## Tue Nov 12 05:48:16 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/WX/WZS2_bin.21.fa -m mmseqs --itype genome -o WZS2_bin.21 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/WZS2_bin.21 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WZS2_k127_10043301_1	926569.ANT_29890	4.254e-192	607.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WZS2_k127_10043301_8	926569.ANT_29880	1.007e-55	198.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WZS2_k127_10043301_11	926569.ANT_00330	5.218e-43	167.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WZS2_k127_10043301_5	926569.ANT_05520	3.791e-124	407.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WZS2_k127_10043301_3	926569.ANT_05530	6.623e-143	462.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WZS2_k127_10043301_2	926569.ANT_05540	3.362e-158	504.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WZS2_k127_10043301_13	1289387.AUKW01000006_gene3906	3.969e-06	59.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WZS2_k127_10043301_4	926569.ANT_07430	4.085e-125	414.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
WZS2_k127_10043301_10	649638.Trad_2282	8.574e-44	178.0	COG1653@1|root,COG1653@2|Bacteria,1WIUT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027,ko:K05813	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	SBP_bac_8
WZS2_k127_10043301_6	926569.ANT_00990	4.784e-90	302.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WZS2_k127_10043301_9	349741.Amuc_0554	5.73e-48	183.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,2IU98@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Ribonuclease HII	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WZS2_k127_10043301_0	765420.OSCT_1972	4.677e-200	641.0	COG1506@1|root,COG1506@2|Bacteria,2GAHG@200795|Chloroflexi,377JQ@32061|Chloroflexia	32061|Chloroflexia	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WZS2_k127_10043301_7	926569.ANT_15450	9.888e-68	236.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WZS2_k127_10087189_2	926569.ANT_11390	1.392e-83	282.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WZS2_k127_10087189_0	926569.ANT_11400	4.867e-195	639.0	COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
WZS2_k127_10087189_3	926569.ANT_13170	2.09e-59	218.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10087189_4	926569.ANT_21000	8.635e-51	184.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
WZS2_k127_10087189_1	1089548.KI783301_gene319	2.046e-87	292.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,3WE0H@539002|Bacillales incertae sedis	91061|Bacilli	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WZS2_k127_10087189_5	1304874.JAFY01000005_gene1612	6.579e-24	105.0	COG0697@1|root,COG0697@2|Bacteria,3TAVN@508458|Synergistetes	508458|Synergistetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS2_k127_10196643_1	357808.RoseRS_2450	3.548e-158	514.0	COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi,376ZJ@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS2_k127_10196643_2	56780.SYN_02739	1.167e-124	406.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42UAF@68525|delta/epsilon subdivisions,2WQGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
WZS2_k127_10196643_5	56780.SYN_02280	8.39e-20	96.0	COG1714@1|root,COG1714@2|Bacteria,1MZAD@1224|Proteobacteria,43B7B@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
WZS2_k127_10196643_4	383372.Rcas_1195	1.293e-25	111.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
WZS2_k127_10196643_6	426716.JOAJ01000001_gene1082	1.125e-07	60.0	COG1366@1|root,COG1366@2|Bacteria,2HI53@201174|Actinobacteria,4G2TH@85025|Nocardiaceae	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS,STAS_2
WZS2_k127_10196643_0	326427.Cagg_2274	1.841e-223	709.0	COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,2G64W@200795|Chloroflexi,376VC@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase
WZS2_k127_10196643_3	316274.Haur_3570	1.006e-27	115.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,2GAB0@200795|Chloroflexi,374U6@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD
WZS2_k127_10212943_8	1041930.Mtc_1942	1.756e-39	160.0	COG0477@1|root,arCOG00132@2157|Archaea,2XW9U@28890|Euryarchaeota	28890|Euryarchaeota	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
WZS2_k127_10212943_3	485913.Krac_5632	3.39e-73	256.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi	200795|Chloroflexi	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WZS2_k127_10212943_4	926569.ANT_22260	2.557e-72	248.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS2_k127_10212943_0	926569.ANT_25700	0.0	1115.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
WZS2_k127_10212943_7	926569.ANT_25690	1.442e-46	183.0	COG3287@1|root,COG3287@2|Bacteria,2G7G0@200795|Chloroflexi	200795|Chloroflexi	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
WZS2_k127_10212943_12	1121931.AUHG01000010_gene237	1.878e-10	71.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,1HY8G@117743|Flavobacteriia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WZS2_k127_10212943_6	926560.KE387027_gene334	6.548e-47	174.0	COG0262@1|root,COG0262@2|Bacteria,1WMN7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
WZS2_k127_10212943_1	243365.CV_1027	2.271e-133	428.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,2KPIK@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
WZS2_k127_10212943_2	926561.KB900622_gene464	5.143e-109	360.0	COG0524@1|root,COG0524@2|Bacteria,1V0D5@1239|Firmicutes,249XQ@186801|Clostridia	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WZS2_k127_10212943_9	1347368.HG964403_gene4776	1.798e-31	130.0	COG4122@1|root,COG4122@2|Bacteria,1TYQB@1239|Firmicutes,4I7V4@91061|Bacilli,1ZE8N@1386|Bacillus	91061|Bacilli	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
WZS2_k127_10212943_5	926560.KE387025_gene4063	8.018e-65	228.0	COG0317@1|root,COG0317@2|Bacteria,1WMN8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
WZS2_k127_10212943_14	479433.Caci_7358	8.958e-06	57.0	COG0824@1|root,COG0824@2|Bacteria,2IFAK@201174|Actinobacteria	201174|Actinobacteria	S	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
WZS2_k127_10212943_11	519989.ECTPHS_07636	1.021e-15	87.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1SAHQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
WZS2_k127_10212943_10	926550.CLDAP_32540	1.343e-27	119.0	COG1765@1|root,COG1765@2|Bacteria,2G978@200795|Chloroflexi	200795|Chloroflexi	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WZS2_k127_10212943_13	1232410.KI421421_gene3299	1.449e-07	55.0	COG2514@1|root,COG2514@2|Bacteria	2|Bacteria	S	catechol 2,3-dioxygenase activity	-	-	1.13.11.2	ko:K00446,ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
WZS2_k127_10228304_9	322710.Avin_28000	9.213e-06	52.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,1RMSH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG0366 Glycosidases	treS	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
WZS2_k127_10228304_1	926550.CLDAP_37990	4.055e-270	845.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
WZS2_k127_10228304_3	1382356.JQMP01000003_gene2462	5.39e-61	216.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi,27Y2Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
WZS2_k127_10228304_7	1144275.COCOR_00104	9.566e-36	139.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS2_k127_10228304_8	502025.Hoch_2300	1.308e-28	118.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS2_k127_10228304_6	118173.KB235914_gene842	6.637e-47	194.0	COG1262@1|root,COG1672@1|root,COG4249@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,COG4249@2|Bacteria,1G0ZT@1117|Cyanobacteria,1H92Y@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14,TIR_2
WZS2_k127_10228304_2	926550.CLDAP_29080	4.501e-191	624.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
WZS2_k127_10228304_5	247490.KSU1_D0853	1.241e-50	203.0	COG5001@1|root,COG5001@2|Bacteria,2IY4F@203682|Planctomycetes	203682|Planctomycetes	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
WZS2_k127_10228304_0	383372.Rcas_1300	0.0	1177.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
WZS2_k127_10228304_4	1173029.JH980292_gene1866	6.388e-56	199.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1H8QW@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
WZS2_k127_10265043_5	1210884.HG799463_gene10153	3.152e-10	63.0	COG1788@1|root,COG1788@2|Bacteria	2|Bacteria	I	CoA-transferase activity	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS2_k127_10265043_1	1125863.JAFN01000001_gene1123	1.159e-88	311.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
WZS2_k127_10265043_2	1408254.T458_04785	1.744e-82	284.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H9TV@91061|Bacilli,26RBP@186822|Paenibacillaceae	91061|Bacilli	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
WZS2_k127_10265043_4	926561.KB900618_gene373	3.013e-48	183.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3WB33@53433|Halanaerobiales	186801|Clostridia	H	Belongs to the precorrin methyltransferase family	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
WZS2_k127_10265043_0	717605.Theco_2570	7.374e-130	423.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,4HBQC@91061|Bacilli,26RU4@186822|Paenibacillaceae	91061|Bacilli	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
WZS2_k127_10265043_3	1120973.AQXL01000117_gene375	8.377e-79	271.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
WZS2_k127_10320816_5	1121087.AUCK01000025_gene1827	4.067e-11	64.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli,1ZCQC@1386|Bacillus	91061|Bacilli	E	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS2_k127_10320816_4	1278073.MYSTI_00031	8.951e-17	87.0	COG0727@1|root,COG0727@2|Bacteria,1NJH8@1224|Proteobacteria,432FF@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
WZS2_k127_10320816_0	383372.Rcas_2386	4.937e-113	383.0	COG1020@1|root,COG1020@2|Bacteria,2G7PI@200795|Chloroflexi	200795|Chloroflexi	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
WZS2_k127_10320816_3	1382356.JQMP01000003_gene1897	2.128e-45	169.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
WZS2_k127_10320816_2	1382306.JNIM01000001_gene2644	1.138e-49	185.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WZS2_k127_10320816_1	926569.ANT_17350	2.121e-64	232.0	COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
WZS2_k127_10320816_7	604331.AUHY01000070_gene2236	2.465e-09	63.0	COG3375@1|root,COG3375@2|Bacteria,1WI6K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	carboxylic acid catabolic process	-	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
WZS2_k127_10339397_5	926569.ANT_16420	1.553e-23	104.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
WZS2_k127_10339397_1	926569.ANT_16410	2.024e-105	358.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
WZS2_k127_10339397_0	926569.ANT_16400	2.069e-166	539.0	2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10339397_2	926569.ANT_16390	4.496e-45	167.0	2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10339397_3	926569.ANT_18300	1.2e-30	125.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
WZS2_k127_10339397_4	926569.ANT_18310	1.935e-26	113.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS2_k127_10363218_10	1120972.AUMH01000004_gene1502	1.198e-14	75.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,278BX@186823|Alicyclobacillaceae	91061|Bacilli	T	helix_turn_helix, Lux Regulon	yhcZ	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_10363218_5	1499967.BAYZ01000080_gene935	2.993e-67	250.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
WZS2_k127_10363218_3	324602.Caur_2350	1.182e-79	281.0	COG1819@1|root,COG1819@2|Bacteria,2G865@200795|Chloroflexi,375NW@32061|Chloroflexia	32061|Chloroflexia	CG	PFAM glycosyl transferase, family 28	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
WZS2_k127_10363218_8	330084.JNYZ01000031_gene311	7.541e-20	102.0	COG0204@1|root,COG0204@2|Bacteria,2GP8A@201174|Actinobacteria,4E2V5@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WZS2_k127_10363218_6	555079.Toce_2076	1.062e-45	173.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia,42GT3@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_10363218_1	926569.ANT_07680	4.095e-81	290.0	COG1092@1|root,COG1092@2|Bacteria,2G7Y9@200795|Chloroflexi	200795|Chloroflexi	H	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WZS2_k127_10363218_9	1128427.KB904821_gene4604	2.246e-16	82.0	2DRDY@1|root,33BC0@2|Bacteria,1G9R7@1117|Cyanobacteria,1HCUI@1150|Oscillatoriales	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
WZS2_k127_10363218_4	1121382.JQKG01000083_gene511	8.12e-75	259.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WZS2_k127_10363218_2	1121382.JQKG01000083_gene512	6.48e-81	277.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WZS2_k127_10363218_0	926554.KI912620_gene1118	4.456e-125	411.0	COG4586@1|root,COG4586@2|Bacteria	2|Bacteria	S	(ABC) transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_10363218_7	861299.J421_0822	7.108e-34	143.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
WZS2_k127_10368058_0	1382304.JNIL01000001_gene3056	0.0	1189.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli,2793N@186823|Alicyclobacillaceae	91061|Bacilli	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06730	Aconitase,Aconitase_C
WZS2_k127_10368058_7	44689.DDB0232375	1.013e-11	76.0	COG5021@1|root,KOG0941@2759|Eukaryota	2759|Eukaryota	O	ubiquitin-protein transferase activity	-	GO:0000003,GO:0002237,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0010033,GO:0019954,GO:0032496,GO:0033993,GO:0042221,GO:0042742,GO:0043207,GO:0050896,GO:0051704,GO:0051707,GO:0098542,GO:1901700	1.14.11.4	ko:K13647,ko:K15462	ko00310,map00310	-	R03376	RC00709	ko00000,ko00001,ko01000,ko03016	-	-	-	AZUL,HECT,IQ,RCC1,RCC1_2
WZS2_k127_10368058_2	526227.Mesil_0723	1.164e-100	338.0	COG0454@1|root,COG0454@2|Bacteria,COG0456@2|Bacteria,1WJYD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_10368058_3	246194.CHY_2383	2.372e-84	289.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,42FAT@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
WZS2_k127_10368058_6	926569.ANT_04640	3.744e-52	189.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10368058_1	926569.ANT_09040	2.676e-160	521.0	COG0265@1|root,COG0265@2|Bacteria,2G821@200795|Chloroflexi	200795|Chloroflexi	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
WZS2_k127_10368058_4	926569.ANT_27050	3.259e-64	226.0	COG1695@1|root,COG1695@2|Bacteria,2G9N5@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
WZS2_k127_10368058_5	926569.ANT_27060	1.359e-62	219.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_1038829_9	926569.ANT_15450	1.222e-21	96.0	COG0598@1|root,COG0598@2|Bacteria	2|Bacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WZS2_k127_1038829_4	926569.ANT_30480	1.489e-57	209.0	COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
WZS2_k127_1038829_2	926569.ANT_08430	3.365e-65	233.0	COG1836@1|root,COG1836@2|Bacteria,2G6N3@200795|Chloroflexi	200795|Chloroflexi	S	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
WZS2_k127_1038829_8	316274.Haur_0172	8.466e-22	104.0	COG1011@1|root,COG1011@2|Bacteria,2G78N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WZS2_k127_1038829_0	926569.ANT_25450	2.656e-162	516.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
WZS2_k127_1038829_3	443144.GM21_2267	9.77e-60	210.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,42TQP@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM YbaK prolyl-tRNA synthetase associated region	ybaK	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
WZS2_k127_1038829_5	743719.PaelaDRAFT_3980	3.097e-44	168.0	COG0454@1|root,COG0456@2|Bacteria,1V2CK@1239|Firmicutes,4HGP5@91061|Bacilli,26WI0@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	yyaR	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_1038829_1	886293.Sinac_6174	4.845e-82	284.0	COG0598@1|root,COG0598@2|Bacteria,2IX61@203682|Planctomycetes	203682|Planctomycetes	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
WZS2_k127_1038829_7	926569.ANT_04540	6.009e-22	96.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WZS2_k127_10420003_5	1173024.KI912149_gene5864	2.744e-23	102.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
