## Fri Feb 20 01:18:24 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/WZS1_bin.10.fa -m mmseqs --output WZS1_bin.10 --output_dir /data/result/bins/wyx/eggqs50+/WZS1_bin.10 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WZS1_k127_1006128_3	379066.GAU_2359	1.802e-30	121.0	COG0745@1|root,COG0745@2|Bacteria,1ZTC6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS1_k127_1006128_1	379066.GAU_2360	1.365e-102	357.0	COG5002@1|root,COG5002@2|Bacteria,1ZT2H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WZS1_k127_1006128_0	867903.ThesuDRAFT_01219	3.362e-112	373.0	COG0226@1|root,COG0226@2|Bacteria,1UFGH@1239|Firmicutes,24D85@186801|Clostridia,3WDS1@538999|Clostridiales incertae sedis	186801|Clostridia	P	TIGRFAM phosphate ABC transporter, phosphate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WZS1_k127_1006128_2	649747.HMPREF0083_00884	7.816e-90	304.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli,26SNZ@186822|Paenibacillaceae	91061|Bacilli	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS1_k127_1011550_6	379066.GAU_2716	5.501e-36	143.0	COG1051@1|root,COG1051@2|Bacteria,1ZU0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS1_k127_1011550_2	869213.JCM21142_41393	2.207e-78	274.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,4NGUP@976|Bacteroidetes	976|Bacteroidetes	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
WZS1_k127_1011550_0	385682.AFSL01000102_gene55	2.645e-283	888.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
WZS1_k127_1011550_7	379066.GAU_1311	2.55e-34	137.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	cadC	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS1_k127_1011550_1	1122919.KB905585_gene3923	9.913e-184	602.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli,26QEF@186822|Paenibacillaceae	91061|Bacilli	P	COG2217 Cation transport ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS1_k127_1011550_5	1121920.AUAU01000013_gene1716	3.382e-43	170.0	COG4313@1|root,COG4313@2|Bacteria,3Y7K3@57723|Acidobacteria	57723|Acidobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1011550_3	1379270.AUXF01000001_gene2649	2.201e-65	230.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WZS1_k127_1011550_4	861299.J421_4358	3.887e-55	207.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS1_k127_1011550_8	861299.J421_4357	2.539e-30	128.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS1_k127_1050782_1	929556.Solca_3516	2.204e-62	228.0	COG2885@1|root,COG5403@1|root,COG2885@2|Bacteria,COG5403@2|Bacteria,4NIY2@976|Bacteroidetes,1IT5D@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF937,OmpA
WZS1_k127_1050782_0	518766.Rmar_1357	1.999e-105	355.0	COG1680@1|root,COG1680@2|Bacteria,4NJ0F@976|Bacteroidetes	976|Bacteroidetes	V	Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_1050782_2	1379270.AUXF01000001_gene2089	2.924e-51	188.0	COG1694@1|root,COG1694@2|Bacteria	2|Bacteria	FG	Mazg nucleotide pyrophosphohydrolase	ypjD	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	MazG
WZS1_k127_1050782_3	765912.Thimo_1861	8.46e-31	122.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,1S3SC@1236|Gammaproteobacteria,1X2HA@135613|Chromatiales	135613|Chromatiales	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WZS1_k127_1054942_0	861299.J421_3571	2.347e-299	932.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
WZS1_k127_1054942_3	1122927.KB895415_gene4600	6.598e-56	208.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
WZS1_k127_1054942_2	515635.Dtur_0577	3.2e-79	268.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,Hexapep,Hexapep_2
WZS1_k127_1054942_1	861299.J421_3570	4.306e-153	496.0	COG0399@1|root,COG0399@2|Bacteria,1ZT81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WZS1_k127_1074459_0	661478.OP10G_1529	1.436e-169	544.0	COG4805@1|root,COG4805@2|Bacteria	2|Bacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WZS1_k127_1074459_2	530564.Psta_4322	1.434e-52	191.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
WZS1_k127_1074459_1	861299.J421_6176	2.041e-54	203.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	ycgE	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WZS1_k127_1074459_3	1191523.MROS_0956	2.204e-29	128.0	28PR2@1|root,2ZCCZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1085466_0	379066.GAU_2322	9.733e-214	676.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1ZSS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
WZS1_k127_1085466_4	1121381.JNIV01000122_gene865	8.163e-70	241.0	COG0225@1|root,COG0225@2|Bacteria,1WK2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WZS1_k127_1085466_3	517418.Ctha_1616	5.274e-112	373.0	COG1858@1|root,COG1858@2|Bacteria,1FDVA@1090|Chlorobi	1090|Chlorobi	C	PFAM Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
WZS1_k127_1085466_6	379066.GAU_1377	5.83e-37	153.0	COG2050@1|root,COG2050@2|Bacteria,1ZV1I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
WZS1_k127_1085466_1	379066.GAU_1376	3.63e-132	437.0	COG2070@1|root,COG2070@2|Bacteria,1ZUN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
WZS1_k127_1085466_7	324602.Caur_1959	7.243e-31	126.0	2E3MN@1|root,33PAQ@2|Bacteria,2G91W@200795|Chloroflexi,377MD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1085466_8	1121930.AQXG01000001_gene1025	1.109e-10	67.0	2DT85@1|root,33J4K@2|Bacteria,4P8NM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1085466_2	1121920.AUAU01000013_gene1721	3.728e-119	392.0	COG0667@1|root,COG0667@2|Bacteria,3Y3TE@57723|Acidobacteria	57723|Acidobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS1_k127_1085466_5	411154.GFO_1406	3.983e-39	150.0	COG1277@1|root,COG1277@2|Bacteria,4NGGR@976|Bacteroidetes,1HXF5@117743|Flavobacteriia	976|Bacteroidetes	S	nitrous oxide	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2,ABC2_membrane_5
WZS1_k127_1085790_1	1089550.ATTH01000001_gene1831	3.269e-129	442.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
WZS1_k127_1085790_2	1183438.GKIL_3396	4.449e-49	191.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_ECF
WZS1_k127_1085790_0	861299.J421_0622	2.821e-234	740.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
WZS1_k127_1085790_3	234267.Acid_5191	1.962e-17	90.0	2AI77@1|root,318MJ@2|Bacteria,3Y7RV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1100438_3	526227.Mesil_0350	1.485e-31	135.0	COG2267@1|root,COG2267@2|Bacteria,1WJIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS1_k127_1100438_2	1379270.AUXF01000004_gene3063	1.287e-37	162.0	COG3204@1|root,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	5_nucleotid_C,Big_5,Exo_endo_phos,LTD,SdiA-regulated,VPEP
WZS1_k127_1100438_0	1121033.AUCF01000039_gene420	2.418e-166	542.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2JR1Q@204441|Rhodospirillales	204441|Rhodospirillales	G	PQQ-like domain	-	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
WZS1_k127_1100438_7	502025.Hoch_0529	7.478e-09	58.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
WZS1_k127_1100438_1	357808.RoseRS_1829	7.551e-126	413.0	COG0205@1|root,COG0205@2|Bacteria,2G6CJ@200795|Chloroflexi,374WW@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WZS1_k127_1100438_6	530564.Psta_1483	3.199e-24	109.0	COG2154@1|root,COG2154@2|Bacteria,2J0QH@203682|Planctomycetes	203682|Planctomycetes	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
WZS1_k127_1100438_5	344747.PM8797T_18209	4.158e-25	118.0	COG0720@1|root,COG0720@2|Bacteria,2IZMP@203682|Planctomycetes	203682|Planctomycetes	H	COG0720 6-pyruvoyl-tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WZS1_k127_1100438_4	1379270.AUXF01000003_gene3676	5.509e-27	121.0	COG0526@1|root,COG0526@2|Bacteria,1ZU4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CO	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_9
WZS1_k127_1100438_8	1121104.AQXH01000002_gene595	1.864e-08	63.0	COG3188@1|root,COG3188@2|Bacteria,4NFPY@976|Bacteroidetes	976|Bacteroidetes	NU	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1104759_4	1265502.KB905934_gene3233	1.597e-38	153.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria,4AFSH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
WZS1_k127_1104759_2	118166.JH976537_gene4652	4.241e-69	240.0	COG0500@1|root,COG0500@2|Bacteria,1G4ZC@1117|Cyanobacteria,1HHWQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS1_k127_1104759_0	378806.STAUR_5205	4.628e-292	910.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YXXC@29|Myxococcales	28221|Deltaproteobacteria	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WZS1_k127_1104759_1	1210884.HG799469_gene14124	1.142e-112	381.0	COG2326@1|root,COG2326@2|Bacteria,2IYWN@203682|Planctomycetes	203682|Planctomycetes	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
WZS1_k127_1104759_6	745411.B3C1_04570	1.544e-27	122.0	COG3714@1|root,COG3714@2|Bacteria,1PN0I@1224|Proteobacteria,1RNUV@1236|Gammaproteobacteria,1JB8C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	YhhN family	yhhN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	YhhN
WZS1_k127_1104759_7	194867.ALBQ01000013_gene725	8.312e-10	71.0	2EB2V@1|root,3353M@2|Bacteria,1QED4@1224|Proteobacteria,2U3RZ@28211|Alphaproteobacteria,2K1M2@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4403)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4403
WZS1_k127_1104759_5	497965.Cyan7822_1833	7.078e-35	141.0	COG0628@1|root,COG0628@2|Bacteria,1G1UA@1117|Cyanobacteria,3KH99@43988|Cyanothece	1117|Cyanobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS1_k127_111024_2	1111069.TCCBUS3UF1_1010	5.858e-94	314.0	COG1028@1|root,COG1028@2|Bacteria,1WIPQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
WZS1_k127_111024_1	56107.Cylst_2750	7.357e-112	371.0	COG2130@1|root,COG2130@2|Bacteria,1G0Z9@1117|Cyanobacteria,1HITK@1161|Nostocales	1117|Cyanobacteria	S	Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
WZS1_k127_111024_3	1267533.KB906734_gene3913	6.547e-25	119.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03286,ko:K03640	-	-	-	-	ko00000,ko02000	1.B.6,2.C.1.2	-	-	Laminin_G_3,OMP_b-brl_2,OmpA
WZS1_k127_111024_0	1379270.AUXF01000002_gene1760	3.476e-157	507.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZU9M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_1136470_0	861299.J421_2471	1.458e-293	913.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1ZTEZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WZS1_k127_1160995_6	404589.Anae109_0137	2.221e-19	94.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
WZS1_k127_1160995_3	861299.J421_2921	2.807e-67	236.0	COG0681@1|root,COG0681@2|Bacteria,1ZTQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WZS1_k127_1160995_2	404589.Anae109_2847	6.085e-124	411.0	COG0823@1|root,COG0823@2|Bacteria,1QW3I@1224|Proteobacteria,42YA5@68525|delta/epsilon subdivisions,2WU6I@28221|Deltaproteobacteria,2Z3J0@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
WZS1_k127_1160995_4	1128421.JAGA01000004_gene2555	4.452e-59	215.0	COG1225@1|root,COG1225@2|Bacteria,2NPEE@2323|unclassified Bacteria	2|Bacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15,2.7.7.42,2.7.7.89	ko:K00982,ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WZS1_k127_1160995_1	861299.J421_4536	9.729e-134	446.0	COG2866@1|root,COG2866@2|Bacteria,1ZT9V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WZS1_k127_1160995_5	1121033.AUCF01000004_gene4853	2.006e-54	211.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
WZS1_k127_1160995_7	679935.Alfi_0024	1.647e-07	66.0	COG1538@1|root,COG1538@2|Bacteria,4NF4X@976|Bacteroidetes,2FN2J@200643|Bacteroidia	976|Bacteroidetes	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WZS1_k127_1160995_0	1379698.RBG1_1C00001G1725	2.426e-261	831.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
WZS1_k127_1161932_2	1144305.PMI02_03548	0.0001479	46.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,2K0HW@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
WZS1_k127_1161932_0	234267.Acid_7338	1.45e-119	400.0	COG1228@1|root,COG1228@2|Bacteria,3Y39J@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_1161932_1	234267.Acid_7167	2.658e-107	364.0	COG5549@1|root,COG5549@2|Bacteria,3Y2IY@57723|Acidobacteria	57723|Acidobacteria	O	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
WZS1_k127_1163233_6	861299.J421_6016	4.434e-33	131.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1163233_8	190650.CC_2458	4.91e-09	64.0	2E902@1|root,3339H@2|Bacteria,1N9U6@1224|Proteobacteria,2UFG4@28211|Alphaproteobacteria,2KH8D@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1163233_5	1123322.KB904658_gene1187	7.129e-41	169.0	COG1807@1|root,COG1807@2|Bacteria,2GP96@201174|Actinobacteria	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WZS1_k127_1163233_1	861299.J421_2200	6.902e-154	499.0	COG0673@1|root,COG0673@2|Bacteria,1ZSRB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WZS1_k127_1163233_0	1440774.Y900_021270	3.423e-157	511.0	COG0433@1|root,COG0433@2|Bacteria,2GM12@201174|Actinobacteria,236SN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
WZS1_k127_1163233_7	379066.GAU_3609	5.44e-26	120.0	COG3137@1|root,COG3137@2|Bacteria,1ZUT1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
WZS1_k127_1163233_3	909663.KI867149_gene3383	2.39e-54	196.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,2MRIV@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Large-conductance mechanosensitive channel, MscL	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WZS1_k127_1163233_2	861299.J421_2861	1.012e-88	302.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1ZTKD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11
WZS1_k127_1163233_4	1463857.JOFZ01000018_gene1447	1.907e-43	162.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
WZS1_k127_1163806_4	379066.GAU_2351	4.899e-52	192.0	COG1989@1|root,COG1989@2|Bacteria,1ZT9K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WZS1_k127_1163806_5	861299.J421_3833	1.643e-48	186.0	COG0566@1|root,COG0566@2|Bacteria,1ZTVA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNA 2'-O ribose methyltransferase substrate binding	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WZS1_k127_1163806_2	717605.Theco_1937	9.148e-75	275.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26TPG@186822|Paenibacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WZS1_k127_1163806_0	1391647.AVSV01000016_gene1040	1.885e-130	432.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
WZS1_k127_1163806_1	379066.GAU_2355	1.171e-105	354.0	COG1816@1|root,COG1816@2|Bacteria,1ZSQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenosine/AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
WZS1_k127_1163806_7	379066.GAU_2356	4.476e-05	52.0	290N8@1|root,2ZNAK@2|Bacteria,1ZU7A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1163806_6	1379270.AUXF01000001_gene2712	1.143e-08	63.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS1_k127_1163806_3	1379270.AUXF01000003_gene3568	2.9e-72	249.0	COG0745@1|root,COG0745@2|Bacteria,1ZTC6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS1_k127_1198469_2	861299.J421_3974	1.216e-34	134.0	COG0082@1|root,COG0082@2|Bacteria,1ZT39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
WZS1_k127_1198469_0	1379270.AUXF01000003_gene3398	1.317e-137	459.0	COG4796@1|root,COG4796@2|Bacteria,1ZSRT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	AMIN domain	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,Secretin,Secretin_N
WZS1_k127_1198469_5	379066.GAU_2515	1.164e-17	89.0	2F6AC@1|root,33YU1@2|Bacteria,1ZTY6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1198469_4	1379270.AUXF01000003_gene3396	5.153e-22	103.0	COG3167@1|root,COG3167@2|Bacteria,1ZTZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Pilus assembly protein, PilO	-	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
WZS1_k127_1198469_3	379066.GAU_2517	4.723e-31	136.0	COG3166@1|root,COG3166@2|Bacteria,1ZTR8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Fimbrial assembly protein (PilN)	-	-	-	-	-	-	-	-	-	-	-	-	PilN
WZS1_k127_1198469_1	1379270.AUXF01000003_gene3394	4.997e-87	293.0	COG4972@1|root,COG4972@2|Bacteria,1ZSYA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
WZS1_k127_1225654_2	1210884.HG799465_gene11339	5.885e-25	107.0	COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
WZS1_k127_1225654_0	379066.GAU_3397	6.006e-200	647.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_1225654_3	1206733.BAGC01000056_gene2764	5.774e-16	91.0	COG0515@1|root,COG0515@2|Bacteria,2GJTV@201174|Actinobacteria,4FVEP@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4352,Pkinase,TPR_10
WZS1_k127_1225654_1	861299.J421_2852	8.192e-35	141.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_2852|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WZS1_k127_1228941_3	1121920.AUAU01000005_gene1038	1.596e-63	229.0	COG1228@1|root,COG1228@2|Bacteria,3Y4IP@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_1228941_4	391625.PPSIR1_25966	1.197e-52	198.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,42UHJ@68525|delta/epsilon subdivisions,2WT4S@28221|Deltaproteobacteria,2YUXZ@29|Myxococcales	28221|Deltaproteobacteria	K	Arabinose-binding domain of AraC transcription regulator, N-term	oruR2	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
WZS1_k127_1228941_5	330214.NIDE3841	2.78e-50	179.0	COG3549@1|root,COG3549@2|Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	higB	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
WZS1_k127_1228941_7	330214.NIDE3842	8.179e-48	175.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
WZS1_k127_1228941_8	1173024.KI912148_gene3847	2.691e-40	158.0	COG0317@1|root,COG0317@2|Bacteria,1G0F8@1117|Cyanobacteria,1JKIF@1189|Stigonemataceae	1117|Cyanobacteria	KT	HD domain	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
WZS1_k127_1228941_6	765911.Thivi_3024	9.869e-49	180.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,1S6K5@1236|Gammaproteobacteria,1X0TT@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
WZS1_k127_1228941_11	748658.KB907319_gene719	2.956e-08	61.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,1SATT@1236|Gammaproteobacteria,1X26V@135613|Chromatiales	135613|Chromatiales	S	Large family of predicted nucleotide-binding domains	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
WZS1_k127_1228941_2	1255043.TVNIR_3312	9.173e-73	251.0	COG4974@1|root,COG4974@2|Bacteria,1MZES@1224|Proteobacteria,1S9MN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
WZS1_k127_1228941_0	765911.Thivi_1573	6.654e-161	520.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RM9J@1236|Gammaproteobacteria,1WWJY@135613|Chromatiales	135613|Chromatiales	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
WZS1_k127_1228941_10	521045.Kole_0088	3.05e-29	121.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
WZS1_k127_1230279_3	1267534.KB906757_gene743	1.082e-31	129.0	COG0492@1|root,COG0492@2|Bacteria,3Y2NX@57723|Acidobacteria,2JI8S@204432|Acidobacteriia	204432|Acidobacteriia	O	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
WZS1_k127_1230279_2	379066.GAU_2793	4.817e-96	321.0	COG2321@1|root,COG2321@2|Bacteria,1ZSN1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
WZS1_k127_1230279_1	861299.J421_3829	9.556e-116	386.0	COG2733@1|root,COG2733@2|Bacteria,1ZTAK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
WZS1_k127_1230279_0	945713.IALB_0430	2.38e-208	658.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	csdA	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS1_k127_1230279_4	1049564.TevJSym_ae00750	0.0002301	52.0	28TB7@1|root,2ZFJR@2|Bacteria,1PACM@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1230916_7	1210884.HG799475_gene15250	2.984e-100	335.0	COG0405@1|root,COG0405@2|Bacteria,2IWWP@203682|Planctomycetes	203682|Planctomycetes	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WZS1_k127_1230916_0	76114.ebA2164	0.0	1272.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,2KV0M@206389|Rhodocyclales	206389|Rhodocyclales	C	NADH flavin	abmA	-	1.14.13.40	ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
WZS1_k127_1230916_4	438753.AZC_3188	5.087e-142	458.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	MA20_38145	-	-	-	-	-	-	-	-	-	-	-	ECH_1
WZS1_k127_1230916_3	748247.AZKH_1860	2.595e-190	599.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2VIAN@28216|Betaproteobacteria,2KY4X@206389|Rhodocyclales	206389|Rhodocyclales	C	Acyl-CoA dehydrogenase, C-terminal domain	abmD	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS1_k127_1230916_8	883126.HMPREF9710_02750	3.085e-45	178.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2VSJ7@28216|Betaproteobacteria,47795@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	abmE	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WZS1_k127_1230916_2	62928.azo1996	1.186e-270	841.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bclA_1	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
WZS1_k127_1230916_5	234267.Acid_0802	8.125e-141	468.0	COG0624@1|root,COG0624@2|Bacteria,3Y4G2@57723|Acidobacteria	57723|Acidobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_1230916_1	760192.Halhy_1605	0.0	1125.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,1IVPS@117747|Sphingobacteriia	976|Bacteroidetes	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WZS1_k127_1230916_6	247639.MGP2080_08314	1.042e-136	447.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1JA3P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_1239156_6	861299.J421_4533	8.859e-22	99.0	COG0506@1|root,COG0506@2|Bacteria,1ZT6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
WZS1_k127_1239156_2	861299.J421_4263	7.74e-209	661.0	COG2234@1|root,COG2234@2|Bacteria,1ZT06@142182|Gemmatimonadetes	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WZS1_k127_1239156_1	1379270.AUXF01000001_gene2467	3.429e-222	711.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1ZT1A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
WZS1_k127_1239156_3	379066.GAU_2857	9.243e-158	508.0	COG0183@1|root,COG0183@2|Bacteria,1ZSW1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Thiolase, C-terminal domain	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
WZS1_k127_1239156_7	1031711.RSPO_c02228	7.29e-17	93.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,2VR4M@28216|Betaproteobacteria,1K2UH@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,TehB
WZS1_k127_1239156_4	1297742.A176_06644	3.387e-131	448.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,2YTWC@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
WZS1_k127_1239156_5	391037.Sare_4070	3.913e-34	139.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4DAGY@85008|Micromonosporales	201174|Actinobacteria	C	dehydrogenase, E1 component	kgd	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0030312,GO:0032991,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0050439,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:1902494,GO:1990204,GO:1990234	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1248c	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
WZS1_k127_1239156_0	1380390.JIAT01000009_gene1279	3.828e-294	922.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CPG1@84995|Rubrobacteria	84995|Rubrobacteria	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,Biotin_lipoyl,E1_dh,E3_binding,OxoGdeHyase_C,Transket_pyr
WZS1_k127_1259153_1	945713.IALB_2033	4.801e-59	211.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
WZS1_k127_1259153_0	379066.GAU_1492	0.0	1180.0	COG0542@1|root,COG0542@2|Bacteria,1ZT9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WZS1_k127_1259153_2	1121451.DESAM_22484	4.131e-05	49.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2M8QA@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
WZS1_k127_1267298_4	926550.CLDAP_33370	1.811e-13	75.0	COG0500@1|root,COG2226@2|Bacteria,2G948@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS1_k127_1267298_0	404589.Anae109_1600	8.277e-96	332.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,Cupin_6,HTH_18
WZS1_k127_1267298_1	1183438.GKIL_3076	1.814e-46	175.0	COG0431@1|root,COG0431@2|Bacteria,1G81A@1117|Cyanobacteria	1117|Cyanobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WZS1_k127_1267298_3	404589.Anae109_3939	2.047e-33	144.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,HTH_IclR,IclR,MRJP,NHL,SGL,fn3
WZS1_k127_1267298_2	395494.Galf_2061	3.72e-38	146.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ9H@28216|Betaproteobacteria,44VRB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS1_k127_1302995_4	1297742.A176_04627	7.405e-11	74.0	COG0457@1|root,COG0457@2|Bacteria,1Q2MK@1224|Proteobacteria,43886@68525|delta/epsilon subdivisions,2X3HX@28221|Deltaproteobacteria,2YW6E@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1302995_3	861299.J421_4047	9.36e-83	294.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
WZS1_k127_1302995_1	861299.J421_4047	5.788e-103	375.0	COG1680@1|root,COG1680@2|Bacteria,1ZTJS@142182|Gemmatimonadetes	2|Bacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Cu_amine_oxidN1,DUF3471
WZS1_k127_1302995_0	861299.J421_6096	2.223e-233	766.0	COG3653@1|root,COG3653@2|Bacteria,1ZUFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_1302995_2	379066.GAU_1161	3.73e-93	314.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSZA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_1303822_2	1034943.BN1094_00934	2.551e-13	83.0	COG1879@1|root,COG2373@1|root,COG3419@1|root,COG1879@2|Bacteria,COG2373@2|Bacteria,COG3419@2|Bacteria,1QUUR@1224|Proteobacteria,1T21Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Psort location OuterMembrane, score	eaeH	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_2,IAT_beta,Invasin_D3,LysM
WZS1_k127_1303822_0	394221.Mmar10_1563	2.178e-31	138.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,43ZAE@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS1_k127_1303822_1	379066.GAU_1055	1.472e-17	96.0	COG2885@1|root,COG5492@1|root,COG2885@2|Bacteria,COG5492@2|Bacteria,1ZUMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MN	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,OmpA
WZS1_k127_1303822_3	523791.Kkor_0544	4.175e-10	64.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1XHA8@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
WZS1_k127_1307659_8	349163.Acry_0362	5.258e-05	49.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,2JQJ9@204441|Rhodospirillales	204441|Rhodospirillales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WZS1_k127_1307659_6	484770.UFO1_1869	1.253e-36	142.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4H4SD@909932|Negativicutes	909932|Negativicutes	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WZS1_k127_1307659_7	1321781.HMPREF1985_02289	1.608e-14	74.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4H5N5@909932|Negativicutes	909932|Negativicutes	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WZS1_k127_1307659_2	379066.GAU_1878	1.314e-68	239.0	COG0290@1|root,COG0290@2|Bacteria,1ZTM6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WZS1_k127_1307659_3	1297865.APJD01000015_gene3469	8.564e-65	238.0	COG3571@1|root,COG3571@2|Bacteria,1RD20@1224|Proteobacteria,2U1XJ@28211|Alphaproteobacteria,3JSHJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolase of the alpha beta-hydrolase fold	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,DLH,Thioesterase
WZS1_k127_1307659_0	861299.J421_3449	5.182e-107	369.0	COG0491@1|root,COG0491@2|Bacteria,1ZT7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS1_k127_1307659_4	1379270.AUXF01000006_gene80	6.204e-51	191.0	COG0847@1|root,COG0847@2|Bacteria,1ZTNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
WZS1_k127_1307659_1	379066.GAU_1881	2.095e-71	246.0	COG2344@1|root,COG2344@2|Bacteria,1ZTJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WZS1_k127_1307659_5	1379270.AUXF01000006_gene78	1.493e-46	175.0	COG0030@1|root,COG0030@2|Bacteria,1ZT2M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WZS1_k127_1316487_5	290397.Adeh_3472	8.454e-06	53.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N5C@68525|delta/epsilon subdivisions,2WM18@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
WZS1_k127_1316487_1	42256.RradSPS_3078	7.666e-27	113.0	COG0640@1|root,COG0640@2|Bacteria,2GYV0@201174|Actinobacteria,4CQNZ@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
WZS1_k127_1316487_4	945713.IALB_2856	4.121e-06	55.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF3240,P-II
WZS1_k127_1316487_3	1379270.AUXF01000001_gene2733	1.003e-14	77.0	29X7I@1|root,30IWS@2|Bacteria,1ZV88@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WZS1_k127_1316487_0	1379270.AUXF01000001_gene2734	0.0	1491.0	COG0841@1|root,COG0841@2|Bacteria,1ZUDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WZS1_k127_1316487_2	925409.KI911562_gene334	2.984e-21	102.0	COG0845@1|root,COG0845@2|Bacteria,4NF23@976|Bacteroidetes,1IU9I@117747|Sphingobacteriia	976|Bacteroidetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WZS1_k127_132577_2	861299.J421_3080	1.526e-123	399.0	COG0206@1|root,COG0206@2|Bacteria,1ZSNH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WZS1_k127_132577_3	861299.J421_3079	1.852e-120	407.0	COG0849@1|root,COG0849@2|Bacteria,1ZSRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WZS1_k127_132577_8	379066.GAU_1430	1.479e-25	119.0	COG1589@1|root,COG1589@2|Bacteria,1ZTRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell division protein FtsQ	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
WZS1_k127_132577_4	379066.GAU_1429	1.135e-108	372.0	COG0773@1|root,COG0773@2|Bacteria,1ZSQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS1_k127_132577_7	861299.J421_3076	9.633e-69	261.0	COG0707@1|root,COG0707@2|Bacteria,1ZSW5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WZS1_k127_132577_6	1379270.AUXF01000005_gene689	1.843e-70	257.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WZS1_k127_132577_0	861299.J421_3074	8.798e-132	460.0	COG0771@1|root,COG0771@2|Bacteria,1ZT38@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS1_k127_132577_1	861299.J421_3073	2.232e-129	423.0	COG0472@1|root,COG0472@2|Bacteria,1ZT4Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4
WZS1_k127_132577_5	1379270.AUXF01000005_gene686	9.286e-90	313.0	COG0770@1|root,COG0770@2|Bacteria,1ZT1U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS1_k127_132577_9	861299.J421_3071	6.132e-08	53.0	COG0769@1|root,COG0769@2|Bacteria,1ZSS3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS1_k127_1344923_4	1123054.KB907705_gene2416	1.617e-05	50.0	COG0729@1|root,COG0729@2|Bacteria,1QVUN@1224|Proteobacteria,1T2JF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
WZS1_k127_1344923_3	1000565.METUNv1_03477	3.353e-35	139.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,2VUHB@28216|Betaproteobacteria,2KYYM@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1344923_2	1121920.AUAU01000022_gene2463	1.418e-48	183.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1099	AAA_28,Thymidylate_kin
WZS1_k127_1344923_1	861299.J421_1000	7.804e-120	391.0	COG0010@1|root,COG0010@2|Bacteria,1ZTB1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WZS1_k127_1344923_0	1242864.D187_000308	5.392e-218	696.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2WWD4@28221|Deltaproteobacteria,2YTYG@29|Myxococcales	28221|Deltaproteobacteria	S	oligopeptide transporter, OPT family	-	-	-	-	-	-	-	-	-	-	-	-	OPT
WZS1_k127_1356552_0	1379270.AUXF01000002_gene1567	2.427e-87	317.0	COG0515@1|root,COG0515@2|Bacteria,1ZUCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_1365832_5	861299.J421_2370	4.384e-06	54.0	2F95J@1|root,341H1@2|Bacteria,1ZTZZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1365832_3	861299.J421_2372	2.083e-54	198.0	COG0328@1|root,COG0328@2|Bacteria,1ZTI8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
WZS1_k127_1365832_1	2074.JNYD01000022_gene1521	3.989e-99	333.0	COG0709@1|root,COG0709@2|Bacteria,2GNP4@201174|Actinobacteria,4DYK1@85010|Pseudonocardiales	201174|Actinobacteria	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
WZS1_k127_1365832_4	1379698.RBG1_1C00001G0351	4.428e-29	128.0	COG2215@1|root,COG2215@2|Bacteria,2NRP3@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the NiCoT transporter (TC 2.A.52) family	ureH	-	-	ko:K07241	-	-	-	-	ko00000,ko02000	2.A.52.1	-	-	DsbD_2,NicO
WZS1_k127_1365832_0	861299.J421_2390	2.127e-116	385.0	COG0604@1|root,COG0604@2|Bacteria,1ZT6R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WZS1_k127_1365832_2	1379270.AUXF01000002_gene1817	1.661e-54	200.0	COG0668@1|root,COG0668@2|Bacteria,1ZSU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
WZS1_k127_137902_1	861299.J421_3116	1.397e-182	580.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1ZT7J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
WZS1_k127_137902_8	861299.J421_3115	1.426e-50	187.0	COG0307@1|root,COG0307@2|Bacteria,1ZTQM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
WZS1_k127_137902_6	861299.J421_3114	6.521e-91	325.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1ZSNI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
WZS1_k127_137902_5	861299.J421_3112	1.786e-97	342.0	COG0150@1|root,COG0150@2|Bacteria,1ZSQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AIR synthase related protein, C-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WZS1_k127_137902_4	861299.J421_3111	1.851e-107	358.0	COG0524@1|root,COG0524@2|Bacteria,1ZSUT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WZS1_k127_137902_2	1118054.CAGW01000043_gene1092	6.25e-145	480.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli,26R9D@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WZS1_k127_137902_11	452637.Oter_3821	3.789e-19	95.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WZS1_k127_137902_9	1089550.ATTH01000001_gene1602	8.877e-44	168.0	COG0400@1|root,COG0400@2|Bacteria,4NHWT@976|Bacteroidetes,1FJF1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Serine hydrolase (FSH1)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,FSH1
WZS1_k127_137902_10	1379270.AUXF01000001_gene2745	6e-21	103.0	COG5349@1|root,COG5349@2|Bacteria,1ZU3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
WZS1_k127_137902_0	861299.J421_3107	7.314e-211	672.0	COG1884@1|root,COG1884@2|Bacteria,1ZT5I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WZS1_k127_137902_3	379066.GAU_1456	1.529e-120	395.0	COG0158@1|root,COG0158@2|Bacteria,1ZTAZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
WZS1_k127_137902_7	861299.J421_3104	1.757e-81	297.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1ZSMY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,Lactamase_B
WZS1_k127_137902_12	498761.HM1_0267	3.815e-06	50.0	2DNY2@1|root,32ZR4@2|Bacteria,1VEGZ@1239|Firmicutes,24RGC@186801|Clostridia	186801|Clostridia	S	PFAM Late competence development protein ComFB	comFB	-	-	ko:K02241	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComFB
WZS1_k127_1404498_11	1379270.AUXF01000005_gene654	3.911e-33	145.0	COG0037@1|root,COG0037@2|Bacteria,1ZTK2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
WZS1_k127_1404498_3	1210884.HG799466_gene13015	5.994e-102	339.0	COG0053@1|root,COG0053@2|Bacteria,2IY05@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WZS1_k127_1404498_5	383372.Rcas_1067	2.021e-69	256.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
WZS1_k127_1404498_0	1128421.JAGA01000001_gene2399	1.081e-172	568.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4620	FAA_hydrolase,FAA_hydrolase_N
WZS1_k127_1404498_9	1128421.JAGA01000001_gene2398	3.928e-64	230.0	COG0124@1|root,COG0124@2|Bacteria	2|Bacteria	J	histidine-tRNA ligase activity	hisZ	-	6.1.1.21	ko:K01892,ko:K02502	ko00340,ko00970,ko01100,ko01110,ko01230,map00340,map00970,map01100,map01110,map01230	M00026,M00359,M00360	R01071,R03655	RC00055,RC00523,RC02819,RC03200	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
WZS1_k127_1404498_8	1236902.ANAS01000005_gene4523	8.596e-65	240.0	COG0833@1|root,COG0833@2|Bacteria,2I4B6@201174|Actinobacteria	201174|Actinobacteria	E	amino acid	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
WZS1_k127_1404498_1	278963.ATWD01000002_gene822	5.386e-121	423.0	COG3246@1|root,COG3246@2|Bacteria,3Y859@57723|Acidobacteria	57723|Acidobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
WZS1_k127_1404498_10	460265.Mnod_3695	6.876e-64	230.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,1JQP3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
WZS1_k127_1404498_7	392499.Swit_3073	6.391e-67	241.0	COG1028@1|root,COG1028@2|Bacteria,1MX30@1224|Proteobacteria,2TR09@28211|Alphaproteobacteria,2K5MP@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WZS1_k127_1404498_4	379066.GAU_3347	1.275e-84	302.0	COG2362@1|root,COG2362@2|Bacteria	2|Bacteria	E	D-aminopeptidase	dppA	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
WZS1_k127_1404498_2	861299.J421_5977	1.052e-116	398.0	COG0665@1|root,COG0665@2|Bacteria,1ZUQF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WZS1_k127_1404498_6	887062.HGR_07776	1.966e-67	237.0	COG2040@1|root,COG2040@2|Bacteria,1QTE6@1224|Proteobacteria,2VNST@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Homocysteine S-methyltransferase	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
WZS1_k127_1405137_8	1461693.ATO10_14524	1.014e-07	60.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Protein conserved in bacteria	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
WZS1_k127_1405137_2	1379270.AUXF01000002_gene1485	7.809e-69	258.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	blaB3	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS1_k127_1405137_4	861299.J421_3139	1.95e-51	186.0	COG0590@1|root,COG0590@2|Bacteria,1ZTW9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam
WZS1_k127_1405137_7	700598.Niako_6249	7.623e-14	83.0	COG0330@1|root,COG0330@2|Bacteria,4NFNB@976|Bacteroidetes,1IQR6@117747|Sphingobacteriia	976|Bacteroidetes	O	COG0330 Membrane protease subunits stomatin prohibitin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WZS1_k127_1405137_0	28072.Nos7524_4416	0.0	1102.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1G092@1117|Cyanobacteria,1HMF6@1161|Nostocales	1117|Cyanobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
WZS1_k127_1405137_9	411901.BACCAC_03171	4.811e-06	54.0	2A76E@1|root,30W2E@2|Bacteria,4P9FC@976|Bacteroidetes,2FZNB@200643|Bacteroidia,4AUSK@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1405137_1	861299.J421_0076	2.424e-135	436.0	COG2041@1|root,COG2041@2|Bacteria,1ZTGI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
WZS1_k127_1405137_5	1384054.N790_00725	1.864e-45	177.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,1RS9K@1236|Gammaproteobacteria,1X631@135614|Xanthomonadales	135614|Xanthomonadales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
WZS1_k127_1405137_3	379066.GAU_1514	1.278e-58	217.0	COG2065@1|root,COG2065@2|Bacteria,1ZTHG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
WZS1_k127_1405137_6	861299.J421_3142	2.258e-26	110.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WZS1_k127_1424116_2	861299.J421_6209	6.649e-90	312.0	COG2234@1|root,COG2234@2|Bacteria,1ZSXY@142182|Gemmatimonadetes	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WZS1_k127_1424116_0	379066.GAU_3308	1.925e-166	534.0	COG2234@1|root,COG2234@2|Bacteria,1ZTDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WZS1_k127_1424116_1	378806.STAUR_5297	2.214e-131	431.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,42YGK@68525|delta/epsilon subdivisions,2WU4M@28221|Deltaproteobacteria,2YWRP@29|Myxococcales	28221|Deltaproteobacteria	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
WZS1_k127_1443116_1	118005.AWNK01000003_gene2461	7.125e-40	155.0	COG0780@1|root,COG0780@2|Bacteria	2|Bacteria	G	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
WZS1_k127_1443116_4	1068978.AMETH_5249	3.801e-06	60.0	COG3629@1|root,COG3629@2|Bacteria,2I2QB@201174|Actinobacteria,4E8EJ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
WZS1_k127_1443116_0	290397.Adeh_1417	1.015e-206	674.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS1_k127_1443116_2	1121382.JQKG01000008_gene969	4.875e-27	124.0	COG1309@1|root,COG1309@2|Bacteria,1WN5A@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1443116_3	643648.Slip_1285	1.902e-17	87.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,42JK9@68298|Syntrophomonadaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WZS1_k127_1457346_1	861299.J421_5794	1.146e-14	88.0	COG0515@1|root,COG0515@2|Bacteria,1ZUMJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
WZS1_k127_1457346_0	479434.Sthe_0854	1.468e-99	346.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi,27Z0M@189775|Thermomicrobia	189775|Thermomicrobia	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WZS1_k127_1464690_1	861299.J421_1147	4.102e-61	216.0	COG0515@1|root,COG0515@2|Bacteria,1ZT9E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_1464690_2	1379270.AUXF01000002_gene1195	3.246e-53	195.0	COG0461@1|root,COG0461@2|Bacteria,1ZTMR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
WZS1_k127_1464690_3	379066.GAU_0004	1.726e-46	181.0	COG2207@1|root,COG2207@2|Bacteria,1ZTPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WZS1_k127_1464690_4	517417.Cpar_1903	1.056e-39	159.0	COG0744@1|root,COG0744@2|Bacteria,1FDQX@1090|Chlorobi	1090|Chlorobi	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
WZS1_k127_1464690_0	861299.J421_1072	1.466e-166	529.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
WZS1_k127_1476085_2	1519464.HY22_10360	1.297e-178	570.0	COG0154@1|root,COG0154@2|Bacteria,1FDMC@1090|Chlorobi	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS1_k127_1476085_5	378806.STAUR_4782	5.98e-117	400.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2X5RQ@28221|Deltaproteobacteria,2YYRW@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WZS1_k127_1476085_4	861299.J421_0427	3.468e-153	506.0	COG1449@1|root,COG1449@2|Bacteria,1ZTEQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
WZS1_k127_1476085_6	1303518.CCALI_02107	2.563e-114	390.0	COG1543@1|root,COG1543@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576	2.4.1.18	ko:K03406,ko:K16149	ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko02035	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
WZS1_k127_1476085_3	379066.GAU_1365	3.002e-160	519.0	COG0297@1|root,COG0297@2|Bacteria,1ZUKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WZS1_k127_1476085_0	1379270.AUXF01000005_gene635	6.663e-294	930.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
WZS1_k127_1476085_1	1380394.JADL01000001_gene2789	6.881e-256	805.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2JPZX@204441|Rhodospirillales	204441|Rhodospirillales	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WZS1_k127_1476085_7	518766.Rmar_0511	3.026e-12	70.0	COG2133@1|root,COG2133@2|Bacteria,4NDV1@976|Bacteroidetes	976|Bacteroidetes	G	Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WZS1_k127_1503090_2	1283300.ATXB01000001_gene46	1.995e-20	102.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,1RPGN@1236|Gammaproteobacteria,1XGXV@135618|Methylococcales	135618|Methylococcales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WZS1_k127_1503090_1	1410668.JNKC01000004_gene46	1.661e-36	143.0	COG4852@1|root,COG4852@2|Bacteria,1VBU5@1239|Firmicutes,24Q4S@186801|Clostridia,36S0J@31979|Clostridiaceae	186801|Clostridia	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
WZS1_k127_1503090_0	313603.FB2170_10751	1.723e-67	241.0	COG0010@1|root,COG0010@2|Bacteria,4NHDP@976|Bacteroidetes,1HYJ0@117743|Flavobacteriia,2PGYP@252356|Maribacter	976|Bacteroidetes	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
WZS1_k127_1503090_4	309807.SRU_1148	3.452e-05	55.0	2A56M@1|root,30TVJ@2|Bacteria,4PF8T@976|Bacteroidetes,1FKAU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1503090_3	1502850.FG91_00620	1.475e-16	92.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,2UHB3@28211|Alphaproteobacteria,2KBAH@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1536334_5	379066.GAU_0930	1.763e-84	286.0	COG0785@1|root,COG0785@2|Bacteria,1ZTJC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WZS1_k127_1536334_8	1379270.AUXF01000004_gene2965	1.455e-37	149.0	COG0735@1|root,COG0735@2|Bacteria,1ZTN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WZS1_k127_1536334_2	215803.DB30_2054	2.135e-141	468.0	COG1915@1|root,COG1915@2|Bacteria,1PZ72@1224|Proteobacteria,42MME@68525|delta/epsilon subdivisions,2WJSV@28221|Deltaproteobacteria,2YYT4@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
WZS1_k127_1536334_6	396588.Tgr7_0241	3.956e-82	297.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,1RQYX@1236|Gammaproteobacteria,1X2PP@135613|Chromatiales	135613|Chromatiales	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WZS1_k127_1536334_11	187272.Mlg_2728	1.31e-07	54.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,1RQYX@1236|Gammaproteobacteria,1X2PP@135613|Chromatiales	135613|Chromatiales	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WZS1_k127_1536334_0	861299.J421_2825	7.142e-212	685.0	COG1198@1|root,COG1198@2|Bacteria,1ZTE9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
WZS1_k127_1536334_3	1379270.AUXF01000004_gene2972	3.982e-112	375.0	COG4948@1|root,COG4948@2|Bacteria,1ZSKY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
WZS1_k127_1536334_7	861299.J421_2819	2.81e-77	269.0	COG0123@1|root,COG0123@2|Bacteria,1ZSKN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WZS1_k127_1536334_9	861299.J421_2817	2.155e-17	84.0	2FC5K@1|root,3449E@2|Bacteria,1ZU4V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1536334_10	1122222.AXWR01000029_gene2249	3.2e-16	87.0	COG3824@1|root,COG3824@2|Bacteria,1WJSP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
WZS1_k127_1536334_1	861299.J421_2810	2.002e-211	668.0	COG0423@1|root,COG0423@2|Bacteria,1ZT4P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
WZS1_k127_1536334_4	1379270.AUXF01000004_gene2994	9.733e-98	323.0	COG0104@1|root,COG0104@2|Bacteria,1ZSNV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WZS1_k127_1542945_2	861299.J421_3416	1.916e-44	173.0	COG2265@1|root,COG2265@2|Bacteria,1ZSPC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
WZS1_k127_1542945_1	309801.trd_A0778	6.583e-140	465.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi,27YU8@189775|Thermomicrobia	189775|Thermomicrobia	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WZS1_k127_1542945_0	861299.J421_3418	2.081e-252	788.0	COG4799@1|root,COG4799@2|Bacteria,1ZTGE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WZS1_k127_1570646_7	861299.J421_0065	2.039e-67	244.0	COG2120@1|root,COG2120@2|Bacteria,1ZT6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WZS1_k127_1570646_1	379066.GAU_0426	1.519e-105	356.0	COG0477@1|root,COG2814@2|Bacteria,1ZT84@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS1_k127_1570646_0	861299.J421_3665	1.369e-218	711.0	COG1164@1|root,COG1164@2|Bacteria,1ZTDD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
WZS1_k127_1570646_11	1268622.AVS7_03812	2.495e-24	105.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,4AEXW@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WZS1_k127_1570646_10	1379270.AUXF01000001_gene2224	1.004e-28	118.0	COG1278@1|root,COG1278@2|Bacteria,1ZTZ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WZS1_k127_1570646_6	379066.GAU_1151	5.565e-75	276.0	COG0515@1|root,COG0515@2|Bacteria,1ZTB4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_1570646_9	1499967.BAYZ01000038_gene2269	2.607e-35	152.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP,PAS_3,PAS_9
WZS1_k127_1570646_3	272568.GDI2954	1.686e-99	328.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2JRQP@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
WZS1_k127_1570646_2	631362.Thi970DRAFT_03853	1.904e-103	341.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1WXBT@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
WZS1_k127_1570646_5	1242864.D187_010288	1.049e-85	310.0	COG1090@1|root,COG4276@1|root,COG1090@2|Bacteria,COG4276@2|Bacteria,1MUB4@1224|Proteobacteria,42PQ2@68525|delta/epsilon subdivisions,2WK6V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
WZS1_k127_1570646_4	460265.Mnod_1497	3.525e-90	310.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,2TTFW@28211|Alphaproteobacteria,1JQV8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBS,Peptidase_M50
WZS1_k127_1570646_8	1379270.AUXF01000003_gene3807	1.027e-46	188.0	COG1166@1|root,COG1166@2|Bacteria,1ZST1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
WZS1_k127_1578560_0	861299.J421_4433	1.99e-275	861.0	COG1643@1|root,COG1643@2|Bacteria,1ZSN8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Atp-dependent helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1599147_1	861299.J421_3420	5.213e-141	451.0	COG0539@1|root,COG0539@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WZS1_k127_1599147_0	671143.DAMO_2917	4.219e-182	580.0	COG0667@1|root,COG1331@1|root,COG0667@2|Bacteria,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,GlcNAc_2-epim,Thioredox_DsbH
WZS1_k127_1603194_8	861299.J421_3986	7.308e-20	96.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pilE	-	-	ko:K02456,ko:K02650,ko:K02655	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl
WZS1_k127_1603194_0	1379698.RBG1_1C00001G1210	4.075e-136	457.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	nla19	-	-	ko:K02667,ko:K07713,ko:K07714,ko:K19641	ko02020,map02020	M00499,M00500,M00501,M00772	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
WZS1_k127_1603194_1	1379270.AUXF01000003_gene3385	4.504e-110	386.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
WZS1_k127_1603194_3	1379270.AUXF01000007_gene919	3.356e-86	291.0	COG5587@1|root,COG5587@2|Bacteria,1ZTH8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
WZS1_k127_1603194_6	1379270.AUXF01000003_gene3372	8.454e-34	143.0	COG1188@1|root,COG1188@2|Bacteria,1ZTXI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S4 RNA-binding domain	-	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
