko:K13950,ko:K21025	ko00790,ko02025,map00790,map02025	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF
WXD1_k127_3258032_8	861299.J421_2640	8.252e-52	205.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WXD1_k127_3277519_1	1267535.KB906767_gene629	1.228e-151	488.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria,2JHW9@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_3277519_4	1124780.ANNU01000073_gene708	6.471e-72	251.0	COG0170@1|root,COG0170@2|Bacteria,4P0IJ@976|Bacteroidetes,47TKF@768503|Cytophagia	976|Bacteroidetes	I	dolichyl monophosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3277519_0	215803.DB30_7235	7.356e-158	527.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria,433ZM@68525|delta/epsilon subdivisions,2X48T@28221|Deltaproteobacteria,2YYI5@29|Myxococcales	1224|Proteobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_3277519_3	1267535.KB906767_gene632	1.478e-107	354.0	COG1136@1|root,COG1136@2|Bacteria,3Y2J0@57723|Acidobacteria,2JIKD@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_3277519_2	861299.J421_0290	3.67e-113	379.0	COG0845@1|root,COG0845@2|Bacteria,1ZUP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
WXD1_k127_3277519_6	1038869.AXAN01000116_gene3483	4.305e-09	70.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,2VHU4@28216|Betaproteobacteria,1K43T@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	cyaE	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WXD1_k127_3278350_2	1121920.AUAU01000006_gene389	1.071e-25	119.0	2C3GN@1|root,31EWU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3278350_1	1049564.TevJSym_ap00120	4.816e-39	153.0	COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,1J6NS@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
WXD1_k127_3278350_5	1408473.JHXO01000009_gene3263	1.796e-08	66.0	2FFU4@1|root,347R8@2|Bacteria,4P5R2@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3278350_4	1276920.ADIAG_00581	8.227e-13	81.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,1W8I3@1268|Micrococcaceae	201174|Actinobacteria	P	ABC transporter	mntA	-	-	ko:K09820,ko:K11603,ko:K11607	ko02010,ko02020,map02010,map02020	M00243,M00316,M00317	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.1,3.A.1.15.7,3.A.1.15.9	-	-	ABC_tran
WXD1_k127_3278350_3	1192034.CAP_6622	4.221e-24	108.0	COG0317@1|root,COG0317@2|Bacteria,1RCK7@1224|Proteobacteria,42SEV@68525|delta/epsilon subdivisions,2WPK4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
WXD1_k127_3278350_0	234267.Acid_7947	2.454e-202	658.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_3287352_5	379066.GAU_0483	1.621e-53	199.0	COG0668@1|root,COG0668@2|Bacteria,1ZSU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
WXD1_k127_3287352_2	379066.GAU_0642	9.542e-74	266.0	COG0520@1|root,COG0520@2|Bacteria,1ZTDV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_3287352_6	929703.KE386491_gene262	3.069e-39	160.0	COG0791@1|root,COG0791@2|Bacteria,4NE2T@976|Bacteroidetes,47PND@768503|Cytophagia	976|Bacteroidetes	M	Cell wall-associated hydrolase (invasion-associated protein)	ykfC	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
WXD1_k127_3287352_9	1396858.Q666_16520	0.0002542	54.0	COG0860@1|root,COG1388@1|root,COG0860@2|Bacteria,COG1388@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,4647N@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,LysM
WXD1_k127_3287352_3	379066.GAU_0513	5.634e-72	266.0	COG2027@1|root,COG2027@2|Bacteria,1ZT1Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WXD1_k127_3287352_7	661478.OP10G_1421	7.916e-39	166.0	COG3707@1|root,COG3707@2|Bacteria	2|Bacteria	T	response regulator	gnfR	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,GAF_2,Response_reg
WXD1_k127_3287352_4	1128421.JAGA01000002_gene1646	6.558e-54	208.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	M1-573	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GAF,HATPase_c,HisKA,His_kinase,Response_reg
WXD1_k127_3287352_8	448385.sce6597	6.35e-05	56.0	2E5WH@1|root,330KI@2|Bacteria,1QAVR@1224|Proteobacteria,435BU@68525|delta/epsilon subdivisions,2WZPC@28221|Deltaproteobacteria,2Z2GK@29|Myxococcales	28221|Deltaproteobacteria	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WXD1_k127_3287352_1	861299.J421_0444	9.58e-194	616.0	COG0174@1|root,COG0174@2|Bacteria,1ZSYQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WXD1_k127_3287352_0	518766.Rmar_2149	6.854e-205	646.0	COG3968@1|root,COG3968@2|Bacteria,4NG2B@976|Bacteroidetes	976|Bacteroidetes	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
WXD1_k127_3308302_0	880073.Calab_3403	4.049e-293	917.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria	2|Bacteria	C	Malic enzyme, NAD binding domain	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K04020,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
WXD1_k127_3308302_2	861299.J421_2893	3.938e-19	100.0	2F044@1|root,33T7T@2|Bacteria	861299.J421_2893|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3308302_1	1120966.AUBU01000010_gene2870	1.143e-53	210.0	COG1228@1|root,COG1228@2|Bacteria,4NHGA@976|Bacteroidetes,47N43@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WXD1_k127_3327884_13	861299.J421_3172	3.501e-19	89.0	COG0745@1|root,COG0745@2|Bacteria,1ZU0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WXD1_k127_3327884_4	1125863.JAFN01000001_gene394	3.214e-149	483.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
WXD1_k127_3327884_7	379066.GAU_1544	8.893e-66	241.0	COG5000@1|root,COG5000@2|Bacteria,1ZSKZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
WXD1_k127_3327884_0	1379270.AUXF01000005_gene811	1.005e-233	746.0	COG0210@1|root,COG0210@2|Bacteria,1ZTD5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WXD1_k127_3327884_17	360910.BAV3177	4.458e-09	61.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,3T4GJ@506|Alcaligenaceae	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WXD1_k127_3327884_3	379066.GAU_1547	4.353e-152	502.0	COG0154@1|root,COG0154@2|Bacteria,1ZT24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WXD1_k127_3327884_5	944479.JQLX01000013_gene1342	1.126e-126	440.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2M6UY@213113|Desulfurellales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WXD1_k127_3327884_6	861299.J421_3181	1.483e-81	284.0	28Q1P@1|root,2ZB8E@2|Bacteria,1ZSPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
WXD1_k127_3327884_8	324925.Ppha_1066	6.582e-46	176.0	COG0388@1|root,COG0388@2|Bacteria,1FDC4@1090|Chlorobi	1090|Chlorobi	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
WXD1_k127_3327884_10	933262.AXAM01000014_gene262	3.522e-32	140.0	COG0025@1|root,COG0025@2|Bacteria,1N7PG@1224|Proteobacteria,42V45@68525|delta/epsilon subdivisions,2WRJ6@28221|Deltaproteobacteria,2MN9H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3327884_12	1480694.DC28_10460	2.78e-24	108.0	COG0347@1|root,COG0347@2|Bacteria,2J85W@203691|Spirochaetes	203691|Spirochaetes	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3327884_14	653733.Selin_0594	2.827e-13	76.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	AA_permease_2,PTS_EIIA_2,TrkA_C
WXD1_k127_3327884_2	861299.J421_3183	1.524e-175	561.0	COG0766@1|root,COG0766@2|Bacteria,1ZSZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WXD1_k127_3327884_9	379066.GAU_1552	6.56e-37	152.0	COG1496@1|root,COG1496@2|Bacteria,1ZTTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WXD1_k127_3327884_15	479433.Caci_1944	3.492e-11	72.0	2DG6U@1|root,2ZURF@2|Bacteria,2HCGM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3327884_18	1146883.BLASA_2870	0.0007555	45.0	2C59E@1|root,2ZDAY@2|Bacteria	2|Bacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
WXD1_k127_3327884_11	379066.GAU_1553	7.473e-26	112.0	COG0779@1|root,COG0779@2|Bacteria,1ZTX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
WXD1_k127_3327884_1	379066.GAU_1554	1.897e-176	565.0	COG0195@1|root,COG0195@2|Bacteria,1ZSNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
WXD1_k127_3327884_16	189425.PGRAT_18400	5.406e-11	69.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,26Y6Y@186822|Paenibacillaceae	91061|Bacilli	J	ribosomal protein	ylxQ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
WXD1_k127_334220_2	1112216.JH594425_gene1791	2.128e-05	57.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2U31V@28211|Alphaproteobacteria,2K3PY@204457|Sphingomonadales	204457|Sphingomonadales	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_334220_1	404589.Anae109_0683	3.969e-38	160.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43AKM@68525|delta/epsilon subdivisions,2X60K@28221|Deltaproteobacteria,2Z2WH@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WXD1_k127_334220_0	1379698.RBG1_1C00001G1210	7.493e-123	409.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_3369824_1	861299.J421_6034	1.547e-36	144.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,Guanylate_cyc,Trans_reg_C
WXD1_k127_3369824_2	861299.J421_1749	8.373e-28	121.0	2C30C@1|root,2ZV1M@2|Bacteria,1ZV6Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3369824_0	118168.MC7420_2481	1.54e-109	365.0	COG5549@1|root,COG5549@2|Bacteria,1GBTV@1117|Cyanobacteria	1117|Cyanobacteria	O	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3369824_3	1121106.JQKB01000059_gene4750	1.737e-22	100.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,2JVYF@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3408616_3	1278073.MYSTI_05670	1.367e-83	285.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,42NVR@68525|delta/epsilon subdivisions,2WM9A@28221|Deltaproteobacteria,2YU0T@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
WXD1_k127_3408616_1	404589.Anae109_0005	5.419e-121	410.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WXD1_k127_3408616_4	83406.HDN1F_32670	8.733e-29	119.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1J6QP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1393 Arsenate reductase and related proteins, glutaredoxin family	arsC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
WXD1_k127_3408616_0	861299.J421_1221	4.483e-136	452.0	COG0405@1|root,COG0405@2|Bacteria,1ZT8M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WXD1_k127_3408616_2	861299.J421_1999	1.915e-102	342.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT
WXD1_k127_341131_0	861299.J421_3566	7.256e-289	904.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WXD1_k127_341131_1	1123371.ATXH01000038_gene1354	6.714e-11	64.0	COG1057@1|root,COG1057@2|Bacteria,2GGX6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WXD1_k127_3423551_5	1198452.Jab_2c06620	3.294e-46	180.0	COG4299@1|root,COG4299@2|Bacteria,1RDP3@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
WXD1_k127_3423551_4	1223523.H340_30873	2.238e-54	195.0	COG2606@1|root,COG2606@2|Bacteria,2IHS8@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WXD1_k127_3423551_6	929712.KI912613_gene2917	2.378e-25	121.0	COG1629@1|root,COG4771@2|Bacteria,2IN13@201174|Actinobacteria	201174|Actinobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3423551_1	485917.Phep_0681	4.083e-127	410.0	COG4821@1|root,COG4821@2|Bacteria,4NHQW@976|Bacteroidetes,1ITT0@117747|Sphingobacteriia	976|Bacteroidetes	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
WXD1_k127_3423551_3	485917.Phep_0680	1.003e-80	284.0	COG0738@1|root,COG0738@2|Bacteria,4NHZ7@976|Bacteroidetes,1INTY@117747|Sphingobacteriia	976|Bacteroidetes	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WXD1_k127_3423551_2	929713.NIASO_16385	9.654e-93	317.0	COG1940@1|root,COG1940@2|Bacteria,4NHNJ@976|Bacteroidetes,1IUUW@117747|Sphingobacteriia	976|Bacteroidetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WXD1_k127_3423551_0	177439.DP0309	5.326e-158	516.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_5,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
WXD1_k127_3432734_0	234267.Acid_3530	0.0	1202.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WXD1_k127_3439712_9	156889.Mmc1_0885	1.578e-05	53.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hoxW	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WXD1_k127_3439712_1	316067.Geob_1632	6.541e-116	398.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
WXD1_k127_3439712_3	374847.Kcr_0321	1.494e-97	333.0	COG0374@1|root,arCOG01549@2157|Archaea	2157|Archaea	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hydA	GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494	1.12.1.3,1.12.1.5,1.8.98.5	ko:K14126,ko:K17993	ko00680,ko00920,map00680,map00920	-	R00019,R10390,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WXD1_k127_3439712_7	316067.Geob_1892	1.242e-58	213.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42U69@68525|delta/epsilon subdivisions,2WQJZ@28221|Deltaproteobacteria,43USH@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hyhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
WXD1_k127_3439712_4	648996.Theam_0486	2.753e-96	323.0	COG0543@1|root,COG0543@2|Bacteria,2G45B@200783|Aquificae	200783|Aquificae	C	Oxidoreductase NAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WXD1_k127_3439712_5	156889.Mmc1_0881	1.155e-80	282.0	COG0479@1|root,COG0479@2|Bacteria,1QVWG@1224|Proteobacteria,2TWVH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
WXD1_k127_3439712_8	880073.Calab_0422	6.538e-20	99.0	COG0745@1|root,COG0745@2|Bacteria,2NRCE@2323|unclassified Bacteria	2|Bacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WXD1_k127_3439712_6	644282.Deba_1749	5.436e-66	241.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
WXD1_k127_3439712_0	1379270.AUXF01000005_gene339	9.729e-288	901.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSND@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WXD1_k127_3439712_2	379066.GAU_3212	9.868e-113	381.0	COG0006@1|root,COG0006@2|Bacteria,1ZUGP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WXD1_k127_3453796_2	1078085.HMPREF1210_03334	2.915e-33	132.0	COG0346@1|root,COG0346@2|Bacteria,1VCGT@1239|Firmicutes,4HKDV@91061|Bacilli,26FTE@186818|Planococcaceae	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WXD1_k127_3453796_3	864702.OsccyDRAFT_1447	2.076e-21	101.0	COG1510@1|root,COG1510@2|Bacteria,1GDM6@1117|Cyanobacteria,1HFEG@1150|Oscillatoriales	1117|Cyanobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WXD1_k127_3453796_0	379066.GAU_2874	4.744e-100	343.0	COG1538@1|root,COG1538@2|Bacteria,1ZUXT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WXD1_k127_3453796_1	379066.GAU_2873	3.047e-60	224.0	COG0845@1|root,COG0845@2|Bacteria,1ZSR2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WXD1_k127_3459209_0	1239962.C943_02112	4.654e-138	447.0	COG2866@1|root,COG2866@2|Bacteria,4NIJ0@976|Bacteroidetes,47K8F@768503|Cytophagia	976|Bacteroidetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WXD1_k127_3459209_3	1123399.AQVE01000022_gene386	8.042e-41	154.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0145 family	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WXD1_k127_3459209_1	379066.GAU_2208	7.277e-117	401.0	COG0451@1|root,COG0451@2|Bacteria,1ZUAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	NAD dependent epimerase/dehydratase family	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	Epimerase
WXD1_k127_3459209_2	290397.Adeh_1509	3.495e-61	222.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2WJV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the phosphatidylserine decarboxylase family	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
WXD1_k127_3464818_5	269799.Gmet_0069	3.739e-37	145.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria,43V13@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
WXD1_k127_3464818_0	379066.GAU_0790	3.122e-204	658.0	COG0272@1|root,COG0272@2|Bacteria,1ZT5Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WXD1_k127_3464818_9	1120985.AUMI01000016_gene1882	8.374e-05	51.0	COG1719@1|root,COG1719@2|Bacteria,1V2C7@1239|Firmicutes,4H4AQ@909932|Negativicutes	909932|Negativicutes	S	V4R	-	-	-	-	-	-	-	-	-	-	-	-	V4R
WXD1_k127_3464818_6	383372.Rcas_3713	3.043e-27	115.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi,375V0@32061|Chloroflexia	32061|Chloroflexia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WXD1_k127_3464818_1	861299.J421_2620	8.06e-74	262.0	COG1559@1|root,COG1559@2|Bacteria,1ZTA7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WXD1_k127_3464818_3	1304874.JAFY01000005_gene1396	6.426e-44	180.0	COG0352@1|root,COG0352@2|Bacteria,3TBAB@508458|Synergistetes	508458|Synergistetes	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
WXD1_k127_3464818_2	246197.MXAN_3119	6.032e-56	206.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,42P6V@68525|delta/epsilon subdivisions,2WM6M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
WXD1_k127_3464818_4	929703.KE386491_gene280	4.178e-41	153.0	2AU0F@1|root,31JKB@2|Bacteria,4NHS6@976|Bacteroidetes,47Q5C@768503|Cytophagia	976|Bacteroidetes	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3478294_0	420662.Mpe_A2932	5.282e-35	143.0	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,2WGGE@28216|Betaproteobacteria	28216|Betaproteobacteria	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WXD1_k127_3478294_2	443143.GM18_2815	1.22e-17	92.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6Z3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,Sigma54_activat
WXD1_k127_3478294_3	1217656.F964_00080	2.642e-07	63.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,1RPTU@1236|Gammaproteobacteria,3NK4V@468|Moraxellaceae	1236|Gammaproteobacteria	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
WXD1_k127_3479401_2	1230341.MJ3_11125	5.61e-116	389.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WXD1_k127_3479401_9	1379698.RBG1_1C00001G1439	5.625e-25	107.0	COG2331@1|root,COG2331@2|Bacteria,2NQ36@2323|unclassified Bacteria	2|Bacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WXD1_k127_3479401_0	986075.CathTA2_1034	9.3e-218	687.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WXD1_k127_3479401_6	1379270.AUXF01000006_gene115	5.488e-41	157.0	COG4770@1|root,COG4770@2|Bacteria,1ZTVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
WXD1_k127_3479401_4	1118054.CAGW01000055_gene2578	2.07e-56	225.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,26R13@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rlmCD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WXD1_k127_3479401_1	518766.Rmar_2362	2.02e-170	554.0	COG1215@1|root,COG1215@2|Bacteria,4NH18@976|Bacteroidetes,1FJVU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family 21	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,Sulfatase
WXD1_k127_3479401_8	518766.Rmar_2361	1.419e-30	136.0	COG1413@1|root,COG1413@2|Bacteria,4PF5C@976|Bacteroidetes,1FK66@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3479401_5	518766.Rmar_2360	1.348e-46	181.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,4NQNT@976|Bacteroidetes	976|Bacteroidetes	T	PFAM Response regulator receiver domain	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WXD1_k127_3479401_7	335543.Sfum_2207	1.873e-32	130.0	COG0745@1|root,COG0745@2|Bacteria,1QZ4A@1224|Proteobacteria,43CF7@68525|delta/epsilon subdivisions,2X7Q9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WXD1_k127_3479401_3	523845.AQXV01000046_gene852	4.606e-115	381.0	COG0439@1|root,arCOG01590@2157|Archaea,2Y8CM@28890|Euryarchaeota,23QDY@183939|Methanococci	183939|Methanococci	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	pycA	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WXD1_k127_348143_0	1122603.ATVI01000005_gene3500	1.875e-47	190.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S1MS@1236|Gammaproteobacteria,1X9I0@135614|Xanthomonadales	135614|Xanthomonadales	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
WXD1_k127_349184_1	526227.Mesil_2957	2.706e-145	470.0	COG0156@1|root,COG0156@2|Bacteria,1WIXA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WXD1_k127_349184_2	504728.K649_13715	5.297e-131	426.0	COG0451@1|root,COG0451@2|Bacteria,1WNCR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM NAD dependent epimerase dehydratase family	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
WXD1_k127_349184_3	1379270.AUXF01000006_gene163	2.287e-109	365.0	COG0547@1|root,COG0547@2|Bacteria,1ZTDS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
WXD1_k127_349184_4	379066.GAU_1726	5.884e-83	280.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WXD1_k127_349184_5	1089553.Tph_c26520	1.854e-60	219.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,42EQ2@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
WXD1_k127_349184_6	1123247.AUIJ01000001_gene1795	7.978e-30	127.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2U7CH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
WXD1_k127_349184_0	379066.GAU_1723	1.39e-167	545.0	COG0133@1|root,COG0133@2|Bacteria,1ZSUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WXD1_k127_349184_7	1379270.AUXF01000006_gene168	8.079e-27	121.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WXD1_k127_3497213_3	411490.ANACAC_00558	0.0003692	52.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
WXD1_k127_3497213_1	379066.GAU_2197	1.243e-81	303.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	XK27_02140	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	5_nucleotid_C,CHB_HEX_C_1,Calx-beta,Exo_endo_phos,Gram_pos_anchor,HemolysinCabind,LTD,Metallophos,SLH
WXD1_k127_3497213_4	1227739.Hsw_1796	0.0004194	54.0	COG1502@1|root,COG4085@1|root,COG1502@2|Bacteria,COG4085@2|Bacteria	2|Bacteria	S	PFAM nucleic acid binding, OB-fold, tRNA	comA	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	HHH_3,PLDc_2
WXD1_k127_3497213_2	379066.GAU_2198	2.583e-51	196.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,He_PIG,SLH
WXD1_k127_3497213_0	379066.GAU_2199	2.647e-115	385.0	COG1629@1|root,COG4771@2|Bacteria,1ZUQM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WXD1_k127_3510156_0	861299.J421_4545	7.487e-122	422.0	COG1864@1|root,COG2374@1|root,COG3291@1|root,COG1864@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,1ZUE4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	DNA/RNA non-specific endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Endonuclease_NS,PKD
WXD1_k127_35352_1	69395.JQLZ01000007_gene1589	3.678e-226	715.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2KI6R@204458|Caulobacterales	204458|Caulobacterales	E	leukotriene A-4 hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Leuk-A4-hydro_C,Peptidase_M1
WXD1_k127_35352_10	1379270.AUXF01000001_gene2568	9.527e-42	161.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_35352_13	187272.Mlg_1635	2.622e-08	60.0	COG5662@1|root,COG5662@2|Bacteria,1NG37@1224|Proteobacteria,1ST5G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WXD1_k127_35352_12	861299.J421_2526	5.459e-29	123.0	COG2802@1|root,COG2802@2|Bacteria,1ZUZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
WXD1_k127_35352_3	1121104.AQXH01000008_gene2418	1.134e-141	461.0	COG2159@1|root,COG2159@2|Bacteria,4NG9U@976|Bacteroidetes,1IWYY@117747|Sphingobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WXD1_k127_35352_8	251221.35210598	2.754e-46	170.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WXD1_k127_35352_11	379066.GAU_1047	3.206e-40	160.0	2A0JD@1|root,30NPJ@2|Bacteria,1ZUVV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WXD1_k127_35352_7	926549.KI421517_gene3572	1.404e-49	192.0	COG0739@1|root,COG0739@2|Bacteria,4NEBZ@976|Bacteroidetes,47JJ1@768503|Cytophagia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3,SH3_4
WXD1_k127_35352_2	880073.Calab_1713	3.249e-158	514.0	COG1660@1|root,COG3178@1|root,COG1660@2|Bacteria,COG3178@2|Bacteria,2NP9G@2323|unclassified Bacteria	2|Bacteria	S	P-loop ATPase protein family	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K06958,ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000,ko03019	-	-	-	APH,ATP_bind_2
WXD1_k127_35352_6	742817.HMPREF9449_02560	1.022e-54	209.0	COG1208@1|root,COG1208@2|Bacteria,4NMJ5@976|Bacteroidetes,2FNEE@200643|Bacteroidia,22XKJ@171551|Porphyromonadaceae	976|Bacteroidetes	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	hddC	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
WXD1_k127_35352_4	1396418.BATQ01000149_gene2216	1.68e-107	365.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
WXD1_k127_35352_0	1288963.ADIS_2023	9.271e-273	863.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,47JTT@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
WXD1_k127_35352_9	861299.J421_3698	7.428e-46	169.0	COG2967@1|root,COG2967@2|Bacteria,1ZTR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ApaG domain	-	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
WXD1_k127_35352_14	643562.Daes_3233	5.025e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1Q1DV@1224|Proteobacteria,432YX@68525|delta/epsilon subdivisions,2WX66@28221|Deltaproteobacteria,2MFQX@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
WXD1_k127_35352_5	861299.J421_4374	2.434e-90	336.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1ZT3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LV	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
WXD1_k127_3538492_2	326427.Cagg_1321	3.633e-65	233.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WXD1_k127_3538492_1	861299.J421_2109	1.258e-98	335.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WXD1_k127_3538492_0	861299.J421_2847	0.0	1100.0	COG0209@1|root,COG0209@2|Bacteria,1ZSU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
WXD1_k127_3540387_0	861299.J421_2228	3.025e-81	284.0	COG0702@1|root,COG0702@2|Bacteria,1ZV6Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
WXD1_k127_3540387_1	861299.J421_1521	1.651e-41	155.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	fecB	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WXD1_k127_354577_2	861299.J421_3354	0.0004153	49.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
WXD1_k127_354577_1	379066.GAU_1714	6.263e-117	385.0	COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
WXD1_k127_354577_0	292459.STH2421	4.976e-128	422.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WXD1_k127_3601357_1	1245469.S58_71810	8.386e-68	235.0	COG0507@1|root,COG1112@1|root,COG2251@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2251@2|Bacteria,1MWW9@1224|Proteobacteria,2TTSD@28211|Alphaproteobacteria,3JQNN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,AAA_30,RNase_H_2
WXD1_k127_3601357_5	105559.Nwat_1260	4.584e-09	62.0	2A6UU@1|root,30VP8@2|Bacteria,1NQ5B@1224|Proteobacteria,1SUYT@1236|Gammaproteobacteria,1X1Y1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3601357_4	446471.Xcel_3163	1.718e-19	97.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WXD1_k127_3601357_2	861299.J421_1728	3.52e-54	219.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WXD1_k127_3601357_0	861299.J421_5846	3.727e-94	338.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
WXD1_k127_3601357_3	502025.Hoch_5753	2.086e-26	123.0	COG2378@1|root,COG2378@2|Bacteria,1QAGU@1224|Proteobacteria,434D3@68525|delta/epsilon subdivisions,2WYQ2@28221|Deltaproteobacteria,2Z0CG@29|Myxococcales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
WXD1_k127_3640647_1	861299.J421_1109	2.364e-70	248.0	COG1132@1|root,COG1132@2|Bacteria,1ZUSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
WXD1_k127_3640647_0	1379270.AUXF01000001_gene2421	5.095e-223	705.0	COG0405@1|root,COG0405@2|Bacteria,1ZUIG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WXD1_k127_3652554_2	653733.Selin_2151	2.017e-83	297.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
WXD1_k127_3652554_1	1278073.MYSTI_06113	6.386e-89	309.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2WNZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
WXD1_k127_3652554_4	278957.ABEA03000019_gene1944	3.091e-34	137.0	COG2010@1|root,COG2010@2|Bacteria,46SVP@74201|Verrucomicrobia,3K83H@414999|Opitutae	414999|Opitutae	C	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
WXD1_k127_3652554_5	296591.Bpro_4303	0.000695	46.0	COG4736@1|root,COG4736@2|Bacteria,1PUF6@1224|Proteobacteria,2VXME@28216|Betaproteobacteria,4AFTD@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Cbb3-type cytochrome oxidase component	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
WXD1_k127_3652554_3	929562.Emtol_0368	1.904e-80	278.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,4NEGM@976|Bacteroidetes,47MI5@768503|Cytophagia	976|Bacteroidetes	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
WXD1_k127_3652554_0	1297742.A176_05050	2.826e-205	646.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2WM27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
WXD1_k127_3670563_4	861299.J421_0907	2.982e-78	267.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_3670563_2	861299.J421_2400	2.394e-133	457.0	COG1748@1|root,COG1748@2|Bacteria,1ZSMC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WXD1_k127_3670563_1	861299.J421_2591	2.035e-158	530.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WXD1_k127_3670563_3	266117.Rxyl_1756	9.922e-120	393.0	COG3396@1|root,COG3396@2|Bacteria,2GMQ3@201174|Actinobacteria,4CQIA@84995|Rubrobacteria	84995|Rubrobacteria	S	phenylacetic acid catabolic	-	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
WXD1_k127_3670563_6	1120973.AQXL01000095_gene246	2.174e-26	116.0	COG2151@1|root,COG2151@2|Bacteria,1VE3S@1239|Firmicutes,4HKP6@91061|Bacilli	91061|Bacilli	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
WXD1_k127_3670563_7	1111479.AXAR01000003_gene1557	6.362e-12	68.0	2DTNH@1|root,33M2H@2|Bacteria,1W1AW@1239|Firmicutes,4HZ7K@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3670563_5	1382306.JNIM01000001_gene267	8.662e-39	156.0	COG3396@1|root,COG3396@2|Bacteria,2G9KQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phenylacetic acid catabolic family protein	-	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
WXD1_k127_3670563_8	1118054.CAGW01000061_gene2431	0.0001024	46.0	2DFWV@1|root,2ZTI9@2|Bacteria,1W53S@1239|Firmicutes,4HZK2@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3670563_0	1379270.AUXF01000004_gene3237	4.487e-168	555.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WXD1_k127_3692832_0	1379270.AUXF01000005_gene591	4.106e-150	481.0	COG0441@1|root,COG0441@2|Bacteria,1ZT2I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WXD1_k127_3692832_2	379066.GAU_1878	6.542e-66	230.0	COG0290@1|root,COG0290@2|Bacteria,1ZTM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WXD1_k127_3692832_5	177439.DP1426	2.356e-17	83.0	COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2WREY@28221|Deltaproteobacteria,2MM1F@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WXD1_k127_3692832_3	429009.Adeg_0536	6.095e-36	139.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,42GJ4@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WXD1_k127_3692832_1	713586.KB900536_gene358	1.74e-109	365.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1WXAD@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WXD1_k127_3692832_4	1120973.AQXL01000099_gene3270	5.045e-23	110.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli,2787I@186823|Alicyclobacillaceae	91061|Bacilli	J	phenylalanyl-tRNA synthetase beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WXD1_k127_3701213_9	357808.RoseRS_1950	1.657e-58	212.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WXD1_k127_3701213_1	379066.GAU_1104	3.931e-155	503.0	COG0469@1|root,COG0469@2|Bacteria,1ZSMD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WXD1_k127_3701213_6	1379270.AUXF01000005_gene378	5.983e-85	296.0	COG1235@1|root,COG1235@2|Bacteria,1ZT49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
WXD1_k127_3701213_3	861299.J421_2873	1.627e-137	451.0	COG0166@1|root,COG0166@2|Bacteria,1ZU5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WXD1_k127_3701213_12	429009.Adeg_0221	3.544e-42	169.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,42F8X@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WXD1_k127_3701213_15	1121861.KB899921_gene3054	1.243e-06	58.0	COG5002@1|root,COG5002@2|Bacteria,1QU7C@1224|Proteobacteria,2TWBW@28211|Alphaproteobacteria,2JPN9@204441|Rhodospirillales	204441|Rhodospirillales	T	Stimulus-sensing domain	chvG	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
WXD1_k127_3701213_2	861299.J421_2876	3.075e-153	496.0	COG2204@1|root,COG2204@2|Bacteria,1ZSW0@142182|Gemmatimonadetes	2|Bacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_3701213_14	379066.GAU_1108	2.374e-07	58.0	COG4980@1|root,COG4980@2|Bacteria,1ZU46@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
WXD1_k127_3701213_13	861299.J421_2878	7.492e-41	167.0	COG1295@1|root,COG1295@2|Bacteria,1ZTHX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WXD1_k127_3701213_11	1234664.AMRO01000028_gene1518	2.993e-48	179.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli,1WF9E@129337|Geobacillus	91061|Bacilli	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WXD1_k127_3701213_10	1379270.AUXF01000003_gene3876	1.094e-49	192.0	COG0860@1|root,COG0860@2|Bacteria,1ZSUX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
WXD1_k127_3701213_16	309807.SRU_1028	4.297e-06	60.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NDV9@976|Bacteroidetes,1FJ3F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Tetratricopeptide repeat	sprE	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
WXD1_k127_3701213_5	861299.J421_3582	3.165e-90	308.0	COG0167@1|root,COG0167@2|Bacteria,1ZT86@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WXD1_k127_3701213_8	861299.J421_3581	8.44e-59	212.0	COG0284@1|root,COG0284@2|Bacteria,1ZTQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WXD1_k127_3701213_7	1123376.AUIU01000018_gene50	2.393e-66	238.0	COG0668@1|root,COG0668@2|Bacteria,3J0YK@40117|Nitrospirae	40117|Nitrospirae	M	Mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
WXD1_k127_3701213_4	1267535.KB906767_gene4734	1.257e-128	441.0	COG0215@1|root,COG0215@2|Bacteria,3Y2PW@57723|Acidobacteria,2JHIQ@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
WXD1_k127_3701213_0	1278073.MYSTI_01766	1.687e-163	544.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_370514_15	1297742.A176_02646	3.491e-17	87.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,42P4Q@68525|delta/epsilon subdivisions,2WK5G@28221|Deltaproteobacteria,2YU4N@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WXD1_k127_370514_12	751945.Theos_1608	4.969e-32	131.0	COG2332@1|root,COG2332@2|Bacteria,1WJVR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
WXD1_k127_370514_9	1089546.AQUI01000002_gene3234	3.832e-59	213.0	COG0755@1|root,COG0755@2|Bacteria,2IIHK@201174|Actinobacteria	201174|Actinobacteria	O	cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
WXD1_k127_370514_11	671143.DAMO_1591	6.448e-44	173.0	COG2386@1|root,COG2386@2|Bacteria,2NPSF@2323|unclassified Bacteria	2|Bacteria	O	CcmB protein	ccmB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.41	ko:K02193,ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	iECO111_1330.ECO111_2936,iYL1228.KPN_02080	CcmB
WXD1_k127_370514_10	479434.Sthe_1412	8.158e-48	180.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi,27YFZ@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
WXD1_k127_370514_1	756067.MicvaDRAFT_5490	2.056e-171	550.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria,1H8G7@1150|Oscillatoriales	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
WXD1_k127_370514_13	402777.KB235903_gene2187	2.438e-30	122.0	COG3288@1|root,COG3288@2|Bacteria,1G711@1117|Cyanobacteria,1HBSG@1150|Oscillatoriales	1117|Cyanobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA-2	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
WXD1_k127_370514_5	1173025.GEI7407_3430	2.1e-114	380.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1H7A5@1150|Oscillatoriales	1117|Cyanobacteria	C	NAD NADP transhydrogenase alpha subunit	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
WXD1_k127_370514_4	404589.Anae109_2847	1.2e-131	432.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria,42YA5@68525|delta/epsilon subdivisions,2WU6I@28221|Deltaproteobacteria,2Z3J0@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
WXD1_k127_370514_7	861299.J421_2448	1.235e-79	286.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,1ZTZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WXD1_k127_370514_0	1173025.GEI7407_1132	1.832e-183	606.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9
WXD1_k127_370514_6	861299.J421_3670	1.041e-88	302.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.4.11.2,3.5.2.6	ko:K01256,ko:K17836	ko00311,ko00480,ko01100,ko01130,ko01501,map00311,map00480,map01100,map01130,map01501	M00627,M00628	R00899,R04951,R06363	RC00096,RC00141,RC01499	ko00000,ko00001,ko00002,ko01000,ko01002,ko01504	-	-	-	Beta-lactamase,Beta-lactamase2
WXD1_k127_370514_8	861299.J421_3671	3.808e-70	244.0	2F2ZI@1|root,33VUW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_370514_3	861299.J421_3672	4.747e-145	480.0	2EYW5@1|root,33S36@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_370514_14	525146.Ddes_1070	1.736e-17	98.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria,2M82M@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_370514_2	1232410.KI421414_gene2832	3.056e-154	507.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,43SYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
WXD1_k127_370514_16	861299.J421_4260	1.521e-05	52.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_3731043_4	590998.Celf_2549	7.566e-48	185.0	COG1785@1|root,COG1785@2|Bacteria,2GM8A@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the alkaline phosphatase family	phoA	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
WXD1_k127_3731043_1	1191523.MROS_2800	1.314e-224	701.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gluD	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.gdhA	ELFV_dehydrog,ELFV_dehydrog_N
WXD1_k127_3731043_0	880073.Calab_2356	3.056e-265	838.0	COG0574@1|root,COG0574@2|Bacteria,2NQHP@2323|unclassified Bacteria	2|Bacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_2,PPDK_N,Response_reg
WXD1_k127_3731043_8	861299.J421_1225	8.81e-08	62.0	COG3279@1|root,COG3279@2|Bacteria,1ZTKG@142182|Gemmatimonadetes	2|Bacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	EAL,LytTR,Response_reg
WXD1_k127_3731043_2	1128421.JAGA01000002_gene1840	5.397e-207	653.0	COG2270@1|root,COG2270@2|Bacteria,2NP3G@2323|unclassified Bacteria	2|Bacteria	S	Vacuole effluxer Atg22 like	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22,MFS_1
WXD1_k127_3731043_3	861299.J421_5669	6.549e-51	186.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
WXD1_k127_3731043_5	861299.J421_0407	3.726e-27	123.0	COG3278@1|root,COG3278@2|Bacteria,1ZU6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
WXD1_k127_3731043_7	861299.J421_0405	6.016e-09	66.0	2ETH9@1|root,33M15@2|Bacteria	2|Bacteria	S	Domain of Unknown function (DUF542)	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	ScdA_N
WXD1_k127_3731043_6	861299.J421_0406	5.078e-12	74.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,Cupin_7
WXD1_k127_3740594_2	414684.RC1_2426	2.914e-98	343.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2JPJ7@204441|Rhodospirillales	204441|Rhodospirillales	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
WXD1_k127_3740594_1	1379270.AUXF01000004_gene3297	4.404e-206	655.0	COG1239@1|root,COG1239@2|Bacteria,1ZT0R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
WXD1_k127_3740594_3	1121877.JQKF01000018_gene2547	2.137e-45	175.0	COG0494@1|root,COG0494@2|Bacteria,2GN6D@201174|Actinobacteria,4CN1R@84992|Acidimicrobiia	84992|Acidimicrobiia	L	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3740594_0	379066.GAU_1936	7.081e-275	857.0	COG2987@1|root,COG2987@2|Bacteria,1ZSQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
WXD1_k127_3740594_4	861299.J421_2921	2.328e-29	124.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WXD1_k127_37509_5	861299.J421_3946	6.09e-20	95.0	COG0636@1|root,COG0636@2|Bacteria,1ZU1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WXD1_k127_37509_1	861299.J421_3947	5.74e-75	261.0	COG0356@1|root,COG0356@2|Bacteria,1ZSQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WXD1_k127_37509_6	797302.Halru_0872	3.148e-11	69.0	arCOG08936@1|root,arCOG08936@2157|Archaea,2XYCQ@28890|Euryarchaeota,23WHK@183963|Halobacteria	183963|Halobacteria	M	Intracellular proteinase inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI
WXD1_k127_37509_0	861299.J421_3951	5.558e-136	440.0	COG0714@1|root,COG0714@2|Bacteria,1ZT5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WXD1_k127_37509_3	521011.Mpal_0531	4.196e-61	227.0	COG1253@1|root,arCOG00626@2157|Archaea,2XT1Z@28890|Euryarchaeota,2N962@224756|Methanomicrobia	224756|Methanomicrobia	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WXD1_k127_37509_2	867903.ThesuDRAFT_00419	5.735e-62	228.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3WCTC@538999|Clostridiales incertae sedis	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,PALP
WXD1_k127_37509_4	1118054.CAGW01000061_gene2437	2.136e-48	178.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,4HFPC@91061|Bacilli,26X34@186822|Paenibacillaceae	91061|Bacilli	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	caiE	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WXD1_k127_37509_7	195250.CM001776_gene2481	8.031e-05	55.0	COG0665@1|root,COG0665@2|Bacteria,1GPXB@1117|Cyanobacteria,1GZ0V@1129|Synechococcus	1117|Cyanobacteria	E	COG0665 Glycine D-amino acid oxidases (deaminating)	thiO	-	1.4.3.19,2.8.1.10	ko:K03149,ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463,R10247	RC01788,RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	DAO
WXD1_k127_3753903_3	1449049.JONW01000005_gene866	6.376e-12	71.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
WXD1_k127_3753903_0	861299.J421_4111	4.093e-299	959.0	COG0642@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	bvgS	-	2.7.13.3	ko:K07679,ko:K10439	ko02010,ko02020,ko02030,ko05133,map02010,map02020,map02030,map05133	M00212,M00477	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
WXD1_k127_3753903_1	861299.J421_4112	4.968e-85	295.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1ZTRB@142182|Gemmatimonadetes	861299.J421_4112|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3753903_2	861299.J421_4113	2.422e-74	259.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_4113|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3770267_0	880073.Calab_0388	1.516e-146	475.0	COG2195@1|root,COG2195@2|Bacteria,2NPYT@2323|unclassified Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0034701,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045148,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
WXD1_k127_3770267_1	234267.Acid_3259	3.934e-91	304.0	COG1297@1|root,COG1297@2|Bacteria,3Y3SD@57723|Acidobacteria	57723|Acidobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
WXD1_k127_3784521_5	134676.ACPL_1294	2.728e-77	271.0	COG0501@1|root,COG0501@2|Bacteria,2GKJQ@201174|Actinobacteria,4DBRM@85008|Micromonosporales	201174|Actinobacteria	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WXD1_k127_3784521_1	936573.HMPREF1147_0928	3.711e-127	420.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4H1YR@909932|Negativicutes	909932|Negativicutes	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
WXD1_k127_3784521_7	326427.Cagg_1584	5.572e-58	213.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi,376AI@32061|Chloroflexia	32061|Chloroflexia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WXD1_k127_3784521_2	1297742.A176_05689	1.622e-109	366.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2YXMW@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG type nucleases (URI domain)	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	UVR
WXD1_k127_3784521_8	861299.J421_3903	3.105e-42	161.0	COG0622@1|root,COG0622@2|Bacteria,1ZTSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
WXD1_k127_3784521_6	861299.J421_3904	1.614e-70	254.0	COG0163@1|root,COG0163@2|Bacteria,1ZTIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
WXD1_k127_3784521_3	861299.J421_3905	1.881e-84	294.0	COG0382@1|root,COG0382@2|Bacteria,1ZT35@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WXD1_k127_3784521_0	861299.J421_3906	5.378e-198	629.0	COG0043@1|root,COG0043@2|Bacteria,1ZSMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
WXD1_k127_3784521_9	981369.JQMJ01000004_gene3763	5.961e-17	93.0	COG2020@1|root,COG2020@2|Bacteria,2HUDA@201174|Actinobacteria,2NIQ9@228398|Streptacidiphilus	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WXD1_k127_3784521_4	1254432.SCE1572_33565	5.012e-79	273.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
WXD1_k127_3833799_3	861299.J421_4129	4.957e-198	638.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
WXD1_k127_3833799_0	861299.J421_4130	4.006e-317	1000.0	COG1629@1|root,COG4771@2|Bacteria,1ZVAQ@142182|Gemmatimonadetes	2|Bacteria	P	TonB dependent receptor	susC	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_3833799_2	1265503.KB905161_gene3151	5.678e-223	721.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WXD1_k127_3833799_4	1121346.KB899827_gene495	1.247e-98	351.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,4HBYA@91061|Bacilli,277A8@186822|Paenibacillaceae	91061|Bacilli	G	Arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
WXD1_k127_3833799_1	452637.Oter_2611	3.799e-232	767.0	COG2120@1|root,COG2120@2|Bacteria,46UF1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WXD1_k127_3833799_5	368407.Memar_2281	6.541e-89	302.0	COG0557@1|root,arCOG04686@2157|Archaea,2XT2E@28890|Euryarchaeota,2NA9N@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