WZS2_k127_10420003_9	211165.AJLN01000048_gene5998	2.122e-09	60.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1JKNQ@1189|Stigonemataceae	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WZS2_k127_10420003_12	448385.sce5100	0.0009913	49.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,1R7HC@1224|Proteobacteria,43CVF@68525|delta/epsilon subdivisions,2X83D@28221|Deltaproteobacteria,2Z3K3@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,PAS_3,PAS_9,Response_reg
WZS2_k127_10420003_3	926550.CLDAP_21010	4.36e-59	214.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WZS2_k127_10420003_1	926550.CLDAP_21020	2.31e-72	249.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_10420003_10	1121456.ATVA01000011_gene1800	5.49e-09	62.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MBQT@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_10420003_6	290397.Adeh_2106	2.663e-22	101.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7V@28221|Deltaproteobacteria,2Z1U0@29|Myxococcales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WZS2_k127_10420003_7	1122947.FR7_0229	1.759e-18	87.0	COG3237@1|root,COG3237@2|Bacteria,1VFTC@1239|Firmicutes,4H8NW@909932|Negativicutes	1239|Firmicutes	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
WZS2_k127_10420003_0	1128421.JAGA01000002_gene1281	6.816e-84	293.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS2_k127_10420003_2	316274.Haur_2801	3.601e-59	220.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS2_k127_10420003_8	1484157.PSNIH2_17225	3.435e-14	83.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,3VY6Y@53335|Pantoea	1236|Gammaproteobacteria	S	UPF0761 membrane protein	rbn	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
WZS2_k127_10420003_4	365046.Rta_32680	8.708e-26	108.0	COG2261@1|root,COG2261@2|Bacteria,1N8B3@1224|Proteobacteria,2VWCP@28216|Betaproteobacteria,4AINA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WZS2_k127_10420003_11	420246.GTNG_0442	3.022e-07	54.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli,1WE9T@129337|Geobacillus	91061|Bacilli	K	helix_turn_helix, Lux Regulon	vraR	-	-	ko:K07694,ko:K11618	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WZS2_k127_10452303_3	1210884.HG799468_gene13805	1.373e-07	62.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IZGV@203682|Planctomycetes	1210884.HG799468_gene13805|-	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10452303_5	867845.KI911784_gene1399	2.653e-05	57.0	2BPXR@1|root,32IRG@2|Bacteria,2GACT@200795|Chloroflexi,376V5@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10452303_2	1121887.AUDK01000005_gene3080	5.316e-08	64.0	COG0265@1|root,COG0265@2|Bacteria,4NFCS@976|Bacteroidetes,1HXT7@117743|Flavobacteriia,2NSNQ@237|Flavobacterium	976|Bacteroidetes	O	serine protease	htrA	-	-	-	-	-	-	-	-	-	-	-	PDZ_1,PDZ_2,Trypsin_2
WZS2_k127_10452303_4	871968.DESME_08330	1.571e-06	55.0	COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,24DD0@186801|Clostridia	186801|Clostridia	L	integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
WZS2_k127_10452303_0	926569.ANT_30200	5.549e-54	207.0	COG2197@1|root,COG3055@1|root,COG2197@2|Bacteria,COG3055@2|Bacteria,2G6NU@200795|Chloroflexi	200795|Chloroflexi	KT	Kelch repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Kelch_1,Kelch_4
WZS2_k127_10452303_1	521096.Tpau_0732	3.447e-13	79.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
WZS2_k127_10493166_6	1094980.Mpsy_0054	3.117e-37	147.0	COG0642@1|root,COG2203@1|root,arCOG02348@1|root,arCOG02348@2157|Archaea,arCOG02356@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota	28890|Euryarchaeota	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_9,sCache_3_3
WZS2_k127_10493166_3	765420.OSCT_2844	1.571e-77	273.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,374Z1@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
WZS2_k127_10493166_9	1521187.JPIM01000060_gene2909	1.128e-13	84.0	2A4PD@1|root,30TAH@2|Bacteria,2GB7S@200795|Chloroflexi,377IM@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
WZS2_k127_10493166_5	926550.CLDAP_35640	5.557e-53	205.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WZS2_k127_10493166_2	525904.Tter_2275	1.348e-127	415.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WZS2_k127_10493166_11	479434.Sthe_0683	0.0001866	50.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS2_k127_10493166_7	926569.ANT_04220	1.291e-33	141.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Flavodoxin_2,UbiA
WZS2_k127_10493166_1	926569.ANT_04230	1.727e-138	451.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi	200795|Chloroflexi	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WZS2_k127_10493166_0	926550.CLDAP_16620	8.481e-203	650.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi	200795|Chloroflexi	K	PBP superfamily domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	HTH_3,MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
WZS2_k127_10493166_8	913325.N799_09990	5.967e-17	87.0	COG0784@1|root,COG2199@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1T3U3@1236|Gammaproteobacteria,1XDBR@135614|Xanthomonadales	135614|Xanthomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WZS2_k127_10493166_4	926569.ANT_04260	1.893e-66	229.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WZS2_k127_10517896_1	365044.Pnap_3364	1.558e-190	604.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,4AA5Q@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
WZS2_k127_10517896_2	765420.OSCT_3068	4.165e-86	296.0	COG2339@1|root,COG2339@2|Bacteria,2G946@200795|Chloroflexi,375Y0@32061|Chloroflexia	32061|Chloroflexia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
WZS2_k127_10517896_3	926569.ANT_22530	5.168e-47	176.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
WZS2_k127_10517896_0	926569.ANT_22520	3.515e-231	728.0	COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS2_k127_10580083_1	926569.ANT_09840	1.172e-116	383.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WZS2_k127_10580083_4	926569.ANT_09850	1.661e-30	130.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10580083_3	926569.ANT_09860	7.637e-44	167.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yyaR	-	-	ko:K06889,ko:K19273	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WZS2_k127_10580083_0	926569.ANT_09870	3.168e-156	516.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
WZS2_k127_10580083_2	926569.ANT_09880	6.577e-87	299.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	2|Bacteria	J	PFAM RNA binding S1 domain protein	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
WZS2_k127_10580083_5	1121468.AUBR01000023_gene2722	1.313e-15	83.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,42GEY@68295|Thermoanaerobacterales	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
WZS2_k127_1058654_1	926569.ANT_13390	2.164e-96	320.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
WZS2_k127_1058654_2	926569.ANT_22510	9.669e-95	317.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS2_k127_1058654_0	926569.ANT_16100	6.061e-216	681.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WZS2_k127_1058654_4	926569.ANT_16110	8.836e-45	170.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi	200795|Chloroflexi	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WZS2_k127_1058654_3	926569.ANT_19610	6.726e-53	198.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WZS2_k127_1058654_5	926569.ANT_12820	2.396e-28	126.0	COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi	200795|Chloroflexi	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1058654_6	926569.ANT_30330	2.475e-27	118.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
WZS2_k127_10625203_5	246194.CHY_0164	7.344e-05	45.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,42F4R@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WZS2_k127_10625203_3	1157490.EL26_09010	3.785e-59	212.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279PY@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WZS2_k127_10625203_0	324602.Caur_2513	1.227e-202	635.0	COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi,3766I@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM homogentisate 12-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
WZS2_k127_10625203_2	485913.Krac_3644	2.146e-94	319.0	COG0179@1|root,COG0179@2|Bacteria,2G7MW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
WZS2_k127_10625203_1	1121382.JQKG01000026_gene2918	6.364e-195	612.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
WZS2_k127_10625203_4	1283299.AUKG01000001_gene2078	2.312e-19	93.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria,4CSB4@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WZS2_k127_10627053_10	1313172.YM304_23660	2.746e-53	194.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,4CNS4@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
WZS2_k127_10627053_1	28583.AMAG_17117T0	8.979e-224	719.0	COG0151@1|root,KOG0237@2759|Eukaryota,38BPB@33154|Opisthokonta,3NXWQ@4751|Fungi	4751|Fungi	F	bifunctional purine biosynthetic protein	-	GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564	6.3.3.1,6.3.4.13	ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YGL234W,iND750.YGL234W	AIRS,AIRS_C,GARS_A,GARS_C,GARS_N
WZS2_k127_10627053_2	1313172.YM304_23690	5.523e-196	622.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4CMWP@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
WZS2_k127_10627053_4	1122222.AXWR01000014_gene1273	2.52e-131	428.0	COG0026@1|root,COG0026@2|Bacteria,1WITC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
WZS2_k127_10627053_9	1122222.AXWR01000014_gene1274	1.36e-71	246.0	COG0041@1|root,COG0041@2|Bacteria,1WJ89@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
WZS2_k127_10627053_5	243275.TDE_0686	6.583e-128	416.0	COG0152@1|root,COG0152@2|Bacteria,2J6XZ@203691|Spirochaetes	203691|Spirochaetes	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
WZS2_k127_10627053_7	243275.TDE_1405	1.503e-92	310.0	COG0047@1|root,COG0047@2|Bacteria,2J8JD@203691|Spirochaetes	203691|Spirochaetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	-	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
WZS2_k127_10627053_0	926550.CLDAP_05000	2.115e-289	917.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,2G5Z1@200795|Chloroflexi	200795|Chloroflexi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
WZS2_k127_10627053_12	1453496.AT03_12145	1.463e-32	132.0	COG0727@1|root,COG0727@2|Bacteria,1N027@1224|Proteobacteria,1S949@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S-cluster oxidoreductase	ykgJ	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
WZS2_k127_10627053_13	287.DR97_2229	3.604e-25	120.0	COG0789@1|root,COG3708@1|root,COG0789@2|Bacteria,COG3708@2|Bacteria,1REB7@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	tipA	-	-	ko:K21744	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,MerR_1,TipAS
WZS2_k127_10627053_11	103690.17129690	3.735e-40	166.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1G3NQ@1117|Cyanobacteria,1HP4J@1161|Nostocales	1117|Cyanobacteria	KT	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
WZS2_k127_10627053_3	926569.ANT_15170	2.058e-166	535.0	COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2,5.5.1.2	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	M00048,M00049	R01083,R03307,R04559	RC00379,RC00444,RC00445,RC00902	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,ASL_C,Lyase_1
WZS2_k127_10627053_6	1128421.JAGA01000002_gene306	1.314e-124	412.0	COG0104@1|root,COG0104@2|Bacteria,2NNYU@2323|unclassified Bacteria	2|Bacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WZS2_k127_10627053_8	926569.ANT_29500	9.012e-80	273.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS2_k127_10627053_14	765420.OSCT_2501	3.06e-12	72.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi,375WU@32061|Chloroflexia	32061|Chloroflexia	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10638216_4	926569.ANT_10300	8.861e-91	302.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WZS2_k127_10638216_0	926569.ANT_10310	6.552e-153	490.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WZS2_k127_10638216_11	926569.ANT_10320	8.08e-44	162.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WZS2_k127_10638216_7	926569.ANT_10330	3.057e-80	275.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WZS2_k127_10638216_9	1121434.AULY01000011_gene1758	7.244e-53	189.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2MBR8@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WZS2_k127_10638216_10	926569.ANT_10350	5.72e-52	186.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WZS2_k127_10638216_1	926569.ANT_10380	1.294e-145	477.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
WZS2_k127_10638216_6	926550.CLDAP_11780	2.063e-84	287.0	COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
WZS2_k127_10638216_5	926569.ANT_20360	1.242e-86	301.0	COG0438@1|root,COG0438@2|Bacteria,2G60E@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
WZS2_k127_10638216_13	266117.Rxyl_2442	3.498e-16	84.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
WZS2_k127_10638216_3	926569.ANT_17280	1.618e-91	307.0	COG1028@1|root,COG1028@2|Bacteria,2G8P1@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS2_k127_10638216_8	313612.L8106_13405	5.382e-65	231.0	COG1878@1|root,COG1878@2|Bacteria,1G60Q@1117|Cyanobacteria,1HHEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
WZS2_k127_10638216_2	945713.IALB_2901	9.017e-132	430.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	menC	GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C,MR_MLE_C,MR_MLE_N
WZS2_k127_10638216_12	926550.CLDAP_38940	2.713e-36	144.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi	200795|Chloroflexi	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_10668480_2	926569.ANT_19690	1.235e-146	470.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS2_k127_10668480_10	926569.ANT_19700	9.571e-61	215.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
WZS2_k127_10668480_8	1128421.JAGA01000002_gene981	1.777e-66	232.0	COG0652@1|root,COG0652@2|Bacteria,2NPSW@2323|unclassified Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
WZS2_k127_10668480_7	926569.ANT_19710	6.039e-80	273.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WZS2_k127_10668480_0	926569.ANT_01730	2.035e-173	553.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
WZS2_k127_10668480_5	926569.ANT_13730	1.153e-96	323.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WZS2_k127_10668480_9	926569.ANT_13740	3.084e-64	223.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi	200795|Chloroflexi	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
WZS2_k127_10668480_3	1128421.JAGA01000002_gene694	3.443e-101	339.0	COG1092@1|root,COG1092@2|Bacteria	2|Bacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WZS2_k127_10668480_11	926569.ANT_13760	3.459e-59	216.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WZS2_k127_10668480_4	926569.ANT_16300	5.461e-99	332.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
WZS2_k127_10668480_6	926569.ANT_03930	1.788e-92	310.0	COG1045@1|root,COG1045@2|Bacteria,2G6DI@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
WZS2_k127_10668480_1	926569.ANT_03920	5.028e-148	472.0	COG0031@1|root,COG0031@2|Bacteria,2G5PG@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS2_k127_1140346_1	266117.Rxyl_2809	8.486e-91	303.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4CRNI@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_1140346_2	266117.Rxyl_2810	1.427e-75	274.0	COG3850@1|root,COG4585@1|root,COG3850@2|Bacteria,COG4585@2|Bacteria,2GIWI@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
WZS2_k127_1140346_0	1240350.AMZE01000004_gene2501	4.674e-122	402.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMSH@1236|Gammaproteobacteria,1YYCE@136845|Pseudomonas putida group	1236|Gammaproteobacteria	G	Alpha-amylase domain	-	-	3.2.1.20,3.2.1.93	ko:K01187,ko:K01226	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R00837,R06087,R06088,R06113	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,DUF3459
WZS2_k127_1171548_3	867845.KI911784_gene2810	1.441e-108	359.0	COG0438@1|root,COG0438@2|Bacteria,2G7VI@200795|Chloroflexi,376WW@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WZS2_k127_1171548_4	383372.Rcas_0459	4.69e-103	343.0	COG1216@1|root,COG1216@2|Bacteria,2G6TR@200795|Chloroflexi,3769F@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
WZS2_k127_1171548_5	926550.CLDAP_27790	3.215e-99	341.0	COG0438@1|root,COG0438@2|Bacteria,2G6JX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