WZS1_k127_1603194_2	1379270.AUXF01000001_gene2009	6.384e-91	314.0	COG0515@1|root,COG0515@2|Bacteria,1ZUBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_1603194_5	1379270.AUXF01000001_gene2009	1.327e-39	153.0	COG0515@1|root,COG0515@2|Bacteria,1ZUBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_1603194_4	1278073.MYSTI_04247	3.686e-57	205.0	2CZH1@1|root,32T6B@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
WZS1_k127_1603194_7	1128421.JAGA01000002_gene1772	1.158e-21	98.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
WZS1_k127_161061_4	1123278.KB893570_gene2466	2.09e-49	182.0	COG0346@1|root,COG0346@2|Bacteria,4NGE0@976|Bacteroidetes,47KJP@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
WZS1_k127_161061_2	861299.J421_2172	3.175e-65	237.0	COG0400@1|root,COG0400@2|Bacteria,1ZTXT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
WZS1_k127_161061_1	861299.J421_6143	2.111e-72	246.0	COG4032@1|root,COG4032@2|Bacteria	2|Bacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_N
WZS1_k127_161061_3	861299.J421_6144	2.044e-56	206.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
WZS1_k127_161061_5	298655.KI912267_gene6647	6.105e-41	155.0	COG3744@1|root,COG3744@2|Bacteria,2GS3K@201174|Actinobacteria,4EW60@85013|Frankiales	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WZS1_k127_161061_6	272123.Anacy_2204	2.991e-21	95.0	COG4118@1|root,COG4118@2|Bacteria,1G7T7@1117|Cyanobacteria,1HPI9@1161|Nostocales	1117|Cyanobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WZS1_k127_161061_0	761193.Runsl_2417	3.185e-114	374.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
WZS1_k127_1676888_11	1379270.AUXF01000001_gene2790	9.856e-29	119.0	COG1651@1|root,COG1651@2|Bacteria,1ZTKP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WZS1_k127_1676888_12	292459.STH2564	1.125e-17	89.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
WZS1_k127_1676888_1	1254432.SCE1572_10845	1.441e-230	729.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
WZS1_k127_1676888_0	861299.J421_4196	0.0	1026.0	COG0365@1|root,COG0365@2|Bacteria,1ZSUU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
WZS1_k127_1676888_7	1125863.JAFN01000001_gene3012	5.336e-47	181.0	COG1131@1|root,COG1131@2|Bacteria,1RGM1@1224|Proteobacteria,43ADE@68525|delta/epsilon subdivisions,2X5TA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
WZS1_k127_1676888_5	861299.J421_4191	1.755e-56	205.0	COG2386@1|root,COG2386@2|Bacteria,1ZTJ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	CcmB protein	-	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
WZS1_k127_1676888_4	861299.J421_4190	3.413e-71	248.0	COG0755@1|root,COG0755@2|Bacteria,1ZTJG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
WZS1_k127_1676888_2	861299.J421_4185	3.555e-170	544.0	COG0304@1|root,COG0304@2|Bacteria,1ZTE1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WZS1_k127_1676888_6	861299.J421_4184	6.077e-48	177.0	COG2867@1|root,COG2867@2|Bacteria,1ZTVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
WZS1_k127_1676888_9	379066.GAU_2589	2.715e-41	162.0	COG0500@1|root,COG2226@2|Bacteria,1ZTP4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS1_k127_1676888_8	1379270.AUXF01000001_gene2804	8.631e-46	170.0	COG1853@1|root,COG1853@2|Bacteria,1ZTVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WZS1_k127_1676888_3	861299.J421_4181	3.825e-89	310.0	COG0644@1|root,COG0644@2|Bacteria,1ZTEM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glucose inhibited division protein A	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
WZS1_k127_1676888_10	926569.ANT_08430	6.844e-38	152.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi	200795|Chloroflexi	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
WZS1_k127_1687963_4	1237149.C900_05550	1.781e-96	326.0	COG1506@1|root,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
WZS1_k127_1687963_7	977880.RALTA_A3179	1.105e-43	170.0	COG1752@1|root,COG1752@2|Bacteria,1REEJ@1224|Proteobacteria,2VRMU@28216|Betaproteobacteria,1K0ZP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WZS1_k127_1687963_2	555088.DealDRAFT_2852	8.436e-156	505.0	COG0076@1|root,COG0076@2|Bacteria,1TSK0@1239|Firmicutes,24A90@186801|Clostridia	186801|Clostridia	E	pyridoxal-dependent decarboxylase	ddc	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
WZS1_k127_1687963_10	1121289.JHVL01000016_gene703	5.777e-22	110.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,36FB9@31979|Clostridiaceae	186801|Clostridia	EG	DMT(Drug metabolite transporter) superfamily permease	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS1_k127_1687963_0	861299.J421_3780	0.0	1135.0	COG0178@1|root,COG0178@2|Bacteria,1ZT1W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WZS1_k127_1687963_9	448385.sce5866	1.485e-24	117.0	COG0392@1|root,COG0392@2|Bacteria,1R959@1224|Proteobacteria	1224|Proteobacteria	S	integral membrane protein	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WZS1_k127_1687963_11	314265.R2601_16040	0.0004248	49.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,2TUSB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	conserved protein, contains FHA domain	-	-	-	ko:K11894	-	-	-	-	ko00000,ko02044	3.A.23.1	-	-	FHA
WZS1_k127_1687963_6	861299.J421_3777	3.615e-83	289.0	COG0631@1|root,COG0631@2|Bacteria,1ZSYG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
WZS1_k127_1687963_8	1096546.WYO_2334	3.266e-27	129.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,1JSKK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	CO	Disulphide bond corrector protein DsbC	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
WZS1_k127_1687963_3	379066.GAU_2170	7.525e-132	437.0	COG1078@1|root,COG1078@2|Bacteria,1ZT3F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
WZS1_k127_1687963_1	1379270.AUXF01000003_gene3680	1.013e-235	742.0	COG1866@1|root,COG1866@2|Bacteria,1ZSTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
WZS1_k127_1687963_5	861299.J421_3762	3.176e-89	307.0	COG0648@1|root,COG0648@2|Bacteria,1ZSY0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
WZS1_k127_1748152_1	1415780.JPOG01000001_gene174	4.618e-79	273.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,1RWBC@1236|Gammaproteobacteria,1X339@135614|Xanthomonadales	135614|Xanthomonadales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
WZS1_k127_1748152_0	1125863.JAFN01000001_gene1711	1.825e-253	802.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WZS1_k127_1748152_2	251221.35212310	7.014e-22	101.0	COG1562@1|root,COG1562@2|Bacteria,1G078@1117|Cyanobacteria	1117|Cyanobacteria	I	Phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
WZS1_k127_1828694_3	399739.Pmen_1924	0.0002039	47.0	2DXXZ@1|root,3475N@2|Bacteria,1P2WY@1224|Proteobacteria,1ST3H@1236|Gammaproteobacteria,1YGQS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
WZS1_k127_1828694_2	861299.J421_3258	4.69e-63	225.0	COG1212@1|root,COG1212@2|Bacteria,1ZSRD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
WZS1_k127_1828694_0	861299.J421_3257	8.849e-261	823.0	COG0504@1|root,COG0504@2|Bacteria,1ZT0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WZS1_k127_1828694_1	1379270.AUXF01000006_gene266	1.976e-76	275.0	COG2877@1|root,COG2877@2|Bacteria,1ZUCD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
WZS1_k127_1831291_1	1379270.AUXF01000003_gene3564	1.153e-124	419.0	COG5492@1|root,COG5492@2|Bacteria,1ZSN6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1831291_0	861299.J421_1890	4.455e-239	769.0	COG1629@1|root,COG4771@2|Bacteria,1ZT3K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
WZS1_k127_1831291_2	861299.J421_3861	1.143e-106	353.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
WZS1_k127_1831291_6	580332.Slit_2155	1.723e-16	84.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
WZS1_k127_1831291_4	1172179.AUKV01000009_gene4529	3.466e-72	250.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
WZS1_k127_1831291_5	1304888.ATWF01000001_gene1476	3.086e-35	150.0	COG0218@1|root,COG0218@2|Bacteria,2GFRK@200930|Deferribacteres	200930|Deferribacteres	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
WZS1_k127_1831291_3	644966.Tmar_2225	1.315e-81	276.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WCCB@538999|Clostridiales incertae sedis	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WZS1_k127_1848311_3	861299.J421_2907	2.861e-30	138.0	COG5000@1|root,COG5000@2|Bacteria,1ZSZU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
WZS1_k127_1848311_2	861299.J421_2906	9.874e-41	164.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WZS1_k127_1848311_1	861299.J421_2904	5.031e-75	272.0	COG1538@1|root,COG1538@2|Bacteria,1ZSMB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WZS1_k127_1848311_0	861299.J421_2903	3.639e-119	396.0	COG0845@1|root,COG0845@2|Bacteria,1ZSX4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
WZS1_k127_1848311_4	483219.LILAB_29125	8.996e-10	67.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42NBA@68525|delta/epsilon subdivisions,2X5CS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS1_k127_1856293_0	502025.Hoch_3071	5.017e-162	552.0	COG5184@1|root,COG5184@2|Bacteria,1PG0V@1224|Proteobacteria,4356B@68525|delta/epsilon subdivisions,2WZHG@28221|Deltaproteobacteria,2Z25P@29|Myxococcales	28221|Deltaproteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1856293_2	1123320.KB889562_gene6623	6.397e-10	68.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria	201174|Actinobacteria	K	TetR Family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
WZS1_k127_1919795_3	309807.SRU_1452	3.759e-34	141.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1919795_1	379066.GAU_1033	3.068e-63	237.0	COG0747@1|root,COG0747@2|Bacteria,1ZUDG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WZS1_k127_1919795_4	879212.DespoDRAFT_03202	2.878e-26	121.0	COG0454@1|root,COG0456@2|Bacteria,1R1X0@1224|Proteobacteria,43DC3@68525|delta/epsilon subdivisions,2X8I4@28221|Deltaproteobacteria,2MPP0@213118|Desulfobacterales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS1_k127_1919795_2	1121918.ARWE01000001_gene2996	3.404e-51	195.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,42NYM@68525|delta/epsilon subdivisions,2WKTX@28221|Deltaproteobacteria,43U6N@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WZS1_k127_1919795_0	1121918.ARWE01000001_gene2997	9.924e-100	337.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,43UHD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WZS1_k127_1934907_0	861299.J421_2772	7.569e-165	527.0	COG0050@1|root,COG0050@2|Bacteria,1ZSZD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
WZS1_k127_1934907_3	1122989.KB898586_gene2420	2.369e-08	57.0	2BV3U@1|root,32QGX@2|Bacteria,4PC67@976|Bacteroidetes,2G01C@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_1934907_1	861299.J421_2757	5.826e-146	486.0	COG0215@1|root,COG0215@2|Bacteria,1ZT77@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	DALR_2	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
WZS1_k127_1934907_2	300852.55773097	1.116e-55	200.0	COG0668@1|root,COG0668@2|Bacteria,1WJII@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	mechanosensitive ion channel	-	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
WZS1_k127_1945676_1	592015.HMPREF1705_01565	6.168e-18	83.0	COG0222@1|root,COG0222@2|Bacteria,3TB80@508458|Synergistetes	508458|Synergistetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WZS1_k127_1945676_0	861299.J421_2767	0.0	1845.0	COG0085@1|root,COG0085@2|Bacteria,1ZSQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WZS1_k127_195457_0	861299.J421_5759	1.425e-123	412.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_195457_2	861299.J421_2711	5.01e-52	188.0	COG0457@1|root,COG0457@2|Bacteria,1ZTX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
WZS1_k127_195457_1	1379270.AUXF01000004_gene3094	4.514e-89	310.0	COG1022@1|root,COG1022@2|Bacteria,1ZT60@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
WZS1_k127_1982006_3	666684.AfiDRAFT_1485	4.557e-76	269.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,3JRHC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WZS1_k127_1982006_2	316274.Haur_4632	4.276e-108	364.0	COG0013@1|root,COG0013@2|Bacteria,2G6Z3@200795|Chloroflexi,37695@32061|Chloroflexia	32061|Chloroflexia	J	Threonyl alanyl tRNA synthetase SAD	-	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WZS1_k127_1982006_0	861299.J421_2347	6.116e-159	515.0	COG0531@1|root,COG0531@2|Bacteria,1ZSST@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WZS1_k127_1982006_5	118166.JH976537_gene3326	8.019e-26	116.0	COG3695@1|root,COG3695@2|Bacteria,1G82G@1117|Cyanobacteria,1HCND@1150|Oscillatoriales	1117|Cyanobacteria	L	Methylated dna-protein cysteine methyltransferase	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
WZS1_k127_1982006_1	1121104.AQXH01000001_gene1951	5.134e-114	383.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_1982006_4	96561.Dole_2535	1.086e-72	250.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,42NEJ@68525|delta/epsilon subdivisions,2WM86@28221|Deltaproteobacteria,2MJ18@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
WZS1_k127_2001444_1	398720.MED217_05317	1.572e-153	502.0	COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,1HZCZ@117743|Flavobacteriia,2XK5J@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Putative modulator of DNA gyrase	tldD3	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WZS1_k127_2001444_0	1358423.N180_00245	3.36e-239	750.0	COG0312@1|root,COG0312@2|Bacteria,4NG2Y@976|Bacteroidetes,1IRC4@117747|Sphingobacteriia	976|Bacteroidetes	S	Putative modulator of DNA gyrase	tldD1	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WZS1_k127_2032963_2	861299.J421_0464	1.56e-148	492.0	COG0793@1|root,COG0793@2|Bacteria,1ZT92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WZS1_k127_2032963_4	519989.ECTPHS_05135	5.105e-52	194.0	COG0730@1|root,COG0730@2|Bacteria,1RGCZ@1224|Proteobacteria,1S7QU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WZS1_k127_2032963_5	667121.ET1_07_00310	5.243e-12	72.0	COG5455@1|root,COG5455@2|Bacteria,1N3PU@1224|Proteobacteria,1S15B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	response to cobalt ion	cigR	-	-	-	-	-	-	-	-	-	-	-	RcnB
WZS1_k127_2032963_1	316274.Haur_3267	7.199e-162	525.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
WZS1_k127_2032963_0	1379270.AUXF01000001_gene2138	6.139e-282	878.0	COG2382@1|root,COG2382@2|Bacteria,1ZUJ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
WZS1_k127_2032963_3	861299.J421_2603	2.48e-67	234.0	COG0432@1|root,COG0432@2|Bacteria,1ZV8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
WZS1_k127_2032963_7	487521.OCU_03120	6.509e-08	60.0	COG0346@1|root,COG0346@2|Bacteria,2IG8G@201174|Actinobacteria,238WT@1762|Mycobacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WZS1_k127_2046536_1	926560.KE387023_gene2647	7.389e-24	109.0	COG0596@1|root,COG0596@2|Bacteria,1WN2Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2046536_0	234267.Acid_5940	1.294e-73	268.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_2056617_0	379066.GAU_2372	2.616e-218	694.0	COG0855@1|root,COG0855@2|Bacteria,1ZT5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WZS1_k127_2056617_1	861299.J421_2890	4.362e-125	409.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WZS1_k127_2056617_2	861299.J421_2889	4.577e-11	64.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WZS1_k127_2072760_0	861299.J421_1767	3.284e-77	269.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
WZS1_k127_2072760_1	1313304.CALK_1098	9.782e-07	58.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
WZS1_k127_2082415_0	1123399.AQVE01000022_gene386	6.433e-21	93.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,1S62I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0145 family	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WZS1_k127_2082415_1	861299.J421_2522	1.756e-12	72.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K02040,ko:K03286,ko:K21218	ko02010,ko02020,ko02040,ko05152,map02010,map02020,map02040,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	1.A.30.1,1.B.6,3.A.1.7	-	-	NMT1,OMP_b-brl,OmpA
WZS1_k127_2085221_0	1379270.AUXF01000001_gene2301	6.717e-124	409.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1ZUF5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2085221_2	1379270.AUXF01000001_gene2300	3.379e-86	295.0	29X7K@1|root,30IWU@2|Bacteria,1ZUTH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
WZS1_k127_2085221_1	1379270.AUXF01000001_gene2299	2.589e-121	395.0	COG0714@1|root,COG0714@2|Bacteria,1ZUSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WZS1_k127_2087117_0	861299.J421_3420	2.663e-204	643.0	COG0539@1|root,COG0539@2|Bacteria,1ZSKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
WZS1_k127_2087117_2	1112204.GPOL_c25830	1.043e-38	156.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4GCWB@85026|Gordoniaceae	201174|Actinobacteria	F	Cytidylate kinase	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WZS1_k127_2087117_1	861299.J421_3422	8.608e-108	363.0	COG0128@1|root,COG0128@2|Bacteria	2|Bacteria	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:0071944,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_0998,iECNA114_1301.ECNA114_0940,iECSF_1327.ECSF_0829,iPC815.YPO1390	EPSP_synthase
WZS1_k127_2087117_3	1502852.FG94_04616	8.992e-28	117.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VU99@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WZS1_k127_2094216_1	113395.AXAI01000008_gene1102	8.452e-144	467.0	COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,2U1M9@28211|Alphaproteobacteria,3JWED@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
WZS1_k127_2094216_0	172088.AUGA01000040_gene5046	4.569e-148	475.0	COG4307@1|root,COG4307@2|Bacteria,1MXES@1224|Proteobacteria,2U06R@28211|Alphaproteobacteria,3JRXQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Putative zinc-binding metallo-peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx
WZS1_k127_2094216_2	604331.AUHY01000033_gene2397	8.879e-19	93.0	COG1520@1|root,COG5492@1|root,COG1520@2|Bacteria,COG5492@2|Bacteria,1WKKN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,SBBP
WZS1_k127_2094630_0	1123073.KB899241_gene2286	5.044e-232	743.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RSGI@1236|Gammaproteobacteria,1X5MS@135614|Xanthomonadales	135614|Xanthomonadales	Q	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WZS1_k127_2094630_1	1123073.KB899241_gene2287	2.291e-148	483.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,1RN2A@1236|Gammaproteobacteria,1X7MH@135614|Xanthomonadales	135614|Xanthomonadales	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	GCV_T,GCV_T_C
WZS1_k127_2094630_2	1379270.AUXF01000004_gene3085	4.016e-98	329.0	COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WZS1_k127_2105057_6	861299.J421_2988	2.356e-20	100.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2105057_4	1379270.AUXF01000005_gene658	9.224e-52	201.0	COG0325@1|root,COG0325@2|Bacteria,1ZTJZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WZS1_k127_2105057_7	1211817.CCAT010000065_gene647	3.189e-07	59.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,36FZ8@31979|Clostridiaceae	186801|Clostridia	D	PFAM DivIVA family protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
WZS1_k127_2105057_0	861299.J421_3048	0.0	1073.0	COG0060@1|root,COG0060@2|Bacteria,1ZSKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WZS1_k127_2105057_3	861299.J421_3049	6.862e-53	194.0	COG1734@1|root,COG1734@2|Bacteria,1ZTP9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
WZS1_k127_2105057_1	379066.GAU_1403	1.193e-85	294.0	COG0564@1|root,COG0564@2|Bacteria,1ZSXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS1_k127_2105057_8	555778.Hneap_0724	0.0007654	48.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,1SYDF@1236|Gammaproteobacteria,1WXZ3@135613|Chromatiales	135613|Chromatiales	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
WZS1_k127_2105057_2	861299.J421_3054	1.091e-53	197.0	COG2204@1|root,COG2204@2|Bacteria,1ZTMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
WZS1_k127_2105057_5	243231.GSU3199	2.179e-48	188.0	COG0643@1|root,COG0643@2|Bacteria,1NW7P@1224|Proteobacteria,42PGY@68525|delta/epsilon subdivisions,2WM89@28221|Deltaproteobacteria,43T85@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	difE	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
WZS1_k127_2140766_0	330214.NIDE3501	1.142e-107	365.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
WZS1_k127_2140766_2	292564.Cyagr_2552	1.234e-53	201.0	COG1704@1|root,COG1704@2|Bacteria,1G1E8@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WZS1_k127_2140766_3	379066.GAU_3920	3.31e-25	124.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,1ZTYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
WZS1_k127_2140766_4	1040989.AWZU01000025_gene6305	1.825e-08	62.0	COG4319@1|root,COG4319@2|Bacteria,1RF3Q@1224|Proteobacteria,2U78H@28211|Alphaproteobacteria,3JZ1D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
WZS1_k127_2140766_1	247633.GP2143_18186	1.659e-74	260.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,1RPA1@1236|Gammaproteobacteria,1J9NV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
WZS1_k127_2166733_2	379066.GAU_0629	5.137e-90	300.0	COG2255@1|root,COG2255@2|Bacteria,1ZT9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WZS1_k127_2166733_1	867903.ThesuDRAFT_01678	1.576e-95	325.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3WCFH@538999|Clostridiales incertae sedis	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WZS1_k127_2166733_4	861299.J421_1752	1.805e-40	173.0	2DWGD@1|root,3407S@2|Bacteria,1ZV24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WZS1_k127_2166733_0	379066.GAU_0627	2.593e-137	446.0	COG0343@1|root,COG0343@2|Bacteria,1ZSRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WZS1_k127_2166733_6	1379270.AUXF01000004_gene3258	1.934e-16	84.0	COG1862@1|root,COG1862@2|Bacteria,1ZU5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
WZS1_k127_2166733_5	592015.HMPREF1705_00969	7.632e-40	156.0	COG0242@1|root,COG0242@2|Bacteria,3TB8D@508458|Synergistetes	508458|Synergistetes	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WZS1_k127_2166733_3	379066.GAU_0624	5.701e-48	175.0	COG0223@1|root,COG0223@2|Bacteria,1ZTE5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WZS1_k127_2170978_7	861299.J421_3615	1.341e-29	122.0	COG0848@1|root,COG0848@2|Bacteria,1ZTXP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
WZS1_k127_2170978_6	1379270.AUXF01000003_gene3846	1.063e-29	123.0	COG0848@1|root,COG0848@2|Bacteria,1ZTTP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
WZS1_k127_2170978_4	861299.J421_3617	7.803e-84	284.0	COG0811@1|root,COG0811@2|Bacteria,1ZTH1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
WZS1_k127_2170978_5	861299.J421_3618	8.22e-46	174.0	COG0810@1|root,COG0810@2|Bacteria,1ZSVC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WZS1_k127_2170978_2	861299.J421_3619	5.459e-98	337.0	COG5002@1|root,COG5002@2|Bacteria,1ZTF2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WZS1_k127_2170978_3	861299.J421_3620	4.418e-95	316.0	COG0745@1|root,COG0745@2|Bacteria,1ZT8B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS1_k127_2170978_1	861299.J421_3622	4.122e-114	385.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1ZTDZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
WZS1_k127_2170978_0	405948.SACE_6014	1.628e-123	411.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4DY9V@85010|Pseudonocardiales	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WZS1_k127_2207794_1	1379270.AUXF01000004_gene3283	7.445e-118	387.0	COG0568@1|root,COG0568@2|Bacteria,1ZSNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS1_k127_2207794_4	861299.J421_2526	2.163e-33	138.0	COG2802@1|root,COG2802@2|Bacteria,1ZUZ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
WZS1_k127_2207794_0	379066.GAU_0600	4.444e-175	560.0	COG0277@1|root,COG0277@2|Bacteria,1ZT11@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
WZS1_k127_2207794_3	269084.syc2373_d	3.156e-41	167.0	COG0277@1|root,COG0277@2|Bacteria,1G176@1117|Cyanobacteria,1GYXW@1129|Synechococcus	1117|Cyanobacteria	C	Glycolate oxidase subunit GlcE	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
WZS1_k127_2207794_2	1379270.AUXF01000004_gene3287	5.365e-42	160.0	COG0247@1|root,COG0247@2|Bacteria,1ZSTK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S binding domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG
WZS1_k127_2224704_0	1379270.AUXF01000001_gene2749	2.81e-305	948.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_2252398_4	1230460.C495_08535	1.611e-30	128.0	COG3467@1|root,arCOG00520@2157|Archaea,2Y26T@28890|Euryarchaeota,23ZHI@183963|Halobacteria	183963|Halobacteria	S	Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
WZS1_k127_2252398_1	379066.GAU_1496	1.829e-90	307.0	COG0111@1|root,COG0111@2|Bacteria,1ZUE9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
WZS1_k127_2252398_3	247490.KSU1_B0214	1.232e-56	215.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WZS1_k127_2252398_2	1379270.AUXF01000007_gene1027	1.734e-82	284.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,CarboxypepD_reg,DUF1080,F5_F8_type_C,G5,G8,Glyco_hyd_101C,Glyco_hydro_101,Trypsin_2,YSIRK_signal,fn3
WZS1_k127_2252398_0	861299.J421_4393	3.291e-275	866.0	COG1643@1|root,COG1643@2|Bacteria,1ZT2C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Helicase associated domain (HA2)  Add an annotation	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
WZS1_k127_2263275_0	1296416.JACB01000010_gene1640	6.278e-120	399.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HYZH@117743|Flavobacteriia,2YISC@290174|Aquimarina	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_2263275_1	861299.J421_4104	1.747e-86	310.0	COG5492@1|root,COG5492@2|Bacteria,1ZUE7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
WZS1_k127_2263275_2	1379270.AUXF01000001_gene2260	1.027e-53	194.0	COG2318@1|root,COG2318@2|Bacteria,1ZUV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
WZS1_k127_2263275_4	1121920.AUAU01000005_gene974	6.322e-05	51.0	COG2318@1|root,COG2318@2|Bacteria,3Y5VC@57723|Acidobacteria	57723|Acidobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_2263275_3	861299.J421_1395	8.173e-41	151.0	COG2234@1|root,COG2234@2|Bacteria,1ZSXY@142182|Gemmatimonadetes	2|Bacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WZS1_k127_2280548_8	861299.J421_3472	1.877e-20	94.0	COG0536@1|root,COG0536@2|Bacteria,1ZSVS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
WZS1_k127_2280548_4	316274.Haur_4546	6.41e-58	219.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi,37541@32061|Chloroflexia	32061|Chloroflexia	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
WZS1_k127_2280548_2	861299.J421_3470	4.899e-119	392.0	COG0635@1|root,COG0635@2|Bacteria,1ZSSU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS1_k127_2280548_3	1379270.AUXF01000006_gene61	9.097e-110	364.0	COG1420@1|root,COG1420@2|Bacteria,1ZTER@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
WZS1_k127_2280548_1	861299.J421_3468	6.374e-127	432.0	COG0484@1|root,COG0484@2|Bacteria,1ZSVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WZS1_k127_2280548_5	861299.J421_3467	9.42e-40	168.0	COG2264@1|root,COG2264@2|Bacteria,1ZST2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Met-10+ like-protein	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WZS1_k127_2280548_7	886293.Sinac_1541	1.42e-24	112.0	COG1385@1|root,COG1385@2|Bacteria,2IZRM@203682|Planctomycetes	203682|Planctomycetes	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
WZS1_k127_2280548_6	561175.KB894094_gene1632	1.357e-35	142.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria,4EJSG@85012|Streptosporangiales	201174|Actinobacteria	FG	HIT domain	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
WZS1_k127_2280548_0	1379270.AUXF01000006_gene68	5.929e-131	439.0	COG1193@1|root,COG1193@2|Bacteria,1ZSWM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WZS1_k127_228827_11	861299.J421_2881	0.0001866	50.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WZS1_k127_228827_8	1121468.AUBR01000004_gene144	1.744e-12	72.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,42GRS@68295|Thermoanaerobacterales	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
WZS1_k127_228827_3	861299.J421_2883	1.472e-66	233.0	COG0353@1|root,COG0353@2|Bacteria,1ZTJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
WZS1_k127_228827_9	1379270.AUXF01000005_gene388	5.575e-10	66.0	29142@1|root,2ZNRG@2|Bacteria,1ZV6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_228827_4	379066.GAU_1115	1.139e-52	195.0	COG2018@1|root,COG2018@2|Bacteria,1ZTK7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
WZS1_k127_228827_1	379066.GAU_1116	2.616e-119	385.0	COG1100@1|root,COG1100@2|Bacteria,1ZSQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
WZS1_k127_228827_6	1379270.AUXF01000005_gene391	4.347e-44	171.0	COG0558@1|root,COG0558@2|Bacteria,1ZSXG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WZS1_k127_228827_2	379066.GAU_1122	8.552e-114	379.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1ZSS9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
WZS1_k127_228827_7	1379270.AUXF01000005_gene394	3.122e-31	129.0	COG0576@1|root,COG0576@2|Bacteria,1ZTSJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WZS1_k127_228827_0	861299.J421_2890	3.325e-123	406.0	COG0484@1|root,COG0484@2|Bacteria,1ZT5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WZS1_k127_228827_10	195253.Syn6312_3532	2.218e-06	51.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1GYE0@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WZS1_k127_228827_5	1303518.CCALI_00492	1.124e-44	164.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WZS1_k127_2289239_1	240015.ACP_3542	1.436e-130	432.0	COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria,2JIUW@204432|Acidobacteriia	204432|Acidobacteriia	E	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_2289239_2	1379270.AUXF01000004_gene3140	1.679e-69	250.0	COG4324@1|root,COG4324@2|Bacteria,1ZT8G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
WZS1_k127_2289239_3	861299.J421_2657	6.017e-51	202.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	2|Bacteria	N	domain, Protein	-	-	3.2.1.4,3.4.17.14	ko:K01179,ko:K07260,ko:K13735	ko00500,ko00550,ko01100,ko01502,ko02020,ko05100,map00500,map00550,map01100,map01502,map02020,map05100	M00651	R06200,R11307,R11308	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	GH5,GH9	-	Big_1,Big_2,Glug,IAT_beta,Invasin_D3,LysM,Mfa_like_1,SLH
WZS1_k127_2289239_0	1089553.Tph_c09340	1.217e-301	964.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WZS1_k127_2289239_4	1379270.AUXF01000004_gene3142	4.855e-23	100.0	COG0825@1|root,COG0825@2|Bacteria,1ZSW6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
WZS1_k127_2292130_1	1047013.AQSP01000105_gene1436	1.38e-82	287.0	COG2421@1|root,COG2421@2|Bacteria,2NR72@2323|unclassified Bacteria	2|Bacteria	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
WZS1_k127_2292130_3	861299.J421_0787	6.264e-74	258.0	COG0631@1|root,COG0631@2|Bacteria,1ZSPY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
WZS1_k127_2292130_4	56110.Oscil6304_5307	7.893e-52	207.0	COG1680@1|root,COG1680@2|Bacteria,1G5M7@1117|Cyanobacteria	1117|Cyanobacteria	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WZS1_k127_2292130_0	502025.Hoch_5176	3.988e-165	542.0	COG1228@1|root,COG1228@2|Bacteria,1MY4V@1224|Proteobacteria,4383R@68525|delta/epsilon subdivisions,2X3DQ@28221|Deltaproteobacteria,2YVM1@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_2292130_2	246197.MXAN_0661	1.232e-81	278.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WZS1_k127_2292130_5	379066.GAU_3235	9.982e-30	124.0	COG2091@1|root,COG2091@2|Bacteria,1ZUGF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2324892_1	861299.J421_2624	6.635e-95	320.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS1_k127_2324892_0	357808.RoseRS_0235	0.0	1127.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,374T1@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WZS1_k127_2324892_2	404589.Anae109_3805	1.002e-24	107.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
WZS1_k127_2324892_3	861299.J421_0065	1.871e-13	80.0	COG2120@1|root,COG2120@2|Bacteria,1ZT6U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WZS1_k127_2354015_4	861299.J421_5695	1.241e-125	420.0	COG1680@1|root,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WZS1_k127_2354015_2	861299.J421_6093	1.251e-165	539.0	COG2355@1|root,COG2355@2|Bacteria,1ZU9D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WZS1_k127_2354015_3	861299.J421_6089	2.618e-140	467.0	COG1073@1|root,COG1680@1|root,COG1073@2|Bacteria,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Beta-lactamase,DUF3471,Hydrolase_4
WZS1_k127_2354015_0	861299.J421_3037	5.039e-201	636.0	COG1012@1|root,COG1012@2|Bacteria,1ZUF7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WZS1_k127_2354015_1	1396141.BATP01000059_gene2568	3.793e-171	552.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
WZS1_k127_2354015_7	278963.ATWD01000001_gene1609	0.0008657	51.0	COG4319@1|root,COG4319@2|Bacteria,3Y4YW@57723|Acidobacteria,2JJHI@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
WZS1_k127_2354015_5	861299.J421_6327	2.519e-14	81.0	299N1@1|root,2ZWQD@2|Bacteria,1ZV9Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2354015_6	1123508.JH636447_gene7821	8.879e-14	84.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
WZS1_k127_2364040_1	1379270.AUXF01000004_gene2939	1.249e-31	137.0	2EYYT@1|root,33S5J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2364040_0	945713.IALB_0608	7.843e-126	430.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
WZS1_k127_2406465_0	379066.GAU_1920	7.055e-184	616.0	COG1629@1|root,COG4771@2|Bacteria,1ZST4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	CarboxypepD_reg-like domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarboxypepD_reg,Plug,TonB_dep_Rec
WZS1_k127_2406465_1	861299.J421_3663	7.481e-184	584.0	COG1228@1|root,COG1228@2|Bacteria,1ZSU7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_2406465_3	1379270.AUXF01000001_gene2747	7.907e-41	168.0	COG1196@1|root,COG1196@2|Bacteria,1ZU2U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2406465_2	404589.Anae109_0423	7.85e-42	159.0	COG2062@1|root,COG2062@2|Bacteria,1PKQQ@1224|Proteobacteria,43AAX@68525|delta/epsilon subdivisions,2WYNV@28221|Deltaproteobacteria,2Z26S@29|Myxococcales	28221|Deltaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WZS1_k127_2411800_3	1118235.CAJH01000061_gene3416	7.249e-20	105.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,1RQ1P@1236|Gammaproteobacteria,1X5A0@135614|Xanthomonadales	135614|Xanthomonadales	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WZS1_k127_2411800_1	1242864.D187_005843	3.268e-132	435.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WINR@28221|Deltaproteobacteria,2YX29@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.55,2.6.1.77	ko:K03851,ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684,R05652	RC00006,RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
WZS1_k127_2411800_0	1242864.D187_005845	3.263e-170	544.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WZS1_k127_2411800_2	639030.JHVA01000001_gene103	2.613e-78	281.0	COG3303@1|root,COG3303@2|Bacteria,3Y9D9@57723|Acidobacteria	57723|Acidobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
WZS1_k127_2423444_3	1254432.SCE1572_01960	3.446e-45	171.0	COG1309@1|root,COG1309@2|Bacteria,1N6R3@1224|Proteobacteria,42VN1@68525|delta/epsilon subdivisions,2WRVD@28221|Deltaproteobacteria,2YVPX@29|Myxococcales	28221|Deltaproteobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
WZS1_k127_2423444_2	103733.JNYO01000027_gene2409	5.106e-49	191.0	28PB4@1|root,2ZC42@2|Bacteria,2GP5R@201174|Actinobacteria,4E1BG@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2423444_0	1163407.UU7_05698	1.88e-121	415.0	COG1228@1|root,COG1228@2|Bacteria,1R6NP@1224|Proteobacteria,1SZBD@1236|Gammaproteobacteria,1X5QW@135614|Xanthomonadales	135614|Xanthomonadales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_2423444_1	1121930.AQXG01000011_gene1720	1.293e-58	211.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WZS1_k127_243252_3	1114964.L485_19660	1.007e-56	203.0	28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,2U5RX@28211|Alphaproteobacteria,2K5KG@204457|Sphingomonadales	204457|Sphingomonadales	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
WZS1_k127_243252_1	379066.GAU_0729	4.382e-58	207.0	COG1704@1|root,COG1704@2|Bacteria,1ZTQE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WZS1_k127_243252_6	1267535.KB906767_gene2794	4.976e-16	89.0	COG1708@1|root,COG1708@2|Bacteria,3Y7NX@57723|Acidobacteria,2JNB7@204432|Acidobacteriia	204432|Acidobacteriia	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_243252_5	379066.GAU_0727	1.786e-21	106.0	COG1512@1|root,COG1512@2|Bacteria,1ZT1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
WZS1_k127_243252_4	926550.CLDAP_39250	3.331e-36	145.0	COG1651@1|root,COG1651@2|Bacteria,2G769@200795|Chloroflexi	200795|Chloroflexi	O	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WZS1_k127_243252_2	861299.J421_4004	6.54e-58	210.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WZS1_k127_243252_0	861299.J421_2641	1.881e-95	328.0	COG1519@1|root,COG1519@2|Bacteria,1ZSXB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
WZS1_k127_2436331_2	290397.Adeh_0224	8.646e-31	130.0	COG3568@1|root,COG3568@2|Bacteria,1N29G@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WZS1_k127_2436331_1	861299.J421_3051	2.179e-35	143.0	COG0597@1|root,COG0597@2|Bacteria,1ZTVD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WZS1_k127_2436331_0	331869.BAL199_10155	8.191e-107	356.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,4BQ5Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
WZS1_k127_2470417_1	234267.Acid_3281	1.564e-56	205.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
WZS1_k127_2470417_6	379066.GAU_3582	0.0009509	49.0	2AF07@1|root,314YA@2|Bacteria,1ZV17@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2470417_5	1279017.AQYJ01000026_gene22	4.89e-05	46.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2470417_2	1415630.U771_18980	1.567e-41	163.0	COG1376@1|root,COG1376@2|Bacteria,1RA7Q@1224|Proteobacteria,1RSIE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
WZS1_k127_2470417_3	1437824.BN940_01586	8.039e-41	173.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VK0M@28216|Betaproteobacteria,3T28S@506|Alcaligenaceae	28216|Betaproteobacteria	P	COG4771 Outer membrane receptor for ferrienterochelin and colicins	-	-	-	ko:K02014,ko:K16087,ko:K16089	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.1,1.B.14.10,1.B.14.2	-	-	Plug,TonB_dep_Rec
WZS1_k127_2470417_0	379066.GAU_2230	8.169e-67	237.0	COG2197@1|root,COG2197@2|Bacteria,1ZTJ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS1_k127_2470417_4	1463857.JOFZ01000004_gene2813	1.536e-06	51.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WZS1_k127_2477329_9	861299.J421_0460	6.836e-20	92.0	COG1807@1|root,COG1807@2|Bacteria,1ZUFB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WZS1_k127_2477329_4	760192.Halhy_4780	4.492e-132	433.0	COG0477@1|root,COG2814@2|Bacteria,4NFM7@976|Bacteroidetes,1INXG@117747|Sphingobacteriia	976|Bacteroidetes	EGP	major facilitator superfamily	tetA	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
WZS1_k127_2477329_2	379066.GAU_3212	3.275e-152	496.0	COG0006@1|root,COG0006@2|Bacteria,1ZUGP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WZS1_k127_2477329_0	215803.DB30_7073	1.765e-227	712.0	COG1509@1|root,COG1509@2|Bacteria,1R8HT@1224|Proteobacteria,43DMX@68525|delta/epsilon subdivisions,2X6DS@28221|Deltaproteobacteria,2YUSV@29|Myxococcales	28221|Deltaproteobacteria	E	lysine 2,3-aminomutase	kamA1	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	LAM_C
WZS1_k127_2477329_5	391735.Veis_2479	1.146e-99	336.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,2VN89@28216|Betaproteobacteria,4AH50@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
WZS1_k127_2477329_3	693977.Deipr_2519	1.52e-141	460.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	ycsG	-	-	-	-	-	-	-	-	-	-	-	Nramp
WZS1_k127_2477329_7	1379270.AUXF01000004_gene3009	4.664e-56	202.0	COG2318@1|root,COG2318@2|Bacteria,1ZU3G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_2477329_6	876044.IMCC3088_1921	2.221e-61	215.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S3RP@1236|Gammaproteobacteria,1J65B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WZS1_k127_2477329_1	502025.Hoch_0274	4.937e-221	708.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions,2WKXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
WZS1_k127_2477329_8	234267.Acid_1582	7.92e-46	170.0	COG2936@1|root,COG2936@2|Bacteria,3Y684@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_2495198_0	1122176.KB903558_gene4168	4.983e-82	285.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1IQKU@117747|Sphingobacteriia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WZS1_k127_2495198_5	379066.GAU_2847	6.485e-38	160.0	2ARQH@1|root,31H1J@2|Bacteria,1ZUJU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
WZS1_k127_2495198_1	1379270.AUXF01000002_gene1600	3.775e-79	274.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1600|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2495198_4	1379270.AUXF01000001_gene2273	6.663e-49	189.0	COG1285@1|root,COG1285@2|Bacteria,1ZUVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
WZS1_k127_2495198_2	709986.Deima_0279	8.728e-71	263.0	COG1409@1|root,COG1409@2|Bacteria,1WINK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WZS1_k127_2495198_3	404589.Anae109_3731	4.604e-61	222.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
WZS1_k127_2513559_1	1123368.AUIS01000019_gene1214	3.84e-173	568.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WZS1_k127_2513559_0	1123368.AUIS01000019_gene1214	1.835e-212	689.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,1RNCM@1236|Gammaproteobacteria,2NE5Q@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WZS1_k127_2513559_2	1123368.AUIS01000019_gene1213	7.411e-68	235.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,1S40Y@1236|Gammaproteobacteria,2NCY9@225057|Acidithiobacillales	225057|Acidithiobacillales	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WZS1_k127_2513559_4	953739.SVEN_7222	6.369e-36	158.0	COG4412@1|root,COG4412@2|Bacteria,2GMKQ@201174|Actinobacteria	201174|Actinobacteria	M	PFAM peptidase M6, immune inhibitor A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
WZS1_k127_2513559_3	1191523.MROS_2748	1.049e-36	142.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS1_k127_2557331_3	861299.J421_0470	2.366e-45	170.0	COG0515@1|root,COG0515@2|Bacteria,1ZURQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_2557331_1	936136.ARRT01000006_gene3220	3.717e-55	201.0	COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2U99X@28211|Alphaproteobacteria,4BEGN@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
WZS1_k127_2557331_0	937777.Deipe_2643	1.845e-181	582.0	COG0513@1|root,COG0513@2|Bacteria,1WKZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WZS1_k127_2557331_2	1237149.C900_00291	9.285e-47	172.0	2CHCP@1|root,32S5R@2|Bacteria,4NS9G@976|Bacteroidetes,47RF4@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WZS1_k127_2557331_4	761193.Runsl_0116	3.621e-41	156.0	COG2335@1|root,COG2335@2|Bacteria,4NMPI@976|Bacteroidetes,47XS3@768503|Cytophagia	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
WZS1_k127_2589039_2	1313421.JHBV01000020_gene5217	9.366e-115	381.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
WZS1_k127_2589039_3	935863.AWZR01000007_gene217	6.127e-38	150.0	COG1595@1|root,COG1595@2|Bacteria,1QDHS@1224|Proteobacteria,1SS07@1236|Gammaproteobacteria,1X6DE@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS1_k127_2589039_4	1123073.KB899241_gene1794	1.354e-23	112.0	COG0265@1|root,COG0265@2|Bacteria,1PCJA@1224|Proteobacteria,1SXM8@1236|Gammaproteobacteria,1X6DM@135614|Xanthomonadales	135614|Xanthomonadales	O	PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
WZS1_k127_2589039_7	379066.GAU_2648	6.138e-12	78.0	COG5349@1|root,COG5349@2|Bacteria,1ZU3C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
WZS1_k127_2589039_6	404380.Gbem_1194	2.763e-15	88.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,42UMQ@68525|delta/epsilon subdivisions,2WQY1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
WZS1_k127_2589039_5	379066.GAU_0167	2.2e-20	94.0	COG2924@1|root,COG2924@2|Bacteria,1ZTWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
WZS1_k127_2589039_8	861299.J421_4475	1.559e-06	53.0	2CA9X@1|root,2ZJY8@2|Bacteria,1ZU1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2589039_1	404589.Anae109_0005	7.889e-122	400.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WZS1_k127_2589039_0	215803.DB30_3561	4.983e-124	416.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWSR@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS1_k127_2589039_9	378806.STAUR_2941	0.0005415	48.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42U6K@68525|delta/epsilon subdivisions,2WQ4K@28221|Deltaproteobacteria,2YZCG@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
WZS1_k127_259343_0	518766.Rmar_1231	7.26e-221	697.0	COG1012@1|root,COG1012@2|Bacteria,4NFTW@976|Bacteroidetes,1FIW6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Aldehyde dehydrogenase family	pruA	-	1.2.1.88,1.5.5.2	ko:K00294,ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
WZS1_k127_259343_1	861299.J421_3781	7.421e-71	262.0	COG0725@1|root,COG0725@2|Bacteria	2|Bacteria	P	tungstate binding	wtpA	-	-	ko:K15495	ko02010,map02010	M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.5	-	-	SBP_bac_11
WZS1_k127_259343_2	1463879.JOHP01000102_gene2545	5.599e-27	113.0	COG1324@1|root,COG1324@2|Bacteria,2IQF1@201174|Actinobacteria	201174|Actinobacteria	P	Divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
WZS1_k127_259343_4	68260.JOAY01000063_gene253	0.0007529	46.0	COG0454@1|root,COG0454@2|Bacteria,2I32U@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WZS1_k127_2595135_5	1379270.AUXF01000005_gene830	6.517e-16	89.0	2FIMZ@1|root,34ADU@2|Bacteria,1ZTYV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2595135_4	379066.GAU_1563	9.824e-41	160.0	COG0251@1|root,COG0251@2|Bacteria,1ZTSF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WZS1_k127_2595135_0	626939.HMPREF9443_00167	2.201e-215	682.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4H1XW@909932|Negativicutes	909932|Negativicutes	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WZS1_k127_2595135_2	861299.J421_3194	4.244e-66	235.0	COG0084@1|root,COG0084@2|Bacteria,1ZST0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WZS1_k127_2595135_3	1249627.D779_0229	1.722e-63	229.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,1RNTY@1236|Gammaproteobacteria,1WX0P@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WZS1_k127_2595135_1	861299.J421_3192	9.415e-98	326.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WZS1_k127_2613278_2	861299.J421_3385	6.138e-126	410.0	COG0042@1|root,COG0042@2|Bacteria,1ZSQC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
WZS1_k127_2613278_6	861299.J421_3384	1.031e-62	231.0	COG1691@1|root,COG1691@2|Bacteria	2|Bacteria	C	(AIR) carboxylase	cpmA	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
WZS1_k127_2613278_5	635013.TherJR_1274	3.956e-63	239.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,261JI@186807|Peptococcaceae	186801|Clostridia	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WZS1_k127_2613278_7	765910.MARPU_02530	1.738e-29	134.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1T2D4@1236|Gammaproteobacteria,1WWB6@135613|Chromatiales	135613|Chromatiales	PT	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS
WZS1_k127_2613278_1	1123368.AUIS01000029_gene1282	2.461e-132	434.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,1RQEI@1236|Gammaproteobacteria,2NBXD@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
WZS1_k127_2613278_3	1123368.AUIS01000029_gene1283	1.542e-67	235.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,2NCU3@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WZS1_k127_2613278_0	1379270.AUXF01000006_gene151	0.0	1071.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1ZU89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WZS1_k127_2613278_4	861299.J421_3381	2.345e-63	221.0	COG0034@1|root,COG0034@2|Bacteria,1ZTD7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6
WZS1_k127_2619274_10	290397.Adeh_0418	1.503e-13	75.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
WZS1_k127_2619274_11	714943.Mucpa_6450	2.564e-09	66.0	2EAQW@1|root,334T4@2|Bacteria,4NWX2@976|Bacteroidetes,1IUAR@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2619274_1	861299.J421_0749	7.369e-142	468.0	COG0624@1|root,COG0624@2|Bacteria,1ZTCV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS1_k127_2619274_9	1519464.HY22_12165	1.702e-34	136.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WZS1_k127_2619274_7	435908.IDSA_02890	3.874e-75	276.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,2QFFF@267893|Idiomarinaceae	1236|Gammaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	iECED1_1282.ECED1_1467,iECP_1309.ECP_1308	Trp_syntA
WZS1_k127_2619274_0	1254432.SCE1572_07860	4.94e-174	554.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,2YU86@29|Myxococcales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS1_k127_2619274_3	595494.Tola_0941	2.775e-130	434.0	COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,1Y3UQ@135624|Aeromonadales	135624|Aeromonadales	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