WXD1_k127_3870192_4	861299.J421_3711	3.05e-38	149.0	COG1024@1|root,COG1024@2|Bacteria,1ZSTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
WXD1_k127_3870192_1	391625.PPSIR1_25066	2.125e-93	323.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42PBC@68525|delta/epsilon subdivisions,2WM7S@28221|Deltaproteobacteria,2YY2B@29|Myxococcales	28221|Deltaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WXD1_k127_3870192_2	795797.C497_01570	2.958e-58	223.0	COG1024@1|root,arCOG00239@2157|Archaea,2XTF0@28890|Euryarchaeota,23SMM@183963|Halobacteria	183963|Halobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
WXD1_k127_3870192_7	756883.Halar_3553	1.025e-14	85.0	COG1024@1|root,arCOG00239@2157|Archaea	2157|Archaea	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
WXD1_k127_3870192_3	28258.KP05_01715	2.344e-54	210.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1XHSG@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WXD1_k127_3870192_0	861299.J421_1402	6.557e-245	784.0	COG2091@1|root,COG2091@2|Bacteria,1ZUPU@142182|Gemmatimonadetes	2|Bacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WXD1_k127_3870192_5	1173027.Mic7113_0229	6.709e-32	125.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,1HCCX@1150|Oscillatoriales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WXD1_k127_3876951_12	1122179.KB890430_gene4348	0.0005947	49.0	COG3825@1|root,COG4206@1|root,COG3825@2|Bacteria,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	FGE-sulfatase,VWA_CoxE
WXD1_k127_3876951_0	861299.J421_0447	1.229e-114	376.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
WXD1_k127_3876951_6	861299.J421_4371	1.491e-72	262.0	COG1215@1|root,COG1215@2|Bacteria,1ZU0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 21	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WXD1_k127_3876951_2	1382306.JNIM01000001_gene1964	2.491e-112	374.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	ycbU	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_3876951_7	1121472.AQWN01000002_gene2258	1.693e-38	148.0	COG1694@1|root,COG1694@2|Bacteria,1V701@1239|Firmicutes,24KA0@186801|Clostridia,2621J@186807|Peptococcaceae	186801|Clostridia	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
WXD1_k127_3876951_1	1128421.JAGA01000003_gene3228	2.323e-113	375.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WXD1_k127_3876951_11	379066.GAU_2852	1.33e-05	58.0	2FDUV@1|root,345VG@2|Bacteria,1ZTXA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3876951_5	1128421.JAGA01000003_gene2936	1.15e-79	279.0	COG0506@1|root,COG0506@2|Bacteria,2NPED@2323|unclassified Bacteria	2|Bacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
WXD1_k127_3876951_4	1500893.JQNB01000001_gene291	1.438e-82	279.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1X4FR@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
WXD1_k127_3876951_9	861299.J421_4480	1.921e-22	103.0	COG1403@1|root,COG1403@2|Bacteria,1ZV49@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
WXD1_k127_3876951_8	1379270.AUXF01000001_gene2642	3.342e-38	151.0	COG1051@1|root,COG1051@2|Bacteria,1ZU0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WXD1_k127_3876951_10	469383.Cwoe_4403	1.266e-21	100.0	COG1071@1|root,COG1071@2|Bacteria,2IC03@201174|Actinobacteria,4CQ7Q@84995|Rubrobacteria	84995|Rubrobacteria	C	PFAM dehydrogenase, E1 component	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh
WXD1_k127_3896271_3	379066.GAU_2872	7.338e-15	75.0	COG0841@1|root,COG0841@2|Bacteria,1ZUFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WXD1_k127_3896271_2	1158292.JPOE01000002_gene2110	2.087e-59	219.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2VR7A@28216|Betaproteobacteria,1KNN0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
WXD1_k127_3896271_0	379066.GAU_3599	2.649e-102	353.0	COG0596@1|root,COG0596@2|Bacteria,1ZUKC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3896271_1	379066.GAU_3732	6.743e-79	286.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WXD1_k127_3905190_9	861299.J421_2715	3.464e-54	195.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WXD1_k127_3905190_6	1340493.JNIF01000004_gene730	1.846e-71	266.0	COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria	57723|Acidobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WXD1_k127_3905190_3	1455608.JDTH01000002_gene1757	1.084e-130	434.0	COG0380@1|root,arCOG02831@2157|Archaea,2XSTE@28890|Euryarchaeota,23TQX@183963|Halobacteria	183963|Halobacteria	G	COG0380 Trehalose-6-phosphate synthase	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
WXD1_k127_3905190_1	404589.Anae109_0662	5.626e-143	470.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WXD1_k127_3905190_12	1158607.UAU_02774	1.053e-05	49.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,4IBNI@91061|Bacilli,4B3MY@81852|Enterococcaceae	91061|Bacilli	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
WXD1_k127_3905190_0	379066.GAU_0644	1.279e-172	567.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WXD1_k127_3905190_7	1123367.C666_02320	2.471e-62	225.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KVHM@206389|Rhodocyclales	206389|Rhodocyclales	G	COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WXD1_k127_3905190_4	1321786.HMPREF1992_02131	1.361e-89	304.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H2BR@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WXD1_k127_3905190_8	1244869.H261_08363	1.904e-58	224.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,2JPX3@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
WXD1_k127_3905190_5	634956.Geoth_2874	4.804e-79	270.0	COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,1WEFG@129337|Geobacillus	91061|Bacilli	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate	dapH	-	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU14180	DapH_N,Hexapep
WXD1_k127_3905190_10	926692.AZYG01000007_gene1357	3.766e-33	137.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia,3WAS3@53433|Halanaerobiales	186801|Clostridia	S	PFAM MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	ACT,ACT_4,MgtC
WXD1_k127_3905190_2	861299.J421_2803	2.488e-138	449.0	COG2805@1|root,COG2805@2|Bacteria,1ZT2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WXD1_k127_3924321_2	379066.GAU_2186	1.447e-28	119.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WXD1_k127_3924321_0	379066.GAU_3080	3.644e-308	965.0	COG0577@1|root,COG0577@2|Bacteria,1ZUI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_3924321_1	1144275.COCOR_00464	1.994e-99	330.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX1A@29|Myxococcales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
WXD1_k127_394005_0	472759.Nhal_3397	4.557e-218	708.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1WWSC@135613|Chromatiales	135613|Chromatiales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WXD1_k127_394005_4	379066.GAU_2847	1.269e-40	164.0	2ARQH@1|root,31H1J@2|Bacteria,1ZUJU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
WXD1_k127_394005_6	665571.STHERM_c20790	3.637e-09	70.0	2BVQY@1|root,2ZWGY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_394005_5	861299.J421_1150	8.172e-28	113.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WXD1_k127_394005_3	479434.Sthe_0894	6.715e-42	177.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,27Z1J@189775|Thermomicrobia	189775|Thermomicrobia	M	Tetratricopeptide repeat	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16
WXD1_k127_394005_1	861299.J421_1148	6.168e-65	241.0	2DTII@1|root,33KI8@2|Bacteria,1ZT3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_394005_2	459349.CLOAM0608	5.18e-45	172.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
WXD1_k127_3964991_0	861299.J421_6152	0.0	1452.0	COG3459@1|root,COG3459@2|Bacteria,1ZTGS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
WXD1_k127_3970907_5	373903.Hore_01670	9.763e-45	172.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WA96@53433|Halanaerobiales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
WXD1_k127_3970907_9	861299.J421_3007	9.847e-30	118.0	2EQ8R@1|root,33HV0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3970907_7	1379270.AUXF01000005_gene601	1.022e-30	127.0	2E5IJ@1|root,3309Y@2|Bacteria,1ZTU3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_3970907_1	379066.GAU_1295	3.274e-159	514.0	COG0112@1|root,COG0112@2|Bacteria,1ZT5K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WXD1_k127_3970907_2	861299.J421_3004	3.376e-146	488.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WXD1_k127_3970907_4	379066.GAU_1292	1.887e-73	260.0	COG1960@1|root,COG1960@2|Bacteria,1ZSRC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WXD1_k127_3970907_3	861299.J421_3002	3.114e-116	380.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WXD1_k127_3970907_8	861299.J421_3001	1.275e-30	132.0	COG1266@1|root,COG1266@2|Bacteria,1ZTXV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WXD1_k127_3970907_6	1042877.GQS_10615	5.153e-34	138.0	COG1268@1|root,arCOG02986@2157|Archaea,2XWSG@28890|Euryarchaeota,2447E@183968|Thermococci	183968|Thermococci	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
WXD1_k127_3970907_0	861299.J421_3000	5.039e-161	516.0	COG0183@1|root,COG0183@2|Bacteria,1ZTGX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WXD1_k127_39830_1	379066.GAU_0654	3.622e-115	390.0	COG1432@1|root,COG1432@2|Bacteria,1ZSRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
WXD1_k127_39830_0	861299.J421_2604	3.89e-178	573.0	COG0318@1|root,COG0318@2|Bacteria,1ZSXP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WXD1_k127_39830_2	861299.J421_2532	1.907e-92	319.0	COG0337@1|root,COG0337@2|Bacteria,1ZSS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
WXD1_k127_39830_3	306281.AJLK01000167_gene3840	1.54e-68	250.0	COG2170@1|root,COG2170@2|Bacteria,1G6F1@1117|Cyanobacteria	1117|Cyanobacteria	S	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
WXD1_k127_4002387_3	861299.J421_0639	2.686e-33	134.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WXD1_k127_4002387_0	861299.J421_2272	3.443e-157	531.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_4002387_1	1121403.AUCV01000018_gene3198	3.297e-61	238.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2WQM8@28221|Deltaproteobacteria,2MKXA@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	B_lectin,Inhibitor_I9,Peptidase_S8,Somatomedin_B
WXD1_k127_4002387_2	1379270.AUXF01000002_gene1323	4.125e-36	158.0	COG3170@1|root,COG3291@1|root,COG3170@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBM_6,GSDH,He_PIG,Malectin,PKD,Secretin,T2SS-T3SS_pil_N,VCBS,fn3
WXD1_k127_4002387_7	1123504.JQKD01000040_gene2779	0.0004434	51.0	COG4319@1|root,COG4319@2|Bacteria,1RGSM@1224|Proteobacteria,2VYTU@28216|Betaproteobacteria,4AG0E@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
WXD1_k127_4002387_4	861299.J421_1517	2.361e-26	111.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4006771_1	379066.GAU_0159	2.558e-120	398.0	COG4992@1|root,COG4992@2|Bacteria,1ZTEJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WXD1_k127_4006771_2	1128421.JAGA01000003_gene3445	4.313e-31	140.0	COG1246@1|root,COG1246@2|Bacteria,2NRHE@2323|unclassified Bacteria	2|Bacteria	E	Acetyltransferase (GNAT) domain	argH	GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,4.3.2.1	ko:K00619,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	M00028,M00029,M00844	R00259,R01086	RC00004,RC00064,RC00445,RC00447	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C2,Acetyltransf_1,Lyase_1
WXD1_k127_4006771_0	861299.J421_1323	8.11e-157	516.0	COG0137@1|root,COG0137@2|Bacteria,1ZTYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
WXD1_k127_4025037_5	861299.J421_2368	8.89e-46	179.0	2EXE5@1|root,33QQP@2|Bacteria,1ZTI3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4025037_9	379066.GAU_0464	2.44e-17	94.0	2FK9E@1|root,34BX2@2|Bacteria,1ZTYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4025037_1	316274.Haur_1203	3.85e-106	357.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	200795|Chloroflexi	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WXD1_k127_4025037_7	1385515.N791_06610	5.414e-38	148.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria,1X5FK@135614|Xanthomonadales	135614|Xanthomonadales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WXD1_k127_4025037_4	292459.STH1330	2.904e-49	179.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
WXD1_k127_4025037_8	177437.HRM2_21590	3.641e-28	118.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,42PGE@68525|delta/epsilon subdivisions,2WQTM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	Amino-transferase class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
WXD1_k127_4025037_6	1125863.JAFN01000001_gene457	7.177e-44	178.0	COG1624@1|root,COG1624@2|Bacteria,1N12B@1224|Proteobacteria,42UVR@68525|delta/epsilon subdivisions,2WQ2R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
WXD1_k127_4025037_3	1210908.HSB1_04500	1.289e-63	232.0	COG0434@1|root,arCOG01982@2157|Archaea,2XT9I@28890|Euryarchaeota,23T8W@183963|Halobacteria	183963|Halobacteria	S	photosystem I assembly BtpA	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
WXD1_k127_4025037_0	861299.J421_4207	5.688e-225	746.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_4025037_2	379066.GAU_0816	4.852e-87	295.0	COG1024@1|root,COG1024@2|Bacteria,1ZT76@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
WXD1_k127_402875_1	1519464.HY22_05180	9.64e-106	351.0	COG1131@1|root,COG1131@2|Bacteria,1FF0I@1090|Chlorobi	1090|Chlorobi	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_402875_6	1519464.HY22_08895	1.39e-12	80.0	COG1277@1|root,COG1277@2|Bacteria,1FFEA@1090|Chlorobi	1090|Chlorobi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
WXD1_k127_402875_0	1254432.SCE1572_22435	2.596e-126	421.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,42RYP@68525|delta/epsilon subdivisions,2WNDE@28221|Deltaproteobacteria,2YYGQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.99	ko:K19176	-	-	-	-	ko00000,ko01000	-	-	-	Amidase
WXD1_k127_402875_5	644282.Deba_0596	1.031e-62	231.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lytic transglycosylase catalytic	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
WXD1_k127_402875_3	861299.J421_3849	2.063e-85	304.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WXD1_k127_402875_4	1121104.AQXH01000005_gene248	2.569e-75	271.0	2CESB@1|root,2Z8UZ@2|Bacteria,4NJSJ@976|Bacteroidetes,1IVD7@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
WXD1_k127_402875_2	1219049.SP5_097_00610	4.825e-105	347.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2U0A3@28211|Alphaproteobacteria,2K5YI@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_4029123_1	468059.AUHA01000002_gene531	2.649e-68	240.0	29Z06@1|root,30KX7@2|Bacteria,4NZNI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
WXD1_k127_4029123_0	1379270.AUXF01000001_gene2237	9.646e-108	369.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	ko:K01446	-	-	R04112	RC00064,RC00141	ko00000	-	-	-	Amidase_2
WXD1_k127_4029123_2	929556.Solca_0067	6.678e-46	182.0	COG0741@1|root,COG1649@1|root,COG3023@1|root,COG0741@2|Bacteria,COG1649@2|Bacteria,COG3023@2|Bacteria,4NFKQ@976|Bacteroidetes,1IQ63@117747|Sphingobacteriia	976|Bacteroidetes	F	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
WXD1_k127_4029123_3	497964.CfE428DRAFT_0944	2.36e-16	83.0	COG4258@1|root,COG4258@2|Bacteria,46TC6@74201|Verrucomicrobia	2|Bacteria	S	MMPL family	hpnN	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
WXD1_k127_4032845_4	216432.CA2559_05100	9.078e-06	57.0	COG0366@1|root,COG0366@2|Bacteria,4NGC8@976|Bacteroidetes,1HWR1@117743|Flavobacteriia	976|Bacteroidetes	G	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase
WXD1_k127_4032845_2	861299.J421_4540	1.873e-16	88.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
WXD1_k127_4032845_3	319225.Plut_1980	2.791e-12	74.0	COG2010@1|root,COG2010@2|Bacteria,1FF39@1090|Chlorobi	1090|Chlorobi	C	PFAM cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
WXD1_k127_4032845_0	1122621.ATZA01000009_gene311	1.621e-192	635.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,1IP91@117747|Sphingobacteriia	976|Bacteroidetes	P	TonB-linked outer membrane protein, SusC RagA family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_4032845_1	1166018.FAES_1174	9.385e-49	192.0	2BX9T@1|root,2Z83P@2|Bacteria,4NFAA@976|Bacteroidetes,47M07@768503|Cytophagia	976|Bacteroidetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
WXD1_k127_4055903_3	246197.MXAN_5564	3.569e-05	48.0	COG5544@1|root,COG5544@2|Bacteria,1PD2E@1224|Proteobacteria,435E0@68525|delta/epsilon subdivisions,2WZRI@28221|Deltaproteobacteria,2Z2KM@29|Myxococcales	28221|Deltaproteobacteria	S	Lipoprotein	-	-	-	ko:K05811	-	-	-	-	ko00000	-	-	-	-
WXD1_k127_4055903_1	1089550.ATTH01000001_gene298	8.523e-90	315.0	COG2008@1|root,COG2008@2|Bacteria,4NEIH@976|Bacteroidetes,1FIQX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WXD1_k127_4055903_2	861299.J421_1405	5.804e-14	84.0	2A4E9@1|root,2ZJRI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4055903_0	861299.J421_0464	5.734e-141	468.0	COG0793@1|root,COG0793@2|Bacteria,1ZT92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WXD1_k127_4064547_1	768706.Desor_4658	2.432e-51	189.0	COG2318@1|root,COG2318@2|Bacteria,1V8MI@1239|Firmicutes	1239|Firmicutes	S	PFAM DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
WXD1_k127_4064547_0	471854.Dfer_4865	6.008e-71	260.0	COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes,47TM3@768503|Cytophagia	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4064547_2	1121920.AUAU01000005_gene1020	1.175e-15	76.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4076320_1	404589.Anae109_2645	2.901e-45	179.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	28221|Deltaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
WXD1_k127_4076320_0	404589.Anae109_2645	2.854e-101	361.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	28221|Deltaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
WXD1_k127_4076320_3	880073.Calab_3335	1.436e-06	53.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
WXD1_k127_4076320_2	1408473.JHXO01000005_gene1870	2.813e-33	139.0	COG0492@1|root,COG0492@2|Bacteria,4NNAA@976|Bacteroidetes,2FXF6@200643|Bacteroidia	976|Bacteroidetes	O	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4080537_2	234267.Acid_0469	8.417e-72	258.0	COG1506@1|root,COG1506@2|Bacteria,3Y3DT@57723|Acidobacteria	57723|Acidobacteria	E	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
WXD1_k127_4080537_1	251221.35212957	1.12e-88	319.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,TPR_16
WXD1_k127_4080537_3	861299.J421_4391	4.067e-54	201.0	COG1376@1|root,COG1376@2|Bacteria,1ZUZG@142182|Gemmatimonadetes	2|Bacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,YkuD
WXD1_k127_4080537_4	861299.J421_4391	1.227e-46	181.0	COG1376@1|root,COG1376@2|Bacteria,1ZUZG@142182|Gemmatimonadetes	2|Bacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1,YkuD
WXD1_k127_4080537_0	379066.GAU_2758	6.305e-124	404.0	COG0761@1|root,COG0761@2|Bacteria,1ZTGU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
WXD1_k127_4114624_5	234267.Acid_3076	1.015e-09	62.0	COG2091@1|root,COG2091@2|Bacteria,3Y8HB@57723|Acidobacteria	57723|Acidobacteria	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WXD1_k127_4114624_1	1379698.RBG1_1C00001G0813	6.288e-104	347.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
WXD1_k127_4114624_2	502025.Hoch_3922	1.759e-73	264.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,42V9E@68525|delta/epsilon subdivisions,2WRIJ@28221|Deltaproteobacteria,2Z0W1@29|Myxococcales	28221|Deltaproteobacteria	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WXD1_k127_4114624_0	1307436.PBF_24034	8.171e-157	514.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4HA2Y@91061|Bacilli,1ZAV3@1386|Bacillus	91061|Bacilli	E	Catalyzes the interconversion of ornithine to glutamate semialdehyde	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009064,GO:0009987,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901605	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
WXD1_k127_4114624_4	383372.Rcas_4353	3.337e-35	141.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377DT@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WXD1_k127_4114624_3	1114959.SZMC14600_16301	2.989e-60	223.0	COG3023@1|root,COG3023@2|Bacteria,2HVMQ@201174|Actinobacteria	201174|Actinobacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4129181_1	861299.J421_2962	8.726e-122	427.0	COG4191@1|root,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
WXD1_k127_4129181_2	861299.J421_0233	3.303e-66	241.0	COG3434@1|root,COG3434@2|Bacteria,1ZTD8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
WXD1_k127_4129181_3	316057.RPD_3277	1.117e-20	107.0	COG3829@1|root,COG3852@1|root,COG3829@2|Bacteria,COG3852@2|Bacteria,1QW3X@1224|Proteobacteria,2TY09@28211|Alphaproteobacteria,3K6VB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
WXD1_k127_4129181_0	861299.J421_0161	2.51e-148	490.0	COG0643@1|root,COG0643@2|Bacteria,1ZTCI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
WXD1_k127_4131822_2	644282.Deba_1222	5.202e-94	316.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WXD1_k127_4131822_0	1192034.CAP_5365	1.044e-137	448.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42MSR@68525|delta/epsilon subdivisions,2WIXG@28221|Deltaproteobacteria,2Z30V@29|Myxococcales	28221|Deltaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WXD1_k127_4131822_1	342949.PNA2_1341	2.616e-106	355.0	COG0473@1|root,arCOG01163@2157|Archaea,2XT99@28890|Euryarchaeota,242YH@183968|Thermococci	183968|Thermococci	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WXD1_k127_4131822_3	1379270.AUXF01000002_gene1410	5.504e-06	54.0	COG3794@1|root,COG3794@2|Bacteria,1ZTTE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	ko:K02638	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Copper-bind
WXD1_k127_4133300_0	926569.ANT_29930	1.6e-105	361.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
WXD1_k127_4133300_1	1227739.Hsw_2747	1.865e-51	194.0	COG2318@1|root,COG2318@2|Bacteria,4NNQI@976|Bacteroidetes,47QCG@768503|Cytophagia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_4167331_3	404589.Anae109_3522	4.344e-91	306.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42S59@68525|delta/epsilon subdivisions,2WNGW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hybA	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
WXD1_k127_4167331_2	404589.Anae109_3521	9.789e-96	331.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
WXD1_k127_4167331_0	1167006.UWK_01157	2.487e-270	842.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria,2MI12@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hynA	-	1.12.2.1,1.12.5.1,1.12.99.6	ko:K00437,ko:K05922,ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WXD1_k127_4167331_5	404589.Anae109_0522	2.545e-43	173.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
WXD1_k127_4167331_6	1291050.JAGE01000001_gene1516	7.519e-18	90.0	COG0375@1|root,COG0375@2|Bacteria,1VEP0@1239|Firmicutes,24RHI@186801|Clostridia	186801|Clostridia	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
WXD1_k127_4167331_4	398512.JQKC01000038_gene4571	2.583e-66	232.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3WJR9@541000|Ruminococcaceae	186801|Clostridia	KO	TIGRFAM hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
WXD1_k127_4167331_1	926550.CLDAP_07460	1.74e-247	788.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
WXD1_k127_4200103_2	483219.LILAB_10680	6.954e-108	354.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU6E@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_4200103_0	1267535.KB906767_gene628	2.155e-157	509.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria,2JHXU@204432|Acidobacteriia	204432|Acidobacteriia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
WXD1_k127_4200103_5	861299.J421_4375	3.764e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_4200103_6	1123256.KB907944_gene423	1.809e-25	117.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WXD1_k127_4200103_8	861299.J421_5670	3.5e-23	112.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5670|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4200103_4	313606.M23134_01223	7.984e-59	227.0	COG3034@1|root,COG3034@2|Bacteria,4NNK3@976|Bacteroidetes,47PW3@768503|Cytophagia	976|Bacteroidetes	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C,YkuD
WXD1_k127_4200103_1	195253.Syn6312_0679	8.527e-124	425.0	COG1716@1|root,COG2202@1|root,COG5001@1|root,COG1716@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1GYX2@1129|Synechococcus	1117|Cyanobacteria	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FHA,GGDEF,PAS,PAS_3
WXD1_k127_4200103_3	67315.JOBD01000027_gene2379	2.262e-73	260.0	COG4447@1|root,COG4447@2|Bacteria,2GMJN@201174|Actinobacteria	201174|Actinobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
WXD1_k127_4200103_7	1382356.JQMP01000001_gene797	1.371e-24	108.0	COG1959@1|root,COG1959@2|Bacteria	2|Bacteria	K	2 iron, 2 sulfur cluster binding	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
WXD1_k127_4213826_2	575540.Isop_1665	5.947e-31	131.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
WXD1_k127_4213826_0	575540.Isop_1666	2.865e-90	319.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
WXD1_k127_4213826_4	925409.KI911562_gene2744	4.525e-06	59.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,4NEJX@976|Bacteroidetes	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,TPR_12,TPR_7,TPR_8
WXD1_k127_4213826_5	526227.Mesil_3342	1.554e-05	55.0	2DVHC@1|root,33VWJ@2|Bacteria,1WMN4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4213826_1	573370.DMR_19630	5.899e-76	271.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_4213826_3	1121930.AQXG01000001_gene1453	2.653e-12	77.0	COG4726@1|root,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K02673	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	DUF4900,PilX_N
WXD1_k127_4234808_5	292459.STH749	2.476e-38	161.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
WXD1_k127_4234808_7	880072.Desac_0830	2.491e-18	90.0	COG0745@1|root,COG0745@2|Bacteria,1PGXZ@1224|Proteobacteria,437JJ@68525|delta/epsilon subdivisions,2X2TK@28221|Deltaproteobacteria,2MSE0@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WXD1_k127_4234808_3	269796.Rru_A0321	2.777e-65	232.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2UDQI@28211|Alphaproteobacteria,2JXAG@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
WXD1_k127_4234808_1	269796.Rru_A0320	1.002e-102	358.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2UQND@28211|Alphaproteobacteria,2JZPC@204441|Rhodospirillales	204441|Rhodospirillales	C	Proton-conducting membrane transporter	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WXD1_k127_4234808_4	269796.Rru_A0319	2.46e-42	164.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2UHD9@28211|Alphaproteobacteria,2JXQX@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q2
WXD1_k127_4234808_6	338966.Ppro_2784	4.579e-37	145.0	COG1143@1|root,COG1143@2|Bacteria,1R9YT@1224|Proteobacteria,42P0W@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hyfH	-	-	ko:K12143,ko:K15831	-	-	-	-	ko00000	-	-	iAPECO1_1312.APECO1_3805,iECABU_c1320.ECABU_c29910,iECED1_1282.ECED1_3171,iECOK1_1307.ECOK1_3094,iUMN146_1321.UM146_02980,iUTI89_1310.UTI89_C3083,ic_1306.c3280	Fer4,Fer4_7
WXD1_k127_4234808_2	269796.Rru_A0317	2.383e-69	245.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2UD34@28211|Alphaproteobacteria,2JX3S@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
WXD1_k127_4234808_0	269796.Rru_A0316	7.441e-182	593.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,2U3G9@28211|Alphaproteobacteria,2JVR1@204441|Rhodospirillales	204441|Rhodospirillales	C	Nickel-dependent hydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
WXD1_k127_4234808_8	269796.Rru_A0315	5.101e-13	76.0	COG1009@1|root,COG1009@2|Bacteria,1QV11@1224|Proteobacteria	1224|Proteobacteria	C	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
WXD1_k127_4243966_0	1278073.MYSTI_05670	1.171e-96	325.0	COG2303@1|root,COG2303@2|Bacteria,1NV3A@1224|Proteobacteria,42NVR@68525|delta/epsilon subdivisions,2WM9A@28221|Deltaproteobacteria,2YU0T@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
WXD1_k127_4243966_3	1201288.M900_1269	5.104e-05	51.0	COG3197@1|root,COG3197@2|Bacteria,1PUQX@1224|Proteobacteria,433SW@68525|delta/epsilon subdivisions,2WYFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	cytochrome oxidase maturation protein cbb3-type	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
WXD1_k127_4243966_1	272568.GDI3132	1.652e-50	191.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2JPCQ@204441|Rhodospirillales	204441|Rhodospirillales	P	COG2217 Cation transport ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WXD1_k127_4246779_2	264462.Bd2310	7.234e-127	424.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2MT1N@213481|Bdellovibrionales,2WJPF@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WXD1_k127_4246779_0	379066.GAU_1598	4.317e-196	629.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
WXD1_k127_4246779_1	1121468.AUBR01000007_gene252	1.038e-128	431.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WXD1_k127_4246779_3	243231.GSU0141	2.094e-77	275.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,43U9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
WXD1_k127_4246779_4	426117.M446_0702	7.411e-07	62.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,1JSAA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
WXD1_k127_4247386_0	861299.J421_0935	2.49e-174	565.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg
WXD1_k127_4252430_4	710696.Intca_3462	3.027e-22	103.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
WXD1_k127_4252430_3	457415.HMPREF1006_01013	4.19e-31	135.0	COG1917@1|root,COG1917@2|Bacteria,3TBF3@508458|Synergistetes	508458|Synergistetes	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4252430_5	861299.J421_1004	1.079e-18	98.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WXD1_k127_4252430_0	1273538.G159_09040	4.055e-86	294.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli,26H00@186818|Planococcaceae	91061|Bacilli	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
WXD1_k127_4252430_2	861299.J421_2069	2.821e-41	164.0	COG0234@1|root,COG0234@2|Bacteria,1ZU6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
WXD1_k127_4252430_1	1283299.AUKG01000001_gene1520	4.284e-57	207.0	COG1960@1|root,COG1960@2|Bacteria,2GKK9@201174|Actinobacteria,4CPTN@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WXD1_k127_4254480_12	1123057.P872_18540	3.406e-27	121.0	COG3121@1|root,COG3121@2|Bacteria,4PAU2@976|Bacteroidetes,47UHZ@768503|Cytophagia	976|Bacteroidetes	NU	Chaperone	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4254480_13	1250278.JQNQ01000001_gene29	1.84e-21	111.0	COG3188@1|root,COG3188@2|Bacteria,4NFPY@976|Bacteroidetes,1HXS8@117743|Flavobacteriia	976|Bacteroidetes	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4254480_6	1379270.AUXF01000003_gene3371	3.457e-62	221.0	COG0745@1|root,COG0745@2|Bacteria,1ZUZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WXD1_k127_4254480_11	1038859.AXAU01000015_gene933	4.996e-35	139.0	2DJKR@1|root,32YT5@2|Bacteria,1NACC@1224|Proteobacteria,2UDCH@28211|Alphaproteobacteria,3K0FK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4254480_8	931277.C448_10537	5.946e-43	171.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y8D0@28890|Euryarchaeota,23S38@183963|Halobacteria	183963|Halobacteria	S	Fe-S oxidoreductases	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
WXD1_k127_4254480_14	671143.DAMO_1688	2.167e-19	102.0	COG3278@1|root,COG3278@2|Bacteria,2NRHY@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4254480_2	861299.J421_4425	9.229e-81	286.0	COG4826@1|root,COG4826@2|Bacteria,1ZTM3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
WXD1_k127_4254480_5	379066.GAU_0039	3.297e-65	247.0	COG3391@1|root,COG3391@2|Bacteria,1ZU68@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4254480_7	861299.J421_5909	4.961e-51	205.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5909|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4254480_3	518766.Rmar_2036	8.012e-78	269.0	COG1028@1|root,COG1028@2|Bacteria,4NGR3@976|Bacteroidetes,1FIP0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
WXD1_k127_4254480_16	1122915.AUGY01000019_gene6313	0.0002413	52.0	2CKD9@1|root,333BQ@2|Bacteria,1VIGZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4254480_15	1177154.Y5S_00479	2.478e-13	79.0	294RE@1|root,2ZS4P@2|Bacteria,1P9TN@1224|Proteobacteria,1SV2K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4254480_10	861299.J421_6213	2.622e-35	136.0	COG5470@1|root,COG5470@2|Bacteria,1ZU5S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
WXD1_k127_4254480_0	483219.LILAB_10385	5.148e-142	465.0	COG2304@1|root,COG2304@2|Bacteria,1R8EZ@1224|Proteobacteria,433AE@68525|delta/epsilon subdivisions,2WYFQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
WXD1_k127_4254480_9	1121377.KB906416_gene4013	1.357e-36	140.0	COG0221@1|root,COG0221@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
WXD1_k127_4254480_4	1047013.AQSP01000098_gene2571	2.882e-69	252.0	COG3579@1|root,COG3579@2|Bacteria	2|Bacteria	E	homocysteine catabolic process	-	-	3.4.22.40	ko:K01372,ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03032	-	-	-	Peptidase_C1,Peptidase_C1_2
WXD1_k127_4254480_1	1120705.FG95_00881	1.097e-93	321.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TQRF@28211|Alphaproteobacteria,2KD3V@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_4256365_5	882082.SaccyDRAFT_2887	1.547e-07	60.0	COG2197@1|root,COG2197@2|Bacteria,2IATK@201174|Actinobacteria,4E4QW@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WXD1_k127_4256365_3	861299.J421_6034	2.399e-42	179.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,Guanylate_cyc,Trans_reg_C
WXD1_k127_4256365_2	1123508.JH636445_gene6557	7.038e-51	189.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_4256365_0	1210884.HG799469_gene14157	2.46e-282	888.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
WXD1_k127_4256365_1	1123368.AUIS01000001_gene1942	5.331e-101	337.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,1RMF8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	zinc metallopeptidase	ypfJ	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
WXD1_k127_4256365_4	1049564.TevJSym_at00550	1.076e-31	132.0	COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,1RMN7@1236|Gammaproteobacteria,1J69D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Fe-S protein	ycbX	GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754	-	ko:K07140	-	-	-	-	ko00000	-	-	-	FAD_binding_6,Fer2,MOSC,MOSC_N,NAD_binding_1
WXD1_k127_4258311_26	525898.Sdel_1436	5.233e-11	70.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,42Q7N@68525|delta/epsilon subdivisions,2YMDA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4258311_8	937777.Deipe_1817	6.567e-142	456.0	COG0346@1|root,COG0346@2|Bacteria,1WICF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
WXD1_k127_4258311_15	709986.Deima_1742	8.65e-102	340.0	COG0346@1|root,COG0346@2|Bacteria,1WICF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
WXD1_k127_4258311_17	861299.J421_1420	1.219e-49	186.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	SLH,YkuD
WXD1_k127_4258311_12	749222.Nitsa_1080	5.205e-112	390.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2YN2Q@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	L	Mitochondrial degradasome RNA helicase subunit C terminal	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C,SUV3_C
WXD1_k127_4258311_24	435590.BVU_2545	4.228e-14	82.0	29A5Q@1|root,2ZX6Q@2|Bacteria,4NP43@976|Bacteroidetes,2FPGZ@200643|Bacteroidia,4AKRU@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG26960 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4258311_22	926554.KI912672_gene75	3.025e-25	113.0	COG1846@1|root,COG1846@2|Bacteria,1WMU3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WXD1_k127_4258311_10	713586.KB900536_gene2395	3.09e-125	408.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,1S93R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
WXD1_k127_4258311_14	518766.Rmar_0250	2.5e-110	372.0	COG0111@1|root,COG0111@2|Bacteria,4NGEB@976|Bacteroidetes,1FIM2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	-	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
WXD1_k127_4258311_4	379066.GAU_2911	1.277e-217	711.0	COG5276@1|root,COG5276@2|Bacteria,1ZSZX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4258311_21	861299.J421_2208	4.618e-35	143.0	COG3544@1|root,COG3544@2|Bacteria,1ZTVJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
WXD1_k127_4258311_1	1219049.SP5_009_00010	2.086e-296	930.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria,2JZUM@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
WXD1_k127_4258311_11	926549.KI421517_gene1814	3.581e-120	403.0	COG3458@1|root,COG3458@2|Bacteria,4NGH5@976|Bacteroidetes,47MHG@768503|Cytophagia	976|Bacteroidetes	Q	PFAM Acetyl xylan esterase	axe7A_2	-	-	-	-	-	-	-	-	-	-	-	AXE1
WXD1_k127_4258311_16	1191523.MROS_0929	1.654e-52	203.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Imp-YgjV
WXD1_k127_4258311_13	861299.J421_1003	2.804e-111	387.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WXD1_k127_4258311_3	290397.Adeh_2029	1.899e-236	747.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2WJNB@28221|Deltaproteobacteria,2YU00@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WXD1_k127_4258311_7	861299.J421_4340	4.384e-167	538.0	COG0520@1|root,COG0520@2|Bacteria,1ZSV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_4258311_0	761193.Runsl_1070	0.0	1342.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,47NFD@768503|Cytophagia	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
WXD1_k127_4258311_2	398767.Glov_2615	1.422e-293	907.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,43DIW@68525|delta/epsilon subdivisions,2X8Q7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
WXD1_k127_4258311_9	880072.Desac_2769	5.606e-131	436.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2MQ8M@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	-	-	4.4.1.11,4.4.1.8	ko:K01760,ko:K01761	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00654,R00782,R01286,R02408,R04770,R04941	RC00056,RC00069,RC00196,RC00348,RC00382,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WXD1_k127_4258311_18	234267.Acid_7677	3.127e-49	189.0	COG1595@1|root,COG1595@2|Bacteria,3Y7UW@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
WXD1_k127_4258311_6	861299.J421_0624	3.452e-179	593.0	COG0515@1|root,COG0515@2|Bacteria,1ZUHA@142182|Gemmatimonadetes	861299.J421_0624|-	KLT	Tetratricopeptide repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WXD1_k127_4258311_5	861299.J421_4119	2.178e-191	609.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WXD1_k127_4258311_23	452637.Oter_0366	1.05e-15	90.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WXD1_k127_4258311_25	439235.Dalk_2427	9.335e-12	77.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	adiA	-	2.7.7.65,4.1.1.19	ko:K01584,ko:K20955	ko00330,ko01100,ko05111,map00330,map01100,map05111	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GGDEF,HATPase_c,HisKA,NB-ARC,OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N,Response_reg,TPR_12,dCache_1
WXD1_k127_4258311_27	1382306.JNIM01000001_gene1291	5.904e-06	56.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368,ko:K02638	ko00195,ko00910,ko01120,map00195,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	CHRD,Copper-bind,Cu-oxidase_3,Cupredoxin_1
WXD1_k127_4258311_20	945713.IALB_2753	1.096e-36	153.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TPR_11,TPR_16,TPR_8,Trypsin_2
WXD1_k127_4258311_28	1047013.AQSP01000142_gene196	1.119e-05	52.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4258311_19	861299.J421_5740	9.29e-49	194.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5740|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4259339_2	861299.J421_2559	4.895e-31	131.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WXD1_k127_4259339_5	1379270.AUXF01000004_gene3137	5.109e-10	72.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	ligA1	-	-	-	-	-	-	-	-	-	-	-	Big_2
WXD1_k127_4259339_1	550540.Fbal_3278	8.478e-32	137.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WXD1_k127_4259339_0	861299.J421_0445	1.358e-39	151.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0035821,GO:0036293,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052564,GO:0052572,GO:0070482,GO:0071944,GO:0075136	-	-	-	-	-	-	-	-	-	-	CBS
WXD1_k127_4259339_4	314287.GB2207_11628	8.809e-14	74.0	2DMTH@1|root,32TKP@2|Bacteria,1N4TE@1224|Proteobacteria,1S9K6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4259339_3	1196323.ALKF01000196_gene2115	5.01e-31	138.0	COG1409@1|root,COG4632@1|root,COG1409@2|Bacteria,COG4632@2|Bacteria,1UIPK@1239|Firmicutes,4ISP6@91061|Bacilli,2775H@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Metallophos,NAGPA,Pur_ac_phosph_N,SLH
WXD1_k127_4272212_5	1379270.AUXF01000004_gene3177	4.216e-64	237.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WXD1_k127_4272212_6	1379698.RBG1_1C00001G0978	6.639e-43	170.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WXD1_k127_4272212_7	1499967.BAYZ01000194_gene3125	1.394e-35	143.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WXD1_k127_4272212_8	861299.J421_0561	5.865e-29	125.0	2CDZB@1|root,3340J@2|Bacteria,1ZU24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4272212_4	215803.DB30_0807	5.864e-127	417.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,42PES@68525|delta/epsilon subdivisions,2WME8@28221|Deltaproteobacteria,2YWIV@29|Myxococcales	28221|Deltaproteobacteria	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
WXD1_k127_4272212_3	204773.HEAR3216	6.323e-136	443.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,475AE@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
WXD1_k127_4272212_9	1131269.AQVV01000011_gene2520	6.286e-25	111.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
WXD1_k127_4272212_0	1303518.CCALI_02547	0.0	1214.0	COG1048@1|root,COG1048@2|Bacteria	2|Bacteria	C	aconitate hydratase activity	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WXD1_k127_4272212_2	861299.J421_2577	1.168e-146	474.0	COG0436@1|root,COG0436@2|Bacteria,1ZT26@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
WXD1_k127_4272212_1	861299.J421_5982	8.713e-263	837.0	COG1629@1|root,COG1629@2|Bacteria,1ZV2K@142182|Gemmatimonadetes	2|Bacteria	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug
WXD1_k127_4298831_6	1121921.KB898710_gene506	9.847e-30	118.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,2PMNU@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	ABC transporter	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WXD1_k127_4298831_4	671143.DAMO_1099	2.119e-48	182.0	COG0704@1|root,COG1392@1|root,COG0704@2|Bacteria,COG1392@2|Bacteria,2NPPV@2323|unclassified Bacteria	2|Bacteria	P	Protein of unknown function DUF47	phoU	GO:0000287,GO:0001558,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006873,GO:0006950,GO:0007154,GO:0008150,GO:0009266,GO:0009267,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009628,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0016020,GO:0016036,GO:0019220,GO:0019222,GO:0019725,GO:0019897,GO:0019898,GO:0022898,GO:0030002,GO:0030145,GO:0030320,GO:0030643,GO:0031323,GO:0031324,GO:0031667,GO:0031668,GO:0031669,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032879,GO:0033554,GO:0034605,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0040008,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043269,GO:0043271,GO:0044070,GO:0044092,GO:0044419,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045936,GO:0046677,GO:0046872,GO:0046914,GO:0046983,GO:0048519,GO:0048523,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051049,GO:0051051,GO:0051128,GO:0051174,GO:0051704,GO:0051716,GO:0055062,GO:0055081,GO:0055082,GO:0055083,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071496,GO:0071944,GO:0072501,GO:0072502,GO:0072505,GO:0072506,GO:0098771,GO:0104004,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039,ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU,PhoU_div
WXD1_k127_4298831_2	1379698.RBG1_1C00001G0906	2.962e-61	222.0	COG1028@1|root,COG1028@2|Bacteria,2NP35@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WXD1_k127_4298831_1	1415780.JPOG01000001_gene1376	2.56e-130	425.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,1T1N6@1236|Gammaproteobacteria,1X358@135614|Xanthomonadales	135614|Xanthomonadales	CE	Catalyzes the formation of 2-oxoglutarate from isocitrate	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WXD1_k127_4298831_3	247156.NFA_37010	7.697e-59	209.0	COG3832@1|root,COG3832@2|Bacteria,2IFFI@201174|Actinobacteria,4G1C9@85025|Nocardiaceae	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WXD1_k127_4298831_5	1179773.BN6_64320	4.442e-34	134.0	COG0640@1|root,COG0640@2|Bacteria,2ISNZ@201174|Actinobacteria,4E5EH@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
WXD1_k127_4298831_0	379066.GAU_2471	1.25e-184	586.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WXD1_k127_4303430_6	697281.Mahau_1635	5.013e-54	192.0	COG0047@1|root,COG0047@2|Bacteria,1TP1B@1239|Firmicutes,24A2E@186801|Clostridia,42EVD@68295|Thermoanaerobacterales	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WXD1_k127_4303430_8	379066.GAU_1735	1.016e-21	98.0	COG1828@1|root,COG1828@2|Bacteria,1ZU3W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