WZS2_k127_1171548_8	926550.CLDAP_27800	3.695e-63	235.0	COG3307@1|root,COG3307@2|Bacteria,2G7A2@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WZS2_k127_1171548_6	926550.CLDAP_27810	2.279e-98	329.0	COG1216@1|root,COG1216@2|Bacteria,2G8DR@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
WZS2_k127_1171548_2	357808.RoseRS_1340	3.37e-115	383.0	COG0438@1|root,COG0438@2|Bacteria,2G7W9@200795|Chloroflexi,3772B@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
WZS2_k127_1171548_1	926550.CLDAP_27830	2.686e-166	537.0	2DM58@1|root,31S4C@2|Bacteria,2GBK4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1171548_0	926550.CLDAP_27840	6.952e-169	547.0	COG5427@1|root,COG5427@2|Bacteria	2|Bacteria	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1171548_7	926550.CLDAP_27850	6.451e-81	290.0	COG4409@1|root,COG4409@2|Bacteria,2G76D@200795|Chloroflexi	200795|Chloroflexi	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
WZS2_k127_1223561_4	926569.ANT_28960	3.05e-15	77.0	COG1814@1|root,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi	200795|Chloroflexi	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WZS2_k127_1223561_2	1121924.ATWH01000001_gene4463	1.539e-50	191.0	COG1266@1|root,COG1266@2|Bacteria,2I8AH@201174|Actinobacteria,4FREE@85023|Microbacteriaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WZS2_k127_1223561_3	926569.ANT_29500	3.25e-37	150.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS2_k127_1223561_0	324602.Caur_3820	1.135e-95	346.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
WZS2_k127_1223561_1	671143.DAMO_2064	3.166e-63	224.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WZS2_k127_1227818_5	1382315.JPOI01000001_gene207	2.416e-32	126.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1WE7S@129337|Geobacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
WZS2_k127_1227818_4	1121377.KB906399_gene1660	1.068e-40	158.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WZS2_k127_1227818_2	926569.ANT_22460	8.495e-71	250.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WZS2_k127_1227818_0	926569.ANT_22450	3.739e-307	980.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
WZS2_k127_1227818_1	926569.ANT_22440	4.946e-88	307.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
WZS2_k127_1227818_7	926569.ANT_22430	1.014e-23	103.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi	200795|Chloroflexi	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WZS2_k127_1227818_3	926569.ANT_22420	2.361e-54	194.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WZS2_k127_1227818_6	926569.ANT_22410	7.272e-31	124.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi	200795|Chloroflexi	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WZS2_k127_1227818_8	926569.ANT_18000	6.125e-10	60.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
WZS2_k127_1278167_6	1122918.KB907280_gene254	1.519e-08	64.0	COG3934@1|root,COG3934@2|Bacteria,1VUFZ@1239|Firmicutes	1239|Firmicutes	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5060
WZS2_k127_1278167_1	1128421.JAGA01000004_gene2543	1.67e-289	928.0	COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria	2|Bacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WZS2_k127_1278167_3	926569.ANT_20430	1.447e-69	241.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WZS2_k127_1278167_5	926569.ANT_20440	1.705e-21	103.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1278167_4	640081.Dsui_2991	5.969e-52	211.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WGZJ@28216|Betaproteobacteria,2KVQZ@206389|Rhodocyclales	206389|Rhodocyclales	T	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,NMT1,PAS_4
WZS2_k127_1278167_0	118168.MC7420_8193	0.0	1202.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1H81U@1150|Oscillatoriales	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
WZS2_k127_1278167_2	1382356.JQMP01000003_gene2113	6.393e-158	506.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,27Y45@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl- CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS2_k127_1315565_4	309801.trd_A0636	2.281e-80	288.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi,27Z3V@189775|Thermomicrobia	189775|Thermomicrobia	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS2_k127_1315565_3	926550.CLDAP_29810	1.205e-98	329.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS2_k127_1315565_2	926569.ANT_12860	9.112e-108	354.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS2_k127_1315565_1	926569.ANT_21060	6.233e-129	422.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
WZS2_k127_1315565_0	926569.ANT_21050	2.223e-251	786.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
WZS2_k127_1421383_4	1128421.JAGA01000003_gene2755	1.975e-112	374.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WZS2_k127_1421383_5	926550.CLDAP_36410	2.373e-103	346.0	COG3507@1|root,COG3507@2|Bacteria,2G7I9@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolases family 43	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
WZS2_k127_1421383_3	1128421.JAGA01000003_gene2757	5.558e-118	386.0	COG0395@1|root,COG0395@2|Bacteria,2NQT0@2323|unclassified Bacteria	2|Bacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WZS2_k127_1421383_2	1128421.JAGA01000003_gene2758	6.149e-129	418.0	COG1175@1|root,COG1175@2|Bacteria,2NPDA@2323|unclassified Bacteria	2|Bacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WZS2_k127_1421383_1	1128421.JAGA01000003_gene2759	2.794e-129	427.0	COG1653@1|root,COG1653@2|Bacteria,2NQZ1@2323|unclassified Bacteria	2|Bacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WZS2_k127_1421383_0	926569.ANT_11470	3.403e-165	524.0	COG4189@1|root,COG4189@2|Bacteria,2G86F@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1421383_13	999547.KI421500_gene1299	5.334e-17	88.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
WZS2_k127_1421383_9	926560.KE387023_gene2407	9.418e-40	153.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WZS2_k127_1421383_6	684949.ATTJ01000002_gene334	3.425e-71	253.0	2A1VH@1|root,30Q4S@2|Bacteria,1WMIG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1421383_8	930171.Asphe3_21200	1.774e-49	186.0	2FGCJ@1|root,3488S@2|Bacteria,2H97A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1421383_7	555088.DealDRAFT_0368	4.041e-70	246.0	arCOG06802@1|root,2ZBBG@2|Bacteria,1V17K@1239|Firmicutes,24DHN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1421383_10	1499680.CCFE01000016_gene1032	9.018e-37	146.0	COG1309@1|root,COG1309@2|Bacteria,1V7QU@1239|Firmicutes,4HJIT@91061|Bacilli,1ZGD2@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yxaF	-	-	ko:K18939	-	M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_N
WZS2_k127_1421383_15	393480.FNP_1655	3.018e-09	58.0	2DDS4@1|root,2ZJ1R@2|Bacteria,37CNI@32066|Fusobacteria	32066|Fusobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1431617_1	765420.OSCT_0643	3.822e-89	313.0	COG4585@1|root,COG4585@2|Bacteria,2G7W5@200795|Chloroflexi,3767N@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1431617_0	765420.OSCT_0642	1.116e-104	350.0	COG2197@1|root,COG2197@2|Bacteria,2G7U4@200795|Chloroflexi,376QK@32061|Chloroflexia	32061|Chloroflexia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WZS2_k127_1431617_2	1128421.JAGA01000001_gene2146	1.909e-86	301.0	2CA5R@1|root,2Z81H@2|Bacteria,2NRJU@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
WZS2_k127_1431617_3	926569.ANT_23140	7.877e-10	64.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WZS2_k127_1437015_2	926550.CLDAP_26090	5.09e-69	236.0	COG3335@1|root,COG3335@2|Bacteria,2G9N4@200795|Chloroflexi	200795|Chloroflexi	L	IS630 family ISRj1-like transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
WZS2_k127_1437015_4	671143.DAMO_0416	3.081e-44	168.0	COG0784@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WZS2_k127_1437015_5	1521187.JPIM01000007_gene1369	2.268e-31	128.0	COG0642@1|root,COG2205@2|Bacteria	1521187.JPIM01000007_gene1369|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1437015_3	1144319.PMI16_04926	1.091e-55	202.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRBV@28216|Betaproteobacteria,478XB@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WZS2_k127_1437015_0	926550.CLDAP_13880	7.129e-121	404.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	4.6.1.1	ko:K01768,ko:K20977	ko00230,ko02020,ko02025,ko04113,ko04213,map00230,map02020,map02025,map04113,map04213	M00695,M00820	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF,HATPase_c,HATPase_c_2,HisKA,Response_reg,SpoIIE
WZS2_k127_1437015_1	1173263.Syn7502_01821	6.156e-120	405.0	COG0642@1|root,COG0745@1|root,COG3437@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	1.8.1.9,2.7.13.3	ko:K00384,ko:K03407	ko00450,ko02020,ko02030,map00450,map02020,map02030	M00506	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CBS,GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
WZS2_k127_1437015_6	614083.AWQR01000007_gene388	0.0001944	45.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,4AD3Y@80864|Comamonadaceae	28216|Betaproteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
WZS2_k127_1490862_5	926569.ANT_04550	9.488e-75	263.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
WZS2_k127_1490862_2	1254432.SCE1572_28920	2.14e-80	275.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
WZS2_k127_1490862_1	1173028.ANKO01000139_gene671	5.059e-124	409.0	COG1502@1|root,COG1502@2|Bacteria,1G01I@1117|Cyanobacteria,1H79E@1150|Oscillatoriales	2|Bacteria	I	TIGRFAM Competence protein ComEA, helix-hairpin-helix	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
WZS2_k127_1490862_0	926569.ANT_01340	3.372e-162	526.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WZS2_k127_1490862_7	926569.ANT_01350	1.439e-29	121.0	COG0718@1|root,COG0718@2|Bacteria	2|Bacteria	S	YbaB/EbfC DNA-binding family	ybaB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	ko:K06187,ko:K09747	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	YbaB_DNA_bd
WZS2_k127_1490862_3	926569.ANT_01360	4.383e-79	268.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi	200795|Chloroflexi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
WZS2_k127_1490862_6	926569.ANT_20950	1.313e-46	173.0	COG0735@1|root,COG0735@2|Bacteria,2G74Y@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WZS2_k127_1490862_4	383372.Rcas_1591	1.061e-75	265.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,37738@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077,ko:K09818	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
WZS2_k127_1490862_8	1131812.JQMS01000001_gene1095	4.657e-10	60.0	2EH3B@1|root,33AVB@2|Bacteria,4NXP5@976|Bacteroidetes,1I6KT@117743|Flavobacteriia,2NWVF@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1519022_1	525904.Tter_1915	1.452e-67	243.0	28NWQ@1|root,2ZBUI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1519022_2	330214.NIDE3890	2.456e-28	126.0	COG0723@1|root,COG0723@2|Bacteria,3J0TT@40117|Nitrospirae	40117|Nitrospirae	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
WZS2_k127_1519022_3	867903.ThesuDRAFT_01405	2.976e-27	117.0	298S5@1|root,313VY@2|Bacteria,1U9KD@1239|Firmicutes,25702@186801|Clostridia	186801|Clostridia	S	Protein of unknown function with PCYCGC motif	-	-	-	-	-	-	-	-	-	-	-	-	PCYCGC
WZS2_k127_1519022_5	653733.Selin_0567	2.083e-20	97.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
WZS2_k127_1519022_0	653733.Selin_0567	5.099e-96	332.0	COG0348@1|root,COG1622@1|root,COG0348@2|Bacteria,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	vnfA	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,Fer4_5,Sigma54_activat,cNMP_binding
WZS2_k127_1519022_6	118005.AWNK01000010_gene334	2.717e-12	78.0	COG4633@1|root,COG4633@2|Bacteria	2|Bacteria	-	-	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,HMA
WZS2_k127_1519022_7	216595.PFLU_1891	2.378e-07	63.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria	1224|Proteobacteria	C	COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
WZS2_k127_1548530_9	525904.Tter_0301	2.981e-30	132.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
WZS2_k127_1548530_3	1128421.JAGA01000003_gene3270	3.737e-53	194.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
WZS2_k127_1548530_13	1267534.KB906755_gene4355	0.0006682	47.0	COG4980@1|root,COG4980@2|Bacteria,3Y5HP@57723|Acidobacteria,2JJWE@204432|Acidobacteriia	204432|Acidobacteriia	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
WZS2_k127_1548530_7	1121377.KB906398_gene2665	8.76e-39	152.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_1548530_10	1128421.JAGA01000002_gene1090	1.788e-29	119.0	2BZBR@1|root,32YH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
WZS2_k127_1548530_11	479434.Sthe_2550	1.103e-22	104.0	COG0762@1|root,COG0762@2|Bacteria,2G9JK@200795|Chloroflexi,27ZAJ@189775|Thermomicrobia	189775|Thermomicrobia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1548530_8	1267535.KB906767_gene732	1.722e-36	141.0	COG1873@1|root,COG1873@2|Bacteria	2|Bacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
WZS2_k127_1548530_0	1121481.AUAS01000005_gene2121	3.68e-160	512.0	COG0446@1|root,COG0446@2|Bacteria,4NEK6@976|Bacteroidetes,47N6I@768503|Cytophagia	976|Bacteroidetes	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WZS2_k127_1548530_2	1121377.KB906400_gene1221	2.645e-59	217.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4111,NTP_transf_2
WZS2_k127_1548530_5	998674.ATTE01000001_gene3077	4.5e-48	183.0	296JA@1|root,2ZTUV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1548530_12	1094980.Mpsy_2565	6.698e-14	75.0	arCOG11924@1|root,arCOG11924@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1548530_1	296591.Bpro_1676	1.362e-114	375.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WZS2_k127_1548530_6	1476583.DEIPH_ctg040orf0015	3.906e-39	147.0	2DNXR@1|root,32ZPP@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
WZS2_k127_1548530_4	479433.Caci_5073	2.224e-52	192.0	COG2365@1|root,COG2365@2|Bacteria,2IR8R@201174|Actinobacteria	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
WZS2_k127_1554945_10	4897.EEB09259	3.478e-06	59.0	COG1716@1|root,KOG3872@2759|Eukaryota,39M6A@33154|Opisthokonta,3NXD7@4751|Fungi,3QQIM@4890|Ascomycota,3MCV4@451866|Taphrinomycotina	4751|Fungi	T	FHA domain-containing protein Far10	-	GO:0000320,GO:0000321,GO:0000749,GO:0000754,GO:0000910,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005789,GO:0005793,GO:0005815,GO:0005816,GO:0005856,GO:0006605,GO:0006623,GO:0006810,GO:0006886,GO:0007034,GO:0007049,GO:0007088,GO:0007096,GO:0007154,GO:0007165,GO:0007346,GO:0008104,GO:0008150,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010564,GO:0010646,GO:0010648,GO:0010948,GO:0010974,GO:0012505,GO:0015031,GO:0015630,GO:0015833,GO:0016020,GO:0019236,GO:0022402,GO:0023051,GO:0023052,GO:0023057,GO:0023058,GO:0031029,GO:0031030,GO:0031136,GO:0031137,GO:0031139,GO:0031929,GO:0031984,GO:0031991,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0032956,GO:0032970,GO:0032991,GO:0033036,GO:0033043,GO:0033365,GO:0034613,GO:0035556,GO:0042175,GO:0042221,GO:0042886,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043900,GO:0043902,GO:0044087,GO:0044380,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044732,GO:0045184,GO:0045786,GO:0045930,GO:0046578,GO:0046580,GO:0046907,GO:0046999,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051056,GO:0051058,GO:0051128,GO:0051129,GO:0051179,GO:0051234,GO:0051301,GO:0051302,GO:0051493,GO:0051641,GO:0051649,GO:0051716,GO:0051726,GO:0051782,GO:0051783,GO:0061492,GO:0061509,GO:0065007,GO:0070727,GO:0070887,GO:0071310,GO:0071444,GO:0071702,GO:0071705,GO:0071988,GO:0072594,GO:0072665,GO:0072666,GO:0072698,GO:0090443,GO:0098827,GO:0110020,GO:1901891,GO:1901892,GO:1901987,GO:1901990,GO:1902412,GO:1902413,GO:1902440,GO:1902531,GO:1902532,GO:1903436,GO:1903437,GO:1905508,GO:2000241,GO:2000243	-	-	-	-	-	-	-	-	-	-	FHA
WZS2_k127_1554945_0	316274.Haur_2581	1.584e-301	978.0	COG1674@1|root,COG1674@2|Bacteria,2G5Y3@200795|Chloroflexi,376BF@32061|Chloroflexia	32061|Chloroflexia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_SpoIIIE
WZS2_k127_1554945_3	316274.Haur_2580	4.057e-58	215.0	COG0515@1|root,COG0515@2|Bacteria	316274.Haur_2580|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1554945_9	316274.Haur_3851	2.408e-06	53.0	COG4842@1|root,COG4842@2|Bacteria	2|Bacteria	S	protein secretion by the type VII secretion system	-	-	-	-	-	-	-	-	-	-	-	-	Ntox44,Peptidase_C2,WXG100