WZS1_k127_2619274_6	448385.sce1100	1.975e-116	395.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria,2YUVG@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	Glycos_trans_3N,Glycos_transf_3
WZS1_k127_2619274_8	1517681.HW45_16550	5.207e-51	205.0	COG0512@1|root,COG0512@2|Bacteria,1RAKJ@1224|Proteobacteria,1RREB@1236|Gammaproteobacteria,1XTCZ@135623|Vibrionales	135623|Vibrionales	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	trpG	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WZS1_k127_2619274_4	1121878.AUGL01000023_gene3558	4.138e-126	422.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_1603	Anth_synt_I_N,Chorismate_bind
WZS1_k127_2619274_2	1190606.AJYG01000077_gene4139	4.447e-135	439.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,1S11K@1236|Gammaproteobacteria,1XVN4@135623|Vibrionales	135623|Vibrionales	E	NeuB family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WZS1_k127_2619274_5	1242864.D187_005040	2.59e-119	392.0	COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria,42YS3@68525|delta/epsilon subdivisions,2WU59@28221|Deltaproteobacteria,2YTT1@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WZS1_k127_2625650_7	1379270.AUXF01000003_gene3692	1.264e-15	78.0	COG1940@1|root,COG1940@2|Bacteria,1ZT66@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WZS1_k127_2625650_2	861299.J421_3754	3.058e-95	325.0	COG0524@1|root,COG0524@2|Bacteria,1ZTFD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2625650_1	1379270.AUXF01000003_gene3690	7.755e-96	325.0	COG0643@1|root,COG0643@2|Bacteria,1ZSPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NT	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2625650_6	861299.J421_3756	2.508e-17	95.0	2EFCU@1|root,3395Q@2|Bacteria,1ZTVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2625650_0	861299.J421_3758	9.258e-148	486.0	COG0626@1|root,COG0626@2|Bacteria,1ZUSY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
WZS1_k127_2625650_3	379066.GAU_2160	2.767e-80	273.0	COG2884@1|root,COG2884@2|Bacteria,1ZTHQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	ABC transporter	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WZS1_k127_2625650_4	379066.GAU_2161	3.897e-62	244.0	COG2177@1|root,COG2177@2|Bacteria,1ZTDR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Part of the ABC transporter FtsEX involved in	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
WZS1_k127_2625650_5	861299.J421_3761	1.702e-33	139.0	COG4942@1|root,COG4942@2|Bacteria,1ZSU6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WZS1_k127_2631017_6	290397.Adeh_3306	2.788e-22	100.0	COG4911@1|root,COG4911@2|Bacteria,1QCSX@1224|Proteobacteria,4387P@68525|delta/epsilon subdivisions,2X3HG@28221|Deltaproteobacteria,2YW4D@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
WZS1_k127_2631017_2	379066.GAU_0824	1.051e-73	258.0	COG1194@1|root,COG1194@2|Bacteria,1ZTNM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	FES	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WZS1_k127_2631017_4	861299.J421_4164	1.621e-53	199.0	COG0767@1|root,COG0767@2|Bacteria,1ZSUC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WZS1_k127_2631017_3	379066.GAU_0711	1.598e-67	241.0	COG1127@1|root,COG1127@2|Bacteria,1ZT5N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WZS1_k127_2631017_5	379066.GAU_2575	4.962e-32	138.0	COG1463@1|root,COG1463@2|Bacteria,1ZTI5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
WZS1_k127_2631017_0	414684.RC1_1743	2.189e-264	833.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2JPNR@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
WZS1_k127_2631017_1	414684.RC1_1744	1.495e-189	598.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2JQCM@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS1_k127_2635919_1	861299.J421_3400	1.708e-78	269.0	COG0612@1|root,COG0612@2|Bacteria,1ZSPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS1_k127_2635919_0	379066.GAU_1764	1.014e-286	896.0	COG1185@1|root,COG1185@2|Bacteria,1ZT7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WZS1_k127_2635919_3	1379270.AUXF01000006_gene129	2.358e-33	132.0	COG0184@1|root,COG0184@2|Bacteria,1ZU0C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WZS1_k127_2635919_2	522306.CAP2UW1_2869	7.193e-72	261.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,1KQ8B@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
WZS1_k127_2641098_0	379066.GAU_2797	5e-324	1006.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,1ZT89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WZS1_k127_2641098_2	1304877.KI519399_gene4632	5.642e-37	146.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria,3JV7C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	MaoC like domain	MA20_27445	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
WZS1_k127_2641098_1	1280944.HY17_18440	7.463e-51	196.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,43X4S@69657|Hyphomonadaceae	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
WZS1_k127_2684591_0	861299.J421_4450	8.625e-319	994.0	COG0466@1|root,COG0466@2|Bacteria,1ZTCH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS1_k127_2684591_1	861299.J421_4449	2.797e-112	387.0	COG0515@1|root,COG0515@2|Bacteria,1ZTFJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_2684591_2	1237500.ANBA01000003_gene4784	4.008e-55	205.0	COG2227@1|root,COG2227@2|Bacteria,2IPID@201174|Actinobacteria	201174|Actinobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
WZS1_k127_2690273_3	479435.Kfla_0725	3.245e-05	53.0	COG3369@1|root,COG3369@2|Bacteria,2GUHK@201174|Actinobacteria	201174|Actinobacteria	S	Identified by match to SM00705 CDGSH-type zinc finger domain. Zinc finger (Znf) domains are relatively small protein motifs that bind one or more zinc atoms, and which usually contain multiple finger-like protrusions that make tandem contacts with their target molecule. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis, however they are now recognised to bind DNA, RNA, protein and or lipid substrates. The CDGSH-type zinc finger contains a CDGSH sequence motif (although the Ser residue can also be an Ala or Thr), and is found in proteins from a wide range of organisms with the exception of fungi. Proteins carrying this domain include ferredoxin-dependent glutamate synthase. CDGSH-type domains are also found in the iron-containing outer membrane protein mitoNEET. MitoNEET contains the conserved sequence C-X-C-X2-(S T)-X3-P-X-C-D-G-(S A T)-H, a defining feature of CDGSH domains, and is likely involved in iron binding rather than zinc binding	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
WZS1_k127_2690273_1	1379270.AUXF01000002_gene1184	2.45e-105	351.0	COG5504@1|root,COG5504@2|Bacteria,1ZTCN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2690273_2	194439.CT2221	1.981e-09	68.0	COG0705@1|root,COG0705@2|Bacteria,1FDF1@1090|Chlorobi	1090|Chlorobi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WZS1_k127_2690273_0	471852.Tcur_3455	1.591e-106	353.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,4EI19@85012|Streptosporangiales	201174|Actinobacteria	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WZS1_k127_2705891_5	715226.ABI_11710	0.0006696	53.0	COG0823@1|root,COG0823@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Periplasmic component of the Tol biopolymer transport system	tolB2	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WZS1_k127_2705891_0	1047013.AQSP01000131_gene1836	5.637e-118	394.0	COG2204@1|root,COG2204@2|Bacteria,2NNWS@2323|unclassified Bacteria	2|Bacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	bamW	-	-	ko:K07712,ko:K07714	ko02020,map02020	M00497,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WZS1_k127_2705891_3	448385.sce7929	3.177e-35	153.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2YUZA@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
WZS1_k127_2705891_4	596151.DesfrDRAFT_2011	4.859e-07	63.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,42Z62@68525|delta/epsilon subdivisions,2WU3Z@28221|Deltaproteobacteria,2MGJY@213115|Desulfovibrionales	28221|Deltaproteobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_2705891_1	1125863.JAFN01000001_gene1446	1.631e-116	392.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WZS1_k127_2705891_2	448385.sce7929	1.992e-48	193.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2YUZA@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
WZS1_k127_2707380_1	886293.Sinac_5754	9.17e-29	118.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS1_k127_2707380_3	246197.MXAN_7362	0.000408	52.0	COG0745@1|root,COG2199@1|root,COG2204@1|root,COG0745@2|Bacteria,COG2204@2|Bacteria,COG3706@2|Bacteria,1MXBG@1224|Proteobacteria,42NGW@68525|delta/epsilon subdivisions,2X7CV@28221|Deltaproteobacteria,2YUZ7@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
WZS1_k127_2707380_2	588932.JHOF01000018_gene1037	6.864e-10	68.0	COG1378@1|root,COG1378@2|Bacteria,1N9ZU@1224|Proteobacteria,2U7Z9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
WZS1_k127_2707380_0	379066.GAU_2771	6.17e-51	195.0	2EW3S@1|root,33PH0@2|Bacteria,1ZTQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2710693_4	1121413.JMKT01000011_gene2302	4.018e-10	67.0	COG3271@1|root,COG3271@2|Bacteria,1Q1Q5@1224|Proteobacteria,42U5R@68525|delta/epsilon subdivisions,2WQE7@28221|Deltaproteobacteria,2MGN7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39
WZS1_k127_2710693_1	861299.J421_2327	2.7e-64	230.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
WZS1_k127_2710693_3	525897.Dbac_2184	8.874e-12	66.0	COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria,42XTD@68525|delta/epsilon subdivisions,2WT90@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
WZS1_k127_2710693_2	861299.J421_2495	8.539e-62	226.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
WZS1_k127_2710693_0	358681.BBR47_20180	4.386e-137	464.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,4HC37@91061|Bacilli,26TMF@186822|Paenibacillaceae	91061|Bacilli	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_2731320_3	518766.Rmar_0272	3.087e-88	295.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
WZS1_k127_2731320_0	1268068.PG5_65010	6.393e-218	696.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	exaA	-	1.1.2.8,1.1.5.5,1.1.9.1	ko:K00114,ko:K17760,ko:K22473	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285,R09479	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2,PQQ_3
WZS1_k127_2731320_10	243231.GSU0224	4.645e-32	128.0	COG1917@1|root,COG1917@2|Bacteria,1RJX2@1224|Proteobacteria,42TVK@68525|delta/epsilon subdivisions,2WQ2T@28221|Deltaproteobacteria,43SQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WZS1_k127_2731320_5	1121920.AUAU01000010_gene126	7.582e-77	272.0	28PU4@1|root,2ZCF6@2|Bacteria	2|Bacteria	-	-	nrfJ	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2731320_12	675635.Psed_5545	1.895e-17	88.0	COG3631@1|root,COG3631@2|Bacteria,2IQ9X@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WZS1_k127_2731320_6	1163617.SCD_n02575	3e-68	233.0	2E4PM@1|root,32P93@2|Bacteria,1N4SK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2731320_4	1255043.TVNIR_0447	3.22e-88	294.0	COG1309@1|root,COG1309@2|Bacteria,1RA4T@1224|Proteobacteria,1RNQH@1236|Gammaproteobacteria,1X1EI@135613|Chromatiales	135613|Chromatiales	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
WZS1_k127_2731320_7	1227739.Hsw_2165	4.167e-63	227.0	COG2318@1|root,COG2318@2|Bacteria,4NKB3@976|Bacteroidetes,47NHI@768503|Cytophagia	976|Bacteroidetes	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
WZS1_k127_2731320_1	1379270.AUXF01000001_gene2279	2.426e-147	476.0	COG1064@1|root,COG1064@2|Bacteria,1ZSTS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Zinc-binding dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
WZS1_k127_2731320_9	794903.OPIT5_24070	1.893e-48	179.0	COG0783@1|root,COG0783@2|Bacteria,46VAF@74201|Verrucomicrobia,3K84T@414999|Opitutae	414999|Opitutae	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
WZS1_k127_2731320_2	1379270.AUXF01000005_gene642	2e-129	442.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_2731320_8	595537.Varpa_0888	2.442e-55	200.0	COG0662@1|root,COG0662@2|Bacteria,1RHWU@1224|Proteobacteria,2VT6E@28216|Betaproteobacteria,4AFMC@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WZS1_k127_2731320_11	888832.HMPREF9420_2107	1.479e-23	107.0	COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,2FT8J@200643|Bacteroidia	976|Bacteroidetes	J	endoribonuclease L-PSP	ridA	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WZS1_k127_2758429_2	1379270.AUXF01000007_gene994	4.15e-92	330.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000007_gene994|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2758429_3	861299.J421_2228	6.281e-38	154.0	COG0702@1|root,COG0702@2|Bacteria,1ZV6Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
WZS1_k127_2758429_1	477641.MODMU_4191	1.503e-94	340.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4EV6E@85013|Frankiales	201174|Actinobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
WZS1_k127_2758429_0	234267.Acid_4956	1.271e-179	574.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WZS1_k127_2763403_3	525897.Dbac_1746	7.716e-26	122.0	COG4641@1|root,COG4641@2|Bacteria,1R64N@1224|Proteobacteria,42N73@68525|delta/epsilon subdivisions,2WM84@28221|Deltaproteobacteria,2M7XA@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
WZS1_k127_2763403_0	861299.J421_2583	3.053e-132	459.0	COG1132@1|root,COG1132@2|Bacteria,1ZT2T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
WZS1_k127_2763403_1	1125863.JAFN01000001_gene536	2.155e-52	198.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
WZS1_k127_2763403_2	517417.Cpar_0525	7.833e-49	177.0	COG0217@1|root,COG0217@2|Bacteria,1FDKV@1090|Chlorobi	1090|Chlorobi	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WZS1_k127_2773644_1	861299.J421_3142	8.08e-151	480.0	COG0540@1|root,COG0540@2|Bacteria,1ZSN7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WZS1_k127_2773644_0	861299.J421_3143	3.428e-192	609.0	COG0044@1|root,COG0044@2|Bacteria,1ZT4U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WZS1_k127_2773644_7	861299.J421_3144	1.274e-15	88.0	COG1196@1|root,COG1196@2|Bacteria,1ZU4J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2773644_8	530564.Psta_4646	3.834e-05	49.0	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WZS1_k127_2773644_6	1382304.JNIL01000001_gene339	1.045e-30	131.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,4HA6Q@91061|Bacilli,279W3@186823|Alicyclobacillaceae	91061|Bacilli	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WZS1_k127_2773644_4	379066.GAU_1522	9.045e-65	226.0	COG1386@1|root,COG1386@2|Bacteria,1ZTIA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WZS1_k127_2773644_5	309801.trd_0437	4.32e-61	226.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi,27XQ1@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS1_k127_2773644_2	861299.J421_3150	3.173e-136	444.0	COG0714@1|root,COG0714@2|Bacteria,1ZT94@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WZS1_k127_2773644_3	379066.GAU_1525	1.212e-74	260.0	COG1721@1|root,COG1721@2|Bacteria,1ZSKR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WZS1_k127_2808499_1	1379270.AUXF01000007_gene1018	2.347e-292	928.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,1ZUBH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WZS1_k127_2808499_3	1122185.N792_09155	4.96e-48	178.0	COG1522@1|root,COG1522@2|Bacteria,1RJK0@1224|Proteobacteria,1S6HD@1236|Gammaproteobacteria,1X6QR@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
WZS1_k127_2808499_2	1121920.AUAU01000004_gene886	3.885e-153	493.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria	57723|Acidobacteria	E	Cys Met metabolism	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
WZS1_k127_2808499_0	861299.J421_3607	2.198e-295	921.0	COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,1ZSQV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
WZS1_k127_2808499_4	401053.AciPR4_3950	7.743e-21	94.0	COG0071@1|root,COG0071@2|Bacteria,3Y4TM@57723|Acidobacteria,2JJFI@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WZS1_k127_283602_3	379066.GAU_3584	6.884e-29	119.0	COG0836@1|root,COG0836@2|Bacteria,1ZSWG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WZS1_k127_283602_6	1379270.AUXF01000005_gene807	7.594e-07	58.0	COG2018@1|root,COG2018@2|Bacteria,1ZU1J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
WZS1_k127_283602_4	1379270.AUXF01000005_gene808	1.602e-16	88.0	2FES0@1|root,346R1@2|Bacteria,1ZU3X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_283602_1	861299.J421_3175	6.74e-157	505.0	COG0172@1|root,COG0172@2|Bacteria,1ZT0V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WZS1_k127_283602_0	379066.GAU_1545	4.318e-221	711.0	COG0210@1|root,COG0210@2|Bacteria,1ZTD5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WZS1_k127_283602_5	1379270.AUXF01000005_gene812	8.6e-09	61.0	COG0721@1|root,COG0721@2|Bacteria,1ZU4T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WZS1_k127_283602_2	861299.J421_3179	7.446e-130	432.0	COG0154@1|root,COG0154@2|Bacteria,1ZT24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS1_k127_2836193_3	861299.J421_4333	5.564e-07	55.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
WZS1_k127_2836193_2	869210.Marky_1073	9.808e-27	120.0	COG1752@1|root,COG1752@2|Bacteria,1WI5Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WZS1_k127_2836193_1	1125863.JAFN01000001_gene880	1.292e-31	128.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WZS1_k127_2836193_0	316274.Haur_4289	6.116e-202	644.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G7JV@200795|Chloroflexi,375WH@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WZS1_k127_2844327_8	1346330.M472_14980	1.804e-25	113.0	COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,1IPRA@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS1_k127_2844327_1	1379270.AUXF01000001_gene1945	1.49e-203	643.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	2|Bacteria	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS1_k127_2844327_7	761193.Runsl_0557	1.375e-52	200.0	COG0823@1|root,COG1680@1|root,COG0823@2|Bacteria,COG1680@2|Bacteria,4NHJN@976|Bacteroidetes,47JBV@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_2844327_9	113395.AXAI01000002_gene5523	4.44e-21	98.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,3K2BJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CG	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
WZS1_k127_2844327_4	1191523.MROS_0148	4.355e-86	299.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	MtrB_PioB,OMP_b-brl,OMP_b-brl_2
WZS1_k127_2844327_6	861299.J421_3932	8.287e-76	274.0	28P8D@1|root,33QB6@2|Bacteria,1ZSQK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	SusD family	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD_RagB
WZS1_k127_2844327_0	1379270.AUXF01000003_gene3454	6.206e-211	689.0	COG1629@1|root,COG4771@2|Bacteria,1ZT9M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WZS1_k127_2844327_3	861299.J421_6094	1.442e-104	354.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Beta-lactamase,Peptidase_M15
WZS1_k127_2844327_2	861299.J421_4001	8.708e-128	419.0	COG3616@1|root,COG3616@2|Bacteria,1ZSM9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
WZS1_k127_2844327_5	661478.OP10G_1553	1.999e-83	298.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_2866023_1	1379270.AUXF01000005_gene838	3.591e-69	239.0	COG0689@1|root,COG0689@2|Bacteria,1ZSYT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
WZS1_k127_2866023_2	1379270.AUXF01000005_gene837	4.2e-46	177.0	COG0615@1|root,COG0615@2|Bacteria,1ZTPI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
WZS1_k127_2866023_5	331678.Cphamn1_2004	1.716e-07	61.0	29GCI@1|root,303AD@2|Bacteria,1FE3Q@1090|Chlorobi	1090|Chlorobi	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
WZS1_k127_2866023_6	379066.GAU_1568	5.921e-05	54.0	2F5A9@1|root,33XWF@2|Bacteria,1ZTU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2866023_4	861299.J421_3199	8.915e-32	130.0	COG0824@1|root,COG0824@2|Bacteria,1ZTY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
WZS1_k127_2866023_3	861299.J421_3198	1.008e-37	155.0	COG2908@1|root,COG2908@2|Bacteria,1ZTNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
WZS1_k127_2866023_0	861299.J421_3197	6.47e-90	304.0	COG0796@1|root,COG0796@2|Bacteria,1ZUQ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WZS1_k127_2880978_1	1121106.JQKB01000058_gene5410	5.669e-11	73.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2U3WV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIGRFAM YihY family protein (not ribonuclease BN)	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WZS1_k127_2880978_0	861299.J421_2881	5.086e-146	491.0	COG2812@1|root,COG2812@2|Bacteria,1ZTFV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WZS1_k127_2891431_2	404589.Anae109_2532	1.943e-16	79.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2Z1SJ@29|Myxococcales	28221|Deltaproteobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WZS1_k127_2891431_3	1379270.AUXF01000007_gene1072	8.929e-12	78.0	2AETK@1|root,314QP@2|Bacteria,1ZU8P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2891431_1	1089550.ATTH01000001_gene1532	5.102e-38	158.0	COG1462@1|root,COG1462@2|Bacteria	2|Bacteria	M	curli production assembly transport component CsgG	-	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	CsgG,FlgT_C
WZS1_k127_2891431_0	156889.Mmc1_3378	4.407e-39	159.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_2,Sugar_tr
WZS1_k127_2950559_0	861299.J421_0487	1.085e-261	814.0	COG2936@1|root,COG2936@2|Bacteria,1ZUE2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_2950559_1	1049564.TevJSym_bb00050	3.819e-231	733.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WZS1_k127_2963307_6	234267.Acid_1835	4.217e-06	51.0	COG0531@1|root,COG0531@2|Bacteria,3Y4PR@57723|Acidobacteria	57723|Acidobacteria	E	PFAM amino acid permease-associated region	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
WZS1_k127_2963307_0	861299.J421_1402	1.953e-273	865.0	COG2091@1|root,COG2091@2|Bacteria,1ZUPU@142182|Gemmatimonadetes	2|Bacteria	H	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WZS1_k127_2963307_2	937777.Deipe_1812	9.555e-34	133.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
WZS1_k127_2963307_1	997296.PB1_11764	1.298e-58	209.0	COG2353@1|root,COG2353@2|Bacteria,1V1NX@1239|Firmicutes,4HFXF@91061|Bacilli,1ZCU9@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WZS1_k127_2963307_4	273526.SMDB11_2380	2.47e-30	129.0	COG2259@1|root,COG2259@2|Bacteria,1MZC7@1224|Proteobacteria,1SANJ@1236|Gammaproteobacteria,403SD@613|Serratia	1236|Gammaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
WZS1_k127_2963307_5	1177181.T9A_01883	2.845e-15	83.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,1SF0T@1236|Gammaproteobacteria,1XMIJ@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WZS1_k127_2963307_3	384765.SIAM614_19276	4.183e-33	129.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the pirin family	yhhW	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WZS1_k127_2977696_6	426117.M446_1694	0.000703	42.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,1JTX6@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	dppF	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678	-	ko:K12372	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WZS1_k127_2977696_0	1382306.JNIM01000001_gene876	9.183e-93	313.0	COG0384@1|root,COG0384@2|Bacteria,2G7RE@200795|Chloroflexi	200795|Chloroflexi	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
WZS1_k127_2977696_2	1096546.WYO_3494	1.068e-78	275.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TU0N@28211|Alphaproteobacteria,1JSI3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	MA20_23565	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WZS1_k127_2977696_5	1379270.AUXF01000004_gene2925	4.661e-38	146.0	COG1846@1|root,COG1846@2|Bacteria,1ZU3J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
WZS1_k127_2977696_4	1267535.KB906767_gene2393	9.523e-54	196.0	COG3127@1|root,COG3127@2|Bacteria,3Y7ZT@57723|Acidobacteria	57723|Acidobacteria	Q	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2977696_3	861299.J421_1823	6.447e-75	269.0	28P8D@1|root,2ZC2C@2|Bacteria,1ZUEX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_2977696_1	1249997.JHZW01000002_gene1837	6.529e-79	274.0	COG1629@1|root,COG4771@2|Bacteria,4NI6M@976|Bacteroidetes,1IIIH@117743|Flavobacteriia	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WZS1_k127_2999303_3	391625.PPSIR1_16930	3.083e-11	65.0	2EQTX@1|root,33IDK@2|Bacteria,1NJ7Q@1224|Proteobacteria,42XE5@68525|delta/epsilon subdivisions,2WTE3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SirB
WZS1_k127_2999303_2	234267.Acid_5073	1.87e-18	87.0	COG1918@1|root,COG1918@2|Bacteria,3Y92B@57723|Acidobacteria	57723|Acidobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
WZS1_k127_2999303_0	1267535.KB906767_gene1113	2.165e-242	766.0	COG0370@1|root,COG0370@2|Bacteria,3Y3CZ@57723|Acidobacteria,2JJQ0@204432|Acidobacteriia	204432|Acidobacteriia	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WZS1_k127_2999303_1	1379270.AUXF01000001_gene2452	2.619e-61	219.0	COG1600@1|root,COG1600@2|Bacteria,1ZU4X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
WZS1_k127_3008218_3	861299.J421_2765	3.975e-23	111.0	COG0244@1|root,COG0244@2|Bacteria,1ZTQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WZS1_k127_3008218_0	861299.J421_2764	8.52e-99	336.0	COG0081@1|root,COG0081@2|Bacteria,1ZSS7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WZS1_k127_3008218_2	469371.Tbis_0538	1.322e-57	203.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,4E2SZ@85010|Pseudonocardiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
WZS1_k127_3008218_1	861299.J421_2762	3.985e-75	260.0	COG0250@1|root,COG0250@2|Bacteria,1ZSS2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
WZS1_k127_3008218_6	255470.cbdbA959	4.496e-06	55.0	COG0690@1|root,COG0690@2|Bacteria,2G9VX@200795|Chloroflexi,34DH3@301297|Dehalococcoidia	301297|Dehalococcoidia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
WZS1_k127_3008218_4	861299.J421_2760	8.082e-22	98.0	COG0267@1|root,COG0267@2|Bacteria,1ZV8A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L33	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
WZS1_k127_3008218_5	644966.Tmar_2311	6.028e-21	92.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WCCR@538999|Clostridiales incertae sedis	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
WZS1_k127_3020387_6	379066.GAU_1177	6.827e-21	95.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WZS1_k127_3020387_1	861299.J421_2931	8.703e-72	259.0	28I3N@1|root,2Z87C@2|Bacteria,1ZT9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
WZS1_k127_3020387_8	1082933.MEA186_30762	0.00021	52.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43NVJ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WZS1_k127_3020387_3	506534.Rhein_2338	5.826e-51	198.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria,1X158@135613|Chromatiales	135613|Chromatiales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WZS1_k127_3020387_2	379066.GAU_1183	2.326e-59	214.0	COG0664@1|root,COG0664@2|Bacteria,1ZTHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WZS1_k127_3020387_5	215803.DB30_7550	2.352e-24	104.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,2YVT9@29|Myxococcales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WZS1_k127_3020387_0	379066.GAU_1184	2.446e-128	419.0	COG0216@1|root,COG0216@2|Bacteria,1ZSNT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WZS1_k127_3020387_4	1125863.JAFN01000001_gene1724	2.86e-46	183.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
WZS1_k127_3020387_7	1379270.AUXF01000005_gene498	1.952e-11	76.0	COG3679@1|root,COG3679@2|Bacteria,1ZTRW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
WZS1_k127_3058415_1	1379270.AUXF01000002_gene1196	7.812e-39	149.0	COG0515@1|root,COG0515@2|Bacteria,1ZT9E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_3058415_2	1519464.HY22_11300	7.666e-20	103.0	COG4219@1|root,COG4219@2|Bacteria,1FF12@1090|Chlorobi	1090|Chlorobi	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3058415_0	1379270.AUXF01000002_gene1198	4.776e-131	432.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1ZTCF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WZS1_k127_30657_6	1382304.JNIL01000001_gene1217	1.358e-39	155.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,4HC7I@91061|Bacilli	91061|Bacilli	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
WZS1_k127_30657_3	861299.J421_3232	3.616e-106	371.0	COG0498@1|root,COG0498@2|Bacteria,1ZT17@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS1_k127_30657_1	1379270.AUXF01000006_gene290	2.834e-202	657.0	COG0322@1|root,COG0322@2|Bacteria,1ZSXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
WZS1_k127_30657_2	1267535.KB906767_gene597	3.268e-135	452.0	COG0728@1|root,COG0728@2|Bacteria,3Y6N1@57723|Acidobacteria	57723|Acidobacteria	S	MviN-like protein	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
WZS1_k127_30657_4	861299.J421_3229	8.026e-61	230.0	COG4365@1|root,COG4365@2|Bacteria,1ZTG0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacillithiol biosynthesis BshC	-	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
WZS1_k127_30657_7	1385517.N800_10530	1.309e-32	133.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1X5XV@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WZS1_k127_30657_0	861299.J421_3227	1.538e-207	652.0	COG0334@1|root,COG0334@2|Bacteria,1ZSQB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS1_k127_30657_5	861299.J421_3226	1.029e-56	212.0	COG1663@1|root,COG1663@2|Bacteria,1ZTIE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
WZS1_k127_30657_8	243159.AFE_0487	0.0005045	47.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,1SACF@1236|Gammaproteobacteria,2NBVJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
WZS1_k127_3073696_1	861299.J421_4127	5.234e-235	739.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	-	-	3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	-	R02108,R02111,R02112,R11262	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM26,CBM_20,CBM_25,CBM_48,PUD
WZS1_k127_3073696_2	861299.J421_4129	5.058e-191	619.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
WZS1_k127_3073696_0	861299.J421_4130	2.81e-269	852.0	COG1629@1|root,COG4771@2|Bacteria,1ZVAQ@142182|Gemmatimonadetes	2|Bacteria	P	TonB dependent receptor	susC	-	-	ko:K21573	-	-	-	-	ko00000,ko02000	1.B.14.6.1	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WZS1_k127_3105697_3	525904.Tter_0854	1.568e-59	214.0	COG1926@1|root,COG1926@2|Bacteria,2NQVQ@2323|unclassified Bacteria	2|Bacteria	S	Phosphoribosyl transferase domain	prsT	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
WZS1_k127_3105697_2	1297742.A176_05554	3.151e-78	276.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,439QP@68525|delta/epsilon subdivisions,2X537@28221|Deltaproteobacteria,2Z01T@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix domain	dpbF	-	-	-	-	-	-	-	-	-	-	-	HHH_5,HHH_8
WZS1_k127_3105697_0	452637.Oter_3293	5.556e-212	672.0	COG0281@1|root,COG0281@2|Bacteria,46UI4@74201|Verrucomicrobia,3K7KY@414999|Opitutae	414999|Opitutae	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
WZS1_k127_3105697_1	867903.ThesuDRAFT_00352	7.736e-136	448.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3WD0A@538999|Clostridiales incertae sedis	186801|Clostridia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
WZS1_k127_313277_1	861299.J421_3824	3.755e-65	228.0	COG0336@1|root,COG0336@2|Bacteria,1ZT8K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WZS1_k127_313277_5	219305.MCAG_04273	7.851e-19	94.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,4DD1W@85008|Micromonosporales	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WZS1_k127_313277_3	1384066.JAGT01000001_gene1901	2.728e-22	98.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3WJSQ@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WZS1_k127_313277_0	861299.J421_3827	9.67e-176	561.0	COG0541@1|root,COG0541@2|Bacteria,1ZSPG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WZS1_k127_313277_2	1136417.AZWE01000004_gene4506	9.275e-33	136.0	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4DM1G@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS1_k127_313277_4	861299.J421_3830	7.678e-22	101.0	COG2856@1|root,COG2856@2|Bacteria,1ZSXU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3163138_5	395965.Msil_0666	2.13e-20	94.0	COG0802@1|root,COG3178@1|root,COG0802@2|Bacteria,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,3N9UA@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	MA20_24090	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,TsaE
WZS1_k127_3163138_0	379066.GAU_1953	3.283e-315	977.0	COG0556@1|root,COG0556@2|Bacteria,1ZSQS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WZS1_k127_3163138_4	326427.Cagg_0242	1.697e-42	174.0	COG2947@1|root,COG2947@2|Bacteria,2G93S@200795|Chloroflexi,375T3@32061|Chloroflexia	32061|Chloroflexia	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
WZS1_k127_3163138_2	379066.GAU_1955	4.028e-282	885.0	COG0317@1|root,COG0317@2|Bacteria,1ZT5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WZS1_k127_3163138_3	861299.J421_3564	5.657e-69	246.0	COG2003@1|root,COG2003@2|Bacteria,1ZTFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WZS1_k127_3163138_1	861299.J421_3566	6.349e-283	889.0	COG0653@1|root,COG0653@2|Bacteria,1ZSMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WZS1_k127_3181992_0	1192034.CAP_3083	8.204e-158	509.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria,2YTX0@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS1_k127_3181992_1	379066.GAU_3307	5.558e-118	386.0	COG2936@1|root,COG2936@2|Bacteria,1ZTD6@142182|Gemmatimonadetes	2|Bacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	cocE	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_3243952_7	204669.Acid345_2823	3.749e-17	82.0	COG2234@1|root,COG2234@2|Bacteria,3Y33F@57723|Acidobacteria,2JI7G@204432|Acidobacteriia	2|Bacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
WZS1_k127_3243952_6	1121861.KB899938_gene3988	9.136e-22	102.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	ygiN	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009268,GO:0009628,GO:0010447,GO:0016491,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114	-	-	-	-	-	-	-	-	-	iEcSMS35_1347.EcSMS35_3317	ABM
WZS1_k127_3243952_3	1049564.TevJSym_ar00510	2.127e-62	220.0	COG4106@1|root,COG4106@2|Bacteria,1QWJU@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS1_k127_3243952_4	1121904.ARBP01000026_gene629	3.82e-43	163.0	COG3832@1|root,COG3832@2|Bacteria,4NRDQ@976|Bacteroidetes,47VV2@768503|Cytophagia	976|Bacteroidetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WZS1_k127_3243952_1	1123278.KB893623_gene3429	1.082e-197	630.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_3243952_0	234267.Acid_4922	9.548e-294	917.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria	57723|Acidobacteria	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WZS1_k127_3243952_2	1163409.UUA_18219	2.151e-79	277.0	COG0657@1|root,COG0657@2|Bacteria,1RGPG@1224|Proteobacteria,1T3Q2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WZS1_k127_3243952_5	1121035.AUCH01000001_gene2052	1.624e-29	126.0	COG3016@1|root,COG3016@2|Bacteria,1NXYQ@1224|Proteobacteria,2VTNU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
WZS1_k127_3265360_8	861299.J421_3599	6.051e-15	78.0	2FD8C@1|root,345AC@2|Bacteria,1ZTXK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3265360_0	861299.J421_3601	2.422e-217	681.0	COG1260@1|root,COG1260@2|Bacteria,1ZT2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Myo-inositol-1-phosphate synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
WZS1_k127_3265360_6	379066.GAU_1998	2.653e-35	143.0	COG0558@1|root,COG0558@2|Bacteria,1ZTIP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WZS1_k127_3265360_3	1382356.JQMP01000003_gene1834	5.797e-89	314.0	COG3876@1|root,COG3876@2|Bacteria,2G655@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
WZS1_k127_3265360_2	518766.Rmar_0925	1.287e-111	396.0	COG1472@1|root,COG1680@1|root,COG1472@2|Bacteria,COG1680@2|Bacteria,4NET8@976|Bacteroidetes,1FJ9E@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Beta-lactamase,Glyco_hydro_3,Glyco_hydro_3_C
WZS1_k127_3265360_4	1379270.AUXF01000003_gene3856	1.692e-84	305.0	COG1680@1|root,COG1680@2|Bacteria,1ZT58@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_3265360_5	1379270.AUXF01000003_gene3855	1.883e-41	165.0	COG0316@1|root,COG0316@2|Bacteria,1ZTT0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
WZS1_k127_3265360_1	1379270.AUXF01000003_gene3853	3.489e-135	449.0	COG0591@1|root,COG0591@2|Bacteria,1ZTEB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WZS1_k127_3265360_7	1292373.H640_00807	1.241e-18	98.0	COG2971@1|root,COG2971@2|Bacteria,2GKBF@201174|Actinobacteria,4DSI3@85009|Propionibacteriales	201174|Actinobacteria	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WZS1_k127_3272545_8	266117.Rxyl_0995	6.116e-49	183.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,4CPW1@84995|Rubrobacteria	84995|Rubrobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WZS1_k127_3272545_10	1122613.ATUP01000001_gene482	5.764e-18	85.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,43YKY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
WZS1_k127_3272545_9	861299.J421_3376	3.917e-43	171.0	COG1183@1|root,COG1183@2|Bacteria,1ZTJP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
WZS1_k127_3272545_6	861299.J421_3375	2.337e-67	239.0	COG0688@1|root,COG0688@2|Bacteria,1ZU9Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
WZS1_k127_3272545_3	258594.RPA0558	5.285e-111	385.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TS0T@28211|Alphaproteobacteria,3JRJ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC2	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WZS1_k127_3272545_0	379066.GAU_1731	1.999e-167	542.0	COG0015@1|root,COG0015@2|Bacteria,1ZSVW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WZS1_k127_3272545_2	379066.GAU_1730	7.947e-121	413.0	COG0265@1|root,COG0265@2|Bacteria,1ZTAM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WZS1_k127_3272545_7	1379270.AUXF01000006_gene161	1.415e-65	232.0	COG0101@1|root,COG0101@2|Bacteria,1ZSRZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WZS1_k127_3272545_4	379066.GAU_1726	2.986e-79	270.0	COG1974@1|root,COG1974@2|Bacteria,1ZSSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WZS1_k127_3272545_5	1379270.AUXF01000006_gene168	2.875e-74	271.0	COG1413@1|root,COG1413@2|Bacteria,1ZUI4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WZS1_k127_3272545_1	379066.GAU_1721	1.19e-135	447.0	COG2206@1|root,COG2206@2|Bacteria,1ZUTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS1_k127_3272545_11	1173029.JH980292_gene3612	7.59e-13	82.0	COG0840@1|root,COG5002@1|root,COG0840@2|Bacteria,COG5002@2|Bacteria,1GBFY@1117|Cyanobacteria,1HE1Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Methyl-accepting chemotaxis sensory transducer with Pas Pac sensor	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PAS_3,PAS_4,PAS_8,PAS_9
WZS1_k127_3301878_5	314225.ELI_02315	1.1e-09	59.0	COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2TT6C@28211|Alphaproteobacteria,2K35D@204457|Sphingomonadales	204457|Sphingomonadales	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WZS1_k127_3301878_1	441620.Mpop_4542	3.879e-78	263.0	COG2514@1|root,COG2514@2|Bacteria,1RBC7@1224|Proteobacteria,2U5JP@28211|Alphaproteobacteria,1JUR8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	MA20_22790	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
WZS1_k127_3301878_4	861299.J421_2048	1.941e-11	66.0	COG0828@1|root,COG0828@2|Bacteria,1ZU81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S21	-	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WZS1_k127_3301878_3	379066.GAU_2739	1.004e-30	122.0	COG1278@1|root,COG1278@2|Bacteria,1ZV0Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Ribonuclease B OB domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WZS1_k127_3301878_0	861299.J421_5706	1.207e-211	678.0	COG0488@1|root,COG0488@2|Bacteria,1ZT87@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
WZS1_k127_3301878_2	379066.GAU_2378	2.035e-49	185.0	COG2362@1|root,COG2362@2|Bacteria,1ZUMF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
WZS1_k127_3303855_4	380358.XALC_2047	2.751e-29	118.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,1RP0R@1236|Gammaproteobacteria,1X55T@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	ampC2	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WZS1_k127_3303855_2	861299.J421_5741	5.726e-78	278.0	COG0596@1|root,COG1228@1|root,COG0596@2|Bacteria,COG1228@2|Bacteria,1ZV1H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_3303855_0	1304874.JAFY01000007_gene2487	5.18e-167	538.0	COG0626@1|root,COG0626@2|Bacteria,3TC2M@508458|Synergistetes	508458|Synergistetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WZS1_k127_3303855_3	582899.Hden_0329	3.703e-72	256.0	COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2TRYE@28211|Alphaproteobacteria,3N8BX@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.24	ko:K01055,ko:K19707	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Abhydrolase_1
WZS1_k127_3303855_1	1379270.AUXF01000005_gene404	3.001e-87	308.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS1_k127_3303855_5	502025.Hoch_6177	7.326e-23	100.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,42SKW@68525|delta/epsilon subdivisions,2X87K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
WZS1_k127_3311212_3	694429.Pyrfu_0852	0.000123	48.0	COG2362@1|root,arCOG04080@2157|Archaea,2XQ2P@28889|Crenarchaeota	28889|Crenarchaeota	E	PFAM peptidase M55 D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
WZS1_k127_3311212_1	331678.Cphamn1_1217	1.347e-83	307.0	COG0729@1|root,COG0729@2|Bacteria,1FFQQ@1090|Chlorobi	1090|Chlorobi	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
WZS1_k127_3311212_0	518766.Rmar_0345	9.714e-169	542.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes	976|Bacteroidetes	S	TIGRFAM amidohydrolase	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_3311212_2	761193.Runsl_0279	8.041e-24	102.0	COG1473@1|root,COG1473@2|Bacteria,4NEKH@976|Bacteroidetes,47N92@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_333532_2	215803.DB30_0609	1.796e-24	104.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2YW0B@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WZS1_k127_333532_0	861299.J421_1702	1.106e-219	695.0	COG3653@1|root,COG3653@2|Bacteria,1ZTDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_333532_1	1094980.Mpsy_3062	6.79e-92	307.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,2NAUF@224756|Methanomicrobia	224756|Methanomicrobia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WZS1_k127_3357149_0	204669.Acid345_2823	3.174e-211	676.0	COG2234@1|root,COG2234@2|Bacteria,3Y33F@57723|Acidobacteria,2JI7G@204432|Acidobacteriia	2|Bacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
WZS1_k127_3357149_1	861299.J421_1321	1.004e-159	507.0	COG0115@1|root,COG0115@2|Bacteria,1ZTH5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WZS1_k127_3357149_3	861299.J421_2451	7.09e-56	217.0	COG1574@1|root,COG1574@2|Bacteria,1ZTC9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS1_k127_3357149_2	1379270.AUXF01000002_gene1544	1.171e-70	253.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_3364700_1	886293.Sinac_5836	1.977e-159	522.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_3364700_3	1379270.AUXF01000007_gene887	1.182e-118	395.0	COG0451@1|root,COG0451@2|Bacteria,1ZUNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	1.3.1.45	ko:K05281	ko00943,ko01110,map00943,map01110	-	R06562,R06563,R07747,R07751	RC00805	ko00000,ko00001,ko01000	-	-	-	-
WZS1_k127_3364700_2	1123060.JONP01000004_gene704	1.825e-132	441.0	COG3202@1|root,COG3202@2|Bacteria,1MVP5@1224|Proteobacteria,2U1N0@28211|Alphaproteobacteria,2JW2Q@204441|Rhodospirillales	204441|Rhodospirillales	C	ATP ADP translocase	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS1_k127_3364700_4	984262.SGRA_1739	3.419e-57	229.0	COG1808@1|root,COG1808@2|Bacteria,4NDXI@976|Bacteroidetes,1IPNW@117747|Sphingobacteriia	976|Bacteroidetes	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
WZS1_k127_3364700_0	392499.Swit_2227	4.213e-194	650.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1R7EM@1224|Proteobacteria,2TRZT@28211|Alphaproteobacteria,2K8UV@204457|Sphingomonadales	204457|Sphingomonadales	C	PQQ-like domain	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
WZS1_k127_3364700_5	1499967.BAYZ01000095_gene4289	9.906e-45	168.0	COG3760@1|root,COG3760@2|Bacteria	2|Bacteria	S	aminoacyl-tRNA metabolism involved in translational fidelity	proX	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WZS1_k127_3364700_6	379066.GAU_1665	8.385e-06	50.0	COG1416@1|root,COG1416@2|Bacteria,1ZU3V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3368721_1	452637.Oter_1367	2.006e-78	265.0	COG0262@1|root,COG0262@2|Bacteria,46XD6@74201|Verrucomicrobia,3K9XY@414999|Opitutae	414999|Opitutae	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
WZS1_k127_3368721_4	401053.AciPR4_2460	1.638e-09	65.0	COG4319@1|root,COG4319@2|Bacteria,3Y5FP@57723|Acidobacteria,2JN7M@204432|Acidobacteriia	204432|Acidobacteriia	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
WZS1_k127_3368721_3	204669.Acid345_4011	3.545e-21	98.0	2ED19@1|root,336Y7@2|Bacteria,3Y95N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3368721_0	1379270.AUXF01000007_gene994	1.57e-192	633.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000007_gene994|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3368721_2	1379270.AUXF01000007_gene994	2.626e-22	98.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000007_gene994|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3376378_2	1379270.AUXF01000002_gene1544	4.997e-40	158.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_3376378_4	861299.J421_1249	1.841e-22	109.0	2AG3M@1|root,31687@2|Bacteria,1ZV0Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3376378_0	1379270.AUXF01000001_gene2303	1.326e-185	606.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1ZUB1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
WZS1_k127_3376378_3	1379270.AUXF01000001_gene2302	2.022e-39	158.0	COG4249@1|root,COG4249@2|Bacteria,1ZUQX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3376378_1	1379270.AUXF01000001_gene2301	1.943e-61	228.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1ZUF5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3386802_5	1267533.KB906736_gene884	2.595e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,3Y7WN@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
WZS1_k127_3386802_2	861299.J421_1652	3.985e-50	198.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	yhhT	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS1_k127_3386802_1	1379270.AUXF01000001_gene2611	2.182e-66	236.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
WZS1_k127_3386802_6	1205680.CAKO01000038_gene1594	0.0003029	50.0	2DRFV@1|root,33BJD@2|Bacteria,1NM2T@1224|Proteobacteria,2UX6G@28211|Alphaproteobacteria,2JYBR@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3386802_0	861299.J421_3834	6.788e-87	300.0	COG4783@1|root,COG4783@2|Bacteria,1ZSU4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WZS1_k127_3386802_3	379066.GAU_0932	7.247e-19	95.0	2EVUZ@1|root,33P8Q@2|Bacteria,1ZTJQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3386802_4	96561.Dole_2317	1.395e-15	78.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3402674_8	1267533.KB906738_gene2316	1.303e-27	115.0	2AI77@1|root,318MJ@2|Bacteria,3Y7RV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3402674_1	1379270.AUXF01000001_gene1925	6.298e-146	473.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56,SHD1
WZS1_k127_3402674_5	1242864.D187_006013	2.487e-74	263.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WZS1_k127_3402674_10	1173029.JH980292_gene606	2.459e-10	72.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1G0VA@1117|Cyanobacteria,1H9ND@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	cya1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
WZS1_k127_3402674_3	1168034.FH5T_19015	1.503e-118	398.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3402674_9	237368.SCABRO_04028	3.812e-25	121.0	COG0644@1|root,COG0664@1|root,COG0644@2|Bacteria,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	prnA	-	1.14.19.9	ko:K07058,ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_5,Trp_halogenase,cNMP_binding
WZS1_k127_3402674_2	331678.Cphamn1_1855	1.088e-134	448.0	COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2
WZS1_k127_3402674_0	595460.RRSWK_07136	1.673e-173	557.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
WZS1_k127_3402674_7	1177928.TH2_01990	1.803e-50	188.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2U70V@28211|Alphaproteobacteria,2JT1J@204441|Rhodospirillales	204441|Rhodospirillales	S	Appr-1'-p processing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Macro
WZS1_k127_3402674_6	656024.FsymDg_1590	4.437e-57	209.0	COG4221@1|root,COG4221@2|Bacteria,2IK15@201174|Actinobacteria	201174|Actinobacteria	S	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WZS1_k127_3402674_4	357808.RoseRS_0423	5.348e-77	263.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
WZS1_k127_3413152_4	1122137.AQXF01000005_gene1070	1.274e-21	94.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2TU6T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WZS1_k127_3413152_1	595537.Varpa_1843	7.917e-99	335.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,Fib_succ_major