WXD1_k127_4303430_4	1379270.AUXF01000006_gene156	9.113e-72	259.0	COG1183@1|root,COG1183@2|Bacteria,1ZTJP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
WXD1_k127_4303430_1	861299.J421_3374	1.281e-112	384.0	COG0152@1|root,COG0152@2|Bacteria,1ZT6T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WXD1_k127_4303430_0	887929.HMP0721_1189	7.08e-181	580.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,25V1Q@186806|Eubacteriaceae	186801|Clostridia	F	adenylosuccinate lyase	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WXD1_k127_4303430_2	379066.GAU_1730	3.445e-106	368.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WXD1_k127_4303430_3	1125863.JAFN01000001_gene2550	4.236e-83	281.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
WXD1_k127_4303430_5	861299.J421_3369	1.42e-68	245.0	COG0101@1|root,COG0101@2|Bacteria,1ZSRZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WXD1_k127_4303430_9	1499967.BAYZ01000172_gene5784	3.292e-08	60.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
WXD1_k127_4303430_7	352165.HMPREF7215_0530	4.417e-45	165.0	COG0156@1|root,COG0156@2|Bacteria,3TAG5@508458|Synergistetes	508458|Synergistetes	H	PFAM Aminotransferase class I and II	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WXD1_k127_4347093_3	1123060.JONP01000107_gene504	0.0004207	45.0	COG2963@1|root,COG2963@2|Bacteria,1RJ7G@1224|Proteobacteria,2VG36@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
WXD1_k127_4347093_1	1191523.MROS_1497	1.145e-115	389.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_4347093_0	1191523.MROS_1496	9.931e-162	525.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_4347093_2	391603.FBALC1_05263	4.943e-82	290.0	COG0451@1|root,COG0451@2|Bacteria,4NX6A@976|Bacteroidetes,1IAM7@117743|Flavobacteriia	976|Bacteroidetes	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WXD1_k127_4355734_1	62928.azo3792	5.977e-73	253.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,2VJ4W@28216|Betaproteobacteria,2KWD1@206389|Rhodocyclales	206389|Rhodocyclales	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WXD1_k127_4355734_2	62928.azo3789	6.148e-25	112.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2VU0Y@28216|Betaproteobacteria,2KXJ6@206389|Rhodocyclales	206389|Rhodocyclales	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WXD1_k127_4355734_0	1121033.AUCF01000014_gene1259	3.029e-82	279.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,2TSH2@28211|Alphaproteobacteria,2JR2X@204441|Rhodospirillales	204441|Rhodospirillales	C	Prokaryotic cytochrome b561	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
WXD1_k127_4355734_3	316057.RPD_1163	8.096e-16	76.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,2TSH1@28211|Alphaproteobacteria,3JR0F@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hupL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
WXD1_k127_4388163_1	204669.Acid345_2964	1.946e-189	599.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	57723|Acidobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WXD1_k127_4388163_0	204669.Acid345_2965	5.653e-258	818.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.33,4.2.1.35,4.2.1.36	ko:K01703,ko:K01704,ko:K01705	ko00290,ko00300,ko00660,ko00966,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00300,map00660,map00966,map01100,map01110,map01120,map01130,map01210,map01230	M00030,M00432,M00433,M00535	R03896,R03898,R03968,R04001,R04371,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WXD1_k127_4388163_2	204669.Acid345_2966	1.225e-51	187.0	COG2079@1|root,COG2079@2|Bacteria,3Y5N1@57723|Acidobacteria,2JK64@204432|Acidobacteriia	204432|Acidobacteriia	S	MmgE/PrpD family	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
WXD1_k127_4397443_0	861299.J421_0388	1.497e-145	518.0	2DC46@1|root,2ZCU7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4397443_4	1120936.KB907208_gene814	3.281e-08	65.0	COG1100@1|root,COG1100@2|Bacteria,2I8XN@201174|Actinobacteria,4EH73@85012|Streptosporangiales	201174|Actinobacteria	S	Small GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4397443_2	575590.HMPREF0156_01789	2.725e-17	81.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes	976|Bacteroidetes	D	SpoIID LytB domain protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
WXD1_k127_4402356_0	379066.GAU_1454	1.684e-146	477.0	COG0621@1|root,COG0621@2|Bacteria,1ZT0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WXD1_k127_4402356_2	861299.J421_3097	1.63e-19	102.0	2EYUI@1|root,33S1Q@2|Bacteria,1ZTHR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4402356_1	643648.Slip_1636	4.86e-37	143.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,42K0G@68298|Syntrophomonadaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
WXD1_k127_443961_4	489825.LYNGBM3L_51530	1.603e-87	308.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WXD1_k127_443961_5	1123360.thalar_02869	6.431e-36	143.0	29FX8@1|root,302UX@2|Bacteria,1RKA5@1224|Proteobacteria,2UH09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_443961_3	1133850.SHJG_8002	2.418e-97	339.0	2DBCN@1|root,2Z8EJ@2|Bacteria,2I6NC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_443961_1	626887.J057_16710	5.562e-129	430.0	COG2837@1|root,COG2837@2|Bacteria,1MXKF@1224|Proteobacteria,1S153@1236|Gammaproteobacteria,46B7I@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	Dyp_perox
WXD1_k127_443961_2	285535.JOEY01000028_gene7281	1.195e-126	428.0	COG2937@1|root,COG2937@2|Bacteria,2I3XZ@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the GPAT DAPAT family	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_443961_0	857087.Metme_1420	0.0	1172.0	COG2373@1|root,COG2373@2|Bacteria,1Q2SN@1224|Proteobacteria,1S1CA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
WXD1_k127_4440617_3	1192034.CAP_1621	1.683e-21	95.0	COG0119@1|root,COG2080@1|root,COG0119@2|Bacteria,COG2080@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YTZB@29|Myxococcales	28221|Deltaproteobacteria	E	synthase homocitrate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like
WXD1_k127_4440617_2	696281.Desru_0531	3.088e-29	128.0	COG2068@1|root,COG2068@2|Bacteria,1UY6E@1239|Firmicutes,249PV@186801|Clostridia,260Y2@186807|Peptococcaceae	186801|Clostridia	S	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,NTP_transf_3
WXD1_k127_4440617_1	463191.SSEG_10189	8.545e-38	155.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
WXD1_k127_4440617_4	1121090.KB894685_gene3540	5.171e-18	89.0	COG1975@1|root,COG1975@2|Bacteria,1VFRE@1239|Firmicutes,4IKUK@91061|Bacilli,1ZHNN@1386|Bacillus	91061|Bacilli	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
WXD1_k127_4440617_0	1313301.AUGC01000005_gene302	2.092e-102	349.0	COG0334@1|root,COG0334@2|Bacteria,4NG6Y@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WXD1_k127_4465467_0	269799.Gmet_1200	9.003e-309	1001.0	COG1075@1|root,COG4995@1|root,COG1075@2|Bacteria,COG4995@2|Bacteria,1MUIQ@1224|Proteobacteria,42XEE@68525|delta/epsilon subdivisions,2WT63@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,LCAT
WXD1_k127_4465467_1	861299.J421_1644	2.151e-67	238.0	2EU07@1|root,33MHA@2|Bacteria	2|Bacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
WXD1_k127_4465467_2	861299.J421_6160	1.038e-39	168.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_6160|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WXD1_k127_4497270_0	1128421.JAGA01000003_gene2923	4.114e-314	969.0	COG1053@1|root,COG1053@2|Bacteria,2NQMR@2323|unclassified Bacteria	2|Bacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WXD1_k127_4497270_1	861299.J421_3298	4.611e-115	377.0	COG0479@1|root,COG0479@2|Bacteria,1ZT02@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
WXD1_k127_4500572_0	1340493.JNIF01000004_gene21	1.522e-242	763.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria	57723|Acidobacteria	S	Penicillin amidase	-	-	-	-	-	-	-	-	-	-	-	-	Penicil_amidase
WXD1_k127_4500572_3	1379270.AUXF01000003_gene3655	3.893e-57	220.0	COG0460@1|root,COG2021@1|root,COG0460@2|Bacteria,COG2021@2|Bacteria,1ZU32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Homoserine_dh,NAD_binding_3
WXD1_k127_4500572_2	379066.GAU_2223	1.817e-82	287.0	COG0460@1|root,COG2021@1|root,COG0460@2|Bacteria,COG2021@2|Bacteria,1ZU32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Homoserine_dh,NAD_binding_3
WXD1_k127_4500572_1	379066.GAU_2222	1.956e-190	604.0	COG2873@1|root,COG2873@2|Bacteria,1ZUS4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
WXD1_k127_4500572_5	234267.Acid_1443	8.015e-49	201.0	COG1413@1|root,COG3202@1|root,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	HEAT_2,NB-ARC,TLC,cNMP_binding
WXD1_k127_4500572_10	234267.Acid_1444	3.096e-16	94.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	CP_0464	-	1.8.1.9	ko:K00384,ko:K01999,ko:K07001,ko:K10914	ko00450,ko02010,ko02020,ko02024,ko02025,ko02026,ko05111,map00450,map02010,map02020,map02024,map02025,map02026,map05111	M00237	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	3.A.1.4	-	-	HTH_Crp_2,cNMP_binding
WXD1_k127_4500572_7	234267.Acid_1446	1.028e-38	152.0	COG3437@1|root,COG3437@2|Bacteria,3Y907@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
WXD1_k127_4500572_4	29581.BW37_01460	1.298e-49	193.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,476K9@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	PAS fold	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_9
WXD1_k127_4500572_6	1122179.KB890446_gene386	4.942e-45	179.0	COG0639@1|root,COG0639@2|Bacteria,4NME8@976|Bacteroidetes,1IS77@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WXD1_k127_4500572_9	479431.Namu_0361	2.64e-19	94.0	COG1765@1|root,COG1765@2|Bacteria,2IFY4@201174|Actinobacteria,4ET1W@85013|Frankiales	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
WXD1_k127_4500572_11	219305.MCAG_01202	6.826e-06	56.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,4DD40@85008|Micromonosporales	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WXD1_k127_4500572_8	861299.J421_0388	4.088e-30	129.0	2DC46@1|root,2ZCU7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4502416_0	861299.J421_3780	0.0	1175.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WXD1_k127_4502416_1	479432.Sros_4268	6.468e-109	364.0	COG0520@1|root,COG0520@2|Bacteria,2H9MG@201174|Actinobacteria,4EHWB@85012|Streptosporangiales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_4502416_3	404589.Anae109_2403	3.168e-77	271.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,42N26@68525|delta/epsilon subdivisions,2WK9Q@28221|Deltaproteobacteria,2Z34B@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
WXD1_k127_4502416_2	861299.J421_1274	7.101e-105	350.0	COG0040@1|root,COG0040@2|Bacteria,1ZSZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
WXD1_k127_4502416_4	1121015.N789_04195	2.57e-07	59.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1X4GX@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
WXD1_k127_4510287_2	443143.GM18_0007	1.412e-97	327.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WXD1_k127_4510287_3	861299.J421_3236	8.868e-42	172.0	COG0344@1|root,COG0344@2|Bacteria,1ZTTW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WXD1_k127_4510287_0	562970.Btus_1769	1.7e-134	452.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WXD1_k127_4510287_1	861299.J421_3234	9.778e-104	352.0	COG1625@1|root,COG1625@2|Bacteria,1ZSQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
WXD1_k127_4510287_4	309807.SRU_1715	6.385e-07	58.0	2DHC9@1|root,2ZZ7D@2|Bacteria,4PEUK@976|Bacteroidetes,1FJMV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
WXD1_k127_4510293_4	929562.Emtol_1136	4.739e-06	52.0	COG3250@1|root,COG4189@1|root,COG3250@2|Bacteria,COG4189@2|Bacteria,4NFPC@976|Bacteroidetes,47K4T@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	cbgA_1	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WXD1_k127_4510293_0	1340493.JNIF01000004_gene829	3.649e-266	831.0	COG0591@1|root,COG0591@2|Bacteria,3Y42K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WXD1_k127_4510293_3	861299.J421_6270	1.844e-18	88.0	2DJDE@1|root,305RC@2|Bacteria,1ZV7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4510293_1	861299.J421_4507	5.868e-95	325.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	galM	GO:0003674,GO:0003824,GO:0004034,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575	2.7.1.6,5.1.3.3	ko:K00849,ko:K01785	ko00010,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map00520,map01100,map01110,map01120,map01130	M00554,M00632	R01092,R01602,R10619	RC00002,RC00078,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iECH74115_1262.ECH74115_0859,iECSP_1301.ECSP_0809,iECs_1301.ECs0784,iZ_1308.Z0926	Aldose_epim
WXD1_k127_4510293_2	861299.J421_0357	1.557e-20	97.0	COG1629@1|root,COG1629@2|Bacteria,1ZU27@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
WXD1_k127_4513564_2	1121918.ARWE01000001_gene1528	1.175e-13	82.0	2AFPW@1|root,315RN@2|Bacteria,1N1K1@1224|Proteobacteria,42WWK@68525|delta/epsilon subdivisions,2WSXP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4513564_3	1379270.AUXF01000001_gene2769	3.514e-07	63.0	2A1DQ@1|root,30PKX@2|Bacteria,1ZUYB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4513564_1	316067.Geob_0291	7.853e-123	405.0	COG3266@1|root,COG3266@2|Bacteria,1RDC1@1224|Proteobacteria,42UDQ@68525|delta/epsilon subdivisions,2WTX3@28221|Deltaproteobacteria,43SY3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4513564_0	1047013.AQSP01000142_gene222	7.663e-189	615.0	COG1680@1|root,COG1680@2|Bacteria,2NNSA@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WXD1_k127_4536775_3	1122176.KB903569_gene3490	3.518e-33	130.0	2DEWU@1|root,2ZPJP@2|Bacteria,4NPJW@976|Bacteroidetes,1ITQ6@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4536775_4	582402.Hbal_0046	5.971e-10	63.0	COG5460@1|root,COG5460@2|Bacteria,1NQ45@1224|Proteobacteria,2UXM6@28211|Alphaproteobacteria,4403Z@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
WXD1_k127_4536775_1	861299.J421_2063	8.353e-113	378.0	COG0648@1|root,COG0648@2|Bacteria,1ZT71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
WXD1_k127_4536775_5	1379270.AUXF01000006_gene26	2.614e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WXD1_k127_4536775_2	1120954.ATXE01000001_gene1463	1.299e-42	168.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4DQM8@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
WXD1_k127_4536775_0	234267.Acid_4267	7.436e-137	456.0	COG0577@1|root,COG0577@2|Bacteria,3Y3U3@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_4568876_1	1123508.JH636446_gene6369	8.958e-90	313.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_4568876_2	100226.SCO2357	5.125e-08	57.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WXD1_k127_4568876_0	861299.J421_1999	9.823e-116	379.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Erythro_esteras,PCMT
WXD1_k127_4573597_1	358823.DF19_04355	4.935e-155	497.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WXD1_k127_4573597_6	713587.THITH_13560	1.742e-43	166.0	COG4290@1|root,COG4290@2|Bacteria	2|Bacteria	F	endoribonuclease activity	rnaSA	GO:0005575,GO:0005576	3.1.27.3	ko:K01167,ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
WXD1_k127_4573597_7	1123059.KB823012_gene2248	7.169e-43	162.0	COG5403@1|root,COG5403@2|Bacteria,1N0H4@1224|Proteobacteria,2UFMN@28211|Alphaproteobacteria,43XNE@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
WXD1_k127_4573597_0	861299.J421_6006	1.837e-206	676.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_4573597_5	861299.J421_2218	1.483e-55	196.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WXD1_k127_4573597_2	309807.SRU_0344	9.785e-102	344.0	COG0767@1|root,COG0767@2|Bacteria,4NEZ8@976|Bacteroidetes	976|Bacteroidetes	Q	ABC-type transport system involved in resistance to organic solvents permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WXD1_k127_4573597_3	309807.SRU_0343	1.926e-88	312.0	COG1127@1|root,COG1127@2|Bacteria,4NETG@976|Bacteroidetes,1FIW0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WXD1_k127_4573597_4	309807.SRU_0342	5.184e-73	257.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	pqiB	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WXD1_k127_4578273_1	1347368.HG964408_gene7112	7.459e-181	576.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli,1ZC7J@1386|Bacillus	91061|Bacilli	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WXD1_k127_4578273_2	861299.J421_3749	6.249e-88	301.0	COG1721@1|root,COG1721@2|Bacteria,1ZT0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WXD1_k127_4578273_3	379066.GAU_2149	1.841e-59	231.0	COG2304@1|root,COG2304@2|Bacteria,1ZT05@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
WXD1_k127_4578273_0	518766.Rmar_2754	1.258e-221	720.0	COG1197@1|root,COG1197@2|Bacteria,4NEPA@976|Bacteroidetes,1FIP1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WXD1_k127_4585033_1	452637.Oter_3065	2.425e-05	57.0	COG0823@1|root,COG3210@1|root,COG5276@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	domain, Protein	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3739,Germane,Gmad1,Haemagg_act,LVIVD
WXD1_k127_4585033_0	1379270.AUXF01000003_gene3398	4.567e-88	310.0	COG4796@1|root,COG4796@2|Bacteria,1ZSRT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	AMIN domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
WXD1_k127_4602792_0	221288.JH992901_gene3903	6.932e-193	614.0	COG2366@1|root,COG2366@2|Bacteria,1G0QT@1117|Cyanobacteria,1JK3D@1189|Stigonemataceae	1117|Cyanobacteria	S	Penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WXD1_k127_4603807_8	861299.J421_0936	2.568e-30	123.0	arCOG03092@1|root,32YMQ@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure	gvpA	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
WXD1_k127_4603807_9	861299.J421_0937	7.136e-30	123.0	2E5BC@1|root,3303G@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpJ	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
WXD1_k127_4603807_10	861299.J421_0938	1.111e-28	123.0	arCOG06390@1|root,330IR@2|Bacteria	2|Bacteria	S	Gas vesicle protein K	gvpK	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle,GvpK
WXD1_k127_4603807_15	58123.JOFJ01000007_gene758	3.421e-05	55.0	2DM5J@1|root,31T6B@2|Bacteria,2GMP8@201174|Actinobacteria,4ER57@85012|Streptosporangiales	201174|Actinobacteria	S	Gas vesicle synthesis protein GvpL/GvpF	gvpL2	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
WXD1_k127_4603807_14	319225.Plut_0704	2.714e-09	66.0	2DRDP@1|root,33BB6@2|Bacteria	2|Bacteria	S	Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth	gvpS1	-	-	-	-	-	-	-	-	-	-	-	Gas_vesicle
WXD1_k127_4603807_11	861299.J421_0941	1.337e-26	122.0	2C8AD@1|root,32RKP@2|Bacteria	2|Bacteria	S	Gas vesicle	-	-	-	-	-	-	-	-	-	-	-	-	GvpL_GvpF
WXD1_k127_4603807_3	861299.J421_0942	1.618e-73	273.0	COG0003@1|root,COG0003@2|Bacteria,1ZVAB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
WXD1_k127_4603807_0	861299.J421_0944	1.79e-108	374.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
WXD1_k127_4603807_6	861299.J421_3088	3.476e-67	252.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
WXD1_k127_4603807_7	501479.ACNW01000062_gene2730	4.64e-48	196.0	COG0492@1|root,COG0492@2|Bacteria,1MVWS@1224|Proteobacteria,2TU6F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WXD1_k127_4603807_13	861299.J421_1004	5.751e-15	85.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WXD1_k127_4603807_4	1134413.ANNK01000094_gene900	1.312e-72	266.0	COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli,1ZCXK@1386|Bacillus	91061|Bacilli	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
WXD1_k127_4603807_2	316274.Haur_0795	2.551e-88	313.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,LuxE
WXD1_k127_4603807_1	1051632.TPY_0663	4.184e-92	325.0	COG1331@1|root,COG1331@2|Bacteria,1TPRD@1239|Firmicutes,248PD@186801|Clostridia	186801|Clostridia	O	Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
WXD1_k127_4603807_5	1173029.JH980292_gene4049	7.214e-68	254.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,1G0GI@1117|Cyanobacteria,1H9N1@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
WXD1_k127_4603807_16	1349767.GJA_4123	0.0003634	47.0	COG3237@1|root,COG3237@2|Bacteria	2|Bacteria	K	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
WXD1_k127_4621902_7	159087.Daro_3292	1.741e-19	104.0	2CDCV@1|root,308Y1@2|Bacteria,1N74F@1224|Proteobacteria,2VSMP@28216|Betaproteobacteria,2KWQ8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4621902_5	404589.Anae109_4499	2.727e-24	110.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WXD1_k127_4621902_0	861299.J421_3508	1.278e-175	575.0	COG2256@1|root,COG2256@2|Bacteria,1ZTCA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
WXD1_k127_4621902_4	240015.ACP_2776	4.167e-48	183.0	COG0428@1|root,COG0428@2|Bacteria,3Y4A7@57723|Acidobacteria,2JJ1K@204432|Acidobacteriia	204432|Acidobacteriia	P	ZIP Zinc transporter	-	-	-	ko:K07238,ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11,2.A.5.5	-	-	Zip
WXD1_k127_4621902_2	861299.J421_3513	4.427e-86	301.0	COG0617@1|root,COG0617@2|Bacteria,1ZSKW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WXD1_k127_4621902_1	1379270.AUXF01000006_gene48	2.349e-90	304.0	COG1028@1|root,COG1028@2|Bacteria,1ZTJK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WXD1_k127_4621902_3	861299.J421_3519	2.561e-58	214.0	COG0279@1|root,COG0279@2|Bacteria,1ZTY5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WXD1_k127_4621902_6	861299.J421_3522	5.478e-23	103.0	COG0013@1|root,COG0013@2|Bacteria,1ZT18@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WXD1_k127_4626280_2	379066.GAU_0788	1.15e-37	151.0	COG2236@1|root,COG2236@2|Bacteria,1ZTQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
WXD1_k127_4626280_0	1379698.RBG1_1C00001G0312	5.3e-191	604.0	COG1158@1|root,COG1158@2|Bacteria,2NNXC@2323|unclassified Bacteria	2|Bacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K02887,ko:K03628	ko03010,ko03018,map03010,map03018	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WXD1_k127_4626280_3	861299.J421_3475	3.442e-10	72.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	ttg2C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WXD1_k127_4626280_1	243231.GSU2017	1.208e-40	162.0	COG1427@1|root,COG1427@2|Bacteria,1RCS0@1224|Proteobacteria,42SPW@68525|delta/epsilon subdivisions,2WP7F@28221|Deltaproteobacteria,43U6I@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
WXD1_k127_4678724_0	1232437.KL662020_gene770	8.762e-90	311.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,2MJ25@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
WXD1_k127_4678724_1	1125863.JAFN01000001_gene2836	5.359e-57	203.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,42NN1@68525|delta/epsilon subdivisions,2WNNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WXD1_k127_4691655_1	661478.OP10G_0109	6.32e-92	318.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6,2.7.11.1,3.1.4.53	ko:K03651,ko:K05889,ko:K12132	ko00230,ko02025,map00230,map02025	-	R00191,R03136	RC00296	ko00000,ko00001,ko01000,ko01001	-	-	-	Cytochrome_CBB3,DUF1863,Metallophos,MetallophosN,PQQ,PQQ_2,PQQ_3
WXD1_k127_4691655_0	1313172.YM304_27660	1.227e-228	735.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
WXD1_k127_4700268_1	246197.MXAN_2783	1.708e-155	521.0	COG0577@1|root,COG0577@2|Bacteria,1PIKV@1224|Proteobacteria	1224|Proteobacteria	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_4700268_6	574375.BAGA_29135	1.78e-06	62.0	COG3391@1|root,COG3391@2|Bacteria,1VCN6@1239|Firmicutes,4IQ7U@91061|Bacilli,1ZRHV@1386|Bacillus	91061|Bacilli	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
WXD1_k127_4700268_3	1047013.AQSP01000079_gene2044	9.364e-49	200.0	COG0845@1|root,COG0845@2|Bacteria,2NR3D@2323|unclassified Bacteria	2|Bacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WXD1_k127_4700268_5	411477.PARMER_01363	1.433e-06	61.0	COG1538@1|root,COG1538@2|Bacteria,4NEEN@976|Bacteroidetes,2FM98@200643|Bacteroidia,22WWD@171551|Porphyromonadaceae	976|Bacteroidetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WXD1_k127_4700268_0	945713.IALB_0693	1.224e-210	693.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	mdtC	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WXD1_k127_4700268_2	1379270.AUXF01000004_gene3210	2.158e-154	526.0	COG0841@1|root,COG0841@2|Bacteria,1ZUFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WXD1_k127_4700268_4	869210.Marky_0007	2.46e-39	164.0	COG0477@1|root,COG2814@2|Bacteria,1WJAR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1,Sugar_tr
WXD1_k127_4705898_4	861299.J421_2545	5.183e-45	188.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
WXD1_k127_4705898_3	861299.J421_2338	3.031e-88	321.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	2|Bacteria	M	Surface antigen	-	-	-	ko:K07277,ko:K07278	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
WXD1_k127_4705898_1	243090.RB11266	4.272e-102	354.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	cpdA	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
WXD1_k127_4705898_0	379066.GAU_0619	1.614e-107	366.0	COG0533@1|root,COG0533@2|Bacteria,1ZT0P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WXD1_k127_4705898_7	1121413.JMKT01000012_gene686	0.000184	51.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,2MC38@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
WXD1_k127_4705898_5	768671.ThimaDRAFT_1213	3.506e-33	136.0	COG0526@1|root,COG0526@2|Bacteria,1RJUZ@1224|Proteobacteria,1S6Y0@1236|Gammaproteobacteria,1WYNQ@135613|Chromatiales	135613|Chromatiales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WXD1_k127_4705898_6	1172180.KB911776_gene745	2.927e-08	64.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WXD1_k127_4705898_2	861299.J421_2565	1.131e-97	332.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1ZTGM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
WXD1_k127_471221_5	1124780.ANNU01000005_gene2549	8.044e-63	248.0	COG2234@1|root,COG2234@2|Bacteria,4NG2A@976|Bacteroidetes,47KMC@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M28	ywaD	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WXD1_k127_471221_2	379066.GAU_2571	5.855e-161	570.0	COG1747@1|root,COG1747@2|Bacteria,1ZT0K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	RNA polymerase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_471221_3	379066.GAU_2572	4.713e-81	310.0	COG0795@1|root,COG0795@2|Bacteria,1ZTJR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WXD1_k127_471221_4	1379270.AUXF01000001_gene2819	1.11e-63	239.0	COG0795@1|root,COG0795@2|Bacteria,1ZSNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
WXD1_k127_471221_6	515635.Dtur_0778	2.565e-56	214.0	COG0253@1|root,COG0253@2|Bacteria	2|Bacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
WXD1_k127_471221_0	880073.Calab_1134	1.726e-234	755.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WXD1_k127_471221_7	398767.Glov_3037	1.177e-12	81.0	COG0593@1|root,COG1943@1|root,COG0593@2|Bacteria,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	SMART Chromosomal replication initiator DnaA domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
WXD1_k127_471221_1	1379270.AUXF01000004_gene3330	8.722e-196	621.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
WXD1_k127_4722489_5	379066.GAU_1206	5.509e-06	50.0	COG0360@1|root,COG0360@2|Bacteria,1ZTYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WXD1_k127_4722489_3	379066.GAU_1205	2.831e-23	101.0	COG0238@1|root,COG0238@2|Bacteria,1ZU47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WXD1_k127_4722489_4	1379270.AUXF01000005_gene511	3.04e-12	77.0	2F1RZ@1|root,33US3@2|Bacteria,1ZUSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
WXD1_k127_4722489_1	861299.J421_2950	2.036e-38	160.0	COG0359@1|root,COG0359@2|Bacteria,1ZTNG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WXD1_k127_4722489_2	1379270.AUXF01000005_gene509	2.139e-34	136.0	COG0799@1|root,COG0799@2|Bacteria,1ZU0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WXD1_k127_4722489_0	861299.J421_2948	1.365e-185	614.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
WXD1_k127_4730229_7	1385513.N780_13515	3.1e-05	56.0	COG3153@1|root,COG3153@2|Bacteria,1V0I4@1239|Firmicutes,4HCMH@91061|Bacilli,2YB6D@289201|Pontibacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WXD1_k127_4730229_4	861299.J421_0966	2.818e-20	100.0	2E40T@1|root,32YXK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4730229_5	483219.LILAB_05190	2.916e-16	85.0	2C12A@1|root,33B7C@2|Bacteria,1NMUW@1224|Proteobacteria,434ZQ@68525|delta/epsilon subdivisions,2X93I@28221|Deltaproteobacteria,2Z1Q3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4730229_3	1379270.AUXF01000003_gene3745	1.996e-35	151.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WXD1_k127_4730229_2	861299.J421_5817	2.265e-71	259.0	COG2819@1|root,COG2819@2|Bacteria,1ZV8W@142182|Gemmatimonadetes	2|Bacteria	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
WXD1_k127_4730229_0	1284352.AOIG01000032_gene330	2.691e-261	821.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli,26R74@186822|Paenibacillaceae	91061|Bacilli	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WXD1_k127_4730229_6	861299.J421_2729	1.1e-15	83.0	COG5512@1|root,COG5512@2|Bacteria,1ZTYN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
WXD1_k127_4730229_1	861299.J421_2731	2.471e-78	275.0	COG1195@1|root,COG1195@2|Bacteria,1ZSRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WXD1_k127_474817_1	861299.J421_0996	1.181e-95	329.0	COG0557@1|root,COG0557@2|Bacteria	2|Bacteria	K	exoribonuclease II activity	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WXD1_k127_474817_2	330214.NIDE3508	1.236e-51	197.0	28N6F@1|root,2ZBBB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_474817_3	663610.JQKO01000015_gene1906	7.84e-41	172.0	COG0642@1|root,COG2972@1|root,COG2205@2|Bacteria,COG2972@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria,3N9SQ@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
WXD1_k127_474817_4	378806.STAUR_4294	6.527e-19	101.0	COG0467@1|root,COG0467@2|Bacteria	2|Bacteria	T	regulation of circadian rhythm	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
WXD1_k127_474817_0	378806.STAUR_4295	3.494e-106	363.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42YYA@68525|delta/epsilon subdivisions,2WTU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
WXD1_k127_4799765_3	936572.HMPREF1148_0722	1.529e-71	247.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H408@909932|Negativicutes	909932|Negativicutes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	-	-	-	-	-	-	-	-	-	-	Pro_isomerase
WXD1_k127_4799765_2	13035.Dacsa_3298	4.32e-82	287.0	COG4221@1|root,COG4221@2|Bacteria,1G182@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
WXD1_k127_4799765_1	861299.J421_2200	2.006e-84	290.0	COG0673@1|root,COG0673@2|Bacteria,1ZSRB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WXD1_k127_4799765_4	861299.J421_2200	1.052e-64	227.0	COG0673@1|root,COG0673@2|Bacteria,1ZSRB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WXD1_k127_4799765_5	861299.J421_2204	7.625e-60	217.0	COG1209@1|root,COG1209@2|Bacteria	2|Bacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	GalU	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WXD1_k127_4799765_0	1122179.KB890441_gene1057	1.462e-217	690.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1IW3G@117747|Sphingobacteriia	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WXD1_k127_4841475_14	1278073.MYSTI_04415	5.932e-18	89.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2YVGD@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WXD1_k127_4841475_9	861299.J421_3229	4.839e-61	231.0	COG4365@1|root,COG4365@2|Bacteria,1ZTG0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacillithiol biosynthesis BshC	-	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
WXD1_k127_4841475_12	861299.J421_3228	1.638e-35	142.0	COG1576@1|root,COG1576@2|Bacteria,1ZTQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WXD1_k127_4841475_1	861299.J421_3227	1.467e-202	637.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WXD1_k127_4841475_3	243231.GSU1827	2.75e-153	515.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,43TWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WXD1_k127_4841475_10	861299.J421_3226	2.677e-50	192.0	COG1663@1|root,COG1663@2|Bacteria,1ZTIE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
WXD1_k127_4841475_11	1316936.K678_02208	1.959e-42	166.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,2JS37@204441|Rhodospirillales	204441|Rhodospirillales	S	protein conserved in bacteria	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
WXD1_k127_4841475_6	861299.J421_3224	7.522e-89	306.0	COG0763@1|root,COG0763@2|Bacteria,1ZTAD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
WXD1_k127_4841475_7	861299.J421_3223	3.169e-88	312.0	COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WXD1_k127_4841475_8	1379270.AUXF01000006_gene299	7.531e-79	271.0	COG1043@1|root,COG1043@2|Bacteria,1ZT7T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
WXD1_k127_4841475_4	1379270.AUXF01000006_gene300	8.998e-141	462.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
WXD1_k127_4841475_5	861299.J421_3220	7.846e-97	327.0	COG1044@1|root,COG1044@2|Bacteria,1ZSRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
WXD1_k127_4841475_13	1379270.AUXF01000006_gene302	3.199e-24	109.0	COG2825@1|root,COG2825@2|Bacteria,1ZU5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
WXD1_k127_4841475_2	861299.J421_3218	1.248e-178	594.0	COG4775@1|root,COG4775@2|Bacteria,1ZT6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WXD1_k127_4841475_0	555079.Toce_2123	1.69e-311	974.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,42FKB@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WXD1_k127_4841475_15	379066.GAU_1583	6.373e-06	49.0	COG3869@1|root,COG3869@2|Bacteria,1ZT9I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP:guanido phosphotransferase, C-terminal catalytic domain	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
WXD1_k127_4844791_3	1173023.KE650771_gene2605	1.867e-35	151.0	COG3386@1|root,COG3386@2|Bacteria,1G05C@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
WXD1_k127_4844791_0	251221.35214024	5.842e-183	589.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
WXD1_k127_4844791_1	234267.Acid_2673	9.814e-62	226.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
WXD1_k127_4844791_2	1499967.BAYZ01000027_gene1815	6.989e-59	211.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WXD1_k127_4861117_1	1234664.AMRO01000077_gene3432	3.724e-104	350.0	COG3876@1|root,COG3876@2|Bacteria,1VRMG@1239|Firmicutes,4HA8F@91061|Bacilli,1WFX8@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF1343)	ybbC	-	-	-	-	-	-	-	-	-	-	-	DUF1343
WXD1_k127_4861117_0	1318628.MARLIPOL_05115	1.673e-128	440.0	COG3525@1|root,COG3525@2|Bacteria,1QR2G@1224|Proteobacteria,1RZNM@1236|Gammaproteobacteria,466IG@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	beta-N-acetylglucosaminidase	-	-	3.2.1.35	ko:K01197	ko00531,ko01100,map00531,map01100	M00076,M00077	R07824,R07825,R10905	-	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	-	-	Glyco_hydro_20b,NAGidase
WXD1_k127_4861117_2	395961.Cyan7425_2694	0.0001499	45.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,3KG3G@43988|Cyanothece	1117|Cyanobacteria	S	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WXD1_k127_4863960_4	269799.Gmet_2147	2.955e-63	226.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,42PAQ@68525|delta/epsilon subdivisions,2WMYT@28221|Deltaproteobacteria,43UHE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
WXD1_k127_4863960_0	935948.KE386494_gene365	4.363e-158	527.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,42FKN@68295|Thermoanaerobacterales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WXD1_k127_4863960_12	1382315.JPOI01000001_gene368	1.796e-16	93.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,4HA30@91061|Bacilli,1WEDY@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF445)	yheB	-	-	-	-	-	-	-	-	-	-	-	DUF445
WXD1_k127_4863960_9	1521187.JPIM01000131_gene1453	4.835e-23	104.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi,377ME@32061|Chloroflexia	32061|Chloroflexia	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
WXD1_k127_4863960_6	1048834.TC41_2569	1.034e-47	192.0	COG0483@1|root,COG0483@2|Bacteria,1UKWB@1239|Firmicutes,4ITKN@91061|Bacilli	91061|Bacilli	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WXD1_k127_4863960_2	379066.GAU_0825	1.372e-143	481.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
WXD1_k127_4863960_3	379066.GAU_0826	2.729e-92	311.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_4863960_5	177437.HRM2_33700	3.927e-59	224.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WXD1_k127_4863960_11	670487.Ocepr_1964	3.405e-18	95.0	COG2110@1|root,COG2110@2|Bacteria,1WJ1P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
WXD1_k127_4863960_14	1173264.KI913949_gene1836	2.932e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria,1HE7X@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
WXD1_k127_4863960_7	290397.Adeh_1133	2.788e-31	126.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
WXD1_k127_4863960_1	240015.ACP_0820	8.715e-153	503.0	COG1022@1|root,COG1022@2|Bacteria,3Y2KU@57723|Acidobacteria,2JHTA@204432|Acidobacteriia	204432|Acidobacteriia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
WXD1_k127_4863960_10	526227.Mesil_1405	1.755e-19	93.0	COG1765@1|root,COG1765@2|Bacteria,1WJW4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	redox protein regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WXD1_k127_4863960_8	861299.J421_2711	5.892e-31	128.0	COG0457@1|root,COG0457@2|Bacteria,1ZTX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
WXD1_k127_4863960_15	335543.Sfum_1245	0.0001326	51.0	COG0500@1|root,COG2835@1|root,COG2226@2|Bacteria,COG2835@2|Bacteria,1R5RG@1224|Proteobacteria,42NHW@68525|delta/epsilon subdivisions,2WKI8@28221|Deltaproteobacteria,2MR8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	Trm112p-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Trm112p
WXD1_k127_4863960_13	579405.Dd703_2141	7.839e-16	87.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,2JD3P@204037|Dickeya	1236|Gammaproteobacteria	M	Opacity-associated protein A domain protein	yebA	GO:0000270,GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008237,GO:0009987,GO:0012501,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564	-	ko:K19304	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	OapA,OapA_N,Peptidase_M23
WXD1_k127_4891880_1	251221.35211248	4.677e-21	99.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WXD1_k127_4891880_0	234267.Acid_0751	4.379e-159	539.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_4904542_12	1687.BCOR_1243	3.102e-22	96.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4D19N@85004|Bifidobacteriales	201174|Actinobacteria	J	Ribosomal L27 protein	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WXD1_k127_4904542_11	861299.J421_3337	2.153e-30	123.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WXD1_k127_4904542_3	1499967.BAYZ01000029_gene1223	2.798e-128	426.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
WXD1_k127_4904542_2	861299.J421_3340	9.806e-159	509.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WXD1_k127_4904542_4	861299.J421_3341	1.086e-125	424.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
WXD1_k127_4904542_7	1313301.AUGC01000015_gene1856	5.609e-51	195.0	COG1024@1|root,COG1024@2|Bacteria,4NI32@976|Bacteroidetes	976|Bacteroidetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WXD1_k127_4904542_9	861299.J421_3344	1.556e-31	141.0	2CIU6@1|root,32S8H@2|Bacteria,1ZTUM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4904542_1	1379270.AUXF01000006_gene185	2.456e-198	629.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
WXD1_k127_4904542_0	379066.GAU_1707	6.409e-236	743.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
WXD1_k127_4904542_6	861299.J421_3347	1.825e-58	206.0	COG2185@1|root,COG2185@2|Bacteria,1ZTNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WXD1_k127_4904542_8	861299.J421_3348	1.719e-49	188.0	COG0500@1|root,COG2226@2|Bacteria,1ZTCQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WXD1_k127_4904542_5	1379270.AUXF01000003_gene3384	1.267e-105	365.0	COG1253@1|root,COG1253@2|Bacteria,1ZT0D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WXD1_k127_4904542_10	671143.DAMO_0482	3.612e-31	127.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
WXD1_k127_4921408_3	1269813.ATUL01000024_gene698	2.878e-41	157.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
WXD1_k127_4921408_7	314278.NB231_03135	0.0009685	48.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,DDE_Tnp_IS66,PRiA4_ORF3,Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase
WXD1_k127_4921408_5	379066.GAU_3293	1.253e-29	123.0	294EW@1|root,2ZRUR@2|Bacteria,1ZV2S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
WXD1_k127_4921408_0	1382356.JQMP01000003_gene1430	2.822e-69	243.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,27YVM@189775|Thermomicrobia	189775|Thermomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WXD1_k127_4921408_1	309801.trd_1817	3.328e-58	217.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
WXD1_k127_4921408_4	518766.Rmar_1382	7.696e-39	159.0	COG3439@1|root,COG3439@2|Bacteria,4NQRI@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WXD1_k127_4921408_2	379066.GAU_1739	4.167e-49	201.0	2DEWU@1|root,2ZPJP@2|Bacteria,1ZUFA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_4921408_6	861299.J421_2063	5.891e-11	63.0	COG0648@1|root,COG0648@2|Bacteria,1ZT71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Xylose isomerase-like TIM barrel	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
WXD1_k127_4943068_1	234267.Acid_0605	4.011e-55	219.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria	57723|Acidobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WXD1_k127_4943068_4	1403819.BATR01000016_gene491	1.344e-20	94.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	MA20_40075	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WXD1_k127_4943068_5	1278073.MYSTI_03840	3.019e-20	98.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WXD1_k127_4943068_0	518766.Rmar_2509	2.105e-113	374.0	COG0812@1|root,COG0812@2|Bacteria,4PEBS@976|Bacteroidetes,1FISG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WXD1_k127_4943068_2	1379270.AUXF01000001_gene2333	3.131e-41	158.0	COG5531@1|root,COG5531@2|Bacteria,1ZTZP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
WXD1_k127_4943068_3	1174684.EBMC1_05969	5.2e-36	150.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,2UC22@28211|Alphaproteobacteria,2K541@204457|Sphingomonadales	204457|Sphingomonadales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
WXD1_k127_494391_0	1189612.A33Q_0192	4.485e-155	518.0	COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,47K5T@768503|Cytophagia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_494391_4	886293.Sinac_6448	3.759e-61	216.0	COG0503@1|root,COG0503@2|Bacteria,2IZ9H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WXD1_k127_494391_2	1166130.H650_07485	6.109e-82	277.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,1RPB1@1236|Gammaproteobacteria,3X18B@547|Enterobacter	1236|Gammaproteobacteria	S	SNARE associated Golgi protein	dedA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
WXD1_k127_494391_3	861299.J421_3240	1.11e-65	235.0	COG2518@1|root,COG2518@2|Bacteria,1ZTED@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WXD1_k127_494391_1	379066.GAU_1605	3.073e-82	286.0	COG0496@1|root,COG0496@2|Bacteria,1ZT6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WXD1_k127_494391_5	379066.GAU_1604	9.795e-32	132.0	COG0789@1|root,COG0789@2|Bacteria,1ZTSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
WXD1_k127_494391_7	592015.HMPREF1705_01796	1.661e-05	47.0	COG0240@1|root,COG0240@2|Bacteria,3TA1T@508458|Synergistetes	508458|Synergistetes	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WXD1_k127_4944744_3	861299.J421_1297	4.791e-50	181.0	COG0821@1|root,COG0821@2|Bacteria,1ZST3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
WXD1_k127_4944744_4	379066.GAU_1401	1.343e-31	136.0	COG0597@1|root,COG0597@2|Bacteria,1ZTWA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WXD1_k127_4944744_1	525904.Tter_1676	4.876e-54	197.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WXD1_k127_4944744_2	861299.J421_1590	1.79e-53	205.0	COG0083@1|root,COG0083@2|Bacteria	2|Bacteria	E	homoserine kinase activity	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620	GHMP_kinases_C,GHMP_kinases_N
WXD1_k127_4944744_0	1540221.JQNI01000002_gene2346	1.965e-60	217.0	COG0498@1|root,COG0498@2|Bacteria,1WIAX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WXD1_k127_4951885_3	382464.ABSI01000013_gene1702	6.351e-36	139.0	COG1352@1|root,COG1352@2|Bacteria,46VVK@74201|Verrucomicrobia,2IUTZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NT	Methyltransferase, chemotaxis proteins	-	-	-	-	-	-	-	-	-	-	-	-	CheR
WXD1_k127_4951885_2	861299.J421_0157	8.459e-52	191.0	COG1871@1|root,COG1871@2|Bacteria,1ZTR7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	-	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
WXD1_k127_4951885_4	379066.GAU_0364	6.791e-30	132.0	COG0745@1|root,COG0745@2|Bacteria,1ZTZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WXD1_k127_4951885_7	861299.J421_0155	5.472e-17	87.0	COG1406@1|root,COG1406@2|Bacteria,1ZU7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