WZS2_k127_1554945_11	316274.Haur_3253	6.997e-05	49.0	COG4842@1|root,COG4842@2|Bacteria	2|Bacteria	S	protein secretion by the type VII secretion system	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C2,WXG100
WZS2_k127_1554945_8	316274.Haur_4519	1.918e-08	66.0	COG1073@1|root,COG4842@1|root,COG1073@2|Bacteria,COG4842@2|Bacteria	2|Bacteria	S	protein secretion by the type VII secretion system	-	-	3.1.1.101	ko:K21104	-	-	R11540	-	ko00000,ko01000	-	-	-	Abhydrolase_5,Peptidase_C2,WXG100
WZS2_k127_1554945_12	349161.Dred_1709	0.0002014	55.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,261TT@186807|Peptococcaceae	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
WZS2_k127_1554945_5	316274.Haur_2590	3.642e-27	129.0	COG1716@1|root,COG2304@1|root,COG1716@2|Bacteria,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FHA,VWA,VWA_2,zinc_ribbon_2
WZS2_k127_1554945_13	1077974.GOEFS_115_00820	0.0003197	48.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4GE5P@85026|Gordoniaceae	201174|Actinobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_1554945_4	926569.ANT_17620	3.697e-49	183.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WZS2_k127_1554945_2	1220534.B655_1171	4.589e-101	340.0	COG0451@1|root,arCOG01369@2157|Archaea,2XUDM@28890|Euryarchaeota	28890|Euryarchaeota	M	NAD-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
WZS2_k127_1554945_1	316274.Haur_3570	1.008e-110	373.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,2GAB0@200795|Chloroflexi,374U6@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HD
WZS2_k127_1607335_4	926569.ANT_12930	1.21e-16	84.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WZS2_k127_1607335_0	926569.ANT_12940	7.754e-112	374.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WZS2_k127_1607335_3	273063.STK_08230	9.085e-36	148.0	COG1788@1|root,arCOG01987@2157|Archaea,2XQAI@28889|Crenarchaeota	28889|Crenarchaeota	I	PFAM Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS2_k127_1607335_2	926569.ANT_12960	3.596e-46	175.0	COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WZS2_k127_1607335_1	926569.ANT_12970	9.53e-87	293.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WZS2_k127_1628697_1	796606.BMMGA3_16495	5.738e-45	170.0	COG1277@1|root,COG1277@2|Bacteria,1V6DZ@1239|Firmicutes,4HFY3@91061|Bacilli,1ZCE6@1386|Bacillus	91061|Bacilli	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WZS2_k127_1628697_4	1125863.JAFN01000001_gene2793	5.326e-34	145.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
WZS2_k127_1628697_2	867903.ThesuDRAFT_02244	2.228e-39	152.0	COG0723@1|root,COG0723@2|Bacteria,1VM4K@1239|Firmicutes,24X5X@186801|Clostridia	186801|Clostridia	C	PFAM Rieske 2Fe-2S domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
WZS2_k127_1628697_3	644966.Tmar_0324	1.588e-34	142.0	COG1290@1|root,COG1290@2|Bacteria,1USWS@1239|Firmicutes,2501X@186801|Clostridia	186801|Clostridia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
WZS2_k127_1628697_0	1232410.KI421413_gene908	4.786e-71	244.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria,43UCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome b(N-terminal)/b6/petB	pcmC	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
WZS2_k127_1635716_1	926569.ANT_09770	2.768e-188	595.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WZS2_k127_1635716_2	926569.ANT_09760	1.977e-125	411.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WZS2_k127_1635716_5	926569.ANT_09750	1.015e-23	103.0	COG0851@1|root,COG0851@2|Bacteria,2G7FM@200795|Chloroflexi	200795|Chloroflexi	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
WZS2_k127_1635716_3	926569.ANT_09740	7.234e-125	404.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
WZS2_k127_1635716_4	926569.ANT_09730	4.5e-56	204.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi	200795|Chloroflexi	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
WZS2_k127_1635716_0	926569.ANT_09720	4.218e-210	669.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WZS2_k127_1663923_5	1068980.ARVW01000001_gene6166	8.43e-06	57.0	COG2909@1|root,COG4995@1|root,COG2909@2|Bacteria,COG4995@2|Bacteria,2GM3Q@201174|Actinobacteria,4DZEI@85010|Pseudonocardiales	201174|Actinobacteria	K	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
WZS2_k127_1663923_0	1254432.SCE1572_20250	2.138e-137	451.0	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS2_k127_1663923_2	1254432.SCE1572_20250	3.738e-103	344.0	COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS2_k127_1663923_1	1254432.SCE1572_20255	1.656e-116	383.0	COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,42TEH@68525|delta/epsilon subdivisions,2WPV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS2_k127_1663923_3	1254432.SCE1572_20260	1.932e-92	314.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria,2Z08T@29|Myxococcales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS2_k127_1663923_4	1254432.SCE1572_20265	8.285e-08	55.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2YV0S@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS2_k127_1684259_19	744980.TRICHSKD4_2342	0.0003703	43.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WZS2_k127_1684259_6	748247.AZKH_4272	1.659e-73	256.0	COG3568@1|root,COG3568@2|Bacteria,1PPNP@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
WZS2_k127_1684259_5	867845.KI911784_gene2183	9.976e-99	342.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,376AC@32061|Chloroflexia	32061|Chloroflexia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WZS2_k127_1684259_1	926569.ANT_03460	1.748e-236	745.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WZS2_k127_1684259_3	1128421.JAGA01000001_gene2047	1.962e-118	388.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WZS2_k127_1684259_16	756272.Plabr_1034	1.518e-06	60.0	COG2010@1|root,COG2319@1|root,COG2010@2|Bacteria,COG2319@2|Bacteria,2IY5Q@203682|Planctomycetes	203682|Planctomycetes	M	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt1,PSCyt2,PSD1,WD40
WZS2_k127_1684259_11	1267535.KB906767_gene3015	1.279e-23	114.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3Y4F0@57723|Acidobacteria,2JKSY@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C
WZS2_k127_1684259_7	330214.NIDE3889	3.376e-70	243.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
WZS2_k127_1684259_12	234267.Acid_6209	5.024e-21	99.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
WZS2_k127_1684259_17	644966.Tmar_0118	2.302e-06	55.0	COG2009@1|root,COG2009@2|Bacteria,1VKGI@1239|Firmicutes,24VB1@186801|Clostridia	186801|Clostridia	C	TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WZS2_k127_1684259_15	485913.Krac_8731	3.296e-07	57.0	COG2142@1|root,COG2142@2|Bacteria,2G7EN@200795|Chloroflexi	200795|Chloroflexi	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	-	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
WZS2_k127_1684259_0	926569.ANT_22150	3.994e-298	923.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WZS2_k127_1684259_4	479434.Sthe_0996	5.865e-104	343.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi,27XI2@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10
WZS2_k127_1684259_10	926560.KE387027_gene1046	2.489e-41	165.0	COG2334@1|root,COG2334@2|Bacteria,1WMJ1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WZS2_k127_1684259_8	1121920.AUAU01000004_gene587	3.413e-56	199.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WZS2_k127_1684259_14	1094980.Mpsy_2100	2.255e-11	68.0	COG1977@1|root,arCOG00536@2157|Archaea,2Y6GH@28890|Euryarchaeota,2NA3I@224756|Methanomicrobia	224756|Methanomicrobia	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
WZS2_k127_1684259_2	1541960.KQ78_00863	2.116e-124	410.0	COG2414@1|root,COG2414@2|Bacteria	2|Bacteria	C	aldehyde ferredoxin oxidoreductase activity	aor	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS09915	AFOR_C,AFOR_N
WZS2_k127_1719859_1	926569.ANT_30870	3.937e-84	284.0	COG0586@1|root,COG0586@2|Bacteria,2G79V@200795|Chloroflexi	200795|Chloroflexi	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
WZS2_k127_1719859_2	926569.ANT_18900	3.528e-51	192.0	COG0340@1|root,COG0340@2|Bacteria,2G6WF@200795|Chloroflexi	200795|Chloroflexi	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
WZS2_k127_1719859_0	926569.ANT_03530	0.0	1121.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WZS2_k127_1723741_3	926569.ANT_25100	3.777e-86	287.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
WZS2_k127_1723741_2	926569.ANT_25090	2.567e-87	302.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1723741_4	926569.ANT_00310	5.49e-86	306.0	COG0651@1|root,COG0651@2|Bacteria,2G9I2@200795|Chloroflexi	200795|Chloroflexi	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
WZS2_k127_1723741_0	926569.ANT_00270	1.412e-227	712.0	COG0044@1|root,COG0044@2|Bacteria,2G5N4@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
WZS2_k127_1723741_6	485913.Krac_10276	6.799e-37	150.0	COG0801@1|root,COG0801@2|Bacteria,2G6YT@200795|Chloroflexi	200795|Chloroflexi	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
WZS2_k127_1723741_1	5786.XP_003285227.1	5.293e-124	407.0	COG0183@1|root,KOG1391@2759|Eukaryota,3X9KZ@554915|Amoebozoa	554915|Amoebozoa	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
WZS2_k127_1735771_4	382464.ABSI01000011_gene3046	5.71e-68	238.0	COG1409@1|root,COG1409@2|Bacteria,46XGN@74201|Verrucomicrobia,2IVV6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WZS2_k127_1735771_8	655815.ZPR_4218	9.415e-07	57.0	COG1409@1|root,COG1409@2|Bacteria,4NJN7@976|Bacteroidetes,1I0JE@117743|Flavobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WZS2_k127_1735771_5	235909.GK2275	2.288e-42	164.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1WEZR@129337|Geobacillus	91061|Bacilli	K	UTRA	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS2_k127_1735771_2	1408254.T458_22015	3.688e-106	351.0	COG0434@1|root,COG0434@2|Bacteria,1TT5Y@1239|Firmicutes,4HFMY@91061|Bacilli	91061|Bacilli	S	BtpA family	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
WZS2_k127_1735771_0	312284.A20C1_10189	1.899e-163	527.0	COG1653@1|root,COG1653@2|Bacteria,2GNI2@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	GO:0003674,GO:0005488,GO:0006810,GO:0008150,GO:0008643,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0030246,GO:0042221,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071702,GO:1901700,GO:1901701	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WZS2_k127_1735771_3	312284.A20C1_10194	8.652e-90	306.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WZS2_k127_1735771_1	312284.A20C1_10199	9.604e-107	353.0	COG0395@1|root,COG0395@2|Bacteria,2GN84@201174|Actinobacteria,3UWSW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WZS2_k127_1735771_6	420247.Msm_1389	1.522e-31	136.0	COG0524@1|root,arCOG00014@2157|Archaea,2XU7Z@28890|Euryarchaeota,23NQZ@183925|Methanobacteria	183925|Methanobacteria	G	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.213,2.7.1.73	ko:K22026	ko00230,ko00240,map00230,map00240	-	R00513,R01131,R01228	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WZS2_k127_1735771_7	706433.HMPREF9430_00504	3.503e-19	97.0	COG2159@1|root,COG2159@2|Bacteria,1V411@1239|Firmicutes,3VUPR@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WZS2_k127_1805150_6	926550.CLDAP_02830	3.693e-53	188.0	COG2131@1|root,COG2131@2|Bacteria,2G7AC@200795|Chloroflexi	200795|Chloroflexi	F	MafB19-like deaminase	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
WZS2_k127_1805150_3	525904.Tter_1441	3.934e-114	379.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_1805150_10	525904.Tter_1442	1.831e-38	154.0	COG4587@1|root,COG4587@2|Bacteria,2NQY6@2323|unclassified Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WZS2_k127_1805150_8	1382306.JNIM01000001_gene1765	2.045e-43	168.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WZS2_k127_1805150_11	1120999.JONM01000011_gene1670	8.03e-34	140.0	COG2453@1|root,COG2453@2|Bacteria,1QZXA@1224|Proteobacteria	1224|Proteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
WZS2_k127_1805150_15	331869.BAL199_08043	8.903e-17	89.0	2CA4Z@1|root,32W4Q@2|Bacteria,1N3RF@1224|Proteobacteria,2UDC8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1805150_9	926569.ANT_29040	1.456e-42	167.0	COG3464@1|root,COG3464@2|Bacteria,2G9B1@200795|Chloroflexi	200795|Chloroflexi	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
WZS2_k127_1805150_1	926569.ANT_14290	4.181e-175	577.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,2G6NM@200795|Chloroflexi	200795|Chloroflexi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
WZS2_k127_1805150_7	2002.JOEQ01000008_gene1128	9.058e-48	178.0	COG1051@1|root,COG1051@2|Bacteria,2GP4Y@201174|Actinobacteria,4EIYF@85012|Streptosporangiales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS2_k127_1805150_12	580340.Tlie_1690	2.723e-26	111.0	COG1917@1|root,COG1917@2|Bacteria,3TBRD@508458|Synergistetes	508458|Synergistetes	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WZS2_k127_1805150_2	658086.HMPREF0994_03296	1.066e-154	502.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,27K8I@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Glutamine synthetase, beta-Grasp domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WZS2_k127_1805150_13	134676.ACPL_3000	3.748e-23	101.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4DEUQ@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
WZS2_k127_1805150_16	1268072.PSAB_23725	4.189e-13	82.0	COG1524@1|root,COG1524@2|Bacteria,1TRZ7@1239|Firmicutes,4HAY5@91061|Bacilli,26T6G@186822|Paenibacillaceae	91061|Bacilli	S	nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
WZS2_k127_1805150_0	926569.ANT_11300	2.609e-192	617.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WZS2_k127_1805150_14	926569.ANT_11310	1.353e-19	91.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
WZS2_k127_1805150_4	926569.ANT_11320	1.903e-111	371.0	COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_1805150_5	383372.Rcas_0525	9.255e-56	212.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
WZS2_k127_1822385_1	926569.ANT_24850	4.03e-180	574.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WZS2_k127_1822385_4	926569.ANT_24870	2.433e-69	241.0	COG1418@1|root,COG1418@2|Bacteria,2G77Y@200795|Chloroflexi	200795|Chloroflexi	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
WZS2_k127_1822385_2	926569.ANT_05870	5.884e-83	280.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	pilL	GO:0003674,GO:0005488,GO:0005515,GO:0019904	2.7.13.3	ko:K02487,ko:K03407,ko:K03413,ko:K06596,ko:K11526,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507,M00508,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
WZS2_k127_1822385_5	56780.SYN_00928	3.255e-65	233.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2MR8P@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	PFAM inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WZS2_k127_1822385_3	926569.ANT_30490	1.831e-75	262.0	COG0496@1|root,COG0496@2|Bacteria	2|Bacteria	P	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WZS2_k127_1822385_0	926550.CLDAP_06400	0.0	1212.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WZS2_k127_1867741_1	926550.CLDAP_29780	2.126e-65	239.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WZS2_k127_1867741_0	326427.Cagg_2100	4.466e-153	494.0	COG3844@1|root,COG3844@2|Bacteria,2G5K1@200795|Chloroflexi,3767U@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WZS2_k127_1867741_2	1379270.AUXF01000004_gene3339	1.987e-23	111.0	COG0223@1|root,COG1657@1|root,COG0223@2|Bacteria,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	pelE	-	2.1.2.2,2.1.2.9,3.4.11.10,3.4.11.6,4.2.2.2	ko:K00604,ko:K01728,ko:K11175,ko:K19701	ko00040,ko00230,ko00670,ko00970,ko01100,ko01110,ko01130,ko02024,map00040,map00230,map00670,map00970,map01100,map01110,map01130,map02024	M00048	R02361,R03940,R04325,R04326,R06240	RC00026,RC00049,RC00165,RC00197,RC00705,RC01128	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	CBM_6,Formyl_trans_C,Formyl_trans_N,Pec_lyase
WZS2_k127_1867741_3	316274.Haur_3745	6.394e-16	84.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K03281,ko:K08714,ko:K16922	-	-	-	-	ko00000,ko01002,ko02000	1.A.1.14,2.A.49	-	-	CBS,Ion_trans,NTP_transferase,TIR-like,cNMP_binding