WZS1_k127_3413152_0	1519464.HY22_04445	4.123e-215	694.0	COG1770@1|root,COG1770@2|Bacteria,1FDQZ@1090|Chlorobi	1090|Chlorobi	E	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	3.4.21.26,3.4.21.83	ko:K01322,ko:K01354	ko04614,ko05142,ko05143,map04614,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WZS1_k127_3413152_2	84531.JMTZ01000003_gene2339	1.206e-84	294.0	COG0730@1|root,COG0730@2|Bacteria,1R6MR@1224|Proteobacteria,1S0QW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
WZS1_k127_3413152_3	518766.Rmar_1472	1.799e-69	250.0	COG0491@1|root,COG0491@2|Bacteria,4NHXR@976|Bacteroidetes,1FJDJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WZS1_k127_3427001_2	760192.Halhy_4898	2.757e-31	136.0	COG3250@1|root,COG3867@1|root,COG3250@2|Bacteria,COG3867@2|Bacteria,4NEWN@976|Bacteroidetes,1IRAX@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WZS1_k127_3427001_0	215803.DB30_0609	1.095e-91	312.0	COG1402@1|root,COG1402@2|Bacteria,1MXR9@1224|Proteobacteria,42QNA@68525|delta/epsilon subdivisions,2WIN0@28221|Deltaproteobacteria,2YW0B@29|Myxococcales	28221|Deltaproteobacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WZS1_k127_3427001_1	861299.J421_1702	2.938e-47	175.0	COG3653@1|root,COG3653@2|Bacteria,1ZTDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_3449454_9	379066.GAU_1780	5.529e-33	132.0	COG4770@1|root,COG4770@2|Bacteria,1ZTVQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
WZS1_k127_3449454_5	1379270.AUXF01000006_gene117	3.124e-59	210.0	COG0102@1|root,COG0102@2|Bacteria,1ZTIS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WZS1_k127_3449454_7	1379270.AUXF01000006_gene118	2.689e-49	182.0	COG0103@1|root,COG0103@2|Bacteria,1ZTM0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WZS1_k127_3449454_0	1379270.AUXF01000006_gene119	2.907e-100	341.0	COG0052@1|root,COG0052@2|Bacteria,1ZSNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WZS1_k127_3449454_3	379066.GAU_1775	8.879e-71	249.0	COG0264@1|root,COG0264@2|Bacteria,1ZT2Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WZS1_k127_3449454_2	1379270.AUXF01000006_gene121	2.931e-88	301.0	COG0528@1|root,COG0528@2|Bacteria,1ZSY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS1_k127_3449454_4	379066.GAU_1773	6.199e-60	223.0	COG0233@1|root,COG0233@2|Bacteria,1ZTI2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WZS1_k127_3449454_1	861299.J421_3408	2.02e-92	319.0	COG0020@1|root,COG0020@2|Bacteria,1ZSNJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WZS1_k127_3449454_8	861299.J421_3407	4.727e-49	186.0	COG4589@1|root,COG4589@2|Bacteria,1ZTGH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WZS1_k127_3449454_6	861299.J421_3406	4.19e-56	203.0	COG0743@1|root,COG0743@2|Bacteria,1ZTFR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
WZS1_k127_3493234_8	861299.J421_0829	3.476e-13	71.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GAF,HTH_8,Sigma54_activat
WZS1_k127_3493234_10	448385.sce5225	1.357e-08	66.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,4389V@68525|delta/epsilon subdivisions,2X3J8@28221|Deltaproteobacteria,2YWAY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WZS1_k127_3493234_3	880073.Calab_0511	7.073e-57	206.0	COG4221@1|root,COG4221@2|Bacteria,2NPJV@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short
WZS1_k127_3493234_11	1089550.ATTH01000001_gene2535	7.102e-08	63.0	2AAY5@1|root,310BG@2|Bacteria,4PESW@976|Bacteroidetes,1FJJG@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	BFD-like [2Fe-2S] binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_BFD
WZS1_k127_3493234_1	926569.ANT_11780	1.415e-57	221.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WZS1_k127_3493234_4	237368.SCABRO_03159	4.428e-44	184.0	COG3170@1|root,COG3170@2|Bacteria,2J3MN@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3493234_0	234267.Acid_0826	8.469e-78	273.0	COG0803@1|root,COG0803@2|Bacteria,3Y97A@57723|Acidobacteria	57723|Acidobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
WZS1_k127_3493234_2	237368.SCABRO_03161	2.478e-57	220.0	COG1121@1|root,COG1121@2|Bacteria,2IYC3@203682|Planctomycetes	203682|Planctomycetes	P	COG1121 ABC-type Mn Zn transport systems ATPase component	-	-	-	ko:K11607,ko:K11710	ko02010,map02010	M00317,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.7,3.A.1.15.9	-	-	ABC_tran
WZS1_k127_3493234_6	290397.Adeh_2337	6.354e-31	133.0	COG1108@1|root,COG1108@2|Bacteria,1Q1G9@1224|Proteobacteria,4378R@68525|delta/epsilon subdivisions,2X2BN@28221|Deltaproteobacteria,2YX1Q@29|Myxococcales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
WZS1_k127_3493234_9	1267535.KB906767_gene1078	1.047e-08	64.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
WZS1_k127_3493234_5	379066.GAU_2903	2.709e-43	167.0	COG2217@1|root,COG2217@2|Bacteria,1ZTC7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS1_k127_3569353_0	1185876.BN8_03382	0.0	1207.0	COG4447@1|root,COG4447@2|Bacteria,4NJFX@976|Bacteroidetes,47M9G@768503|Cytophagia	976|Bacteroidetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WZS1_k127_3569353_3	765911.Thivi_1699	9.827e-64	228.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,1S5UD@1236|Gammaproteobacteria,1WZ6R@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3569353_2	796606.BMMGA3_09045	8.435e-117	389.0	COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,4HDUI@91061|Bacilli,1ZBD0@1386|Bacillus	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WZS1_k127_3569353_4	240015.ACP_0708	1.412e-31	143.0	2B4YW@1|root,31XRX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3569353_1	945713.IALB_1786	6.826e-168	557.0	COG4774@1|root,COG4774@2|Bacteria	2|Bacteria	P	siderophore transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	AMIN,Plug,STN,TonB_dep_Rec
WZS1_k127_357201_5	1144275.COCOR_06958	4.198e-13	72.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
WZS1_k127_357201_2	1125863.JAFN01000001_gene1846	9.118e-61	216.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS1_k127_357201_0	1027292.HMPREF9372_3583	7.082e-89	313.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli,26CZ6@186818|Planococcaceae	91061|Bacilli	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WZS1_k127_357201_3	379066.GAU_1990	4.467e-59	217.0	COG0613@1|root,COG0613@2|Bacteria,1ZTHM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
WZS1_k127_357201_4	1379270.AUXF01000003_gene3865	1.898e-14	78.0	2FHQX@1|root,349IG@2|Bacteria,1ZU2X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_357201_1	861299.J421_3595	3.857e-87	296.0	COG0508@1|root,COG0508@2|Bacteria,1ZT7I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WZS1_k127_3587276_2	506534.Rhein_3151	1.149e-41	175.0	COG0729@1|root,COG0729@2|Bacteria,1QVUN@1224|Proteobacteria,1T2JF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein protective antigen OMA87	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
WZS1_k127_3587276_5	861299.J421_0446	6.916e-16	89.0	2F3M0@1|root,33WE8@2|Bacteria,1ZTTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3587276_0	861299.J421_0447	3.222e-116	386.0	COG2107@1|root,COG2107@2|Bacteria,1ZTVU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
WZS1_k127_3587276_1	861299.J421_0450	3.982e-99	334.0	COG3437@1|root,COG3437@2|Bacteria,1ZTD3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
WZS1_k127_3587276_4	391600.ABRU01000050_gene265	3.006e-16	91.0	COG0745@1|root,COG3920@1|root,COG0745@2|Bacteria,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,2TSSQ@28211|Alphaproteobacteria,2KHJS@204458|Caulobacterales	204458|Caulobacterales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,HisKA_2,Response_reg
WZS1_k127_3587276_3	1379270.AUXF01000002_gene1468	3.63e-31	129.0	COG0789@1|root,COG0789@2|Bacteria,1ZTHT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
WZS1_k127_358985_1	861299.J421_1035	1.733e-31	133.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
WZS1_k127_358985_2	234267.Acid_3232	2.348e-20	95.0	29WUM@1|root,30IG2@2|Bacteria,3Y90X@57723|Acidobacteria	57723|Acidobacteria	S	Putative mono-oxygenase ydhR	-	-	-	-	-	-	-	-	-	-	-	-	ydhR
WZS1_k127_358985_0	506534.Rhein_2117	2.921e-35	138.0	COG4898@1|root,COG4898@2|Bacteria,1N0Z1@1224|Proteobacteria,1SQ7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3609234_0	1379270.AUXF01000001_gene2734	1.349e-222	714.0	COG0841@1|root,COG0841@2|Bacteria,1ZUDY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WZS1_k127_3613682_2	644282.Deba_1076	3.104e-56	203.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WZS1_k127_3613682_3	246194.CHY_0010	2.568e-05	49.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,42FPF@68295|Thermoanaerobacterales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WZS1_k127_3613682_0	861299.J421_1168	1.07e-94	323.0	COG1744@1|root,COG1744@2|Bacteria,1ZSMV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WZS1_k127_3613682_1	497964.CfE428DRAFT_0749	4.38e-76	263.0	COG0327@1|root,COG0327@2|Bacteria	2|Bacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	ybgI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
WZS1_k127_3619929_3	391600.ABRU01000039_gene1996	1.749e-07	55.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,2KEXK@204458|Caulobacterales	204458|Caulobacterales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WZS1_k127_3619929_0	926566.Terro_4115	7.347e-125	413.0	COG0438@1|root,COG0438@2|Bacteria,3Y3CI@57723|Acidobacteria,2JKK7@204432|Acidobacteriia	204432|Acidobacteriia	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WZS1_k127_3619929_1	926550.CLDAP_24620	4.664e-47	179.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi	200795|Chloroflexi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WZS1_k127_3619929_2	1268072.PSAB_15720	1.182e-14	85.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli,26QTA@186822|Paenibacillaceae	91061|Bacilli	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
WZS1_k127_3643074_1	861299.J421_3441	9.325e-189	603.0	COG1418@1|root,COG1418@2|Bacteria,1ZT0I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WZS1_k127_3643074_3	861299.J421_3440	1.71e-107	355.0	COG0190@1|root,COG0190@2|Bacteria,1ZSVX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WZS1_k127_3643074_4	1379270.AUXF01000006_gene91	4.482e-81	295.0	COG1570@1|root,COG1570@2|Bacteria,1ZT8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WZS1_k127_3643074_7	1122139.KB907864_gene2022	5.031e-09	60.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1XM23@135619|Oceanospirillales	135619|Oceanospirillales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WZS1_k127_3643074_6	861299.J421_3437	1.292e-68	244.0	COG0142@1|root,COG0142@2|Bacteria,1ZSR3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WZS1_k127_3643074_0	861299.J421_3436	7.895e-239	754.0	COG1154@1|root,COG1154@2|Bacteria,1ZSP2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
WZS1_k127_3643074_5	379066.GAU_1865	1.033e-75	264.0	COG0061@1|root,COG0061@2|Bacteria,1ZT32@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WZS1_k127_3643074_2	861299.J421_3434	2.409e-151	508.0	COG0497@1|root,COG0497@2|Bacteria,1ZSV4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	May be involved in recombinational repair of damaged DNA	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
WZS1_k127_3684730_0	861299.J421_1048	8.68e-238	762.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WZS1_k127_3684730_1	861299.J421_3996	8.991e-72	259.0	COG2954@1|root,COG5607@1|root,COG2954@2|Bacteria,COG5607@2|Bacteria,1ZTYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
WZS1_k127_3740400_1	709991.Odosp_3395	2.177e-84	282.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,4NFUN@976|Bacteroidetes,2FNNY@200643|Bacteroidia,22VV0@171551|Porphyromonadaceae	976|Bacteroidetes	S	membrane	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
WZS1_k127_3740400_4	998674.ATTE01000001_gene3159	4.928e-67	236.0	COG2866@1|root,COG2866@2|Bacteria,1N9AY@1224|Proteobacteria,1RRGU@1236|Gammaproteobacteria,4625I@72273|Thiotrichales	72273|Thiotrichales	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WZS1_k127_3740400_3	1168065.DOK_14669	9.648e-74	255.0	COG1876@1|root,COG1876@2|Bacteria,1N2IC@1224|Proteobacteria,1S0DU@1236|Gammaproteobacteria,1J68J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1876 D-alanyl-D-alanine carboxypeptidase	vanY	-	-	-	-	-	-	-	-	-	-	-	VanY
WZS1_k127_3740400_5	379066.GAU_3662	1.114e-49	181.0	28RT4@1|root,2ZE5G@2|Bacteria,1ZV80@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3740400_6	1123277.KB893174_gene6002	4.379e-39	156.0	COG0346@1|root,COG0346@2|Bacteria,4NRR7@976|Bacteroidetes,47QT0@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WZS1_k127_3740400_0	580332.Slit_1219	2.906e-141	462.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VNB4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA1	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
WZS1_k127_3740400_2	1047013.AQSP01000120_gene970	2.667e-78	273.0	COG2367@1|root,COG2367@2|Bacteria,2NQ4B@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
WZS1_k127_3758964_3	1379270.AUXF01000002_gene1586	5.768e-15	89.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1586|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3758964_1	1173026.Glo7428_4957	8.594e-119	400.0	COG0154@1|root,COG0154@2|Bacteria,1G1H1@1117|Cyanobacteria	1117|Cyanobacteria	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit	-	-	-	ko:K21801	ko00380,ko01100,map00380,map01100	-	-	-	ko00000,ko00001,ko01000	-	-	-	Amidase
WZS1_k127_3758964_2	1379270.AUXF01000007_gene994	6.287e-58	210.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000007_gene994|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3758964_0	861299.J421_0584	8.458e-288	899.0	COG0308@1|root,COG0308@2|Bacteria,1ZT68@142182|Gemmatimonadetes	2|Bacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WZS1_k127_3768677_4	861299.J421_1802	5.162e-12	76.0	2F4S7@1|root,33XEY@2|Bacteria,1ZTM4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3768677_0	246197.MXAN_0863	6.509e-170	547.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,42NTK@68525|delta/epsilon subdivisions,2WIV0@28221|Deltaproteobacteria,2YU7E@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	ko:K08997	-	-	-	-	ko00000	-	-	-	UPF0061
WZS1_k127_3768677_1	251229.Chro_1581	3.565e-112	380.0	COG1914@1|root,COG1914@2|Bacteria,1GIFV@1117|Cyanobacteria,3VM6A@52604|Pleurocapsales	1117|Cyanobacteria	P	H( )-stimulated, divalent metal cation uptake system	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3768677_3	234267.Acid_2007	1.406e-63	229.0	COG0506@1|root,COG0506@2|Bacteria,3Y2G8@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
WZS1_k127_3768677_2	1415780.JPOG01000001_gene961	5.204e-84	304.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,1RPS8@1236|Gammaproteobacteria,1X78Y@135614|Xanthomonadales	135614|Xanthomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WZS1_k127_377083_4	1125863.JAFN01000001_gene1608	1.34e-26	121.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
WZS1_k127_377083_2	861299.J421_0145	1.027e-156	499.0	COG0451@1|root,COG0451@2|Bacteria,1ZUJJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WZS1_k127_377083_1	246197.MXAN_1048	2.971e-161	518.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WZS1_k127_377083_0	379066.GAU_0583	2.487e-180	573.0	COG0677@1|root,COG0677@2|Bacteria,1ZT42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WZS1_k127_377083_3	1121091.AUMP01000008_gene3581	2.108e-27	113.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HD4F@91061|Bacilli	91061|Bacilli	E	Belongs to the DegT DnrJ EryC1 family	degT	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WZS1_k127_3825876_3	379066.GAU_2299	1.067e-08	64.0	COG4805@1|root,COG4805@2|Bacteria,1ZUMK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WZS1_k127_3825876_0	1232410.KI421412_gene357	1.034e-99	335.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,43TDI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
WZS1_k127_3825876_1	861299.J421_4214	8.187e-42	169.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4347,Gram_pos_anchor,SdrD_B,VPEP
WZS1_k127_3825876_2	379066.GAU_0865	5.931e-34	142.0	COG4801@1|root,COG4801@2|Bacteria,1ZV03@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3840885_12	1280941.HY2_06980	7.903e-09	65.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,43X7P@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
WZS1_k127_3840885_3	379066.GAU_1979	5.259e-92	312.0	COG0167@1|root,COG0167@2|Bacteria,1ZT86@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WZS1_k127_3840885_8	713587.THITH_07985	9.829e-40	166.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1WW0C@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
WZS1_k127_3840885_11	379066.GAU_1977	2.625e-12	74.0	COG0257@1|root,COG0257@2|Bacteria,1ZVAA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WZS1_k127_3840885_6	861299.J421_3579	6.078e-56	198.0	COG0099@1|root,COG0099@2|Bacteria,1ZTNX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WZS1_k127_3840885_7	861299.J421_3578	6.929e-55	195.0	COG0100@1|root,COG0100@2|Bacteria,1ZTMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WZS1_k127_3840885_4	861299.J421_3577	1.209e-82	279.0	COG0522@1|root,COG0522@2|Bacteria,1ZTGJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WZS1_k127_3840885_2	861299.J421_3576	6.032e-141	455.0	COG0202@1|root,COG0202@2|Bacteria,1ZTEV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WZS1_k127_3840885_9	861299.J421_3575	8.195e-38	146.0	COG0203@1|root,COG0203@2|Bacteria,1ZTPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WZS1_k127_3840885_10	796940.HMPREF9628_00853	4.043e-21	94.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WZS1_k127_3840885_0	1379270.AUXF01000003_gene3886	8.819e-155	494.0	COG1089@1|root,COG1089@2|Bacteria,1ZSR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WZS1_k127_3840885_5	861299.J421_3572	1.705e-65	238.0	COG0451@1|root,COG0451@2|Bacteria,1ZT9D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WZS1_k127_3840885_1	379066.GAU_1968	1.039e-152	487.0	COG0458@1|root,COG0458@2|Bacteria,1ZSPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
WZS1_k127_3857398_0	1267534.KB906759_gene1822	5.383e-109	384.0	COG2409@1|root,COG2409@2|Bacteria	2|Bacteria	D	Drug exporters of the RND superfamily	mmpL3	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264	-	ko:K06994,ko:K07003,ko:K20466,ko:K20470	-	-	-	-	ko00000,ko02000	2.A.6.5.5,2.A.6.5.6	-	-	MMPL
WZS1_k127_3857398_4	4558.Sb09g025870.1	1.035e-06	61.0	KOG1565@1|root,KOG1565@2759|Eukaryota,37PZP@33090|Viridiplantae,3GFZZ@35493|Streptophyta,3KNKT@4447|Liliopsida,3IN5U@38820|Poales	35493|Streptophyta	O	Belongs to the peptidase M10A family	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M10
WZS1_k127_3857398_3	1150474.JQJI01000002_gene1102	1.042e-29	120.0	COG2151@1|root,COG2151@2|Bacteria,2GDA3@200918|Thermotogae	200918|Thermotogae	S	metal-sulfur cluster biosynthetic	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
WZS1_k127_3857398_1	861299.J421_2109	7.694e-108	362.0	COG0349@1|root,COG0349@2|Bacteria,1ZSPS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WZS1_k127_3857398_2	1128421.JAGA01000003_gene2894	7.797e-60	216.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	pcaD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
WZS1_k127_3872904_3	247490.KSU1_D0807	4.639e-43	169.0	2BRMQ@1|root,32KM4@2|Bacteria,2J4AR@203682|Planctomycetes	247490.KSU1_D0807|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3872904_2	1379270.AUXF01000002_gene1700	4.644e-59	212.0	28NN4@1|root,2ZBNJ@2|Bacteria,1ZTTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3872904_4	379066.GAU_2752	1.942e-18	95.0	2F4S7@1|root,33XEY@2|Bacteria,1ZTM4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3872904_0	861299.J421_2750	1.994e-142	473.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K22348	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,SdrD_B,TIG,fn3_3
WZS1_k127_3872904_1	460265.Mnod_1231	1.336e-87	299.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria,1JS2Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS1_k127_3872904_5	323097.Nham_0405	3.408e-09	64.0	COG1555@1|root,COG1555@2|Bacteria,1N7MI@1224|Proteobacteria,2UFBA@28211|Alphaproteobacteria,3K5TB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3
WZS1_k127_3886882_0	1379270.AUXF01000001_gene2024	0.0	1299.0	COG4447@1|root,COG4447@2|Bacteria,1ZT1T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WZS1_k127_3894255_5	379066.GAU_1210	8.35e-61	219.0	COG4409@1|root,COG4409@2|Bacteria,1ZUBR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3894255_0	1379270.AUXF01000002_gene1363	4.419e-189	621.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WZS1_k127_3894255_6	1117647.M5M_10750	4.006e-42	166.0	COG2819@1|root,COG2819@2|Bacteria,1RAB4@1224|Proteobacteria,1S2JK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	hydrolase of the alpha beta superfamily	Z012_06880	-	-	-	-	-	-	-	-	-	-	-	Esterase
WZS1_k127_3894255_3	861299.J421_0422	3.828e-137	447.0	COG0189@1|root,COG0189@2|Bacteria,1ZTDE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3894255_2	379066.GAU_1360	6.37e-159	515.0	COG2308@1|root,COG2308@2|Bacteria,1ZT4M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
WZS1_k127_3894255_1	861299.J421_0420	5.246e-164	545.0	COG2170@1|root,COG2170@2|Bacteria,1ZTBN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	-	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
WZS1_k127_3894255_8	215803.DB30_8595	2.25e-13	79.0	COG3591@1|root,COG3591@2|Bacteria,1Q1GX@1224|Proteobacteria,439CQ@68525|delta/epsilon subdivisions,2X4M4@28221|Deltaproteobacteria,2YZ8H@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3894255_9	187303.BN69_1730	5.728e-12	76.0	2ECN6@1|root,336K2@2|Bacteria,1NVTD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_3894255_4	379066.GAU_1361	3.832e-94	322.0	COG2071@1|root,COG2071@2|Bacteria,1ZSXR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
WZS1_k127_3894255_7	861299.J421_0945	8.972e-40	157.0	COG4772@1|root,COG4772@2|Bacteria,1ZSWK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
WZS1_k127_391340_0	861299.J421_3250	9.59e-181	592.0	COG1508@1|root,COG1508@2|Bacteria,1ZT13@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WZS1_k127_391340_1	861299.J421_3251	2.609e-115	391.0	COG1137@1|root,COG1137@2|Bacteria,1ZT4S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
WZS1_k127_391340_3	861299.J421_3253	2.577e-23	106.0	2DWX3@1|root,342B9@2|Bacteria,1ZTXN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	-	-	-	-	-	-	-	-	-	LptC
WZS1_k127_391340_2	379066.GAU_1621	1.187e-28	119.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1ZT08@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
WZS1_k127_3944044_7	713586.KB900536_gene552	0.0003462	48.0	COG1404@1|root,COG1653@1|root,COG1404@2|Bacteria,COG1653@2|Bacteria,1R5TB@1224|Proteobacteria,1RSBF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
WZS1_k127_3944044_2	1379270.AUXF01000003_gene3485	3.447e-81	277.0	COG0500@1|root,COG2226@2|Bacteria,1ZSNE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
WZS1_k127_3944044_1	1379270.AUXF01000003_gene3487	7.331e-90	304.0	COG0382@1|root,COG0382@2|Bacteria,1ZT35@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WZS1_k127_3944044_0	237368.SCABRO_01870	1.749e-170	563.0	COG0043@1|root,COG0043@2|Bacteria,2IYCA@203682|Planctomycetes	203682|Planctomycetes	H	COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
WZS1_k127_3944044_3	379066.GAU_2438	1.53e-78	269.0	COG0163@1|root,COG0163@2|Bacteria,1ZTIK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
WZS1_k127_3944044_4	1242864.D187_008328	7.793e-24	105.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,4338I@68525|delta/epsilon subdivisions,2WXBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WZS1_k127_3944044_6	717606.PaecuDRAFT_2026	6.212e-05	48.0	COG0596@1|root,COG0596@2|Bacteria,1V18A@1239|Firmicutes,4HEMC@91061|Bacilli,26X8D@186822|Paenibacillaceae	91061|Bacilli	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS1_k127_3944044_5	682795.AciX8_3374	1.312e-08	62.0	COG2318@1|root,COG2318@2|Bacteria,3Y569@57723|Acidobacteria,2JMW6@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_3953424_0	383372.Rcas_2461	2.637e-157	521.0	COG1960@1|root,COG1960@2|Bacteria,2G8AV@200795|Chloroflexi,376RG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.8	ko:K00255,ko:K11731	ko00071,ko00281,ko01100,ko01212,ko03320,map00071,map00281,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754,R08089	RC00052,RC01893	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS1_k127_3953424_1	251221.35211608	1.459e-154	496.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
WZS1_k127_3953424_2	1121124.JNIX01000014_gene1166	2.713e-51	200.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2TSXW@28211|Alphaproteobacteria,2KFBS@204458|Caulobacterales	204458|Caulobacterales	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS1_k127_3964743_0	1379270.AUXF01000006_gene185	2.207e-202	645.0	COG3185@1|root,COG3185@2|Bacteria,1ZT5D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
WZS1_k127_398588_2	338963.Pcar_1339	1.221e-60	223.0	28IWG@1|root,2Z8US@2|Bacteria,1NHDW@1224|Proteobacteria,42MHT@68525|delta/epsilon subdivisions,2WMMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
WZS1_k127_398588_0	861299.J421_6087	1.655e-253	797.0	COG2936@1|root,COG2936@2|Bacteria,1ZTD6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_398588_1	1121272.KB903249_gene1700	1.232e-94	331.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2GJYH@201174|Actinobacteria,4DBUI@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
WZS1_k127_4007133_7	379066.GAU_1277	1.156e-16	85.0	COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria,1ZT9A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EG	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
WZS1_k127_4007133_6	926550.CLDAP_28250	1.079e-27	124.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WZS1_k127_4007133_5	243365.CV_3711	1.03e-37	146.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,2VU7V@28216|Betaproteobacteria,2KT7C@206351|Neisseriales	206351|Neisseriales	J	Translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
WZS1_k127_4007133_3	269799.Gmet_3460	2.444e-90	320.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS1_k127_4007133_1	1123368.AUIS01000024_gene949	8.971e-115	394.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2NBU9@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS1_k127_4007133_0	1123368.AUIS01000024_gene948	6.898e-122	398.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2NCCI@225057|Acidithiobacillales	225057|Acidithiobacillales	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WZS1_k127_4007133_2	1123368.AUIS01000024_gene947	2.502e-99	330.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,1RMM4@1236|Gammaproteobacteria,2NDPN@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS1_k127_4007133_4	1123368.AUIS01000024_gene946	5.72e-81	290.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,1RS3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Secretion protein	yhiI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WZS1_k127_4007133_8	550540.Fbal_3456	7.903e-09	65.0	COG1538@1|root,COG1538@2|Bacteria,1N23P@1224|Proteobacteria,1RMXN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WZS1_k127_4012028_3	861299.J421_1756	1.795e-13	71.0	COG0624@1|root,COG0624@2|Bacteria,1ZUA4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_4012028_0	861299.J421_0308	2.368e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,1ZTP3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS1_k127_4012028_2	379066.GAU_2818	8.787e-14	81.0	298U8@1|root,2ZVYE@2|Bacteria,1ZUU9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4012028_1	1379270.AUXF01000001_gene2496	1.233e-37	153.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WZS1_k127_4016311_3	1047013.AQSP01000120_gene970	1.391e-23	106.0	COG2367@1|root,COG2367@2|Bacteria,2NQ4B@2323|unclassified Bacteria	2|Bacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
WZS1_k127_4016311_4	1232410.KI421412_gene421	1.297e-06	55.0	2EBKH@1|root,335KX@2|Bacteria,1NAWH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4016311_5	196490.AUEZ01000039_gene7044	9.331e-05	53.0	COG3554@1|root,COG3554@2|Bacteria,1RHFQ@1224|Proteobacteria,2U9RI@28211|Alphaproteobacteria,3JU9E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4016311_1	215803.DB30_7372	4.995e-50	196.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,43BIG@68525|delta/epsilon subdivisions,2X6WU@28221|Deltaproteobacteria,2Z3DE@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
WZS1_k127_4016311_0	1379270.AUXF01000007_gene1064	2.071e-66	241.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
WZS1_k127_4016311_2	1379270.AUXF01000007_gene1063	2.161e-46	179.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
WZS1_k127_4018151_0	1198452.Jab_1c22590	2.395e-101	344.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VRVE@28216|Betaproteobacteria,475TS@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_4018151_3	309801.trd_A0609	8.977e-05	49.0	COG2353@1|root,COG2353@2|Bacteria,2G73S@200795|Chloroflexi,27Z4A@189775|Thermomicrobia	189775|Thermomicrobia	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WZS1_k127_4018151_2	1379270.AUXF01000002_gene1364	9.981e-15	78.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1364|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4018151_1	1379270.AUXF01000002_gene1364	1.733e-45	179.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1364|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4028859_3	1150600.ADIARSV_0366	4.349e-75	258.0	COG1680@1|root,COG1680@2|Bacteria,4NFUI@976|Bacteroidetes,1INWP@117747|Sphingobacteriia	976|Bacteroidetes	V	COGs COG1680 Beta-lactamase class C and other penicillin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WZS1_k127_4028859_4	1121033.AUCF01000004_gene5013	1.174e-39	160.0	COG3603@1|root,COG3603@2|Bacteria,1RI6G@1224|Proteobacteria,2UFGZ@28211|Alphaproteobacteria,2JZPN@204441|Rhodospirillales	204441|Rhodospirillales	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_7
WZS1_k127_4028859_0	518766.Rmar_1037	1.635e-149	488.0	COG0624@1|root,COG0624@2|Bacteria,4NEHJ@976|Bacteroidetes,1FIZ2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase family M28	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS1_k127_4028859_2	1254432.SCE1572_08890	1.838e-87	305.0	COG0596@1|root,COG0596@2|Bacteria,1N5ZI@1224|Proteobacteria,43AI1@68525|delta/epsilon subdivisions,2X5Y9@28221|Deltaproteobacteria,2Z37K@29|Myxococcales	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS1_k127_4028859_1	234267.Acid_1969	1.645e-90	324.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria	2|Bacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_4034502_2	1122137.AQXF01000005_gene1070	3.568e-103	345.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2TU6T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WZS1_k127_4034502_0	234267.Acid_1953	0.0	1219.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4034502_5	861299.J421_4451	5.161e-58	212.0	COG0590@1|root,COG0590@2|Bacteria	2|Bacteria	FJ	tRNA wobble adenosine to inosine editing	guaD	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
WZS1_k127_4034502_1	234267.Acid_2282	6.452e-212	679.0	COG1228@1|root,COG1228@2|Bacteria,3Y3PQ@57723|Acidobacteria	57723|Acidobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_4034502_4	861299.J421_2098	6.751e-71	252.0	28M5H@1|root,2ZAJ9@2|Bacteria,1ZUWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4034502_3	187303.BN69_1574	6.985e-74	253.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2U7R3@28211|Alphaproteobacteria,36YI0@31993|Methylocystaceae	28211|Alphaproteobacteria	O	Glutathione peroxidase	MA20_01100	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WZS1_k127_4034502_7	926550.CLDAP_19560	3.337e-40	153.0	2EB0S@1|root,3351M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4034502_6	1122927.KB895416_gene3586	4.498e-53	192.0	COG2318@1|root,COG2318@2|Bacteria,1V6MV@1239|Firmicutes,4HH68@91061|Bacilli,26YC6@186822|Paenibacillaceae	91061|Bacilli	S	Squalene--hopene cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_4034502_8	13690.CP98_02831	4.664e-07	58.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRFP@28211|Alphaproteobacteria,2K5MF@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_4038214_4	861299.J421_2669	6.96e-106	353.0	COG0320@1|root,COG0320@2|Bacteria,1ZTA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WZS1_k127_4038214_6	485913.Krac_2551	1.198e-49	192.0	COG0665@1|root,COG0665@2|Bacteria,2G6QE@200795|Chloroflexi	200795|Chloroflexi	E	PFAM FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
WZS1_k127_4038214_7	1379270.AUXF01000005_gene516	2.671e-49	190.0	COG3170@1|root,COG3170@2|Bacteria,1ZTDF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
WZS1_k127_4038214_5	861299.J421_2674	1.686e-56	205.0	COG0463@1|root,COG0463@2|Bacteria,1ZTJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferase family 2	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	Glycos_transf_2
WZS1_k127_4038214_10	1379270.AUXF01000004_gene3124	4.758e-11	72.0	2FDPQ@1|root,345QV@2|Bacteria,1ZU3Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4038214_2	641524.ADICYQ_1612	2.687e-136	458.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,47JX4@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
WZS1_k127_4038214_8	316067.Geob_1155	2.106e-38	160.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,42NPQ@68525|delta/epsilon subdivisions,2WQ5U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
WZS1_k127_4038214_9	1379270.AUXF01000005_gene334	2.478e-35	147.0	COG1629@1|root,COG1629@2|Bacteria	2|Bacteria	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
WZS1_k127_4038214_1	1379270.AUXF01000005_gene335	2.07e-283	905.0	COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,1ZTBA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
WZS1_k127_4038214_3	1379270.AUXF01000005_gene336	2.465e-119	406.0	28PJE@1|root,2ZC90@2|Bacteria,1ZTV5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SusD_RagB
WZS1_k127_4038214_11	1307437.J139_00560	0.0002418	49.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,2Q4TG@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WZS1_k127_4038214_0	861299.J421_1753	5.23e-292	915.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
WZS1_k127_4059884_1	861299.J421_3626	6.677e-57	216.0	COG5557@1|root,COG5557@2|Bacteria,1ZTCE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4059884_4	761193.Runsl_2966	4.117e-16	87.0	COG2010@1|root,COG2010@2|Bacteria,4NKQI@976|Bacteroidetes,47PEX@768503|Cytophagia	976|Bacteroidetes	C	PFAM Cytochrome C	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
WZS1_k127_4059884_3	1379270.AUXF01000003_gene3824	2.931e-27	129.0	COG2010@1|root,COG2010@2|Bacteria,1ZTMS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
WZS1_k127_4059884_0	379066.GAU_2035	2.304e-168	539.0	COG5557@1|root,COG5557@2|Bacteria,1ZSN2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
WZS1_k127_4059884_2	861299.J421_3630	6.912e-36	138.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
WZS1_k127_4064519_1	1379270.AUXF01000004_gene2994	1.734e-107	356.0	COG0104@1|root,COG0104@2|Bacteria,1ZSNV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WZS1_k127_4064519_2	861299.J421_2803	3.448e-103	356.0	COG2805@1|root,COG2805@2|Bacteria,1ZT2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS1_k127_4064519_0	861299.J421_2799	6.425e-140	451.0	COG0180@1|root,COG0180@2|Bacteria,1ZT3P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WZS1_k127_4064519_3	1348657.M622_08145	5.241e-16	91.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,2KVHM@206389|Rhodocyclales	206389|Rhodocyclales	G	COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WZS1_k127_4065162_8	344747.PM8797T_16917	2.513e-62	239.0	COG0276@1|root,COG0276@2|Bacteria,2IX75@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
WZS1_k127_4065162_0	926550.CLDAP_19140	1.191e-155	530.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WZS1_k127_4065162_3	479434.Sthe_2327	4.431e-121	406.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,27XMR@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
WZS1_k127_4065162_1	479434.Sthe_2324	1.886e-137	445.0	COG0407@1|root,COG0407@2|Bacteria,2G5NU@200795|Chloroflexi,27XWH@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
WZS1_k127_4065162_9	661478.OP10G_0939	1.718e-46	176.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042597,GO:0044464,GO:0050587,GO:0051213,GO:0055114	1.13.11.49	ko:K09162	-	-	-	-	ko00000,ko01000	-	-	-	Chlor_dismutase
WZS1_k127_4065162_4	690850.Desaf_2643	1.603e-113	392.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,2M85A@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
WZS1_k127_4065162_10	429009.Adeg_1258	1.2e-43	177.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,42ES8@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
WZS1_k127_4065162_7	1125863.JAFN01000001_gene1122	1.774e-74	266.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
WZS1_k127_4065162_6	644966.Tmar_1263	3.248e-81	292.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3WDC1@538999|Clostridiales incertae sedis	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
WZS1_k127_4065162_5	671143.DAMO_0982	2.652e-109	366.0	COG0535@1|root,COG0535@2|Bacteria,2NQVH@2323|unclassified Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	pqqE	-	-	ko:K22226,ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
WZS1_k127_4065162_2	1550073.JROH01000009_gene1399	8.954e-135	447.0	COG4772@1|root,COG4772@2|Bacteria,1MWDG@1224|Proteobacteria,2U4AH@28211|Alphaproteobacteria,2K4W5@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K16091	-	-	-	-	ko00000,ko02000	1.B.14.1.14	-	-	Plug,TonB_dep_Rec
WZS1_k127_4079326_5	357808.RoseRS_2452	0.0001358	49.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi,37544@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20,fn3
WZS1_k127_4079326_3	1379270.AUXF01000003_gene3804	2.441e-47	190.0	COG2928@1|root,COG2928@2|Bacteria,1ZTMN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
WZS1_k127_4079326_2	861299.J421_1678	3.651e-70	251.0	COG0075@1|root,COG0075@2|Bacteria,1ZTF3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WZS1_k127_4079326_4	1408473.JHXO01000005_gene1511	1.18e-34	145.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,MerR_1
WZS1_k127_4079326_0	469383.Cwoe_5866	5.067e-141	455.0	COG1488@1|root,COG1488@2|Bacteria,2GJAT@201174|Actinobacteria,4CQTG@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,QRPTase_C,QRPTase_N
WZS1_k127_4079326_1	1379270.AUXF01000002_gene1837	2.562e-108	361.0	COG1446@1|root,COG1446@2|Bacteria,1ZTAQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Asparaginase	-	-	3.5.1.26	ko:K01444	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Asparaginase_2
WZS1_k127_4096750_1	1379698.RBG1_1C00001G1725	1.369e-60	214.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
WZS1_k127_4096750_2	861299.J421_0561	7.062e-29	124.0	2CDZB@1|root,3340J@2|Bacteria,1ZU24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4096750_0	1499967.BAYZ01000026_gene1563	8.122e-78	269.0	COG0687@1|root,COG0687@2|Bacteria,2NPSD@2323|unclassified Bacteria	2|Bacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
WZS1_k127_4107577_1	861299.J421_1859	9.849e-90	312.0	COG0475@1|root,COG0475@2|Bacteria,1ZTBI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WZS1_k127_4107577_2	379066.GAU_0275	6.38e-58	218.0	COG0025@1|root,COG0025@2|Bacteria,1ZTCR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4107577_0	379066.GAU_0146	8.069e-157	497.0	COG5276@1|root,COG5492@1|root,COG5276@2|Bacteria,COG5492@2|Bacteria,1ZU8T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WZS1_k127_4124927_2	1379270.AUXF01000006_gene175	3.788e-109	371.0	COG1702@1|root,COG1702@2|Bacteria,1ZSSD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
WZS1_k127_4124927_0	379066.GAU_1715	1.749e-207	661.0	COG0173@1|root,COG0173@2|Bacteria,1ZTFX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WZS1_k127_4124927_1	861299.J421_3358	9.841e-114	376.0	COG0820@1|root,COG0820@2|Bacteria,1ZTAJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
WZS1_k127_4124927_3	391625.PPSIR1_35862	2.469e-72	260.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WZS1_k127_4138711_1	1379270.AUXF01000002_gene1600	7.131e-60	211.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1600|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4138711_0	234267.Acid_1953	0.0	1040.0	COG4447@1|root,COG4447@2|Bacteria,3Y487@57723|Acidobacteria	57723|Acidobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4155682_3	518766.Rmar_0192	1.355e-52	188.0	COG0720@1|root,COG0720@2|Bacteria,4NNY0@976|Bacteroidetes,1FJAI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WZS1_k127_4155682_1	861299.J421_2704	1.235e-77	266.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WZS1_k127_4155682_2	861299.J421_2705	5.794e-62	229.0	COG4221@1|root,COG4221@2|Bacteria,1ZTPW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WZS1_k127_4155682_6	861299.J421_2706	3.369e-16	87.0	2FCPE@1|root,344SN@2|Bacteria,1ZU2F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4155682_0	880073.Calab_3204	2.012e-160	526.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
WZS1_k127_4155682_4	861299.J421_2711	1.398e-46	171.0	COG0457@1|root,COG0457@2|Bacteria,1ZTX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
WZS1_k127_4155682_5	861299.J421_2712	5.039e-46	173.0	COG2236@1|root,COG2236@2|Bacteria,1ZTQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
WZS1_k127_4160571_0	379066.GAU_0394	1.214e-162	519.0	COG0591@1|root,COG0591@2|Bacteria,1ZT93@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WZS1_k127_4160571_4	1123277.KB893228_gene2052	5.599e-102	365.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47TV8@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS1_k127_4160571_2	452637.Oter_3628	5.705e-129	423.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,3K7UU@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
WZS1_k127_4160571_3	234267.Acid_3960	8.861e-126	424.0	COG0111@1|root,COG0111@2|Bacteria,3Y7TQ@57723|Acidobacteria	57723|Acidobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS1_k127_4160571_1	1120985.AUMI01000011_gene435	1.583e-134	438.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4H26T@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WZS1_k127_4160571_5	1118054.CAGW01000005_gene3791	6.358e-83	293.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,26QYR@186822|Paenibacillaceae	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WZS1_k127_4174665_4	215803.DB30_0411	3.047e-33	135.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria,2YWK1@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_4174665_5	317619.ANKN01000074_gene3099	2.038e-13	76.0	COG0517@1|root,COG0517@2|Bacteria,1GDBW@1117|Cyanobacteria,1MP2K@1212|Prochloraceae	1117|Cyanobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WZS1_k127_4174665_3	1379270.AUXF01000001_gene1884	2.414e-43	172.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
WZS1_k127_4174665_0	1123242.JH636434_gene3744	3.321e-148	490.0	COG1574@1|root,COG1574@2|Bacteria,2IXY4@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS1_k127_4174665_1	861299.J421_3636	1.742e-126	440.0	2AEF2@1|root,314A1@2|Bacteria,1ZSNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
WZS1_k127_4174665_2	649747.HMPREF0083_05364	2.07e-55	197.0	COG2318@1|root,COG2318@2|Bacteria,1V2BI@1239|Firmicutes,4HF8B@91061|Bacilli,26XPE@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the metal hydrolase YfiT family	yfiT	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_4206842_1	1379270.AUXF01000001_gene1887	6.269e-186	591.0	COG1288@1|root,COG1288@2|Bacteria	2|Bacteria	S	antiporter activity	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
WZS1_k127_4206842_3	497964.CfE428DRAFT_4661	4.416e-22	112.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4206842_4	1122222.AXWR01000049_gene1616	2.065e-13	76.0	COG4914@1|root,COG4914@2|Bacteria,1WNGG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4206842_0	1173024.KI912148_gene4415	4.621e-251	792.0	COG2366@1|root,COG2366@2|Bacteria,1G0QT@1117|Cyanobacteria,1JK3D@1189|Stigonemataceae	1117|Cyanobacteria	S	Penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WZS1_k127_4206842_2	1403819.BATR01000027_gene881	1.049e-85	286.0	COG4948@1|root,COG4948@2|Bacteria,46VZI@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
WZS1_k127_4212193_5	379066.GAU_1554	9.852e-25	112.0	COG0195@1|root,COG0195@2|Bacteria,1ZSNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N
WZS1_k127_4212193_6	1125863.JAFN01000001_gene1427	6.125e-16	83.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
WZS1_k127_4212193_7	338966.Ppro_2157	1.827e-12	76.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4212193_4	379066.GAU_1552	1.147e-36	151.0	COG1496@1|root,COG1496@2|Bacteria,1ZTTT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WZS1_k127_4212193_0	379066.GAU_1551	2.943e-181	583.0	COG0766@1|root,COG0766@2|Bacteria,1ZSZ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WZS1_k127_4212193_3	861299.J421_3181	4.64e-82	286.0	28Q1P@1|root,2ZB8E@2|Bacteria,1ZSPA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
WZS1_k127_4212193_1	861299.J421_4340	3.852e-162	520.0	COG0520@1|root,COG0520@2|Bacteria,1ZSV8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WZS1_k127_4212193_2	1123368.AUIS01000005_gene390	3.689e-134	440.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,2NC7U@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WZS1_k127_4234216_2	1125863.JAFN01000001_gene3520	3.66e-48	185.0	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,42SQA@68525|delta/epsilon subdivisions,2WP3P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAD-superfamily hydrolase, subfamily IIB	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
WZS1_k127_4234216_0	671143.DAMO_1541	9.164e-142	460.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
WZS1_k127_4234216_3	671143.DAMO_1538	1.649e-23	112.0	COG0668@1|root,COG0668@2|Bacteria,2NQ6B@2323|unclassified Bacteria	2|Bacteria	M	transmembrane transport	cmpX	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
WZS1_k127_4234216_1	330214.NIDE4207	1.195e-127	416.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
WZS1_k127_4249454_1	379066.GAU_1605	1.543e-95	319.0	COG0496@1|root,COG0496@2|Bacteria,1ZT6W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WZS1_k127_4249454_3	861299.J421_3240	7.014e-68	246.0	COG2518@1|root,COG2518@2|Bacteria,1ZTED@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WZS1_k127_4249454_2	909663.KI867149_gene3387	4.605e-85	291.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RCV@68525|delta/epsilon subdivisions,2WN35@28221|Deltaproteobacteria,2MR44@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
WZS1_k127_4249454_5	1121861.KB899912_gene980	1.962e-11	75.0	COG1254@1|root,COG1254@2|Bacteria,1PU46@1224|Proteobacteria,2UF7Z@28211|Alphaproteobacteria,2JTTR@204441|Rhodospirillales	204441|Rhodospirillales	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WZS1_k127_4249454_4	861299.J421_3244	1.411e-51	194.0	COG0253@1|root,COG0253@2|Bacteria,1ZU42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
WZS1_k127_4249454_0	1379270.AUXF01000006_gene276	1.414e-106	351.0	COG0463@1|root,COG0463@2|Bacteria,1ZT31@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WZS1_k127_4249454_6	1035197.HMPREF9999_00860	9.918e-06	57.0	COG4485@1|root,COG4485@2|Bacteria,4NEE5@976|Bacteroidetes,2FMKE@200643|Bacteroidia,1WD10@1283313|Alloprevotella	976|Bacteroidetes	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
WZS1_k127_4269634_4	1379270.AUXF01000002_gene1817	1.444e-11	67.0	COG0668@1|root,COG0668@2|Bacteria,1ZSU5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
WZS1_k127_4269634_1	450851.PHZ_c0370	4.579e-75	266.0	COG0739@1|root,COG0739@2|Bacteria,1MXH6@1224|Proteobacteria,2U25J@28211|Alphaproteobacteria,2KH12@204458|Caulobacterales	204458|Caulobacterales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WZS1_k127_4269634_0	861299.J421_4065	4.96e-219	699.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	choD	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_binding_2,GMC_oxred_C,GMC_oxred_N
WZS1_k127_4269634_2	411477.PARMER_02816	6.611e-43	179.0	COG1629@1|root,COG4771@2|Bacteria,4PMUZ@976|Bacteroidetes,2FMM0@200643|Bacteroidia,22ZTD@171551|Porphyromonadaceae	976|Bacteroidetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WZS1_k127_4269634_3	861299.J421_1643	2.162e-23	101.0	COG4447@1|root,COG4447@2|Bacteria,1ZT1T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WZS1_k127_4275061_1	760192.Halhy_0173	2.422e-303	957.0	COG0160@1|root,COG0739@1|root,COG2334@1|root,COG0160@2|Bacteria,COG0739@2|Bacteria,COG2334@2|Bacteria,4NFMP@976|Bacteroidetes,1IWK9@117747|Sphingobacteriia	976|Bacteroidetes	E	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
WZS1_k127_4275061_7	1408473.JHXO01000013_gene586	2.964e-06	58.0	COG4244@1|root,COG4244@2|Bacteria,4NPYK@976|Bacteroidetes,2FYNE@200643|Bacteroidia	976|Bacteroidetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
WZS1_k127_4275061_5	1379270.AUXF01000002_gene1720	3.513e-27	117.0	2D0AC@1|root,30PHJ@2|Bacteria,1ZUY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4275061_3	234267.Acid_2124	4.806e-90	313.0	COG0531@1|root,COG0531@2|Bacteria,3Y6HV@57723|Acidobacteria	57723|Acidobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WZS1_k127_4275061_0	861299.J421_6304	0.0	1219.0	COG4447@1|root,COG4447@2|Bacteria,1ZUBH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WZS1_k127_4275061_4	225937.HP15_3244	4.947e-70	254.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,1RR22@1236|Gammaproteobacteria,466G0@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