WXD1_k127_4951885_1	1379270.AUXF01000002_gene1698	3.177e-131	427.0	COG2201@1|root,COG2201@2|Bacteria,1ZTC0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WXD1_k127_4951885_6	861299.J421_0173	7.499e-22	103.0	COG1699@1|root,COG1699@2|Bacteria,1ZU5X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
WXD1_k127_4951885_5	586416.GZ22_16375	1.418e-23	117.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,4HCCZ@91061|Bacilli	91061|Bacilli	N	Belongs to the bacterial flagellin family	flgL	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WXD1_k127_4951885_0	1379270.AUXF01000002_gene1669	3.108e-149	482.0	COG2204@1|root,COG2204@2|Bacteria,1ZTDN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_4959766_2	1219049.SP5_097_00610	1.747e-16	92.0	COG1680@1|root,COG1680@2|Bacteria,1NHIY@1224|Proteobacteria,2U0A3@28211|Alphaproteobacteria,2K5YI@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_4959766_0	861299.J421_2513	3.58e-187	608.0	COG4867@1|root,COG4867@2|Bacteria,1ZT0B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
WXD1_k127_4959766_1	1157490.EL26_03175	8.178e-76	284.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,277VD@186823|Alicyclobacillaceae	91061|Bacilli	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
WXD1_k127_4969313_1	861299.J421_6349	1.953e-25	112.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WXD1_k127_4969313_0	861299.J421_2688	5.442e-76	262.0	COG1435@1|root,COG1435@2|Bacteria,1ZTB2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WXD1_k127_4995610_1	880074.BARVI_06100	3.362e-110	374.0	COG2385@1|root,COG2385@2|Bacteria,4NG21@976|Bacteroidetes,2FP4W@200643|Bacteroidia,22X5F@171551|Porphyromonadaceae	976|Bacteroidetes	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	DUF4922,Glycos_transf_2,SpoIID
WXD1_k127_4995610_2	886379.AEWI01000007_gene755	1.964e-39	169.0	COG4360@1|root,COG4360@2|Bacteria,4NHAH@976|Bacteroidetes,2FMAC@200643|Bacteroidia,3XJT1@558415|Marinilabiliaceae	976|Bacteroidetes	F	Domain of unknown function (DUF4922)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4922
WXD1_k127_4995610_0	1122981.AUME01000036_gene1559	2.071e-134	443.0	COG0463@1|root,COG4468@1|root,COG0463@2|Bacteria,COG4468@2|Bacteria,4PN1V@976|Bacteroidetes,2G0PG@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4922,Glycos_transf_2
WXD1_k127_5012639_6	485917.Phep_1294	4.218e-84	291.0	COG3250@1|root,COG3250@2|Bacteria,4NGNR@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
WXD1_k127_5012639_3	1033732.CAHI01000022_gene1524	1.008e-143	478.0	COG2931@1|root,COG3525@1|root,COG2931@2|Bacteria,COG3525@2|Bacteria,4P00M@976|Bacteroidetes,2FZPM@200643|Bacteroidia	976|Bacteroidetes	Q	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
WXD1_k127_5012639_0	485917.Phep_1292	4.915e-267	848.0	COG3250@1|root,COG3250@2|Bacteria,4NEDF@976|Bacteroidetes,1IR7F@117747|Sphingobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Malectin
WXD1_k127_5012639_1	762984.HMPREF9445_01895	1.226e-212	701.0	COG3250@1|root,COG3250@2|Bacteria,4NGNR@976|Bacteroidetes,2FQ2C@200643|Bacteroidia,4ANIJ@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
WXD1_k127_5012639_5	266117.Rxyl_0080	2.426e-85	291.0	COG1028@1|root,COG1028@2|Bacteria	266117.Rxyl_0080|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5012639_4	452637.Oter_4342	7.523e-141	456.0	COG1312@1|root,COG1312@2|Bacteria,46UDP@74201|Verrucomicrobia,3K8B6@414999|Opitutae	414999|Opitutae	G	Catalyzes the dehydration of D-mannonate	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
WXD1_k127_5012639_2	861299.J421_0375	1.561e-174	559.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
WXD1_k127_5012639_7	861299.J421_0377	8.285e-67	235.0	COG0800@1|root,COG0800@2|Bacteria	2|Bacteria	G	2-dehydro-3-deoxy-phosphogluconate aldolase activity	eda	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.1.45,4.1.2.14,4.1.3.42	ko:K00874,ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R01541,R05605	RC00002,RC00017,RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
WXD1_k127_5015531_2	861299.J421_6370	9.999e-82	275.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1ZTGF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CH	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
WXD1_k127_5015531_3	861299.J421_6372	1.178e-80	286.0	COG1028@1|root,COG1028@2|Bacteria,1ZTPZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WXD1_k127_5015531_1	1380394.JADL01000017_gene523	1.604e-128	415.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria,2JQRS@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WXD1_k127_5015531_0	1380394.JADL01000017_gene522	2.089e-130	442.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,2JPUP@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WXD1_k127_5015531_4	504728.K649_11955	5.123e-13	81.0	COG0365@1|root,COG0365@2|Bacteria,1WNGH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
WXD1_k127_5026587_0	234267.Acid_3077	5.846e-260	835.0	COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria	57723|Acidobacteria	Q	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
WXD1_k127_5026587_1	234267.Acid_3076	5.735e-16	87.0	COG2091@1|root,COG2091@2|Bacteria,3Y8HB@57723|Acidobacteria	57723|Acidobacteria	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WXD1_k127_5035905_0	945713.IALB_1169	4.759e-55	222.0	COG1629@1|root,COG4772@1|root,COG4771@2|Bacteria,COG4772@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_5035905_1	518766.Rmar_2301	2.123e-13	84.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_2301|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5066901_7	1379270.AUXF01000001_gene2737	3.66e-52	191.0	COG1506@1|root,COG1506@2|Bacteria,1ZSYK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WXD1_k127_5066901_1	926560.KE387023_gene1159	3.498e-149	484.0	COG0513@1|root,COG0513@2|Bacteria,1WKZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WXD1_k127_5066901_0	518766.Rmar_0629	0.0	1049.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,4NERT@976|Bacteroidetes,1FJ3R@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	BSP,Bac_surface_Ag,PD40
WXD1_k127_5066901_4	290397.Adeh_0291	6.157e-112	391.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
WXD1_k127_5066901_5	1071679.BG57_12690	2.881e-83	288.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,2VKI0@28216|Betaproteobacteria,1K199@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WXD1_k127_5066901_8	1279019.ARQK01000034_gene1115	3.134e-23	113.0	COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,1T4M3@1236|Gammaproteobacteria,1WY59@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,PAS_9
WXD1_k127_5066901_3	861299.J421_4432	8.685e-113	378.0	COG1502@1|root,COG1502@2|Bacteria,1ZTU6@142182|Gemmatimonadetes	2|Bacteria	I	Phospholipase D. Active site motifs.	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
WXD1_k127_5066901_9	861299.J421_1913	9.988e-09	59.0	COG0828@1|root,COG0828@2|Bacteria,1ZU81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S21	-	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WXD1_k127_5066901_2	240015.ACP_3363	5.317e-142	465.0	COG0773@1|root,COG0773@2|Bacteria,3Y2M2@57723|Acidobacteria,2JIE2@204432|Acidobacteriia	204432|Acidobacteriia	M	Mur ligase middle domain	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WXD1_k127_5066901_6	1112214.AHIS01000047_gene2118	1.463e-58	224.0	COG2234@1|root,COG2234@2|Bacteria,1MVYE@1224|Proteobacteria,2VF5N@28211|Alphaproteobacteria,2KDVY@204457|Sphingomonadales	204457|Sphingomonadales	V	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WXD1_k127_5079831_0	525903.Taci_0981	1.168e-172	571.0	COG1067@1|root,COG1067@2|Bacteria,3T9SS@508458|Synergistetes	508458|Synergistetes	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
WXD1_k127_5079831_3	861299.J421_0116	7.52e-41	155.0	COG1846@1|root,COG1846@2|Bacteria,1ZTUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR_2
WXD1_k127_5079831_2	292459.STH1902	5.746e-57	212.0	COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,24N6D@186801|Clostridia	186801|Clostridia	S	Dienelactone hydrolase family	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,DLH
WXD1_k127_5079831_1	1379270.AUXF01000007_gene875	7.067e-83	296.0	COG0656@1|root,COG0656@2|Bacteria,1ZURF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WXD1_k127_5084441_1	289376.THEYE_A0992	2.44e-103	365.0	COG1009@1|root,COG1009@2|Bacteria,3J1FJ@40117|Nitrospirae	40117|Nitrospirae	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WXD1_k127_5084441_0	269796.Rru_A0314	8.642e-118	402.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TRIR@28211|Alphaproteobacteria,2JV8J@204441|Rhodospirillales	204441|Rhodospirillales	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	-	ko:K12139	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WXD1_k127_5084441_5	269796.Rru_A0322	2.609e-18	93.0	COG0680@1|root,COG0680@2|Bacteria,1R3V7@1224|Proteobacteria,2UMM4@28211|Alphaproteobacteria,2JY79@204441|Rhodospirillales	204441|Rhodospirillales	C	Hydrogenase maturation protease	-	-	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
WXD1_k127_5084441_2	635013.TherJR_0672	1.743e-92	315.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,2676A@186807|Peptococcaceae	186801|Clostridia	C	Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
WXD1_k127_5084441_4	338966.Ppro_2789	2.241e-46	189.0	COG1150@1|root,COG1150@2|Bacteria,1QWNB@1224|Proteobacteria,43BTA@68525|delta/epsilon subdivisions,2X741@28221|Deltaproteobacteria,43VYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
WXD1_k127_5084441_3	1452718.JBOY01000190_gene851	5.716e-59	227.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WXD1_k127_5088382_0	373994.Riv7116_4837	6.351e-153	499.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1HQTX@1161|Nostocales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
WXD1_k127_5088382_1	861299.J421_2044	2.026e-34	149.0	2EXVN@1|root,33R4S@2|Bacteria,1ZTD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5092234_0	1210884.HG799464_gene10774	3.931e-184	606.0	COG1228@1|root,COG1228@2|Bacteria,2IYFS@203682|Planctomycetes	203682|Planctomycetes	Q	COG1228 Imidazolonepropionase and related	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WXD1_k127_5092234_4	861299.J421_0415	1.503e-100	356.0	COG0840@1|root,COG0840@2|Bacteria,1ZUEF@142182|Gemmatimonadetes	2|Bacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,DUF3365,HAMP,MCPsignal,dCache_1
WXD1_k127_5092234_2	935863.AWZR01000014_gene2956	3.726e-113	377.0	COG0451@1|root,COG0451@2|Bacteria,1NQXJ@1224|Proteobacteria,1T0SB@1236|Gammaproteobacteria,1XD1F@135614|Xanthomonadales	135614|Xanthomonadales	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
WXD1_k127_5092234_1	1096546.WYO_3299	4.32e-124	415.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria,1JRBF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	ATP ADP translocase	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	MFS_1,TLC
WXD1_k127_5092234_5	266117.Rxyl_0307	1.689e-96	325.0	COG0584@1|root,COG0584@2|Bacteria,2GM8K@201174|Actinobacteria,4CRQK@84995|Rubrobacteria	84995|Rubrobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WXD1_k127_5092234_6	525904.Tter_2416	4.079e-94	318.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	alx	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
WXD1_k127_5092234_8	1519464.HY22_08895	1.506e-21	107.0	COG1277@1|root,COG1277@2|Bacteria,1FFEA@1090|Chlorobi	1090|Chlorobi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
WXD1_k127_5092234_3	1519464.HY22_05180	6.06e-102	341.0	COG1131@1|root,COG1131@2|Bacteria,1FF0I@1090|Chlorobi	1090|Chlorobi	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_5092234_7	1254432.SCE1572_37460	2.587e-24	106.0	COG0400@1|root,COG0400@2|Bacteria,1P51S@1224|Proteobacteria	1224|Proteobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
WXD1_k127_5106239_8	1175306.GWL_25620	1.214e-07	60.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VXH1@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WXD1_k127_5106239_2	509191.AEDB02000109_gene5106	1.374e-71	258.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,3WNBT@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
WXD1_k127_5106239_7	1133849.O3I_010600	7.618e-11	68.0	COG1959@1|root,COG1959@2|Bacteria,2IFQN@201174|Actinobacteria,4G0QM@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WXD1_k127_5106239_0	1328313.DS2_17878	3.61e-138	448.0	COG2010@1|root,COG2132@1|root,COG2010@2|Bacteria,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,1RXZF@1236|Gammaproteobacteria,46799@72275|Alteromonadaceae	1236|Gammaproteobacteria	CQ	Multicopper oxidase	nirK	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C,Cytochrome_CBB3
WXD1_k127_5106239_3	243365.CV_2008	1.891e-51	196.0	COG1262@1|root,COG1262@2|Bacteria,1RAP4@1224|Proteobacteria,2VNNP@28216|Betaproteobacteria,2KQB8@206351|Neisseriales	206351|Neisseriales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
WXD1_k127_5106239_4	861299.J421_0404	1.931e-37	150.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WXD1_k127_5106239_5	861299.J421_5726	6.019e-31	138.0	COG3047@1|root,COG3047@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
WXD1_k127_5106239_1	1265502.KB905954_gene415	1.253e-75	262.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VKTD@28216|Betaproteobacteria,4ABHT@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WXD1_k127_5106239_6	314225.ELI_11205	1.995e-18	86.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales	204457|Sphingomonadales	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WXD1_k127_513439_5	861299.J421_3401	1.691e-08	66.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WXD1_k127_513439_4	1536772.R70723_09900	1.965e-11	79.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WXD1_k127_513439_1	1500894.JQNN01000001_gene1202	8.401e-52	213.0	COG1361@1|root,COG1361@2|Bacteria,1QV4I@1224|Proteobacteria	1224|Proteobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WXD1_k127_513439_0	697282.Mettu_3211	2.154e-60	239.0	COG1361@1|root,COG1664@1|root,COG3210@1|root,COG1361@2|Bacteria,COG1664@2|Bacteria,COG3210@2|Bacteria,1PGPQ@1224|Proteobacteria,1S5UG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WXD1_k127_513439_3	1173028.ANKO01000132_gene1911	3.669e-17	97.0	COG4719@1|root,COG4719@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,FTP,Peptidase_M36,SdrD_B
WXD1_k127_513439_2	861299.J421_0768	7.924e-50	196.0	COG2234@1|root,COG2234@2|Bacteria,1ZT6Z@142182|Gemmatimonadetes	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WXD1_k127_5143858_15	379066.GAU_2077	0.0003341	44.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5143858_2	869210.Marky_1642	4.496e-208	655.0	COG3033@1|root,COG3033@2|Bacteria,1WM62@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WXD1_k127_5143858_6	373903.Hore_10260	1.546e-78	273.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,3WAA2@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WXD1_k127_5143858_13	573569.F7308_1220	7.6e-31	142.0	COG2503@1|root,COG2503@2|Bacteria,1RB4N@1224|Proteobacteria,1RY2I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Acid phosphatase	hel	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
WXD1_k127_5143858_9	1382359.JIAL01000001_gene1032	6.566e-60	233.0	COG1231@1|root,COG1231@2|Bacteria,3Y2HW@57723|Acidobacteria,2JIJJ@204432|Acidobacteriia	204432|Acidobacteriia	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WXD1_k127_5143858_7	518766.Rmar_2649	2.385e-67	233.0	COG4665@1|root,COG4665@2|Bacteria,4NTWB@976|Bacteroidetes,1FJET@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
WXD1_k127_5143858_3	518766.Rmar_2648	9.367e-194	621.0	COG4664@1|root,COG4664@2|Bacteria,4PM5T@976|Bacteroidetes,1FIK6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
WXD1_k127_5143858_8	365528.KB891219_gene1123	2.494e-60	223.0	COG1122@1|root,COG1122@2|Bacteria,2GJ0M@201174|Actinobacteria,4ERZ4@85013|Frankiales	201174|Actinobacteria	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
WXD1_k127_5143858_14	65393.PCC7424_2186	4.718e-15	89.0	COG0619@1|root,COG0619@2|Bacteria,1G2EM@1117|Cyanobacteria,3KGTD@43988|Cyanothece	1117|Cyanobacteria	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
WXD1_k127_5143858_12	56107.Cylst_3798	3.092e-51	195.0	COG0310@1|root,COG0310@2|Bacteria,1G40K@1117|Cyanobacteria,1HIGH@1161|Nostocales	1117|Cyanobacteria	P	PFAM Cobalt uptake substrate-specific transmembrane region	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
WXD1_k127_5143858_5	1330700.JQNC01000003_gene1827	3.294e-142	463.0	COG4663@1|root,COG4663@2|Bacteria,1WJ6R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
WXD1_k127_5143858_10	215803.DB30_3564	2.993e-56	217.0	COG1538@1|root,COG1538@2|Bacteria,1Q54P@1224|Proteobacteria,42NQV@68525|delta/epsilon subdivisions,2X5KQ@28221|Deltaproteobacteria,2YYUS@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WXD1_k127_5143858_11	187272.Mlg_0883	2.712e-51	197.0	COG0845@1|root,COG0845@2|Bacteria,1RD8U@1224|Proteobacteria,1S527@1236|Gammaproteobacteria,1WZ3Z@135613|Chromatiales	135613|Chromatiales	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WXD1_k127_5143858_0	1266914.ATUK01000011_gene2567	1.897e-321	1017.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,1WXV4@135613|Chromatiales	135613|Chromatiales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WXD1_k127_5143858_1	1499967.BAYZ01000118_gene3290	5.569e-213	684.0	COG0058@1|root,COG0058@2|Bacteria,2NNZS@2323|unclassified Bacteria	2|Bacteria	G	Carbohydrate phosphorylase	malP	-	2.4.1.1,2.4.1.8	ko:K00688,ko:K00691	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R01555,R02111	RC00049	ko00000,ko00001,ko01000	-	GH65,GT35	-	DUF3417,Phosphorylase
WXD1_k127_5143858_4	204669.Acid345_4566	1.035e-152	493.0	COG0192@1|root,COG0192@2|Bacteria,3Y45C@57723|Acidobacteria,2JJ0A@204432|Acidobacteriia	2|Bacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.metX	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WXD1_k127_51535_4	1379270.AUXF01000001_gene2301	1.299e-18	98.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1ZUF5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_51535_2	1379270.AUXF01000001_gene2302	1.675e-47	188.0	COG4249@1|root,COG4249@2|Bacteria,1ZUQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_51535_1	379066.GAU_3097	1.624e-191	622.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1ZUB1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
WXD1_k127_51535_3	1267535.KB906767_gene904	5.248e-47	185.0	2DBN7@1|root,2ZA2Y@2|Bacteria,3Y6N3@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
WXD1_k127_51535_0	861299.J421_4050	1.454e-227	734.0	COG5549@1|root,COG5549@2|Bacteria,1ZTC4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Domain of unknown function (DUF5118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
WXD1_k127_5157890_1	443144.GM21_1396	2.674e-91	313.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2WIPU@28221|Deltaproteobacteria,43UK1@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WXD1_k127_5157890_6	1379270.AUXF01000004_gene3107	2.538e-22	104.0	COG1522@1|root,COG1522@2|Bacteria,1ZU0G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
WXD1_k127_5157890_3	379066.GAU_0613	3.988e-62	227.0	COG0697@1|root,COG0697@2|Bacteria,1ZTNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WXD1_k127_5157890_4	452637.Oter_3829	2.772e-48	185.0	COG1524@1|root,COG1524@2|Bacteria,46VXF@74201|Verrucomicrobia,3K93S@414999|Opitutae	414999|Opitutae	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WXD1_k127_5157890_0	1047013.AQSP01000134_gene1353	0.0	1037.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WXD1_k127_5157890_2	861299.J421_2657	3.561e-84	306.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	2|Bacteria	N	domain, Protein	-	-	3.2.1.4,3.4.17.14	ko:K01179,ko:K07260,ko:K13735	ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100	M00651	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	GH5,GH9	-	Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH
WXD1_k127_5157890_7	1379270.AUXF01000003_gene3466	3.52e-13	79.0	2F8UF@1|root,3416F@2|Bacteria,1ZTX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_519148_7	861299.J421_2666	7.727e-20	91.0	COG0508@1|root,COG0508@2|Bacteria,1ZSYJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WXD1_k127_519148_1	395964.KE386496_gene790	2.313e-130	425.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,3N9PF@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
WXD1_k127_519148_2	861299.J421_2668	3.555e-119	395.0	COG1071@1|root,COG1071@2|Bacteria,1ZT5G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WXD1_k127_519148_3	379066.GAU_0751	5.547e-109	365.0	COG0320@1|root,COG0320@2|Bacteria,1ZTA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WXD1_k127_519148_5	266117.Rxyl_0724	2.943e-78	274.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4CQ48@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
WXD1_k127_519148_0	251221.35211608	2.339e-153	513.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
WXD1_k127_519148_4	1128421.JAGA01000001_gene2048	2.628e-90	306.0	COG1611@1|root,COG1611@2|Bacteria,2NP7M@2323|unclassified Bacteria	2|Bacteria	S	Possible lysine decarboxylase	yvdD_2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WXD1_k127_519148_6	861299.J421_0446	2.597e-36	147.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_519148_8	1210884.HG799465_gene11828	9.893e-06	50.0	COG2234@1|root,COG2234@2|Bacteria,2IWTP@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WXD1_k127_5200082_0	644966.Tmar_1638	3.862e-189	603.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WCWS@538999|Clostridiales incertae sedis	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WXD1_k127_5200082_1	1128421.JAGA01000002_gene903	5.852e-98	334.0	COG0182@1|root,COG0182@2|Bacteria,2NNM7@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
WXD1_k127_5200082_3	379066.GAU_2420	4.002e-64	229.0	COG0424@1|root,COG0424@2|Bacteria,1ZTP7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WXD1_k127_5200082_4	665952.HMPREF1015_00389	8.932e-52	189.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,1ZG82@1386|Bacillus	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WXD1_k127_5200082_2	861299.J421_5841	2.185e-65	232.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015,SusD-like_2
WXD1_k127_5204757_11	1278073.MYSTI_01803	5.438e-19	91.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	araC	-	-	ko:K21701	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding_2,HTH_18
WXD1_k127_5204757_12	485913.Krac_7553	6.116e-12	76.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
WXD1_k127_5204757_4	396588.Tgr7_1815	1.985e-52	194.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,1RMGB@1236|Gammaproteobacteria,1WWMW@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
WXD1_k127_5204757_9	926560.KE387025_gene4075	1.983e-29	130.0	2B5RU@1|root,31YMF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
WXD1_k127_5204757_13	1280680.AUJU01000046_gene1574	0.0001334	53.0	COG0348@1|root,COG0348@2|Bacteria,1V66G@1239|Firmicutes,25C0K@186801|Clostridia,4BWFS@830|Butyrivibrio	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
WXD1_k127_5204757_2	765420.OSCT_2998	6.292e-117	395.0	COG1251@1|root,COG1251@2|Bacteria,2G6YZ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Pyr_redox_2
WXD1_k127_5204757_10	765420.OSCT_2999	3.003e-24	111.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_oxidored,Pyr_redox_2,Thioredoxin_3,cNMP_binding
WXD1_k127_5204757_5	765420.OSCT_3000	1.238e-47	189.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
WXD1_k127_5204757_0	861299.J421_2179	8.405e-279	871.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WXD1_k127_5204757_3	323848.Nmul_A1256	1.014e-97	326.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,2VQ50@28216|Betaproteobacteria,37328@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c	norC	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
WXD1_k127_5204757_1	323848.Nmul_A1255	7.214e-191	606.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,2VHXU@28216|Betaproteobacteria,371TN@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c oxidase, subunit I	norB	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
WXD1_k127_5204757_7	1122604.JONR01000042_gene3451	3.627e-34	138.0	2EBUX@1|root,335UE@2|Bacteria,1NAYE@1224|Proteobacteria,1T8Q1@1236|Gammaproteobacteria,1XB2A@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5204757_6	861299.J421_0408	6.236e-45	169.0	2E3MN@1|root,32NV6@2|Bacteria,1ZV65@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
WXD1_k127_5214694_5	861299.J421_2919	1.913e-21	103.0	COG1629@1|root,COG1629@2|Bacteria,1ZTI4@142182|Gemmatimonadetes	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Caps_assemb_Wzi
WXD1_k127_5214694_1	502025.Hoch_4956	4.967e-93	318.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2YU7R@29|Myxococcales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WXD1_k127_5214694_4	379066.GAU_3093	1.995e-38	152.0	COG1309@1|root,COG1309@2|Bacteria,1ZTWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WXD1_k127_5214694_2	379066.GAU_3092	8.311e-93	331.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WXD1_k127_5214694_3	861299.J421_2016	9.772e-80	293.0	COG0845@1|root,COG0845@2|Bacteria,1ZSR2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WXD1_k127_5214694_0	1144275.COCOR_00464	3.935e-292	919.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YX1A@29|Myxococcales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
WXD1_k127_5225343_3	1379270.AUXF01000003_gene3429	3.259e-32	133.0	COG0711@1|root,COG0711@2|Bacteria,1ZTPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
WXD1_k127_5225343_2	861299.J421_3944	1.524e-42	162.0	COG0712@1|root,COG0712@2|Bacteria,1ZTP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
WXD1_k127_5225343_0	246194.CHY_2547	6.694e-213	673.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,42F4E@68295|Thermoanaerobacterales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WXD1_k127_5225343_1	861299.J421_2628	6.103e-108	357.0	COG0224@1|root,COG0224@2|Bacteria,1ZSZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WXD1_k127_5225343_4	861299.J421_2629	2.031e-17	83.0	COG0055@1|root,COG0055@2|Bacteria,1ZSNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WXD1_k127_5225867_0	379066.GAU_3308	4.106e-147	473.0	COG2234@1|root,COG2234@2|Bacteria,1ZTDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WXD1_k127_5225867_3	861299.J421_2573	3.459e-33	139.0	2DPS4@1|root,3335F@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
WXD1_k127_5225867_1	861299.J421_2931	5.957e-92	328.0	28I3N@1|root,2Z87C@2|Bacteria,1ZT9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
WXD1_k127_5225867_2	518766.Rmar_0728	3.324e-62	225.0	COG2885@1|root,COG2885@2|Bacteria,4NEGF@976|Bacteroidetes,1FJ6B@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA,PD40
WXD1_k127_5273828_0	696369.KI912183_gene1835	1.268e-155	504.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,2612J@186807|Peptococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WXD1_k127_5273828_4	443144.GM21_2624	1.388e-08	67.0	2DST5@1|root,33HC3@2|Bacteria,1NMTA@1224|Proteobacteria,42XYN@68525|delta/epsilon subdivisions,2WT9U@28221|Deltaproteobacteria,43VXG@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5273828_3	1125863.JAFN01000001_gene2642	3.99e-17	85.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1N3ZM@1224|Proteobacteria,42TUU@68525|delta/epsilon subdivisions,2WQ8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KP	PFAM iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
WXD1_k127_5273828_1	797304.Natgr_0465	2.494e-107	363.0	COG1232@1|root,arCOG01522@2157|Archaea,2XT3Z@28890|Euryarchaeota,23TW5@183963|Halobacteria	183963|Halobacteria	H	protoporphyrinogen oxidase	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
WXD1_k127_5273828_2	570967.JMLV01000006_gene206	2.46e-22	101.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
WXD1_k127_5275227_0	402626.Rpic_3836	8.66e-194	616.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,1K23H@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Amp-dependent synthetase and ligase	bclA_1	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
WXD1_k127_5275227_4	316055.RPE_3226	8.655e-33	131.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria,3JYDU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WXD1_k127_5275227_3	861299.J421_6160	1.546e-45	189.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_6160|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WXD1_k127_5275227_6	754035.Mesau_01984	3.343e-09	70.0	COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_16,TPR_8,Trans_reg_C
WXD1_k127_5275227_2	379066.GAU_0693	7.276e-110	371.0	COG3876@1|root,COG3876@2|Bacteria	2|Bacteria	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
WXD1_k127_5275227_5	187303.BN69_0571	1.568e-28	126.0	arCOG06832@1|root,31H39@2|Bacteria,1RJBH@1224|Proteobacteria,2U9PE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WXD1_k127_5275227_1	861299.J421_1737	5.031e-125	404.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	iSbBS512_1146.SbBS512_E2507	GSDH
WXD1_k127_5278265_2	861299.J421_1236	4.36e-48	179.0	COG0488@1|root,COG0488@2|Bacteria,1ZSV1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
WXD1_k127_5278265_1	861299.J421_3846	3.024e-66	231.0	COG1392@1|root,COG1392@2|Bacteria,1ZTKX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
WXD1_k127_5278265_0	1379270.AUXF01000003_gene3559	6.202e-146	471.0	COG0306@1|root,COG0306@2|Bacteria,1ZSZ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
WXD1_k127_5292307_1	671143.DAMO_3032	3.938e-99	329.0	COG0861@1|root,COG0861@2|Bacteria,2NQFQ@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
WXD1_k127_5292307_0	379066.GAU_0052	4.246e-296	932.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
WXD1_k127_5292307_2	861299.J421_6223	3.694e-65	230.0	COG2091@1|root,COG2091@2|Bacteria,1ZUE3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5314128_6	861299.J421_0175	4.74e-14	75.0	COG2204@1|root,COG2204@2|Bacteria,1ZTDN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_5314128_8	861299.J421_0181	1.273e-09	65.0	COG1815@1|root,COG1815@2|Bacteria,1ZU3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	bacterial-type flagellum-dependent cell motility	-	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	-
WXD1_k127_5314128_3	379066.GAU_0334	1.322e-31	135.0	COG1558@1|root,COG1558@2|Bacteria,1ZTTB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Flagella basal body rod protein	-	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WXD1_k127_5314128_9	379066.GAU_0333	1.232e-06	60.0	298E4@1|root,2ZVJB@2|Bacteria,1ZU20@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5314128_5	861299.J421_0184	1.657e-15	84.0	COG1677@1|root,COG1677@2|Bacteria,1ZU54@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
WXD1_k127_5314128_2	861299.J421_0185	6.09e-93	322.0	COG1766@1|root,COG1766@2|Bacteria,1ZT4R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	The M ring may be actively involved in energy transduction	-	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
WXD1_k127_5314128_1	1379270.AUXF01000002_gene1663	6.225e-112	371.0	COG1536@1|root,COG1536@2|Bacteria,1ZTEY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	FliG N-terminal domain	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
WXD1_k127_5314128_4	861299.J421_0187	3.336e-21	101.0	COG1317@1|root,COG1317@2|Bacteria,1ZTXY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
WXD1_k127_5314128_0	861299.J421_0188	7.558e-184	584.0	COG1157@1|root,COG1157@2|Bacteria,1ZSTA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	ATP synthase alpha/beta family, beta-barrel domain	-	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WXD1_k127_5314128_7	1379270.AUXF01000002_gene1660	4.126e-12	78.0	2CIX0@1|root,2ZTZA@2|Bacteria,1ZU6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Flagellar FliJ protein	-	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
WXD1_k127_5337194_0	861299.J421_1322	1.844e-138	453.0	COG0165@1|root,COG0165@2|Bacteria,1ZSM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
WXD1_k127_5337194_10	1379270.AUXF01000001_gene2791	3.182e-07	60.0	2FK78@1|root,34BUZ@2|Bacteria,1ZU15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5337194_4	867903.ThesuDRAFT_00954	3.81e-107	355.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3WCW3@538999|Clostridiales incertae sedis	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
WXD1_k127_5337194_3	867903.ThesuDRAFT_00953	2.113e-120	396.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3WCWW@538999|Clostridiales incertae sedis	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WXD1_k127_5337194_8	4006.Lus10042951	3.914e-58	223.0	COG0120@1|root,KOG3075@2759|Eukaryota,37KM9@33090|Viridiplantae,3GB4J@35493|Streptophyta,4JNEE@91835|fabids	35493|Streptophyta	G	Ribose-5-phosphate isomerase	-	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007275,GO:0008150,GO:0008219,GO:0009791,GO:0009987,GO:0010228,GO:0016853,GO:0016860,GO:0016861,GO:0022414,GO:0032501,GO:0032502,GO:0044424,GO:0044464,GO:0048608,GO:0048731,GO:0048856,GO:0061458	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
WXD1_k127_5337194_1	1027273.GZ77_21585	9.284e-123	401.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RPMI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Aldolase	fda	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
WXD1_k127_5337194_6	1408254.T458_17235	1.772e-79	273.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli,26Q92@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WXD1_k127_5337194_9	414684.RC1_0774	4.018e-53	203.0	COG2120@1|root,COG2120@2|Bacteria,1RJX0@1224|Proteobacteria,2UA4M@28211|Alphaproteobacteria,2JXQF@204441|Rhodospirillales	204441|Rhodospirillales	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WXD1_k127_5337194_5	1173024.KI912151_gene1921	2.179e-82	299.0	COG4299@1|root,COG4299@2|Bacteria,1G4GE@1117|Cyanobacteria,1JJQE@1189|Stigonemataceae	1117|Cyanobacteria	S	Domain of unknown function (DUF5009)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
WXD1_k127_5337194_2	342113.DM82_745	1.99e-121	423.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,2VHGG@28216|Betaproteobacteria,1K3H2@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glycos_transf_2,PilZ
WXD1_k127_5337194_7	1173026.Glo7428_3604	1.354e-66	243.0	COG3170@1|root,COG3170@2|Bacteria,1GQ34@1117|Cyanobacteria	1117|Cyanobacteria	NU	Protein of unknown function (DUF3131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3131
WXD1_k127_5356148_0	761193.Runsl_2487	0.0	1282.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WXD1_k127_5356148_19	1167006.UWK_01364	2.122e-09	69.0	2BCS0@1|root,303C3@2|Bacteria,1N7SU@1224|Proteobacteria,42WF2@68525|delta/epsilon subdivisions,2WR6I@28221|Deltaproteobacteria,2MNJG@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
WXD1_k127_5356148_4	861299.J421_1447	8.943e-101	334.0	COG4108@1|root,COG4108@2|Bacteria,1ZSMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
WXD1_k127_5356148_3	861299.J421_1447	4.521e-114	374.0	COG4108@1|root,COG4108@2|Bacteria,1ZSMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
WXD1_k127_5356148_18	502025.Hoch_5735	1.263e-13	84.0	29FS0@1|root,302PP@2|Bacteria,1RE1Q@1224|Proteobacteria,4383H@68525|delta/epsilon subdivisions,2X3DF@28221|Deltaproteobacteria,2YVJ0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5356148_13	1379270.AUXF01000001_gene2219	1.094e-39	155.0	COG2771@1|root,COG2771@2|Bacteria	2|Bacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WXD1_k127_5356148_16	1089550.ATTH01000001_gene1357	5.521e-25	120.0	2BQ96@1|root,32J40@2|Bacteria,4PETN@976|Bacteroidetes,1FJKR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
WXD1_k127_5356148_21	1385518.N798_01075	1.803e-05	58.0	COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria,4FGS5@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
WXD1_k127_5356148_12	1476583.DEIPH_ctg046orf0046	7.075e-45	166.0	COG1145@1|root,32SB1@2|Bacteria,1WN0M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5356148_15	1120999.JONM01000001_gene1192	3.354e-32	138.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,TPR_12,Trans_reg_C
WXD1_k127_5356148_1	1408254.T458_24110	1.952e-152	491.0	COG1914@1|root,COG1914@2|Bacteria,1TP0Q@1239|Firmicutes,4HAYE@91061|Bacilli,271IU@186822|Paenibacillaceae	91061|Bacilli	P	Natural resistance-associated macrophage protein	ycsG	-	-	-	-	-	-	-	-	-	-	-	Nramp
WXD1_k127_5356148_6	1122919.KB905556_gene1016	1.216e-83	299.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,4H9PF@91061|Bacilli,26QYJ@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the UPF0271 (lamB) family	ycsF	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
WXD1_k127_5356148_7	649747.HMPREF0083_03113	7.453e-82	295.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,26SC6@186822|Paenibacillaceae	91061|Bacilli	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
WXD1_k127_5356148_10	1382304.JNIL01000001_gene3301	8.078e-65	228.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4HHJJ@91061|Bacilli,278U6@186823|Alicyclobacillaceae	91061|Bacilli	E	Allophanate hydrolase subunit 1	kipI	-	-	ko:K06351	-	-	-	-	ko00000	-	-	-	CT_C_D
WXD1_k127_5356148_20	379066.GAU_2612	6.183e-07	58.0	2AUA7@1|root,31JXQ@2|Bacteria,1ZV7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5356148_2	1379270.AUXF01000001_gene1895	7.696e-122	400.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WXD1_k127_5356148_9	102129.Lepto7375DRAFT_1869	5.5e-67	240.0	COG2860@1|root,COG2860@2|Bacteria,1GD1U@1117|Cyanobacteria	1117|Cyanobacteria	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
WXD1_k127_5356148_14	1195236.CTER_5081	1.289e-33	136.0	2D5AS@1|root,32TIN@2|Bacteria,1VA4E@1239|Firmicutes,24JJQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5356148_22	96561.Dole_0109	5.434e-05	54.0	2BCS0@1|root,303C3@2|Bacteria,1N7SU@1224|Proteobacteria,42WF2@68525|delta/epsilon subdivisions,2WR6I@28221|Deltaproteobacteria,2MNJG@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
WXD1_k127_5356148_8	426355.Mrad2831_5329	2.822e-69	262.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,1JRWQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
WXD1_k127_5356148_5	1122604.JONR01000042_gene3484	4.541e-97	331.0	COG1723@1|root,COG1723@2|Bacteria,1R8R9@1224|Proteobacteria,1SKCB@1236|Gammaproteobacteria,1X53E@135614|Xanthomonadales	135614|Xanthomonadales	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5356148_17	42256.RradSPS_1028	4.535e-21	93.0	COG2406@1|root,COG2406@2|Bacteria,2HPQS@201174|Actinobacteria,4CR3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Rubrerythrin	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
WXD1_k127_5372251_2	861299.J421_6160	1.085e-96	339.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_6160|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WXD1_k127_5372251_0	1144275.COCOR_07655	1.675e-238	754.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
WXD1_k127_5372251_1	404589.Anae109_1629	2.233e-130	427.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
WXD1_k127_5380216_2	861299.J421_3444	2.413e-166	546.0	COG0072@1|root,COG0072@2|Bacteria,1ZSWJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WXD1_k127_5380216_12	861299.J421_3442	1.116e-14	81.0	COG3027@1|root,COG3027@2|Bacteria,1ZU4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
WXD1_k127_5380216_1	861299.J421_3441	5.057e-180	578.0	COG1418@1|root,COG1418@2|Bacteria,1ZT0I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WXD1_k127_5380216_6	589865.DaAHT2_0828	2.259e-102	341.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,2MHRX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WXD1_k127_5380216_7	861299.J421_3439	1.774e-97	334.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WXD1_k127_5380216_10	379066.GAU_1867	2.809e-71	252.0	COG0142@1|root,COG0142@2|Bacteria,1ZSR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WXD1_k127_5380216_0	379066.GAU_1866	1.784e-241	761.0	COG1154@1|root,COG1154@2|Bacteria,1ZSP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
WXD1_k127_5380216_9	861299.J421_3435	3.921e-72	257.0	COG0061@1|root,COG0061@2|Bacteria,1ZT32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WXD1_k127_5380216_4	861299.J421_3434	1.09e-155	508.0	COG0497@1|root,COG0497@2|Bacteria,1ZSV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
WXD1_k127_5380216_8	861299.J421_3108	1.648e-90	312.0	2F044@1|root,33T7T@2|Bacteria,1ZTDC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5380216_3	379066.GAU_1920	2.506e-165	554.0	COG1629@1|root,COG4771@2|Bacteria,1ZST4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CarboxypepD_reg-like domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
WXD1_k127_5380216_11	379066.GAU_1862	2.977e-64	246.0	COG3538@1|root,COG3538@2|Bacteria,1ZTCY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal-independent alpha-mannosidase (GH125)	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5380216_5	404589.Anae109_0139	2.85e-103	354.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WXD1_k127_5380216_13	1211814.CAPG01000082_gene3799	2.3e-05	51.0	2BF4Y@1|root,328X8@2|Bacteria,1UB8H@1239|Firmicutes,4IMM8@91061|Bacilli,1ZKEI@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5384381_1	861299.J421_1545	1.026e-25	119.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	BTAD
WXD1_k127_5384381_0	479434.Sthe_2691	7.577e-319	989.0	COG1523@1|root,COG1523@2|Bacteria,2G86B@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
WXD1_k127_5387877_7	452637.Oter_2330	1.507e-37	155.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
WXD1_k127_5387877_5	1254432.SCE1572_26550	2.069e-55	203.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,42RCM@68525|delta/epsilon subdivisions,2WN89@28221|Deltaproteobacteria,2YVX5@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
WXD1_k127_5387877_6	313596.RB2501_11927	1.546e-45	181.0	COG0457@1|root,COG0457@2|Bacteria,4NQR8@976|Bacteroidetes,1I0ZH@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2911)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2911
WXD1_k127_5387877_4	518766.Rmar_1813	4.181e-109	369.0	COG0366@1|root,COG0366@2|Bacteria,4NEVK@976|Bacteroidetes,1FIXN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WXD1_k127_5387877_2	861299.J421_6266	2.711e-213	676.0	COG2211@1|root,COG2211@2|Bacteria,1ZUJ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	MFS/sugar transport protein	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
WXD1_k127_5387877_3	861299.J421_4128	2.82e-184	590.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	iLJ478.TM1840	Alpha-amylase,DUF1945,DUF3459
WXD1_k127_5387877_0	861299.J421_6259	1.699e-297	924.0	COG0366@1|root,COG0366@2|Bacteria,1ZUGN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Cyclomaltodextrinase, N-terminal	-	-	3.2.1.135	ko:K21575	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase,Cyc-maltodext_N
WXD1_k127_5387877_1	1379270.AUXF01000003_gene3768	2.679e-276	861.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
WXD1_k127_5403480_7	926560.KE387025_gene4023	3.666e-56	211.0	COG1215@1|root,COG1215@2|Bacteria,1WIG8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
WXD1_k127_5403480_10	518766.Rmar_1599	1.5e-42	165.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WXD1_k127_5403480_6	861299.J421_1840	1.053e-62	243.0	COG1562@1|root,COG1562@2|Bacteria,1ZU4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WXD1_k127_5403480_5	518766.Rmar_1601	2.165e-71	251.0	COG1562@1|root,COG2324@1|root,COG1562@2|Bacteria,COG2324@2|Bacteria,4PERW@976|Bacteroidetes,1FJHM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WXD1_k127_5403480_8	861299.J421_1842	6.167e-56	208.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	litR	-	2.3.3.1	ko:K01647,ko:K22491	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WXD1_k127_5403480_1	861299.J421_1843	2.667e-224	706.0	COG1233@1|root,COG1233@2|Bacteria,1ZSTQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
WXD1_k127_5403480_9	649638.Trad_2243	2.74e-54	208.0	COG0204@1|root,COG2324@1|root,COG0204@2|Bacteria,COG2324@2|Bacteria,1WI4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM lycopene cyclase domain	-	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
WXD1_k127_5403480_0	649638.Trad_2244	5.902e-243	768.0	COG1233@1|root,COG1233@2|Bacteria,1WJJE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WXD1_k127_5403480_4	1382358.JHVN01000006_gene165	1.9e-91	312.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1TQX3@1239|Firmicutes,4HCI6@91061|Bacilli,21V7U@150247|Anoxybacillus	91061|Bacilli	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
WXD1_k127_5403480_3	604331.AUHY01000008_gene439	3.154e-135	445.0	COG0415@1|root,COG0415@2|Bacteria,1WIIZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	DNA photolyase	ung	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7,UDG
WXD1_k127_5403480_11	748247.AZKH_3363	5.635e-11	65.0	COG2331@1|root,COG2331@2|Bacteria,1NMRY@1224|Proteobacteria,2W531@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WXD1_k127_5403480_2	471853.Bcav_2287	1.038e-202	679.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WXD1_k127_5403480_12	195250.CM001776_gene3778	2.812e-05	46.0	COG3547@1|root,COG3547@2|Bacteria,1G1N1@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase is116 is110 is902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
WXD1_k127_5406011_0	1379270.AUXF01000006_gene180	1.955e-122	401.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WXD1_k127_5406011_1	861299.J421_3350	1.181e-117	389.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
WXD1_k127_5406011_2	1499967.BAYZ01000027_gene1809	1.411e-29	127.0	COG0661@1|root,COG0661@2|Bacteria	2|Bacteria	I	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	aarF	-	-	-	-	-	-	-	-	-	-	-	ABC1