WZS2_k127_1909160_4	1492922.GY26_12850	3.344e-22	102.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1J6YM@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	iECDH1ME8569_1439.ECDH1ME8569_2955,iECSE_1348.ECSE_3338,iPC815.YPO0648,iSBO_1134.SBO_2914,iSDY_1059.SDY_3241,iSFxv_1172.SFxv_3403,iUTI89_1310.UTI89_C3494,iYL1228.KPN_03462,ic_1306.c3808	FolB
WZS2_k127_1909160_1	1385518.N798_03220	3.247e-133	435.0	COG1404@1|root,COG1404@2|Bacteria,2GJYH@201174|Actinobacteria,4FF4Q@85021|Intrasporangiaceae	201174|Actinobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I9,Peptidase_S8
WZS2_k127_1909160_2	593750.Metfor_2198	5.25e-39	161.0	COG2208@1|root,arCOG02362@1|root,arCOG02362@2157|Archaea,arCOG06893@2157|Archaea,2Y2MD@28890|Euryarchaeota	2157|Archaea	T	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
WZS2_k127_1909160_0	926569.ANT_19970	0.0	1023.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WZS2_k127_1909160_6	107636.JQNK01000009_gene1986	2.367e-05	46.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TRE4@28211|Alphaproteobacteria,370IU@31993|Methylocystaceae	28211|Alphaproteobacteria	L	dna methylase	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
WZS2_k127_1909160_3	658187.LDG_7326	5.781e-39	156.0	COG2267@1|root,COG2267@2|Bacteria,1QYYZ@1224|Proteobacteria,1T6WZ@1236|Gammaproteobacteria,1JEFF@118969|Legionellales	118969|Legionellales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
WZS2_k127_1909160_5	383372.Rcas_3580	4.529e-12	74.0	COG1664@1|root,COG1664@2|Bacteria,2G79N@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2067420_1	926569.ANT_00370	3.844e-42	172.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS2_k127_2067420_2	926569.ANT_00380	3.749e-28	123.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2067420_0	671143.DAMO_0346	1.155e-69	258.0	COG1070@1|root,COG1070@2|Bacteria,2NP2A@2323|unclassified Bacteria	2|Bacteria	G	MutL protein	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N,MutL
WZS2_k127_2067420_3	926569.ANT_00400	0.0002798	45.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2100289_1	1499967.BAYZ01000061_gene5931	1.452e-103	345.0	COG0366@1|root,COG0366@2|Bacteria,2NP2D@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	nplT	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
WZS2_k127_2100289_0	326427.Cagg_3180	3.998e-169	552.0	COG0366@1|root,COG0366@2|Bacteria,2G7J7@200795|Chloroflexi,377YN@32061|Chloroflexia	32061|Chloroflexia	G	Alpha-amylase domain	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
WZS2_k127_2100289_2	215803.DB30_4039	4.084e-96	325.0	COG2382@1|root,COG2382@2|Bacteria,1MXJN@1224|Proteobacteria,437I8@68525|delta/epsilon subdivisions,2X38I@28221|Deltaproteobacteria,2YVT6@29|Myxococcales	28221|Deltaproteobacteria	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
WZS2_k127_2100289_5	511051.CSE_03850	2.173e-12	80.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K15770,ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1,Cu_amine_oxidN1,SBP_bac_8
WZS2_k127_2100289_4	926569.ANT_18580	4.204e-42	163.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
WZS2_k127_2100289_3	290317.Cpha266_1585	1.71e-52	188.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	DUF1735,Laminin_G_3,Patatin
WZS2_k127_2117383_6	1123247.AUIJ01000002_gene2297	0.0001459	51.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,2TTFW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the peptidase M50B family	-	-	-	ko:K06402	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBS,Peptidase_M50
WZS2_k127_2117383_1	926569.ANT_05390	6.305e-124	404.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
WZS2_k127_2117383_0	926569.ANT_05380	1.203e-156	501.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi	200795|Chloroflexi	H	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
WZS2_k127_2117383_4	452652.KSE_33690	2.069e-25	113.0	COG1595@1|root,COG1595@2|Bacteria,2GJER@201174|Actinobacteria,2M0Z0@2063|Kitasatospora	201174|Actinobacteria	K	ECF sigma factor	adsA	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS2_k127_2117383_5	33898.JRHJ01000101_gene7926	1.232e-06	60.0	COG3170@1|root,COG3170@2|Bacteria,2GJWK@201174|Actinobacteria	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2117383_2	1128421.JAGA01000002_gene1836	7.727e-83	291.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
WZS2_k127_2117383_3	926569.ANT_13210	5.519e-70	239.0	COG2403@1|root,COG2403@2|Bacteria,2G7VS@200795|Chloroflexi	200795|Chloroflexi	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2253467_3	1128421.JAGA01000002_gene371	2.132e-97	326.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria	2|Bacteria	C	synthetase (ADP forming), alpha	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
WZS2_k127_2253467_1	324602.Caur_3302	2.342e-123	402.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,377SH@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
WZS2_k127_2253467_0	926550.CLDAP_16500	3.696e-145	467.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
WZS2_k127_2253467_2	1499967.BAYZ01000018_gene6344	1.974e-120	398.0	COG3191@1|root,COG3191@2|Bacteria,2NNR0@2323|unclassified Bacteria	2|Bacteria	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WZS2_k127_2253467_4	926550.CLDAP_00430	7.407e-65	231.0	COG0300@1|root,COG0300@2|Bacteria,2G8X2@200795|Chloroflexi	200795|Chloroflexi	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
WZS2_k127_2253467_5	1121374.KB891585_gene2413	4.288e-51	188.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,1S71V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WZS2_k127_2350656_6	926569.ANT_01260	1.36e-147	473.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS2_k127_2350656_4	765420.OSCT_2196	3.08e-148	480.0	COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi	200795|Chloroflexi	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
WZS2_k127_2350656_3	864702.OsccyDRAFT_1800	8.11e-154	500.0	COG3845@1|root,COG3845@2|Bacteria,1G4UA@1117|Cyanobacteria,1HH79@1150|Oscillatoriales	1117|Cyanobacteria	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WZS2_k127_2350656_8	864702.OsccyDRAFT_1416	3.122e-99	334.0	COG4603@1|root,COG4603@2|Bacteria	2|Bacteria	L	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS2_k127_2350656_9	1158318.ATXC01000001_gene666	9.739e-98	329.0	COG1079@1|root,COG1079@2|Bacteria	2|Bacteria	S	Belongs to the binding-protein-dependent transport system permease family	rbsC-2	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS2_k127_2350656_2	926569.ANT_04670	4.434e-173	553.0	COG0498@1|root,COG0498@2|Bacteria,2G6D6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS2_k127_2350656_11	670487.Ocepr_0159	7.247e-44	162.0	COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
WZS2_k127_2350656_7	452637.Oter_1765	6.418e-103	338.0	COG1215@1|root,COG1215@2|Bacteria,46SRA@74201|Verrucomicrobia,3K7C7@414999|Opitutae	414999|Opitutae	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WZS2_k127_2350656_5	926569.ANT_04660	1.09e-147	473.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
WZS2_k127_2350656_1	926569.ANT_04650	7.519e-247	769.0	COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
WZS2_k127_2350656_0	357808.RoseRS_3980	8.23e-317	1002.0	COG0553@1|root,COG0553@2|Bacteria,2G7XH@200795|Chloroflexi,374UT@32061|Chloroflexia	32061|Chloroflexia	KL	PFAM SNF2-related protein	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
WZS2_k127_2350656_10	84531.JMTZ01000005_gene2391	2.592e-96	345.0	COG2304@1|root,COG2304@2|Bacteria,1R8EZ@1224|Proteobacteria,1SG9K@1236|Gammaproteobacteria,1XB1U@135614|Xanthomonadales	135614|Xanthomonadales	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
WZS2_k127_2350656_12	926569.ANT_27070	5.295e-33	130.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS2_k127_2424797_5	290512.Paes_1085	9.104e-64	222.0	COG0433@1|root,COG0433@2|Bacteria,1FEIF@1090|Chlorobi	1090|Chlorobi	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
WZS2_k127_2424797_4	1128421.JAGA01000002_gene1498	5.76e-72	256.0	COG1502@1|root,COG1502@2|Bacteria,2NQ5Z@2323|unclassified Bacteria	2|Bacteria	I	PLD-like domain	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
WZS2_k127_2424797_0	926569.ANT_25310	5.025e-102	345.0	COG1996@1|root,COG1996@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
WZS2_k127_2424797_1	926569.ANT_25300	8.907e-96	323.0	COG2888@1|root,COG2888@2|Bacteria	2|Bacteria	J	peptidyl-tyrosine sulfation	ybeL	-	1.17.4.1,4.6.1.1	ko:K00525,ko:K01768	ko00230,ko00240,ko01100,ko02025,ko04113,ko04213,map00230,map00240,map01100,map02025,map04113,map04213	M00053,M00695	R00089,R00434,R02017,R02018,R02019,R02024	RC00295,RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	DUF1451
WZS2_k127_2424797_6	1266909.AUAG01000015_gene2704	2.922e-47	188.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1SYRX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Protoglobin
WZS2_k127_2424797_2	926569.ANT_00640	2.368e-74	253.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WZS2_k127_2424797_3	1499967.BAYZ01000095_gene4087	3.831e-73	253.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
WZS2_k127_2426579_4	867903.ThesuDRAFT_01142	1.728e-112	389.0	COG1139@1|root,COG1556@1|root,COG1139@2|Bacteria,COG1556@2|Bacteria,1TREQ@1239|Firmicutes,24BXS@186801|Clostridia	186801|Clostridia	C	Iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
WZS2_k127_2426579_1	526227.Mesil_0360	2.551e-144	475.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
WZS2_k127_2426579_12	926569.ANT_15380	6.035e-35	144.0	COG2353@1|root,COG2353@2|Bacteria,2G73S@200795|Chloroflexi	200795|Chloroflexi	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WZS2_k127_2426579_9	926569.ANT_09630	4.871e-68	241.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi	200795|Chloroflexi	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
WZS2_k127_2426579_0	926569.ANT_09640	1.064e-152	490.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WZS2_k127_2426579_10	1295642.H839_09503	1.943e-58	214.0	COG0697@1|root,COG0697@2|Bacteria,1UH2I@1239|Firmicutes,4HCFV@91061|Bacilli,1WE3H@129337|Geobacillus	91061|Bacilli	EG	EamA-like transporter family	gmT1	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS2_k127_2426579_5	756067.MicvaDRAFT_1623	1.149e-107	364.0	COG0683@1|root,COG0683@2|Bacteria,1G16P@1117|Cyanobacteria,1H80W@1150|Oscillatoriales	1117|Cyanobacteria	E	Receptor family ligand binding region	natB	-	-	ko:K01999,ko:K11954	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ANF_receptor,Peripla_BP_6
WZS2_k127_2426579_3	1173027.Mic7113_0201	3.397e-117	390.0	COG0559@1|root,COG0559@2|Bacteria,1G3S0@1117|Cyanobacteria,1H9UM@1150|Oscillatoriales	1117|Cyanobacteria	E	transport system permease	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS2_k127_2426579_2	1170562.Cal6303_5526	6.996e-138	456.0	COG4177@1|root,COG4177@2|Bacteria,1G1YV@1117|Cyanobacteria,1HKZJ@1161|Nostocales	2|Bacteria	U	PFAM Branched-chain amino acid transport system permease component	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS2_k127_2426579_8	1487953.JMKF01000025_gene2361	4.109e-96	321.0	COG0411@1|root,COG0411@2|Bacteria,1G07Z@1117|Cyanobacteria,1H9QZ@1150|Oscillatoriales	1117|Cyanobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS2_k127_2426579_6	1128421.JAGA01000002_gene1298	1.462e-104	344.0	COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria	2|Bacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WZS2_k127_2426579_11	926550.CLDAP_31590	1.119e-54	199.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,2G63D@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
WZS2_k127_2426579_7	1283300.ATXB01000001_gene1920	6.061e-100	335.0	COG1063@1|root,COG1063@2|Bacteria,1MW7C@1224|Proteobacteria,1RYJU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
WZS2_k127_2441152_2	1218076.BAYB01000014_gene3044	8.805e-93	313.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2VJ5U@28216|Betaproteobacteria,1K0E0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
WZS2_k127_2441152_3	926569.ANT_19500	7.391e-58	205.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	rfaH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
WZS2_k127_2441152_0	383372.Rcas_4308	2.131e-257	807.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi,376A2@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
WZS2_k127_2441152_4	1134912.AJTV01000007_gene1027	3.07e-39	150.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,36YKK@31993|Methylocystaceae	28211|Alphaproteobacteria	J	RF-1 domain	MA20_05665	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
WZS2_k127_2441152_1	926550.CLDAP_00330	2.062e-195	619.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WZS2_k127_2441152_5	326427.Cagg_1689	7.464e-19	88.0	COG1472@1|root,COG1472@2|Bacteria,2G84T@200795|Chloroflexi,3759W@32061|Chloroflexia	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WZS2_k127_2541170_6	926569.ANT_00370	6.001e-10	70.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS2_k127_2541170_4	926569.ANT_00360	8.117e-26	114.0	2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2541170_2	926569.ANT_00350	2.877e-54	199.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2541170_0	552811.Dehly_0399	8.996e-245	772.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,34CKH@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS2_k127_2541170_3	391615.ABSJ01000014_gene1622	4.161e-35	143.0	2AYXV@1|root,31R3M@2|Bacteria,1RHPG@1224|Proteobacteria,1SYAS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2541170_1	926569.ANT_29680	2.035e-86	290.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS2_k127_257485_2	1254432.SCE1572_07155	2.444e-156	505.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,2YWBV@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
WZS2_k127_257485_0	926569.ANT_27190	6e-244	768.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	mdlB	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS2_k127_257485_4	405948.SACE_3168	1.637e-65	226.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4E5A2@85010|Pseudonocardiales	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
WZS2_k127_257485_3	324602.Caur_2583	1.313e-148	476.0	COG4447@1|root,COG4447@2|Bacteria,2G5ZD@200795|Chloroflexi	200795|Chloroflexi	S	BNR/Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR
WZS2_k127_257485_6	1394178.AWOO02000071_gene381	2.565e-35	137.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4EPKG@85012|Streptosporangiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
WZS2_k127_257485_1	697281.Mahau_2687	2.267e-159	525.0	COG3533@1|root,COG3533@2|Bacteria,1TRV9@1239|Firmicutes,24CKP@186801|Clostridia	186801|Clostridia	G	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
WZS2_k127_257485_7	926569.ANT_02560	1.087e-34	139.0	COG1595@1|root,COG1595@2|Bacteria,2G96E@200795|Chloroflexi	200795|Chloroflexi	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS2_k127_257485_5	324602.Caur_2627	2.583e-48	175.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS2_k127_2589192_0	1521187.JPIM01000134_gene1347	2.969e-130	423.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
WZS2_k127_2589192_3	357808.RoseRS_1504	1.098e-45	175.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
WZS2_k127_2589192_2	1458462.JNLK01000001_gene213	1.112e-87	295.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,27IMS@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WZS2_k127_2589192_4	1121396.KB893113_gene3209	1.469e-18	90.0	COG0726@1|root,COG0726@2|Bacteria,1RH3I@1224|Proteobacteria,42T75@68525|delta/epsilon subdivisions,2WPC1@28221|Deltaproteobacteria,2MK87@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Archaea-specific editing domain of threonyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	tRNA-Thr_ED
WZS2_k127_2589192_1	1009370.ALO_01789	3.662e-121	397.0	COG1814@1|root,COG1814@2|Bacteria,1UQWP@1239|Firmicutes,4H8S9@909932|Negativicutes	909932|Negativicutes	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WZS2_k127_2646403_6	1043205.AFYF01000065_gene2194	5.325e-10	71.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4FGFE@85021|Intrasporangiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_2646403_1	926569.ANT_06870	4.814e-123	406.0	COG0111@1|root,COG0111@2|Bacteria,2G6KY@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS2_k127_2646403_4	1499967.BAYZ01000159_gene478	8.844e-47	177.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WZS2_k127_2646403_2	926569.ANT_25850	2.44e-90	312.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WZS2_k127_2646403_0	641491.DND132_1003	1.105e-208	657.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2X6YF@28221|Deltaproteobacteria,2M8DU@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Fumarate lyase	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1,cNMP_binding