WZS1_k127_4275061_6	1280390.CBQR020000033_gene723	6.585e-15	78.0	2EGKD@1|root,33ACM@2|Bacteria,1VKRN@1239|Firmicutes,4HSEX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4275061_2	1379270.AUXF01000002_gene1364	1.08e-141	468.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1364|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4285709_0	861299.J421_2768	4.73e-181	581.0	COG0086@1|root,COG0086@2|Bacteria,1ZSZQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WZS1_k127_4285709_2	1379270.AUXF01000004_gene3046	4.156e-92	306.0	COG0086@1|root,COG0303@1|root,COG0086@2|Bacteria,COG0303@2|Bacteria,1ZSZQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WZS1_k127_4285709_1	379066.GAU_3920	1.137e-97	344.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,1ZTYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
WZS1_k127_4289636_3	1157637.KB892154_gene7418	6.771e-58	220.0	COG2303@1|root,COG2303@2|Bacteria,2GNHC@201174|Actinobacteria	201174|Actinobacteria	E	glucose-methanol-choline oxidoreductase	-	-	1.1.1.400	ko:K20927,ko:K21166	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
WZS1_k127_4289636_1	1379270.AUXF01000002_gene1185	1.888e-103	352.0	COG0486@1|root,COG0486@2|Bacteria,1ZSRA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WZS1_k127_4289636_2	861299.J421_1067	3.622e-98	347.0	COG0706@1|root,COG0706@2|Bacteria,1ZSKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
WZS1_k127_4289636_4	43989.cce_0746	1.056e-27	119.0	COG0759@1|root,COG0759@2|Bacteria,1G90B@1117|Cyanobacteria,3KIEZ@43988|Cyanothece	1117|Cyanobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
WZS1_k127_4289636_5	861299.J421_1069	3.178e-17	88.0	COG0594@1|root,COG0594@2|Bacteria,1ZV89@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WZS1_k127_4289636_7	861299.J421_1070	1.098e-16	81.0	COG0230@1|root,COG0230@2|Bacteria,1ZU59@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
WZS1_k127_4289636_0	379066.GAU_0001	9.222e-175	559.0	COG0593@1|root,COG0593@2|Bacteria,1ZSQ2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WZS1_k127_4289636_6	861299.J421_1072	9.005e-17	81.0	COG0592@1|root,COG0592@2|Bacteria,1ZT22@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_3
WZS1_k127_4296719_2	1125863.JAFN01000001_gene501	3.276e-22	106.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	3.4.21.10	ko:K01317	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	BatA,CARDB,F5_F8_type_C,HemolysinCabind,Laminin_G_3,NIDO,VWA_2
WZS1_k127_4296719_0	861299.J421_3749	2.022e-89	304.0	COG1721@1|root,COG1721@2|Bacteria,1ZT0H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WZS1_k127_4296719_1	666685.R2APBS1_2606	1.304e-41	160.0	COG0599@1|root,COG0599@2|Bacteria,1N38Z@1224|Proteobacteria,1S5G6@1236|Gammaproteobacteria,1X6C8@135614|Xanthomonadales	135614|Xanthomonadales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WZS1_k127_4300751_5	1297863.APJF01000038_gene1770	8.993e-20	90.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UFPQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
WZS1_k127_4300751_3	1121904.ARBP01000004_gene1102	5.58e-27	112.0	COG2261@1|root,COG2261@2|Bacteria,4NVBV@976|Bacteroidetes	976|Bacteroidetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WZS1_k127_4300751_4	926560.KE387027_gene824	2.178e-24	109.0	COG2318@1|root,COG2318@2|Bacteria,1WNBD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_4300751_0	1379698.RBG1_1C00001G1080	1.075e-167	554.0	COG2091@1|root,COG2091@2|Bacteria,2NQPA@2323|unclassified Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WZS1_k127_4300751_2	1449076.JOOE01000004_gene117	2.291e-35	139.0	COG0604@1|root,COG0604@2|Bacteria,1QY0U@1224|Proteobacteria	1224|Proteobacteria	C	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
WZS1_k127_4300751_1	1303518.CCALI_01109	2.39e-54	196.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
WZS1_k127_4320856_0	330214.NIDE3570	5.673e-111	371.0	COG2203@1|root,COG3437@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,3J10H@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
WZS1_k127_4320856_2	861299.J421_3958	5.868e-75	256.0	COG3871@1|root,COG3871@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyrid_ox_like
WZS1_k127_4320856_3	861299.J421_3902	5.993e-74	282.0	COG5587@1|root,COG5587@2|Bacteria,1ZTH8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
WZS1_k127_4320856_5	649638.Trad_2033	1.059e-19	106.0	COG2827@1|root,COG2827@2|Bacteria,1WNB9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	COGs COG2827 endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
WZS1_k127_4320856_1	1379270.AUXF01000003_gene3385	3.884e-108	371.0	COG3852@1|root,COG3852@2|Bacteria,1ZSYP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	PAS domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
WZS1_k127_4320856_4	1379270.AUXF01000003_gene3386	2.903e-63	236.0	COG2204@1|root,COG2204@2|Bacteria,1ZSRQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WZS1_k127_4323744_2	1379270.AUXF01000006_gene247	4.899e-28	114.0	COG0105@1|root,COG0105@2|Bacteria,1ZTTD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NDK	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
WZS1_k127_4323744_1	861299.J421_3275	5.618e-29	121.0	COG1399@1|root,COG1399@2|Bacteria,1ZTSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
WZS1_k127_4323744_4	379066.GAU_1641	8.105e-15	75.0	COG0333@1|root,COG0333@2|Bacteria,1ZU2M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal L32p protein family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WZS1_k127_4323744_0	861299.J421_3273	1.294e-83	291.0	COG0416@1|root,COG0416@2|Bacteria,1ZSN4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WZS1_k127_4323744_3	379066.GAU_1638	1.28e-24	113.0	COG0331@1|root,COG0331@2|Bacteria,1ZT40@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WZS1_k127_4345858_4	909663.KI867151_gene3008	1.197e-22	102.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria,2MR35@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
WZS1_k127_4345858_0	234267.Acid_4582	6.663e-286	896.0	COG2234@1|root,COG2234@2|Bacteria,3Y435@57723|Acidobacteria	57723|Acidobacteria	S	Transferrin receptor-like dimerisation domain	-	-	3.4.17.21	ko:K01301	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PA,Peptidase_M28,TFR_dimer
WZS1_k127_4345858_3	316274.Haur_3168	8.321e-87	297.0	COG0491@1|root,COG0491@2|Bacteria,2GAIA@200795|Chloroflexi,376BC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS1_k127_4345858_2	1144275.COCOR_07436	1.425e-145	470.0	COG3239@1|root,COG3239@2|Bacteria,1QKDT@1224|Proteobacteria	1224|Proteobacteria	I	fatty acid desaturase	-	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
WZS1_k127_4345858_1	861299.J421_0094	1.963e-189	597.0	COG0520@1|root,COG0520@2|Bacteria,1ZT1P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WZS1_k127_4346483_2	861299.J421_3625	1.009e-39	154.0	COG3118@1|root,COG3118@2|Bacteria,1ZV4B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Thioredoxin-like domain	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
WZS1_k127_4346483_1	383372.Rcas_3776	1.471e-43	173.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi,3779C@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WZS1_k127_4346483_0	221288.JH992901_gene487	4.428e-88	302.0	COG0778@1|root,COG0778@2|Bacteria,1G5XK@1117|Cyanobacteria,1JKRX@1189|Stigonemataceae	1117|Cyanobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WZS1_k127_4346483_4	1168059.KB899087_gene2129	8.603e-13	70.0	2EGD6@1|root,33A4Z@2|Bacteria,1Q5G0@1224|Proteobacteria,2VBU7@28211|Alphaproteobacteria,3F1ZP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WZS1_k127_4346483_5	1122939.ATUD01000003_gene3520	2.485e-11	73.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	uspA4	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	Usp
WZS1_k127_4346483_3	1463936.JOJI01000173_gene6377	9.293e-36	141.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3
WZS1_k127_4364534_0	426117.M446_0777	2.651e-135	439.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,1JXTM@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WZS1_k127_4364534_2	1244869.H261_22103	6.058e-36	153.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2U2ZN@28211|Alphaproteobacteria,2JSJS@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
WZS1_k127_4364534_1	861299.J421_3936	3.97e-51	198.0	COG1409@1|root,COG1409@2|Bacteria,1ZTQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WZS1_k127_4379314_0	861299.J421_6282	1.108e-267	842.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
WZS1_k127_4389950_6	1382359.JIAL01000001_gene1432	4.044e-07	61.0	COG0768@1|root,COG0768@2|Bacteria,3Y3MX@57723|Acidobacteria,2JHRD@204432|Acidobacteriia	204432|Acidobacteriia	M	Penicillin-binding protein, dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WZS1_k127_4389950_5	861299.J421_3396	1.661e-25	119.0	2CIX2@1|root,33ZZP@2|Bacteria,1ZTZK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
WZS1_k127_4389950_4	1379270.AUXF01000006_gene134	4.283e-35	147.0	COG1792@1|root,COG1792@2|Bacteria,1ZSYE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	rod shape-determining protein MreC	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WZS1_k127_4389950_0	861299.J421_3398	1.475e-189	595.0	COG1077@1|root,COG1077@2|Bacteria,1ZT9B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Hsp70 protein	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WZS1_k127_4389950_2	46429.BV95_02568	2.268e-57	202.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2K4E7@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WZS1_k127_4389950_1	861299.J421_3399	5.134e-172	547.0	COG0686@1|root,COG0686@2|Bacteria,1ZSSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WZS1_k127_4389950_3	861299.J421_3400	1.45e-43	165.0	COG0612@1|root,COG0612@2|Bacteria,1ZSPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS1_k127_4391556_0	1379270.AUXF01000004_gene3069	2.361e-79	275.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
WZS1_k127_4391556_1	391037.Sare_1668	3.638e-05	56.0	28IHU@1|root,2Z8J0@2|Bacteria,2IAYX@201174|Actinobacteria,4DHI4@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF3103)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3103
WZS1_k127_4392822_0	1379270.AUXF01000003_gene3614	8.671e-212	694.0	COG1629@1|root,COG4771@2|Bacteria,1ZUBX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
WZS1_k127_4392822_2	269482.Bcep1808_2699	6.609e-52	195.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2VHG4@28216|Betaproteobacteria,1K19R@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
WZS1_k127_4392822_1	1210884.HG799476_gene15392	4.005e-95	325.0	COG3483@1|root,COG3483@2|Bacteria,2J412@203682|Planctomycetes	203682|Planctomycetes	E	Tryptophan 2,3-dioxygenase	-	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
WZS1_k127_4392822_3	380358.XALC_1754	4.04e-38	147.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,1RPY3@1236|Gammaproteobacteria,1X3FQ@135614|Xanthomonadales	135614|Xanthomonadales	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WZS1_k127_4393240_6	622637.KE124774_gene1454	3.135e-08	55.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2TSB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	arylsulfatase A	aslA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
WZS1_k127_4393240_7	566466.NOR53_512	0.0001307	48.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,1RN2V@1236|Gammaproteobacteria,1J88Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
WZS1_k127_4393240_2	861299.J421_3797	7.548e-61	226.0	COG0470@1|root,COG0470@2|Bacteria,1ZT21@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
WZS1_k127_4393240_3	1211115.ALIQ01000208_gene3363	5.018e-46	175.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,3NB3D@45404|Beijerinckiaceae	28211|Alphaproteobacteria	H	MoaC family	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
WZS1_k127_4393240_4	1379270.AUXF01000003_gene3651	1.768e-36	147.0	COG0741@1|root,COG0741@2|Bacteria,1ZTV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
WZS1_k127_4393240_0	379066.GAU_2228	2.639e-74	269.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1ZSX0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
WZS1_k127_4393240_5	861299.J421_3801	7.273e-11	68.0	2960H@1|root,2ZTB5@2|Bacteria,1ZU7H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4393240_1	378806.STAUR_0277	2.637e-69	246.0	COG2367@1|root,COG2367@2|Bacteria,1Q2UC@1224|Proteobacteria,438GK@68525|delta/epsilon subdivisions,2X3RE@28221|Deltaproteobacteria,2YWXF@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
WZS1_k127_4403995_0	550540.Fbal_2523	6.902e-40	166.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,1T462@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
WZS1_k127_4403995_1	243090.RB4278	2.341e-14	86.0	COG1633@1|root,COG4447@1|root,COG1633@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	AurF,Ferritin-like,Sortilin-Vps10
WZS1_k127_4449565_7	1123277.KB893180_gene2468	4.869e-06	49.0	COG2367@1|root,COG2367@2|Bacteria,4NE3C@976|Bacteroidetes,47M1M@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase enzyme family	per1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
WZS1_k127_4449565_5	379066.GAU_0401	1.187e-36	155.0	COG1416@1|root,COG1416@2|Bacteria,1ZUE6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4449565_2	861299.J421_4078	3.115e-54	199.0	COG1416@1|root,COG1416@2|Bacteria,1ZUE6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4449565_3	1089550.ATTH01000001_gene2218	2.635e-49	187.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WZS1_k127_4449565_4	861299.J421_3884	1.048e-41	173.0	COG1595@1|root,COG1595@2|Bacteria,1ZV3I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS1_k127_4449565_1	203124.Tery_1515	3.02e-105	356.0	COG4299@1|root,COG4299@2|Bacteria,1G087@1117|Cyanobacteria,1H86P@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
WZS1_k127_4449565_0	760192.Halhy_2510	8.232e-193	636.0	COG1913@1|root,COG1913@2|Bacteria,4PMAZ@976|Bacteroidetes,1IRBZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
WZS1_k127_4466053_7	694569.D7S_01548	7.418e-88	310.0	COG1495@1|root,COG1495@2|Bacteria,1R9CU@1224|Proteobacteria,1S3F9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	bond formation protein DsbB	-	-	-	-	-	-	-	-	-	-	-	-	DsbB
WZS1_k127_4466053_11	1123368.AUIS01000024_gene944	1.227e-18	97.0	COG3170@1|root,COG3170@2|Bacteria,1QDEM@1224|Proteobacteria,1S884@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Protein of unknown function (DUF1207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1207
WZS1_k127_4466053_8	861299.J421_0690	2.736e-83	280.0	2AYX9@1|root,31R2Z@2|Bacteria,1ZTNZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_4466053_5	1267535.KB906767_gene4657	5.031e-138	452.0	COG3852@1|root,COG3852@2|Bacteria,3Y3JR@57723|Acidobacteria,2JIY1@204432|Acidobacteriia	204432|Acidobacteriia	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
WZS1_k127_4466053_2	926560.KE387023_gene1698	1.476e-203	649.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1WM1W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KOT	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Response_reg
WZS1_k127_4466053_13	429009.Adeg_0418	2.326e-07	55.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26,HTH_3
WZS1_k127_4466053_1	518766.Rmar_1363	1.968e-270	856.0	COG0438@1|root,COG0438@2|Bacteria,4NEW7@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WZS1_k127_4466053_4	1499967.BAYZ01000036_gene2419	8.053e-148	485.0	COG2152@1|root,COG2152@2|Bacteria,2NPB8@2323|unclassified Bacteria	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
WZS1_k127_4466053_6	1121878.AUGL01000002_gene2303	4.526e-93	321.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,1RQ0T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS1_k127_4466053_0	1379270.AUXF01000001_gene1905	2.117e-279	867.0	COG0405@1|root,COG0405@2|Bacteria,1ZUCB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WZS1_k127_4466053_10	1114964.L485_19165	3.436e-34	147.0	COG0438@1|root,COG0438@2|Bacteria,1REXY@1224|Proteobacteria,2UHXS@28211|Alphaproteobacteria,2K5WM@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
WZS1_k127_4466053_3	330084.JNYZ01000006_gene1286	1.354e-156	515.0	COG2303@1|root,COG2303@2|Bacteria,2GJAU@201174|Actinobacteria,4DX8R@85010|Pseudonocardiales	201174|Actinobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WZS1_k127_4466053_12	997346.HMPREF9374_2356	1.376e-18	98.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HC0R@91061|Bacilli,27B9H@186824|Thermoactinomycetaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369,1.1.1.371	ko:K00010,ko:K16044	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951,R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WZS1_k127_4466053_14	509190.Cseg_1803	0.0002804	50.0	COG1917@1|root,COG1917@2|Bacteria,1RCXV@1224|Proteobacteria,2U6MY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WZS1_k127_4466053_9	1123024.AUII01000013_gene333	2.71e-70	239.0	COG3631@1|root,COG3631@2|Bacteria,2GR1G@201174|Actinobacteria,4EDKX@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WZS1_k127_4471158_3	861299.J421_1538	4.087e-58	211.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
WZS1_k127_4471158_1	518766.Rmar_1442	9.99e-144	471.0	COG0577@1|root,COG0577@2|Bacteria,4NECN@976|Bacteroidetes,1FIY8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS1_k127_4471158_0	518766.Rmar_1441	2.843e-154	497.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes	976|Bacteroidetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS1_k127_4471158_2	518766.Rmar_1440	9.005e-118	392.0	COG0845@1|root,COG0845@2|Bacteria,4NFT4@976|Bacteroidetes	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
WZS1_k127_4473306_2	379066.GAU_3732	2.144e-05	57.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WZS1_k127_4473306_1	861299.J421_0313	9.048e-184	609.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
WZS1_k127_4473306_0	1379270.AUXF01000005_gene643	4.774e-288	900.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZTF0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_4484066_3	1089551.KE386572_gene3676	1.986e-97	325.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria,4BPZG@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WZS1_k127_4484066_2	1089551.KE386572_gene3677	1.361e-114	386.0	COG0106@1|root,COG0139@1|root,COG0106@2|Bacteria,COG0139@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,4BQ2C@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
WZS1_k127_4484066_1	164328.Phyra95105	1.126e-116	398.0	COG0141@1|root,KOG2697@2759|Eukaryota,3QAS9@4776|Peronosporales	4776|Peronosporales	E	Histidinol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Histidinol_dh
WZS1_k127_4484066_5	1227488.C477_21870	7.636e-29	121.0	COG3439@1|root,arCOG02761@2157|Archaea,2Y1ZJ@28890|Euryarchaeota,23ZM2@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WZS1_k127_4484066_4	794903.OPIT5_05430	1.072e-60	221.0	COG1208@1|root,COG1208@2|Bacteria,46UYH@74201|Verrucomicrobia,3K75K@414999|Opitutae	414999|Opitutae	JM	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
WZS1_k127_4484066_6	292459.STH595	1.11e-07	63.0	2DR9X@1|root,33AUW@2|Bacteria	2|Bacteria	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
WZS1_k127_4484066_0	1122179.KB890441_gene1057	9.387e-227	716.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1IW3G@117747|Sphingobacteriia	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WZS1_k127_4489602_0	379066.GAU_1758	2.81e-146	479.0	COG0768@1|root,COG0768@2|Bacteria,1ZSX5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WZS1_k127_4489602_1	379066.GAU_1757	1.26e-129	447.0	COG0772@1|root,COG0772@2|Bacteria,1ZSXM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Cell cycle protein	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WZS1_k127_4489602_2	379066.GAU_1756	6.488e-111	366.0	COG0777@1|root,COG0777@2|Bacteria,1ZSSK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WZS1_k127_4489602_3	379066.GAU_1755	1.137e-72	259.0	COG0285@1|root,COG0285@2|Bacteria,1ZSRP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
WZS1_k127_4512306_2	1502850.FG91_02453	1.136e-34	135.0	28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,2U5RX@28211|Alphaproteobacteria,2K5KG@204457|Sphingomonadales	204457|Sphingomonadales	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
WZS1_k127_4512306_3	869213.JCM21142_52364	1.245e-33	141.0	COG0739@1|root,COG0739@2|Bacteria,4NGHH@976|Bacteroidetes,47QTZ@768503|Cytophagia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WZS1_k127_4512306_0	635013.TherJR_0722	2.96e-79	279.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia,2606M@186807|Peptococcaceae	186801|Clostridia	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WZS1_k127_4512306_1	484019.THA_1343	2.764e-47	184.0	COG1228@1|root,COG1228@2|Bacteria,2GCDV@200918|Thermotogae	200918|Thermotogae	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_4529015_0	1089553.Tph_c09340	3.454e-222	712.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,42EPB@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WZS1_k127_4535059_1	204669.Acid345_1822	9.054e-72	246.0	COG4992@1|root,COG4992@2|Bacteria,3Y40B@57723|Acidobacteria,2JHYT@204432|Acidobacteriia	204432|Acidobacteriia	E	TIGRFAM ornithine aminotransferase	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
WZS1_k127_4535059_0	56107.Cylst_1084	1.928e-88	310.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria,1HKZ8@1161|Nostocales	1117|Cyanobacteria	EGP	major facilitator superfamily MFS_1	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
WZS1_k127_4564145_2	378806.STAUR_0277	6.734e-32	129.0	COG2367@1|root,COG2367@2|Bacteria,1Q2UC@1224|Proteobacteria,438GK@68525|delta/epsilon subdivisions,2X3RE@28221|Deltaproteobacteria,2YWXF@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
WZS1_k127_4564145_0	644966.Tmar_2150	8.691e-106	350.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,3WDJY@538999|Clostridiales incertae sedis	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WZS1_k127_4564145_3	330214.NIDE3177	0.0007702	51.0	COG0484@1|root,COG1948@1|root,COG0484@2|Bacteria,COG1948@2|Bacteria	2|Bacteria	L	resolution of meiotic recombination intermediates	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,ERCC4,Lsr2
WZS1_k127_4564145_1	379066.GAU_2655	4.95e-35	143.0	2DMMP@1|root,32SHG@2|Bacteria,1ZUUC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4571622_2	861299.J421_3532	5.186e-45	186.0	COG2045@1|root,COG2045@2|Bacteria,1ZTM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
WZS1_k127_4571622_0	1120973.AQXL01000127_gene2738	1.217e-186	601.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli,277WZ@186823|Alicyclobacillaceae	91061|Bacilli	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WZS1_k127_4571622_1	1379270.AUXF01000006_gene35	4.773e-61	214.0	COG2805@1|root,COG2805@2|Bacteria,1ZU8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS1_k127_4588163_0	379066.GAU_0579	2.123e-90	306.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1ZSP0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	DM	Chain length determinant protein	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	GNVR
WZS1_k127_4588163_3	158500.BV97_05581	7.859e-24	115.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2KCJS@204457|Sphingomonadales	204457|Sphingomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WZS1_k127_4588163_1	379066.GAU_0580	2.916e-25	115.0	COG1596@1|root,COG1596@2|Bacteria,1ZTXZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	polysaccharide export	-	-	-	-	-	-	-	-	-	-	-	-	SLBB
WZS1_k127_4588163_2	379066.GAU_0585	4.4e-24	106.0	COG2148@1|root,COG2148@2|Bacteria,1ZSW2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
WZS1_k127_4589785_5	1379270.AUXF01000001_gene1907	2.235e-18	94.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL,SnoaL_2
WZS1_k127_4589785_4	379066.GAU_0953	3.355e-41	162.0	2BBQ7@1|root,3258A@2|Bacteria,1ZUVG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4589785_6	1210884.HG799468_gene13635	2.09e-16	92.0	2E2CP@1|root,32XHN@2|Bacteria,2J0IA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4589785_1	1379270.AUXF01000007_gene1042	2.658e-121	398.0	COG4257@1|root,COG4257@2|Bacteria,1ZUIM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
WZS1_k127_4589785_2	887062.HGR_00015	1.067e-56	203.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2VQM1@28216|Betaproteobacteria,4ADKG@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM GCN5-related N-acetyltransferase	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
WZS1_k127_4589785_0	414684.RC1_3136	2.682e-167	543.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2JRAY@204441|Rhodospirillales	204441|Rhodospirillales	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS1_k127_4589785_3	671143.DAMO_2789	1.088e-44	164.0	COG2070@1|root,COG2070@2|Bacteria,2NQQC@2323|unclassified Bacteria	2|Bacteria	S	2-Nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
WZS1_k127_4626903_0	584708.Apau_0241	2.761e-118	403.0	COG3383@1|root,COG3383@2|Bacteria,3TAJC@508458|Synergistetes	508458|Synergistetes	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
WZS1_k127_4626903_1	861299.J421_2615	1.025e-27	124.0	COG4123@1|root,COG4123@2|Bacteria,1ZTJ4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4676059_5	1379270.AUXF01000001_gene2701	1.901e-49	193.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
WZS1_k127_4676059_2	1379270.AUXF01000001_gene2702	1.626e-133	445.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
WZS1_k127_4676059_0	1379270.AUXF01000001_gene2703	0.0	1375.0	COG3696@1|root,COG3696@2|Bacteria,1ZUQD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Protein export membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WZS1_k127_4676059_6	1122179.KB890480_gene3092	9.107e-45	184.0	COG5266@1|root,COG5266@2|Bacteria,4NI88@976|Bacteroidetes	976|Bacteroidetes	P	Domain of unknown function (DUF4198)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4198
WZS1_k127_4676059_3	530564.Psta_2977	1.621e-113	375.0	COG1082@1|root,COG1082@2|Bacteria,2IWZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
WZS1_k127_4676059_4	1303518.CCALI_00782	5.084e-54	208.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
WZS1_k127_4676059_7	596154.Alide2_1373	8.479e-12	79.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,4AA8I@80864|Comamonadaceae	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	nosX	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WZS1_k127_4676059_1	204669.Acid345_2395	2.902e-162	534.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
WZS1_k127_4700817_0	869210.Marky_0500	1.445e-89	302.0	COG2133@1|root,COG2133@2|Bacteria,1WJQY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Glucose Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WZS1_k127_4700817_1	379066.GAU_0477	2.605e-85	301.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WZS1_k127_4700817_2	1458427.BAWN01000012_gene707	2.52e-25	116.0	COG0730@1|root,COG0730@2|Bacteria,1RBHH@1224|Proteobacteria,2VU9J@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WZS1_k127_4702080_5	861299.J421_3270	5.008e-80	272.0	COG1028@1|root,COG1028@2|Bacteria,1ZT4H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS1_k127_4702080_7	379066.GAU_1636	6.484e-27	111.0	COG0236@1|root,COG0236@2|Bacteria,1ZU0X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WZS1_k127_4702080_2	379066.GAU_1635	1.567e-158	514.0	COG0304@1|root,COG0304@2|Bacteria,1ZSPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WZS1_k127_4702080_1	1379270.AUXF01000006_gene256	9.771e-161	514.0	COG1060@1|root,COG1060@2|Bacteria,1ZSRJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
WZS1_k127_4702080_4	379066.GAU_1633	2.373e-82	284.0	COG1427@1|root,COG1427@2|Bacteria,1ZT6H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
WZS1_k127_4702080_0	861299.J421_3265	2.155e-169	537.0	COG1060@1|root,COG1060@2|Bacteria,1ZSU1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
WZS1_k127_4702080_6	861299.J421_3264	5.987e-48	177.0	COG0245@1|root,COG0245@2|Bacteria,1ZTM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
WZS1_k127_4702080_8	1074488.AGBX01000001_gene398	8.892e-08	64.0	COG0586@1|root,COG0586@2|Bacteria,2GN43@201174|Actinobacteria,4FBH2@85020|Dermabacteraceae	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WZS1_k127_4702080_3	861299.J421_3262	1.34e-108	374.0	COG4974@1|root,COG4974@2|Bacteria,1ZTAH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS1_k127_4723667_1	1379270.AUXF01000005_gene464	8.544e-226	709.0	COG4147@1|root,COG4147@2|Bacteria,1ZUA3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sodium:solute symporter family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
WZS1_k127_4723667_0	861299.J421_3706	7.301e-313	970.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1ZTCG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	CI	MaoC like domain	-	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,MaoC_dehydratas
WZS1_k127_4723667_2	234267.Acid_4440	2.455e-50	186.0	COG1073@1|root,COG1073@2|Bacteria,3Y91X@57723|Acidobacteria	57723|Acidobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4727790_2	1125863.JAFN01000001_gene357	0.0001104	48.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WZS1_k127_4727790_3	370438.PTH_1825	0.0002032	51.0	COG0762@1|root,COG0762@2|Bacteria,1URMB@1239|Firmicutes,24RBP@186801|Clostridia,2633K@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
WZS1_k127_4727790_1	1125863.JAFN01000001_gene2308	2.078e-16	89.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
WZS1_k127_4727790_0	231434.JQJH01000001_gene1693	0.0	1134.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3NAD0@45404|Beijerinckiaceae	28211|Alphaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WZS1_k127_4746297_1	1128421.JAGA01000003_gene3727	5.188e-124	403.0	COG0274@1|root,COG0274@2|Bacteria	2|Bacteria	F	deoxyribose-phosphate aldolase activity	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WZS1_k127_4746297_0	379066.GAU_3235	1.707e-266	840.0	COG2091@1|root,COG2091@2|Bacteria,1ZUGF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_478219_7	546414.Deide_17390	2.054e-17	85.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	slyA	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
WZS1_k127_478219_2	404589.Anae109_4065	1.185e-101	343.0	COG0702@1|root,COG0702@2|Bacteria,1N3GN@1224|Proteobacteria,43F3M@68525|delta/epsilon subdivisions,2X39K@28221|Deltaproteobacteria,2YUZE@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
WZS1_k127_478219_5	1169143.KB911034_gene993	1.429e-37	148.0	COG4313@1|root,COG4313@2|Bacteria,1PRCN@1224|Proteobacteria,2VQHT@28216|Betaproteobacteria,1K45B@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
WZS1_k127_478219_3	1242864.D187_001573	1.138e-84	282.0	28S0M@1|root,2ZECI@2|Bacteria,1R0DG@1224|Proteobacteria,43CW2@68525|delta/epsilon subdivisions,2X842@28221|Deltaproteobacteria,2Z3KE@29|Myxococcales	28221|Deltaproteobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_478219_4	379066.GAU_2436	1.741e-44	168.0	COG0622@1|root,COG0622@2|Bacteria,1ZTSV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
WZS1_k127_478219_6	454957.IA64_19845	7.146e-26	123.0	COG2819@1|root,COG2819@2|Bacteria,1RB1X@1224|Proteobacteria,1S4AR@1236|Gammaproteobacteria,1X77Z@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
WZS1_k127_478219_1	204669.Acid345_3040	2.784e-130	432.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_478219_0	379066.GAU_2194	1.065e-155	496.0	COG0412@1|root,COG0412@2|Bacteria,1ZUKT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
WZS1_k127_478386_10	1379270.AUXF01000006_gene214	3.968e-66	231.0	COG0149@1|root,COG0149@2|Bacteria,1ZSYN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WZS1_k127_478386_16	379066.GAU_1676	1.283e-12	73.0	COG1314@1|root,COG1314@2|Bacteria,1ZTZS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
WZS1_k127_478386_2	379066.GAU_1675	2.757e-147	476.0	COG0505@1|root,COG0505@2|Bacteria,1ZT0T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
WZS1_k127_478386_12	861299.J421_3305	3.431e-46	169.0	COG0776@1|root,COG0776@2|Bacteria,1ZTTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WZS1_k127_478386_15	861299.J421_3304	1.925e-14	76.0	COG1977@1|root,COG1977@2|Bacteria,1ZU69@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WZS1_k127_478386_14	867903.ThesuDRAFT_00783	1.862e-35	140.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,24QVX@186801|Clostridia	186801|Clostridia	H	Molybdopterin converting factor subunit	-	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
WZS1_k127_478386_3	330214.NIDE1574	2.397e-121	399.0	COG2896@1|root,COG2896@2|Bacteria,3J0PB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Mob_synth_C,Radical_SAM
WZS1_k127_478386_11	349161.Dred_2332	1.379e-46	175.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,261SB@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WZS1_k127_478386_1	861299.J421_3301	1.312e-149	480.0	COG0039@1|root,COG0039@2|Bacteria,1ZSV3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
WZS1_k127_478386_8	1379270.AUXF01000006_gene222	7.211e-70	243.0	2CAZH@1|root,2Z7RU@2|Bacteria,1ZTQ9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
WZS1_k127_478386_0	316274.Haur_1733	0.0	1065.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WZS1_k127_478386_4	28444.JODQ01000003_gene4777	5.001e-118	384.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria,4EH4D@85012|Streptosporangiales	201174|Actinobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
WZS1_k127_478386_5	1223521.BBJX01000008_gene1385	1.896e-96	319.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,4AAK0@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
WZS1_k127_478386_13	1379270.AUXF01000006_gene229	1.308e-37	145.0	COG0838@1|root,COG0838@2|Bacteria,1ZTKK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WZS1_k127_478386_6	1379270.AUXF01000006_gene230	4.021e-91	309.0	COG0377@1|root,COG0377@2|Bacteria,1ZT85@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
WZS1_k127_478386_9	379066.GAU_1660	8.637e-67	243.0	COG0852@1|root,COG0852@2|Bacteria,1ZTCJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
WZS1_k127_478386_7	861299.J421_3292	1.161e-90	318.0	COG0649@1|root,COG0649@2|Bacteria,1ZSV6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
WZS1_k127_4821365_2	1379270.AUXF01000003_gene3507	6.135e-17	92.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1ZT7U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,Guanylate_cyc
WZS1_k127_4821365_1	861299.J421_3866	3.037e-75	280.0	2EWAK@1|root,33PPB@2|Bacteria,1ZT00@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4821365_0	861299.J421_3864	2.654e-134	451.0	COG2804@1|root,COG2804@2|Bacteria,1ZT2F@142182|Gemmatimonadetes	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
WZS1_k127_4831078_0	379066.GAU_0608	4.395e-95	334.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WZS1_k127_4831078_1	861299.J421_2339	2.062e-23	115.0	COG2911@1|root,COG2911@2|Bacteria,1ZT97@142182|Gemmatimonadetes	2|Bacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
WZS1_k127_4842133_1	861299.J421_3839	8.898e-76	260.0	COG0572@1|root,COG0572@2|Bacteria,1ZSM3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Cytidylate kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WZS1_k127_4842133_0	518766.Rmar_0272	1.011e-261	823.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
WZS1_k127_4856873_0	1192034.CAP_1547	3.528e-150	488.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,42STW@68525|delta/epsilon subdivisions,2WPBB@28221|Deltaproteobacteria,2YUQE@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.18	ko:K01439,ko:K13049	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS1_k127_4856873_2	243231.GSU0119	1.976e-22	106.0	COG0346@1|root,COG0346@2|Bacteria,1NPMU@1224|Proteobacteria	1224|Proteobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WZS1_k127_4856873_1	266117.Rxyl_3164	5.671e-59	221.0	COG0614@1|root,COG0614@2|Bacteria,2GM6R@201174|Actinobacteria,4CQ1N@84995|Rubrobacteria	84995|Rubrobacteria	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WZS1_k127_4872227_4	1274374.CBLK010000051_gene2124	5.414e-24	102.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,4H9PW@91061|Bacilli,26SJE@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08945	DHBP_synthase,GTP_cyclohydro2
WZS1_k127_4872227_2	1304874.JAFY01000007_gene2421	2.125e-36	145.0	COG0054@1|root,COG0054@2|Bacteria,3TAV8@508458|Synergistetes	508458|Synergistetes	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
WZS1_k127_4872227_3	861299.J421_3118	1.146e-24	109.0	COG0781@1|root,COG0781@2|Bacteria,1ZTRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WZS1_k127_4872227_0	861299.J421_3119	6.166e-117	390.0	COG0438@1|root,COG0438@2|Bacteria,1ZTBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WZS1_k127_4872227_1	379066.GAU_1477	5.329e-115	379.0	COG1493@1|root,COG1493@2|Bacteria,1ZSY3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
WZS1_k127_4872227_5	379066.GAU_1478	2.87e-07	62.0	COG2893@1|root,COG2893@2|Bacteria,1ZU41@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	PTS system fructose IIA component	-	-	-	ko:K02744	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
WZS1_k127_4881844_4	925775.XVE_3157	1.561e-36	144.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,1T1M4@1236|Gammaproteobacteria,1XAT6@135614|Xanthomonadales	135614|Xanthomonadales	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS1_k127_4881844_0	1297742.A176_00264	1.939e-163	526.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2Z2X4@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
WZS1_k127_4881844_5	589865.DaAHT2_0235	3.937e-14	80.0	COG2204@1|root,COG2204@2|Bacteria,1R13G@1224|Proteobacteria,42Y0M@68525|delta/epsilon subdivisions,2WTGU@28221|Deltaproteobacteria,2MMAV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WZS1_k127_4881844_6	861299.J421_1588	4.863e-14	83.0	COG0745@1|root,COG0745@2|Bacteria,1ZUUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS1_k127_4881844_1	477974.Daud_1728	1.561e-110	387.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG3605@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
WZS1_k127_4881844_3	1123508.JH636449_gene7421	3.183e-49	179.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WZS1_k127_4881844_2	706587.Desti_0852	3.344e-57	204.0	COG2203@1|root,COG4191@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,43BYI@68525|delta/epsilon subdivisions,2X79E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
WZS1_k127_4885688_7	234267.Acid_3225	3.823e-27	119.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
WZS1_k127_4885688_12	1112212.JH584235_gene3621	0.0009165	42.0	COG5002@1|root,COG5002@2|Bacteria,1QUGI@1224|Proteobacteria	1224|Proteobacteria	T	signal transduction Histidine kinase	cpxA	-	2.7.13.3	ko:K07640,ko:K19609	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728,M00770	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CpxA_peri,HAMP,HATPase_c,HK_sensor,HisKA
WZS1_k127_4885688_0	1123054.KB907703_gene1342	3.627e-112	379.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,1RRGY@1236|Gammaproteobacteria,1WVVW@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
WZS1_k127_4885688_3	1379270.AUXF01000001_gene2066	5.552e-71	258.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS1_k127_4885688_10	1125863.JAFN01000001_gene3054	7.551e-12	79.0	COG1413@1|root,COG1413@2|Bacteria,1NR1B@1224|Proteobacteria	1224|Proteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
WZS1_k127_4885688_5	861299.J421_0907	4.109e-55	200.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS1_k127_4885688_11	413816.BBJP01000039_gene2463	4.419e-09	66.0	COG3046@1|root,arCOG02839@2157|Archaea,2XTMY@28890|Euryarchaeota,23UFH@183963|Halobacteria	183963|Halobacteria	S	protein related to deoxyribodipyrimidine photolyase	phr4	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
WZS1_k127_4885688_6	1120792.JAFV01000001_gene1505	1.271e-33	137.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,36X71@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	phrB	GO:0000166,GO:0000719,GO:0003674,GO:0003824,GO:0003913,GO:0003914,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP,FAD_binding_7
WZS1_k127_4885688_2	404589.Anae109_3007	2.766e-99	341.0	COG0415@1|root,COG0415@2|Bacteria,1RG4D@1224|Proteobacteria,42NWP@68525|delta/epsilon subdivisions,2WJUA@28221|Deltaproteobacteria,2YUE6@29|Myxococcales	28221|Deltaproteobacteria	L	Deoxyribodipyrimidine photo-lyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
WZS1_k127_4885688_9	313612.L8106_15650	1.518e-14	87.0	COG1943@1|root,COG1943@2|Bacteria,1G5Z6@1117|Cyanobacteria,1HBEU@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WZS1_k127_4885688_1	379066.GAU_2695	2.625e-106	352.0	COG1234@1|root,COG1234@2|Bacteria,1ZTG7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WZS1_k127_4885688_8	861299.J421_2704	8.152e-22	99.0	COG0302@1|root,COG0302@2|Bacteria,1ZT6I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WZS1_k127_4885688_4	1280949.HAD_15357	2.288e-60	211.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria,43WRV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	fadA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS1_k127_489563_0	1379270.AUXF01000001_gene2148	1.625e-170	543.0	COG1473@1|root,COG1473@2|Bacteria,1ZSTC@142182|Gemmatimonadetes	2|Bacteria	S	Peptidase dimerisation domain	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_4896298_0	1248916.ANFY01000011_gene1053	5.056e-98	329.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2KA1X@204457|Sphingomonadales	204457|Sphingomonadales	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS1_k127_4896298_2	159087.Daro_2089	1.128e-82	280.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,2KW21@206389|Rhodocyclales	206389|Rhodocyclales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WZS1_k127_4896298_1	1283299.AUKG01000001_gene1281	6.556e-83	281.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4CPG1@84995|Rubrobacteria	84995|Rubrobacteria	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,Biotin_lipoyl,E1_dh,E3_binding,OxoGdeHyase_C,Transket_pyr
WZS1_k127_4905532_2	1267533.KB906739_gene2607	5.853e-05	54.0	COG1216@1|root,COG1216@2|Bacteria,3Y5XG@57723|Acidobacteria,2JK4J@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
WZS1_k127_4905532_0	1340493.JNIF01000003_gene2252	4.264e-90	312.0	COG2942@1|root,COG2942@2|Bacteria	2|Bacteria	G	2-epimerase	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
WZS1_k127_4927144_0	1379270.AUXF01000001_gene2611	1.252e-08	59.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF_2,GerE,PocR,Response_reg
WZS1_k127_4927144_1	1479235.KK366039_gene845	2.512e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,1T292@1236|Gammaproteobacteria,1XJYC@135619|Oceanospirillales	135619|Oceanospirillales	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16,TPR_19,TPR_8
WZS1_k127_4934328_2	903818.KI912268_gene1834	4.78e-86	289.0	COG1294@1|root,COG1294@2|Bacteria,3Y3UT@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome d ubiquinol oxidase, subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
WZS1_k127_4934328_0	1121920.AUAU01000018_gene1829	4.904e-207	651.0	COG1271@1|root,COG1271@2|Bacteria,3Y44V@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
WZS1_k127_4934328_5	1198452.Jab_2c26040	2.155e-17	84.0	COG5460@1|root,COG5460@2|Bacteria,1PTV0@1224|Proteobacteria,2W4JZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
WZS1_k127_4934328_3	323850.Shew_0933	4.979e-47	177.0	COG0500@1|root,COG2226@2|Bacteria,1PF9T@1224|Proteobacteria,1T9PG@1236|Gammaproteobacteria,2QDI5@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WZS1_k127_4934328_4	1198452.Jab_1c14310	1.907e-24	104.0	COG3324@1|root,COG3324@2|Bacteria,1PV09@1224|Proteobacteria,2VXYR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
WZS1_k127_4957436_2	653733.Selin_0517	2.246e-66	229.0	COG1272@1|root,COG1272@2|Bacteria	2|Bacteria	K	protein, Hemolysin III	hly3	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
WZS1_k127_4957436_3	1040982.AXAL01000024_gene6302	5.71e-23	106.0	2E69N@1|root,330XJ@2|Bacteria,1NM8X@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4957436_1	379066.GAU_2502	4.664e-67	248.0	COG2267@1|root,COG2267@2|Bacteria,1ZUNN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS1_k127_4957436_0	1385517.N800_08900	8.441e-155	498.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,1RZZ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4980286_5	83406.HDN1F_17130	5.441e-18	93.0	COG2402@1|root,COG2402@2|Bacteria,1NCFK@1224|Proteobacteria,1SRQ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
WZS1_k127_4980286_3	344747.PM8797T_25126	1.088e-44	175.0	COG3391@1|root,COG3391@2|Bacteria,2J2IQ@203682|Planctomycetes	203682|Planctomycetes	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
WZS1_k127_4980286_4	1379270.AUXF01000003_gene3430	5.475e-25	111.0	COG0712@1|root,COG0712@2|Bacteria,1ZTP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
WZS1_k127_4980286_6	290512.Paes_2245	1.793e-17	89.0	COG0711@1|root,COG0711@2|Bacteria,1FDW3@1090|Chlorobi	1090|Chlorobi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
WZS1_k127_4980286_7	595460.RRSWK_04830	6.406e-16	80.0	COG0636@1|root,COG0636@2|Bacteria,2J0QD@203682|Planctomycetes	203682|Planctomycetes	P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WZS1_k127_4980286_2	861299.J421_3947	1.804e-58	218.0	COG0356@1|root,COG0356@2|Bacteria,1ZSQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WZS1_k127_4980286_8	1510531.JQJJ01000009_gene727	0.0002392	47.0	COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria	1224|Proteobacteria	S	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
WZS1_k127_4980286_0	929562.Emtol_1558	1.017e-199	636.0	COG1228@1|root,COG1228@2|Bacteria,4NG0U@976|Bacteroidetes,47NDK@768503|Cytophagia	976|Bacteroidetes	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_4980286_1	1379270.AUXF01000002_gene1600	3.676e-101	334.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1600|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4985253_2	326427.Cagg_0669	5.876e-41	157.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_4985253_0	1519464.HY22_01095	2.332e-208	654.0	COG0538@1|root,COG0538@2|Bacteria	2|Bacteria	C	isocitrate dehydrogenase activity	icd	GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144	Iso_dh
WZS1_k127_4985253_1	1521187.JPIM01000189_gene828	4.278e-132	429.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi,374RX@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WZS1_k127_5000470_2	234267.Acid_5451	3.168e-59	218.0	COG0451@1|root,COG0451@2|Bacteria,3Y93E@57723|Acidobacteria	57723|Acidobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
WZS1_k127_5000470_1	1144275.COCOR_04256	1.376e-99	348.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5000470_0	861299.J421_0795	1.467e-107	355.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	2|Bacteria	H	Beta-eliminating lyase	bioF	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS1_k127_5012143_1	379066.GAU_3908	1.668e-08	66.0	COG5492@1|root,COG5492@2|Bacteria,1ZSW8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
WZS1_k127_5012143_0	886293.Sinac_2220	3.684e-109	363.0	COG2936@1|root,COG2936@2|Bacteria,2IY51@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_5047802_1	471854.Dfer_0095	1.347e-85	295.0	COG1680@1|root,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,47N9R@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
WZS1_k127_5047802_0	760192.Halhy_1321	2.041e-247	780.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1IVS2@117747|Sphingobacteriia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_5047802_2	1379270.AUXF01000002_gene1605	2.552e-69	244.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZSND@142182|Gemmatimonadetes	2|Bacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
WZS1_k127_5052588_0	1396418.BATQ01000168_gene1797	2.872e-184	588.0	COG1505@1|root,COG1505@2|Bacteria,46SRT@74201|Verrucomicrobia,2IV3Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9,Peptidase_S9_N
WZS1_k127_5052588_1	379066.GAU_3083	0.0002803	51.0	2EXVN@1|root,33R4S@2|Bacteria,1ZTD4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5064025_3	861299.J421_1538	2.769e-89	321.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
WZS1_k127_5064025_7	379066.GAU_2654	3.632e-32	136.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TPR_6
WZS1_k127_5064025_8	330214.NIDE3360	6.484e-15	88.0	COG0823@1|root,COG0823@2|Bacteria,3J0U9@40117|Nitrospirae	40117|Nitrospirae	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WZS1_k127_5064025_0	1408473.JHXO01000013_gene620	1.013e-235	742.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia	976|Bacteroidetes	E	Glutamate formimidoyltransferase	ftcD	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
WZS1_k127_5064025_4	1125725.HMPREF1325_1974	8.8e-78	280.0	COG1757@1|root,COG1757@2|Bacteria,2J72N@203691|Spirochaetes	203691|Spirochaetes	C	Na+/H+ antiporter family	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
WZS1_k127_5064025_6	614083.AWQR01000014_gene2415	8.693e-40	152.0	COG1142@1|root,COG1142@2|Bacteria,1RIJD@1224|Proteobacteria,2VXHA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5064025_2	1123240.ATVO01000004_gene950	4.464e-102	342.0	COG0667@1|root,COG0667@2|Bacteria,1MUKY@1224|Proteobacteria,2TRSI@28211|Alphaproteobacteria,2K988@204457|Sphingomonadales	204457|Sphingomonadales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS1_k127_5064025_9	1489678.RDMS_08830	6.88e-06	59.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	DUF4377,META,YscW
WZS1_k127_5064025_1	983917.RGE_36580	5.462e-138	447.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VIVJ@28216|Betaproteobacteria,1KMWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WZS1_k127_517587_7	497964.CfE428DRAFT_1132	3.246e-26	110.0	COG3303@1|root,COG3303@2|Bacteria,46UP1@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