WXD1_k127_5416535_19	414684.RC1_0497	2.698e-07	61.0	2E4S1@1|root,32ZKH@2|Bacteria,1N9PR@1224|Proteobacteria,2UFAW@28211|Alphaproteobacteria,2JTZW@204441|Rhodospirillales	204441|Rhodospirillales	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
WXD1_k127_5416535_18	1211815.CBYP010000007_gene337	1.856e-15	90.0	COG1266@1|root,COG1266@2|Bacteria,2IS6T@201174|Actinobacteria	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WXD1_k127_5416535_10	861299.J421_0797	3.013e-51	192.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	dgkA	-	2.7.1.107,3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K00901,ko:K01096,ko:K19302	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02029,R02240,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_2369	DAGK_prokar,PAP2,PAP2_3
WXD1_k127_5416535_5	483219.LILAB_26910	6.196e-108	361.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5416535_2	861299.J421_0795	3.223e-163	522.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	2|Bacteria	H	Beta-eliminating lyase	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WXD1_k127_5416535_9	880073.Calab_3788	3.815e-57	213.0	COG0451@1|root,COG0451@2|Bacteria,2NPC7@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WXD1_k127_5416535_6	502025.Hoch_0564	6.727e-99	338.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YWB2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WXD1_k127_5416535_8	13689.BV96_00847	2.592e-70	252.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U2WH@28211|Alphaproteobacteria,2KCB6@204457|Sphingomonadales	204457|Sphingomonadales	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
WXD1_k127_5416535_11	644966.Tmar_0122	7.59e-51	194.0	COG2096@1|root,COG2096@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia	186801|Clostridia	S	ATP cob(I)alamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
WXD1_k127_5416535_14	324602.Caur_1553	1.699e-38	146.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi,375SD@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
WXD1_k127_5416535_16	1382359.JIAL01000001_gene1751	2.289e-21	102.0	COG4319@1|root,COG4319@2|Bacteria,3Y5BE@57723|Acidobacteria,2JJS4@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
WXD1_k127_5416535_0	861299.J421_4478	1.333e-195	624.0	COG1574@1|root,COG1574@2|Bacteria,1ZU9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WXD1_k127_5416535_13	670487.Ocepr_1594	3.523e-40	156.0	COG1225@1|root,COG1225@2|Bacteria,1WKA8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WXD1_k127_5416535_3	1379270.AUXF01000001_gene2466	4.753e-156	507.0	COG0183@1|root,COG0183@2|Bacteria,1ZSW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
WXD1_k127_5416535_15	1341151.ASZU01000014_gene2173	7.298e-25	119.0	COG4552@1|root,COG4552@2|Bacteria,1U5C4@1239|Firmicutes,4HF2I@91061|Bacilli	91061|Bacilli	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
WXD1_k127_5416535_12	169963.lmo2412	1.187e-44	167.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,26JTS@186820|Listeriaceae	91061|Bacilli	C	Nitrogen fixation protein NifU	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WXD1_k127_5416535_1	243231.GSU0892	1.874e-165	545.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43UGC@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WXD1_k127_5416535_4	765420.OSCT_1487	4.778e-155	501.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi,3766K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
WXD1_k127_5416535_17	1120936.KB907219_gene3139	3.235e-21	101.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4EK27@85012|Streptosporangiales	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	sufE	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
WXD1_k127_5416535_7	266117.Rxyl_0168	5.608e-87	295.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
WXD1_k127_5435878_19	748247.AZKH_2018	1.004e-10	63.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VHQ9@28216|Betaproteobacteria,2KXZ0@206389|Rhodocyclales	206389|Rhodocyclales	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
WXD1_k127_5435878_11	671143.DAMO_1688	1.738e-36	152.0	COG3278@1|root,COG3278@2|Bacteria,2NRHY@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5435878_17	1033743.CAES01000045_gene206	3.493e-17	92.0	COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli,26Z9P@186822|Paenibacillaceae	91061|Bacilli	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
WXD1_k127_5435878_12	671143.DAMO_1689	1.038e-30	130.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
WXD1_k127_5435878_13	518766.Rmar_2295	1.047e-30	124.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249,Hemerythrin
WXD1_k127_5435878_15	518766.Rmar_2292	3.624e-21	100.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
WXD1_k127_5435878_16	215803.DB30_2479	1.311e-20	101.0	2C5K3@1|root,344B2@2|Bacteria,1QMRP@1224|Proteobacteria,43E9X@68525|delta/epsilon subdivisions,2X8WK@28221|Deltaproteobacteria,2Z0QP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5435878_2	861299.J421_3027	4.465e-167	545.0	COG1649@1|root,COG1649@2|Bacteria,1ZSWQ@142182|Gemmatimonadetes	2|Bacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
WXD1_k127_5435878_10	861299.J421_1903	2.404e-58	223.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1903|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5435878_8	861299.J421_0823	1.17e-93	319.0	COG2514@1|root,COG2514@2|Bacteria,1ZTDT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
WXD1_k127_5435878_20	1267533.KB906738_gene2224	3.721e-06	53.0	COG1918@1|root,COG1918@2|Bacteria,3Y92B@57723|Acidobacteria,2JNUD@204432|Acidobacteriia	204432|Acidobacteriia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
WXD1_k127_5435878_0	1340493.JNIF01000003_gene4353	3.6e-210	671.0	COG0370@1|root,COG0370@2|Bacteria,3Y3CZ@57723|Acidobacteria	57723|Acidobacteria	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WXD1_k127_5435878_3	1038858.AXBA01000006_gene893	2.805e-133	433.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,3F1HK@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WXD1_k127_5435878_6	861299.J421_0323	8.509e-113	374.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
WXD1_k127_5435878_9	1411123.JQNH01000001_gene2275	3.29e-64	226.0	COG2755@1|root,COG2755@2|Bacteria,1RBMS@1224|Proteobacteria,2U6E0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WXD1_k127_5435878_5	1267535.KB906767_gene1984	3.712e-113	372.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
WXD1_k127_5435878_7	1128421.JAGA01000002_gene1518	3.775e-102	339.0	COG3483@1|root,COG3483@2|Bacteria	2|Bacteria	E	tryptophan 2,3-dioxygenase activity	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
WXD1_k127_5435878_14	379066.GAU_2186	1.636e-30	121.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WXD1_k127_5435878_1	497964.CfE428DRAFT_1973	7.84e-186	598.0	COG1488@1|root,COG1488@2|Bacteria,46SAG@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
WXD1_k127_5435878_4	1379270.AUXF01000007_gene888	2.679e-119	416.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WXD1_k127_5450492_0	1267533.KB906734_gene3692	9.258e-16	89.0	COG2010@1|root,COG2010@2|Bacteria,3Y650@57723|Acidobacteria,2JKDC@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_CBB3,Paired_CXXCH_1
WXD1_k127_5450492_1	234267.Acid_6614	2.278e-08	66.0	2EZW8@1|root,33T0M@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
WXD1_k127_5459713_3	861299.J421_3216	1.926e-121	405.0	COG3869@1|root,COG3869@2|Bacteria,1ZT9I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP:guanido phosphotransferase, C-terminal catalytic domain	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
WXD1_k127_5459713_7	379066.GAU_1582	1.076e-38	150.0	COG3880@1|root,COG3880@2|Bacteria,1ZTPQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
WXD1_k127_5459713_6	1379270.AUXF01000006_gene307	1.926e-73	255.0	COG1136@1|root,COG1136@2|Bacteria,1ZSNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WXD1_k127_5459713_4	1379270.AUXF01000006_gene308	2.954e-88	316.0	COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WXD1_k127_5459713_1	264732.Moth_0152	9.739e-161	531.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
WXD1_k127_5459713_2	861299.J421_3211	1.536e-134	436.0	COG1186@1|root,COG1186@2|Bacteria,1ZTE4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WXD1_k127_5459713_9	861299.J421_3210	2.711e-33	134.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
WXD1_k127_5459713_5	379066.GAU_1576	2.196e-82	302.0	COG2199@1|root,COG2199@2|Bacteria,1ZT1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WXD1_k127_5459713_0	649747.HMPREF0083_00816	1.104e-177	582.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli,26R57@186822|Paenibacillaceae	91061|Bacilli	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WXD1_k127_5459713_10	861299.J421_3208	6.128e-30	134.0	2BXP0@1|root,34268@2|Bacteria,1ZTVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5459713_8	1379270.AUXF01000006_gene314	6.36e-34	141.0	COG1159@1|root,COG1159@2|Bacteria,1ZU0Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5465432_2	379066.GAU_1316	1.483e-93	323.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
WXD1_k127_5465432_1	379066.GAU_1315	1.045e-100	353.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cebB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4,YtkA
WXD1_k127_5465432_0	379066.GAU_1314	0.0	1374.0	COG3696@1|root,COG3696@2|Bacteria,1ZUB0@142182|Gemmatimonadetes	2|Bacteria	P	AcrB/AcrD/AcrF family	cusA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
WXD1_k127_5487379_0	886293.Sinac_3357	2.625e-157	506.0	COG1252@1|root,COG1252@2|Bacteria,2IXBA@203682|Planctomycetes	203682|Planctomycetes	C	NADH dehydrogenase, FAD-containing subunit	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WXD1_k127_5487379_1	1379270.AUXF01000004_gene2995	1.191e-18	94.0	COG2839@1|root,COG2839@2|Bacteria,1ZUVE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
WXD1_k127_5487379_2	1123072.AUDH01000001_gene3042	5.303e-06	59.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2JQVG@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WXD1_k127_5507436_0	945713.IALB_0006	8.119e-148	487.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WXD1_k127_5507436_2	765420.OSCT_0991	6.399e-62	224.0	COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi,377CS@32061|Chloroflexia	32061|Chloroflexia	S	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WXD1_k127_5507436_3	243274.THEMA_02235	4.65e-24	108.0	COG2151@1|root,COG2151@2|Bacteria,2GDA3@200918|Thermotogae	200918|Thermotogae	S	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
WXD1_k127_5507436_1	517418.Ctha_1772	5.184e-130	442.0	COG2203@1|root,COG2206@1|root,COG3437@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	GAF,GerE,HATPase_c,HD,HD_5,HisKA,PAS_4,PAS_9
WXD1_k127_5559674_0	861299.J421_1190	2.804e-308	962.0	COG1629@1|root,COG1629@2|Bacteria,1ZVAV@142182|Gemmatimonadetes	2|Bacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_5559674_4	861299.J421_1198	6.425e-107	380.0	2DB8U@1|root,2Z7SW@2|Bacteria	2|Bacteria	S	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
WXD1_k127_5559674_5	861299.J421_1199	1.019e-102	367.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
WXD1_k127_5559674_7	861299.J421_1195	5.187e-37	148.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	kdgF	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WXD1_k127_5559674_3	935837.JAEK01000019_gene755	3.951e-111	399.0	COG3250@1|root,COG4677@1|root,COG3250@2|Bacteria,COG4677@2|Bacteria,1TSCD@1239|Firmicutes,4HTSP@91061|Bacilli,1ZCC1@1386|Bacillus	91061|Bacilli	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pec_lyase,Pectinesterase
WXD1_k127_5559674_1	518766.Rmar_2391	4.875e-206	651.0	COG5434@1|root,COG5434@2|Bacteria,4NEM8@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Glyco_hydro_88,Pectate_lyase_3
WXD1_k127_5559674_8	861299.J421_6242	5.946e-30	125.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,STN,TonB_dep_Rec
WXD1_k127_5559674_2	518766.Rmar_2470	5.216e-150	494.0	COG4225@1|root,COG4225@2|Bacteria,4NFWI@976|Bacteroidetes	976|Bacteroidetes	V	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
WXD1_k127_5559674_6	861299.J421_0368	9.76e-68	236.0	COG4677@1|root,COG4677@2|Bacteria	2|Bacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861
WXD1_k127_5569086_3	861299.J421_3532	4.148e-37	155.0	COG2045@1|root,COG2045@2|Bacteria,1ZTM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
WXD1_k127_5569086_2	861299.J421_3533	1.527e-177	574.0	COG0439@1|root,COG0439@2|Bacteria,1ZT0Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WXD1_k127_5569086_0	379066.GAU_1783	1.289e-255	799.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WXD1_k127_5569086_1	379066.GAU_1789	5.265e-190	601.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WXD1_k127_5569137_1	861299.J421_1737	3.767e-96	325.0	COG2133@1|root,COG2133@2|Bacteria,1ZT6K@142182|Gemmatimonadetes	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	yliI	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	iSbBS512_1146.SbBS512_E2507	GSDH
WXD1_k127_5569137_0	1163409.UUA_04753	9.243e-113	373.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,1S0CZ@1236|Gammaproteobacteria,1X55D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
WXD1_k127_5575225_0	1144275.COCOR_07372	2.865e-221	698.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
WXD1_k127_5575225_9	1278073.MYSTI_05802	2.202e-47	175.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WSF5@28221|Deltaproteobacteria,2Z0Q9@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c nitrite reductase	-	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
WXD1_k127_5575225_13	1131269.AQVV01000013_gene1739	3.701e-26	123.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	oprD	-	-	ko:K08720,ko:K18093	ko01501,ko02020,ko05111,map01501,map02020,map05111	M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	1.B.1.2.1,1.B.25.1.1	-	iJN746.PP_1206	Alginate_exp,BBP2,OprD,Porin_4
WXD1_k127_5575225_7	1128421.JAGA01000004_gene2695	1.493e-57	207.0	COG2364@1|root,COG2364@2|Bacteria,2NRB7@2323|unclassified Bacteria	2|Bacteria	S	Membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
WXD1_k127_5575225_10	1278073.MYSTI_03219	5.5e-43	173.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_5575225_4	861299.J421_0282	7.629e-95	332.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_5575225_1	234267.Acid_2214	3.855e-170	562.0	COG0577@1|root,COG0577@2|Bacteria,3Y6B8@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_5575225_12	861299.J421_0552	2.075e-28	123.0	2DMJE@1|root,32RYR@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
WXD1_k127_5575225_5	1183438.GKIL_3624	4.219e-79	280.0	COG1073@1|root,COG1073@2|Bacteria,1GAUD@1117|Cyanobacteria	1117|Cyanobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
WXD1_k127_5575225_14	290317.Cpha266_1695	3.838e-06	54.0	COG2771@1|root,COG2771@2|Bacteria	2|Bacteria	K	luxR family	-	-	-	ko:K21405	-	-	-	-	ko00000,ko03000	-	-	-	DUF4019,GerE
WXD1_k127_5575225_8	469383.Cwoe_2995	3.979e-49	190.0	COG0566@1|root,COG0566@2|Bacteria,2GJ7P@201174|Actinobacteria	201174|Actinobacteria	J	SpoU rRNA Methylase family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
WXD1_k127_5575225_3	1123508.JH636446_gene6369	4.338e-141	478.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_5575225_2	1379270.AUXF01000002_gene1390	7.094e-150	524.0	COG1629@1|root,COG4771@2|Bacteria,1ZT7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WXD1_k127_5575225_6	886293.Sinac_1864	3.508e-60	229.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WXD1_k127_5575225_11	1379270.AUXF01000005_gene622	4.389e-31	123.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WXD1_k127_5585818_0	1415780.JPOG01000001_gene961	1.702e-99	347.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,1X78Y@135614|Xanthomonadales	135614|Xanthomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WXD1_k127_5585818_1	861299.J421_6079	2.666e-66	237.0	COG4242@1|root,COG4242@2|Bacteria,1ZUD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	PQ	Peptidase family S51	-	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
WXD1_k127_5586686_1	861299.J421_1451	4.419e-74	262.0	COG0661@1|root,COG0661@2|Bacteria,1ZSYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
WXD1_k127_5586686_2	1408444.JHYC01000001_gene1252	2.219e-39	156.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,1JCMJ@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
WXD1_k127_5586686_3	861299.J421_3353	8.212e-25	109.0	COG0319@1|root,COG0319@2|Bacteria,1ZTUP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
WXD1_k127_5586686_0	861299.J421_3354	1.047e-131	444.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	yqfF	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
WXD1_k127_5607686_0	861299.J421_5937	1.818e-317	1014.0	COG0726@1|root,COG0726@2|Bacteria,1ZUK5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_9
WXD1_k127_5607686_2	1381123.AYOD01000015_gene2481	3.708e-101	370.0	COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,2UEXR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
WXD1_k127_5607686_1	694427.Palpr_2917	5.76e-156	511.0	COG3507@1|root,COG3507@2|Bacteria,4NEMG@976|Bacteroidetes,2FPP1@200643|Bacteroidia,22WTR@171551|Porphyromonadaceae	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_43
WXD1_k127_5607686_4	717606.PaecuDRAFT_2616	3.189e-08	60.0	COG0745@1|root,COG0745@2|Bacteria,1UD16@1239|Firmicutes,4HX3U@91061|Bacilli,26ZCD@186822|Paenibacillaceae	91061|Bacilli	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WXD1_k127_5607686_3	204669.Acid345_2395	1.933e-91	320.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
WXD1_k127_5624361_1	880073.Calab_2524	2.405e-129	419.0	COG0363@1|root,COG0363@2|Bacteria,2NPPJ@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z0825	Glucosamine_iso
WXD1_k127_5624361_6	1123368.AUIS01000019_gene1213	9.244e-57	203.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales	225057|Acidithiobacillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WXD1_k127_5624361_7	1123368.AUIS01000019_gene1214	8.698e-49	188.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WXD1_k127_5624361_0	1123392.AQWL01000010_gene2304	1.275e-134	443.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KRIV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
WXD1_k127_5624361_2	1183438.GKIL_3827	1.133e-117	388.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	alx	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
WXD1_k127_5624361_3	765910.MARPU_04245	1.855e-88	302.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,1RN7G@1236|Gammaproteobacteria,1WXTT@135613|Chromatiales	135613|Chromatiales	K	PFAM HTH transcriptional regulator, LysR	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
WXD1_k127_5624361_5	1242864.D187_006237	8.639e-87	302.0	COG4850@1|root,COG4850@2|Bacteria,1R3ST@1224|Proteobacteria,437ZM@68525|delta/epsilon subdivisions,2X9TC@28221|Deltaproteobacteria,2Z0DS@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
WXD1_k127_5624361_8	1403819.BATR01000075_gene2177	3.189e-32	141.0	COG1100@1|root,COG1100@2|Bacteria,46WGX@74201|Verrucomicrobia,2IVVW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	C-terminal of Roc, COR, domain	-	-	-	-	-	-	-	-	-	-	-	-	COR,Roc,TIR_2
WXD1_k127_5624361_9	67356.KL575592_gene2858	1.075e-14	85.0	2AHAE@1|root,317KQ@2|Bacteria,2GVBK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4231
WXD1_k127_5624361_10	765420.OSCT_0544	6.666e-14	83.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi,3757S@32061|Chloroflexia	32061|Chloroflexia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
WXD1_k127_5624361_4	1267533.KB906734_gene4097	2.158e-88	308.0	COG4191@1|root,COG4191@2|Bacteria,3Y6KQ@57723|Acidobacteria,2JKAA@204432|Acidobacteriia	204432|Acidobacteriia	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
WXD1_k127_5649331_0	1128421.JAGA01000002_gene60	4.288e-186	594.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2NNKQ@2323|unclassified Bacteria	2|Bacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0030312,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0071944,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13,2.1.1.245,2.1.1.258	ko:K00197,ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00357,M00377,M00422	R00946,R02289,R09096,R09365,R10219,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_4764,iECUMN_1333.ECUMN_4545	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WXD1_k127_5649331_1	1379270.AUXF01000004_gene3330	1.746e-97	331.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
WXD1_k127_5678037_0	861299.J421_1921	2.356e-89	312.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_1921|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5678037_1	861299.J421_5909	8.283e-63	245.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5909|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5678037_2	384765.SIAM614_23792	7.365e-39	154.0	COG1994@1|root,COG1994@2|Bacteria,1QXF3@1224|Proteobacteria,2TXR8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
WXD1_k127_5678037_3	1265502.KB905936_gene2682	1.742e-36	148.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VHXV@28216|Betaproteobacteria,4ABXZ@80864|Comamonadaceae	28216|Betaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
WXD1_k127_5684099_17	1101190.ARWB01000001_gene2272	4.143e-05	54.0	29IJ4@1|root,305GB@2|Bacteria,1N0FK@1224|Proteobacteria,2UDQU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
WXD1_k127_5684099_6	1521187.JPIM01000048_gene92	1.346e-70	243.0	COG0225@1|root,COG0225@2|Bacteria,2G6JK@200795|Chloroflexi,375KD@32061|Chloroflexia	32061|Chloroflexia	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WXD1_k127_5684099_7	1111728.ATYS01000012_gene169	2.094e-68	237.0	COG2131@1|root,COG2131@2|Bacteria,1NC75@1224|Proteobacteria,1S1U2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Deoxycytidylate deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
WXD1_k127_5684099_16	1121123.AUAO01000001_gene719	1.536e-08	63.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,2KG0I@204458|Caulobacterales	204458|Caulobacterales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
WXD1_k127_5684099_9	583345.Mmol_0681	4.794e-52	188.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,2KN1B@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
WXD1_k127_5684099_10	1089455.MOPEL_009_00300	3.887e-44	169.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Cation efflux	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
WXD1_k127_5684099_5	1379270.AUXF01000002_gene1481	9.464e-77	267.0	28JIN@1|root,30U03@2|Bacteria,1ZUBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5684099_1	379066.GAU_2335	1.035e-221	705.0	COG0405@1|root,COG0405@2|Bacteria,1ZU92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WXD1_k127_5684099_4	1292034.OR37_02121	5.635e-78	271.0	COG2234@1|root,COG2234@2|Bacteria,1P2WI@1224|Proteobacteria,2U8ZH@28211|Alphaproteobacteria,2KHZR@204458|Caulobacterales	204458|Caulobacterales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WXD1_k127_5684099_14	861299.J421_2404	5.968e-17	94.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5684099_8	234267.Acid_4382	2.199e-63	234.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
WXD1_k127_5684099_0	381666.H16_B1700	0.0	1261.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,1K6SR@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA1	-	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WXD1_k127_5684099_2	381666.H16_B1701	4.784e-217	687.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,1K5P1@119060|Burkholderiaceae	28216|Betaproteobacteria	C	formate dehydrogenase	fdwB	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
WXD1_k127_5684099_12	861299.J421_6160	3.013e-22	111.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_6160|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WXD1_k127_5684099_13	861299.J421_1682	6.492e-22	108.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
WXD1_k127_5684099_11	580340.Tlie_1369	2.967e-24	121.0	COG4942@1|root,COG4942@2|Bacteria,3T9S7@508458|Synergistetes	508458|Synergistetes	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
WXD1_k127_5684099_3	290397.Adeh_2532	2.459e-142	469.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2YWFY@29|Myxococcales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
WXD1_k127_5704308_1	326427.Cagg_2090	1.767e-220	705.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,377XJ@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
WXD1_k127_5704308_2	264732.Moth_1850	1.342e-162	535.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,42FUX@68295|Thermoanaerobacterales	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
WXD1_k127_5704308_0	592015.HMPREF1705_00168	2.407e-291	907.0	COG0296@1|root,COG0296@2|Bacteria,3TA51@508458|Synergistetes	508458|Synergistetes	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
WXD1_k127_5704308_3	264732.Moth_1809	2.34e-150	484.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,42FTG@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
WXD1_k127_5725488_0	1183438.GKIL_0436	6.896e-108	367.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WXD1_k127_5725488_6	378806.STAUR_5295	7.013e-07	59.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria,2Z1BM@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WXD1_k127_5725488_3	1396141.BATP01000039_gene1303	7.326e-75	259.0	COG0327@1|root,COG0327@2|Bacteria,46U7Z@74201|Verrucomicrobia,2IU4W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
WXD1_k127_5725488_5	1121904.ARBP01000019_gene2766	1.589e-13	76.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,47SCM@768503|Cytophagia	976|Bacteroidetes	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WXD1_k127_5725488_4	697303.Thewi_0928	2.041e-29	127.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,24JM4@186801|Clostridia,42FFZ@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WXD1_k127_5725488_2	861299.J421_1167	1.124e-76	271.0	COG1475@1|root,COG1475@2|Bacteria,1ZSKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WXD1_k127_5725488_1	861299.J421_1165	6.322e-99	331.0	COG1192@1|root,COG1192@2|Bacteria,1ZTH2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WXD1_k127_5732939_0	383372.Rcas_0812	3.182e-184	588.0	COG1449@1|root,COG1449@2|Bacteria,2G5XB@200795|Chloroflexi,3768X@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
WXD1_k127_5732939_1	1121468.AUBR01000021_gene2826	1.001e-34	139.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,42FTG@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18,3.2.1.141	ko:K00700,ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110,R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3459
WXD1_k127_5737016_2	1089550.ATTH01000001_gene604	1.692e-10	66.0	COG0003@1|root,COG0003@2|Bacteria,4NKJ7@976|Bacteroidetes	976|Bacteroidetes	D	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
WXD1_k127_5737016_1	246197.MXAN_6410	4.584e-108	368.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,42YPE@68525|delta/epsilon subdivisions,2WU63@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
WXD1_k127_5737016_0	861299.J421_0892	7.473e-146	480.0	COG0076@1|root,COG0076@2|Bacteria,1ZTFP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
WXD1_k127_5737016_3	1267533.KB906733_gene3071	2.14e-09	66.0	COG2823@1|root,COG2823@2|Bacteria,3Y99E@57723|Acidobacteria	57723|Acidobacteria	S	Periplasmic or secreted lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_575008_6	469383.Cwoe_5289	1.386e-19	92.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4CQ0I@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	-	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WXD1_k127_575008_4	1379270.AUXF01000004_gene3176	1.679e-41	163.0	COG1051@1|root,COG1051@2|Bacteria,1ZTP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WXD1_k127_575008_3	1446473.JHWH01000013_gene2462	7.264e-42	170.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,2PUP2@265|Paracoccus	28211|Alphaproteobacteria	S	AI-2E family transporter	perM	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
WXD1_k127_575008_8	115713.CPn_0615	1.419e-08	66.0	COG0558@1|root,COG0558@2|Bacteria,2JG6R@204428|Chlamydiae	204428|Chlamydiae	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA_1	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WXD1_k127_575008_1	1111479.AXAR01000003_gene1676	9.906e-104	347.0	COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli,279CW@186823|Alicyclobacillaceae	91061|Bacilli	C	Ferredoxin--NADP reductase	trxB5	-	1.18.1.2,1.19.1.1	ko:K21567	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
WXD1_k127_575008_2	861299.J421_2716	1.217e-48	178.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2716|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_575008_5	379066.GAU_2497	2.145e-21	104.0	2C0MY@1|root,30KW5@2|Bacteria,1ZTVN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_575008_0	379066.GAU_1987	7.406e-150	484.0	COG0492@1|root,COG0492@2|Bacteria,1ZTEH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WXD1_k127_575008_7	269799.Gmet_1671	1.204e-09	62.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2WUGK@28221|Deltaproteobacteria,43U2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_1671	Transgly,Transpeptidase
WXD1_k127_5761244_2	926550.CLDAP_39250	6.089e-24	109.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WXD1_k127_5761244_3	1151117.AJLF01000001_gene954	7.516e-11	71.0	COG2306@1|root,arCOG05760@2157|Archaea,2XX0W@28890|Euryarchaeota,243ZF@183968|Thermococci	183968|Thermococci	S	Protein of unknown function (DUF402)	-	-	-	ko:K09145	-	-	-	-	ko00000	-	-	-	DUF402
WXD1_k127_5761244_0	1232410.KI421415_gene3026	2.138e-167	550.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2X28Y@28221|Deltaproteobacteria,43U5A@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N,ECH_1
WXD1_k127_5761244_1	1307759.JOMJ01000003_gene678	1.725e-29	120.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2M8GP@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WXD1_k127_5769159_1	477641.MODMU_0270	1.175e-78	273.0	COG0789@1|root,COG0789@2|Bacteria,2H5GI@201174|Actinobacteria,4ES30@85013|Frankiales	201174|Actinobacteria	K	Transcription regulator MerR, DNA binding	tipA	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1,TipAS
WXD1_k127_5769159_2	1379698.RBG1_1C00001G0288	2.584e-34	134.0	COG0234@1|root,COG0234@2|Bacteria,2NPW2@2323|unclassified Bacteria	2|Bacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WXD1_k127_5769159_0	1379270.AUXF01000005_gene790	6.467e-136	435.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WXD1_k127_5786470_8	861299.J421_3866	1.134e-77	285.0	2EWAK@1|root,33PPB@2|Bacteria,1ZT00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5786470_4	1379270.AUXF01000004_gene3283	6.142e-119	389.0	COG0568@1|root,COG0568@2|Bacteria,1ZSNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WXD1_k127_5786470_12	1379270.AUXF01000002_gene1786	7.766e-39	162.0	COG0599@1|root,COG0599@2|Bacteria,1ZTRJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WXD1_k127_5786470_14	1121920.AUAU01000027_gene1497	5.139e-20	102.0	28JRZ@1|root,2Z9HI@2|Bacteria,3Y7HD@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
WXD1_k127_5786470_1	861299.J421_4185	1.874e-156	512.0	COG0304@1|root,COG0304@2|Bacteria,1ZTE1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WXD1_k127_5786470_10	861299.J421_4184	3.532e-48	184.0	COG2867@1|root,COG2867@2|Bacteria,1ZTVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
WXD1_k127_5786470_9	861299.J421_4181	1.971e-50	198.0	COG0644@1|root,COG0644@2|Bacteria,1ZTEM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glucose inhibited division protein A	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
WXD1_k127_5786470_5	383372.Rcas_3448	2.287e-109	365.0	COG0123@1|root,COG0123@2|Bacteria,2G89I@200795|Chloroflexi,376ST@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WXD1_k127_5786470_13	324057.Pjdr2_2585	2.343e-36	154.0	COG0500@1|root,COG2226@2|Bacteria,1V1WV@1239|Firmicutes,4HFQ9@91061|Bacilli,26SKG@186822|Paenibacillaceae	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WXD1_k127_5786470_6	1379270.AUXF01000004_gene3236	5.794e-109	368.0	COG0402@1|root,COG0402@2|Bacteria,1ZSMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WXD1_k127_5786470_11	379066.GAU_0755	8.189e-42	175.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	ko:K07001,ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,CarbopepD_reg_2,DUF11,Peptidase_S74,Plug
WXD1_k127_5786470_7	1125863.JAFN01000001_gene2253	7.32e-103	350.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_5786470_2	1128421.JAGA01000002_gene1707	1.611e-142	469.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	aprE	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8
WXD1_k127_5786470_0	379066.GAU_2166	1.332e-227	717.0	COG1866@1|root,COG1866@2|Bacteria,1ZSTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WXD1_k127_5786470_3	861299.J421_3775	8.818e-126	416.0	COG1078@1|root,COG1078@2|Bacteria,1ZT3F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
WXD1_k127_579307_4	1379270.AUXF01000002_gene1832	8.318e-75	265.0	COG4299@1|root,COG4299@2|Bacteria,1ZT4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
WXD1_k127_579307_1	1121920.AUAU01000023_gene2395	3.162e-223	719.0	COG0065@1|root,COG0066@1|root,COG0065@2|Bacteria,COG0066@2|Bacteria	2|Bacteria	E	3-isopropylmalate dehydratase activity	leuD	-	4.2.1.3,4.2.1.33,4.2.1.35	ko:K01681,ko:K01703,ko:K01704,ko:K17749	ko00020,ko00290,ko00400,ko00630,ko00660,ko00720,ko00966,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00290,map00400,map00630,map00660,map00720,map00966,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00432,M00535,M00740	R01324,R01325,R01900,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170,R10501	RC00497,RC00498,RC00618,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WXD1_k127_579307_3	1123290.AUDQ01000016_gene843	3.883e-100	339.0	COG0624@1|root,COG0624@2|Bacteria,1TPMJ@1239|Firmicutes,4HB39@91061|Bacilli,26ESA@186818|Planococcaceae	91061|Bacilli	E	Peptidase dimerisation domain	dapE_3	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WXD1_k127_579307_0	861299.J421_1758	1.221e-244	769.0	COG0591@1|root,COG0591@2|Bacteria,1ZT93@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WXD1_k127_579307_2	497964.CfE428DRAFT_5756	1.318e-107	359.0	COG1801@1|root,COG1801@2|Bacteria,46TPE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WXD1_k127_579307_6	861299.J421_4447	5.607e-16	89.0	COG4783@1|root,COG4783@2|Bacteria,1ZU5G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_579307_5	278957.ABEA03000010_gene3916	1.956e-37	147.0	COG0614@1|root,COG0614@2|Bacteria,46XU2@74201|Verrucomicrobia,3K9Q9@414999|Opitutae	414999|Opitutae	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
WXD1_k127_5809417_3	1379270.AUXF01000006_gene256	3.121e-109	358.0	COG1060@1|root,COG1060@2|Bacteria,1ZSRJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
WXD1_k127_5809417_1	861299.J421_3265	1.237e-119	408.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
WXD1_k127_5809417_9	1380390.JIAT01000009_gene1491	9.183e-43	160.0	COG0041@1|root,COG0041@2|Bacteria,2IFFD@201174|Actinobacteria,4CQ7C@84995|Rubrobacteria	84995|Rubrobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WXD1_k127_5809417_8	1382356.JQMP01000004_gene629	6.641e-51	187.0	COG0245@1|root,COG0245@2|Bacteria,2G6RA@200795|Chloroflexi,27YBC@189775|Thermomicrobia	189775|Thermomicrobia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
WXD1_k127_5809417_12	861299.J421_3263	3.436e-31	134.0	COG0586@1|root,COG0586@2|Bacteria,1ZTVI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WXD1_k127_5809417_4	861299.J421_3262	9.593e-109	362.0	COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WXD1_k127_5809417_6	935863.AWZR01000001_gene2081	5.222e-78	265.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1X41Q@135614|Xanthomonadales	135614|Xanthomonadales	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WXD1_k127_5809417_7	379066.GAU_1625	5.259e-67	237.0	COG1212@1|root,COG1212@2|Bacteria,1ZSRD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
WXD1_k127_5809417_0	861299.J421_3257	6.538e-255	796.0	COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WXD1_k127_5809417_5	379066.GAU_1623	5.724e-91	322.0	COG2877@1|root,COG2877@2|Bacteria,1ZUCD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
WXD1_k127_5809417_10	379066.GAU_1622	1.494e-37	154.0	COG1778@1|root,COG1778@2|Bacteria,1ZTTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
WXD1_k127_5809417_2	379066.GAU_1621	3.28e-114	376.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1ZT08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
WXD1_k127_5812411_1	204669.Acid345_2967	2.191e-75	259.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950,ko:K09163	-	-	-	-	ko00000	-	-	-	HD
WXD1_k127_5812411_0	204669.Acid345_2966	9.79e-163	519.0	COG2079@1|root,COG2079@2|Bacteria,3Y5N1@57723|Acidobacteria,2JK64@204432|Acidobacteriia	204432|Acidobacteriia	S	MmgE/PrpD family	-	-	4.2.1.79	ko:K01720	ko00640,map00640	-	R04424	RC01152	ko00000,ko00001,ko01000	-	-	-	MmgE_PrpD
WXD1_k127_5827879_1	1379270.AUXF01000001_gene2588	2.301e-104	370.0	COG4188@1|root,COG4188@2|Bacteria,1ZUJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
WXD1_k127_5827879_2	485913.Krac_4695	4.408e-63	235.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	2.1.1.179	ko:K18845	-	-	-	-	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	APH
WXD1_k127_5827879_3	326427.Cagg_2802	1.363e-53	215.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5827879_0	1123276.KB893279_gene2119	5.652e-108	361.0	COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,47MF6@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_5846762_5	926549.KI421517_gene456	3.122e-86	292.0	arCOG09511@1|root,2Z9DH@2|Bacteria,4NIMU@976|Bacteroidetes,47N8K@768503|Cytophagia	976|Bacteroidetes	S	FRG	-	-	-	-	-	-	-	-	-	-	-	-	FRG
WXD1_k127_5846762_2	316067.Geob_1385	9.043e-144	487.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42NDS@68525|delta/epsilon subdivisions,2WJDE@28221|Deltaproteobacteria,43V4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
WXD1_k127_5846762_6	768671.ThimaDRAFT_1696	5.666e-64	226.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1WYDE@135613|Chromatiales	135613|Chromatiales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
WXD1_k127_5846762_3	1123401.JHYQ01000009_gene2293	3.375e-131	430.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria,4609Z@72273|Thiotrichales	72273|Thiotrichales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
WXD1_k127_5846762_4	1379270.AUXF01000001_gene2605	2.378e-125	412.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5846762_1	1191523.MROS_0402	7.088e-214	677.0	COG2978@1|root,COG2978@2|Bacteria	2|Bacteria	H	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity	ydaH	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
WXD1_k127_5846762_0	379066.GAU_3117	0.0	1114.0	COG4447@1|root,COG4447@2|Bacteria,1ZSRH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WXD1_k127_5846762_7	1379270.AUXF01000003_gene3588	1.168e-22	113.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	TerB
WXD1_k127_5850990_2	861299.J421_0415	2.248e-102	358.0	COG0840@1|root,COG0840@2|Bacteria,1ZUEF@142182|Gemmatimonadetes	2|Bacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,DUF3365,HAMP,MCPsignal,dCache_1
WXD1_k127_5850990_3	1163407.UU7_15155	2.157e-52	205.0	COG3203@1|root,COG3203@2|Bacteria,1QSVK@1224|Proteobacteria,1RWG6@1236|Gammaproteobacteria,1X3R0@135614|Xanthomonadales	135614|Xanthomonadales	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5850990_1	251221.35210640	1.265e-156	554.0	COG0383@1|root,COG0383@2|Bacteria,1G1RB@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM Glycosyl hydrolases family 38 C-terminal domain	ams1	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WXD1_k127_5850990_0	518766.Rmar_0638	1.408e-260	819.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1FIMH@1100069|Bacteroidetes Order II. Incertae sedis	2|Bacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WXD1_k127_5850990_4	518766.Rmar_0637	1.776e-15	91.0	2FDJV@1|root,345M5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_586681_6	379066.GAU_1405	1.971e-19	88.0	COG2204@1|root,COG2204@2|Bacteria,1ZTMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WXD1_k127_586681_1	401526.TcarDRAFT_2115	1.338e-107	371.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,4H3AN@909932|Negativicutes	909932|Negativicutes	NT	Chemotaxis protein CheA	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
WXD1_k127_586681_4	379066.GAU_1407	1.333e-50	186.0	COG1776@1|root,COG1776@2|Bacteria,1ZTIW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	CheC-like family	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
WXD1_k127_586681_2	1379270.AUXF01000005_gene670	2.631e-90	332.0	COG0457@1|root,COG0457@2|Bacteria,1ZSS6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WXD1_k127_586681_5	316274.Haur_0845	1.718e-35	149.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,374ST@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
WXD1_k127_586681_7	1144275.COCOR_02249	2.863e-08	65.0	COG0457@1|root,COG3063@1|root,COG4783@1|root,COG0457@2|Bacteria,COG3063@2|Bacteria,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,DUF560,TPR_16,TPR_19,TPR_2,TPR_8
WXD1_k127_586681_9	243232.MJ_1340	1.47e-05	54.0	COG2018@1|root,arCOG02603@2157|Archaea,2XY6Z@28890|Euryarchaeota,23R2D@183939|Methanococci	183939|Methanococci	S	PFAM Roadblock LC7 family protein	-	GO:0001101,GO:0003674,GO:0005085,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0019899,GO:0023051,GO:0023056,GO:0032006,GO:0032008,GO:0032947,GO:0042221,GO:0043200,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051020,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0098772,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
WXD1_k127_586681_8	404380.Gbem_3963	2.397e-06	56.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
WXD1_k127_586681_3	1379698.RBG1_1C00001G1745	2.253e-74	255.0	COG1100@1|root,COG1100@2|Bacteria,2NPDD@2323|unclassified Bacteria	2|Bacteria	K	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,DUF697,MMR_HSR1
WXD1_k127_586681_0	379066.GAU_1411	2.536e-111	381.0	COG0593@1|root,COG0593@2|Bacteria,1ZUFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bacterial dnaA  protein	-	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA
WXD1_k127_5921178_2	7460.GB41094-PA	6.306e-20	106.0	COG0457@1|root,KOG1124@2759|Eukaryota,38F8U@33154|Opisthokonta,3BAQE@33208|Metazoa,3CV5D@33213|Bilateria,41XV8@6656|Arthropoda,3SIVI@50557|Insecta,46JRX@7399|Hymenoptera	33208|Metazoa	S	Tetratricopeptide repeat	TMTC1	-	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
WXD1_k127_5921178_0	1210884.HG799467_gene13174	3.187e-40	168.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WXD1_k127_5921178_3	1382306.JNIM01000001_gene3762	2.53e-09	70.0	COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WXD1_k127_5921178_1	118173.KB235914_gene3902	1.644e-33	132.0	COG1215@1|root,COG1215@2|Bacteria,1G5YB@1117|Cyanobacteria,1HB60@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WXD1_k127_5921332_7	861299.J421_3401	1.028e-125	409.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WXD1_k127_5921332_6	861299.J421_3400	1.792e-133	438.0	COG0612@1|root,COG0612@2|Bacteria,1ZSPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_5921332_3	861299.J421_3399	3.273e-171	544.0	COG0686@1|root,COG0686@2|Bacteria,1ZSSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WXD1_k127_5921332_15	1161401.ASJA01000002_gene2557	3.29e-43	169.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,43XND@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WXD1_k127_5921332_4	861299.J421_3398	5.591e-170	539.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WXD1_k127_5921332_18	1379270.AUXF01000006_gene134	1.328e-37	154.0	COG1792@1|root,COG1792@2|Bacteria,1ZSYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WXD1_k127_5921332_21	861299.J421_3396	1.89e-10	70.0	2CIX2@1|root,33ZZP@2|Bacteria,1ZTZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
WXD1_k127_5921332_9	379066.GAU_1757	2.52e-119	396.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WXD1_k127_5921332_10	880073.Calab_0770	4.962e-91	331.0	COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria	2|Bacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD,iPC815.YPO2768,iUTI89_1310.UTI89_C2601	Carboxyl_trans
WXD1_k127_5921332_12	379066.GAU_1755	2.353e-84	295.0	COG0285@1|root,COG0285@2|Bacteria,1ZSRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
WXD1_k127_5921332_5	861299.J421_3391	5.326e-138	451.0	COG0124@1|root,COG0124@2|Bacteria,1ZSXX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
WXD1_k127_5921332_1	861299.J421_3390	1.23e-201	638.0	COG0442@1|root,COG0442@2|Bacteria,1ZT48@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
WXD1_k127_5921332_8	690850.Desaf_3042	1.616e-124	413.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2M9PA@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WXD1_k127_5921332_2	1122137.AQXF01000002_gene299	8e-197	626.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
WXD1_k127_5921332_0	379066.GAU_1492	0.0	1167.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WXD1_k127_5921332_22	861299.J421_2972	6.74e-08	61.0	28ZEQ@1|root,2ZM6A@2|Bacteria,1ZU2C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5921332_19	504728.K649_10790	7.62e-35	140.0	COG0346@1|root,COG0346@2|Bacteria,1WJZW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