WZS2_k127_2646403_3	1121920.AUAU01000002_gene2100	7.771e-66	226.0	COG2759@1|root,COG2759@2|Bacteria,3Y338@57723|Acidobacteria	57723|Acidobacteria	F	Formate--tetrahydrofolate ligase	-	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WZS2_k127_280135_0	313624.NSP_33190	1.587e-94	351.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1GHCI@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CBS,CheB_methylest,CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9
WZS2_k127_2813441_8	1198452.Jab_2c06290	1.28e-14	74.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,476XW@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS2_k127_2813441_9	1089551.KE386572_gene649	1.503e-08	62.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,4BQ8Z@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WZS2_k127_2813441_6	926569.ANT_05250	1.509e-43	169.0	COG3346@1|root,COG3346@2|Bacteria	2|Bacteria	S	mitochondrial respiratory chain complex IV assembly	surf1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
WZS2_k127_2813441_5	324602.Caur_0566	2.38e-49	183.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,375R3@32061|Chloroflexia	32061|Chloroflexia	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WZS2_k127_2813441_2	926569.ANT_05280	8.962e-72	247.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
WZS2_k127_2813441_0	926569.ANT_05300	1.765e-252	793.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WZS2_k127_2813441_1	926569.ANT_05310	8.665e-111	379.0	COG1622@1|root,COG2010@1|root,COG2197@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,COG2197@2|Bacteria,2G6C0@200795|Chloroflexi	200795|Chloroflexi	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
WZS2_k127_2813441_3	926569.ANT_04310	2.534e-71	247.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_2813441_4	926569.ANT_04300	2.99e-58	216.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K03406,ko:K07673,ko:K07675	ko02020,ko02030,map02020,map02030	M00471,M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,LapD_MoxY_N
WZS2_k127_2838539_7	880072.Desac_0663	1.993e-18	90.0	COG3315@1|root,COG3315@2|Bacteria,1RAX6@1224|Proteobacteria,42RC4@68525|delta/epsilon subdivisions,2WN5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
WZS2_k127_2838539_6	760192.Halhy_6015	2.666e-25	113.0	COG2253@1|root,COG2253@2|Bacteria,4NKE9@976|Bacteroidetes,1IRWJ@117747|Sphingobacteriia	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WZS2_k127_2838539_2	684949.ATTJ01000002_gene265	2.369e-127	416.0	COG2132@1|root,COG2132@2|Bacteria,1WJQI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
WZS2_k127_2838539_3	479434.Sthe_3148	1.654e-104	352.0	COG0428@1|root,COG0428@2|Bacteria,2G9IR@200795|Chloroflexi	200795|Chloroflexi	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2838539_4	926550.CLDAP_26730	1.579e-73	254.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi	200795|Chloroflexi	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WZS2_k127_2838539_1	926569.ANT_11420	2.498e-155	494.0	COG3940@1|root,COG3940@2|Bacteria,2G8V8@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
WZS2_k127_2838539_0	864069.MicloDRAFT_00058430	7.482e-210	682.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,2U2CB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WZS2_k127_2838539_5	1128421.JAGA01000003_gene2755	1.3e-41	158.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WZS2_k127_284850_3	443143.GM18_0058	8.409e-28	126.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,EF-hand_5,FGE-sulfatase,Lactamase_B_2,PD40,Peptidase_S9
WZS2_k127_284850_4	1101195.Meth11DRAFT_0507	5.175e-09	60.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1RGKE@1224|Proteobacteria,2W216@28216|Betaproteobacteria,2KN13@206350|Nitrosomonadales	206350|Nitrosomonadales	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WZS2_k127_284850_1	1232410.KI421418_gene2169	2.145e-73	250.0	COG1145@1|root,COG1145@2|Bacteria,1NUEE@1224|Proteobacteria,42ZMC@68525|delta/epsilon subdivisions,2WUUG@28221|Deltaproteobacteria,43UQ0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2867621_0	926569.ANT_05230	5.182e-268	835.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WZS2_k127_2867621_3	926569.ANT_02530	6e-96	324.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi	200795|Chloroflexi	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WZS2_k127_2867621_2	926569.ANT_02520	1.24e-105	353.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WZS2_k127_2867621_4	926569.ANT_02510	8.76e-68	241.0	COG1120@1|root,COG1120@2|Bacteria,2G6QS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WZS2_k127_2867621_5	1049564.TevJSym_ar00440	1.716e-24	110.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
WZS2_k127_2867621_6	1459636.NTE_02670	0.0002089	49.0	arCOG09395@1|root,arCOG12828@1|root,arCOG09395@2157|Archaea,arCOG12828@2157|Archaea,41T04@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
WZS2_k127_2867621_1	926569.ANT_23760	5.02e-107	357.0	COG0040@1|root,COG0040@2|Bacteria,2G6DD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
WZS2_k127_2874322_7	1463879.JOHP01000019_gene2568	8.592e-15	82.0	COG0477@1|root,COG2814@2|Bacteria,2GJU2@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS2_k127_2874322_0	383372.Rcas_0084	2.639e-169	539.0	COG0667@1|root,COG0667@2|Bacteria,2G5V3@200795|Chloroflexi,377XZ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS2_k127_2874322_1	1122915.AUGY01000027_gene3527	1.217e-131	441.0	COG4586@1|root,COG4587@1|root,COG4586@2|Bacteria,COG4587@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli,26R39@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WZS2_k127_2874322_3	697284.ERIC2_c09080	3.014e-64	228.0	COG3694@1|root,COG3694@2|Bacteria,1V1MN@1239|Firmicutes,4HFXH@91061|Bacilli,26S9D@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WZS2_k127_2874322_5	326427.Cagg_0064	1.447e-35	143.0	COG3937@1|root,COG5394@1|root,COG3937@2|Bacteria,COG5394@2|Bacteria,2G77C@200795|Chloroflexi,375VS@32061|Chloroflexia	32061|Chloroflexia	K	PFAM PHA accumulation regulator DNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
WZS2_k127_2874322_6	357808.RoseRS_4398	5.268e-20	93.0	COG3937@1|root,COG3937@2|Bacteria,2G7GR@200795|Chloroflexi,375WV@32061|Chloroflexia	32061|Chloroflexia	S	Poly(hydroxyalcanoate) granule associated protein (phasin)	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
WZS2_k127_2874322_4	316274.Haur_2223	3.621e-38	147.0	COG1454@1|root,COG1454@2|Bacteria,2GBSR@200795|Chloroflexi,375PH@32061|Chloroflexia	32061|Chloroflexia	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2874322_2	316274.Haur_1672	3.631e-75	267.0	COG0451@1|root,COG0451@2|Bacteria,2GADR@200795|Chloroflexi,375N9@32061|Chloroflexia	32061|Chloroflexia	GM	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WZS2_k127_2907279_4	926569.ANT_02380	3.566e-122	398.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WZS2_k127_2907279_1	926569.ANT_01210	9.879e-228	712.0	COG0402@1|root,COG0402@2|Bacteria,2G5X1@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS2_k127_2907279_0	926569.ANT_01220	9.133e-263	820.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
WZS2_k127_2907279_5	926569.ANT_01230	4.095e-66	233.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS2_k127_2907279_2	926569.ANT_01240	7.807e-218	680.0	COG0624@1|root,COG0624@2|Bacteria,2G8AH@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS2_k127_2907279_3	926569.ANT_01250	6.154e-190	595.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WZS2_k127_2907279_6	926569.ANT_01260	6.198e-47	171.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS2_k127_2939295_9	926569.ANT_12120	3.733e-31	134.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1
WZS2_k127_2939295_1	926569.ANT_10880	3.199e-90	312.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF1906,PG_binding_1,Peptidase_M15_4
WZS2_k127_2939295_4	926569.ANT_08930	4.706e-67	242.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WZS2_k127_2939295_7	926569.ANT_08940	2.161e-40	161.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
WZS2_k127_2939295_0	926569.ANT_08950	5.468e-98	348.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
WZS2_k127_2939295_8	706587.Desti_3898	1.98e-39	153.0	COG4871@1|root,COG4871@2|Bacteria	706587.Desti_3898|-	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2939295_5	635013.TherJR_0469	3.453e-58	210.0	COG4232@1|root,COG4232@2|Bacteria,1V9UQ@1239|Firmicutes,24DK4@186801|Clostridia,262P8@186807|Peptococcaceae	186801|Clostridia	CO	cytochrome c biogenesis protein, transmembrane region	-	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WZS2_k127_2939295_16	1158292.JPOE01000002_gene3358	0.0001945	46.0	COG1651@1|root,COG1651@2|Bacteria,1NEFD@1224|Proteobacteria,2VKFR@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbG	-	-	ko:K03805	-	-	-	-	ko00000,ko03110	-	-	-	Thioredoxin_2
WZS2_k127_2939295_6	765420.OSCT_1613	3.442e-52	192.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WZS2_k127_2939295_11	880073.Calab_1937	1.793e-12	72.0	2DRJZ@1|root,33C4Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2939295_15	234267.Acid_7191	3.364e-05	50.0	COG2823@1|root,COG2823@2|Bacteria,3Y8DF@57723|Acidobacteria	57723|Acidobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
WZS2_k127_2939295_13	754035.Mesau_02957	1.625e-06	53.0	2E54V@1|root,32ZXS@2|Bacteria,1N6QG@1224|Proteobacteria,2UG8S@28211|Alphaproteobacteria,43M5M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_2939295_12	332101.JIBU02000023_gene4679	7.778e-12	78.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,36ECY@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WZS2_k127_2939295_2	1303518.CCALI_01463	1.749e-82	283.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_2939295_3	1173028.ANKO01000126_gene4112	7.612e-81	284.0	COG0577@1|root,COG0577@2|Bacteria,1G1W4@1117|Cyanobacteria,1H89H@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type antimicrobial peptide transport system, permease component	salY	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS2_k127_2949036_1	45351.EDO38308	4.786e-152	486.0	COG1012@1|root,KOG2450@2759|Eukaryota,38CQ7@33154|Opisthokonta,3BH9X@33208|Metazoa	33208|Metazoa	C	aldehyde dehydrogenase (NAD) activity	aldh16a1	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WZS2_k127_2949036_3	1169143.KB911034_gene1742	1.105e-132	432.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,2VP4F@28216|Betaproteobacteria,1K3EP@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WZS2_k127_2949036_9	1128421.JAGA01000001_gene2367	4.051e-08	63.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,DUF3471
WZS2_k127_2949036_5	926569.ANT_23190	2.105e-115	394.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WZS2_k127_2949036_2	926569.ANT_23180	3.218e-138	451.0	COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi	200795|Chloroflexi	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
WZS2_k127_2949036_0	926569.ANT_23160	1.042e-174	579.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi	200795|Chloroflexi	L	PFAM SMC domain protein	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
WZS2_k127_2949036_8	926569.ANT_29030	1.366e-23	102.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
WZS2_k127_2949036_7	1487953.JMKF01000064_gene4752	3.555e-65	234.0	COG0682@1|root,COG0682@2|Bacteria,1G23G@1117|Cyanobacteria	1117|Cyanobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WZS2_k127_2949036_4	321327.CYA_2481	1.503e-130	434.0	COG3119@1|root,COG3119@2|Bacteria,1G35S@1117|Cyanobacteria,1H28E@1129|Synechococcus	1117|Cyanobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
WZS2_k127_2949036_6	272123.Anacy_3746	3.307e-83	282.0	COG1230@1|root,COG1230@2|Bacteria,1G3AT@1117|Cyanobacteria,1HMIX@1161|Nostocales	1117|Cyanobacteria	P	TIGRFAM cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
WZS2_k127_2964337_10	926569.ANT_10000	7.774e-05	45.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
WZS2_k127_2964337_5	926569.ANT_09990	7.311e-69	236.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi	200795|Chloroflexi	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
WZS2_k127_2964337_0	926569.ANT_09980	0.0	1998.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WZS2_k127_2964337_4	926569.ANT_01460	8.167e-112	368.0	COG1159@1|root,COG1159@2|Bacteria,2G69C@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WZS2_k127_2964337_8	998088.B565_3711	5.24e-22	105.0	COG3714@1|root,COG3714@2|Bacteria,1PN0I@1224|Proteobacteria,1RNUV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	yhhN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	YhhN
WZS2_k127_2964337_2	926569.ANT_27030	2.431e-291	907.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
WZS2_k127_2964337_6	443143.GM18_3916	8.109e-44	170.0	COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
WZS2_k127_2964337_3	926569.ANT_07760	4.49e-133	429.0	COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WZS2_k127_2964337_7	926569.ANT_07750	2.015e-32	136.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WZS2_k127_2964337_1	926569.ANT_20890	5.347e-298	925.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WZS2_k127_2964337_9	926550.CLDAP_29370	2.903e-20	98.0	COG0354@1|root,COG0354@2|Bacteria,2G8ZM@200795|Chloroflexi	200795|Chloroflexi	S	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WZS2_k127_3014915_9	926569.ANT_19290	1.064e-59	215.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3014915_7	926569.ANT_19280	3.92e-94	315.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WZS2_k127_3014915_2	926569.ANT_13240	2.247e-189	597.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WZS2_k127_3014915_5	1121346.KB899814_gene1769	4.542e-131	426.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,26S0M@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WZS2_k127_3014915_4	926569.ANT_13260	3.736e-144	470.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
WZS2_k127_3014915_6	926569.ANT_13270	8.799e-124	403.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WZS2_k127_3014915_3	926569.ANT_13120	6.079e-179	578.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WZS2_k127_3014915_1	926569.ANT_13370	1.823e-221	694.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
WZS2_k127_3014915_8	926569.ANT_13360	9.33e-70	244.0	COG0584@1|root,COG0584@2|Bacteria,2G6YD@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WZS2_k127_3014915_11	263358.VAB18032_19720	2.002e-27	122.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4DB71@85008|Micromonosporales	201174|Actinobacteria	I	Coenzyme A transferase	catJ	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS2_k127_3014915_0	926569.ANT_13340	2.012e-241	777.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
WZS2_k127_3014915_10	926569.ANT_13330	5.256e-35	138.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS2_k127_3029722_2	926569.ANT_29680	3.827e-138	450.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS2_k127_3029722_0	926569.ANT_29670	7.141e-222	702.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS2_k127_3029722_5	926569.ANT_06070	3.461e-79	277.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WZS2_k127_3029722_6	316274.Haur_0217	1.542e-56	212.0	COG2114@1|root,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cyaH	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
WZS2_k127_3029722_4	1303518.CCALI_01780	6.363e-101	342.0	COG0153@1|root,COG0153@2|Bacteria	2|Bacteria	G	galactokinase activity	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WZS2_k127_3029722_3	926569.ANT_02010	6.708e-134	430.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS2_k127_3029722_7	867845.KI911784_gene1719	3.165e-33	139.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
WZS2_k127_3029722_1	926569.ANT_02020	1.305e-147	472.0	COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS2_k127_3069085_0	1123508.JH636452_gene7019	2.126e-113	369.0	COG0178@1|root,COG0178@2|Bacteria,2IYJN@203682|Planctomycetes	203682|Planctomycetes	L	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WZS2_k127_3069085_2	926569.ANT_22980	3.919e-40	161.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_3069085_1	926569.ANT_05580	1.292e-96	323.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