WZS1_k127_517587_0	1499967.BAYZ01000159_gene546	3.075e-166	559.0	2EYYT@1|root,33S5J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_517587_6	861299.J421_3651	2.97e-33	138.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	yqjI	GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	PadR
WZS1_k127_517587_4	251229.Chro_5181	1.431e-60	223.0	COG0642@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1G09B@1117|Cyanobacteria,3VMB1@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
WZS1_k127_517587_2	1278073.MYSTI_01725	1.199e-109	362.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WM7T@28221|Deltaproteobacteria,2YUI5@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
WZS1_k127_517587_3	1254432.SCE1572_13235	4.817e-97	330.0	COG0842@1|root,COG0842@2|Bacteria,1Q99P@1224|Proteobacteria,42M53@68525|delta/epsilon subdivisions,2WMEY@28221|Deltaproteobacteria,2YU3D@29|Myxococcales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
WZS1_k127_517587_5	1267535.KB906767_gene927	6.896e-45	173.0	COG3595@1|root,COG3595@2|Bacteria,3Y5AF@57723|Acidobacteria,2JNIJ@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_517587_1	861299.J421_6111	4.356e-144	475.0	COG2091@1|root,COG2091@2|Bacteria,1ZUKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_519696_3	379066.GAU_1177	2.907e-43	164.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WZS1_k127_519696_1	861299.J421_2931	1.116e-67	251.0	28I3N@1|root,2Z87C@2|Bacteria,1ZT9U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
WZS1_k127_519696_5	1547437.LL06_09730	1.944e-14	79.0	2EI50@1|root,33BWC@2|Bacteria,1NK59@1224|Proteobacteria,2UT2Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_519696_2	506534.Rhein_2117	4.705e-58	205.0	COG4898@1|root,COG4898@2|Bacteria,1N0Z1@1224|Proteobacteria,1SQ7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_519696_0	1379270.AUXF01000007_gene968	1.592e-106	373.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000007_gene968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5202159_3	234267.Acid_6592	9.872e-37	152.0	COG0153@1|root,COG0153@2|Bacteria,3Y300@57723|Acidobacteria	2|Bacteria	G	Belongs to the GHMP kinase family. GalK subfamily	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WZS1_k127_5202159_5	1379270.AUXF01000001_gene2088	7.177e-08	59.0	2DDI2@1|root,2ZI6I@2|Bacteria,1ZVAF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5202159_1	861299.J421_0072	1.454e-113	378.0	COG0116@1|root,COG0116@2|Bacteria,1ZT80@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Putative RNA methylase family UPF0020	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	UPF0020
WZS1_k127_5202159_0	32042.PstZobell_02426	0.0	1201.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1Z2MN@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
WZS1_k127_5202159_2	379066.GAU_1315	1.929e-99	343.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cebB	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23,HlyD_D4,YtkA
WZS1_k127_5202159_4	379066.GAU_1316	4.871e-21	99.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	cebC	-	-	-	-	-	-	-	-	-	-	-	OEP
WZS1_k127_5219549_0	379066.GAU_0793	5.459e-64	228.0	COG0213@1|root,COG0213@2|Bacteria,1ZTBE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WZS1_k127_5219549_2	861299.J421_2718	2.587e-48	184.0	COG0457@1|root,COG0457@2|Bacteria,1ZTR4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5219549_4	641143.HMPREF9331_01522	7.211e-05	49.0	COG4980@1|root,COG4980@2|Bacteria,4NRSE@976|Bacteroidetes,1I46Y@117743|Flavobacteriia,1ES3U@1016|Capnocytophaga	976|Bacteroidetes	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
WZS1_k127_5219549_3	1297742.A176_02760	3.084e-20	102.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,4304I@68525|delta/epsilon subdivisions,2WVDN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	sensor histidine kinase response	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HATPase_c,HisKA,Response_reg
WZS1_k127_5219549_1	118166.JH976537_gene4010	2.696e-56	215.0	COG0272@1|root,COG0272@2|Bacteria,1G12K@1117|Cyanobacteria,1H874@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WZS1_k127_5268157_0	1379270.AUXF01000001_gene2588	2.201e-194	619.0	COG4188@1|root,COG4188@2|Bacteria,1ZUJV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
WZS1_k127_5268157_1	1379270.AUXF01000001_gene2583	2.056e-43	182.0	COG2067@1|root,COG2067@2|Bacteria,1ZUT4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5268157_2	525904.Tter_2307	1.922e-11	65.0	COG3004@1|root,COG3004@2|Bacteria,2NNWA@2323|unclassified Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
WZS1_k127_5276396_0	1089550.ATTH01000001_gene237	3.354e-166	546.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WZS1_k127_5276396_1	861299.J421_3849	3.174e-23	107.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WZS1_k127_5290958_2	861299.J421_3004	7.024e-80	282.0	COG0334@1|root,COG0334@2|Bacteria,1ZTBQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS1_k127_5290958_1	861299.J421_3002	2.001e-128	416.0	COG1250@1|root,COG1250@2|Bacteria,1ZSRN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WZS1_k127_5290958_3	1122237.AUGQ01000012_gene511	2.15e-18	99.0	COG1266@1|root,COG1266@2|Bacteria,2GMJ1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WZS1_k127_5290958_0	485913.Krac_12015	1.798e-139	454.0	COG0183@1|root,COG0183@2|Bacteria,2G66E@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS1_k127_5290958_4	204773.HEAR1801	1.028e-13	74.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,472DF@75682|Oxalobacteraceae	28216|Betaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WZS1_k127_5294697_3	861299.J421_3578	1.864e-58	205.0	COG0100@1|root,COG0100@2|Bacteria,1ZTMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WZS1_k127_5294697_2	861299.J421_3577	5.446e-85	286.0	COG0522@1|root,COG0522@2|Bacteria,1ZTGJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WZS1_k127_5294697_0	1379270.AUXF01000003_gene3883	4.337e-137	445.0	COG0202@1|root,COG0202@2|Bacteria,1ZTEV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WZS1_k127_5294697_4	861299.J421_3575	1.392e-39	154.0	COG0203@1|root,COG0203@2|Bacteria,1ZTPM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WZS1_k127_5294697_5	401053.AciPR4_0433	1.35e-21	95.0	COG0227@1|root,COG0227@2|Bacteria,3Y5KC@57723|Acidobacteria,2JJYY@204432|Acidobacteriia	204432|Acidobacteriia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WZS1_k127_5294697_1	1379270.AUXF01000003_gene3886	2.651e-129	417.0	COG1089@1|root,COG1089@2|Bacteria,1ZSR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
WZS1_k127_5325483_0	1068978.AMETH_0143	1.069e-121	412.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DZ2U@85010|Pseudonocardiales	201174|Actinobacteria	I	AMP-forming long-chain acyl-CoA synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
WZS1_k127_5325483_1	882083.SacmaDRAFT_5687	6.258e-104	357.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4E1TV@85010|Pseudonocardiales	201174|Actinobacteria	E	pfam abc	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS1_k127_5325483_2	882083.SacmaDRAFT_5686	4.555e-96	335.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DY02@85010|Pseudonocardiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WZS1_k127_5325483_3	1279017.AQYJ01000028_gene2525	2.369e-90	325.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,46479@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS1_k127_5337566_1	1384054.N790_04340	1.393e-146	475.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1X362@135614|Xanthomonadales	135614|Xanthomonadales	G	Dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
WZS1_k127_5337566_0	379066.GAU_2322	1.359e-235	744.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1ZSS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
WZS1_k127_5358200_1	1035308.AQYY01000002_gene312	4.412e-16	79.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,263TH@186807|Peptococcaceae	186801|Clostridia	M	PFAM NAD-dependent epimerase dehydratase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WZS1_k127_5358200_0	1265503.KB905162_gene3593	1.584e-69	263.0	COG2091@1|root,COG2091@2|Bacteria,1MY8E@1224|Proteobacteria,1RQAI@1236|Gammaproteobacteria,2Q7GY@267889|Colwelliaceae	1236|Gammaproteobacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WZS1_k127_5363471_5	861299.J421_2566	1.09e-29	123.0	COG0223@1|root,COG0223@2|Bacteria,1ZTE5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WZS1_k127_5363471_7	404589.Anae109_1348	2.538e-16	90.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,2YVSW@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
WZS1_k127_5363471_8	1131812.JQMS01000001_gene263	2.372e-14	81.0	2DNS7@1|root,32YWC@2|Bacteria,4NSJ6@976|Bacteroidetes,1I4FI@117743|Flavobacteriia,2NXP6@237|Flavobacterium	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WZS1_k127_5363471_1	861299.J421_2565	1.877e-78	277.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1ZTGM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
WZS1_k127_5363471_9	292459.STH1353	6.58e-14	81.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WZS1_k127_5363471_2	379066.GAU_0621	5.788e-74	264.0	COG0036@1|root,COG0036@2|Bacteria,1ZSP8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WZS1_k127_5363471_4	379066.GAU_0620	3.568e-38	158.0	COG0526@1|root,COG0526@2|Bacteria,1ZTMM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WZS1_k127_5363471_0	1379270.AUXF01000004_gene3265	3.514e-111	370.0	COG0533@1|root,COG0533@2|Bacteria,1ZT0P@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WZS1_k127_5363471_3	379066.GAU_0618	1.275e-58	221.0	COG0682@1|root,COG0682@2|Bacteria,1ZSYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WZS1_k127_5363471_6	340.xcc-b100_0546	6.751e-20	97.0	2DNS7@1|root,32YWC@2|Bacteria,1QU0X@1224|Proteobacteria,1SCKY@1236|Gammaproteobacteria,1X875@135614|Xanthomonadales	135614|Xanthomonadales	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WZS1_k127_5363471_10	1304880.JAGB01000002_gene2193	2.662e-13	72.0	COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,24RC0@186801|Clostridia	186801|Clostridia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS01470	ACPS
WZS1_k127_5370658_2	84531.JMTZ01000031_gene109	4.926e-81	277.0	COG4912@1|root,COG4912@2|Bacteria,1RGVM@1224|Proteobacteria,1T116@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WZS1_k127_5370658_3	35754.JNYJ01000008_gene3336	5.791e-47	176.0	COG0346@1|root,COG3832@1|root,COG0346@2|Bacteria,COG3832@2|Bacteria,2IKTR@201174|Actinobacteria,4DDP0@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WZS1_k127_5370658_1	861299.J421_5794	1.322e-125	434.0	COG0515@1|root,COG0515@2|Bacteria,1ZUMJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
WZS1_k127_5370658_4	1379270.AUXF01000002_gene1293	5.418e-46	169.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WZS1_k127_5370658_5	1125863.JAFN01000001_gene2333	1.258e-28	117.0	COG2161@1|root,COG2161@2|Bacteria,1R2Q0@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WZS1_k127_5370658_0	643867.Ftrac_0365	0.0	1072.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47U4M@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WZS1_k127_5385473_1	1292034.OR37_00751	3.789e-106	369.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TQRF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	3.4.13.22,3.4.16.4	ko:K01286,ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Beta-lactamase
WZS1_k127_5385473_3	1254432.SCE1572_50865	2.933e-56	211.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2YUC9@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS1_k127_5385473_0	497965.Cyan7822_5217	1.818e-164	554.0	COG2936@1|root,COG2936@2|Bacteria,1G1U8@1117|Cyanobacteria,3KHKK@43988|Cyanothece	1117|Cyanobacteria	S	X-Pro dipeptidyl-peptidase domain protein	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_5385473_2	204669.Acid345_0678	9.591e-63	246.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	yagE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WZS1_k127_5385926_0	1123278.KB893415_gene3495	5.111e-196	618.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NFTM@976|Bacteroidetes,47NS1@768503|Cytophagia	976|Bacteroidetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
WZS1_k127_5385926_5	1125863.JAFN01000001_gene1026	1.103e-81	282.0	COG1101@1|root,COG1101@2|Bacteria,1MVDM@1224|Proteobacteria,42N3W@68525|delta/epsilon subdivisions,2WJD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter related	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
WZS1_k127_5385926_6	794903.OPIT5_07150	1.156e-71	252.0	COG4120@1|root,COG4120@2|Bacteria,46YK2@74201|Verrucomicrobia,3K9RK@414999|Opitutae	414999|Opitutae	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
WZS1_k127_5385926_9	584708.Apau_0054	4.629e-31	141.0	COG2984@1|root,COG2984@2|Bacteria,3TBSS@508458|Synergistetes	508458|Synergistetes	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
WZS1_k127_5385926_3	1265310.CCBD010000065_gene939	2.234e-151	501.0	COG0515@1|root,COG2199@1|root,COG0515@2|Bacteria,COG3706@2|Bacteria,2H5ZS@201174|Actinobacteria,232IX@1762|Mycobacteriaceae	2|Bacteria	KLT	PFAM Protein kinase	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheX,HATPase_c,HisKA,Response_reg
WZS1_k127_5385926_7	1038860.AXAP01000101_gene5279	1.586e-51	184.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U76I@28211|Alphaproteobacteria,3JYR4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WZS1_k127_5385926_1	1173027.Mic7113_4161	1.285e-179	599.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
WZS1_k127_5385926_8	357808.RoseRS_1949	2.99e-42	179.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G8CK@200795|Chloroflexi,3776C@32061|Chloroflexia	32061|Chloroflexia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
WZS1_k127_5385926_2	1173027.Mic7113_4161	1.187e-170	579.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
WZS1_k127_5385926_4	1173027.Mic7113_4161	1.975e-109	363.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
WZS1_k127_5398111_2	861299.J421_3134	4.743e-44	168.0	COG4206@1|root,COG4206@2|Bacteria	2|Bacteria	H	cobalamin-transporting ATPase activity	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
WZS1_k127_5398111_1	929703.KE386491_gene2187	4.73e-75	261.0	COG3752@1|root,COG3752@2|Bacteria,4NJXA@976|Bacteroidetes,47PJY@768503|Cytophagia	976|Bacteroidetes	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WZS1_k127_5398111_3	1112274.KI911560_gene2253	7.541e-30	125.0	2E3Q3@1|root,32YN2@2|Bacteria,1NB4I@1224|Proteobacteria,2WIG3@28216|Betaproteobacteria,2KNYV@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5398111_0	886293.Sinac_1862	6.678e-222	713.0	COG2234@1|root,COG2234@2|Bacteria,2IWTP@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WZS1_k127_5438045_1	861299.J421_0464	1.978e-16	81.0	COG0793@1|root,COG0793@2|Bacteria,1ZT92@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WZS1_k127_5438045_0	1121957.ATVL01000007_gene1796	5.562e-72	267.0	COG3975@1|root,COG3975@2|Bacteria,4NGTY@976|Bacteroidetes,47KE2@768503|Cytophagia	976|Bacteroidetes	S	protease with the C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
WZS1_k127_5438045_2	469383.Cwoe_0906	1.603e-06	57.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WZS1_k127_5459524_3	1198114.AciX9_2997	8.084e-45	169.0	COG1171@1|root,COG1171@2|Bacteria,3Y2UN@57723|Acidobacteria,2JI1Z@204432|Acidobacteriia	204432|Acidobacteriia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS1_k127_5459524_0	861299.J421_2396	0.0	1176.0	COG0188@1|root,COG0188@2|Bacteria,1ZTFF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WZS1_k127_5459524_6	1317122.ATO12_23285	1.14e-07	60.0	2EFT5@1|root,339J5@2|Bacteria,4NZGJ@976|Bacteroidetes,1I6IW@117743|Flavobacteriia,2YJPE@290174|Aquimarina	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5459524_1	1379270.AUXF01000002_gene1596	1.033e-120	401.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
WZS1_k127_5459524_4	944480.ATUV01000001_gene624	9.298e-15	86.0	COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,439II@68525|delta/epsilon subdivisions,2X4UY@28221|Deltaproteobacteria,2M6VH@213113|Desulfurellales	28221|Deltaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5459524_2	1379270.AUXF01000004_gene3210	3.623e-103	346.0	COG0841@1|root,COG0841@2|Bacteria,1ZUFU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WZS1_k127_546457_5	861299.J421_0306	7.514e-20	92.0	COG1413@1|root,COG1413@2|Bacteria,1ZTQY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WZS1_k127_546457_3	861299.J421_0305	3.219e-62	226.0	COG1413@1|root,COG1413@2|Bacteria,1ZTU2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WZS1_k127_546457_4	379066.GAU_1078	2.845e-55	202.0	2CISN@1|root,2Z7MB@2|Bacteria,1ZU2Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Gluconate 2-dehydrogenase subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	Gluconate_2-dh3
WZS1_k127_546457_0	379066.GAU_1077	6.543e-241	775.0	COG2303@1|root,COG2303@2|Bacteria,1ZTG8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WZS1_k127_546457_1	293826.Amet_4112	4.427e-136	441.0	COG0031@1|root,COG0031@2|Bacteria,1UZEQ@1239|Firmicutes,24BCR@186801|Clostridia,36G6F@31979|Clostridiaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS1_k127_546457_2	861299.J421_4089	7.055e-122	403.0	COG1680@1|root,COG1680@2|Bacteria,1ZUDD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_5467935_8	443906.CMM_0263	7.225e-37	143.0	COG1181@1|root,COG1181@2|Bacteria,2GRWM@201174|Actinobacteria,4FRR6@85023|Microbacteriaceae	201174|Actinobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WZS1_k127_5467935_1	861299.J421_0897	4.219e-180	581.0	COG0031@1|root,COG0031@2|Bacteria,1ZTA6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EK	Domain in cystathionine beta-synthase and other proteins.	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
WZS1_k127_5467935_9	1385515.N791_05645	8.375e-09	62.0	COG0810@1|root,COG0810@2|Bacteria,1NHEC@1224|Proteobacteria,1T6H8@1236|Gammaproteobacteria,1X7HB@135614|Xanthomonadales	135614|Xanthomonadales	M	COG0810 Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
WZS1_k127_5467935_7	379066.GAU_0368	1.29e-44	186.0	28NN4@1|root,2ZBNJ@2|Bacteria,1ZTTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5467935_3	1379270.AUXF01000002_gene1584	1.498e-137	467.0	COG2132@1|root,COG2132@2|Bacteria,1ZUD9@142182|Gemmatimonadetes	2|Bacteria	Q	Multicopper oxidase	-	-	1.16.3.3	ko:K22348	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WZS1_k127_5467935_0	1125863.JAFN01000001_gene2068	8.152e-234	750.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WZS1_k127_5467935_10	1123073.KB899241_gene1816	0.000474	52.0	COG3147@1|root,COG3147@2|Bacteria,1N7VS@1224|Proteobacteria,1SZWM@1236|Gammaproteobacteria,1XCXX@135614|Xanthomonadales	135614|Xanthomonadales	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
WZS1_k127_5467935_6	1379270.AUXF01000002_gene1166	1.303e-52	199.0	COG1466@1|root,COG1466@2|Bacteria,1ZSSZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WZS1_k127_5467935_5	379066.GAU_3916	9.12e-56	201.0	COG0494@1|root,COG0494@2|Bacteria,1ZTQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WZS1_k127_5467935_4	751944.HALDL1_11185	4.466e-83	285.0	COG1028@1|root,arCOG01259@2157|Archaea,2XV13@28890|Euryarchaeota,23URP@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WZS1_k127_5467935_2	335543.Sfum_0297	1.888e-154	504.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,43C6Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	nonribosomal peptide	matB	-	6.2.1.3	ko:K00666,ko:K01897,ko:K18660,ko:K18661	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
WZS1_k127_5503419_0	861299.J421_5944	6.467e-238	745.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_5503419_1	861299.J421_0542	1.899e-76	261.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
WZS1_k127_5503419_2	1385517.N800_11085	6.761e-28	125.0	2BSVT@1|root,32MZC@2|Bacteria,1QCV9@1224|Proteobacteria,1T8NQ@1236|Gammaproteobacteria,1XAZU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5503419_3	1286093.C266_15487	2.377e-07	54.0	COG2303@1|root,COG2303@2|Bacteria,1MU3F@1224|Proteobacteria,2VIBA@28216|Betaproteobacteria,1KFJJ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM glucose-methanol-choline oxidoreductase	-	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
WZS1_k127_5511588_2	1379270.AUXF01000002_gene1364	8.943e-131	434.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1364|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5511588_0	861299.J421_1935	1.516e-249	790.0	COG2091@1|root,COG2091@2|Bacteria,1ZU9H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5511588_1	861299.J421_5972	4.829e-135	441.0	2BS4J@1|root,32M5G@2|Bacteria,1ZUJX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5511588_3	1150864.MILUP08_43122	3.604e-87	295.0	COG2755@1|root,COG2755@2|Bacteria,2GJUC@201174|Actinobacteria,4DI90@85008|Micromonosporales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WZS1_k127_552642_1	886379.AEWI01000014_gene1414	7.396e-44	163.0	COG1215@1|root,COG1215@2|Bacteria,4NFUA@976|Bacteroidetes,2FPUN@200643|Bacteroidia,3XKCY@558415|Marinilabiliaceae	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
WZS1_k127_552642_0	203119.Cthe_1326	3.164e-243	765.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WGRU@541000|Ruminococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WZS1_k127_552642_2	326427.Cagg_3740	1.027e-22	106.0	COG0697@1|root,COG0697@2|Bacteria,2G7RS@200795|Chloroflexi,377VC@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS1_k127_5559334_0	574087.Acear_2132	5.112e-237	747.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,3WBKH@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
WZS1_k127_5559334_1	886293.Sinac_2688	1.136e-222	709.0	COG3379@1|root,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	2|Bacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WZS1_k127_5559334_2	886293.Sinac_1691	1.573e-74	255.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WZS1_k127_5591222_1	558884.JRGM01000049_gene2767	4.603e-92	313.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,1RQES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	salL	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
WZS1_k127_5591222_0	378806.STAUR_1879	1.367e-119	412.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria,2YTX2@29|Myxococcales	28221|Deltaproteobacteria	P	TrkA-C domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
WZS1_k127_5593265_1	452637.Oter_1671	4.656e-117	406.0	COG0591@1|root,COG0591@2|Bacteria,46S93@74201|Verrucomicrobia,3K7R7@414999|Opitutae	414999|Opitutae	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WZS1_k127_5593265_0	1379270.AUXF01000003_gene3768	6.295e-199	646.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
WZS1_k127_5596710_1	330214.NIDE2247	2.605e-215	700.0	COG0587@1|root,COG0587@2|Bacteria,3J0FE@40117|Nitrospirae	2|Bacteria	L	DNA-directed DNA polymerase	dnaE-2	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
WZS1_k127_5596710_2	1532557.JL37_22315	3.647e-103	366.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	-	-	-	ko:K05802	-	-	-	-	ko00000,ko02000	1.A.23.1.1	-	-	MS_channel
WZS1_k127_5596710_0	861299.J421_2171	0.0	1380.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1ZSS1@142182|Gemmatimonadetes	2|Bacteria	O	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
WZS1_k127_5609555_0	649638.Trad_0840	0.0	1069.0	COG1012@1|root,COG1012@2|Bacteria,1WIGH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WZS1_k127_5609555_5	1384054.N790_06800	6.215e-59	232.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,1RSIB@1236|Gammaproteobacteria,1X6UM@135614|Xanthomonadales	135614|Xanthomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS1_k127_5609555_1	861299.J421_3843	1.059e-126	423.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,1ZTH0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	FPT	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
WZS1_k127_5609555_6	247490.KSU1_B0729	1.362e-51	194.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WZS1_k127_5609555_3	1121472.AQWN01000005_gene2417	7.407e-99	342.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,260A5@186807|Peptococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WZS1_k127_5609555_2	867903.ThesuDRAFT_01222	8.221e-102	337.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3WCRK@538999|Clostridiales incertae sedis	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WZS1_k127_5609555_4	443144.GM21_2504	8.631e-87	301.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WMUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS1_k127_5609555_7	204669.Acid345_2974	1.002e-37	144.0	COG0573@1|root,COG0573@2|Bacteria,3Y42Y@57723|Acidobacteria,2JIJN@204432|Acidobacteriia	204432|Acidobacteriia	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS1_k127_5634745_4	573370.DMR_03420	8.633e-24	101.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,42S33@68525|delta/epsilon subdivisions,2WNKG@28221|Deltaproteobacteria,2MC3F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5634745_0	880073.Calab_3557	7.851e-115	383.0	COG1215@1|root,COG1215@2|Bacteria,2NQN3@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4,Glycos_transf_2
WZS1_k127_5634745_3	861299.J421_3205	9.761e-73	262.0	COG1159@1|root,COG1159@2|Bacteria,1ZUSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WZS1_k127_5634745_5	1125863.JAFN01000001_gene531	2.773e-18	85.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
WZS1_k127_5634745_2	243233.MCA0142	9.108e-85	303.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,1S1GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
WZS1_k127_5634745_1	1379270.AUXF01000006_gene312	1.276e-94	320.0	COG2199@1|root,COG2199@2|Bacteria,1ZT1F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WZS1_k127_5634745_6	861299.J421_3210	1.043e-12	72.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
WZS1_k127_5683627_1	1379270.AUXF01000004_gene3254	1.431e-74	253.0	COG2255@1|root,COG2255@2|Bacteria,1ZT9W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WZS1_k127_5683627_3	861299.J421_2579	1.111e-46	180.0	COG0632@1|root,COG0632@2|Bacteria,1ZTR0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WZS1_k127_5683627_2	1379270.AUXF01000004_gene3248	3.607e-53	193.0	COG0817@1|root,COG0817@2|Bacteria,1ZTKI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WZS1_k127_5683627_0	861299.J421_2581	5.427e-80	272.0	COG0217@1|root,COG0217@2|Bacteria,1ZTF4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WZS1_k127_572165_6	1379270.AUXF01000006_gene311	2.263e-27	114.0	2F3JX@1|root,33WDB@2|Bacteria,1ZTZI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
WZS1_k127_572165_3	861299.J421_3211	1.201e-130	426.0	COG1186@1|root,COG1186@2|Bacteria,1ZTE4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WZS1_k127_572165_1	1121468.AUBR01000035_gene1398	2.124e-149	497.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
WZS1_k127_572165_4	379066.GAU_1580	1.107e-111	374.0	COG4591@1|root,COG4591@2|Bacteria,1ZT1N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WZS1_k127_572165_5	861299.J421_3214	4.495e-76	263.0	COG1136@1|root,COG1136@2|Bacteria,1ZSNF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WZS1_k127_572165_2	1379270.AUXF01000006_gene305	2.69e-132	433.0	COG3869@1|root,COG3869@2|Bacteria,1ZT9I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	ATP:guanido phosphotransferase, C-terminal catalytic domain	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
WZS1_k127_572165_0	521674.Plim_0603	1.98e-207	661.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WZS1_k127_5724176_2	411462.DORLON_02383	4.806e-44	169.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,27UYT@189330|Dorea	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WZS1_k127_5724176_1	192875.XP_004348030.1	3.848e-74	254.0	COG0131@1|root,KOG3143@2759|Eukaryota,38GFB@33154|Opisthokonta	33154|Opisthokonta	E	Belongs to the imidazoleglycerol-phosphate dehydratase family	HIS3	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
WZS1_k127_5724176_3	593907.Celgi_3092	2.569e-37	154.0	COG0079@1|root,COG0079@2|Bacteria,2GJXS@201174|Actinobacteria,4F0HY@85016|Cellulomonadaceae	201174|Actinobacteria	E	May catalyze the transamination reaction in phenylalanine biosynthesis	pat	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS1_k127_5724176_0	1089551.KE386572_gene3673	5.456e-102	340.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2TT0H@28211|Alphaproteobacteria,4BR33@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
WZS1_k127_5741901_2	234267.Acid_4497	1.085e-46	187.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y44T@57723|Acidobacteria	57723|Acidobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,Trans_reg_C
WZS1_k127_5741901_0	706587.Desti_4338	2.455e-175	557.0	COG2502@1|root,COG2502@2|Bacteria,1MVWF@1224|Proteobacteria	1224|Proteobacteria	E	aspartate--ammonia ligase	asnA	GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_2719,iECOK1_1307.ECOK1_4193,iECS88_1305.ECS88_4166,iUMN146_1321.UM146_18910,iUTI89_1310.UTI89_C4299	AsnA,tRNA-synt_2
WZS1_k127_5741901_1	795666.MW7_0950	2.488e-75	256.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria,1K1RE@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WZS1_k127_5741901_3	1123508.JH636443_gene5018	2.163e-40	162.0	COG3324@1|root,COG3324@2|Bacteria,2J3W8@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
WZS1_k127_5741901_4	1565129.JSFF01000021_gene674	3.149e-12	67.0	COG0500@1|root,COG2226@2|Bacteria,1PF9T@1224|Proteobacteria,1T9PG@1236|Gammaproteobacteria,2QDI5@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WZS1_k127_5750686_0	1379270.AUXF01000001_gene2742	0.0	1155.0	COG2866@1|root,COG2866@2|Bacteria,1ZSMP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
WZS1_k127_5750686_1	395961.Cyan7425_1166	3.865e-48	179.0	COG0164@1|root,COG0164@2|Bacteria,1G507@1117|Cyanobacteria,3KHNX@43988|Cyanothece	1117|Cyanobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WZS1_k127_5750686_2	562970.Btus_1455	3.045e-41	154.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,278F5@186823|Alicyclobacillaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WZS1_k127_5813073_10	1121091.AUMP01000008_gene3621	0.0002559	46.0	COG1834@1|root,COG1834@2|Bacteria,1W71J@1239|Firmicutes,4HF31@91061|Bacilli	91061|Bacilli	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
WZS1_k127_5813073_9	379066.GAU_0150	7.44e-08	61.0	2FK3G@1|root,34BRK@2|Bacteria,1ZU1V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
WZS1_k127_5813073_3	383372.Rcas_0019	7.145e-99	343.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,376ZQ@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_5813073_7	861299.J421_2300	2.422e-17	91.0	2ES15@1|root,33JK7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
WZS1_k127_5813073_2	1123023.JIAI01000001_gene6965	8.975e-101	357.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria,4E05J@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase, CocE NonD family	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_5813073_8	880072.Desac_1733	2.041e-14	78.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria	1224|Proteobacteria	M	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WZS1_k127_5813073_0	1384054.N790_05510	1.353e-225	727.0	COG0823@1|root,COG0823@2|Bacteria,1MWYK@1224|Proteobacteria,1RXYW@1236|Gammaproteobacteria,1XD03@135614|Xanthomonadales	135614|Xanthomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
WZS1_k127_5813073_4	886293.Sinac_0214	2.19e-85	307.0	COG3119@1|root,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
WZS1_k127_5813073_1	574087.Acear_2132	2.716e-215	692.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,3WBKH@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
WZS1_k127_5813073_5	861299.J421_6047	5.38e-60	233.0	COG0529@1|root,COG0529@2|Bacteria	2|Bacteria	P	adenylylsulfate kinase activity	cysC	GO:0003674,GO:0003824,GO:0004020,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,DUF2061
WZS1_k127_5813073_6	861299.J421_6048	3.006e-58	206.0	COG0175@1|root,COG0175@2|Bacteria,1ZV0E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EH	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
WZS1_k127_5828489_3	1297742.A176_00725	1.561e-19	93.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42QW3@68525|delta/epsilon subdivisions,2WNT9@28221|Deltaproteobacteria,2YYCZ@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS1_k127_5828489_0	1123072.AUDH01000001_gene2904	4.242e-149	480.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	204441|Rhodospirillales	C	III protein, CoA-transferase family	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WZS1_k127_5828489_2	1379270.AUXF01000003_gene3795	1.453e-46	172.0	COG0661@1|root,COG0661@2|Bacteria,1ZSYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
WZS1_k127_5828489_1	861299.J421_1451	9.349e-78	278.0	COG0661@1|root,COG0661@2|Bacteria,1ZSYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
WZS1_k127_5828489_4	56780.SYN_01961	1.664e-16	87.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25,LysM,PG_binding_1,Peptidase_C14
WZS1_k127_5828489_5	240015.ACP_2201	1.038e-09	60.0	COG2855@1|root,COG2855@2|Bacteria,3Y3R4@57723|Acidobacteria,2JHTG@204432|Acidobacteriia	204432|Acidobacteriia	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
WZS1_k127_5845356_9	279010.BL04008	0.0004252	49.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,4HAY8@91061|Bacilli,1ZBNJ@1386|Bacillus	91061|Bacilli	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
WZS1_k127_5845356_6	926566.Terro_2636	1.229e-15	81.0	COG0720@1|root,COG0720@2|Bacteria,3Y4K2@57723|Acidobacteria,2JJD0@204432|Acidobacteriia	204432|Acidobacteriia	H	PFAM 6-pyruvoyl tetrahydropterin	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WZS1_k127_5845356_4	861299.J421_3923	1.754e-17	94.0	2F8UF@1|root,3416F@2|Bacteria,1ZTX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5845356_1	861299.J421_3922	1.095e-196	625.0	COG0696@1|root,COG0696@2|Bacteria,1ZSWH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
WZS1_k127_5845356_7	379066.GAU_2453	5.928e-11	70.0	2F9BP@1|root,341NP@2|Bacteria,1ZTX1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5845356_0	1379270.AUXF01000003_gene3474	1.913e-236	739.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1ZTG9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WZS1_k127_5845356_3	861299.J421_3916	2.978e-87	302.0	COG0618@1|root,COG0618@2|Bacteria,1ZSS0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	DHH family	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WZS1_k127_5845356_8	1123073.KB899244_gene266	2.626e-10	72.0	COG0316@1|root,COG0694@1|root,COG0316@2|Bacteria,COG0694@2|Bacteria,1MU8Y@1224|Proteobacteria,1RN7J@1236|Gammaproteobacteria,1X4F3@135614|Xanthomonadales	135614|Xanthomonadales	C	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins	nfuA	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn,NifU
WZS1_k127_5845356_2	861299.J421_3915	2.161e-121	399.0	COG0489@1|root,COG0489@2|Bacteria,1ZSW7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
WZS1_k127_5845356_5	1122134.KB893650_gene1488	1.782e-17	84.0	COG0733@1|root,COG0733@2|Bacteria,1MUZJ@1224|Proteobacteria,1RPCT@1236|Gammaproteobacteria,1XIJV@135619|Oceanospirillales	135619|Oceanospirillales	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
WZS1_k127_5848527_10	861299.J421_1805	9.871e-21	101.0	COG1416@1|root,COG1416@2|Bacteria,1ZU3V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5848527_1	309807.SRU_2034	3.204e-214	688.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
WZS1_k127_5848527_8	1125863.JAFN01000001_gene3582	6.52e-44	174.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,42MZQ@68525|delta/epsilon subdivisions,2WJNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WZS1_k127_5848527_6	1049564.TevJSym_aq00670	1.641e-68	248.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1J4WI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
WZS1_k127_5848527_7	1049564.TevJSym_aq00680	4.242e-67	236.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1JBVX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfE2	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
WZS1_k127_5848527_9	1049564.TevJSym_aq00690	8.255e-30	130.0	COG4659@1|root,COG4659@2|Bacteria,1REZV@1224|Proteobacteria,1T054@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
WZS1_k127_5848527_4	1049564.TevJSym_aq00700	7.064e-97	346.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
WZS1_k127_5848527_2	765910.MARPU_10730	9.776e-136	447.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WXET@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_8,RnfC_N,SLBB
WZS1_k127_5848527_12	2340.JV46_16940	1.705e-07	66.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	1.2.7.1	ko:K03737,ko:K05337	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
WZS1_k127_5848527_0	1379270.AUXF01000001_gene2161	0.0	1963.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
WZS1_k127_5848527_5	382464.ABSI01000002_gene4375	3.104e-88	303.0	COG2878@1|root,COG2878@2|Bacteria	2|Bacteria	C	electron transfer activity	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_7
WZS1_k127_5848527_3	1049564.TevJSym_bb00040	5.587e-97	327.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WZS1_k127_5848527_11	1049564.TevJSym_bb00050	1.832e-08	56.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WZS1_k127_5856409_4	1068980.ARVW01000001_gene2364	1.167e-53	196.0	COG0596@1|root,COG0596@2|Bacteria,2I320@201174|Actinobacteria,4EFEM@85010|Pseudonocardiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WZS1_k127_5856409_3	1089550.ATTH01000001_gene1757	8.936e-62	222.0	COG0463@1|root,COG0463@2|Bacteria,4NX3Y@976|Bacteroidetes,1FJXM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_24
WZS1_k127_5856409_7	1255043.TVNIR_2329	1.255e-09	62.0	COG4691@1|root,COG4691@2|Bacteria,1N09T@1224|Proteobacteria,1SH18@1236|Gammaproteobacteria,1WZQM@135613|Chromatiales	135613|Chromatiales	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
WZS1_k127_5856409_6	292564.Cyagr_1982	1.06e-29	127.0	COG4113@1|root,COG4113@2|Bacteria,1GEC8@1117|Cyanobacteria,22TX1@167375|Cyanobium	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WZS1_k127_5856409_1	1191523.MROS_1572	6.891e-133	430.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,Fer4_7
WZS1_k127_5856409_0	1191523.MROS_1571	1.063e-178	567.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hybB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	iAPECO1_1312.APECO1_3427,iE2348C_1286.E2348C_3282,iECABU_c1320.ECABU_c34010,iECOK1_1307.ECOK1_3414,iECS88_1305.ECS88_3377,iUMN146_1321.UM146_01380,iUTI89_1310.UTI89_C3417	NrfD
WZS1_k127_5856409_2	1191523.MROS_1570	4.153e-75	266.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2
WZS1_k127_5856409_5	1191523.MROS_1569	6.037e-50	186.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS1_k127_590180_2	572477.Alvin_1507	9.719e-54	194.0	COG0520@1|root,COG2166@1|root,COG0520@2|Bacteria,COG2166@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1WWTN@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SufE
WZS1_k127_590180_1	861299.J421_2088	1.053e-104	366.0	COG0719@1|root,COG0719@2|Bacteria,1ZSTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
WZS1_k127_590180_0	379066.GAU_3028	3.34e-124	402.0	COG0396@1|root,COG0396@2|Bacteria,1ZSRX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	ABC transporter	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WZS1_k127_5904731_3	509190.Cseg_0713	3.189e-31	127.0	COG1680@1|root,COG1680@2|Bacteria,1R49D@1224|Proteobacteria,2U4UG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_5904731_1	1205680.CAKO01000002_gene2583	2.398e-69	253.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,2JX7Q@204441|Rhodospirillales	204441|Rhodospirillales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WZS1_k127_5904731_0	926550.CLDAP_10980	4.864e-234	731.0	COG3033@1|root,COG3033@2|Bacteria,2G7YV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tpl	-	4.1.99.1,4.1.99.2	ko:K01667,ko:K01668	ko00350,ko00380,map00350,map00380	-	R00673,R00728	RC00209,RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WZS1_k127_5904731_2	1385935.N836_28980	1.472e-48	183.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WZS1_k127_5904731_4	483219.LILAB_18640	6.182e-30	128.0	COG1643@1|root,COG1643@2|Bacteria	2|Bacteria	L	helicase activity	-	-	3.6.4.13	ko:K03578,ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	AAA_11,AAA_12,DEAD,DUF3418,DUF4011,HA2,Helicase_C
WZS1_k127_5944466_0	861299.J421_2006	2.071e-111	396.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1ZUC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_5944466_1	379066.GAU_1955	2.522e-84	286.0	COG0317@1|root,COG0317@2|Bacteria,1ZT5M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WZS1_k127_5945855_1	634956.Geoth_2732	6.759e-52	196.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,1WEUB@129337|Geobacillus	91061|Bacilli	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iYO844.BSU15910	adh_short_C2
WZS1_k127_5945855_0	861299.J421_3938	5.071e-288	905.0	COG1966@1|root,COG1966@2|Bacteria,1ZSWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
WZS1_k127_5945855_3	1242864.D187_002889	1.811e-11	66.0	COG2879@1|root,COG2879@2|Bacteria,1N6TY@1224|Proteobacteria	1224|Proteobacteria	S	small protein	ybdD	-	-	-	-	-	-	-	-	-	-	-	Sel_put
WZS1_k127_5945855_2	1121380.JNIW01000009_gene1476	1.723e-38	152.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WZS1_k127_5948501_4	1121378.KB899739_gene3784	1.182e-25	110.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	slyA	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
WZS1_k127_5948501_0	861299.J421_1357	4.554e-191	605.0	COG2159@1|root,COG2159@2|Bacteria,1ZSR7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WZS1_k127_5948501_5	1496688.ER33_11570	6.088e-18	91.0	COG2336@1|root,COG2336@2|Bacteria,1G88T@1117|Cyanobacteria,22TUR@167375|Cyanobium	1117|Cyanobacteria	T	PFAM SpoVT AbrB like domain	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
WZS1_k127_5948501_1	880072.Desac_1069	1.365e-46	169.0	COG2337@1|root,COG2337@2|Bacteria,1N0JV@1224|Proteobacteria,42STH@68525|delta/epsilon subdivisions,2WP6X@28221|Deltaproteobacteria,2MSFP@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
WZS1_k127_5948501_7	983544.Lacal_2171	6.913e-09	64.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I70K@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
WZS1_k127_5948501_2	1379270.AUXF01000001_gene2080	1.94e-43	163.0	2E129@1|root,32WI1@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
WZS1_k127_5948501_6	379066.GAU_0126	6.138e-13	81.0	2EY2H@1|root,33RBE@2|Bacteria,1ZTHK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5948501_3	435908.IDSA_10480	6.096e-32	132.0	COG4222@1|root,COG4222@2|Bacteria,1R3RI@1224|Proteobacteria,1RQA4@1236|Gammaproteobacteria,2QFUB@267893|Idiomarinaceae	1236|Gammaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	XAC1238	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WZS1_k127_5955275_1	1379270.AUXF01000002_gene1557	5.969e-189	616.0	COG2091@1|root,COG2091@2|Bacteria,1ZUQA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5955275_0	518766.Rmar_1593	1.139e-300	934.0	COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes	976|Bacteroidetes	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
WZS1_k127_5955275_2	518766.Rmar_1595	2.516e-90	305.0	COG1228@1|root,COG1228@2|Bacteria,4NE6C@976|Bacteroidetes	976|Bacteroidetes	Q	Belongs to the metallo-dependent hydrolases superfamily. HutI family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WZS1_k127_597097_3	1379270.AUXF01000006_gene198	9.086e-10	66.0	297VI@1|root,2ZV24@2|Bacteria,1ZU61@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_597097_1	379066.GAU_1695	1.144e-36	145.0	COG1595@1|root,COG1595@2|Bacteria,1ZTKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS1_k127_597097_0	1122179.KB890458_gene744	4.721e-94	326.0	COG0612@1|root,COG0612@2|Bacteria,4NEDZ@976|Bacteroidetes,1IPY5@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS1_k127_597097_2	1121015.N789_05985	1.289e-17	89.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1X8AF@135614|Xanthomonadales	135614|Xanthomonadales	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS1_k127_597098_4	1227739.Hsw_0167	4.54e-11	72.0	COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,47XR4@768503|Cytophagia	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,OMP_b-brl_2
WZS1_k127_597098_2	861299.J421_1636	1.11e-38	152.0	2B1QU@1|root,31U6H@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
WZS1_k127_597098_3	379066.GAU_3650	4.675e-36	143.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	yisT	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
WZS1_k127_597098_1	1121405.dsmv_3343	4.447e-42	158.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42T22@68525|delta/epsilon subdivisions,2WPAE@28221|Deltaproteobacteria,2MKSI@213118|Desulfobacterales	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WZS1_k127_597098_0	1379270.AUXF01000002_gene1544	3.328e-45	176.0	COG3653@1|root,COG3653@2|Bacteria	2|Bacteria	Q	N-Acyl-D-aspartate D-glutamate deacylase	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_5982962_1	379066.GAU_1692	3.96e-12	74.0	COG0260@1|root,COG0260@2|Bacteria,1ZSPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WZS1_k127_5982962_0	861299.J421_1410	8.175e-131	428.0	COG0624@1|root,COG0624@2|Bacteria,1ZSYH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS1_k127_5988298_1	379066.GAU_1495	1.03e-10	72.0	COG0457@1|root,COG0457@2|Bacteria,1ZTCW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5988298_0	379066.GAU_2666	0.0	1199.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WZS1_k127_5995114_4	469383.Cwoe_0781	0.0002493	52.0	COG1164@1|root,COG1164@2|Bacteria,2HDPQ@201174|Actinobacteria,4CTTS@84995|Rubrobacteria	84995|Rubrobacteria	E	Oligoendopeptidase f	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
WZS1_k127_5995114_2	575540.Isop_2602	1.443e-266	845.0	COG1506@1|root,COG1506@2|Bacteria,2IYT8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WZS1_k127_5995114_0	251221.35211322	0.0	1093.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	AstE_AspA,Peptidase_M14
WZS1_k127_5995114_1	861299.J421_2219	1.34e-281	900.0	COG1629@1|root,COG4771@2|Bacteria,1ZT27@142182|Gemmatimonadetes	861299.J421_2219|-	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5999764_4	861299.J421_0460	2.565e-95	329.0	COG1807@1|root,COG1807@2|Bacteria,1ZUFB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WZS1_k127_5999764_3	1379270.AUXF01000002_gene1306	2.39e-170	543.0	COG1680@1|root,COG1680@2|Bacteria,1ZU44@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_5999764_0	1248916.ANFY01000007_gene2531	8.247e-220	704.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,2K16Q@204457|Sphingomonadales	204457|Sphingomonadales	EU	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_5999764_1	1121920.AUAU01000021_gene2510	5.779e-211	691.0	COG1013@1|root,COG1014@1|root,COG1013@2|Bacteria,COG1014@2|Bacteria,3Y3G3@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.7	ko:K00187	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	POR,TPP_enzyme_C
WZS1_k127_5999764_2	1121920.AUAU01000021_gene2509	2.078e-209	665.0	COG0674@1|root,COG0674@2|Bacteria,3Y3NB@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.7	ko:K00186	ko00280,ko01100,map00280,map01100	-	R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko01000	-	-	-	PFOR_II,POR_N
WZS1_k127_5999764_7	1131269.AQVV01000032_gene304	6.689e-05	49.0	2DCXT@1|root,2ZFR8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_5999764_5	1499967.BAYZ01000171_gene5549	3.174e-50	190.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WZS1_k127_5999764_6	264732.Moth_2112	6.108e-43	164.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WZS1_k127_6033611_1	379066.GAU_2342	1.634e-143	464.0	COG3653@1|root,COG3653@2|Bacteria,1ZUQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_6033611_2	1395571.TMS3_0108610	2.153e-128	426.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RR7T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS1_k127_6033611_5	1403819.BATR01000118_gene4062	8.926e-46	184.0	COG4276@1|root,COG4276@2|Bacteria,46W6H@74201|Verrucomicrobia,2IUR6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6033611_7	861299.J421_0091	1.617e-23	104.0	28XFN@1|root,2ZJD7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6033611_3	861299.J421_4290	7.472e-116	382.0	COG1171@1|root,COG1171@2|Bacteria,1ZTBP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS1_k127_6033611_6	1499967.BAYZ01000043_gene2285	1.206e-35	147.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WZS1_k127_6033611_0	861299.J421_6032	1.239e-213	675.0	COG3653@1|root,COG3653@2|Bacteria,1ZTAY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_6033611_4	1123393.KB891316_gene1481	4.533e-72	266.0	COG0500@1|root,COG2226@2|Bacteria,1RFPW@1224|Proteobacteria,2VRVY@28216|Betaproteobacteria,1KSWC@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS1_k127_6053628_2	861299.J421_2408	6.847e-87	292.0	COG0843@1|root,COG0843@2|Bacteria,1ZSMG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WZS1_k127_6053628_1	1382356.JQMP01000004_gene54	1.795e-96	329.0	COG1622@1|root,COG1622@2|Bacteria,2G6C0@200795|Chloroflexi,27XKX@189775|Thermomicrobia	189775|Thermomicrobia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
WZS1_k127_6053628_3	204669.Acid345_3224	1.943e-76	274.0	COG0006@1|root,COG0006@2|Bacteria,3Y36W@57723|Acidobacteria,2JI54@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WZS1_k127_6053628_4	379066.GAU_2860	1.516e-43	164.0	COG0782@1|root,COG0782@2|Bacteria,1ZTPD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Transcription elongation factor, N-terminal	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WZS1_k127_6053628_6	861299.J421_2069	1.968e-38	147.0	COG0234@1|root,COG0234@2|Bacteria,1ZU6V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	-	-	-	-	-	-	-	-	-	-	-	-	Cpn10