WXD1_k127_5921332_17	1379270.AUXF01000005_gene563	5.865e-41	154.0	COG3118@1|root,COG3118@2|Bacteria,1ZTS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WXD1_k127_5921332_14	861299.J421_2975	4.085e-79	274.0	COG0313@1|root,COG0313@2|Bacteria,1ZTK1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WXD1_k127_5921332_11	861299.J421_2976	8.603e-89	311.0	COG1657@1|root,COG1657@2|Bacteria,1ZSPV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
WXD1_k127_5921332_13	861299.J421_2977	6.386e-83	313.0	COG1196@1|root,COG4942@1|root,COG1196@2|Bacteria,COG4942@2|Bacteria,1ZSU8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5921332_20	861299.J421_2978	1.244e-19	105.0	COG1729@1|root,COG1729@2|Bacteria,1ZTBJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	-
WXD1_k127_5921332_16	1406840.Q763_15535	3.745e-43	161.0	2CD20@1|root,2Z7SQ@2|Bacteria,4NEQ1@976|Bacteroidetes,1HXI3@117743|Flavobacteriia,2NUKY@237|Flavobacterium	976|Bacteroidetes	S	Asparagine synthetase B	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5922028_3	401526.TcarDRAFT_2399	1.272e-57	204.0	COG1643@1|root,COG1643@2|Bacteria,1TPET@1239|Firmicutes,4H3XG@909932|Negativicutes	909932|Negativicutes	L	ATP-dependent helicase HrpB	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
WXD1_k127_5922028_4	309807.SRU_2540	3.013e-38	156.0	COG1566@1|root,COG1566@2|Bacteria,4NH7M@976|Bacteroidetes	976|Bacteroidetes	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
WXD1_k127_5922028_2	861299.J421_6319	2.911e-72	255.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Condensation,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,PP-binding,TPR_1,TPR_16,TPR_8
WXD1_k127_5922028_0	357808.RoseRS_2711	1.344e-190	610.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,2G64U@200795|Chloroflexi,374ZG@32061|Chloroflexia	32061|Chloroflexia	P	YidE YbjL duplication domain protein	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
WXD1_k127_5922028_1	1206726.BAFV01000071_gene4938	1.046e-135	446.0	COG0520@1|root,COG0520@2|Bacteria,2IAKT@201174|Actinobacteria,4FZJ6@85025|Nocardiaceae	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_5928376_4	1121949.AQXT01000002_gene2823	5.269e-09	64.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,43X5V@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
WXD1_k127_5928376_2	143224.JQMD01000002_gene3284	3.647e-60	225.0	COG0657@1|root,COG0657@2|Bacteria,4NGAF@976|Bacteroidetes,1HZ5F@117743|Flavobacteriia	976|Bacteroidetes	I	Protein of unknown function (DUF1460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460
WXD1_k127_5928376_5	861299.J421_2391	5.063e-07	61.0	28TV6@1|root,2ZG24@2|Bacteria,1ZV98@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5928376_1	1380394.JADL01000001_gene3101	5.68e-70	253.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,2JV5D@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Sugar (and other) transporter	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1
WXD1_k127_5928376_6	1178482.BJB45_09640	0.0006584	46.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,1S8YP@1236|Gammaproteobacteria,1XMJZ@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WXD1_k127_5928376_3	861299.J421_5740	9.963e-57	216.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5740|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5928376_0	518766.Rmar_0596	2.597e-163	526.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
WXD1_k127_5943915_1	326427.Cagg_0503	1.667e-40	158.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,375RW@32061|Chloroflexia	32061|Chloroflexia	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WXD1_k127_5943915_0	1173028.ANKO01000116_gene5724	7.761e-76	266.0	COG0546@1|root,COG0546@2|Bacteria,1G6AW@1117|Cyanobacteria,1HCZI@1150|Oscillatoriales	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WXD1_k127_5943915_2	745014.OMB55_00017470	4.363e-13	73.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,1RYSW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EQ	L-aminopeptidase D-esterase	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WXD1_k127_5944282_5	1120936.KB907210_gene5715	9.356e-09	63.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria,4EHNS@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WXD1_k127_5944282_1	502025.Hoch_6586	9.322e-69	261.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,42NIZ@68525|delta/epsilon subdivisions,2WM5U@28221|Deltaproteobacteria,2Z315@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
WXD1_k127_5944282_4	861299.J421_3920	1.024e-15	82.0	2F9BP@1|root,341NP@2|Bacteria,1ZTX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5944282_2	379066.GAU_2452	1.135e-19	94.0	COG3339@1|root,COG3339@2|Bacteria,1ZTZ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
WXD1_k127_5944282_0	861299.J421_3918	4.908e-214	686.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WXD1_k127_5944282_3	1382356.JQMP01000003_gene2378	2.996e-17	94.0	COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi,27XGI@189775|Thermomicrobia	189775|Thermomicrobia	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_2
WXD1_k127_5963306_0	861299.J421_3104	2.246e-62	237.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1ZSMY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,Lactamase_B
WXD1_k127_5982802_3	1379270.AUXF01000001_gene1873	5.436e-126	410.0	COG3525@1|root,COG3525@2|Bacteria,1ZUG8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
WXD1_k127_5982802_1	32057.KB217478_gene3617	1.564e-183	600.0	COG0467@1|root,COG0467@2|Bacteria,1G2XC@1117|Cyanobacteria,1HTZ7@1161|Nostocales	1117|Cyanobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
WXD1_k127_5982802_4	1144275.COCOR_06733	1.556e-62	230.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1MXH7@1224|Proteobacteria,43AYG@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WXD1_k127_5982802_2	1210884.HG799462_gene9086	4.887e-147	506.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_5982802_0	298655.KI912266_gene2945	5.416e-253	790.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4ES6Q@85013|Frankiales	201174|Actinobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
WXD1_k127_5998425_2	234267.Acid_5076	4.257e-121	392.0	COG3285@1|root,COG3285@2|Bacteria,3Y74I@57723|Acidobacteria	57723|Acidobacteria	L	dna ligase	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
WXD1_k127_5998425_1	452637.Oter_4139	1.506e-123	405.0	COG1793@1|root,COG1793@2|Bacteria,46TP1@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM ATP dependent DNA ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
WXD1_k127_5998425_3	1121937.AUHJ01000009_gene1566	1.448e-56	206.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,468KZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WXD1_k127_5998425_4	402777.KB235904_gene4553	4.753e-39	155.0	COG3861@1|root,COG3861@2|Bacteria,1G5I2@1117|Cyanobacteria,1HARY@1150|Oscillatoriales	1117|Cyanobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5998425_0	861299.J421_1618	2.229e-128	428.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_5999310_7	861299.J421_1944	4.747e-54	195.0	COG0659@1|root,COG0659@2|Bacteria,1ZTYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
WXD1_k127_5999310_2	448385.sce7314	1.068e-82	281.0	COG3382@1|root,COG3382@2|Bacteria,1N6A7@1224|Proteobacteria,4337M@68525|delta/epsilon subdivisions,2WXR0@28221|Deltaproteobacteria,2YUZ2@29|Myxococcales	28221|Deltaproteobacteria	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
WXD1_k127_5999310_3	251229.Chro_5142	1.006e-78	274.0	2DBB1@1|root,2Z854@2|Bacteria,1G05N@1117|Cyanobacteria,3VHVS@52604|Pleurocapsales	1117|Cyanobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
WXD1_k127_5999310_4	450851.PHZ_c3138	7.229e-66	231.0	COG0740@1|root,COG0740@2|Bacteria,1RBNX@1224|Proteobacteria,2U5ZH@28211|Alphaproteobacteria,2KIMN@204458|Caulobacterales	204458|Caulobacterales	OU	Clp protease	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WXD1_k127_5999310_1	861299.J421_1019	2.54e-106	350.0	COG1402@1|root,COG1402@2|Bacteria,1ZTKC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WXD1_k127_5999310_6	861299.J421_4117	9.064e-63	219.0	COG2318@1|root,COG2318@2|Bacteria,1ZV1M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
WXD1_k127_5999310_9	1379698.RBG1_1C00001G0743	1.861e-44	169.0	COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria	2|Bacteria	S	DinB superfamily	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
WXD1_k127_5999310_12	1144275.COCOR_03245	8.846e-23	109.0	2935G@1|root,2ZQNI@2|Bacteria,1Q1RV@1224|Proteobacteria,437F3@68525|delta/epsilon subdivisions,2X2MJ@28221|Deltaproteobacteria,2YTTE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_5999310_10	1218084.BBJK01000002_gene104	6.661e-40	162.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1MWTF@1224|Proteobacteria,2VW1Z@28216|Betaproteobacteria,1K500@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix-turn-helix- domain containing protein, AraC type	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
WXD1_k127_5999310_0	243231.GSU1576	1.238e-112	368.0	COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,42Z74@68525|delta/epsilon subdivisions,2WTUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WXD1_k127_5999310_8	76114.ebD26	3.154e-50	185.0	COG2020@1|root,COG2020@2|Bacteria,1QVIW@1224|Proteobacteria,2VX8F@28216|Betaproteobacteria	28216|Betaproteobacteria	O	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WXD1_k127_5999310_5	1122621.ATZA01000009_gene249	1.045e-65	233.0	COG1073@1|root,COG1073@2|Bacteria,4PN7H@976|Bacteroidetes,1J0MK@117747|Sphingobacteriia	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WXD1_k127_5999310_13	765911.Thivi_1021	1.467e-11	69.0	COG1409@1|root,COG1409@2|Bacteria,1MV0H@1224|Proteobacteria,1S1ZM@1236|Gammaproteobacteria,1WY1M@135613|Chromatiales	135613|Chromatiales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6014867_9	379066.GAU_0445	4.22e-35	151.0	COG0840@1|root,COG2770@1|root,COG0840@2|Bacteria,COG2770@2|Bacteria,1ZUEF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
WXD1_k127_6014867_15	1246995.AFR_08760	0.0005587	52.0	COG0840@1|root,COG0840@2|Bacteria,2ID12@201174|Actinobacteria	201174|Actinobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal
WXD1_k127_6014867_7	497964.CfE428DRAFT_2237	1.848e-45	177.0	COG0109@1|root,COG0109@2|Bacteria,46SQE@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
WXD1_k127_6014867_12	1382306.JNIM01000001_gene4040	4.697e-12	79.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WXD1_k127_6014867_0	608538.HTH_0153	2.05e-197	631.0	COG0843@1|root,COG0843@2|Bacteria	2|Bacteria	C	heme-copper terminal oxidase activity	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WXD1_k127_6014867_6	1244869.H261_01552	2.278e-57	211.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2UJSY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	cytochrome c oxidase (Subunit II)	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6014867_13	1244869.H261_01557	1.983e-05	49.0	2ERCE@1|root,33IY3@2|Bacteria,1NNN9@1224|Proteobacteria,2UXY5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6014867_3	1123360.thalar_02888	7.914e-72	265.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2UQID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,FlpD
WXD1_k127_6014867_16	1437824.BN940_02361	0.0005671	49.0	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6014867_2	522306.CAP2UW1_1793	3.076e-89	306.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria	1224|Proteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WXD1_k127_6014867_8	1121456.ATVA01000018_gene271	2.328e-39	168.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WIJ8@28221|Deltaproteobacteria,2M82Q@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
WXD1_k127_6014867_5	401053.AciPR4_1688	1.049e-65	246.0	COG1691@1|root,COG1691@2|Bacteria,3Y3BX@57723|Acidobacteria,2JI0G@204432|Acidobacteriia	204432|Acidobacteriia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
WXD1_k127_6014867_1	379066.GAU_1740	1.475e-132	430.0	COG0042@1|root,COG0042@2|Bacteria,1ZSQC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
WXD1_k127_6014867_4	861299.J421_3386	3.382e-68	234.0	COG1762@1|root,COG1762@2|Bacteria,1ZTIY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
WXD1_k127_6014867_14	1047013.AQSP01000122_gene2258	2.959e-05	55.0	COG1762@1|root,COG1762@2|Bacteria,2NPVC@2323|unclassified Bacteria	2|Bacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.202,2.7.13.3	ko:K02768,ko:K02769,ko:K02770,ko:K02806,ko:K07646	ko00051,ko01100,ko01120,ko02020,ko02060,map00051,map01100,map01120,map02020,map02060	M00273,M00454	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022	4.A.2.1	-	-	KdpD,Na_H_Exchanger,PTS_EIIA_2
WXD1_k127_6014867_10	861299.J421_3136	8.286e-20	94.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	DctA-YdbH
WXD1_k127_6014867_11	290397.Adeh_0419	5.708e-19	96.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2YU0Y@29|Myxococcales	28221|Deltaproteobacteria	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
WXD1_k127_6034725_0	861299.J421_0071	3.078e-207	662.0	COG0745@1|root,COG0784@1|root,COG0840@1|root,COG1511@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG1511@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	MA20_07280	-	2.7.13.3	ko:K03407,ko:K12257	ko02020,ko02024,ko02030,ko03060,ko03070,map02020,map02024,map02030,map03060,map03070	M00335,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	2.A.6.4	-	-	4HB_MCP_1,CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
WXD1_k127_6034725_1	861299.J421_4503	1.27e-145	482.0	COG5002@1|root,COG5002@2|Bacteria,1ZVAT@142182|Gemmatimonadetes	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WXD1_k127_6034725_2	649831.L083_2388	3.271e-19	95.0	COG0745@1|root,COG0745@2|Bacteria,2GSB5@201174|Actinobacteria,4DJJ0@85008|Micromonosporales	201174|Actinobacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WXD1_k127_604188_5	446468.Ndas_5185	3.795e-22	101.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4EGUK@85012|Streptosporangiales	201174|Actinobacteria	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
WXD1_k127_604188_7	1122185.N792_08320	1.047e-06	61.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RQCR@1236|Gammaproteobacteria,1X4SZ@135614|Xanthomonadales	135614|Xanthomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Reg_prop,Y_Y_Y
WXD1_k127_604188_2	861299.J421_3009	1.253e-57	215.0	COG0611@1|root,COG0611@2|Bacteria,1ZTIU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WXD1_k127_604188_4	880072.Desac_0811	1.529e-40	165.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2MRQY@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WXD1_k127_604188_0	518766.Rmar_1688	2.051e-184	587.0	COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,1FJ5T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WXD1_k127_604188_8	572477.Alvin_0392	0.0006616	52.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1WZ9J@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
WXD1_k127_604188_1	448385.sce4900	6.7e-133	433.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2YU5V@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WXD1_k127_604188_3	861299.J421_1989	1.181e-51	187.0	COG2940@1|root,COG2940@2|Bacteria,1ZTHI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cysteine-rich motif following a subset of SET domains	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
WXD1_k127_604188_6	378806.STAUR_3666	3.989e-22	108.0	COG5653@1|root,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria,42VU5@68525|delta/epsilon subdivisions,2WSGU@28221|Deltaproteobacteria,2YXKC@29|Myxococcales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WXD1_k127_6078052_7	1089546.AQUI01000002_gene2642	7.405e-07	59.0	COG1846@1|root,COG1846@2|Bacteria,2HGPX@201174|Actinobacteria,40A72@622450|Actinopolysporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
WXD1_k127_6078052_1	1192034.CAP_8765	1.415e-143	470.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2WM3N@28221|Deltaproteobacteria,2YUFY@29|Myxococcales	28221|Deltaproteobacteria	K	AlkA N-terminal domain	ada	-	3.2.2.21	ko:K13529,ko:K13530	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
WXD1_k127_6078052_6	626887.J057_16580	3.724e-43	179.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,467W5@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
WXD1_k127_6078052_2	379066.GAU_0214	7.203e-110	379.0	COG0308@1|root,COG0308@2|Bacteria,1ZU50@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WXD1_k127_6078052_0	1232410.KI421412_gene169	8.209e-200	647.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42NQ1@68525|delta/epsilon subdivisions,2X5KW@28221|Deltaproteobacteria,43SYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WXD1_k127_6078052_3	861299.J421_5988	1.624e-90	306.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
WXD1_k127_6078052_4	404589.Anae109_0937	7.66e-72	254.0	COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
WXD1_k127_6078052_5	338963.Pcar_1870	3.328e-66	246.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,43S4Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
WXD1_k127_6111376_0	861299.J421_3070	1.001e-123	417.0	COG0768@1|root,COG0768@2|Bacteria,1ZSYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
WXD1_k127_6112816_0	861299.J421_3809	1.014e-198	634.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
WXD1_k127_6112816_1	429009.Adeg_1891	2.738e-138	452.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42FXP@68295|Thermoanaerobacterales	186801|Clostridia	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WXD1_k127_6118382_1	326427.Cagg_2090	2.275e-254	813.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,377XJ@32061|Chloroflexia	32061|Chloroflexia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
WXD1_k127_6118382_0	1173027.Mic7113_3737	1.835e-254	803.0	COG0296@1|root,COG0366@1|root,COG0296@2|Bacteria,COG0366@2|Bacteria,1G2ZI@1117|Cyanobacteria,1H9FE@1150|Oscillatoriales	1117|Cyanobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
WXD1_k127_6118382_4	40571.JOEA01000041_gene4655	3.605e-05	54.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria,4EDJP@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
WXD1_k127_6118382_2	1254432.SCE1572_33570	1.689e-109	366.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2YUI5@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
WXD1_k127_6118382_3	1254432.SCE1572_13235	5.465e-25	113.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
WXD1_k127_6121868_6	861299.J421_0382	3.345e-155	501.0	COG1940@1|root,COG1940@2|Bacteria,1ZV0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
WXD1_k127_6121868_1	861299.J421_0381	3.323e-216	702.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
WXD1_k127_6121868_0	861299.J421_0379	8.602e-225	709.0	COG2721@1|root,COG2721@2|Bacteria	2|Bacteria	G	sulfolactate sulfo-lyase activity	uxaA	-	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
WXD1_k127_6121868_5	861299.J421_0378	3.474e-156	507.0	COG0246@1|root,COG0246@2|Bacteria	2|Bacteria	G	mannitol metabolic process	uxaB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0009026,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575	1.1.1.17,1.1.1.58	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00631	R02555,R02703	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c17480	Mannitol_dh,Mannitol_dh_C
WXD1_k127_6121868_3	861299.J421_1197	4.279e-162	528.0	COG1312@1|root,COG1312@2|Bacteria	2|Bacteria	G	mannonate dehydratase activity	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
WXD1_k127_6121868_9	861299.J421_0377	5.603e-87	293.0	COG0800@1|root,COG0800@2|Bacteria	2|Bacteria	G	2-dehydro-3-deoxy-phosphogluconate aldolase activity	eda	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.1.45,4.1.2.14,4.1.3.42	ko:K00874,ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R01541,R05605	RC00002,RC00017,RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
WXD1_k127_6121868_4	861299.J421_0376	1.378e-159	509.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WXD1_k127_6121868_2	861299.J421_0375	1.495e-180	574.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
WXD1_k127_6121868_8	861299.J421_0370	7.322e-108	365.0	COG1028@1|root,COG1028@2|Bacteria,1ZT4H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WXD1_k127_6121868_7	861299.J421_0369	6.581e-119	387.0	COG3717@1|root,COG3717@2|Bacteria	2|Bacteria	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
WXD1_k127_6121868_10	518766.Rmar_2469	1.048e-58	217.0	COG4677@1|root,COG4677@2|Bacteria,4NF12@976|Bacteroidetes	976|Bacteroidetes	G	Domain of unknown function (DUF4861)	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4861
WXD1_k127_6161186_15	1128421.JAGA01000001_gene2063	1.504e-70	250.0	COG0598@1|root,COG0598@2|Bacteria,2NPAW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WXD1_k127_6161186_1	234267.Acid_3931	6.79e-247	796.0	COG2866@1|root,COG2866@2|Bacteria,3Y3X8@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase M14, carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WXD1_k127_6161186_11	945713.IALB_0433	1.204e-113	375.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WXD1_k127_6161186_3	945713.IALB_0434	1.74e-213	683.0	28NE8@1|root,2ZBGT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6161186_18	945713.IALB_0435	4.393e-41	157.0	2CS90@1|root,32SQN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6161186_17	350688.Clos_1346	7.797e-45	174.0	COG2030@1|root,COG2030@2|Bacteria,1V6MY@1239|Firmicutes,24NB6@186801|Clostridia,36M8N@31979|Clostridiaceae	186801|Clostridia	I	PFAM MaoC domain protein dehydratase	-	-	4.2.1.55	ko:K17865	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R03027	RC00831	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
WXD1_k127_6161186_5	518766.Rmar_2447	2.069e-163	546.0	COG0318@1|root,COG0318@2|Bacteria,4NFPF@976|Bacteroidetes,1FJTQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
WXD1_k127_6161186_6	1089550.ATTH01000001_gene429	2.48e-153	500.0	COG4145@1|root,COG4145@2|Bacteria,4PNDF@976|Bacteroidetes,1FJPY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WXD1_k127_6161186_8	264462.Bd0280	4.653e-129	422.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2MSQV@213481|Bdellovibrionales,2WIJN@28221|Deltaproteobacteria	213481|Bdellovibrionales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WXD1_k127_6161186_16	926550.CLDAP_25180	5.877e-56	202.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WXD1_k127_6161186_21	861299.J421_1713	1.858e-12	78.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG1629@2|Bacteria,1ZTMF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MP	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_C
WXD1_k127_6161186_19	379066.GAU_0688	1.639e-27	127.0	COG4632@1|root,COG4632@2|Bacteria,1ZU1E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
WXD1_k127_6161186_10	290512.Paes_0605	2.075e-120	421.0	COG3930@1|root,COG3930@2|Bacteria,1FECR@1090|Chlorobi	1090|Chlorobi	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
WXD1_k127_6161186_14	1120968.AUBX01000001_gene2177	4.399e-91	316.0	COG0189@1|root,COG0189@2|Bacteria,4NED4@976|Bacteroidetes,47TE6@768503|Cytophagia	976|Bacteroidetes	HJ	Prokaryotic glutathione synthetase, N-terminal domain	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
WXD1_k127_6161186_0	861299.J421_3647	2.568e-280	874.0	COG1166@1|root,COG1166@2|Bacteria,1ZST1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
WXD1_k127_6161186_13	404589.Anae109_0505	1.021e-105	350.0	COG0266@1|root,COG0266@2|Bacteria,1MVHK@1224|Proteobacteria,43791@68525|delta/epsilon subdivisions,2X9X0@28221|Deltaproteobacteria,2YZTI@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the FPG family	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WXD1_k127_6161186_4	1242864.D187_001198	8.733e-170	539.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,42R49@68525|delta/epsilon subdivisions,2WNEZ@28221|Deltaproteobacteria,2YU32@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
WXD1_k127_6161186_9	450851.PHZ_c2664	8.722e-128	417.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,2TUGN@28211|Alphaproteobacteria,2KJDM@204458|Caulobacterales	204458|Caulobacterales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WXD1_k127_6161186_7	1254432.SCE1572_39740	7.047e-142	474.0	COG4641@1|root,COG4641@2|Bacteria,1MY6E@1224|Proteobacteria,42YKD@68525|delta/epsilon subdivisions,2WU5I@28221|Deltaproteobacteria,2YUP6@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
WXD1_k127_6161186_12	1254432.SCE1572_39750	6.426e-110	383.0	COG4641@1|root,COG4641@2|Bacteria,1R4AN@1224|Proteobacteria,42PZP@68525|delta/epsilon subdivisions,2WJGG@28221|Deltaproteobacteria,2YZH2@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyl transferases group 1	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
WXD1_k127_6161186_2	596152.DesU5LDRAFT_0871	4.59e-239	755.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,42MKI@68525|delta/epsilon subdivisions,2WM5H@28221|Deltaproteobacteria,2MEEN@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF3459)	treZ-2	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
WXD1_k127_6161186_20	443144.GM21_2540	1.57e-18	95.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
WXD1_k127_616231_3	589865.DaAHT2_1613	2.341e-27	116.0	COG1695@1|root,COG1695@2|Bacteria,1RHG3@1224|Proteobacteria,42UV3@68525|delta/epsilon subdivisions,2WR1W@28221|Deltaproteobacteria,2MNUT@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WXD1_k127_616231_1	504472.Slin_5717	3.514e-90	307.0	COG0451@1|root,COG0451@2|Bacteria,4NG8Y@976|Bacteroidetes,47N8X@768503|Cytophagia	976|Bacteroidetes	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WXD1_k127_616231_5	883.DvMF_1731	7.37e-06	56.0	2AR8A@1|root,31GI0@2|Bacteria,1QE8G@1224|Proteobacteria,43ED8@68525|delta/epsilon subdivisions,2X0DZ@28221|Deltaproteobacteria,2MBZ5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM cytochrome c class III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
WXD1_k127_616231_0	861299.J421_0783	3.415e-159	518.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_9,Response_reg
WXD1_k127_616231_2	640081.Dsui_1554	1.125e-71	265.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVXP@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,Response_reg
WXD1_k127_616231_4	483219.LILAB_10280	5.437e-22	96.0	COG0006@1|root,COG0006@2|Bacteria,1MVHD@1224|Proteobacteria	1224|Proteobacteria	E	Xaa-Pro aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
WXD1_k127_6180877_1	1049564.TevJSym_bb00050	6.527e-234	740.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WXD1_k127_6180877_5	765420.OSCT_0546	6.371e-42	168.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WXD1_k127_6180877_4	1121920.AUAU01000019_gene2602	1.817e-43	171.0	COG1477@1|root,COG1477@2|Bacteria,3Y4B0@57723|Acidobacteria	57723|Acidobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WXD1_k127_6180877_3	1121920.AUAU01000019_gene2603	1.24e-90	327.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K12065	-	-	-	-	ko00000,ko02044	3.A.7.11.1	-	-	Porin_O_P
WXD1_k127_6180877_6	1121920.AUAU01000019_gene2604	5.257e-31	129.0	COG4659@1|root,COG4659@2|Bacteria	2|Bacteria	C	FMN binding	rnfG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
WXD1_k127_6180877_7	379066.GAU_2648	6.779e-29	122.0	COG5349@1|root,COG5349@2|Bacteria,1ZU3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
WXD1_k127_6180877_2	472759.Nhal_2616	3.351e-158	514.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria,1WW9T@135613|Chromatiales	135613|Chromatiales	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
WXD1_k127_6180877_8	1379270.AUXF01000001_gene2733	1.076e-22	103.0	29X7I@1|root,30IWS@2|Bacteria,1ZV88@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WXD1_k127_6180877_0	1379270.AUXF01000001_gene2734	0.0	1455.0	COG0841@1|root,COG0841@2|Bacteria,1ZUDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WXD1_k127_6180877_10	1137281.D778_01198	6.821e-08	57.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,1HZGV@117743|Flavobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WXD1_k127_6185530_0	443144.GM21_1812	4.036e-70	265.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,43T3F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
WXD1_k127_6205887_0	861299.J421_3694	1.183e-307	957.0	COG2183@1|root,COG2183@2|Bacteria,1ZSMQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Tex-like protein N-terminal domain	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
WXD1_k127_6205887_6	861299.J421_6341	4.494e-46	169.0	COG1917@1|root,COG1917@2|Bacteria,1ZTY8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WXD1_k127_6205887_4	861299.J421_6340	4.135e-93	314.0	COG1028@1|root,COG1028@2|Bacteria,1ZTIT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WXD1_k127_6205887_2	861299.J421_1321	2.342e-123	402.0	COG0115@1|root,COG0115@2|Bacteria,1ZTH5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WXD1_k127_6205887_5	1185876.BN8_00865	3.8e-88	309.0	28N78@1|root,2ZBBY@2|Bacteria,4NGF9@976|Bacteroidetes,47X4G@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4932
WXD1_k127_6205887_3	861299.J421_4432	1.189e-117	393.0	COG1502@1|root,COG1502@2|Bacteria,1ZTU6@142182|Gemmatimonadetes	2|Bacteria	I	Phospholipase D. Active site motifs.	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
WXD1_k127_6205887_7	1089545.KB913037_gene8339	3.71e-10	71.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria,4E5JE@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
WXD1_k127_6205887_1	518766.Rmar_1066	2.273e-165	536.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,1FIX6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WXD1_k127_620713_2	93220.LV28_24100	1.097e-42	171.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1K7PD@119060|Burkholderiaceae	28216|Betaproteobacteria	G	peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WXD1_k127_620713_0	1385517.N800_14655	1.208e-75	264.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,1RR4R@1236|Gammaproteobacteria,1X3JH@135614|Xanthomonadales	135614|Xanthomonadales	S	hemolysin III	hly3	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
WXD1_k127_620713_1	1150600.ADIARSV_0164	2.09e-60	216.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPFZ@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2,AA_permease_C
WXD1_k127_6208521_1	1242864.D187_009322	1.978e-151	491.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2X9B9@28221|Deltaproteobacteria,2YX2A@29|Myxococcales	28221|Deltaproteobacteria	P	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
WXD1_k127_6208521_0	861299.J421_2415	2.666e-215	689.0	COG1027@1|root,COG1027@2|Bacteria,1ZT1Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1,cNMP_binding
WXD1_k127_6208521_2	861299.J421_2816	5.469e-96	332.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_7,PAS_9,Response_reg
WXD1_k127_6208521_5	666686.B1NLA3E_14825	2.566e-25	109.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli,1ZH48@1386|Bacillus	91061|Bacilli	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hbs	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WXD1_k127_6208521_3	391037.Sare_2250	6.463e-44	179.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4D933@85008|Micromonosporales	201174|Actinobacteria	L	Belongs to the DEAD box helicase family	deaD	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K05592,ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WXD1_k127_6208521_4	1071679.BG57_03655	3.363e-34	138.0	COG2761@1|root,COG2761@2|Bacteria,1RIE0@1224|Proteobacteria,2W2Y2@28216|Betaproteobacteria,1K4BK@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
WXD1_k127_6208521_6	861299.J421_3646	4.159e-10	71.0	2ENGP@1|root,33G46@2|Bacteria,1ZU71@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
WXD1_k127_622334_0	502025.Hoch_5231	2.977e-108	366.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2YYE4@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WXD1_k127_622334_1	391625.PPSIR1_22374	2.693e-86	294.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,42MGQ@68525|delta/epsilon subdivisions,2WSUN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WXD1_k127_6241244_0	861299.J421_2830	3.265e-109	382.0	COG1629@1|root,COG4771@2|Bacteria,1ZU8C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
WXD1_k127_6241244_1	379066.GAU_3920	2.923e-14	87.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,1ZTYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
WXD1_k127_6265147_2	861299.J421_3134	5.745e-73	273.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
WXD1_k127_6265147_4	477974.Daud_1315	5.97e-58	222.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,261YH@186807|Peptococcaceae	186801|Clostridia	HP	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WXD1_k127_6265147_1	379066.GAU_0496	5.776e-89	305.0	COG0609@1|root,COG0609@2|Bacteria,1ZTAA@142182|Gemmatimonadetes	2|Bacteria	P	FecCD transport family	btuC	-	3.6.3.34	ko:K02013,ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	FecCD
WXD1_k127_6265147_3	379066.GAU_0497	3.684e-61	226.0	COG0614@1|root,COG0614@2|Bacteria,1ZTIM@142182|Gemmatimonadetes	2|Bacteria	P	Periplasmic binding protein	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WXD1_k127_6265147_0	1278073.MYSTI_02808	1.269e-109	364.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria	1224|Proteobacteria	S	major pilin protein fima	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
WXD1_k127_6270634_1	509635.N824_04010	5.788e-132	456.0	COG2982@1|root,COG2982@2|Bacteria,4NEJQ@976|Bacteroidetes,1IRAR@117747|Sphingobacteriia	976|Bacteroidetes	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
WXD1_k127_6270634_0	76114.ebA6736	6.266e-191	610.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
WXD1_k127_6270634_4	1210884.HG799475_gene15209	3.685e-99	355.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_6270634_5	518766.Rmar_1252	1.288e-74	256.0	COG0700@1|root,COG0700@2|Bacteria,4PM62@976|Bacteroidetes,1FJ72@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Nucleoside recognition	-	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
WXD1_k127_6270634_2	518766.Rmar_1253	4.498e-117	385.0	COG2715@1|root,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,1FISA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Nucleoside recognition	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
WXD1_k127_6270634_6	861299.J421_3625	2.298e-45	181.0	COG3118@1|root,COG3118@2|Bacteria,1ZV4B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
WXD1_k127_6270634_3	266117.Rxyl_2946	7.025e-101	359.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
WXD1_k127_6282737_3	326424.FRAAL4955	1.672e-82	286.0	COG5297@1|root,COG5297@2|Bacteria,2GK39@201174|Actinobacteria,4EV09@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	celA1	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Glyco_hydro_6
WXD1_k127_6282737_2	656024.FsymDg_1546	2.437e-96	325.0	COG5297@1|root,COG5297@2|Bacteria,2GK39@201174|Actinobacteria,4EV09@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	celA1	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Glyco_hydro_6
WXD1_k127_6282737_1	379066.GAU_2695	1.231e-103	347.0	COG1234@1|root,COG1234@2|Bacteria,1ZTG7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WXD1_k127_6282737_0	861299.J421_3422	8.929e-132	436.0	COG0128@1|root,COG0128@2|Bacteria	2|Bacteria	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_0998,iECNA114_1301.ECNA114_0940,iECSF_1327.ECSF_0829,iPC815.YPO1390	EPSP_synthase
WXD1_k127_6282737_4	1232436.CAPF01000014_gene748	2.917e-43	167.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CV84@84998|Coriobacteriia	84998|Coriobacteriia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyltransferase,Cytidylate_kin
WXD1_k127_6285358_11	748247.AZKH_2014	1.093e-19	90.0	COG0025@1|root,COG0025@2|Bacteria,1QA7B@1224|Proteobacteria,2VHPR@28216|Betaproteobacteria,2KUTD@206389|Rhodocyclales	206389|Rhodocyclales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WXD1_k127_6285358_7	861299.J421_0471	6.08e-63	228.0	COG2010@1|root,COG2010@2|Bacteria,1ZUJA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6285358_3	216594.MMAR_1307	4.798e-83	287.0	COG2020@1|root,COG2020@2|Bacteria,2GN9N@201174|Actinobacteria,2336J@1762|Mycobacteriaceae	201174|Actinobacteria	O	NnrU protein	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU
WXD1_k127_6285358_2	388051.AUFE01000023_gene4544	5.151e-119	394.0	COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1QYHB@1224|Proteobacteria,2W1S8@28216|Betaproteobacteria,1K5IY@119060|Burkholderiaceae	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
WXD1_k127_6285358_6	760192.Halhy_2423	3.683e-75	261.0	COG1045@1|root,COG1045@2|Bacteria,4NGZ7@976|Bacteroidetes,1IPAM@117747|Sphingobacteriia	976|Bacteroidetes	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
WXD1_k127_6285358_0	861299.J421_6006	1.644e-169	562.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_6285358_4	1121875.KB907550_gene624	7.251e-82	290.0	COG1680@1|root,COG1680@2|Bacteria,4NI1Z@976|Bacteroidetes,1HYQF@117743|Flavobacteriia	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WXD1_k127_6285358_1	1120972.AUMH01000007_gene1617	2.514e-169	542.0	2CA5R@1|root,2Z81H@2|Bacteria,1UYYB@1239|Firmicutes,4HA7J@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
WXD1_k127_6285358_9	1120972.AUMH01000007_gene1618	1.762e-46	178.0	COG1695@1|root,COG1695@2|Bacteria,1VBBY@1239|Firmicutes	1239|Firmicutes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WXD1_k127_6285358_5	426117.M446_0469	5.442e-76	262.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TU0N@28211|Alphaproteobacteria,1JSI3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	MA20_23565	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WXD1_k127_6285358_10	1379270.AUXF01000004_gene2925	6.653e-35	137.0	COG1846@1|root,COG1846@2|Bacteria,1ZU3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
WXD1_k127_6285358_8	1128421.JAGA01000001_gene2144	2.056e-54	204.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WXD1_k127_6296856_8	861299.J421_2523	4.857e-35	136.0	COG0247@1|root,COG0247@2|Bacteria,1ZSTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
WXD1_k127_6296856_3	1382356.JQMP01000004_gene325	8.28e-87	305.0	COG0624@1|root,COG0624@2|Bacteria,2G60R@200795|Chloroflexi,27Y02@189775|Thermomicrobia	189775|Thermomicrobia	E	peptidase dimerisation domain protein	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WXD1_k127_6296856_7	1304874.JAFY01000002_gene911	3.068e-36	157.0	COG2199@1|root,COG3706@2|Bacteria,3TAI8@508458|Synergistetes	508458|Synergistetes	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WXD1_k127_6296856_1	1382306.JNIM01000001_gene1966	8.37e-173	556.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
WXD1_k127_6296856_5	395961.Cyan7425_0687	9.499e-49	192.0	COG2027@1|root,COG2027@2|Bacteria,1G1K9@1117|Cyanobacteria,3KGCK@43988|Cyanothece	1117|Cyanobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WXD1_k127_6296856_6	861299.J421_4225	1.808e-48	185.0	COG1141@1|root,COG1752@1|root,COG1141@2|Bacteria,COG1752@2|Bacteria,1ZT7Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S single cluster domain	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Fer4_15,Patatin
WXD1_k127_6296856_2	533240.CRC_01805	1.714e-94	318.0	COG0396@1|root,COG0396@2|Bacteria,1G11H@1117|Cyanobacteria,1HJ15@1161|Nostocales	1117|Cyanobacteria	O	TIGRFAM FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WXD1_k127_6296856_0	266117.Rxyl_0170	1.972e-229	717.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CPF6@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WXD1_k127_6296856_4	266117.Rxyl_0168	8.404e-86	296.0	COG0719@1|root,COG0719@2|Bacteria,2GJNV@201174|Actinobacteria,4CQXR@84995|Rubrobacteria	84995|Rubrobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
WXD1_k127_6305379_0	1120949.KB903329_gene9217	3.913e-89	326.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,Pkinase
WXD1_k127_6305379_1	1379270.AUXF01000002_gene1756	4.653e-74	267.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
WXD1_k127_6305379_2	1380393.JHVP01000004_gene282	8.097e-29	133.0	COG2261@1|root,COG2261@2|Bacteria,2IQY7@201174|Actinobacteria,4EWID@85013|Frankiales	201174|Actinobacteria	S	transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WXD1_k127_630784_2	1128421.JAGA01000003_gene3454	3.8e-39	164.0	COG3346@1|root,COG3346@2|Bacteria	2|Bacteria	S	mitochondrial respiratory chain complex IV assembly	surf1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
WXD1_k127_630784_4	1298863.AUEP01000014_gene1697	6.234e-13	72.0	2DR0Y@1|root,339QH@2|Bacteria,2GSDX@201174|Actinobacteria,4DS2E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF4235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4235
WXD1_k127_630784_0	861299.J421_2683	2.481e-70	262.0	COG0747@1|root,COG0747@2|Bacteria,1ZTBU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WXD1_k127_630784_3	1173025.GEI7407_1620	3.482e-27	127.0	COG4552@1|root,COG4552@2|Bacteria,1G1E1@1117|Cyanobacteria,1H86G@1150|Oscillatoriales	1117|Cyanobacteria	S	acetyltransferase involved in intracellular survival and related	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
WXD1_k127_630784_1	1379270.AUXF01000004_gene3179	3.183e-39	151.0	COG3876@1|root,COG3876@2|Bacteria,1ZTB6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
WXD1_k127_6318246_5	861299.J421_3849	2.539e-97	338.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WXD1_k127_6318246_7	861299.J421_3854	5.725e-75	267.0	COG0544@1|root,COG0544@2|Bacteria,1ZSSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
WXD1_k127_6318246_6	626939.HMPREF9443_00448	2.279e-80	274.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4H2XP@909932|Negativicutes	909932|Negativicutes	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WXD1_k127_6318246_0	1121430.JMLG01000002_gene1013	4.536e-176	560.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,260QM@186807|Peptococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WXD1_k127_6318246_8	379066.GAU_2413	1.265e-53	196.0	COG0218@1|root,COG0218@2|Bacteria,1ZTHF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
WXD1_k127_6318246_10	1379270.AUXF01000003_gene3510	2.977e-23	107.0	2F4EZ@1|root,33X55@2|Bacteria,1ZTSQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6318246_1	861299.J421_3955	1.019e-146	482.0	COG2204@1|root,COG2204@2|Bacteria,1ZSWY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
WXD1_k127_6318246_9	861299.J421_3956	1.185e-39	154.0	COG0521@1|root,COG0521@2|Bacteria,1ZU2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
WXD1_k127_6318246_2	861299.J421_3957	2.626e-129	422.0	COG0404@1|root,COG0404@2|Bacteria,1ZTBZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WXD1_k127_6318246_3	861299.J421_3960	6.396e-128	421.0	COG0078@1|root,COG0078@2|Bacteria,1ZT4K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WXD1_k127_6318246_4	1379270.AUXF01000003_gene3408	2.306e-118	388.0	COG1220@1|root,COG1220@2|Bacteria,1ZSVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
WXD1_k127_6320801_0	765420.OSCT_1214	1.135e-73	273.0	COG0553@1|root,COG1502@1|root,COG0553@2|Bacteria,COG1502@2|Bacteria,2G6I4@200795|Chloroflexi,376H2@32061|Chloroflexia	32061|Chloroflexia	KL	PFAM helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2
WXD1_k127_6320801_1	1379270.AUXF01000001_gene2637	3.651e-18	96.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1ZT3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LV	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
WXD1_k127_6323557_6	1121468.AUBR01000006_gene365	9.894e-57	220.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,42ERF@68295|Thermoanaerobacterales	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WXD1_k127_6323557_4	861299.J421_3076	1.061e-85	311.0	COG0707@1|root,COG0707@2|Bacteria,1ZSW5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WXD1_k127_6323557_5	768706.Desor_4819	1.109e-77	274.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WXD1_k127_6323557_1	861299.J421_3074	1.513e-120	406.0	COG0771@1|root,COG0771@2|Bacteria,1ZT38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WXD1_k127_6323557_2	861299.J421_3073	8.131e-117	387.0	COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
WXD1_k127_6323557_3	1379270.AUXF01000005_gene686	1.976e-94	328.0	COG0770@1|root,COG0770@2|Bacteria,1ZT1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WXD1_k127_6323557_0	861299.J421_3071	1.002e-156	509.0	COG0769@1|root,COG0769@2|Bacteria,1ZSS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WXD1_k127_6324361_3	1242864.D187_008428	6.992e-14	84.0	COG3918@1|root,COG3918@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
WXD1_k127_6324361_1	1232410.KI421413_gene573	2.108e-48	177.0	COG4276@1|root,COG4276@2|Bacteria,1N6EC@1224|Proteobacteria,42U3N@68525|delta/epsilon subdivisions,2WQTN@28221|Deltaproteobacteria,43VBV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
WXD1_k127_6324361_0	379066.GAU_3326	1.782e-127	422.0	COG2081@1|root,COG2081@2|Bacteria,1ZUAT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WXD1_k127_6324361_2	1121385.AQXW01000004_gene911	1.582e-32	139.0	COG0457@1|root,COG0457@2|Bacteria,2H220@201174|Actinobacteria,1ZWF0@145357|Dermacoccaceae	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
WXD1_k127_6326821_1	1125863.JAFN01000001_gene1060	6.401e-120	411.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_6326821_3	1125863.JAFN01000001_gene973	8.656e-46	186.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42TFH@68525|delta/epsilon subdivisions,2WPEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WXD1_k127_6326821_0	1379698.RBG1_1C00001G0780	7.521e-130	425.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