WZS2_k127_3069085_3	1382306.JNIM01000001_gene3976	3.334e-14	84.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS2_k127_3125872_6	1121430.JMLG01000007_gene2536	1.889e-72	252.0	COG3842@1|root,COG3842@2|Bacteria,1V5RM@1239|Firmicutes,24IMD@186801|Clostridia,261V9@186807|Peptococcaceae	186801|Clostridia	E	PFAM ABC transporter	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran,TOBE_2
WZS2_k127_3125872_4	671143.DAMO_1144	7.59e-79	269.0	COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria	2|Bacteria	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
WZS2_k127_3125872_3	1487923.DP73_01495	3.351e-89	303.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,2605W@186807|Peptococcaceae	186801|Clostridia	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WZS2_k127_3125872_9	635013.TherJR_0758	2.366e-51	196.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,2612F@186807|Peptococcaceae	186801|Clostridia	HP	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
WZS2_k127_3125872_5	335543.Sfum_0906	6.11e-77	260.0	COG1839@1|root,COG1839@2|Bacteria,1RBCB@1224|Proteobacteria,42S44@68525|delta/epsilon subdivisions,2WMAS@28221|Deltaproteobacteria,2MQHJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
WZS2_k127_3125872_10	926569.ANT_12610	6.322e-27	113.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WZS2_k127_3125872_0	926569.ANT_12590	0.0	1115.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS2_k127_3125872_8	926569.ANT_12580	1.848e-52	190.0	2EQH8@1|root,33I38@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3125872_2	926569.ANT_26810	9.444e-112	371.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria	2|Bacteria	K	Biogenesis protein	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K09792,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,Ferric_reduct,HMA
WZS2_k127_3125872_12	926569.ANT_26820	6.654e-16	79.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
WZS2_k127_3125872_1	926569.ANT_28140	2.507e-211	662.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WZS2_k127_3125872_15	349741.Amuc_1198	1.918e-07	55.0	COG1122@1|root,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	cbiO	-	-	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	M00245,M00246,M00581,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WZS2_k127_3125872_11	309801.trd_0071	2.692e-26	111.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi,27YE3@189775|Thermomicrobia	189775|Thermomicrobia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WZS2_k127_3125872_13	1340493.JNIF01000003_gene1493	7.659e-15	81.0	2E32R@1|root,32Y2Y@2|Bacteria,3Y5RV@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3125872_16	1298880.AUEV01000021_gene758	2.6e-05	53.0	COG3832@1|root,COG3832@2|Bacteria,2IHP6@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WZS2_k127_3125872_14	234267.Acid_4874	1.045e-12	74.0	2ED19@1|root,336Y7@2|Bacteria,3Y95N@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3125872_7	1380355.JNIJ01000012_gene1054	1.52e-53	200.0	COG2010@1|root,COG2010@2|Bacteria,1MXXQ@1224|Proteobacteria,2U38E@28211|Alphaproteobacteria,3JU2K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
WZS2_k127_3132160_2	203122.Sde_1088	6.389e-63	218.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,464H7@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF1260.b1637,iBWG_1329.BWG_1452,iECDH10B_1368.ECDH10B_1771,iECDH1ME8569_1439.ECDH1ME8569_1581,iECH74115_1262.ECH74115_2349,iECIAI39_1322.ECIAI39_1418,iECNA114_1301.ECNA114_1685,iECO103_1326.ECO103_1778,iECO111_1330.ECO111_2107,iECO26_1355.ECO26_2366,iECSE_1348.ECSE_1760,iECSF_1327.ECSF_1500,iECSP_1301.ECSP_2202,iECUMN_1333.ECUMN_1928,iECW_1372.ECW_m1805,iECs_1301.ECs2346,iEKO11_1354.EKO11_2137,iETEC_1333.ETEC_1672,iEcDH1_1363.EcDH1_2003,iEcE24377_1341.EcE24377A_1847,iEcHS_1320.EcHS_A1713,iEcSMS35_1347.EcSMS35_1562,iEcolC_1368.EcolC_1992,iJO1366.b1637,iSFV_1184.SFV_1654,iSF_1195.SF1662,iSSON_1240.SSON_1519,iSbBS512_1146.SbBS512_E1829,iUMNK88_1353.UMNK88_2097,iWFL_1372.ECW_m1805,iY75_1357.Y75_RS08585	S4,tRNA-synt_1b
WZS2_k127_3132160_0	1415778.JQMM01000001_gene415	1.171e-114	383.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1J4JE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	yebA	-	-	-	-	-	-	-	-	-	-	-	OapA,OapA_N,Peptidase_M23
WZS2_k127_3132160_1	1177179.A11A3_03144	1.346e-81	279.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1XH7D@135619|Oceanospirillales	135619|Oceanospirillales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
WZS2_k127_322026_7	926569.ANT_02650	7.453e-43	157.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi	2|Bacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS2_k127_322026_3	926569.ANT_02660	1.608e-104	347.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WZS2_k127_322026_4	926550.CLDAP_00860	1.418e-96	322.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_322026_8	1169144.KB910998_gene3092	1.416e-31	142.0	COG5002@1|root,COG5002@2|Bacteria,1V5Y3@1239|Firmicutes,4HHJ5@91061|Bacilli,1ZM3W@1386|Bacillus	91061|Bacilli	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	saeS	-	2.7.13.3	ko:K10681	ko02020,map02020	M00468	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS2_k127_322026_0	1173027.Mic7113_2806	3.294e-229	736.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria,1H9DA@1150|Oscillatoriales	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WZS2_k127_322026_6	192952.MM_1377	4.045e-50	199.0	COG5607@1|root,arCOG05139@2157|Archaea,2Y7EP@28890|Euryarchaeota,2NA8G@224756|Methanomicrobia	224756|Methanomicrobia	F	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
WZS2_k127_322026_2	383372.Rcas_0589	4.045e-110	367.0	COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like,PBP_like_2
WZS2_k127_322026_1	1128421.JAGA01000002_gene1716	9.941e-124	404.0	COG0573@1|root,COG0573@2|Bacteria,2NPS2@2323|unclassified Bacteria	2|Bacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS2_k127_322026_5	316274.Haur_3999	1.122e-70	249.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi,374ZR@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS2_k127_3223163_1	926569.ANT_31760	5.881e-85	287.0	COG1428@1|root,COG1428@2|Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
WZS2_k127_3223163_3	138119.DSY2637	2.89e-57	209.0	COG2267@1|root,COG2267@2|Bacteria,1V4GY@1239|Firmicutes,25EJZ@186801|Clostridia,261ST@186807|Peptococcaceae	186801|Clostridia	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WZS2_k127_3223163_0	926569.ANT_04130	3.157e-111	376.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
WZS2_k127_3223163_2	926569.ANT_04120	3.109e-77	264.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WZS2_k127_3223163_4	926569.ANT_04110	1.663e-45	170.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
WZS2_k127_3223163_6	926569.ANT_04100	1.489e-29	125.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS2_k127_3241081_2	357808.RoseRS_4511	4.126e-28	114.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
WZS2_k127_3241081_0	357808.RoseRS_4512	1.849e-104	349.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
WZS2_k127_3241081_3	370438.PTH_2273	8.213e-25	110.0	COG2172@1|root,COG2172@2|Bacteria,1VAPM@1239|Firmicutes,24J9J@186801|Clostridia	186801|Clostridia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS_2
WZS2_k127_3241081_4	251221.35213976	5.226e-07	60.0	COG2389@1|root,COG2389@2|Bacteria,1G6XV@1117|Cyanobacteria	1117|Cyanobacteria	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2227
WZS2_k127_3241081_1	76114.ebA864	3.804e-36	146.0	COG2199@1|root,COG3290@1|root,COG3290@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2WEG8@28216|Betaproteobacteria,2M03X@206389|Rhodocyclales	206389|Rhodocyclales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
WZS2_k127_3322163_3	1499967.BAYZ01000148_gene1741	8.394e-112	374.0	COG0477@1|root,COG0477@2|Bacteria,2NPX8@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WZS2_k127_3322163_5	765420.OSCT_2996	4.44e-55	205.0	COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,3764Y@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
WZS2_k127_3322163_7	335543.Sfum_4027	1.846e-49	200.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2MQDN@213462|Syntrophobacterales	1224|Proteobacteria	KT	Stage II sporulation	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2,sCache_2
WZS2_k127_3322163_0	926569.ANT_01520	1.446e-180	571.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WZS2_k127_3322163_4	926569.ANT_23030	7.563e-109	367.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
WZS2_k127_3322163_2	926569.ANT_23020	1.624e-150	499.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
WZS2_k127_3322163_1	1382306.JNIM01000001_gene2616	2.408e-159	521.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS2_k127_3322163_6	479434.Sthe_1188	7.554e-53	190.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,27Z0B@189775|Thermomicrobia	189775|Thermomicrobia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS2_k127_3333324_5	926569.ANT_29010	4.921e-10	60.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WZS2_k127_3333324_2	926569.ANT_29020	2.465e-29	123.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WZS2_k127_3333324_1	926569.ANT_02860	1.975e-101	344.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
WZS2_k127_3333324_0	926569.ANT_02850	3.364e-193	613.0	COG1236@1|root,COG1236@2|Bacteria,2G62G@200795|Chloroflexi	200795|Chloroflexi	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
WZS2_k127_3333324_3	35754.JNYJ01000001_gene7243	8.003e-22	100.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria,4DJZN@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3333324_4	331869.BAL199_27206	1.804e-10	61.0	COG0412@1|root,COG0412@2|Bacteria,1R9JT@1224|Proteobacteria,2U4J1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
WZS2_k127_3481061_4	566466.NOR53_553	1.686e-09	68.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1P8N9@1224|Proteobacteria,1S2A5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3481061_0	383372.Rcas_1634	3.264e-202	641.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi,374YV@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WZS2_k127_3481061_3	383372.Rcas_1633	2.579e-127	416.0	COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi,374T2@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS2_k127_3481061_1	383372.Rcas_1632	1.403e-133	436.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi,375FD@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS2_k127_3481061_2	357808.RoseRS_1320	3.054e-130	421.0	COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi,375H7@32061|Chloroflexia	32061|Chloroflexia	M	PFAM basic membrane lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WZS2_k127_3487341_8	338969.Rfer_0358	3.461e-47	173.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_3487341_5	864051.BurJ1DRAFT_3878	1.978e-69	250.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria	1224|Proteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
WZS2_k127_3487341_9	768706.Desor_3266	8.766e-37	157.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,260T5@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
WZS2_k127_3487341_6	1382306.JNIM01000001_gene1045	3.001e-59	213.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_3487341_4	338969.Rfer_0357	1.065e-77	263.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,4ABCM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
WZS2_k127_3487341_0	1521187.JPIM01000063_gene2480	1.537e-160	532.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WZS2_k127_3487341_10	357808.RoseRS_2721	1.677e-22	104.0	COG0748@1|root,COG0748@2|Bacteria,2GB8D@200795|Chloroflexi,377JG@32061|Chloroflexia	32061|Chloroflexia	P	PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	Pyrid_oxidase_2
WZS2_k127_3487341_7	1174528.JH992898_gene2575	1.51e-51	196.0	COG2334@1|root,COG2334@2|Bacteria,1G3HF@1117|Cyanobacteria	1117|Cyanobacteria	S	homoserine kinase type II (Protein kinase fold)	-	-	-	-	-	-	-	-	-	-	-	-	APH
WZS2_k127_3487341_1	926569.ANT_08170	8.634e-122	403.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS2_k127_3487341_2	926569.ANT_08160	1.538e-118	394.0	COG0842@1|root,COG0842@2|Bacteria,2G774@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS2_k127_3487341_3	926569.ANT_08150	5.203e-93	310.0	COG1131@1|root,COG1131@2|Bacteria,2G5WA@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_3525219_2	357808.RoseRS_1205	5.694e-49	191.0	COG1572@1|root,COG1572@2|Bacteria,2G7MU@200795|Chloroflexi,374XB@32061|Chloroflexia	32061|Chloroflexia	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
WZS2_k127_3525219_6	1158607.UAU_00402	1.609e-09	66.0	COG0681@1|root,COG0681@2|Bacteria,1VI11@1239|Firmicutes,4IR2F@91061|Bacilli,4B2AU@81852|Enterococcaceae	91061|Bacilli	U	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
WZS2_k127_3525219_3	565045.NOR51B_2671	1.818e-42	178.0	COG1572@1|root,COG1572@2|Bacteria,1N1AP@1224|Proteobacteria,1SQWS@1236|Gammaproteobacteria,1JBJG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
WZS2_k127_3525219_1	1219031.BBJR01000054_gene2148	1.068e-56	214.0	COG1571@1|root,COG1571@2|Bacteria,1QVS8@1224|Proteobacteria,2VI63@28216|Betaproteobacteria,4ACFP@80864|Comamonadaceae	28216|Betaproteobacteria	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3525219_4	1121015.N789_11825	3.264e-18	96.0	COG1571@1|root,COG1571@2|Bacteria,1QVS8@1224|Proteobacteria,1T2IQ@1236|Gammaproteobacteria,1X9DX@135614|Xanthomonadales	135614|Xanthomonadales	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3525219_0	926550.CLDAP_12700	1.199e-179	582.0	COG0326@1|root,COG0326@2|Bacteria,2G60B@200795|Chloroflexi	200795|Chloroflexi	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
WZS2_k127_3525219_7	1205680.CAKO01000002_gene2120	5.981e-08	64.0	COG1493@1|root,COG1493@2|Bacteria,1NCNM@1224|Proteobacteria,2UIMS@28211|Alphaproteobacteria,2JUA0@204441|Rhodospirillales	204441|Rhodospirillales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3525219_8	1121939.L861_02680	8.721e-06	57.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.3.6,6.3.5.4	ko:K01953,ko:K18316	ko00250,ko00332,ko01100,ko01110,ko01130,ko02024,map00250,map00332,map01100,map01110,map01130,map02024	M00675	R00578,R10556	RC00010,RC03195	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Asn_synthase,DUF1933,GATase_7
WZS2_k127_3533750_0	1265505.ATUG01000001_gene3075	2.081e-150	484.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS2_k127_3533750_3	211114.JOEF01000008_gene1310	1.59e-13	83.0	COG0454@1|root,COG0456@2|Bacteria,2GJ68@201174|Actinobacteria,4E1Y7@85010|Pseudonocardiales	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_3533750_1	926569.ANT_12210	8.722e-45	178.0	COG1653@1|root,COG1653@2|Bacteria,2G7EJ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
WZS2_k127_3533750_2	194439.CT2140	1.512e-42	160.0	COG0824@1|root,COG0824@2|Bacteria,1FF3Z@1090|Chlorobi	1090|Chlorobi	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
WZS2_k127_3575130_4	1227739.Hsw_1503	3.441e-07	56.0	COG2819@1|root,COG2819@2|Bacteria,4PMBF@976|Bacteroidetes,47XC5@768503|Cytophagia	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
WZS2_k127_3575130_1	765910.MARPU_00280	1.024e-106	361.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1WZAK@135613|Chromatiales	135613|Chromatiales	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
WZS2_k127_3575130_3	1121405.dsmv_0822	2.151e-13	78.0	COG0517@1|root,COG0517@2|Bacteria,1QUKQ@1224|Proteobacteria,42TPD@68525|delta/epsilon subdivisions,2WQQ5@28221|Deltaproteobacteria,2MK07@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WZS2_k127_3575130_5	1449976.KALB_6098	0.0001728	53.0	COG3271@1|root,COG3271@2|Bacteria,2GN8Z@201174|Actinobacteria,4EATI@85010|Pseudonocardiales	201174|Actinobacteria	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C70
WZS2_k127_3575130_0	1519464.HY22_14040	2.61e-156	507.0	COG2270@1|root,COG2270@2|Bacteria,1FDCC@1090|Chlorobi	1090|Chlorobi	S	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WZS2_k127_3575130_2	1121129.KB903360_gene3049	3.584e-22	100.0	COG2227@1|root,COG2227@2|Bacteria,4PHSI@976|Bacteroidetes,2FQX4@200643|Bacteroidia,230QA@171551|Porphyromonadaceae	976|Bacteroidetes	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS2_k127_3584493_4	926569.ANT_16010	9.854e-81	274.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