WZS1_k127_6053628_5	1278073.MYSTI_05047	2.805e-40	164.0	COG2267@1|root,COG2267@2|Bacteria,1RFE1@1224|Proteobacteria,42UMK@68525|delta/epsilon subdivisions,2WQNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WZS1_k127_6053628_0	861299.J421_2836	1.727e-97	328.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_2836|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WZS1_k127_6055323_5	1121920.AUAU01000005_gene1038	1.988e-37	146.0	COG1228@1|root,COG1228@2|Bacteria,3Y4IP@57723|Acidobacteria	57723|Acidobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_6055323_9	518766.Rmar_2421	5.678e-31	128.0	COG1569@1|root,COG1569@2|Bacteria	2|Bacteria	S	PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
WZS1_k127_6055323_11	671143.DAMO_1892	1.695e-22	98.0	COG3905@1|root,COG3905@2|Bacteria	2|Bacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
WZS1_k127_6055323_14	1380356.JNIK01000017_gene2890	6.434e-06	48.0	2AHWM@1|root,3189H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6055323_3	1198452.Jab_1c09570	1.588e-60	224.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,2WEEM@28216|Betaproteobacteria,477X8@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_6055323_4	926560.KE387027_gene303	7.012e-41	162.0	COG1917@1|root,COG1917@2|Bacteria,1WMIY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6055323_1	861299.J421_5836	1.007e-100	344.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_5836|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WZS1_k127_6055323_7	314266.SKA58_00750	1.908e-34	152.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales	204457|Sphingomonadales	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WZS1_k127_6055323_12	395019.Bmul_3792	2.004e-20	93.0	COG4118@1|root,COG4118@2|Bacteria,1NAEH@1224|Proteobacteria,2VWR1@28216|Betaproteobacteria,1KA36@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WZS1_k127_6055323_10	933262.AXAM01000024_gene727	4.316e-30	123.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,42WUI@68525|delta/epsilon subdivisions,2WT5M@28221|Deltaproteobacteria,2MNKV@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WZS1_k127_6055323_0	1379270.AUXF01000002_gene1600	3.402e-209	683.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000002_gene1600|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6055323_8	1232429.CBLL010000157_gene2347	2.704e-31	126.0	COG3549@1|root,COG3549@2|Bacteria,2IT6K@201174|Actinobacteria,1WC3M@1268|Micrococcaceae	201174|Actinobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
WZS1_k127_6055323_6	879212.DespoDRAFT_01012	1.148e-35	140.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42VQB@68525|delta/epsilon subdivisions,2WQFH@28221|Deltaproteobacteria,2MKMC@213118|Desulfobacterales	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WZS1_k127_6055323_2	420662.Mpe_A0759	1.262e-92	310.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VMB2@28216|Betaproteobacteria,1KMU4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_6128095_2	861299.J421_2924	6.351e-22	106.0	COG4932@1|root,COG4932@2|Bacteria,1ZUFE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	-
WZS1_k127_6128095_1	765869.BDW_01925	2.077e-47	175.0	COG0727@1|root,COG0727@2|Bacteria,1N3F5@1224|Proteobacteria,42T7I@68525|delta/epsilon subdivisions,2MU1A@213481|Bdellovibrionales,2WPNZ@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
WZS1_k127_6128095_0	1123508.JH636442_gene4006	0.0	1114.0	COG4447@1|root,COG4447@2|Bacteria,2J1J5@203682|Planctomycetes	203682|Planctomycetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
WZS1_k127_6178566_10	1379270.AUXF01000005_gene457	4.123e-30	131.0	COG1136@1|root,COG1136@2|Bacteria,1ZSKH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS1_k127_6178566_7	861299.J421_1983	1.291e-58	220.0	COG1538@1|root,COG1538@2|Bacteria,1ZT9S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
WZS1_k127_6178566_9	1379270.AUXF01000002_gene1849	6.948e-38	150.0	COG1595@1|root,COG1595@2|Bacteria,1ZT0A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS1_k127_6178566_1	314278.NB231_02168	6.927e-103	355.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,1RPQG@1236|Gammaproteobacteria,1WXED@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
WZS1_k127_6178566_6	861299.J421_2433	9.852e-70	244.0	COG2316@1|root,COG2316@2|Bacteria,1ZTH6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS1_k127_6178566_8	224719.Abm4_1672	3.761e-56	201.0	COG0652@1|root,arCOG04767@2157|Archaea,2XTHC@28890|Euryarchaeota,23P0H@183925|Methanobacteria	183925|Methanobacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
WZS1_k127_6178566_4	861299.J421_2443	6.197e-80	278.0	COG0177@1|root,COG0177@2|Bacteria,1ZT7K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WZS1_k127_6178566_0	1382306.JNIM01000001_gene3872	6.402e-129	433.0	COG1387@1|root,COG1387@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
WZS1_k127_6178566_5	379066.GAU_0538	9.613e-77	266.0	COG0596@1|root,COG0596@2|Bacteria,1ZTAV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_6
WZS1_k127_6178566_2	861299.J421_2446	2.337e-100	345.0	COG0123@1|root,COG0123@2|Bacteria,1ZT64@142182|Gemmatimonadetes	142182|Gemmatimonadetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WZS1_k127_6178566_13	661478.OP10G_3830	3.194e-25	110.0	COG1956@1|root,COG1956@2|Bacteria	2|Bacteria	T	GAF domain-containing protein	yebR	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2
WZS1_k127_6178566_3	861299.J421_2448	1.211e-95	331.0	COG0265@1|root,COG2234@1|root,COG0265@2|Bacteria,COG2234@2|Bacteria,1ZTZW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WZS1_k127_6178566_12	861299.J421_2449	1.581e-27	128.0	COG1413@1|root,COG1413@2|Bacteria,1ZTWT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
WZS1_k127_6178566_11	861299.J421_3746	2.178e-28	130.0	COG0760@1|root,COG0760@2|Bacteria,1ZT5S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3
WZS1_k127_6178566_16	1123073.KB899242_gene1378	8.761e-07	60.0	2DEWH@1|root,2ZPJ0@2|Bacteria,1P5UM@1224|Proteobacteria,1ST8K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6210647_3	1283300.ATXB01000001_gene1514	3.469e-09	67.0	COG0726@1|root,COG0726@2|Bacteria,1MWR2@1224|Proteobacteria,1RP7J@1236|Gammaproteobacteria,1XFSY@135618|Methylococcales	135618|Methylococcales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WZS1_k127_6210647_1	886293.Sinac_6462	1.908e-117	406.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WZS1_k127_6210647_0	489825.LYNGBM3L_64070	2.295e-128	429.0	COG0438@1|root,COG0438@2|Bacteria,1G1X1@1117|Cyanobacteria,1H8D4@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WZS1_k127_6210647_2	1198232.CYCME_1451	1.489e-17	87.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria,4612P@72273|Thiotrichales	72273|Thiotrichales	M	Glycosyl transferases group 1	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WZS1_k127_6218155_2	324602.Caur_3095	8.602e-49	183.0	COG0697@1|root,COG0697@2|Bacteria,2G7RS@200795|Chloroflexi,377VC@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS1_k127_6218155_0	203119.Cthe_1326	1.794e-244	769.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WGRU@541000|Ruminococcaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WZS1_k127_6218155_1	1453501.JELR01000002_gene622	2.511e-72	254.0	COG0463@1|root,COG0463@2|Bacteria,1QX0V@1224|Proteobacteria,1T32V@1236|Gammaproteobacteria,4647P@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
WZS1_k127_6224664_2	1122223.KB890700_gene2000	2.653e-132	437.0	COG1574@1|root,COG1574@2|Bacteria,1WINV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS1_k127_6224664_0	760192.Halhy_1592	1.497e-179	584.0	COG1012@1|root,COG1012@2|Bacteria,4NEB7@976|Bacteroidetes,1IQTP@117747|Sphingobacteriia	976|Bacteroidetes	C	Belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WZS1_k127_6224664_1	204669.Acid345_1633	2.436e-176	574.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.99.6	ko:K00316	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R01914,R01915	RC00053,RC00225	ko00000,ko00001,ko01000	-	-	-	DAO,FAD_oxidored,NAD_binding_8
WZS1_k127_6224664_3	204669.Acid345_1536	2.248e-92	322.0	COG0531@1|root,COG0531@2|Bacteria,3Y4PR@57723|Acidobacteria,2JJPB@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
WZS1_k127_6247246_6	243231.GSU3428	5.44e-26	117.0	COG1472@1|root,COG1472@2|Bacteria,1QUPT@1224|Proteobacteria,42VS9@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365
WZS1_k127_6247246_5	1379270.AUXF01000002_gene1595	4.599e-50	183.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WZS1_k127_6247246_3	1379270.AUXF01000002_gene1594	2.681e-63	221.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WZS1_k127_6247246_4	1379270.AUXF01000002_gene1593	3.575e-56	215.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	soxD	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
WZS1_k127_6247246_0	1379270.AUXF01000002_gene1592	6.953e-186	588.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
WZS1_k127_6247246_1	1379270.AUXF01000002_gene1591	2.438e-122	404.0	COG3258@1|root,COG3258@2|Bacteria,1ZUR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	-
WZS1_k127_6247246_2	886293.Sinac_5836	1.189e-63	221.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_6247673_1	398578.Daci_2532	4.319e-40	153.0	COG5397@1|root,COG5397@2|Bacteria	2|Bacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
WZS1_k127_6247673_0	1122185.N792_13005	5.902e-79	277.0	COG1737@1|root,COG1737@2|Bacteria,1NS7C@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6247673_2	1088721.NSU_1615	1.99e-30	126.0	COG1432@1|root,COG1432@2|Bacteria,1RJ15@1224|Proteobacteria,2UCYU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
WZS1_k127_6247673_3	926569.ANT_21410	5.615e-16	80.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
WZS1_k127_6248570_0	1379270.AUXF01000003_gene3408	1.631e-167	536.0	COG1220@1|root,COG1220@2|Bacteria,1ZSVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
WZS1_k127_6248570_1	1125863.JAFN01000001_gene2584	1.829e-120	394.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WZS1_k127_6248570_2	861299.J421_3957	4.594e-119	393.0	COG0404@1|root,COG0404@2|Bacteria,1ZTBZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WZS1_k127_6248570_3	861299.J421_3956	6.07e-33	136.0	COG0521@1|root,COG0521@2|Bacteria,1ZU2Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
WZS1_k127_6293250_0	1237149.C900_05550	4.412e-215	684.0	COG1506@1|root,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,47KF8@768503|Cytophagia	976|Bacteroidetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
WZS1_k127_6295538_1	379066.GAU_3928	9.843e-93	308.0	COG0035@1|root,COG0035@2|Bacteria,1ZT1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
WZS1_k127_6295538_0	861299.J421_1939	2.364e-152	495.0	COG1236@1|root,COG1236@2|Bacteria,1ZSP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
WZS1_k127_6295538_3	1828.JOKB01000035_gene691	9.999e-35	149.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria,4FUNH@85025|Nocardiaceae	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WZS1_k127_6295538_2	401526.TcarDRAFT_1680	4.883e-47	179.0	COG1055@1|root,COG1055@2|Bacteria,1TRZC@1239|Firmicutes,4H2X6@909932|Negativicutes	909932|Negativicutes	P	Dicarboxylate carrier	-	-	-	-	-	-	-	-	-	-	-	-	MatC_N
WZS1_k127_6296550_0	861299.J421_3848	7.431e-167	531.0	COG0443@1|root,COG0443@2|Bacteria,1ZT75@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WZS1_k127_6296550_1	861299.J421_3849	7.411e-114	385.0	COG0265@1|root,COG0265@2|Bacteria,1ZTG6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WZS1_k127_6313971_0	404589.Anae109_1720	1.177e-137	450.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,42N2B@68525|delta/epsilon subdivisions,2WJS9@28221|Deltaproteobacteria,2YVFZ@29|Myxococcales	28221|Deltaproteobacteria	S	Major facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WZS1_k127_6313971_1	56107.Cylst_2548	6.577e-23	105.0	2E3GU@1|root,32YFI@2|Bacteria,1G9HI@1117|Cyanobacteria,1HP28@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6313971_2	870187.Thini_2522	7.015e-06	53.0	2E3GU@1|root,32YFI@2|Bacteria,1NJ13@1224|Proteobacteria,1SI3B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6369591_2	861299.J421_2892	5.954e-62	219.0	COG1104@1|root,COG1104@2|Bacteria,1ZSXD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS1_k127_6369591_1	861299.J421_2891	2.989e-132	432.0	COG0482@1|root,COG0482@2|Bacteria,1ZST7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WZS1_k127_6369591_0	1379270.AUXF01000003_gene3560	6.429e-179	575.0	COG0855@1|root,COG0855@2|Bacteria,1ZT5F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WZS1_k127_6385627_1	1047013.AQSP01000115_gene352	1.095e-120	400.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6385627_0	1121374.KB891590_gene1705	1.599e-173	559.0	COG1757@1|root,COG1757@2|Bacteria,1MVDF@1224|Proteobacteria,1RS40@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
WZS1_k127_6385627_4	379066.GAU_3657	1.453e-15	82.0	2AU93@1|root,31JWF@2|Bacteria,1ZV74@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6385627_3	926560.KE387023_gene3374	2.432e-34	145.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_6385627_2	292.DM42_5334	3.826e-107	361.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2VRGQ@28216|Betaproteobacteria,1K6IJ@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_6396764_3	56107.Cylst_6310	1.435e-38	148.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1G3BJ@1117|Cyanobacteria,1HP35@1161|Nostocales	1117|Cyanobacteria	L	methylated-DNA- protein -cysteine S-methyltransferase	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
WZS1_k127_6396764_4	761193.Runsl_5485	1.893e-28	121.0	2A8XY@1|root,30Y1J@2|Bacteria,4NZRD@976|Bacteroidetes,47W74@768503|Cytophagia	976|Bacteroidetes	C	Photosynthetic reaction centre cytochrome C subunit	-	-	-	-	-	-	-	-	-	-	-	-	CytoC_RC
WZS1_k127_6396764_0	379066.GAU_1353	2.544e-264	837.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1ZT4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS1_k127_6396764_1	1379698.RBG1_1C00001G0830	8.629e-193	626.0	COG0480@1|root,COG0480@2|Bacteria,2NNQD@2323|unclassified Bacteria	2|Bacteria	J	elongation factor G	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WZS1_k127_6396764_2	1408418.JNJH01000001_gene2997	2.279e-50	184.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,2TUF8@28211|Alphaproteobacteria,2JPIH@204441|Rhodospirillales	204441|Rhodospirillales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
WZS1_k127_6404493_9	118166.JH976537_gene2732	2.354e-22	113.0	28KEA@1|root,2ZA0J@2|Bacteria	2|Bacteria	H	Sulfotransferase	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
WZS1_k127_6404493_8	748247.AZKH_0091	2.707e-54	205.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1R4VS@1224|Proteobacteria,2VQRB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6404493_7	627192.SLG_11520	3.076e-64	226.0	28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,2U8ZT@28211|Alphaproteobacteria,2K4I9@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6404493_5	557599.MKAN_23715	9.401e-79	279.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,234WY@1762|Mycobacteriaceae	201174|Actinobacteria	I	Alpha beta hydrolase	lipN	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
WZS1_k127_6404493_0	861299.J421_4300	1.125e-189	603.0	COG2072@1|root,COG2072@2|Bacteria,1ZV95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like
WZS1_k127_6404493_6	1223410.KN050846_gene205	2.098e-77	287.0	2DCFR@1|root,2ZDYQ@2|Bacteria,4NPNX@976|Bacteroidetes,1I27F@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
WZS1_k127_6404493_10	448385.sce0701	4.898e-09	63.0	2AG7T@1|root,316CY@2|Bacteria,1PXCS@1224|Proteobacteria,434FW@68525|delta/epsilon subdivisions,2WYTA@28221|Deltaproteobacteria,2Z0JQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6404493_3	882083.SacmaDRAFT_5691	3.975e-105	356.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4E14S@85010|Pseudonocardiales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
WZS1_k127_6404493_2	882083.SacmaDRAFT_5690	9.875e-121	412.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4DYYG@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS1_k127_6404493_4	882083.SacmaDRAFT_5689	6.339e-87	313.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4DZD5@85010|Pseudonocardiales	201174|Actinobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS1_k127_6404493_1	408672.NBCG_01838	3.317e-146	473.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DPKK@85009|Propionibacteriales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
WZS1_k127_6421932_0	1379270.AUXF01000004_gene2949	1.617e-177	578.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
WZS1_k127_6421932_2	518766.Rmar_1926	1.533e-19	91.0	COG0393@1|root,COG0393@2|Bacteria,4NQGB@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WZS1_k127_6421932_4	987059.RBXJA2T_16062	3.359e-11	67.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,2VTRD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WZS1_k127_6421932_1	1089552.KI911559_gene924	7.088e-82	286.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,2JQ6K@204441|Rhodospirillales	204441|Rhodospirillales	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WZS1_k127_6421932_3	379066.GAU_0433	8.598e-12	71.0	COG4783@1|root,COG4783@2|Bacteria,1ZT4T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6437667_1	1121377.KB906400_gene1356	3.005e-23	102.0	COG3173@1|root,COG3173@2|Bacteria,1WJ1R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
WZS1_k127_6437667_0	649638.Trad_0234	1.852e-27	117.0	COG0824@1|root,COG0824@2|Bacteria,1WKH6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
WZS1_k127_6437667_2	68170.KL590535_gene3743	2.074e-20	91.0	COG2210@1|root,COG2210@2|Bacteria,2IFXH@201174|Actinobacteria,4EABZ@85010|Pseudonocardiales	201174|Actinobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
WZS1_k127_6438696_3	379066.GAU_2730	5.927e-60	222.0	COG1533@1|root,COG1533@2|Bacteria,1ZUFM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS1_k127_6438696_0	756272.Plabr_3346	1.563e-162	527.0	COG0733@1|root,COG0733@2|Bacteria,2J29X@203682|Planctomycetes	203682|Planctomycetes	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
WZS1_k127_6438696_5	1121918.ARWE01000001_gene2296	2.963e-48	188.0	COG0389@1|root,COG0389@2|Bacteria,1RBTJ@1224|Proteobacteria,42QY9@68525|delta/epsilon subdivisions,2WMTI@28221|Deltaproteobacteria,43S6H@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	impB/mucB/samB family	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
WZS1_k127_6438696_6	1239962.C943_03877	1.233e-37	164.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
WZS1_k127_6438696_1	1379698.RBG1_1C00001G0607	1.16e-110	390.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
WZS1_k127_6438696_4	1340493.JNIF01000003_gene2146	5.449e-54	199.0	COG1595@1|root,COG1595@2|Bacteria,3Y589@57723|Acidobacteria	57723|Acidobacteria	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
WZS1_k127_6438696_2	1192034.CAP_4435	2.782e-74	258.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,2YUHA@29|Myxococcales	28221|Deltaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WZS1_k127_6447886_0	379066.GAU_0734	6.145e-200	640.0	COG0143@1|root,COG0143@2|Bacteria,1ZTDB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class I (M)	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
WZS1_k127_6447886_1	379066.GAU_0735	3.941e-95	325.0	COG1774@1|root,COG1774@2|Bacteria,1ZTE8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	PSP1 C-terminal conserved region	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
WZS1_k127_6447886_2	1121930.AQXG01000012_gene3191	0.0007058	43.0	COG0825@1|root,COG0825@2|Bacteria,4NEVU@976|Bacteroidetes,1IP0K@117747|Sphingobacteriia	976|Bacteroidetes	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
WZS1_k127_6461322_2	1379270.AUXF01000005_gene764	3.488e-123	405.0	COG2366@1|root,COG2366@2|Bacteria,1ZUMU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Penicillin amidase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
WZS1_k127_6461322_4	861299.J421_2796	1.484e-89	311.0	COG0024@1|root,COG0024@2|Bacteria,1ZTC1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WZS1_k127_6461322_11	670292.JH26_16850	1.624e-49	184.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,1JR6T@119045|Methylobacteriaceae	28211|Alphaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WZS1_k127_6461322_0	1379270.AUXF01000004_gene3012	2.308e-152	500.0	COG0201@1|root,COG0201@2|Bacteria,1ZSYZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WZS1_k127_6461322_12	1379270.AUXF01000004_gene3013	6.644e-47	173.0	COG0200@1|root,COG0200@2|Bacteria,1ZTP0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
WZS1_k127_6461322_21	861299.J421_2792	8.48e-19	91.0	COG1841@1|root,COG1841@2|Bacteria,1ZU4E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein L30p/L7e	-	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
WZS1_k127_6461322_7	379066.GAU_0890	3.561e-69	250.0	COG0098@1|root,COG0098@2|Bacteria,1ZTHD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
WZS1_k127_6461322_17	351607.Acel_0322	7.539e-28	124.0	COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4ESW2@85013|Frankiales	201174|Actinobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
WZS1_k127_6461322_9	379066.GAU_0888	8.541e-61	214.0	COG0097@1|root,COG0097@2|Bacteria,1ZTJ8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
WZS1_k127_6461322_15	177437.HRM2_36120	5.138e-34	146.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2MJZV@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
WZS1_k127_6461322_19	700015.Corgl_1317	1.971e-21	97.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,4CWG8@84998|Coriobacteriia	84998|Coriobacteriia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
WZS1_k127_6461322_5	861299.J421_2786	6.867e-80	273.0	COG0094@1|root,COG0094@2|Bacteria,1ZSTZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
WZS1_k127_6461322_14	379066.GAU_0884	7.283e-37	143.0	COG0198@1|root,COG0198@2|Bacteria,1ZTRE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
WZS1_k127_6461322_8	1379270.AUXF01000004_gene3023	1.347e-61	213.0	COG0093@1|root,COG0093@2|Bacteria,1ZTPT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
WZS1_k127_6461322_20	1379270.AUXF01000004_gene3024	2.746e-20	96.0	COG0186@1|root,COG0186@2|Bacteria,1ZU1B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
WZS1_k127_6461322_22	379066.GAU_0881	2.421e-11	65.0	COG0255@1|root,COG0255@2|Bacteria,1ZU5T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal L29 protein	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
WZS1_k127_6461322_10	861299.J421_2781	3.573e-58	205.0	COG0197@1|root,COG0197@2|Bacteria,1ZTKB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
WZS1_k127_6461322_3	861299.J421_2780	2.055e-100	342.0	COG0092@1|root,COG0092@2|Bacteria,1ZTFT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WZS1_k127_6461322_16	1379270.AUXF01000004_gene3028	1.437e-31	126.0	COG0091@1|root,COG0091@2|Bacteria,1ZTVF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
WZS1_k127_6461322_13	1379270.AUXF01000004_gene3029	1.051e-39	150.0	COG0185@1|root,COG0185@2|Bacteria,1ZU04@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
WZS1_k127_6461322_1	1379270.AUXF01000004_gene3030	7.867e-130	419.0	COG0090@1|root,COG0090@2|Bacteria,1ZSUP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WZS1_k127_6461322_18	861299.J421_2776	2.182e-23	102.0	COG0089@1|root,COG0089@2|Bacteria,1ZTWN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
WZS1_k127_6461322_6	861299.J421_2775	1.015e-76	265.0	COG0088@1|root,COG0088@2|Bacteria,1ZSSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
WZS1_k127_6469946_6	1379270.AUXF01000006_gene212	9.202e-41	152.0	COG0057@1|root,COG0057@2|Bacteria,1ZSTF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WZS1_k127_6469946_7	379066.GAU_1680	5.094e-39	155.0	COG1040@1|root,COG1040@2|Bacteria,1ZTS5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
WZS1_k127_6469946_10	1380390.JIAT01000017_gene5301	1.045e-30	140.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CQ8W@84995|Rubrobacteria	84995|Rubrobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
WZS1_k127_6469946_8	861299.J421_3313	1.392e-37	146.0	COG0394@1|root,COG0394@2|Bacteria,1ZTSE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WZS1_k127_6469946_4	861299.J421_3314	5.531e-51	198.0	COG0009@1|root,COG0009@2|Bacteria,1ZT3D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Telomere recombination	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
WZS1_k127_6469946_5	861299.J421_3315	3.845e-47	186.0	COG1211@1|root,COG1211@2|Bacteria,1ZSTV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
WZS1_k127_6469946_1	861299.J421_3316	2e-158	514.0	COG1066@1|root,COG1066@2|Bacteria,1ZSYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	ATPase
WZS1_k127_6469946_0	1379270.AUXF01000006_gene205	4.871e-163	526.0	COG0305@1|root,COG0305@2|Bacteria,1ZSMZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WZS1_k127_6469946_2	1379270.AUXF01000006_gene204	7.417e-65	231.0	COG1573@1|root,COG1573@2|Bacteria,1ZTG5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WZS1_k127_6469946_11	1379270.AUXF01000006_gene203	3.151e-14	74.0	28VAR@1|root,2ZHDJ@2|Bacteria,1ZU25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
WZS1_k127_6469946_3	861299.J421_3321	7.547e-56	208.0	COG0194@1|root,COG0194@2|Bacteria,1ZTV7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WZS1_k127_6469946_9	269799.Gmet_2328	2.421e-33	133.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,43TKR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Stationary phase survival protein, YicC family, YicC_N and DUF1732 domain-containing	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
WZS1_k127_649787_2	861299.J421_2920	2.998e-86	287.0	COG1012@1|root,COG1012@2|Bacteria,1ZST9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Aldehyde dehydrogenase family	-	-	-	ko:K22187	ko00040,map00040	-	R11768	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
WZS1_k127_649787_0	861299.J421_2922	1.262e-132	428.0	COG0568@1|root,COG0568@2|Bacteria,1ZSR6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS1_k127_649787_4	861299.J421_2925	6.038e-50	183.0	COG1666@1|root,COG1666@2|Bacteria,1ZTNB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Protein of unknown function (DUF520)	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
WZS1_k127_649787_3	861299.J421_2928	1.232e-56	215.0	COG2385@1|root,COG2385@2|Bacteria,1ZT25@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
WZS1_k127_649787_1	379066.GAU_1177	2.143e-88	308.0	COG0673@1|root,COG0673@2|Bacteria,1ZSV9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WZS1_k127_6518585_5	1379270.AUXF01000006_gene26	1.221e-20	106.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WZS1_k127_6518585_0	861299.J421_3546	2.597e-154	518.0	COG2986@1|root,COG2986@2|Bacteria,1ZTEG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WZS1_k127_6518585_4	1519464.HY22_00155	4.373e-27	130.0	COG1452@1|root,COG1452@2|Bacteria,1FD7H@1090|Chlorobi	1090|Chlorobi	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6518585_2	861299.J421_3548	2.645e-46	193.0	COG0805@1|root,COG0805@2|Bacteria,1ZTHN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WZS1_k127_6518585_6	411464.DESPIG_01432	2.915e-07	61.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,2MC83@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
WZS1_k127_6518585_3	1379270.AUXF01000006_gene18	6.721e-33	137.0	COG2885@1|root,COG2885@2|Bacteria,1ZTSM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
WZS1_k127_6518585_1	861299.J421_3551	4.521e-74	263.0	COG0823@1|root,COG0823@2|Bacteria,1ZTBK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WZS1_k127_6555489_0	1237149.C900_02066	3.579e-68	239.0	COG0076@1|root,COG0076@2|Bacteria,4NGZB@976|Bacteroidetes	976|Bacteroidetes	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
WZS1_k127_6555489_2	290317.Cpha266_2735	1.613e-32	143.0	COG0705@1|root,COG0705@2|Bacteria,1FDF1@1090|Chlorobi	1090|Chlorobi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WZS1_k127_6555489_1	1379270.AUXF01000002_gene1118	5.655e-45	171.0	2CDZB@1|root,3340J@2|Bacteria,1ZU24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6555489_3	234267.Acid_6501	3.071e-10	61.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WZS1_k127_6563895_0	861299.J421_2609	6.042e-177	564.0	COG0156@1|root,COG0156@2|Bacteria,1ZST6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Beta-eliminating lyase	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS1_k127_6563895_1	62928.azo3258	2.059e-62	232.0	COG1216@1|root,COG1216@2|Bacteria,1QVCS@1224|Proteobacteria,2VYMF@28216|Betaproteobacteria	1224|Proteobacteria	S	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WZS1_k127_6563895_2	1347086.CCBA010000010_gene1693	4.977e-51	194.0	COG1181@1|root,COG1181@2|Bacteria,1TVZY@1239|Firmicutes,4HEFM@91061|Bacilli	91061|Bacilli	M	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp,ATP-grasp_3,CPSase_L_D2
WZS1_k127_6563964_4	379066.GAU_2503	7.366e-59	209.0	COG1220@1|root,COG1220@2|Bacteria,1ZSVP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
WZS1_k127_6563964_3	1379270.AUXF01000003_gene3407	1.674e-76	260.0	COG5405@1|root,COG5405@2|Bacteria,1ZSVH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
WZS1_k127_6563964_2	379066.GAU_2507	5.544e-83	295.0	COG4974@1|root,COG4974@2|Bacteria,1ZT3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS1_k127_6563964_0	1158318.ATXC01000001_gene334	2.284e-136	449.0	COG1206@1|root,COG1206@2|Bacteria,2G3NY@200783|Aquificae	200783|Aquificae	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
WZS1_k127_6563964_5	861299.J421_3973	7.885e-30	124.0	COG0703@1|root,COG0703@2|Bacteria,1ZTXW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
WZS1_k127_6563964_1	861299.J421_3974	6.609e-133	432.0	COG0082@1|root,COG0082@2|Bacteria,1ZT39@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
WZS1_k127_6607701_1	379066.GAU_2607	1.212e-74	260.0	COG0612@1|root,COG0612@2|Bacteria,1ZSU0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS1_k127_6607701_0	861299.J421_4211	1.382e-127	419.0	COG0457@1|root,COG0457@2|Bacteria,1ZSYB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
WZS1_k127_6620742_2	861299.J421_2765	8.774e-06	49.0	COG0244@1|root,COG0244@2|Bacteria,1ZTQI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WZS1_k127_6620742_1	861299.J421_2766	1.683e-48	176.0	COG0222@1|root,COG0222@2|Bacteria,1ZTTC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WZS1_k127_6620742_0	861299.J421_2767	0.0	1364.0	COG0085@1|root,COG0085@2|Bacteria,1ZSQH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WZS1_k127_6635249_1	861299.J421_2486	3.655e-34	141.0	COG1215@1|root,COG1215@2|Bacteria,1ZUUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6635249_0	861299.J421_2617	1.429e-139	454.0	COG1092@1|root,COG1092@2|Bacteria,1ZT8Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WZS1_k127_6651173_1	1123508.JH636441_gene3431	6.143e-75	277.0	COG2199@1|root,COG5002@1|root,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
WZS1_k127_6651173_0	861299.J421_4119	9.506e-141	454.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS1_k127_6662041_7	379066.GAU_2715	7.525e-06	49.0	COG0405@1|root,COG0405@2|Bacteria,1ZT8M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WZS1_k127_6662041_1	1028800.RG540_PA12910	8.466e-84	292.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,2UHB3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WZS1_k127_6662041_5	264462.Bd1337	2.409e-36	144.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,430NN@68525|delta/epsilon subdivisions,2MT6T@213481|Bdellovibrionales,2WVYS@28221|Deltaproteobacteria	213481|Bdellovibrionales	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
WZS1_k127_6662041_2	861299.J421_2173	5.551e-66	235.0	COG0457@1|root,COG0457@2|Bacteria	861299.J421_2173|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6662041_3	649638.Trad_0059	1.329e-52	193.0	COG3153@1|root,COG3153@2|Bacteria,1WJBH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS1_k127_6662041_0	1122222.AXWR01000002_gene2143	1.804e-174	558.0	COG0160@1|root,COG0160@2|Bacteria,1WJ8V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WZS1_k127_6662041_6	326427.Cagg_3417	5.802e-32	143.0	COG1574@1|root,COG1574@2|Bacteria,2G85Y@200795|Chloroflexi,37716@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS1_k127_666670_1	861299.J421_2666	2.767e-106	353.0	COG0508@1|root,COG0508@2|Bacteria,1ZSYJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WZS1_k127_666670_0	861299.J421_2662	4.304e-192	609.0	COG1249@1|root,COG1249@2|Bacteria,1ZT95@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
WZS1_k127_666670_3	861299.J421_2661	5.057e-67	244.0	COG0321@1|root,COG0321@2|Bacteria,1ZTM1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WZS1_k127_666670_2	562970.Btus_0516	6.71e-69	240.0	COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,278B0@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase molybdopterin binding domain	yuiH	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
WZS1_k127_666670_4	1382304.JNIL01000001_gene1413	1.112e-10	64.0	COG0129@1|root,COG0129@2|Bacteria,1U56J@1239|Firmicutes,4HD31@91061|Bacilli	91061|Bacilli	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
WZS1_k127_672322_5	861299.J421_3093	2.683e-30	123.0	COG0787@1|root,COG0787@2|Bacteria,1ZT57@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WZS1_k127_672322_3	861299.J421_3092	3.743e-75	262.0	COG1694@1|root,COG3956@2|Bacteria,1ZSZH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
WZS1_k127_672322_0	379066.GAU_1447	2.441e-178	567.0	COG0017@1|root,COG0017@2|Bacteria,1ZSTX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WZS1_k127_672322_2	1232410.KI421412_gene38	1.659e-84	306.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2WKC7@28221|Deltaproteobacteria,43UWU@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
WZS1_k127_672322_1	1121448.DGI_0733	2.267e-104	345.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2M8FK@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM ABC transporter related	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
WZS1_k127_672322_4	1283300.ATXB01000002_gene2869	4.807e-33	143.0	COG1463@1|root,COG1463@2|Bacteria,1Q6ZU@1224|Proteobacteria,1S6SW@1236|Gammaproteobacteria,1XGZV@135618|Methylococcales	135618|Methylococcales	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
WZS1_k127_672322_6	290397.Adeh_3139	2.322e-23	106.0	COG3009@1|root,COG3009@2|Bacteria,1N8BW@1224|Proteobacteria,42UW2@68525|delta/epsilon subdivisions,2WQFD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
WZS1_k127_672322_7	1191523.MROS_2048	2.562e-20	105.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
WZS1_k127_6727349_2	1379270.AUXF01000002_gene1111	2.668e-53	192.0	COG3177@1|root,COG3177@2|Bacteria,1ZVA2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
WZS1_k127_6727349_4	246197.MXAN_1633	7.952e-21	100.0	COG1670@1|root,COG1670@2|Bacteria,1RKT9@1224|Proteobacteria,42VCK@68525|delta/epsilon subdivisions,2WS7R@28221|Deltaproteobacteria,2Z14V@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	rimJ2	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WZS1_k127_6727349_1	1121013.P873_13790	8.033e-136	449.0	COG1680@1|root,COG1680@2|Bacteria,1R49D@1224|Proteobacteria,1S4AC@1236|Gammaproteobacteria,1X72E@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WZS1_k127_6727349_0	138119.DSY1012	1.821e-186	589.0	COG0376@1|root,COG0376@2|Bacteria,1TQDA@1239|Firmicutes,24DM7@186801|Clostridia,260RF@186807|Peptococcaceae	186801|Clostridia	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
WZS1_k127_6738322_8	391625.PPSIR1_16360	6.76e-32	134.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WZS1_k127_6738322_7	861299.J421_2177	3.078e-44	166.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
WZS1_k127_6738322_4	204669.Acid345_1820	6.339e-91	310.0	COG0549@1|root,COG0549@2|Bacteria,3Y7CP@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS1_k127_6738322_1	880073.Calab_0633	7.587e-187	595.0	COG2403@1|root,COG2403@2|Bacteria,2NNTB@2323|unclassified Bacteria	2|Bacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	cobW
WZS1_k127_6738322_2	518766.Rmar_2384	2.707e-108	368.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
WZS1_k127_6738322_0	861299.J421_0968	6.352e-302	949.0	COG0308@1|root,COG0308@2|Bacteria,1ZUSR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ERAP1-like C-terminal domain	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
WZS1_k127_6738322_6	215803.DB30_3805	1.592e-62	235.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2YXUC@29|Myxococcales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS1_k127_6738322_5	1089553.Tph_c27670	4.95e-67	235.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548,ko:K14084	ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230	M00017,M00563	R00946,R09124,R09365	RC00035,RC00113,RC00732,RC01241,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
WZS1_k127_6738322_3	1047013.AQSP01000134_gene1338	7.182e-92	327.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
WZS1_k127_6779240_1	1415780.JPOG01000001_gene1115	5.801e-135	443.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1X3MQ@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WZS1_k127_6779240_2	1134445.AJJM01000012_gene2439	4.009e-12	75.0	COG2137@1|root,COG2137@2|Bacteria,2GMRF@201174|Actinobacteria	201174|Actinobacteria	S	regulatory protein RecX	recX	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WZS1_k127_6779240_0	1379270.AUXF01000006_gene42	2.078e-139	446.0	COG0468@1|root,COG0468@2|Bacteria,1ZT78@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WZS1_k127_6782701_2	1121946.AUAX01000016_gene4690	2.164e-26	115.0	COG2020@1|root,COG2020@2|Bacteria,2IP2M@201174|Actinobacteria,4DGDW@85008|Micromonosporales	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WZS1_k127_6782701_1	204669.Acid345_3040	1.083e-137	454.0	COG3653@1|root,COG3653@2|Bacteria,3Y3Q2@57723|Acidobacteria,2JJ0K@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_6782701_0	1379270.AUXF01000002_gene1710	3.802e-224	714.0	COG3733@1|root,COG3733@2|Bacteria,1ZUIF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Copper amine oxidase, N2 domain	-	-	1.4.3.21	ko:K00276	ko00260,ko00350,ko00360,ko00410,ko00950,ko00960,ko01100,ko01110,map00260,map00350,map00360,map00410,map00950,map00960,map01100,map01110	-	R02382,R02529,R02613,R03139,R04027,R04300,R06154,R06740	RC00062,RC00189,RC00676,RC01052	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxid,Cu_amine_oxidN2,Cu_amine_oxidN3
WZS1_k127_6798963_1	1123401.JHYQ01000005_gene245	1.157e-13	85.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,1RNTJ@1236|Gammaproteobacteria,462CC@72273|Thiotrichales	72273|Thiotrichales	C	Hydrogenase (NiFe) small subunit HydA	-	-	1.12.5.1	ko:K05927	-	-	-	-	ko00000,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
WZS1_k127_6798963_2	945713.IALB_0021	4.137e-13	82.0	COG1404@1|root,COG3303@1|root,COG1404@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Calx-beta,Cytochrom_C552,Cytochrome_C554,FlgD_ig,Paired_CXXCH_1,VCBS
WZS1_k127_6798963_0	404589.Anae109_0112	5.309e-17	93.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6830201_2	1379270.AUXF01000004_gene3069	8.573e-74	258.0	28M0D@1|root,2ZAFE@2|Bacteria,1ZUP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
WZS1_k127_6830201_1	379066.GAU_0826	8.026e-101	347.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS1_k127_6830201_3	316067.Geob_0548	1.619e-06	61.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WZS1_k127_6830201_0	861299.J421_2748	2.101e-286	895.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WZS1_k127_6830658_0	1379270.AUXF01000004_gene3330	1.321e-243	767.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1ZT6C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
WZS1_k127_6830658_1	1330700.JQNC01000001_gene2140	6.489e-127	421.0	COG1404@1|root,COG1404@2|Bacteria,1WIDU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	3.4.21.111	ko:K20754	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Inhibitor_I9,Peptidase_S8
WZS1_k127_6830658_2	1121272.KB903249_gene1700	7.186e-109	376.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2GJYH@201174|Actinobacteria,4DBUI@85008|Micromonosporales	201174|Actinobacteria	M	Peptidase inhibitor I9	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,P_proprotein,Peptidase_S8
WZS1_k127_6830658_3	1463857.JOFZ01000005_gene3188	2.142e-30	122.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
WZS1_k127_6866830_0	861299.J421_4131	0.0	1019.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
WZS1_k127_6866830_3	1121405.dsmv_3081	3.543e-45	169.0	2C8DW@1|root,32RKY@2|Bacteria,1MZUD@1224|Proteobacteria,432NJ@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function (DUF3597)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3597
WZS1_k127_6866830_2	880073.Calab_2396	6.234e-172	556.0	COG0205@1|root,COG0205@2|Bacteria,2NNXU@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135	2.7.1.11,2.7.1.90	ko:K00850,ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WZS1_k127_6866830_4	861299.J421_6270	4.067e-10	72.0	2DJDE@1|root,305RC@2|Bacteria,1ZV7X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6866830_1	1340493.JNIF01000004_gene829	1.002e-226	711.0	COG0591@1|root,COG0591@2|Bacteria,3Y42K@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
WZS1_k127_6880326_1	1122621.ATZA01000004_gene1240	9.512e-37	155.0	COG0612@1|root,COG0612@2|Bacteria,4NEPT@976|Bacteroidetes,1IQD7@117747|Sphingobacteriia	976|Bacteroidetes	S	Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS1_k127_6880326_0	1121015.N789_14390	1.139e-173	556.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,1RRK7@1236|Gammaproteobacteria,1X4CC@135614|Xanthomonadales	135614|Xanthomonadales	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
WZS1_k127_6880326_2	861299.J421_3334	9.844e-35	142.0	COG1228@1|root,COG1228@2|Bacteria,1ZTI7@142182|Gemmatimonadetes	861299.J421_3334|-	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6893037_0	518766.Rmar_1876	8.546e-73	264.0	COG2027@1|root,COG2027@2|Bacteria,4NGIQ@976|Bacteroidetes,1FIVK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WZS1_k127_6893037_1	379066.GAU_0608	1.454e-06	55.0	COG4775@1|root,COG4775@2|Bacteria,1ZSY7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WZS1_k127_6918965_1	1502852.FG94_02223	1.723e-25	123.0	COG1228@1|root,COG4946@1|root,COG1228@2|Bacteria,COG4946@2|Bacteria,1QVGM@1224|Proteobacteria	1224|Proteobacteria	Q	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WZS1_k127_6918965_0	379066.GAU_2666	0.0	1033.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1ZUMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	QU	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WZS1_k127_6934183_0	861299.J421_2997	5.503e-259	812.0	COG0441@1|root,COG0441@2|Bacteria,1ZT2I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WZS1_k127_6941444_2	861299.J421_4357	2.876e-56	206.0	COG0577@1|root,COG0577@2|Bacteria,1ZURT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS1_k127_6941444_1	861299.J421_4356	4.413e-76	274.0	COG1136@1|root,COG1136@2|Bacteria,1ZUKE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS1_k127_6941444_0	861299.J421_4355	2.571e-106	364.0	2AETJ@1|root,314QN@2|Bacteria,1ZU8F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6941444_3	1430331.EP10_08615	6.85e-17	87.0	COG2318@1|root,COG2318@2|Bacteria,1V8A0@1239|Firmicutes,4HIW8@91061|Bacilli,1WGBX@129337|Geobacillus	91061|Bacilli	S	Protein of unknown function (DUF1569)	yuaE	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS1_k127_6959445_2	1379270.AUXF01000001_gene2556	8.893e-73	251.0	COG0515@1|root,COG0515@2|Bacteria	1379270.AUXF01000001_gene2556|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6959445_10	479435.Kfla_0170	2.243e-30	126.0	2E31H@1|root,32Y1W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6959445_8	37659.JNLN01000001_gene441	2.677e-35	138.0	2D5AS@1|root,32TIN@2|Bacteria,1VA4E@1239|Firmicutes,24JJQ@186801|Clostridia,36JKZ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B561
WZS1_k127_6959445_1	379066.GAU_3732	7.523e-75	267.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
WZS1_k127_6959445_11	251229.Chro_5550	1.029e-21	110.0	COG1462@1|root,COG1462@2|Bacteria,1G2XT@1117|Cyanobacteria,3VMNX@52604|Pleurocapsales	1117|Cyanobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
WZS1_k127_6959445_13	269799.Gmet_2185	5.911e-06	58.0	COG2010@1|root,COG4733@1|root,COG2010@2|Bacteria,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
WZS1_k127_6959445_16	1157490.EL26_22475	0.0004299	53.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli,2780U@186823|Alicyclobacillaceae	91061|Bacilli	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WZS1_k127_6959445_15	1117647.M5M_16515	7.423e-05	55.0	COG4733@1|root,COG4733@2|Bacteria,1ND1G@1224|Proteobacteria,1SGKI@1236|Gammaproteobacteria,1J7JP@118884|unclassified Gammaproteobacteria	2|Bacteria	S	Carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Phage-tail_3,SLH,fn3
WZS1_k127_6959445_0	324057.Pjdr2_6263	9.289e-182	583.0	COG3653@1|root,COG3653@2|Bacteria,1TSGD@1239|Firmicutes,4HBQ4@91061|Bacilli,26VUM@186822|Paenibacillaceae	91061|Bacilli	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_6959445_9	1123242.JH636434_gene4248	1.501e-34	136.0	COG0640@1|root,COG0640@2|Bacteria,2J0I4@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
WZS1_k127_6959445_5	1123073.KB899242_gene1301	5.271e-44	171.0	298RU@1|root,3059D@2|Bacteria,1QRA7@1224|Proteobacteria,1TDHB@1236|Gammaproteobacteria,1XAQM@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6959445_6	1123508.JH636443_gene4834	1.101e-42	164.0	COG3832@1|root,COG3832@2|Bacteria,2J11K@203682|Planctomycetes	203682|Planctomycetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WZS1_k127_6959445_12	522306.CAP2UW1_2443	4.941e-18	94.0	2DYKW@1|root,34AA1@2|Bacteria,1P0V8@1224|Proteobacteria,2W4PE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6959445_4	1121861.KB899917_gene3703	2.137e-51	191.0	2E3HM@1|root,32YG7@2|Bacteria,1RFJA@1224|Proteobacteria,2U8PF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6959445_3	391037.Sare_4647	6.069e-57	206.0	COG1670@1|root,COG1670@2|Bacteria,2IQ5X@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS1_k127_6959445_7	530564.Psta_4322	7.792e-40	149.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
WZS1_k127_6963312_2	1266909.AUAG01000043_gene2579	7.952e-79	274.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,1RMSS@1236|Gammaproteobacteria,1WWPX@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
WZS1_k127_6963312_0	861299.J421_1663	3.415e-149	480.0	COG3191@1|root,COG3191@2|Bacteria,1ZT47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WZS1_k127_6963312_1	379066.GAU_0868	1.581e-134	440.0	COG0381@1|root,COG0381@2|Bacteria,1ZTEU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	UDP-N-acetylglucosamine 2-epimerase	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
WZS1_k127_6963312_3	861299.J421_4216	1.804e-07	64.0	2E6HX@1|root,33155@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_6976200_1	861299.J421_6088	9.092e-153	491.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_6976200_5	111780.Sta7437_4372	9.965e-38	145.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,3VK9B@52604|Pleurocapsales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WZS1_k127_6976200_6	861299.J421_3337	1.617e-29	121.0	COG0261@1|root,COG0261@2|Bacteria,1ZTS8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WZS1_k127_6976200_3	316067.Geob_1241	2.053e-113	386.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
WZS1_k127_6976200_0	861299.J421_3340	3.875e-185	588.0	COG1960@1|root,COG1960@2|Bacteria,1ZSVZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	ko:K18244	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS1_k127_6976200_2	204669.Acid345_2395	1.102e-125	430.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8
WZS1_k127_6976200_4	1379270.AUXF01000006_gene190	1.424e-101	350.0	COG0514@1|root,COG0514@2|Bacteria,1ZSNS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
WZS1_k127_6990373_0	880073.Calab_1611	2.889e-161	518.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS1_k127_6990373_2	1191523.MROS_1568	8.507e-63	225.0	COG0509@1|root,COG0745@1|root,COG0509@2|Bacteria,COG0745@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H,Response_reg
WZS1_k127_6990373_1	1191523.MROS_1567	4.816e-135	440.0	COG0509@1|root,COG2204@1|root,COG0509@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GAF_2,GCV_H,Response_reg
WZS1_k127_6997430_1	305700.B447_02798	1.964e-39	151.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2VIB9@28216|Betaproteobacteria,2KU7E@206389|Rhodocyclales	206389|Rhodocyclales	G	polysaccharide deactylase family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
WZS1_k127_6997430_3	1184609.KILIM_119_00020	1.33e-12	81.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4F7KB@85018|Dermatophilaceae	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS1_k127_6997430_0	272134.KB731324_gene1964	1.713e-99	350.0	COG1208@1|root,COG1208@2|Bacteria,1G4AN@1117|Cyanobacteria,1H8TU@1150|Oscillatoriales	1117|Cyanobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
WZS1_k127_6997430_2	861299.J421_2475	5.711e-37	155.0	COG4767@1|root,COG4767@2|Bacteria,1ZU1C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WZS1_k127_7018046_1	861299.J421_0779	2.156e-87	302.0	COG0652@1|root,COG0652@2|Bacteria,1ZTYX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
WZS1_k127_7018046_3	234267.Acid_4907	4.873e-41	162.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WZS1_k127_7018046_4	760192.Halhy_4503	9.594e-38	148.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