WXD1_k127_6326821_4	1379698.RBG1_1C00001G0781	1.02e-45	173.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
WXD1_k127_6326821_2	671143.DAMO_0822	2.562e-101	348.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
WXD1_k127_6326821_5	502025.Hoch_3578	2.557e-16	82.0	COG3005@1|root,COG3005@2|Bacteria,1QX4N@1224|Proteobacteria,43BXD@68525|delta/epsilon subdivisions,2X786@28221|Deltaproteobacteria,2Z3DX@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
WXD1_k127_6330147_4	7739.XP_002609587.1	1.307e-08	67.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BDZ9@33208|Metazoa,3CW1H@33213|Bilateria,483Z1@7711|Chordata	33208|Metazoa	S	calcium ion homeostasis	TMTC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_2,TPR_8
WXD1_k127_6330147_3	861299.J421_1152	1.285e-19	98.0	COG4968@1|root,COG4968@2|Bacteria,1ZTWU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WXD1_k127_6330147_1	886293.Sinac_1864	4.776e-62	236.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WXD1_k127_6330147_2	269799.Gmet_0960	6.349e-61	229.0	COG4191@1|root,COG4191@2|Bacteria,1R9AK@1224|Proteobacteria,42Q2G@68525|delta/epsilon subdivisions,2WM8Y@28221|Deltaproteobacteria,43RXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WXD1_k127_6330147_0	448385.sce2881	1.799e-142	470.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_6333125_2	1225184.ALXE01000025_gene2195	1.834e-05	56.0	COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,1RNWK@1236|Gammaproteobacteria,3VY1P@53335|Pantoea	1236|Gammaproteobacteria	NU	fimbrial biogenesis outer membrane usher protein	csuD	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	PapC_C,Usher
WXD1_k127_6333125_1	338963.Pcar_2058	8.498e-44	169.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
WXD1_k127_6333125_0	358220.C380_21310	1.286e-156	499.0	COG3000@1|root,COG3714@1|root,COG3000@2|Bacteria,COG3714@2|Bacteria,1NR7X@1224|Proteobacteria,2VJ4E@28216|Betaproteobacteria,4ABMB@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase,YhhN
WXD1_k127_6358839_3	861299.J421_3849	1.953e-81	291.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WXD1_k127_6358839_10	1379270.AUXF01000006_gene52	1.865e-20	98.0	COG5608@1|root,COG5608@2|Bacteria,1ZTWB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
WXD1_k127_6358839_2	861299.J421_3506	5.922e-135	443.0	COG2262@1|root,COG2262@2|Bacteria,1ZSYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WXD1_k127_6358839_9	429009.Adeg_1878	4.284e-37	154.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,42G5H@68295|Thermoanaerobacterales	186801|Clostridia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
WXD1_k127_6358839_4	595460.RRSWK_02418	5.217e-76	262.0	COG0854@1|root,COG0854@2|Bacteria,2IYJ4@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
WXD1_k127_6358839_12	861299.J421_2970	0.0004714	52.0	2CB0K@1|root,343GC@2|Bacteria,1ZU4A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
WXD1_k127_6358839_7	379066.GAU_1245	1.838e-49	194.0	COG0392@1|root,COG0392@2|Bacteria,1ZT5W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WXD1_k127_6358839_5	861299.J421_2968	5.259e-53	198.0	COG1947@1|root,COG1947@2|Bacteria,1ZTM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
WXD1_k127_6358839_11	1379270.AUXF01000001_gene2791	0.000105	52.0	2FK78@1|root,34BUZ@2|Bacteria,1ZU15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6358839_1	379066.GAU_1219	8.896e-136	439.0	COG0462@1|root,COG0462@2|Bacteria,1ZT7Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WXD1_k127_6358839_8	861299.J421_2966	4.339e-40	157.0	COG1825@1|root,COG1825@2|Bacteria,1ZTHZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	-	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WXD1_k127_6358839_6	861299.J421_2965	2.903e-50	185.0	COG0193@1|root,COG0193@2|Bacteria,1ZTKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WXD1_k127_6358839_0	522772.Dacet_0072	1.752e-248	785.0	COG3808@1|root,COG3808@2|Bacteria,2GFAJ@200930|Deferribacteres	200930|Deferribacteres	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
WXD1_k127_6374717_0	309807.SRU_0093	7.453e-132	441.0	COG2352@1|root,COG2352@2|Bacteria,4NFC0@976|Bacteroidetes,1FJ49@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
WXD1_k127_6374717_2	1385517.N800_09725	1.088e-17	88.0	COG1652@1|root,COG1652@2|Bacteria,1N3P8@1224|Proteobacteria,1SY85@1236|Gammaproteobacteria,1X82C@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidoglycan-binding protein, lysm	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WXD1_k127_6374717_1	1121015.N789_08450	3.838e-28	119.0	2AQTF@1|root,31G1I@2|Bacteria,1QDTY@1224|Proteobacteria,1T9Z0@1236|Gammaproteobacteria,1X8GI@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6375390_2	1144275.COCOR_03705	6.472e-15	81.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2YUH8@29|Myxococcales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
WXD1_k127_6375390_0	945713.IALB_0006	2.78e-314	985.0	COG0188@1|root,COG0188@2|Bacteria	2|Bacteria	L	DNA topoisomerase II activity	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WXD1_k127_6375390_1	861299.J421_2397	4.776e-75	264.0	COG1171@1|root,COG1171@2|Bacteria,1ZTBP@142182|Gemmatimonadetes	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WXD1_k127_6378178_15	861299.J421_4240	1.546e-06	59.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
WXD1_k127_6378178_6	1173020.Cha6605_1569	9.582e-57	205.0	COG0454@1|root,COG0456@2|Bacteria,1GCDA@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.60	ko:K03395	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WXD1_k127_6378178_4	1379270.AUXF01000002_gene1136	1.796e-74	263.0	COG1137@1|root,COG1137@2|Bacteria	2|Bacteria	S	lipopolysaccharide-transporting ATPase activity	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
WXD1_k127_6378178_9	216595.PFLU_0196	6.407e-47	182.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RN7K@1236|Gammaproteobacteria,1YNQC@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
WXD1_k127_6378178_1	1408254.T458_20775	1.288e-77	272.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
WXD1_k127_6378178_13	1379270.AUXF01000002_gene1135	7.355e-29	124.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WXD1_k127_6378178_0	861299.J421_1762	6.217e-182	580.0	COG1409@1|root,COG1409@2|Bacteria,1ZUD8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WXD1_k127_6378178_14	1122604.JONR01000003_gene1363	1.708e-21	106.0	COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,1S9AT@1236|Gammaproteobacteria,1XCII@135614|Xanthomonadales	135614|Xanthomonadales	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
WXD1_k127_6378178_11	861299.J421_1097	3.611e-45	169.0	COG2318@1|root,COG2318@2|Bacteria,1ZV4X@142182|Gemmatimonadetes	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
WXD1_k127_6378178_12	1029824.AFID01000002_gene1429	3.371e-40	155.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria,1W9DB@1268|Micrococcaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WXD1_k127_6378178_7	869213.JCM21142_104172	3.585e-55	202.0	COG1794@1|root,COG1794@2|Bacteria,4NI4F@976|Bacteroidetes,47UIB@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
WXD1_k127_6378178_5	1238182.C882_2913	3.228e-67	237.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,2JSHV@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WXD1_k127_6378178_3	452637.Oter_0578	1.161e-75	264.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WXD1_k127_6378178_8	1267535.KB906767_gene1546	4.82e-50	191.0	COG3132@1|root,COG3132@2|Bacteria,3Y50M@57723|Acidobacteria,2JMSB@204432|Acidobacteriia	204432|Acidobacteriia	S	Belongs to the UPF0502 family	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
WXD1_k127_6378178_10	1134912.AJTV01000001_gene1457	9.913e-47	175.0	2DB7V@1|root,2Z7NX@2|Bacteria,1N9SI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6387784_1	379066.GAU_1130	1.545e-90	323.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WXD1_k127_6387784_0	1379270.AUXF01000005_gene400	1.111e-105	356.0	COG1104@1|root,COG1104@2|Bacteria,1ZSXD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WXD1_k127_6407917_2	204669.Acid345_4456	2.214e-38	156.0	COG2764@1|root,COG2764@2|Bacteria,3Y5JW@57723|Acidobacteria,2JK34@204432|Acidobacteriia	204432|Acidobacteriia	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
WXD1_k127_6407917_1	1054213.HMPREF9946_03374	1.423e-40	156.0	29IJ4@1|root,305GB@2|Bacteria,1N0FK@1224|Proteobacteria,2UDQU@28211|Alphaproteobacteria,2JU5M@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
WXD1_k127_6407917_0	1379270.AUXF01000001_gene2386	1.337e-68	237.0	COG1896@1|root,COG1896@2|Bacteria,1ZU77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
WXD1_k127_6410512_3	1117314.PCIT_06360	0.0007563	44.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,2Q185@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Zn-dependent peptidases	ptrA	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_6410512_0	391625.PPSIR1_22471	2.887e-117	396.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YXKT@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_6410512_1	234267.Acid_3612	1.013e-15	91.0	2E3HM@1|root,32W74@2|Bacteria,3Y85J@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6410512_2	1035308.AQYY01000001_gene3506	0.000127	53.0	2CIBE@1|root,32S7P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6427898_14	1298867.AUES01000022_gene2827	2.699e-30	122.0	COG4221@1|root,COG4221@2|Bacteria,1MW86@1224|Proteobacteria,2TSEM@28211|Alphaproteobacteria,3JSMN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	MA20_04540	-	-	-	-	-	-	-	-	-	-	-	adh_short
WXD1_k127_6427898_10	1379270.AUXF01000001_gene2409	2.814e-45	171.0	COG1595@1|root,COG1595@2|Bacteria,1ZTJF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_6427898_20	861299.J421_2115	1.385e-17	94.0	2F7PW@1|root,34048@2|Bacteria,1ZTZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6427898_25	1121949.AQXT01000002_gene1084	1.685e-05	57.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,43X8X@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Belongs to the peptidase S1C family	dop	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WXD1_k127_6427898_22	868864.Dester_0544	1.455e-08	66.0	COG0265@1|root,COG0265@2|Bacteria,2G3MU@200783|Aquificae	200783|Aquificae	M	PFAM peptidase S1 and S6 chymotrypsin Hap	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WXD1_k127_6427898_11	1089550.ATTH01000001_gene1932	3.757e-40	163.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
WXD1_k127_6427898_16	765420.OSCT_0889	6.604e-27	126.0	COG1232@1|root,COG1232@2|Bacteria	2|Bacteria	H	protoporphyrinogen oxidase activity	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
WXD1_k127_6427898_21	861299.J421_2615	6.89e-09	61.0	COG4123@1|root,COG4123@2|Bacteria,1ZTJ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6427898_23	1379270.AUXF01000002_gene1165	2.427e-08	66.0	COG1729@1|root,COG3087@1|root,COG1729@2|Bacteria,COG3087@2|Bacteria,1ZTSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_6
WXD1_k127_6427898_17	379066.GAU_3913	3.491e-26	120.0	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WXD1_k127_6427898_24	1379270.AUXF01000002_gene1167	1.296e-06	59.0	2FFVA@1|root,347SB@2|Bacteria,1ZTX8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6427898_5	861299.J421_0907	5.488e-87	292.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_6427898_8	861299.J421_0908	5.697e-70	241.0	COG0494@1|root,COG0494@2|Bacteria,1ZTQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WXD1_k127_6427898_3	861299.J421_0915	1.035e-109	378.0	COG0612@1|root,COG0612@2|Bacteria,1ZT9J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_6427898_0	861299.J421_0916	1.045e-139	467.0	COG0612@1|root,COG0612@2|Bacteria,1ZSVK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_6427898_7	861299.J421_0927	8.52e-75	274.0	COG0612@1|root,COG0612@2|Bacteria,1ZT6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_6427898_2	1191523.MROS_1496	9.359e-122	417.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WXD1_k127_6427898_12	935567.JAES01000025_gene1230	1.92e-35	145.0	COG1434@1|root,COG1434@2|Bacteria,1N0Q9@1224|Proteobacteria,1S98Q@1236|Gammaproteobacteria,1X5HX@135614|Xanthomonadales	135614|Xanthomonadales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WXD1_k127_6427898_26	404589.Anae109_0141	0.0005513	51.0	COG0457@1|root,COG3824@1|root,COG0457@2|Bacteria,COG3824@2|Bacteria	2|Bacteria	S	Zincin-like metallopeptidase	MA20_43655	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Zincin_1
WXD1_k127_6427898_1	56780.SYN_02641	5.049e-128	420.0	COG3635@1|root,COG3635@2|Bacteria,1R4TM@1224|Proteobacteria	1224|Proteobacteria	G	metalloenzyme domain protein	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
WXD1_k127_6427898_6	864069.MicloDRAFT_00047050	4.64e-82	286.0	COG0436@1|root,COG0436@2|Bacteria,1MX43@1224|Proteobacteria,2TV9C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WXD1_k127_6427898_18	1346330.M472_11065	5.504e-22	106.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	ykuD	-	-	ko:K19234	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,YkuD
WXD1_k127_6427898_19	1161401.ASJA01000018_gene1224	1.508e-20	100.0	COG0784@1|root,COG0784@2|Bacteria,1QU3I@1224|Proteobacteria,2TVXW@28211|Alphaproteobacteria,440RB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WXD1_k127_6427898_13	1463900.JOIX01000003_gene1001	3.471e-32	141.0	COG0515@1|root,COG0515@2|Bacteria,2IAFS@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WXD1_k127_6427898_15	861299.J421_2716	2.48e-28	119.0	COG0745@1|root,COG0745@2|Bacteria	861299.J421_2716|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6427898_9	1125863.JAFN01000001_gene792	9.022e-50	183.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
WXD1_k127_6427898_4	234267.Acid_6478	1.3e-108	357.0	COG1136@1|root,COG1136@2|Bacteria,3Y2X0@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WXD1_k127_642861_0	521098.Aaci_1231	2.039e-130	445.0	COG0111@1|root,COG2150@1|root,COG0111@2|Bacteria,COG2150@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli,2784J@186823|Alicyclobacillaceae	91061|Bacilli	E	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
WXD1_k127_642861_3	379066.GAU_0192	8.483e-94	326.0	COG0075@1|root,COG0075@2|Bacteria,1ZTF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WXD1_k127_642861_4	1000565.METUNv1_01440	1.348e-37	153.0	COG0560@1|root,COG0560@2|Bacteria	2|Bacteria	E	Phosphoserine phosphatase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD,Hydrolase
WXD1_k127_642861_1	357808.RoseRS_3819	6.384e-98	334.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WXD1_k127_642861_5	1266925.JHVX01000003_gene496	4.129e-18	95.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,2WBDF@28216|Betaproteobacteria,372WN@32003|Nitrosomonadales	28216|Betaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
WXD1_k127_642861_2	661478.OP10G_0240	3.67e-97	351.0	COG1626@1|root,COG1626@2|Bacteria	2|Bacteria	G	alpha,alpha-trehalase activity	ygjK	GO:0003674,GO:0003824,GO:0004553,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015926,GO:0016787,GO:0016798,GO:0033554,GO:0050896,GO:0051716	3.2.1.28	ko:K01194,ko:K03931	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37,GH63	-	Glyco_hydro_63,Trehalase
WXD1_k127_642861_6	880073.Calab_0032	1.554e-05	55.0	COG3408@1|root,COG3408@2|Bacteria,2NPYR@2323|unclassified Bacteria	2|Bacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,GDE_C,GDE_N_bis
WXD1_k127_6429517_15	1041930.Mtc_1553	0.0001746	48.0	COG2968@1|root,arCOG04715@2157|Archaea,2XZAZ@28890|Euryarchaeota,2N9TF@224756|Methanomicrobia	224756|Methanomicrobia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
WXD1_k127_6429517_4	861299.J421_3942	9.013e-124	410.0	COG1208@1|root,COG1208@2|Bacteria,1ZSYR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WXD1_k127_6429517_7	861299.J421_3941	5.862e-87	301.0	COG0624@1|root,COG0624@2|Bacteria,1ZTIX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WXD1_k127_6429517_3	1192034.CAP_5366	1.905e-140	458.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YTZB@29|Myxococcales	28221|Deltaproteobacteria	E	synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
WXD1_k127_6429517_11	383372.Rcas_2368	1.752e-32	136.0	COG2947@1|root,COG2947@2|Bacteria,2G93S@200795|Chloroflexi,375T3@32061|Chloroflexia	32061|Chloroflexia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
WXD1_k127_6429517_13	28444.JODQ01000002_gene4055	6.643e-21	98.0	COG0745@1|root,COG0745@2|Bacteria,2I2Z1@201174|Actinobacteria,4EJHI@85012|Streptosporangiales	201174|Actinobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WXD1_k127_6429517_1	246197.MXAN_0378	3.78e-156	503.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2YWVA@29|Myxococcales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WXD1_k127_6429517_0	379066.GAU_2362	2.516e-241	778.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1ZT3K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
WXD1_k127_6429517_2	379066.GAU_2363	8.861e-146	484.0	COG5492@1|root,COG5492@2|Bacteria,1ZSN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6429517_12	1379270.AUXF01000003_gene3563	8.204e-25	113.0	2ES4T@1|root,33JPM@2|Bacteria,1ZU4W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6429517_10	1379270.AUXF01000003_gene3568	4.285e-79	272.0	COG0745@1|root,COG0745@2|Bacteria,1ZTC6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WXD1_k127_6429517_9	861299.J421_3841	1.67e-79	288.0	COG5002@1|root,COG5002@2|Bacteria,1ZT2H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WXD1_k127_6429517_14	693979.Bache_1368	9.953e-05	54.0	COG3746@1|root,COG3746@2|Bacteria,4NI6X@976|Bacteroidetes,2FPGI@200643|Bacteroidia,4AM4H@815|Bacteroidaceae	976|Bacteroidetes	P	Psort location OuterMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
WXD1_k127_6429517_6	555079.Toce_0354	5.461e-110	364.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,42EPR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM extracellular solute-binding protein family 1	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	Big_5,PBP_like_2
WXD1_k127_6429517_5	1444309.JAQG01000110_gene1803	7.516e-112	370.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,26SNZ@186822|Paenibacillaceae	91061|Bacilli	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WXD1_k127_6429517_8	1031288.AXAA01000018_gene32	5.12e-84	300.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,36DCX@31979|Clostridiaceae	186801|Clostridia	P	Phosphate transport system permease protein PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
WXD1_k127_643440_1	379066.GAU_3069	4.94e-48	176.0	COG0681@1|root,COG0681@2|Bacteria,1ZTFC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
WXD1_k127_643440_0	861299.J421_4450	1.399e-139	456.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WXD1_k127_6437733_2	595536.ADVE02000001_gene446	2.54e-24	116.0	COG0438@1|root,COG0438@2|Bacteria,1MVT0@1224|Proteobacteria,2U2ZR@28211|Alphaproteobacteria,36ZVA@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glycos_transf_1
WXD1_k127_6437733_0	1173023.KE650771_gene5116	1.89e-85	306.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
WXD1_k127_6437733_1	1242864.D187_003367	1.743e-53	196.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2Z03M@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WXD1_k127_6437733_3	1304872.JAGC01000003_gene3490	3.258e-06	58.0	COG0438@1|root,COG0438@2|Bacteria,1R11H@1224|Proteobacteria,43D5I@68525|delta/epsilon subdivisions,2X8C9@28221|Deltaproteobacteria,2M8ZK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
WXD1_k127_6443956_2	1379270.AUXF01000001_gene2066	1.102e-48	195.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
WXD1_k127_6443956_3	269799.Gmet_2816	1.998e-13	83.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria,43TQ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WXD1_k127_6443956_1	1123278.KB893419_gene1221	2.614e-52	204.0	COG0823@1|root,COG0823@2|Bacteria,4NITC@976|Bacteroidetes,47R0N@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	PD40
WXD1_k127_6443956_0	1379270.AUXF01000001_gene2066	4.721e-76	269.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
WXD1_k127_6443956_4	398767.Glov_2040	6.941e-09	68.0	COG1413@1|root,COG1413@2|Bacteria,1N5TU@1224|Proteobacteria,42UDF@68525|delta/epsilon subdivisions,2WQ3K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WXD1_k127_6457899_0	861299.J421_0487	4.815e-312	968.0	COG2936@1|root,COG2936@2|Bacteria,1ZUE2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WXD1_k127_6457899_2	1122137.AQXF01000005_gene1230	1.116e-26	123.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	SGL
WXD1_k127_6457899_1	290397.Adeh_4303	8.048e-30	135.0	COG0451@1|root,COG0451@2|Bacteria,1MWYB@1224|Proteobacteria,43DY0@68525|delta/epsilon subdivisions,2X918@28221|Deltaproteobacteria,2Z1ER@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WXD1_k127_6462769_0	290315.Clim_1171	9.744e-104	344.0	COG2267@1|root,COG2267@2|Bacteria,1FEF1@1090|Chlorobi	1090|Chlorobi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WXD1_k127_6462769_1	1227349.C170_28688	1.047e-08	66.0	COG1523@1|root,COG5492@1|root,COG1523@2|Bacteria,COG5492@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli,26QXV@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Big_2,Big_5,CBM_48,DUF3372,PUD,SLH
WXD1_k127_6469282_5	1082705.JIBP01000003_gene2319	8.964e-09	59.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008703,GO:0008835,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.1.1.193,3.5.4.26	ko:K01498,ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00366,iECBD_1354.ECBD_3247,iECB_1328.ECB_00362,iECD_1391.ECD_00362,iECED1_1282.ECED1_0437,iECNA114_1301.ECNA114_0391,iECSF_1327.ECSF_0374,iEcolC_1368.EcolC_3219,iJN746.PP_0514,iLF82_1304.LF82_1880,iNRG857_1313.NRG857_01945,iYL1228.KPN_00366,ic_1306.c0524	RibD_C,dCMP_cyt_deam_1
WXD1_k127_6469282_4	573370.DMR_05620	4.438e-16	86.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,2M819@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
WXD1_k127_6469282_3	1379270.AUXF01000005_gene722	9.911e-25	115.0	2F30H@1|root,33VVT@2|Bacteria,1ZTRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6469282_1	1379270.AUXF01000005_gene721	6.746e-114	376.0	COG0150@1|root,COG0150@2|Bacteria,1ZSQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WXD1_k127_6469282_0	861299.J421_3111	1.166e-121	399.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WXD1_k127_6469282_2	861299.J421_3110	1.899e-54	198.0	COG0018@1|root,COG0018@2|Bacteria,1ZT6E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WXD1_k127_6472681_0	1278073.MYSTI_07864	1.266e-225	730.0	COG0577@1|root,COG0577@2|Bacteria,1NREW@1224|Proteobacteria	1224|Proteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
WXD1_k127_6472681_1	1278073.MYSTI_07863	1.232e-34	149.0	COG1695@1|root,COG1695@2|Bacteria,1PMEN@1224|Proteobacteria,43544@68525|delta/epsilon subdivisions,2WZF7@28221|Deltaproteobacteria,2Z209@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WXD1_k127_6472681_2	379066.GAU_1959	1.707e-33	140.0	2EQJ9@1|root,33I5A@2|Bacteria,1ZTSN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6472681_3	861299.J421_1376	2.996e-33	145.0	2AER0@1|root,314MK@2|Bacteria,1ZTTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6478546_1	204669.Acid345_2963	3.046e-139	455.0	COG2301@1|root,COG3052@1|root,COG2301@2|Bacteria,COG3052@2|Bacteria,3Y8FI@57723|Acidobacteria,2JNED@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
WXD1_k127_6478546_0	204669.Acid345_2962	4.588e-256	820.0	COG3051@1|root,COG3051@2|Bacteria	2|Bacteria	C	citrate CoA-transferase activity	citF	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	CitF
WXD1_k127_6478611_1	1158760.AQXP01000033_gene974	4.002e-64	239.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales	135613|Chromatiales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WXD1_k127_6478611_4	1379270.AUXF01000003_gene3575	1.061e-50	189.0	COG0566@1|root,COG0566@2|Bacteria,1ZTVA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNA 2'-O ribose methyltransferase substrate binding	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WXD1_k127_6478611_3	379066.GAU_2351	7.323e-52	203.0	COG1989@1|root,COG1989@2|Bacteria,1ZT9K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WXD1_k127_6478611_2	78245.Xaut_2223	2.798e-61	223.0	COG0665@1|root,COG0665@2|Bacteria,1N1TN@1224|Proteobacteria,2TR7B@28211|Alphaproteobacteria,3F043@335928|Xanthobacteraceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
WXD1_k127_6478611_0	518766.Rmar_0272	2.273e-71	249.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
WXD1_k127_6487630_3	439497.RR11_2496	0.0008138	45.0	COG2931@1|root,COG2931@2|Bacteria,1R0A0@1224|Proteobacteria,2TYP4@28211|Alphaproteobacteria,4NDQN@97050|Ruegeria	2|Bacteria	Q	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,VCBS
WXD1_k127_6487630_1	1128421.JAGA01000002_gene1771	2.749e-32	135.0	COG1158@1|root,COG1158@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WXD1_k127_6490326_0	379066.GAU_2809	2.061e-89	318.0	COG0501@1|root,COG0501@2|Bacteria,1ZSNK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
WXD1_k127_6490326_1	861299.J421_2339	1.499e-40	170.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	2|Bacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
WXD1_k127_6490876_4	861299.J421_2596	3.083e-11	74.0	2EW4E@1|root,33PHK@2|Bacteria,1ZT53@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6490876_0	1379270.AUXF01000004_gene3232	5.164e-161	518.0	COG2204@1|root,COG2204@2|Bacteria,1ZSW0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_6490876_2	1379270.AUXF01000004_gene3229	1.399e-63	236.0	COG5000@1|root,COG5000@2|Bacteria,1ZTBX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WXD1_k127_6490876_3	861299.J421_2675	1.316e-48	183.0	2ED0A@1|root,336X9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6490876_1	1123242.JH636435_gene1379	5.852e-73	253.0	COG3386@1|root,COG3386@2|Bacteria,2IZFH@203682|Planctomycetes	203682|Planctomycetes	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
WXD1_k127_6493644_0	861299.J421_2845	6.919e-123	427.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSWP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
WXD1_k127_6493893_9	1121939.L861_20175	3.998e-77	269.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1SPFG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
WXD1_k127_6493893_6	1123023.JIAI01000002_gene5544	1.867e-129	430.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4DZXW@85010|Pseudonocardiales	201174|Actinobacteria	S	Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma- L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine	egtB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0019439,GO:0019752,GO:0034641,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0055114,GO:0071704,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase
WXD1_k127_6493893_10	1463934.JOCF01000009_gene4698	1.142e-73	276.0	COG4301@1|root,COG4301@2|Bacteria,2GJAX@201174|Actinobacteria	201174|Actinobacteria	S	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
WXD1_k127_6493893_12	861299.J421_2501	3.018e-46	174.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	HSP70
WXD1_k127_6493893_7	93220.LV28_24155	1.025e-112	375.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,1JZZX@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WXD1_k127_6493893_0	861299.J421_2685	0.0	1330.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1ZSUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
WXD1_k127_6493893_14	379066.GAU_0620	4.209e-27	127.0	COG0526@1|root,COG0526@2|Bacteria,1ZTMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WXD1_k127_6493893_5	1089550.ATTH01000001_gene359	6.483e-130	428.0	COG5505@1|root,COG5505@2|Bacteria,4NE2H@976|Bacteroidetes,1FJQG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
WXD1_k127_6493893_1	211586.SO_2494	9.196e-249	807.0	COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,1RS2Q@1236|Gammaproteobacteria,2QANN@267890|Shewanellaceae	1236|Gammaproteobacteria	E	PFAM peptidase M2, peptidyl-dipeptidase A	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
WXD1_k127_6493893_8	379066.GAU_2541	1.929e-110	370.0	COG0389@1|root,COG0389@2|Bacteria,1ZT65@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
WXD1_k127_6493893_13	1120980.JQKH01000026_gene1672	2.54e-29	127.0	2E03A@1|root,32VS4@2|Bacteria,1N4NZ@1224|Proteobacteria,2W2X8@28216|Betaproteobacteria,2KT1U@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6493893_3	1461693.ATO10_09273	1.342e-148	500.0	COG0682@1|root,COG0682@2|Bacteria,1R7B3@1224|Proteobacteria	1224|Proteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT,PAP2_3,PEMT
WXD1_k127_6493893_11	1128421.JAGA01000003_gene2936	1.303e-60	235.0	COG0506@1|root,COG0506@2|Bacteria,2NPED@2323|unclassified Bacteria	2|Bacteria	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
WXD1_k127_6493893_2	1144275.COCOR_03147	9.467e-155	514.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,4360M@68525|delta/epsilon subdivisions,2X2HZ@28221|Deltaproteobacteria,2Z0WC@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WXD1_k127_6493893_4	518766.Rmar_2666	5.719e-131	429.0	COG3004@1|root,COG3004@2|Bacteria,4NFC4@976|Bacteroidetes	976|Bacteroidetes	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
WXD1_k127_6498571_11	1121101.HMPREF1532_00139	6.669e-20	98.0	COG0110@1|root,COG0110@2|Bacteria,4NMHW@976|Bacteroidetes,2FPDD@200643|Bacteroidia,4AMEE@815|Bacteroidaceae	976|Bacteroidetes	S	Psort location Cytoplasmic, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
WXD1_k127_6498571_6	530564.Psta_3827	9.046e-53	195.0	COG0457@1|root,COG0457@2|Bacteria	530564.Psta_3827|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6498571_12	1385513.N780_13515	9.473e-14	83.0	COG3153@1|root,COG3153@2|Bacteria,1V0I4@1239|Firmicutes,4HCMH@91061|Bacilli,2YB6D@289201|Pontibacillus	91061|Bacilli	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WXD1_k127_6498571_14	219305.MCAG_01473	6.024e-06	59.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4DAC6@85008|Micromonosporales	201174|Actinobacteria	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WXD1_k127_6498571_8	596152.DesU5LDRAFT_2515	1.252e-47	187.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,42M2P@68525|delta/epsilon subdivisions,2WM2M@28221|Deltaproteobacteria,2MD72@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_6498571_7	448385.sce7019	3.021e-48	187.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria	1224|Proteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WXD1_k127_6498571_4	443152.MDG893_06104	2.286e-68	252.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria,465WK@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WXD1_k127_6498571_1	349521.HCH_02727	1.434e-95	330.0	COG3307@1|root,COG3307@2|Bacteria,1PFDH@1224|Proteobacteria,1TAJ1@1236|Gammaproteobacteria,1XQQM@135619|Oceanospirillales	135619|Oceanospirillales	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WXD1_k127_6498571_2	396588.Tgr7_2376	2.029e-76	276.0	COG3919@1|root,COG3919@2|Bacteria,1R94Z@1224|Proteobacteria,1RQ74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,LMWPc
WXD1_k127_6498571_5	404380.Gbem_1793	6.885e-67	244.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42PY9@68525|delta/epsilon subdivisions,2WMGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	coenzyme F390	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Glycos_transf_2
WXD1_k127_6498571_3	396588.Tgr7_2362	1.045e-69	254.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,1RPB8@1236|Gammaproteobacteria,1WWKU@135613|Chromatiales	135613|Chromatiales	M	Sugar transferase, PEP-CTERM EpsH1 system associated	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
WXD1_k127_6498571_0	396588.Tgr7_2360	1.464e-129	436.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria,1WWE5@135613|Chromatiales	135613|Chromatiales	E	Asparagine synthase, glutamine-hydrolyzing	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
WXD1_k127_6498571_10	1242864.D187_002821	7.765e-25	123.0	COG4733@1|root,COG4733@2|Bacteria,1QX65@1224|Proteobacteria,43BYR@68525|delta/epsilon subdivisions,2X79M@28221|Deltaproteobacteria,2YZ8E@29|Myxococcales	28221|Deltaproteobacteria	G	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WXD1_k127_6498571_9	383372.Rcas_2855	2.151e-32	147.0	COG3391@1|root,COG4935@1|root,COG3391@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF11,P_proprotein,Peptidase_S8,Reprolysin_3
WXD1_k127_6498571_13	552396.HMPREF0863_02649	1.614e-09	71.0	COG3757@1|root,COG5492@1|root,COG3757@2|Bacteria,COG5492@2|Bacteria,1V4A5@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
WXD1_k127_6499583_0	251221.35211322	0.0	1155.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
WXD1_k127_6499583_1	309807.SRU_1701	6.186e-186	602.0	COG1960@1|root,COG3793@1|root,COG1960@2|Bacteria,COG3793@2|Bacteria,4NF87@976|Bacteroidetes,1FJZY@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IP	Acyl-CoA oxidase	-	-	1.3.3.6	ko:K00232	ko00071,ko00592,ko01040,ko01100,ko01110,ko01212,ko03320,ko04024,ko04146,map00071,map00592,map01040,map01100,map01110,map01212,map03320,map04024,map04146	M00087,M00113	R01175,R01279,R03777,R03857,R03990,R04751,R04754,R07888,R07892,R07896,R07934,R07950	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	ACOX,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WXD1_k127_6499583_3	649638.Trad_1219	1.082e-93	325.0	COG4850@1|root,COG4850@2|Bacteria,1WMEC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
WXD1_k127_6499583_2	1123508.JH636441_gene3431	5.582e-105	362.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
WXD1_k127_6500676_0	861299.J421_6370	0.0	1022.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1ZTGF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CH	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
WXD1_k127_6500676_2	1300345.LF41_1864	6.883e-124	417.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T234@1236|Gammaproteobacteria,1X903@135614|Xanthomonadales	135614|Xanthomonadales	S	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
WXD1_k127_6500676_1	1549858.MC45_07405	5.839e-247	790.0	COG0308@1|root,COG0308@2|Bacteria,1PJTM@1224|Proteobacteria,2U2D3@28211|Alphaproteobacteria,2K1XV@204457|Sphingomonadales	204457|Sphingomonadales	E	ERAP1-like C-terminal domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
WXD1_k127_6511450_0	861299.J421_6229	0.0	1870.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1,Thiol-ester_cl
WXD1_k127_6511450_2	395961.Cyan7425_1218	6.794e-151	505.0	COG0477@1|root,COG2814@2|Bacteria,1G1K4@1117|Cyanobacteria,3KHI5@43988|Cyanothece	1117|Cyanobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn,MFS_1
WXD1_k127_6511450_3	1379270.AUXF01000001_gene2530	9.65e-66	237.0	COG1131@1|root,COG1131@2|Bacteria,1ZV1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_6511450_4	1379270.AUXF01000001_gene2529	7.314e-43	161.0	COG1725@1|root,COG1725@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
WXD1_k127_6511450_1	861299.J421_3663	3.054e-155	500.0	COG1228@1|root,COG1228@2|Bacteria,1ZSU7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WXD1_k127_6514919_3	861299.J421_3548	1.622e-49	192.0	COG0805@1|root,COG0805@2|Bacteria,1ZTHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WXD1_k127_6514919_4	1379698.RBG1_1C00001G1448	2.039e-45	169.0	COG1327@1|root,COG1327@2|Bacteria,2NPEU@2323|unclassified Bacteria	2|Bacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WXD1_k127_6514919_10	443143.GM18_0572	1.346e-05	56.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,43URZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
WXD1_k127_6514919_6	861299.J421_3550	7.607e-36	155.0	COG2885@1|root,COG2885@2|Bacteria,1ZTSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
WXD1_k127_6514919_2	379066.GAU_1942	9.05e-60	231.0	COG0823@1|root,COG0823@2|Bacteria,1ZTBK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WXD1_k127_6514919_9	861299.J421_3552	4.703e-20	103.0	COG0810@1|root,COG0810@2|Bacteria,1ZTWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
WXD1_k127_6514919_8	379066.GAU_1944	1.591e-21	106.0	COG0848@1|root,COG0848@2|Bacteria,1ZTRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
WXD1_k127_6514919_5	1379270.AUXF01000006_gene14	7.202e-41	164.0	COG0811@1|root,COG0811@2|Bacteria,1ZTBF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
WXD1_k127_6514919_0	379066.GAU_1946	3.112e-99	333.0	COG1087@1|root,COG1087@2|Bacteria,1ZSX3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WXD1_k127_6514919_1	644966.Tmar_1263	6.953e-96	331.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
WXD1_k127_6514919_7	1125863.JAFN01000001_gene1124	8.409e-22	106.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
WXD1_k127_6519707_3	861299.J421_3896	3.001e-149	490.0	COG0626@1|root,COG0626@2|Bacteria,1ZT9F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
WXD1_k127_6519707_4	391625.PPSIR1_07420	2.593e-47	183.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	ybfF	-	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
WXD1_k127_6519707_2	861299.J421_3894	8.391e-167	537.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WXD1_k127_6519707_1	880073.Calab_0773	1.001e-245	775.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
WXD1_k127_6519707_0	861299.J421_5840	7.68e-291	926.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WXD1_k127_6519707_5	485918.Cpin_1461	3.068e-37	153.0	COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,1J06V@117747|Sphingobacteriia	976|Bacteroidetes	S	Starch-binding associating with outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SusD-like_2
WXD1_k127_6524012_0	861299.J421_2748	1.114e-286	891.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WXD1_k127_6524012_16	861299.J421_2753	6.924e-32	133.0	2E9HN@1|root,333QR@2|Bacteria,1ZTU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6524012_9	1379270.AUXF01000004_gene3061	2.778e-72	255.0	COG1842@1|root,COG1842@2|Bacteria,1ZT82@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
WXD1_k127_6524012_8	861299.J421_2755	1.526e-94	322.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WXD1_k127_6524012_10	504472.Slin_5441	9.759e-70	263.0	COG2866@1|root,COG2866@2|Bacteria,4NDXH@976|Bacteroidetes,47MSA@768503|Cytophagia	976|Bacteroidetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WXD1_k127_6524012_12	378806.STAUR_0277	5.673e-55	218.0	COG2367@1|root,COG2367@2|Bacteria,1Q2UC@1224|Proteobacteria,438GK@68525|delta/epsilon subdivisions,2X3RE@28221|Deltaproteobacteria,2YWXF@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
WXD1_k127_6524012_6	420246.GTNG_1290	2.556e-115	398.0	COG3876@1|root,COG3876@2|Bacteria,1VRMG@1239|Firmicutes,4HA8F@91061|Bacilli,1WFX8@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF1343)	ybbC	-	-	-	-	-	-	-	-	-	-	-	DUF1343
WXD1_k127_6524012_5	861299.J421_3604	7.549e-137	475.0	COG1472@1|root,COG1472@2|Bacteria,1ZTD2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
WXD1_k127_6524012_3	518766.Rmar_0925	9.813e-177	595.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
WXD1_k127_6524012_2	861299.J421_3607	4.22e-265	834.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,1ZSQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
WXD1_k127_6524012_4	1379270.AUXF01000003_gene3853	4.941e-151	492.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WXD1_k127_6524012_15	1210884.HG799463_gene9397	2.695e-33	144.0	COG2103@1|root,COG2971@1|root,COG2103@2|Bacteria,COG2971@2|Bacteria,2IWTZ@203682|Planctomycetes	203682|Planctomycetes	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
WXD1_k127_6524012_13	861299.J421_3610	3.066e-43	162.0	COG0662@1|root,COG0662@2|Bacteria,1ZTKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WXD1_k127_6524012_14	1430440.MGMSRv2_0461	2.049e-39	152.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,2JTRD@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
WXD1_k127_6524012_11	861299.J421_3830	9.286e-57	217.0	COG2856@1|root,COG2856@2|Bacteria,1ZSXU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6524012_1	379066.GAU_0720	9.042e-275	883.0	COG4206@1|root,COG4206@2|Bacteria,1ZUC2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug
WXD1_k127_6524012_7	861299.J421_1744	1.486e-111	380.0	2F03J@1|root,33T76@2|Bacteria,1ZUN0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Pfam:SusD	-	-	-	-	-	-	-	-	-	-	-	-	SusD_RagB
WXD1_k127_6524012_18	861299.J421_1746	1.251e-14	85.0	2CKIA@1|root,345C4@2|Bacteria,1ZV3S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
WXD1_k127_6526394_0	309807.SRU_0565	6.506e-108	356.0	COG1404@1|root,COG1404@2|Bacteria,4NF1M@976|Bacteroidetes,1FK0U@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	Subtilase family	wprA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
WXD1_k127_6526394_1	379066.GAU_3920	2.915e-79	286.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,1ZTYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
WXD1_k127_6526394_4	1396141.BATP01000026_gene1028	3.284e-16	87.0	COG0642@1|root,COG2205@2|Bacteria,46UCX@74201|Verrucomicrobia,2IV4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WXD1_k127_6526394_2	861299.J421_3015	4.699e-45	173.0	2DG4T@1|root,2ZUHN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6526394_3	1128421.JAGA01000002_gene252	1.961e-27	116.0	COG1950@1|root,COG1950@2|Bacteria	2|Bacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	yvlD	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
WXD1_k127_6529211_7	1379698.RBG1_1C00001G1850	1.817e-52	196.0	COG0705@1|root,COG0705@2|Bacteria,2NPSK@2323|unclassified Bacteria	2|Bacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WXD1_k127_6529211_5	1112217.PPL19_13920	9.222e-128	416.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008716,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iAF1260.b0381,iB21_1397.B21_00332,iBWG_1329.BWG_0265,iE2348C_1286.E2348C_0317,iEC042_1314.EC042_0413,iEC55989_1330.EC55989_0386,iECBD_1354.ECBD_3283,iECB_1328.ECB_00328,iECDH10B_1368.ECDH10B_0338,iECDH1ME8569_1439.ECDH1ME8569_0367,iECD_1391.ECD_00328,iECH74115_1262.ECH74115_0453,iECIAI1_1343.ECIAI1_0377,iECIAI39_1322.ECIAI39_0301,iECO103_1326.ECO103_0356,iECO111_1330.ECO111_0411,iECO26_1355.ECO26_0414,iECSE_1348.ECSE_0401,iECSP_1301.ECSP_0441,iECs_1301.ECs0431,iETEC_1333.ETEC_0434,iEcDH1_1363.EcDH1_3227,iEcE24377_1341.EcE24377A_0406,iEcHS_1320.EcHS_A0447,iEcSMS35_1347.EcSMS35_0410,iEcolC_1368.EcolC_3251,iJO1366.b0381,iJR904.b0381,iSF_1195.SF0232,iSFxv_1172.SFxv_0245,iS_1188.S0254,iUMNK88_1353.UMNK88_429,iY75_1357.Y75_RS01965,iZ_1308.Z0477	Dala_Dala_lig_C,Dala_Dala_lig_N
WXD1_k127_6529211_2	861299.J421_0897	7.967e-184	592.0	COG0031@1|root,COG0031@2|Bacteria,1ZTA6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EK	Domain in cystathionine beta-synthase and other proteins.	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
WXD1_k127_6529211_13	398578.Daci_5812	0.0001531	49.0	COG0810@1|root,COG0810@2|Bacteria,1NHEC@1224|Proteobacteria	1224|Proteobacteria	M	tonb protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WXD1_k127_6529211_1	518766.Rmar_1542	4.101e-249	798.0	COG0249@1|root,COG0249@2|Bacteria,4NEGB@976|Bacteroidetes,1FJ5H@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WXD1_k127_6529211_0	1379270.AUXF01000002_gene1728	1.405e-277	882.0	COG0567@1|root,COG0567@2|Bacteria,1ZSVR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoglutarate dehydrogenase N-terminus	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
WXD1_k127_6529211_11	1280948.HY36_04020	3.749e-17	82.0	2EGHT@1|root,33A9W@2|Bacteria,1NHZD@1224|Proteobacteria,2V70B@28211|Alphaproteobacteria,43YSN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6529211_6	330214.NIDE3500	6.627e-63	224.0	COG1704@1|root,COG1704@2|Bacteria	2|Bacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WXD1_k127_6529211_4	330214.NIDE3501	9.55e-137	459.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
WXD1_k127_6529211_10	861299.J421_0238	2.533e-18	93.0	2F3IF@1|root,33WC0@2|Bacteria,1ZTPE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6529211_9	861299.J421_1601	4.572e-20	99.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
WXD1_k127_6529211_3	765420.OSCT_1463	1.103e-180	574.0	COG0626@1|root,COG0626@2|Bacteria,2G7Q6@200795|Chloroflexi,3770M@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
WXD1_k127_6529211_12	1131269.AQVV01000001_gene1432	5.813e-05	55.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	ung2	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WXD1_k127_6529211_8	1379270.AUXF01000002_gene1281	2.567e-40	171.0	COG1629@1|root,COG4771@2|Bacteria,1ZU8C@142182|Gemmatimonadetes	2|Bacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WXD1_k127_6542927_5	1266998.ATUJ01000015_gene2216	7.276e-14	85.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2PUVF@265|Paracoccus	28211|Alphaproteobacteria	M	Peptidase family M23	MA20_30780	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WXD1_k127_6542927_4	639030.JHVA01000001_gene1570	1.427e-30	124.0	COG0720@1|root,COG0720@2|Bacteria,3Y4HE@57723|Acidobacteria,2JJ9Q@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM 6-pyruvoyl tetrahydropterin	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WXD1_k127_6542927_2	1379270.AUXF01000004_gene3096	1.906e-52	193.0	COG4221@1|root,COG4221@2|Bacteria,1ZTPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WXD1_k127_6542927_0	379066.GAU_0780	3.974e-76	262.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WXD1_k127_6542927_3	867900.Celly_0512	1.725e-46	173.0	COG0720@1|root,COG0720@2|Bacteria,4NNIS@976|Bacteroidetes,1I1ZF@117743|Flavobacteriia,1F9A2@104264|Cellulophaga	976|Bacteroidetes	H	TIGRFAM 6-pyruvoyl tetrahydropterin synthase QueD family protein	ygcM	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WXD1_k127_6542927_1	861299.J421_3762	5.768e-75	263.0	COG0648@1|root,COG0648@2|Bacteria,1ZSY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