WZS1_k127_7018046_0	765420.OSCT_0396	2.006e-89	303.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WZS1_k127_7018046_2	655815.ZPR_2563	1.871e-62	220.0	COG2355@1|root,COG2355@2|Bacteria,4NEBG@976|Bacteroidetes,1HXGJ@117743|Flavobacteriia	976|Bacteroidetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273,ko:K01274	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_C26,Peptidase_M19
WZS1_k127_7029483_1	861299.J421_2688	1.032e-78	267.0	COG1435@1|root,COG1435@2|Bacteria,1ZTB2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WZS1_k127_7029483_2	1379270.AUXF01000004_gene3113	5.938e-52	194.0	COG0237@1|root,COG0237@2|Bacteria,1ZTM2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WZS1_k127_7029483_3	1379270.AUXF01000004_gene3114	1.466e-46	171.0	COG0509@1|root,COG0509@2|Bacteria,1ZTWD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WZS1_k127_7029483_0	861299.J421_2685	0.0	1255.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1ZSUZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
WZS1_k127_7029483_4	861299.J421_2684	2.18e-20	96.0	COG0095@1|root,COG0095@2|Bacteria,1ZTY2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WZS1_k127_7041560_0	404589.Anae109_3731	4.018e-102	355.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
WZS1_k127_7041560_1	517418.Ctha_1226	1.315e-35	150.0	COG3204@1|root,COG3204@2|Bacteria,1FEUK@1090|Chlorobi	1090|Chlorobi	S	SdiA-regulated	-	-	-	-	-	-	-	-	-	-	-	-	SdiA-regulated
WZS1_k127_7067516_2	861299.J421_2017	3.123e-136	441.0	COG0841@1|root,COG0841@2|Bacteria,1ZTEK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
WZS1_k127_7067516_5	379066.GAU_3091	2.608e-86	307.0	COG0845@1|root,COG0845@2|Bacteria,1ZSR2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
WZS1_k127_7067516_6	379066.GAU_3092	5.931e-85	304.0	COG1538@1|root,COG1538@2|Bacteria,1ZSR9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
WZS1_k127_7067516_9	861299.J421_2014	1.18e-36	151.0	COG1309@1|root,COG1309@2|Bacteria,1ZTWV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS1_k127_7067516_1	861299.J421_6095	1.874e-145	484.0	COG0531@1|root,COG0531@2|Bacteria,1ZUQJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WZS1_k127_7067516_8	379066.GAU_2027	2.8e-64	229.0	COG1802@1|root,COG1802@2|Bacteria,1ZUBC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WZS1_k127_7067516_0	861299.J421_2266	2.268e-219	696.0	COG3653@1|root,COG3653@2|Bacteria,1ZTDH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_7067516_7	1122927.KB895420_gene4153	8.158e-73	265.0	COG4188@1|root,COG4188@2|Bacteria,1UZMD@1239|Firmicutes,4HEFX@91061|Bacilli,26SNS@186822|Paenibacillaceae	91061|Bacilli	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
WZS1_k127_7067516_11	1379270.AUXF01000001_gene2088	4.991e-12	72.0	2DDI2@1|root,2ZI6I@2|Bacteria,1ZVAF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7067516_3	861299.J421_6089	6.662e-102	350.0	COG1073@1|root,COG1680@1|root,COG1073@2|Bacteria,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Beta-lactamase,DUF3471,Hydrolase_4
WZS1_k127_7067516_10	446462.Amir_1210	5.584e-19	87.0	COG4877@1|root,COG4877@2|Bacteria,2GQV1@201174|Actinobacteria,4E6UQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7067516_4	1379270.AUXF01000001_gene2023	3.589e-97	321.0	COG0330@1|root,COG0330@2|Bacteria,1ZUIA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WZS1_k127_7095114_1	929713.NIASO_18960	3.292e-11	73.0	COG0671@1|root,COG0671@2|Bacteria,4NF9W@976|Bacteroidetes,1IRBB@117747|Sphingobacteriia	976|Bacteroidetes	I	SPTR Phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WZS1_k127_7095114_0	861299.J421_2219	2.558e-164	545.0	COG1629@1|root,COG4771@2|Bacteria,1ZT27@142182|Gemmatimonadetes	861299.J421_2219|-	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7136091_1	518766.Rmar_1178	2.028e-165	541.0	COG3591@1|root,COG3591@2|Bacteria,4NEAK@976|Bacteroidetes,1FJT8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Peptidase S46	dpp7	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008239,GO:0009056,GO:0009279,GO:0009986,GO:0009987,GO:0016020,GO:0016049,GO:0016787,GO:0017171,GO:0019538,GO:0019867,GO:0030154,GO:0030312,GO:0030313,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0040007,GO:0042277,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044462,GO:0044464,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048869,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
WZS1_k127_7136091_3	215803.DB30_4330	2.168e-05	55.0	COG1309@1|root,COG1309@2|Bacteria,1NBI7@1224|Proteobacteria,43944@68525|delta/epsilon subdivisions,2X4A3@28221|Deltaproteobacteria,2YYKP@29|Myxococcales	28221|Deltaproteobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	ko:K02167	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_6,TetR_N
WZS1_k127_7136091_0	452637.Oter_2456	7.065e-261	818.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	414999|Opitutae	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
WZS1_k127_7136091_2	278957.ABEA03000117_gene1100	1.195e-25	108.0	COG1762@1|root,COG1762@2|Bacteria,46YU0@74201|Verrucomicrobia,3K7XN@414999|Opitutae	414999|Opitutae	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
WZS1_k127_7149858_1	861299.J421_2988	1.319e-147	490.0	COG0457@1|root,COG0659@1|root,COG0457@2|Bacteria,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7149858_0	861299.J421_2989	5.871e-175	568.0	COG0138@1|root,COG0138@2|Bacteria,1ZT6N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WZS1_k127_7149858_2	861299.J421_2990	2.986e-53	194.0	COG0299@1|root,COG0299@2|Bacteria,1ZTKJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
WZS1_k127_7149858_3	596151.DesfrDRAFT_3749	3.651e-09	59.0	2DBAY@1|root,2Z84S@2|Bacteria,1R7V4@1224|Proteobacteria,42MQE@68525|delta/epsilon subdivisions,2WJGC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1835
WZS1_k127_7155568_7	525903.Taci_1212	1.87e-54	197.0	COG1490@1|root,COG1490@2|Bacteria,3TB52@508458|Synergistetes	508458|Synergistetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WZS1_k127_7155568_8	379731.PST_0241	2.499e-47	172.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,1S5VQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
WZS1_k127_7155568_6	748247.AZKH_p0043	1.307e-70	246.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria,2KWE4@206389|Rhodocyclales	206389|Rhodocyclales	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WZS1_k127_7155568_2	748247.AZKH_p0046	1.089e-180	573.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,2KUSU@206389|Rhodocyclales	206389|Rhodocyclales	P	COG0798 Arsenite efflux pump ACR3 and related permeases	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WZS1_k127_7155568_9	1158292.JPOE01000002_gene3584	3.444e-33	145.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,2VSJE@28216|Betaproteobacteria,1KP2R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Arsenical resistance operon trans-acting repressor ArsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
WZS1_k127_7155568_1	497321.C664_07193	2.221e-244	769.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,2VK65@28216|Betaproteobacteria,2KUEH@206389|Rhodocyclales	206389|Rhodocyclales	P	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
WZS1_k127_7155568_0	379066.GAU_2427	2.18e-262	820.0	COG0449@1|root,COG0449@2|Bacteria,1ZSTI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WZS1_k127_7155568_4	861299.J421_3894	2.603e-155	505.0	COG1109@1|root,COG1109@2|Bacteria,1ZSNW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WZS1_k127_7155568_5	861299.J421_3895	9.475e-90	310.0	COG3437@1|root,COG3437@2|Bacteria,1ZSX2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
WZS1_k127_7155568_3	379066.GAU_2431	1.129e-161	517.0	COG0626@1|root,COG0626@2|Bacteria,1ZT9F@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Cys/Met metabolism PLP-dependent enzyme	-	-	4.4.1.1	ko:K01758	ko00260,ko00270,ko00450,ko01100,ko01130,ko01230,map00260,map00270,map00450,map01100,map01130,map01230	M00338	R00782,R01001,R02408,R04770,R04930,R09366	RC00056,RC00069,RC00348,RC00382,RC00710,RC01209,RC01210,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
WZS1_k127_7157086_1	379066.GAU_1534	2.615e-33	135.0	COG0340@1|root,COG0340@2|Bacteria,1ZTQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_LplA_LipB
WZS1_k127_7157086_4	643648.Slip_1057	1.422e-27	124.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1V9ZW@1239|Firmicutes,25AZU@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	spr	-	-	ko:K19224,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60,SH3_3
WZS1_k127_7157086_3	861299.J421_3163	3.549e-29	119.0	COG0234@1|root,COG0234@2|Bacteria,1ZTZB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WZS1_k127_7157086_0	1379270.AUXF01000005_gene790	3.665e-284	879.0	COG0459@1|root,COG0459@2|Bacteria,1ZTC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WZS1_k127_7157086_5	379066.GAU_3920	3.226e-25	119.0	COG3291@1|root,COG4932@1|root,COG3291@2|Bacteria,COG4932@2|Bacteria,1ZTYD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Leishmanolysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M8
WZS1_k127_7157086_2	1382356.JQMP01000003_gene2548	2.284e-32	134.0	COG1235@1|root,COG1235@2|Bacteria,2G711@200795|Chloroflexi,27YCU@189775|Thermomicrobia	189775|Thermomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WZS1_k127_7173005_7	1192034.CAP_3937	0.0005712	47.0	COG1213@1|root,COG1213@2|Bacteria,1RKR2@1224|Proteobacteria	1224|Proteobacteria	M	MobA-like NTP transferase domain	-	-	2.7.7.74	ko:K07281	ko00562,map00562	-	R09669	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WZS1_k127_7173005_5	944480.ATUV01000002_gene132	1.462e-17	95.0	COG0558@1|root,COG1213@1|root,COG0558@2|Bacteria,COG1213@2|Bacteria,1NN43@1224|Proteobacteria,432HN@68525|delta/epsilon subdivisions,2WYCV@28221|Deltaproteobacteria,2M7MC@213113|Desulfurellales	28221|Deltaproteobacteria	IM	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
WZS1_k127_7173005_3	379066.GAU_1047	1.244e-33	147.0	2A0JD@1|root,30NPJ@2|Bacteria,1ZUVV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WZS1_k127_7173005_4	279238.Saro_0099	7.245e-24	113.0	COG0558@1|root,COG0558@2|Bacteria,1RFEY@1224|Proteobacteria,2U90F@28211|Alphaproteobacteria,2K4ZZ@204457|Sphingomonadales	204457|Sphingomonadales	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
WZS1_k127_7173005_2	861299.J421_1752	1.093e-39	161.0	2DWGD@1|root,3407S@2|Bacteria,1ZV24@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
WZS1_k127_7173005_1	379066.GAU_2910	8.434e-49	182.0	COG3544@1|root,COG3544@2|Bacteria,1ZTVJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
WZS1_k127_7173005_0	379066.GAU_2911	9.155e-221	718.0	COG5276@1|root,COG5276@2|Bacteria,1ZSZX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7173005_6	379066.GAU_0510	9.651e-08	59.0	2DW4B@1|root,33YGG@2|Bacteria,1ZV12@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7205721_4	861299.J421_3218	5.181e-82	282.0	COG4775@1|root,COG4775@2|Bacteria,1ZT6B@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
WZS1_k127_7205721_6	1379270.AUXF01000006_gene302	2.97e-14	80.0	COG2825@1|root,COG2825@2|Bacteria,1ZU5E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
WZS1_k127_7205721_2	861299.J421_3220	3.701e-96	327.0	COG1044@1|root,COG1044@2|Bacteria,1ZSRF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
WZS1_k127_7205721_0	379066.GAU_1588	1.955e-157	510.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,1ZT4Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
WZS1_k127_7205721_1	1379270.AUXF01000006_gene299	6e-110	362.0	COG1043@1|root,COG1043@2|Bacteria,1ZT7T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
WZS1_k127_7205721_3	379066.GAU_1590	1.019e-82	290.0	COG0673@1|root,COG0673@2|Bacteria,1ZTES@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WZS1_k127_7205721_5	861299.J421_3224	1.765e-77	273.0	COG0763@1|root,COG0763@2|Bacteria,1ZTAD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
WZS1_k127_725979_4	379066.GAU_3233	5.756e-43	177.0	COG2897@1|root,COG2897@2|Bacteria,1ZV5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WZS1_k127_725979_3	234267.Acid_6501	2.663e-55	214.0	COG2897@1|root,COG2897@2|Bacteria,3Y7T0@57723|Acidobacteria	57723|Acidobacteria	M	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WZS1_k127_725979_5	573065.Astex_0126	1.875e-40	154.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
WZS1_k127_725979_2	198628.Dda3937_02691	2.179e-69	247.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,2JE4N@204037|Dickeya	1236|Gammaproteobacteria	E	Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source	-	-	3.5.99.7,4.4.1.15,4.4.1.25	ko:K01505,ko:K05396,ko:K17950	ko00270,map00270	-	R00997,R01874,R07634	RC00382,RC00419,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
WZS1_k127_725979_0	234267.Acid_5979	2.327e-196	637.0	COG2366@1|root,COG2366@2|Bacteria,3Y2PX@57723|Acidobacteria	2|Bacteria	S	PFAM peptidase S45 penicillin amidase	penA	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WZS1_k127_725979_7	379066.GAU_2437	5.195e-07	59.0	294MB@1|root,2ZS0S@2|Bacteria,1ZU7M@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_725979_1	1121451.DESAM_20172	9.719e-143	469.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,2M8GG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Sodium sulphate symporter	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
WZS1_k127_725979_6	485913.Krac_2320	1.185e-39	154.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WZS1_k127_7270453_3	861299.J421_3188	6.711e-26	107.0	COG0532@1|root,COG0532@2|Bacteria,1ZT5H@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WZS1_k127_7270453_4	696281.Desru_1900	2.986e-20	95.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,262H0@186807|Peptococcaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WZS1_k127_7270453_2	1128421.JAGA01000003_gene3155	3.813e-60	219.0	COG0130@1|root,COG0130@2|Bacteria,2NP9J@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
WZS1_k127_7270453_0	861299.J421_3191	1.533e-87	302.0	COG0196@1|root,COG0196@2|Bacteria,1ZSM5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WZS1_k127_7270453_1	861299.J421_3192	2.071e-71	255.0	COG0342@1|root,COG0342@2|Bacteria,1ZTBW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WZS1_k127_7277971_1	1121405.dsmv_0956	3.607e-68	243.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions,2WPJU@28221|Deltaproteobacteria,2MKU8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
WZS1_k127_7277971_0	316067.Geob_0363	6.907e-165	533.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria	1224|Proteobacteria	E	PFAM Peptidase S10, serine carboxypeptidase	MA20_31445	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
WZS1_k127_7279565_3	1379270.AUXF01000007_gene1013	5.343e-13	73.0	COG0708@1|root,COG1404@1|root,COG0708@2|Bacteria,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.24.3	ko:K01387,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	-	-	-	Autotransporter,Exo_endo_phos,He_PIG,Peptidase_S8
WZS1_k127_7279565_2	1379270.AUXF01000001_gene2436	1.113e-41	172.0	COG1595@1|root,COG1595@2|Bacteria,1ZV2D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
WZS1_k127_7279565_0	1089550.ATTH01000001_gene1831	4.038e-133	466.0	COG0515@1|root,COG0515@2|Bacteria,4NPN9@976|Bacteroidetes,1FJI6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NERD,Pkinase,TPR_12,TPR_8
WZS1_k127_7279565_1	502025.Hoch_4956	4.267e-68	240.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2YU7R@29|Myxococcales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WZS1_k127_7290019_0	861299.J421_4121	2.559e-269	842.0	COG5276@1|root,COG5276@2|Bacteria,1ZTC3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
WZS1_k127_7290019_1	861299.J421_4120	2.939e-63	226.0	COG3544@1|root,COG3544@2|Bacteria,1ZTPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
WZS1_k127_7290019_2	1210884.HG799465_gene11339	3.327e-29	127.0	COG0262@1|root,COG0262@2|Bacteria,2J1IB@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
WZS1_k127_7300527_0	1121920.AUAU01000005_gene959	1.687e-23	113.0	2E0D8@1|root,32W02@2|Bacteria,3Y5V4@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7300527_1	1380390.JIAT01000013_gene213	0.0001194	53.0	COG3325@1|root,COG3325@2|Bacteria,2IGIW@201174|Actinobacteria,4CPKA@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7308124_1	290397.Adeh_1044	5.641e-159	512.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2YU10@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WZS1_k127_7308124_0	861299.J421_2591	4.115e-228	726.0	COG5009@1|root,COG5009@2|Bacteria,1ZT3R@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WZS1_k127_7308124_3	861299.J421_2593	8.048e-75	268.0	COG0402@1|root,COG0402@2|Bacteria,1ZSMH@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WZS1_k127_7308124_2	1379270.AUXF01000004_gene3235	2.213e-85	287.0	COG1403@1|root,COG1403@2|Bacteria,1ZTF1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
WZS1_k127_7341620_3	1173028.ANKO01000199_gene3575	7.932e-20	104.0	COG2199@1|root,COG3614@1|root,COG3614@2|Bacteria,COG3706@2|Bacteria,1G3FB@1117|Cyanobacteria,1H736@1150|Oscillatoriales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HisKA_7TM,PAS_4,PAS_8
WZS1_k127_7341620_1	56107.Cylst_1369	2.209e-43	179.0	COG0517@1|root,COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG5002@1|root,COG0517@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1HKH1@1161|Nostocales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
WZS1_k127_7341620_2	861299.J421_4416	1.316e-24	106.0	COG2261@1|root,COG2261@2|Bacteria,1ZV7V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WZS1_k127_7341620_0	1379270.AUXF01000002_gene1214	2.434e-64	228.0	COG2885@1|root,COG2885@2|Bacteria,1ZUV2@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
WZS1_k127_7341620_5	742766.HMPREF9455_00931	1.929e-06	56.0	COG3637@1|root,COG3637@2|Bacteria,4NXWX@976|Bacteroidetes,2FRFV@200643|Bacteroidia,22YTA@171551|Porphyromonadaceae	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
WZS1_k127_7341620_4	631454.N177_3412	1.466e-14	81.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TVPN@28211|Alphaproteobacteria,1JN6Q@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS1_k127_7342308_0	945713.IALB_1306	1.605e-125	417.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
WZS1_k127_7342308_1	502025.Hoch_3578	5.231e-27	126.0	COG3005@1|root,COG3005@2|Bacteria,1QX4N@1224|Proteobacteria,43BXD@68525|delta/epsilon subdivisions,2X786@28221|Deltaproteobacteria,2Z3DX@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
WZS1_k127_7344257_3	861299.J421_5836	7.559e-114	400.0	COG0515@1|root,COG0515@2|Bacteria	861299.J421_5836|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
WZS1_k127_7344257_1	861299.J421_5759	4.526e-165	546.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,1ZUKV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS1_k127_7344257_4	1313172.YM304_17810	2.958e-83	289.0	COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CNHH@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS
WZS1_k127_7344257_11	1157708.KB907450_gene6268	1.26e-11	67.0	2EGHT@1|root,33A9W@2|Bacteria,1NHZD@1224|Proteobacteria,2VXKV@28216|Betaproteobacteria,4AG19@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7344257_8	292459.STH2001	3.964e-22	103.0	COG4467@1|root,COG4467@2|Bacteria	2|Bacteria	L	Involved in initiation control of chromosome replication	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66
WZS1_k127_7344257_6	1379270.AUXF01000007_gene978	1.503e-38	159.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS1_k127_7344257_12	616991.JPOO01000003_gene109	2.313e-06	60.0	2CK2Q@1|root,303GN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7344257_9	240015.ACP_0485	1.077e-19	104.0	COG0526@1|root,COG0526@2|Bacteria,3Y4K8@57723|Acidobacteria,2JJAP@204432|Acidobacteriia	204432|Acidobacteriia	CO	Glutathione peroxidase	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
WZS1_k127_7344257_5	1328313.DS2_19056	5.654e-43	164.0	COG1225@1|root,COG1225@2|Bacteria,1NFDB@1224|Proteobacteria,1SG07@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WZS1_k127_7344257_7	1379270.AUXF01000007_gene972	5.819e-34	133.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
WZS1_k127_7344257_13	675635.Psed_2143	2.3e-05	51.0	COG1225@1|root,COG1225@2|Bacteria,2GKME@201174|Actinobacteria,4E2X5@85010|Pseudonocardiales	201174|Actinobacteria	O	PFAM AhpC TSA family	ahpE	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
WZS1_k127_7344257_2	330214.NIDE0014	1.689e-140	477.0	COG0655@1|root,COG2146@1|root,COG0655@2|Bacteria,COG2146@2|Bacteria	2|Bacteria	P	nitrite reductase [NAD(P)H] activity	-	-	1.2.3.3,1.6.5.2,1.7.1.15	ko:K00158,ko:K00363,ko:K03809,ko:K05710	ko00130,ko00360,ko00620,ko00910,ko01100,ko01110,ko01120,ko01220,map00130,map00360,map00620,map00910,map01100,map01110,map01120,map01220	M00530,M00545	R00207,R00787,R02964,R03643,R03816,R06782,R06783	RC00098,RC00176,RC00819,RC02745	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_red,Rieske,TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WZS1_k127_7344257_0	1121920.AUAU01000013_gene1695	1.698e-288	908.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,3Y2WK@57723|Acidobacteria	57723|Acidobacteria	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1
WZS1_k127_735475_1	502025.Hoch_1931	2.017e-96	335.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
WZS1_k127_735475_0	1121930.AQXG01000001_gene1531	2.309e-202	652.0	COG2211@1|root,COG2211@2|Bacteria,4NE3F@976|Bacteroidetes,1IPIA@117747|Sphingobacteriia	976|Bacteroidetes	G	Major Facilitator	-	-	-	ko:K16211	-	-	-	-	ko00000,ko02000	2.A.2.6	-	-	MFS_1
WZS1_k127_7406070_0	861299.J421_2948	2.584e-245	796.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1ZSUS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	MU	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
WZS1_k127_7406070_1	886293.Sinac_4949	1.935e-14	74.0	COG0799@1|root,COG0799@2|Bacteria,2J0AM@203682|Planctomycetes	203682|Planctomycetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WZS1_k127_7409532_1	861299.J421_3630	2.722e-134	457.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
WZS1_k127_7409532_3	861299.J421_3631	5.336e-30	128.0	COG2010@1|root,COG2010@2|Bacteria,1ZTKA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
WZS1_k127_7409532_2	861299.J421_3635	6.294e-51	205.0	COG0565@1|root,COG0565@2|Bacteria,1ZT19@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	SpoU rRNA Methylase family	-	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WZS1_k127_7409532_0	861299.J421_3743	2.366e-162	526.0	COG2805@1|root,COG2805@2|Bacteria,1ZSTM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS1_k127_7444637_1	379066.GAU_0583	3.769e-105	344.0	COG0677@1|root,COG0677@2|Bacteria,1ZT42@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	UDP binding domain	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WZS1_k127_7444637_0	861299.J421_0144	7.081e-177	565.0	COG1004@1|root,COG1004@2|Bacteria,1ZTH3@142182|Gemmatimonadetes	2|Bacteria	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WZS1_k127_7444637_2	861299.J421_0145	2.566e-43	160.0	COG0451@1|root,COG0451@2|Bacteria,1ZUJJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WZS1_k127_7473591_5	861299.J421_3238	1.652e-39	164.0	COG0789@1|root,COG0789@2|Bacteria,1ZTSI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
WZS1_k127_7473591_3	243231.GSU0006	5.231e-71	244.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WZS1_k127_7473591_6	243231.GSU0006	2.211e-29	128.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WZS1_k127_7473591_4	1307761.L21SP2_3279	3.404e-41	167.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K03977,ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko03009	-	-	-	G3P_acyltransf
WZS1_k127_7473591_1	562970.Btus_1769	5.666e-136	446.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WZS1_k127_7473591_0	379066.GAU_1600	3.889e-147	477.0	COG1625@1|root,COG1625@2|Bacteria,1ZSQ7@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
WZS1_k127_7473591_2	1379270.AUXF01000004_gene2897	5.134e-90	304.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
WZS1_k127_7475748_0	644966.Tmar_1686	0.0	1199.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WZS1_k127_7476775_1	1050201.KB913034_gene185	4.082e-11	73.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,3VQPB@526524|Erysipelotrichia	526524|Erysipelotrichia	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WZS1_k127_7476775_0	246194.CHY_2385	3.134e-222	701.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,42FHK@68295|Thermoanaerobacterales	186801|Clostridia	F	PFAM formate-tetrahydrofolate ligase FTHFS	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WZS1_k127_7487062_6	861299.J421_2978	1.395e-05	55.0	COG1729@1|root,COG1729@2|Bacteria,1ZTBJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	-
WZS1_k127_7487062_1	1379270.AUXF01000005_gene568	3.559e-157	507.0	2CD20@1|root,2Z7SQ@2|Bacteria,1ZTFE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7487062_0	861299.J421_2981	2.656e-271	880.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1ZT1S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2,RadC
WZS1_k127_7487062_3	926569.ANT_13710	5.356e-77	270.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
WZS1_k127_7487062_2	379066.GAU_2121	1.463e-128	423.0	COG0436@1|root,COG0436@2|Bacteria,1ZTCU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS1_k127_7487062_5	861299.J421_2984	2.158e-08	65.0	2FFNT@1|root,347K5@2|Bacteria,1ZTY9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7491740_0	861299.J421_3324	1.311e-64	224.0	COG0260@1|root,COG0260@2|Bacteria,1ZSPX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WZS1_k127_7491740_1	861299.J421_3323	1.686e-06	61.0	COG4206@1|root,COG4206@2|Bacteria,1ZT1E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug
WZS1_k127_7506468_0	477974.Daud_1473	3.025e-286	906.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25ZYN@186807|Peptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WZS1_k127_7506468_1	1379270.AUXF01000005_gene588	2.305e-47	189.0	COG2372@1|root,COG2372@2|Bacteria,1ZTUI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Bacterial Ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5
WZS1_k127_7513751_0	290397.Adeh_0846	1.077e-93	312.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
WZS1_k127_7513751_3	857087.Metme_1231	2.201e-41	167.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1XF3J@135618|Methylococcales	135618|Methylococcales	C	TIGRFAM SUF system FeS	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WZS1_k127_7513751_1	861299.J421_2070	1.8e-45	171.0	28NYH@1|root,2ZBVN@2|Bacteria,1ZTSS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Disulphide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
WZS1_k127_7513751_4	886293.Sinac_1864	7.815e-36	156.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WZS1_k127_7513751_2	886293.Sinac_1864	5.858e-45	189.0	COG2246@1|root,COG2246@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WZS1_k127_7518791_0	518766.Rmar_0272	7.665e-207	660.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,1FJXZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	EU	Prolyl oligopeptidase family	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
WZS1_k127_7518791_4	1157637.KB892091_gene5791	2.064e-09	69.0	2E69S@1|root,330XP@2|Bacteria,2I7R6@201174|Actinobacteria	201174|Actinobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
WZS1_k127_7518791_2	1379270.AUXF01000004_gene2933	3.594e-41	162.0	COG2755@1|root,COG2755@2|Bacteria,1ZU6K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7518791_1	761193.Runsl_1338	1.461e-42	161.0	COG0346@1|root,COG0346@2|Bacteria,4NGE0@976|Bacteroidetes,47KJP@768503|Cytophagia	976|Bacteroidetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
WZS1_k127_7529670_3	861299.J421_3529	1.068e-46	178.0	COG0584@1|root,COG0584@2|Bacteria,1ZTMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WZS1_k127_7529670_0	1144275.COCOR_02843	5.691e-187	604.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YVB7@29|Myxococcales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS1_k127_7529670_1	1111479.AXAR01000006_gene748	2.644e-122	404.0	COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli	91061|Bacilli	F	Pantothenic acid kinase	coaA	GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.33	ko:K00867	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
WZS1_k127_7529670_4	290397.Adeh_2288	1.536e-05	55.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4440,SnoaL_2,SnoaL_3
WZS1_k127_7529670_2	1379270.AUXF01000003_gene3585	1.608e-78	273.0	COG3653@1|root,COG3653@2|Bacteria,1ZUQ6@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_7600973_5	502025.Hoch_5309	5.289e-54	192.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
WZS1_k127_7600973_3	861299.J421_2866	2.001e-120	400.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
WZS1_k127_7600973_8	1379270.AUXF01000001_gene2766	1.308e-07	60.0	COG1225@1|root,COG1225@2|Bacteria,1ZUGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WZS1_k127_7600973_7	379066.GAU_2624	1.819e-24	106.0	COG1225@1|root,COG1225@2|Bacteria,1ZUGC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WZS1_k127_7600973_0	1379270.AUXF01000005_gene637	3.195e-171	549.0	COG0498@1|root,COG0498@2|Bacteria,1ZSVV@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS1_k127_7600973_4	248742.XP_005651548.1	2.709e-58	215.0	COG0083@1|root,KOG1537@2759|Eukaryota,37JTN@33090|Viridiplantae,34IEI@3041|Chlorophyta	3041|Chlorophyta	E	homoserine kinase	-	-	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iRC1080.CRv4_Au5_s2_g8449_t1	GHMP_kinases_C,GHMP_kinases_N
WZS1_k127_7600973_2	861299.J421_0516	2.58e-133	435.0	COG3288@1|root,COG3288@2|Bacteria,1ZUJQ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WZS1_k127_7600973_6	1177181.T9A_00261	5.056e-28	115.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,1S9UK@1236|Gammaproteobacteria,1XM5U@135619|Oceanospirillales	135619|Oceanospirillales	C	COG3288 NAD NADP transhydrogenase alpha subunit	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
WZS1_k127_7600973_1	1173021.ALWA01000038_gene1736	2.13e-161	526.0	COG1282@1|root,COG1282@2|Bacteria,1G2AX@1117|Cyanobacteria	1117|Cyanobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
WZS1_k127_7620871_1	861299.J421_0558	7.231e-55	204.0	COG0793@1|root,COG0793@2|Bacteria,1ZV0G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	N-terminal domain of Peptidase_S41 in eukaryotic IRBP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41,Peptidase_S41_N
WZS1_k127_7620871_3	861299.J421_5853	3.142e-32	127.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WZS1_k127_7620871_2	861299.J421_5854	1.499e-34	135.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WZS1_k127_7620871_0	861299.J421_1682	1.217e-55	216.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1ZTSR@142182|Gemmatimonadetes	2|Bacteria	T	Bacterial transcriptional activator domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
WZS1_k127_7622756_3	1379270.AUXF01000006_gene146	3.185e-111	373.0	COG0534@1|root,COG0534@2|Bacteria,1ZUAU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WZS1_k127_7622756_2	861299.J421_1944	2.293e-118	394.0	COG0659@1|root,COG0659@2|Bacteria,1ZTYW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Sulfate_transp
WZS1_k127_7622756_4	1122605.KB893643_gene502	1.186e-51	186.0	COG0659@1|root,COG0659@2|Bacteria,4NF1C@976|Bacteroidetes,1ISE6@117747|Sphingobacteriia	976|Bacteroidetes	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WZS1_k127_7622756_1	861299.J421_3703	1.291e-168	554.0	COG3185@1|root,COG3185@2|Bacteria,1ZT62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal	-	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
WZS1_k127_7622756_0	379066.GAU_2122	3.992e-194	631.0	COG3508@1|root,COG3508@2|Bacteria,1ZTFN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	Q	homogentisate 1,2-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
WZS1_k127_7622756_6	445335.CBN_A0062	9.955e-13	72.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7622756_5	1122244.AUGF01000070_gene953	4.887e-17	81.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,1SDC6@1236|Gammaproteobacteria,3NRXM@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_7657735_6	1134413.ANNK01000092_gene181	0.0004857	43.0	COG2050@1|root,COG2050@2|Bacteria,1VA0Y@1239|Firmicutes,4IR16@91061|Bacilli,1ZRQG@1386|Bacillus	91061|Bacilli	Q	Thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
WZS1_k127_7657735_0	518766.Rmar_1549	9.649e-305	949.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FIUV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	dehydrogenase, E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WZS1_k127_7657735_2	1410620.SHLA_10c001170	9.02e-108	380.0	COG0508@1|root,COG0508@2|Bacteria,1R0J5@1224|Proteobacteria,2U28K@28211|Alphaproteobacteria,4BATY@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WZS1_k127_7657735_5	1131813.AQVT01000001_gene2403	3.789e-45	178.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2TRRN@28211|Alphaproteobacteria,1JURW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
WZS1_k127_7657735_1	1095769.CAHF01000017_gene18	2.503e-109	370.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,2VZMU@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WZS1_k127_7657735_3	316055.RPE_3198	4.135e-73	256.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,2U2YW@28211|Alphaproteobacteria,3JYK9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
WZS1_k127_7657735_4	573370.DMR_18150	3.724e-70	243.0	COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,42NJF@68525|delta/epsilon subdivisions,2WMJC@28221|Deltaproteobacteria,2MCCX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WZS1_k127_7673734_1	861299.J421_2732	1.971e-87	296.0	COG1024@1|root,COG1024@2|Bacteria,1ZT76@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
WZS1_k127_7673734_2	379066.GAU_0815	9.175e-73	258.0	COG1195@1|root,COG1195@2|Bacteria,1ZSRU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WZS1_k127_7673734_3	479433.Caci_0005	4.895e-07	55.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria	201174|Actinobacteria	S	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
WZS1_k127_7673734_0	243231.GSU0003	3.48e-230	724.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,43U22@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WZS1_k127_77447_6	861299.J421_2949	2.289e-28	121.0	COG0799@1|root,COG0799@2|Bacteria,1ZU0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WZS1_k127_77447_2	1121406.JAEX01000007_gene2385	1.44e-93	330.0	COG1461@1|root,COG1461@2|Bacteria,1NKAM@1224|Proteobacteria,42U2G@68525|delta/epsilon subdivisions,2WQBG@28221|Deltaproteobacteria,2M8TG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Dihydroxyacetone kinase family	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
WZS1_k127_77447_4	880073.Calab_2408	4.053e-38	152.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WZS1_k127_77447_9	861299.J421_2951	3.687e-06	59.0	2F1RZ@1|root,33US3@2|Bacteria,1ZUSC@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
WZS1_k127_77447_8	861299.J421_2952	4.936e-24	102.0	COG0238@1|root,COG0238@2|Bacteria,1ZU47@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WZS1_k127_77447_7	861299.J421_2953	1.194e-27	115.0	COG0360@1|root,COG0360@2|Bacteria,1ZTYY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WZS1_k127_77447_3	1382304.JNIL01000001_gene3078	1.667e-55	201.0	COG2258@1|root,COG2258@2|Bacteria,1UB2C@1239|Firmicutes,4HB26@91061|Bacilli	91061|Bacilli	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
WZS1_k127_77447_0	997346.HMPREF9374_2493	7.287e-132	435.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,27BBQ@186824|Thermoactinomycetaceae	91061|Bacilli	J	Protein of unknown function (DUF933)	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WZS1_k127_77447_5	1489678.RDMS_05025	1.088e-28	119.0	2DNS7@1|root,32YWC@2|Bacteria,1WKTD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
WZS1_k127_77447_1	378806.STAUR_7585	7.243e-109	355.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
WZS1_k127_801084_1	379066.GAU_3769	1.326e-153	496.0	COG2355@1|root,COG2355@2|Bacteria,1ZT5A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WZS1_k127_801084_3	1265313.HRUBRA_01064	2.478e-64	239.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	steT	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
WZS1_k127_801084_2	56110.Oscil6304_1572	1.582e-148	513.0	COG2936@1|root,COG2936@2|Bacteria	2|Bacteria	V	dipeptidyl-peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
WZS1_k127_801084_0	483219.LILAB_14600	1.341e-178	575.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42NT5@68525|delta/epsilon subdivisions,2WIWR@28221|Deltaproteobacteria,2YU3S@29|Myxococcales	28221|Deltaproteobacteria	IQ	Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	alkK	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WZS1_k127_801084_4	285514.JNWO01000001_gene4182	2.475e-42	160.0	COG2124@1|root,COG2124@2|Bacteria,2IBKI@201174|Actinobacteria	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WZS1_k127_803954_3	215803.DB30_0411	1.602e-26	118.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria,2YWK1@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS1_k127_803954_1	504728.K649_07895	2.167e-103	347.0	COG1171@1|root,COG1171@2|Bacteria,1WJZG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS1_k127_803954_0	471854.Dfer_2714	6.263e-163	525.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47JXE@768503|Cytophagia	976|Bacteroidetes	S	PFAM Peptidase family M20 M25 M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_803954_2	247639.MGP2080_08314	1.981e-41	174.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RPIW@1236|Gammaproteobacteria,1JA3P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
WZS1_k127_813496_3	1217720.ALOX01000082_gene1460	2.455e-59	220.0	COG0210@1|root,COG0210@2|Bacteria,1R8C5@1224|Proteobacteria,2U0BZ@28211|Alphaproteobacteria,2JZQ4@204441|Rhodospirillales	204441|Rhodospirillales	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WZS1_k127_813496_0	316067.Geob_1840	3.33e-72	267.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria,43U6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
WZS1_k127_813496_4	243365.CV_3208	1.485e-52	192.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,2VPJM@28216|Betaproteobacteria,2KRKJ@206351|Neisseriales	206351|Neisseriales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WZS1_k127_813496_5	1270196.JCKI01000002_gene301	2.045e-06	58.0	COG3637@1|root,COG3637@2|Bacteria,4NVY6@976|Bacteroidetes	976|Bacteroidetes	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_2
WZS1_k127_813496_2	861299.J421_3685	1.611e-66	232.0	COG0231@1|root,COG0231@2|Bacteria,1ZT2N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WZS1_k127_813496_1	867845.KI911784_gene3726	1.185e-68	242.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,3756Y@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WZS1_k127_826905_2	1173022.Cri9333_3045	2.306e-64	226.0	COG1304@1|root,COG1304@2|Bacteria,1G32Y@1117|Cyanobacteria,1HA70@1150|Oscillatoriales	1117|Cyanobacteria	C	COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid	lldD	-	1.1.2.3,1.1.3.46	ko:K00101,ko:K16422	ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130	-	R00196,R06633	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
WZS1_k127_826905_1	861299.J421_2056	3.689e-111	369.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WZS1_k127_826905_0	1382359.JIAL01000001_gene2689	2.282e-181	578.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3NT@57723|Acidobacteria,2JIBK@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,PD40,Peptidase_S9
WZS1_k127_841313_1	1297865.APJD01000030_gene1680	2.772e-63	230.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRFP@28211|Alphaproteobacteria,3K0MF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Beta-lactamase	dap	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Beta-lactamase,DAP_B
WZS1_k127_841313_0	861299.J421_6092	1.054e-167	540.0	COG1680@1|root,COG1680@2|Bacteria,1ZUKR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	Domain of unknown function (DUF3471)	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
WZS1_k127_841313_2	745411.B3C1_00785	2.85e-47	177.0	28PFD@1|root,2ZC6I@2|Bacteria,1R8PT@1224|Proteobacteria,1S2BA@1236|Gammaproteobacteria,1JAXR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	VP2004	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_841313_3	450851.PHZ_c1900	1.372e-31	126.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,2KF9E@204458|Caulobacterales	204458|Caulobacterales	L	ATP-dependent helicase	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
WZS1_k127_88212_0	880073.Calab_0069	6.457e-166	530.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acdA	-	1.3.8.1,1.3.99.12	ko:K00248,ko:K09478	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS1_k127_88212_1	1218075.BAYA01000012_gene3548	1.619e-05	56.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
WZS1_k127_882164_2	861299.J421_3097	2.051e-41	171.0	2EYUI@1|root,33S1Q@2|Bacteria,1ZTHR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_882164_4	379066.GAU_1452	7.904e-15	87.0	2F0K0@1|root,33TNP@2|Bacteria,1ZTJU@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_882164_3	1210884.HG799466_gene12319	1.252e-35	142.0	COG0295@1|root,COG0295@2|Bacteria,2J0JM@203682|Planctomycetes	203682|Planctomycetes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
WZS1_k127_882164_0	861299.J421_3094	6.819e-149	480.0	COG1015@1|root,COG1015@2|Bacteria,1ZTG3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
WZS1_k127_882164_1	861299.J421_3093	1.726e-43	168.0	COG0787@1|root,COG0787@2|Bacteria,1ZT57@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WZS1_k127_913734_9	861299.J421_2636	2.093e-08	63.0	2FAWT@1|root,3433T@2|Bacteria,1ZTS1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_913734_6	861299.J421_2630	2.398e-16	93.0	COG0355@1|root,COG0355@2|Bacteria,1ZU1K@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
WZS1_k127_913734_0	861299.J421_2629	1.59e-241	755.0	COG0055@1|root,COG0055@2|Bacteria,1ZSNP@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WZS1_k127_913734_3	861299.J421_2628	4.063e-99	331.0	COG0224@1|root,COG0224@2|Bacteria,1ZSZR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WZS1_k127_913734_1	861299.J421_2627	6.704e-236	740.0	COG0056@1|root,COG0056@2|Bacteria,1ZSNY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WZS1_k127_913734_4	1379270.AUXF01000004_gene3175	4.154e-36	153.0	COG2207@1|root,COG2207@2|Bacteria,1ZUCN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WZS1_k127_913734_5	861299.J421_2626	5.131e-35	152.0	COG1051@1|root,COG1051@2|Bacteria,1ZTP5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS1_k127_913734_2	379066.GAU_0710	2.878e-131	426.0	COG0568@1|root,COG0568@2|Bacteria,1ZTCX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS1_k127_913734_8	1329250.WOSG25_100750	2.047e-08	56.0	2DRA2@1|root,33AVQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_914311_1	1094508.Tsac_2196	2.874e-93	313.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,42EPG@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WZS1_k127_914311_0	1379270.AUXF01000006_gene86	1.315e-187	623.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1ZSWJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WZS1_k127_914311_2	1379270.AUXF01000006_gene88	9.113e-14	78.0	COG3027@1|root,COG3027@2|Bacteria,1ZU4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
WZS1_k127_916191_3	234267.Acid_2720	2.472e-31	126.0	COG0624@1|root,COG0624@2|Bacteria,3Y2UM@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_916191_1	861299.J421_1756	6.599e-134	438.0	COG0624@1|root,COG0624@2|Bacteria,1ZUA4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS1_k127_916191_5	1538295.JY96_07760	2.77e-23	114.0	COG3746@1|root,COG3746@2|Bacteria,1MV8P@1224|Proteobacteria,2VNJT@28216|Betaproteobacteria,1KMYJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Putative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_5
WZS1_k127_916191_6	861299.J421_1081	7.4e-17	90.0	COG2314@1|root,COG2314@2|Bacteria	2|Bacteria	J	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
WZS1_k127_916191_0	1089550.ATTH01000001_gene237	4.205e-175	573.0	COG0308@1|root,COG0308@2|Bacteria,4NFNJ@976|Bacteroidetes	976|Bacteroidetes	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WZS1_k127_916191_4	760192.Halhy_2762	1.555e-24	119.0	COG4319@1|root,COG4319@2|Bacteria,4PP1J@976|Bacteroidetes,1J0X2@117747|Sphingobacteriia	976|Bacteroidetes	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
WZS1_k127_916191_2	1502851.FG93_03167	4.063e-33	147.0	COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,2UD6F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
WZS1_k127_966413_3	861299.J421_3552	2.584e-25	116.0	COG0810@1|root,COG0810@2|Bacteria,1ZTWX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
WZS1_k127_966413_2	379066.GAU_1944	5.864e-33	133.0	COG0848@1|root,COG0848@2|Bacteria,1ZTRS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
WZS1_k127_966413_0	861299.J421_3554	6.485e-55	201.0	COG0811@1|root,COG0811@2|Bacteria,1ZTBF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
WZS1_k127_966413_5	1242864.D187_009137	7.563e-17	93.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2YVFR@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WZS1_k127_966413_1	379066.GAU_1948	3.724e-54	196.0	COG0629@1|root,COG0629@2|Bacteria,1ZTPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WZS1_k127_966413_4	883156.HMPREF9282_01903	1.327e-21	103.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4H4P3@909932|Negativicutes	909932|Negativicutes	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WZS1_k127_966413_6	1410622.JNKY01000015_gene275	4.673e-16	89.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,27IG5@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
WZS1_k127_966413_7	1123227.KB899336_gene364	3.746e-11	66.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2UBQ9@28211|Alphaproteobacteria,2JT79@204441|Rhodospirillales	204441|Rhodospirillales	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WZS1_k127_975868_0	861299.J421_6089	1.999e-158	518.0	COG1073@1|root,COG1680@1|root,COG1073@2|Bacteria,COG1680@2|Bacteria,1ZU86@142182|Gemmatimonadetes	2|Bacteria	V	Domain of unknown function (DUF3471)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Beta-lactamase,DUF3471,Hydrolase_4
WZS1_k127_975868_1	448385.sce5490	9.132e-106	356.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter, ATP-binding protein	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WZS1_k127_975868_2	1192034.CAP_2342	1.254e-08	58.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter, ATP-binding protein	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WZS1_k127_983090_1	479434.Sthe_2389	2.71e-56	201.0	COG4122@1|root,COG4122@2|Bacteria,2G990@200795|Chloroflexi,27ZCN@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
WZS1_k127_983090_2	1121920.AUAU01000005_gene976	1.689e-31	127.0	2E31H@1|root,32Y1W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_983090_0	861299.J421_1048	4.734e-93	321.0	COG2091@1|root,COG2091@2|Bacteria	2|Bacteria	H	lysine biosynthetic process via aminoadipic acid	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
WZS1_k127_983707_0	1379270.AUXF01000004_gene3232	2.768e-152	494.0	COG2204@1|root,COG2204@2|Bacteria,1ZSW0@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
WZS1_k127_983707_1	1379270.AUXF01000004_gene3229	1.395e-84	296.0	COG5000@1|root,COG5000@2|Bacteria,1ZTBX@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WZS1_k127_983707_2	1267535.KB906767_gene2479	2.742e-78	292.0	COG0531@1|root,COG0531@2|Bacteria,3Y2T1@57723|Acidobacteria,2JI3B@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WZS1_k127_99603_5	379066.GAU_1933	4.219e-47	178.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
WZS1_k127_99603_3	1379270.AUXF01000006_gene27	1.498e-101	342.0	COG0142@1|root,COG0142@2|Bacteria,1ZT7D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
WZS1_k127_99603_9	1379270.AUXF01000006_gene28	4.27e-24	105.0	2FH8C@1|root,3492Q@2|Bacteria,1ZTXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
WZS1_k127_99603_10	379066.GAU_1930	2.922e-13	72.0	COG1826@1|root,COG1826@2|Bacteria,1ZU4N@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WZS1_k127_99603_2	861299.J421_3538	9.803e-102	354.0	COG0760@1|root,COG0760@2|Bacteria,1ZTD1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_2
WZS1_k127_99603_11	1379698.RBG1_1C00001G1748	8.262e-08	66.0	COG0457@1|root,COG0457@2|Bacteria,2NS1B@2323|unclassified Bacteria	2|Bacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS1_k127_99603_6	1121385.AQXW01000004_gene2450	4.038e-46	171.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,1ZWS1@145357|Dermacoccaceae	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II,PTS_EIIB
WZS1_k127_99603_4	861299.J421_3535	2.073e-95	325.0	COG0006@1|root,COG0006@2|Bacteria,1ZSTY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
WZS1_k127_99603_8	489653.NLA_18040	7.12e-28	121.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,2KR4E@206351|Neisseriales	206351|Neisseriales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
WZS1_k127_99603_1	1379270.AUXF01000006_gene35	8.12e-157	505.0	COG2805@1|root,COG2805@2|Bacteria,1ZU8X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS1_k127_99603_0	861299.J421_3533	1.743e-221	694.0	COG0439@1|root,COG0439@2|Bacteria,1ZT0Q@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WZS1_k127_99603_7	861299.J421_3532	3.279e-45	175.0	COG2045@1|root,COG2045@2|Bacteria,1ZTM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	2-phosphosulpholactate phosphatase	comB	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
## 2293 queries scanned
## Total time (seconds): 6.6414313316345215
## Rate: 345.26 q/s