WXD1_k127_6547875_2	867900.Celly_0996	6.672e-102	336.0	COG4805@1|root,COG4805@2|Bacteria,4NJ6P@976|Bacteroidetes	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6547875_0	29581.BW37_03897	2.409e-150	496.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2VP98@28216|Betaproteobacteria,473TB@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Winged helix DNA-binding domain	ycaQ	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
WXD1_k127_6547875_1	497964.CfE428DRAFT_0910	1.366e-128	428.0	COG1533@1|root,COG1533@2|Bacteria,46S99@74201|Verrucomicrobia	74201|Verrucomicrobia	L	SMART Elongator protein 3 MiaB NifB	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WXD1_k127_6547875_4	1379698.RBG1_1C00001G0468	1.257e-22	107.0	COG2318@1|root,COG2318@2|Bacteria,2NRQN@2323|unclassified Bacteria	2|Bacteria	S	DinB family	yrdA	-	-	-	-	-	-	-	-	-	-	-	DinB
WXD1_k127_6547875_3	880073.Calab_3409	5.055e-55	209.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	DUF4912,PBP_like_2
WXD1_k127_6560771_5	444157.Tneu_1020	0.0005692	43.0	COG0494@1|root,arCOG01078@2157|Archaea	2157|Archaea	L	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WXD1_k127_6560771_4	1120951.AUBG01000013_gene2673	4.337e-05	55.0	COG5183@1|root,COG5183@2|Bacteria,4NR0S@976|Bacteroidetes,1I34T@117743|Flavobacteriia	976|Bacteroidetes	A	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
WXD1_k127_6560771_0	1123388.AQWU01000073_gene1106	1.553e-34	141.0	COG2120@1|root,COG2120@2|Bacteria,1WIWN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	GlcNAc-PI de-N-acetylase	lmbE	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WXD1_k127_6560771_2	926550.CLDAP_25850	4.756e-09	66.0	2ERYI@1|root,33JHP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6560771_3	192952.MM_2246	3.094e-08	61.0	COG0640@1|root,arCOG01681@2157|Archaea,2XYSN@28890|Euryarchaeota,2NBKM@224756|Methanomicrobia	224756|Methanomicrobia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WXD1_k127_6560771_1	251221.35214297	8.215e-20	92.0	COG1301@1|root,COG1301@2|Bacteria,1G32C@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
WXD1_k127_6575418_0	1254432.SCE1572_50085	3.057e-84	289.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2YUA8@29|Myxococcales	28221|Deltaproteobacteria	J	glutaminyl-tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
WXD1_k127_6575418_2	1278073.MYSTI_01300	1.453e-34	151.0	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,43ADC@68525|delta/epsilon subdivisions,2X5T8@28221|Deltaproteobacteria,2Z38R@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	lytT	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
WXD1_k127_6575418_1	1121013.P873_12620	3.948e-42	166.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1X3UW@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
WXD1_k127_6577801_8	379066.GAU_2745	4.397e-08	59.0	2CA9X@1|root,2ZJY8@2|Bacteria,1ZU1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6577801_6	1232410.KI421421_gene3493	1.417e-16	84.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P5K@68525|delta/epsilon subdivisions,2WMEF@28221|Deltaproteobacteria,43TIX@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_6577801_7	861299.J421_2365	2.908e-12	73.0	2C181@1|root,34B2S@2|Bacteria,1ZU30@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_6577801_1	643648.Slip_0914	1.146e-52	194.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,42JZ5@68298|Syntrophomonadaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WXD1_k127_6577801_2	1382304.JNIL01000001_gene626	2.502e-46	169.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WXD1_k127_6577801_0	861299.J421_3824	7.033e-91	304.0	COG0336@1|root,COG0336@2|Bacteria,1ZT8K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WXD1_k127_6577801_4	1122611.KB903996_gene7423	4.18e-19	90.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4EJ2M@85012|Streptosporangiales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WXD1_k127_6577801_9	1123226.KB899277_gene1240	1.059e-07	57.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli,26TCR@186822|Paenibacillaceae	91061|Bacilli	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WXD1_k127_6577801_5	1111135.HMPREF1248_0693	6.304e-19	94.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CWB2@84998|Coriobacteriia	84998|Coriobacteriia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WXD1_k127_6577801_3	861299.J421_3827	5.278e-27	112.0	COG0541@1|root,COG0541@2|Bacteria,1ZSPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WXD1_k127_6627401_0	861299.J421_1629	0.0	1049.0	COG2866@1|root,COG2866@2|Bacteria,1ZSMP@142182|Gemmatimonadetes	2|Bacteria	E	Zinc carboxypeptidase	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
WXD1_k127_688986_0	861299.J421_4494	6.485e-46	169.0	COG3682@1|root,COG3682@2|Bacteria,1ZU4Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
WXD1_k127_688986_1	861299.J421_4535	4.239e-45	187.0	COG4219@1|root,COG4219@2|Bacteria,1ZUY4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,TonB_C
WXD1_k127_696782_3	946483.Cenrod_1211	2.861e-68	246.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4166,Sacchrp_dh_NADP
WXD1_k127_696782_5	861299.J421_2212	4.958e-60	212.0	COG0742@1|root,COG0742@2|Bacteria,1ZTNJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
WXD1_k127_696782_4	397945.Aave_0666	5.044e-68	237.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VR34@28216|Betaproteobacteria,4AA2R@80864|Comamonadaceae	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
WXD1_k127_696782_2	324925.Ppha_1822	1.098e-71	251.0	COG4912@1|root,COG4912@2|Bacteria,1FDUX@1090|Chlorobi	1090|Chlorobi	L	PFAM DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WXD1_k127_696782_7	1382305.AZUC01000047_gene757	2.202e-18	94.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli,26FTM@186818|Planococcaceae	91061|Bacilli	J	RNA-binding protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
WXD1_k127_696782_6	1254432.SCE1572_06430	4.332e-34	135.0	COG1293@1|root,COG1293@2|Bacteria	2|Bacteria	K	actin binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
WXD1_k127_696782_1	530564.Psta_2126	6.058e-129	425.0	COG0162@1|root,COG0162@2|Bacteria,2IXZM@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WXD1_k127_696782_0	1379270.AUXF01000002_gene1507	7.626e-140	465.0	COG1680@1|root,COG1680@2|Bacteria,1ZUDN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WXD1_k127_717426_2	1121918.ARWE01000001_gene3079	7.139e-24	106.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
WXD1_k127_717426_0	1121405.dsmv_1953	8.27e-143	468.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,2MJ3H@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WXD1_k127_717426_1	1125863.JAFN01000001_gene2833	4.799e-96	325.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WXD1_k127_736231_1	1379270.AUXF01000002_gene1120	6.554e-65	237.0	COG0705@1|root,COG0705@2|Bacteria,1ZSWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WXD1_k127_736231_2	398767.Glov_1846	2.406e-05	56.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,43SFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
WXD1_k127_736231_0	379066.GAU_3895	2.815e-110	366.0	COG1181@1|root,COG1181@2|Bacteria,1ZTFQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WXD1_k127_760885_2	861299.J421_1034	5.551e-62	219.0	COG1595@1|root,COG1595@2|Bacteria,1ZV2D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
WXD1_k127_760885_1	861299.J421_1729	3.17e-126	437.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WXD1_k127_760885_6	436229.JOEH01000011_gene5387	4.874e-21	110.0	COG0457@1|root,COG2909@1|root,COG4995@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,COG4995@2|Bacteria,2GKCX@201174|Actinobacteria	201174|Actinobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
WXD1_k127_760885_0	903818.KI912268_gene1318	3.339e-172	553.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
WXD1_k127_760885_3	452637.Oter_1107	3.017e-51	194.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WXD1_k127_760885_4	530564.Psta_4322	5.436e-41	169.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
WXD1_k127_760885_5	395965.Msil_0356	8.977e-26	111.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,3N9SN@45404|Beijerinckiaceae	28211|Alphaproteobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WXD1_k127_776667_4	1232410.KI421418_gene2328	1.548e-14	85.0	COG3170@1|root,COG3170@2|Bacteria,1QZ44@1224|Proteobacteria,43CF0@68525|delta/epsilon subdivisions,2X7PZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
WXD1_k127_776667_2	1191523.MROS_0295	1.168e-45	181.0	COG1086@1|root,COG1216@1|root,COG2148@1|root,COG1086@2|Bacteria,COG1216@2|Bacteria,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	wbbL	-	-	ko:K03606,ko:K07011	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
WXD1_k127_776667_0	1430331.EP10_02975	4.944e-68	248.0	COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HEKI@91061|Bacilli,1WH7Z@129337|Geobacillus	91061|Bacilli	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt,Polysacc_synt_C
WXD1_k127_776667_3	479434.Sthe_3448	2.478e-21	108.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WXD1_k127_776667_1	56110.Oscil6304_2653	1.244e-46	190.0	COG0438@1|root,COG0438@2|Bacteria,1G8JK@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WXD1_k127_795320_0	472759.Nhal_2659	2.789e-55	196.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,1RQ15@1236|Gammaproteobacteria,1X0JQ@135613|Chromatiales	135613|Chromatiales	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_795320_1	1123389.ATXJ01000001_gene872	3.143e-23	111.0	COG1051@1|root,COG1051@2|Bacteria,1WJX0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WXD1_k127_795320_2	1499967.BAYZ01000172_gene5765	1.084e-22	108.0	COG3695@1|root,COG3695@2|Bacteria,2NRVD@2323|unclassified Bacteria	2|Bacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	2.1.1.63	ko:K00567,ko:K07443	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
WXD1_k127_795320_3	518766.Rmar_0596	1.312e-17	86.0	COG0301@1|root,COG0607@1|root,COG0301@2|Bacteria,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	iECNA114_1301.ECNA114_0400,iECO26_1355.ECO26_0455,iECSF_1327.ECSF_0383,iSDY_1059.SDY_0307	THUMP,ThiI
WXD1_k127_796675_10	861299.J421_6332	1.857e-20	95.0	COG1680@1|root,COG1680@2|Bacteria,1ZTCC@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	nagA	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
WXD1_k127_796675_3	661478.OP10G_3097	2.46e-105	363.0	COG2833@1|root,COG2833@2|Bacteria	2|Bacteria	I	Protein of unknown function (DUF455)	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF455
WXD1_k127_796675_5	383372.Rcas_2639	1.513e-49	194.0	COG0642@1|root,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS_4
WXD1_k127_796675_11	1121918.ARWE01000001_gene3028	3.263e-12	79.0	COG2199@1|root,COG3850@1|root,COG3706@2|Bacteria,COG3850@2|Bacteria,1N9PI@1224|Proteobacteria,42MQF@68525|delta/epsilon subdivisions,2WIUE@28221|Deltaproteobacteria,43U1U@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
WXD1_k127_796675_4	717606.PaecuDRAFT_2099	2.654e-88	308.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,4HAPK@91061|Bacilli,26V88@186822|Paenibacillaceae	91061|Bacilli	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
WXD1_k127_796675_0	1096546.WYO_3457	1.113e-214	681.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,1JS3J@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0061 (SELO) family	MA20_28420	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
WXD1_k127_796675_2	1379270.AUXF01000002_gene1559	4.001e-151	486.0	COG3832@1|root,COG3832@2|Bacteria,1ZUBY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WXD1_k127_796675_6	1379270.AUXF01000002_gene1560	9.191e-43	162.0	COG0640@1|root,COG0640@2|Bacteria,1ZV15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
WXD1_k127_796675_1	29581.BW37_02621	2.066e-188	602.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,473IT@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
WXD1_k127_796675_7	945713.IALB_2100	8.896e-39	150.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
WXD1_k127_796675_8	234267.Acid_5630	1.809e-25	117.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WXD1_k127_796675_9	1122612.AUBA01000004_gene492	5.115e-23	106.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,2K64K@204457|Sphingomonadales	204457|Sphingomonadales	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
WXD1_k127_796675_12	986075.CathTA2_1618	1.125e-11	66.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli	91061|Bacilli	F	gtp cyclohydrolase	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WXD1_k127_798874_14	1449050.JNLE01000003_gene401	3.2e-06	51.0	2EFGV@1|root,3399G@2|Bacteria,1VHIS@1239|Firmicutes,24SXP@186801|Clostridia,36P84@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_798874_16	1197906.CAJQ02000003_gene3219	4.781e-05	50.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WXD1_k127_798874_13	1461580.CCAS010000118_gene4580	2.125e-06	55.0	2DDW9@1|root,2ZJJ8@2|Bacteria,1W4EI@1239|Firmicutes,4I1RT@91061|Bacilli,1ZK7C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_798874_0	861299.J421_2423	0.0	1120.0	COG0495@1|root,COG0495@2|Bacteria,1ZSXC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WXD1_k127_798874_3	1379270.AUXF01000004_gene3140	4.807e-72	273.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
WXD1_k127_798874_4	861299.J421_5622	1.847e-67	264.0	COG0642@1|root,COG2205@2|Bacteria	861299.J421_5622|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_798874_7	1128421.JAGA01000001_gene2006	7.911e-34	141.0	COG2363@1|root,COG2363@2|Bacteria,2NRMS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
WXD1_k127_798874_6	880074.BARVI_08660	3.822e-50	204.0	COG3392@1|root,COG3392@2|Bacteria,4NJNW@976|Bacteroidetes,2FRYH@200643|Bacteroidia,22YFJ@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
WXD1_k127_798874_5	1242864.D187_006584	1.903e-62	231.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria	1224|Proteobacteria	I	COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WXD1_k127_798874_2	861299.J421_2641	2.367e-80	299.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
WXD1_k127_798874_9	926566.Terro_0874	4.25e-17	83.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
WXD1_k127_798874_1	1303518.CCALI_00532	6.14e-151	503.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
WXD1_k127_798874_8	710111.FraQA3DRAFT_3000	3.4e-19	102.0	COG5360@1|root,COG5360@2|Bacteria,2IRU3@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Heparinase II	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
WXD1_k127_798874_10	443143.GM18_1655	5.215e-09	69.0	COG0438@1|root,COG0438@2|Bacteria,1RKHV@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
WXD1_k127_800848_2	306281.AJLK01000084_gene1615	1.029e-71	248.0	COG2366@1|root,COG2366@2|Bacteria,1G0QT@1117|Cyanobacteria,1JK3D@1189|Stigonemataceae	1117|Cyanobacteria	S	Penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WXD1_k127_800848_3	278963.ATWD01000001_gene1983	2.837e-40	165.0	COG2095@1|root,COG2095@2|Bacteria,3Y429@57723|Acidobacteria,2JI6F@204432|Acidobacteriia	204432|Acidobacteriia	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
WXD1_k127_800848_4	1121937.AUHJ01000003_gene3208	1.057e-28	124.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S9VR@1236|Gammaproteobacteria,4686G@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WXD1_k127_800848_0	880072.Desac_2444	4.019e-193	622.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria,2MQ7P@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WXD1_k127_800848_1	1183438.GKIL_4428	2.346e-104	353.0	COG0618@1|root,COG0618@2|Bacteria,1G12Y@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH
WXD1_k127_800848_5	379066.GAU_2585	3.392e-16	84.0	2C9AX@1|root,33WUH@2|Bacteria,1ZTQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_810908_1	338969.Rfer_4073	1.461e-61	222.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_810908_2	452637.Oter_2603	2.498e-48	189.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
WXD1_k127_810908_0	1121918.ARWE01000001_gene445	3.67e-104	367.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WXD1_k127_810908_3	243231.GSU2916	4.015e-43	176.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42TFH@68525|delta/epsilon subdivisions,2WPEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WXD1_k127_830169_36	1125863.JAFN01000001_gene1407	1.804e-26	113.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WXD1_k127_830169_0	1125863.JAFN01000001_gene2410	8.855e-192	620.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
WXD1_k127_830169_35	1232410.KI421424_gene1791	9.476e-28	119.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,43V3G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
WXD1_k127_830169_34	1379270.AUXF01000006_gene238	1.717e-31	133.0	COG0839@1|root,COG0839@2|Bacteria,1ZTSA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WXD1_k127_830169_19	1379270.AUXF01000006_gene237	1.597e-73	271.0	COG1143@1|root,COG1143@2|Bacteria,1ZTHB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
WXD1_k127_830169_8	379066.GAU_1655	3.171e-137	450.0	COG1005@1|root,COG1005@2|Bacteria,1ZTDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WXD1_k127_830169_6	861299.J421_3289	5.082e-142	483.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1ZTDW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
WXD1_k127_830169_2	379066.GAU_1657	3.706e-171	546.0	COG1894@1|root,COG1894@2|Bacteria,1ZSQD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WXD1_k127_830169_26	379066.GAU_1658	1.254e-54	199.0	COG1905@1|root,COG1905@2|Bacteria,1ZTJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WXD1_k127_830169_1	861299.J421_3292	7.467e-176	562.0	COG0649@1|root,COG0649@2|Bacteria,1ZSV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
WXD1_k127_830169_28	861299.J421_3293	1.234e-46	178.0	COG0852@1|root,COG0852@2|Bacteria,1ZTCJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
WXD1_k127_830169_16	1379270.AUXF01000006_gene230	2.196e-77	271.0	COG0377@1|root,COG0377@2|Bacteria,1ZT85@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
WXD1_k127_830169_30	379066.GAU_1662	1.407e-41	158.0	COG0838@1|root,COG0838@2|Bacteria,1ZTKK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WXD1_k127_830169_14	316274.Haur_1314	1.232e-87	292.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi,37574@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
WXD1_k127_830169_21	1121430.JMLG01000037_gene142	5.576e-65	240.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WXD1_k127_830169_33	742738.HMPREF9460_00400	2.257e-32	143.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,2685H@186813|unclassified Clostridiales	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
WXD1_k127_830169_17	926560.KE387023_gene3851	6.777e-75	264.0	COG0157@1|root,COG0157@2|Bacteria,1WIHZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
WXD1_k127_830169_9	379066.GAU_1532	1.224e-127	421.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,1ZT2W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase 4-like	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WXD1_k127_830169_24	1125863.JAFN01000001_gene1885	1.295e-61	224.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WXD1_k127_830169_3	1379270.AUXF01000005_gene784	7.906e-164	534.0	COG0323@1|root,COG0323@2|Bacteria,1ZT6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WXD1_k127_830169_23	562970.Btus_0052	7.885e-62	223.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,27859@186823|Alicyclobacillaceae	91061|Bacilli	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WXD1_k127_830169_20	1232410.KI421418_gene2299	1.556e-65	235.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43RZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	SecD/SecF GG Motif	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WXD1_k127_830169_10	1379270.AUXF01000005_gene826	6.214e-118	401.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WXD1_k127_830169_13	1379270.AUXF01000002_gene1182	9.554e-97	322.0	COG0035@1|root,COG0035@2|Bacteria,1ZT1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
WXD1_k127_830169_31	861299.J421_3154	1.743e-40	172.0	COG4783@1|root,COG4783@2|Bacteria,1ZT36@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD,SH3_4
WXD1_k127_830169_18	861299.J421_3153	1.185e-73	279.0	COG2304@1|root,COG2304@2|Bacteria,1ZTCZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
WXD1_k127_830169_11	379066.GAU_1527	1.319e-103	349.0	COG2304@1|root,COG2304@2|Bacteria,1ZSVY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF1194)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
WXD1_k127_830169_38	1107311.Q767_08270	1.906e-10	74.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,1HY3G@117743|Flavobacteriia,2NSJZ@237|Flavobacterium	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_830169_12	1379270.AUXF01000005_gene779	6.32e-99	337.0	COG1721@1|root,COG1721@2|Bacteria,1ZSKR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WXD1_k127_830169_7	861299.J421_3150	4.016e-138	446.0	COG0714@1|root,COG0714@2|Bacteria,1ZT94@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WXD1_k127_830169_5	869210.Marky_1233	1.734e-149	491.0	COG1086@1|root,COG1086@2|Bacteria	2|Bacteria	GM	Polysaccharide biosynthesis protein	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf,CoA_binding_3,Glycos_transf_4,HTH_45,LicD
WXD1_k127_830169_22	767029.HMPREF9154_2003	2.844e-63	224.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,4DNT7@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WXD1_k127_830169_27	861299.J421_3148	7.153e-48	184.0	COG1386@1|root,COG1386@2|Bacteria,1ZTIA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WXD1_k127_830169_32	76869.PputGB1_4004	3.203e-34	147.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1YXP7@136845|Pseudomonas putida group	1236|Gammaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WXD1_k127_830169_29	589865.DaAHT2_0739	4.645e-43	165.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,2MKSG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
WXD1_k127_830169_37	1123236.KB899379_gene1363	1.082e-10	65.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,467QN@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WXD1_k127_830169_25	1121918.ARWE01000001_gene1221	2.291e-59	226.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,43T29@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
WXD1_k127_830169_4	861299.J421_3143	7.886e-161	519.0	COG0044@1|root,COG0044@2|Bacteria,1ZT4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WXD1_k127_830169_15	1379270.AUXF01000005_gene770	6.03e-81	271.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WXD1_k127_833262_10	379066.GAU_0431	6.119e-53	194.0	COG5276@1|root,COG5276@2|Bacteria,1ZUNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WXD1_k127_833262_6	861299.J421_2036	7.423e-91	317.0	2EXQQ@1|root,33R07@2|Bacteria,1ZUK8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_833262_0	861299.J421_3034	2.401e-134	451.0	COG0465@1|root,COG0465@2|Bacteria,1ZSRI@142182|Gemmatimonadetes	2|Bacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WXD1_k127_833262_21	7668.SPU_011423-tr	1.877e-06	58.0	KOG3854@1|root,KOG3854@2759|Eukaryota,39RR1@33154|Opisthokonta,3BGBE@33208|Metazoa,3CSN1@33213|Bilateria	33208|Metazoa	O	Acidic repeat-containing protein	ACRC	GO:0000003,GO:0000280,GO:0000793,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006304,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0022402,GO:0022414,GO:0034641,GO:0035510,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044728,GO:0045132,GO:0046483,GO:0048285,GO:0051321,GO:0070988,GO:0071704,GO:0071840,GO:0080111,GO:0090304,GO:0098813,GO:0140013,GO:1901360,GO:1903046	-	-	-	-	-	-	-	-	-	-	SprT-like,Zn_ribbon_SprT
WXD1_k127_833262_8	861299.J421_0308	6.226e-71	249.0	COG1595@1|root,COG1595@2|Bacteria,1ZTP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_833262_7	861299.J421_0306	3.267e-86	306.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WXD1_k127_833262_15	861299.J421_0305	2.458e-31	134.0	COG1413@1|root,COG1413@2|Bacteria,1ZTU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WXD1_k127_833262_1	518766.Rmar_1907	5.255e-133	441.0	COG2866@1|root,COG2866@2|Bacteria,4NF5T@976|Bacteroidetes	976|Bacteroidetes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WXD1_k127_833262_9	323848.Nmul_A2110	4.848e-60	209.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,373GQ@32003|Nitrosomonadales	28216|Betaproteobacteria	C	SelR domain	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	SelR
WXD1_k127_833262_5	1382306.JNIM01000001_gene876	3.845e-95	321.0	COG0384@1|root,COG0384@2|Bacteria,2G7RE@200795|Chloroflexi	200795|Chloroflexi	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
WXD1_k127_833262_12	1123256.KB907944_gene421	2.668e-45	173.0	COG1595@1|root,COG1595@2|Bacteria,1RI1M@1224|Proteobacteria,1S780@1236|Gammaproteobacteria,1X678@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WXD1_k127_833262_20	861299.J421_4376	1.018e-12	78.0	2F756@1|root,33ZKP@2|Bacteria,1ZU38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_833262_17	1500893.JQNB01000001_gene1615	1.377e-21	106.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WXD1_k127_833262_13	1379270.AUXF01000001_gene2631	1.173e-43	170.0	COG3595@1|root,COG3595@2|Bacteria,1ZTQ0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WXD1_k127_833262_14	1379270.AUXF01000004_gene2925	6.242e-38	147.0	COG1846@1|root,COG1846@2|Bacteria,1ZU3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
WXD1_k127_833262_18	1166948.JPZL01000002_gene1602	6.548e-14	85.0	COG1073@1|root,COG1073@2|Bacteria,1RM16@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
WXD1_k127_833262_11	526227.Mesil_0199	1.004e-50	190.0	COG0596@1|root,COG0596@2|Bacteria,1WJF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WXD1_k127_833262_19	861299.J421_4201	2.995e-13	73.0	2CA00@1|root,344QM@2|Bacteria,1ZU1Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_833262_4	479434.Sthe_1848	4.084e-103	351.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi,27YYU@189775|Thermomicrobia	189775|Thermomicrobia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WXD1_k127_833262_3	1297742.A176_00264	8.755e-106	361.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2Z2X4@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
WXD1_k127_833262_2	861299.J421_3395	2.437e-127	430.0	COG0768@1|root,COG0768@2|Bacteria,1ZSX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WXD1_k127_833262_22	379066.GAU_2601	0.0002622	49.0	2FK78@1|root,34BUZ@2|Bacteria,1ZU15@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_833625_2	443143.GM18_1644	2.523e-28	124.0	COG0399@1|root,COG0399@2|Bacteria,1PDU2@1224|Proteobacteria,42RZB@68525|delta/epsilon subdivisions,2WNIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WXD1_k127_833625_1	1379270.AUXF01000004_gene3328	2.617e-74	264.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WXD1_k127_833625_0	1279019.ARQK01000059_gene894	1.76e-86	297.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,1RREJ@1236|Gammaproteobacteria,1WWEV@135613|Chromatiales	135613|Chromatiales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
WXD1_k127_833625_4	1389489.O159_08380	1.567e-06	60.0	COG4767@1|root,COG4767@2|Bacteria,2ISME@201174|Actinobacteria,4FPXT@85023|Microbacteriaceae	201174|Actinobacteria	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WXD1_k127_833625_3	1158756.AQXQ01000011_gene718	8.534e-13	76.0	COG0394@1|root,COG3919@1|root,COG0394@2|Bacteria,COG3919@2|Bacteria,1R94Z@1224|Proteobacteria,1RQ74@1236|Gammaproteobacteria,1WZV0@135613|Chromatiales	135613|Chromatiales	T	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
WXD1_k127_834259_0	365046.Rta_31160	6.456e-211	666.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,4AB70@80864|Comamonadaceae	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WXD1_k127_834259_7	649638.Trad_1763	2.99e-12	77.0	COG5652@1|root,COG5652@2|Bacteria,1WK8S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM VanZ like	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WXD1_k127_834259_6	1209989.TepiRe1_2776	5.071e-29	123.0	COG1762@1|root,COG1762@2|Bacteria,1VA2N@1239|Firmicutes,24N94@186801|Clostridia,42GT5@68295|Thermoanaerobacterales	186801|Clostridia	G	TIGRFAM PTS system, fructose subfamily, IIA subunit	-	-	2.7.1.202	ko:K02768,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
WXD1_k127_834259_2	479434.Sthe_1821	1.115e-83	303.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi,27XRH@189775|Thermomicrobia	189775|Thermomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
WXD1_k127_834259_8	697303.Thewi_0029	1.709e-07	61.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,42FZZ@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM Cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WXD1_k127_834259_4	1379270.AUXF01000006_gene171	2.25e-34	140.0	COG1713@1|root,COG1713@2|Bacteria,1ZTTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	HD superfamily hydrolase involved in NAD metabolism	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	-
WXD1_k127_834259_5	858215.Thexy_1921	2.449e-33	142.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,42GKF@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
WXD1_k127_834259_3	644966.Tmar_0374	3.01e-78	282.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,3WCYN@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
WXD1_k127_834259_1	1519464.HY22_10935	4.738e-89	302.0	COG0413@1|root,COG0413@2|Bacteria,1FDQ8@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
WXD1_k127_835152_1	710111.FraQA3DRAFT_4770	9.985e-204	645.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4ESB0@85013|Frankiales	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WXD1_k127_835152_10	886293.Sinac_3668	4.862e-82	293.0	COG0534@1|root,COG0534@2|Bacteria,2IX5Q@203682|Planctomycetes	203682|Planctomycetes	V	COG0534 Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WXD1_k127_835152_7	1379270.AUXF01000003_gene3830	2.313e-104	356.0	COG2268@1|root,COG2268@2|Bacteria,1ZU4D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
WXD1_k127_835152_12	861299.J421_4361	4.802e-63	241.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WXD1_k127_835152_5	479434.Sthe_3153	4.419e-121	414.0	COG1108@1|root,COG1108@2|Bacteria,2G7XS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K11709	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
WXD1_k127_835152_3	1089550.ATTH01000001_gene2469	9.359e-122	403.0	COG1108@1|root,COG1108@2|Bacteria,4NH3D@976|Bacteroidetes,1FJRA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	ABC 3 transport family	mntC	-	-	ko:K11708	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3,Fe_dep_repr_C
WXD1_k127_835152_4	383372.Rcas_1723	1.1e-121	396.0	COG1121@1|root,COG1121@2|Bacteria,2G5WQ@200795|Chloroflexi,374U1@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K11710	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
WXD1_k127_835152_6	479434.Sthe_3156	1.298e-109	363.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,27XHP@189775|Thermomicrobia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09818,ko:K11707	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
WXD1_k127_835152_2	861299.J421_0343	1.18e-145	503.0	COG4206@1|root,COG4206@2|Bacteria,1ZSN0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
WXD1_k127_835152_0	644966.Tmar_0901	7.485e-216	692.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
WXD1_k127_835152_8	330214.NIDE1215	1.506e-97	329.0	COG0407@1|root,COG0407@2|Bacteria,3J0C3@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WXD1_k127_835152_11	1089550.ATTH01000001_gene660	1.75e-66	245.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1FIVK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WXD1_k127_835152_13	1121468.AUBR01000024_gene3020	6.546e-56	214.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,42EUS@68295|Thermoanaerobacterales	186801|Clostridia	H	extracellular solute-binding protein, family 1	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WXD1_k127_835152_9	1120973.AQXL01000071_gene680	3.698e-95	315.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,2781X@186823|Alicyclobacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WXD1_k127_835152_18	1333998.M2A_2398	4.39e-12	76.0	COG3409@1|root,COG3409@2|Bacteria,1NP3I@1224|Proteobacteria,2UM8V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_835152_15	631454.N177_1313	5.559e-27	117.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,1JPAA@119043|Rhodobiaceae	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WXD1_k127_835152_16	1123500.ATUU01000001_gene365	3.241e-22	101.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,4HNJC@91061|Bacilli,4AY21@81850|Leuconostocaceae	91061|Bacilli	K	COG1278 Cold shock proteins	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WXD1_k127_835152_14	861299.J421_6280	2.86e-31	130.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1ZV9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WXD1_k127_837758_0	379066.GAU_0007	2.675e-53	195.0	COG0461@1|root,COG0461@2|Bacteria,1ZTMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
WXD1_k127_837758_1	756499.Desde_1908	1.037e-19	97.0	COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V3CX@1239|Firmicutes,24IC2@186801|Clostridia,261SK@186807|Peptococcaceae	186801|Clostridia	C	PFAM Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WXD1_k127_859722_0	663932.KB902575_gene405	6.147e-77	268.0	COG1351@1|root,COG1351@2|Bacteria,1MWY8@1224|Proteobacteria,2TTER@28211|Alphaproteobacteria,2JQGP@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
WXD1_k127_859722_1	1089550.ATTH01000001_gene1367	2.228e-60	223.0	COG0697@1|root,COG0697@2|Bacteria,4NDYH@976|Bacteroidetes,1FK0X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EG	EamA-like transporter family	sam	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
WXD1_k127_859722_2	1379270.AUXF01000003_gene3431	8.39e-20	96.0	COG0308@1|root,COG0308@2|Bacteria,1ZUT0@142182|Gemmatimonadetes	2|Bacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WXD1_k127_862150_10	338969.Rfer_1930	4.342e-05	49.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,4AAKI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
WXD1_k127_862150_8	314345.SPV1_10249	1.149e-20	100.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria	1224|Proteobacteria	P	biogenesis protein	braZ	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
WXD1_k127_862150_5	861299.J421_4544	4.117e-53	201.0	COG0697@1|root,COG0697@2|Bacteria,1ZTM7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WXD1_k127_862150_6	479434.Sthe_2734	2.675e-40	156.0	COG5516@1|root,COG5516@2|Bacteria,2G7GV@200795|Chloroflexi	200795|Chloroflexi	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
WXD1_k127_862150_0	1123368.AUIS01000024_gene950	2.745e-121	413.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1SYDD@1236|Gammaproteobacteria,2NCJF@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WXD1_k127_862150_2	1123368.AUIS01000024_gene949	9.721e-113	392.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2NBU9@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WXD1_k127_862150_1	1123368.AUIS01000024_gene948	8.171e-115	383.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2NCCI@225057|Acidithiobacillales	225057|Acidithiobacillales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WXD1_k127_862150_3	1123368.AUIS01000024_gene947	7.163e-112	374.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2NDPN@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WXD1_k127_862150_4	1123368.AUIS01000024_gene946	2.792e-87	299.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RS3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Secretion protein	yhiI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WXD1_k127_862150_7	1163617.SCD_n01438	4.927e-21	108.0	COG1538@1|root,COG1538@2|Bacteria,1R4EG@1224|Proteobacteria,2VXKM@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WXD1_k127_862150_9	765913.ThidrDRAFT_4525	2.079e-07	59.0	COG1309@1|root,COG1309@2|Bacteria,1PE6J@1224|Proteobacteria,1TAD2@1236|Gammaproteobacteria,1WZQ8@135613|Chromatiales	135613|Chromatiales	K	regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
WXD1_k127_876177_5	1158292.JPOE01000002_gene1436	6.237e-07	60.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WXD1_k127_876177_4	880073.Calab_2425	6.467e-14	77.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WXD1_k127_876177_3	880073.Calab_2425	1.76e-21	99.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WXD1_k127_876177_2	1191523.MROS_2571	4.039e-38	153.0	COG0811@1|root,COG0811@2|Bacteria	2|Bacteria	U	bacteriocin transport	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
WXD1_k127_876177_1	861299.J421_3044	8.406e-65	236.0	COG1624@1|root,COG1624@2|Bacteria,1ZUI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
WXD1_k127_876177_0	404589.Anae109_2337	4.605e-69	242.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WXD1_k127_883762_0	861299.J421_3930	5.39e-93	317.0	COG2025@1|root,COG2025@2|Bacteria,1ZTDU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WXD1_k127_883762_1	1379270.AUXF01000003_gene3456	1.438e-67	242.0	COG2086@1|root,COG2086@2|Bacteria,1ZT51@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WXD1_k127_883762_3	365528.KB891250_gene5829	2.768e-49	191.0	COG0515@1|root,COG3391@1|root,COG0515@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,NHL,Pkinase
WXD1_k127_883762_4	309801.trd_0931	4.434e-08	65.0	COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,27XTF@189775|Thermomicrobia	189775|Thermomicrobia	U	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WXD1_k127_883762_2	518766.Rmar_0355	8.825e-50	203.0	COG1629@1|root,COG4771@2|Bacteria,4NTQD@976|Bacteroidetes	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WXD1_k127_899296_1	290397.Adeh_0975	1.262e-110	377.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MFH@68525|delta/epsilon subdivisions,2WIRW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
WXD1_k127_899296_2	404589.Anae109_1706	2.146e-67	240.0	COG0702@1|root,COG0702@2|Bacteria,1Q3VX@1224|Proteobacteria,439PX@68525|delta/epsilon subdivisions,2X51S@28221|Deltaproteobacteria,2YZZS@29|Myxococcales	28221|Deltaproteobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WXD1_k127_899296_4	195105.CN97_14150	1.177e-34	141.0	COG1853@1|root,COG1853@2|Bacteria,1MXPE@1224|Proteobacteria,2TS7H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WXD1_k127_899296_3	861299.J421_1222	3.279e-45	168.0	COG1393@1|root,COG1393@2|Bacteria,1ZTUV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
WXD1_k127_899296_0	1121920.AUAU01000004_gene751	5.535e-115	387.0	COG1748@1|root,COG1748@2|Bacteria,3Y84N@57723|Acidobacteria	57723|Acidobacteria	E	Saccharopine dehydrogenase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
WXD1_k127_902905_4	1128421.JAGA01000003_gene2970	7.779e-81	275.0	COG0498@1|root,COG0498@2|Bacteria,2NP4T@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0546,iSB619.SA_RS06615,iYO844.BSU32250	PALP
WXD1_k127_902905_3	861299.J421_4544	3.548e-86	299.0	COG0697@1|root,COG0697@2|Bacteria,1ZTM7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WXD1_k127_902905_1	518766.Rmar_2129	4.965e-201	639.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1FIWI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WXD1_k127_902905_2	1192034.CAP_4260	1.687e-91	312.0	COG1319@1|root,COG1319@2|Bacteria,1PG5C@1224|Proteobacteria,43EJH@68525|delta/epsilon subdivisions,2X9UI@28221|Deltaproteobacteria,2Z2GS@29|Myxococcales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
WXD1_k127_902905_5	861299.J421_0693	9.847e-68	237.0	COG0778@1|root,COG0778@2|Bacteria,1ZTKQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WXD1_k127_902905_8	713587.THITH_05005	1.935e-11	76.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,DUF5011,Gram_pos_anchor,SdrD_B
WXD1_k127_902905_7	309801.trd_1920	7.013e-25	118.0	COG5624@1|root,COG5624@2|Bacteria,2G94N@200795|Chloroflexi	200795|Chloroflexi	K	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_902905_0	391625.PPSIR1_18075	4.433e-320	1004.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WXD1_k127_902905_6	1382306.JNIM01000001_gene1022	5.083e-45	165.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WXD1_k127_919180_0	1121033.AUCF01000005_gene5299	1.945e-252	791.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,2U38G@28211|Alphaproteobacteria,2JRNY@204441|Rhodospirillales	204441|Rhodospirillales	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
WXD1_k127_919180_3	1121943.KB899992_gene2159	1.733e-69	244.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
WXD1_k127_919180_2	1121943.KB899992_gene2160	1.611e-87	301.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku,Rho_N
WXD1_k127_919180_1	518766.Rmar_1178	1.507e-218	704.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1FJT8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
WXD1_k127_941453_0	1499967.BAYZ01000048_gene2719	7.716e-44	181.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
WXD1_k127_941453_2	1227453.C444_08905	5.143e-16	92.0	COG0784@1|root,arCOG02333@2157|Archaea,2XVG6@28890|Euryarchaeota,23UBP@183963|Halobacteria	183963|Halobacteria	T	PAS PAC sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
WXD1_k127_941453_1	391615.ABSJ01000055_gene1359	9.73e-24	105.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator, receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WXD1_k127_961208_0	1415754.JQMK01000010_gene1335	3.651e-195	647.0	COG0419@1|root,COG0419@2|Bacteria,1QZI1@1224|Proteobacteria	1224|Proteobacteria	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_961208_1	313589.JNB_12758	1.538e-50	187.0	2CIEF@1|root,340EH@2|Bacteria,2GZN5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_961208_2	665942.HMPREF1022_01370	7.003e-27	127.0	2AYVU@1|root,31R1C@2|Bacteria,1QNK9@1224|Proteobacteria,436QC@68525|delta/epsilon subdivisions,2X1CP@28221|Deltaproteobacteria,2MESI@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_96450_4	1121015.N789_04820	1.727e-24	111.0	COG0406@1|root,COG0406@2|Bacteria,1N92W@1224|Proteobacteria,1SCJF@1236|Gammaproteobacteria,1X7ZV@135614|Xanthomonadales	135614|Xanthomonadales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WXD1_k127_96450_0	1379698.RBG1_1C00001G0629	7.191e-223	706.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	etf	GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8,Thi4
WXD1_k127_96450_1	861299.J421_3927	8.076e-102	353.0	COG0303@1|root,COG0303@2|Bacteria,1ZT4D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WXD1_k127_96450_2	861299.J421_5587	9.152e-36	152.0	COG0746@1|root,COG0746@2|Bacteria,1ZU64@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WXD1_k127_96450_5	1385511.N783_20045	1.04e-16	91.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,2Y9E5@289201|Pontibacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
WXD1_k127_96450_3	861299.J421_1645	1.651e-27	117.0	2A4CF@1|root,30SY3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
WXD1_k127_978897_4	693986.MOC_3574	1.245e-11	66.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2TQT2@28211|Alphaproteobacteria,1JXBE@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
WXD1_k127_978897_1	1379270.AUXF01000002_gene1787	2.142e-108	361.0	COG0726@1|root,COG0726@2|Bacteria,1ZSTP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WXD1_k127_978897_3	530564.Psta_0826	2.125e-53	192.0	COG3685@1|root,COG3685@2|Bacteria,2IZPC@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF892
WXD1_k127_978897_5	264732.Moth_2104	9.517e-06	57.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1V9ZW@1239|Firmicutes,25AZU@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	spr	-	-	ko:K19224,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
WXD1_k127_978897_2	861299.J421_3015	4.38e-55	204.0	2DG4T@1|root,2ZUHN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WXD1_k127_978897_0	926549.KI421517_gene511	1.613e-132	442.0	COG0477@1|root,COG2814@2|Bacteria,4NFRE@976|Bacteroidetes,47N91@768503|Cytophagia	976|Bacteroidetes	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WXD1_k127_978897_6	388467.A19Y_2101	1.121e-05	57.0	COG0457@1|root,COG1216@1|root,COG0457@2|Bacteria,COG1216@2|Bacteria,1GQBE@1117|Cyanobacteria,1H7DT@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,RgpF,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
WXD1_k127_995458_2	880073.Calab_1134	9.357e-134	447.0	COG2091@1|root,COG2091@2|Bacteria,2NQGR@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WXD1_k127_995458_4	1469607.KK073768_gene1825	5.781e-58	209.0	COG1896@1|root,COG1896@2|Bacteria,1G50J@1117|Cyanobacteria,1HK1Z@1161|Nostocales	1117|Cyanobacteria	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
WXD1_k127_995458_6	861299.J421_2070	5.31e-41	155.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
WXD1_k127_995458_0	861299.J421_1864	1.683e-206	662.0	COG0038@1|root,COG0038@2|Bacteria	2|Bacteria	P	chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
WXD1_k127_995458_3	748247.AZKH_2969	2.982e-79	273.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,2VJ9S@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WXD1_k127_995458_5	1297865.APJD01000015_gene3469	1.307e-50	204.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
WXD1_k127_995458_1	404589.Anae109_0939	1.859e-183	587.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
## 3279 queries scanned
## Total time (seconds): 10.583601236343384
## Rate: 309.82 q/s