WZS2_k127_3584493_5	926569.ANT_16020	3.571e-48	177.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi	200795|Chloroflexi	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WZS2_k127_3584493_7	656519.Halsa_1367	9.883e-19	88.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3WAV0@53433|Halanaerobiales	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
WZS2_k127_3584493_6	926569.ANT_16040	1.44e-40	153.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WZS2_k127_3584493_0	926569.ANT_16050	5.161e-203	640.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WZS2_k127_3584493_3	926569.ANT_22980	1.471e-84	289.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_3584493_1	926569.ANT_22990	1.741e-161	520.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015,SusD-like,SusD-like_2
WZS2_k127_3584493_2	926550.CLDAP_35270	4.497e-108	365.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS2_k127_3608288_5	926569.ANT_28350	9.567e-35	136.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Stage V sporulation protein S	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
WZS2_k127_3608288_1	926569.ANT_30540	5.224e-113	378.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3608288_7	926569.ANT_11380	4.078e-24	108.0	COG1716@1|root,COG1716@2|Bacteria,2G759@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
WZS2_k127_3608288_8	326427.Cagg_1633	2.69e-17	92.0	COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
WZS2_k127_3608288_6	926550.CLDAP_38690	1.099e-27	120.0	COG1371@1|root,COG1371@2|Bacteria,2G7BQ@200795|Chloroflexi	200795|Chloroflexi	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
WZS2_k127_3608288_0	926569.ANT_11350	5.656e-237	741.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
WZS2_k127_3608288_3	926569.ANT_29460	5.416e-60	210.0	COG0757@1|root,COG0757@2|Bacteria,2G70K@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
WZS2_k127_3608288_2	926550.CLDAP_07310	6.408e-105	360.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
WZS2_k127_3608288_4	926569.ANT_01910	6.684e-51	182.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
WZS2_k127_3611346_1	926550.CLDAP_11040	1.057e-162	524.0	COG3889@1|root,COG3889@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WZS2_k127_3611346_5	926550.CLDAP_11030	4.796e-140	455.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WZS2_k127_3611346_3	926550.CLDAP_11020	3.069e-150	488.0	COG1173@1|root,COG1173@2|Bacteria,2G841@200795|Chloroflexi	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
WZS2_k127_3611346_4	926550.CLDAP_11010	4.599e-147	471.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WZS2_k127_3611346_2	926550.CLDAP_11000	6.268e-154	493.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS2_k127_3611346_0	926569.ANT_01400	1.866e-168	534.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WZS2_k127_3611346_6	926569.ANT_01410	2.46e-120	390.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS2_k127_3648668_0	926569.ANT_15470	6.091e-276	863.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi	200795|Chloroflexi	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WZS2_k127_3648668_3	552811.Dehly_1213	2.691e-42	173.0	COG2211@1|root,COG2211@2|Bacteria,2G8SN@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3648668_2	1128421.JAGA01000002_gene1336	2.316e-61	225.0	COG2514@1|root,COG2514@2|Bacteria,2NRH9@2323|unclassified Bacteria	2|Bacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	CppA_C,Glyoxalase
WZS2_k127_3648668_4	1380390.JIAT01000002_gene6019	5.983e-31	129.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CQ75@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WZS2_k127_3648668_1	926569.ANT_13200	3.138e-104	344.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
WZS2_k127_3660310_12	1279009.ADICEAN_03394	1.12e-15	78.0	COG2062@1|root,COG2062@2|Bacteria,4NQFM@976|Bacteroidetes,47R7I@768503|Cytophagia	976|Bacteroidetes	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WZS2_k127_3660310_7	1121946.AUAX01000002_gene153	1.863e-64	227.0	COG0602@1|root,COG0602@2|Bacteria,2H0HA@201174|Actinobacteria,4DDSR@85008|Micromonosporales	201174|Actinobacteria	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WZS2_k127_3660310_13	926569.ANT_19130	4.536e-15	88.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	rickA	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_11,AAA_12,Apolipoprotein
WZS2_k127_3660310_0	926569.ANT_19140	5.505e-178	591.0	COG0464@1|root,COG0464@2|Bacteria,2G8T4@200795|Chloroflexi	200795|Chloroflexi	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
WZS2_k127_3660310_9	926550.CLDAP_35390	8.948e-35	137.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
WZS2_k127_3660310_3	926569.ANT_25160	2.562e-140	457.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS2_k127_3660310_1	926569.ANT_25170	2.8e-172	550.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS2_k127_3660310_10	926569.ANT_25180	3.512e-33	137.0	2FF2N@1|root,3470Y@2|Bacteria,2G9SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3660310_2	926569.ANT_25190	6.399e-150	486.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
WZS2_k127_3660310_6	1382306.JNIM01000001_gene3438	2.229e-79	278.0	COG2355@1|root,COG2355@2|Bacteria,2G6FQ@200795|Chloroflexi	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
WZS2_k127_3660310_4	926569.ANT_19050	1.94e-123	406.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,2G62P@200795|Chloroflexi	200795|Chloroflexi	L	HhH-GPD family	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
WZS2_k127_3660310_11	926569.ANT_19040	2.136e-32	130.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3660310_5	926569.ANT_19030	1.385e-96	320.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
WZS2_k127_3661899_3	926550.CLDAP_27450	1.385e-56	201.0	COG2183@1|root,COG2183@2|Bacteria,2G66S@200795|Chloroflexi	200795|Chloroflexi	K	Tex-like protein N-terminal domain	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
WZS2_k127_3661899_0	926550.CLDAP_15290	4.798e-118	390.0	COG0451@1|root,COG0451@2|Bacteria,2G7TT@200795|Chloroflexi	200795|Chloroflexi	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WZS2_k127_3661899_2	1499967.BAYZ01000008_gene5415	6.899e-57	205.0	COG3551@1|root,COG3551@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_trans_1_4,Glycos_transf_2,TPR_19
WZS2_k127_3661899_4	765420.OSCT_2895	1.525e-27	117.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
WZS2_k127_3661899_1	1128421.JAGA01000003_gene3678	6.227e-74	263.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
WZS2_k127_3664934_3	1128421.JAGA01000002_gene172	1.264e-17	88.0	COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria	2|Bacteria	I	Phosphate acyltransferases	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,Cytidylate_kin
WZS2_k127_3664934_2	485913.Krac_4380	3.584e-26	117.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WZS2_k127_3664934_0	926569.ANT_10850	1.259e-210	699.0	COG2203@1|root,COG2770@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636,ko:K07642	ko02020,map02020	M00434,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
WZS2_k127_3664934_1	926569.ANT_10860	3.611e-99	325.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WZS2_k127_3678213_7	1521187.JPIM01000023_gene772	4.004e-60	217.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS2_k127_3678213_2	383372.Rcas_0076	1.466e-170	560.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,3756Y@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
WZS2_k127_3678213_5	1448860.BBJO01000014_gene1200	8.052e-81	299.0	COG1501@1|root,arCOG03663@2157|Archaea,2XV49@28890|Euryarchaeota,23V0G@183963|Halobacteria	183963|Halobacteria	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
WZS2_k127_3678213_6	926569.ANT_12020	1.328e-60	216.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
WZS2_k127_3678213_13	926550.CLDAP_20590	1.925e-14	76.0	COG5660@1|root,COG5660@2|Bacteria,2G7CH@200795|Chloroflexi	200795|Chloroflexi	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WZS2_k127_3678213_10	383372.Rcas_0861	5.428e-30	126.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WZS2_k127_3678213_9	926569.ANT_12060	3.137e-45	168.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
WZS2_k127_3678213_11	545264.KB898755_gene2826	4.702e-24	106.0	COG0607@1|root,COG0607@2|Bacteria,1N70J@1224|Proteobacteria,1SE5K@1236|Gammaproteobacteria,1X1AU@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WZS2_k127_3678213_0	926569.ANT_09360	7.081e-212	665.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
WZS2_k127_3678213_4	926569.ANT_09370	5.476e-95	324.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
WZS2_k127_3678213_8	926569.ANT_30350	4.23e-46	187.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_3678213_1	926569.ANT_30340	1.173e-205	657.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WZS2_k127_3866652_5	867845.KI911784_gene1921	1.328e-06	51.0	COG2270@1|root,COG2270@2|Bacteria,2G8AF@200795|Chloroflexi,3771A@32061|Chloroflexia	32061|Chloroflexia	S	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_3866652_1	926569.ANT_23120	6.869e-92	314.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
WZS2_k127_3866652_2	926569.ANT_14100	5.223e-79	280.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS2_k127_3866652_0	926569.ANT_19080	1.06e-189	602.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
WZS2_k127_3866652_3	926569.ANT_30670	2.237e-52	186.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WZS2_k127_3867572_4	926569.ANT_22770	2.631e-17	85.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
WZS2_k127_3867572_1	1521187.JPIM01000001_gene834	4.89e-62	226.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_3867572_5	459349.CLOAM0161	6.405e-11	64.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_3867572_3	926569.ANT_25610	1.83e-17	94.0	COG4254@1|root,COG4254@2|Bacteria,2G9J2@200795|Chloroflexi	200795|Chloroflexi	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
WZS2_k127_3867572_0	383372.Rcas_4054	4.208e-149	484.0	COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_3867572_2	926569.ANT_03400	8.382e-60	216.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_3980027_2	794903.OPIT5_11650	3.718e-95	323.0	COG2081@1|root,COG2081@2|Bacteria,46TWE@74201|Verrucomicrobia,3K7FU@414999|Opitutae	414999|Opitutae	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WZS2_k127_3980027_0	926550.CLDAP_22540	1.702e-129	424.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
WZS2_k127_3980027_1	324602.Caur_0607	6.251e-126	424.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
WZS2_k127_3980027_3	1337936.IJ00_05685	1.168e-63	231.0	COG0253@1|root,COG0253@2|Bacteria,1GBIU@1117|Cyanobacteria,1HMMZ@1161|Nostocales	1117|Cyanobacteria	J	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	-	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
WZS2_k127_4123311_6	1121335.Clst_1469	2.097e-18	88.0	COG1451@1|root,COG1451@2|Bacteria,1VPXB@1239|Firmicutes,24VRE@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WZS2_k127_4123311_4	1121335.Clst_1470	2.032e-31	125.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,248A6@186801|Clostridia,3WGWH@541000|Ruminococcaceae	186801|Clostridia	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
WZS2_k127_4123311_3	326427.Cagg_2114	1.257e-71	262.0	COG0823@1|root,COG3693@1|root,COG0823@2|Bacteria,COG3693@2|Bacteria,2GA75@200795|Chloroflexi,37735@32061|Chloroflexia	32061|Chloroflexia	U	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_4123311_2	660470.Theba_0855	1.025e-83	304.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF4118,GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
WZS2_k127_4123311_5	926569.ANT_02090	4.198e-29	124.0	29Z2W@1|root,30M0E@2|Bacteria,2G9IN@200795|Chloroflexi	200795|Chloroflexi	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
WZS2_k127_4123311_0	926569.ANT_04770	2.552e-219	718.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
WZS2_k127_4123311_1	1094980.Mpsy_2980	1.534e-98	364.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,arCOG02348@1|root,arCOG02352@1|root,arCOG02360@1|root,arCOG02376@1|root,arCOG04001@1|root,arCOG02348@2157|Archaea,arCOG02352@2157|Archaea,arCOG02357@2157|Archaea,arCOG02360@2157|Archaea,arCOG02376@2157|Archaea,arCOG02591@2157|Archaea,arCOG02595@2157|Archaea,arCOG04001@2157|Archaea,2Y82D@28890|Euryarchaeota,2NBNN@224756|Methanomicrobia	2157|Archaea	T	Histidine Phosphotransfer domain	-	-	2.7.7.65	ko:K02488,ko:K11443	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	BAT,GAF,GAF_2,GAF_3,HATPase_c,HTH_10,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
WZS2_k127_4146242_13	926569.ANT_22870	4.666e-18	84.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WZS2_k127_4146242_3	926569.ANT_27080	1.989e-102	341.0	29XJE@1|root,30JAE@2|Bacteria,2G9SD@200795|Chloroflexi	200795|Chloroflexi	S	Streptomycin adenylyltransferase	-	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
WZS2_k127_4146242_4	926569.ANT_20830	9.607e-101	339.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
WZS2_k127_4146242_11	604331.AUHY01000042_gene2025	3.526e-31	130.0	COG0406@1|root,COG0406@2|Bacteria,1WMWI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WZS2_k127_4146242_10	604331.AUHY01000042_gene2025	7.499e-37	147.0	COG0406@1|root,COG0406@2|Bacteria,1WMWI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WZS2_k127_4146242_0	926550.CLDAP_31520	3.459e-166	533.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi	200795|Chloroflexi	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WZS2_k127_4146242_1	926569.ANT_20820	2.598e-118	387.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi	200795|Chloroflexi	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WZS2_k127_4146242_8	489825.LYNGBM3L_35430	4.07e-41	159.0	COG1051@1|root,COG1051@2|Bacteria,1G72H@1117|Cyanobacteria,1HBT6@1150|Oscillatoriales	1117|Cyanobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS2_k127_4146242_2	926569.ANT_07850	7.533e-110	362.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WZS2_k127_4146242_12	1056820.KB900629_gene1601	1.462e-25	110.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,1S929@1236|Gammaproteobacteria,2PNUS@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Translation initiation factor SUI1	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
WZS2_k127_4146242_9	525904.Tter_0400	3.209e-37	149.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
WZS2_k127_4146242_5	926569.ANT_19170	1.511e-70	261.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	ko:K04066,ko:K07037,ko:K17266	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400,ko04147	-	-	-	Band_7
WZS2_k127_4146242_6	1341151.ASZU01000009_gene898	1.016e-64	233.0	COG0464@1|root,COG0464@2|Bacteria,1TPQZ@1239|Firmicutes,4HCQK@91061|Bacilli,27AZH@186824|Thermoactinomycetaceae	91061|Bacilli	O	Holliday junction DNA helicase ruvB N-terminus	spoVK	-	-	ko:K06413	-	-	-	-	ko00000	-	-	-	AAA
WZS2_k127_421550_4	926569.ANT_18420	2.073e-70	259.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DNA_alkylation,GUN4,HEAT_2,Mrr_cat,NACHT
WZS2_k127_421550_9	497964.CfE428DRAFT_3040	9.457e-12	70.0	COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
WZS2_k127_421550_8	926569.ANT_18440	9.096e-18	85.0	COG0762@1|root,COG0762@2|Bacteria	2|Bacteria	D	integral membrane protein	yggT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
WZS2_k127_421550_5	926569.ANT_18450	4.843e-64	228.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi	200795|Chloroflexi	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WZS2_k127_421550_3	926569.ANT_18460	7.853e-72	254.0	COG1496@1|root,COG1496@2|Bacteria,2G6N5@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WZS2_k127_421550_2	926569.ANT_18470	1.766e-74	263.0	COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WZS2_k127_421550_6	926569.ANT_18480	2.673e-39	154.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi	200795|Chloroflexi	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WZS2_k127_421550_0	926569.ANT_18490	2.884e-98	325.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WZS2_k127_421550_1	926569.ANT_18500	9.322e-98	331.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
WZS2_k127_421550_7	926569.ANT_12600	1.281e-18	87.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
WZS2_k127_4244939_0	765420.OSCT_0207	7.884e-225	710.0	COG0747@1|root,COG0747@2|Bacteria,2G85H@200795|Chloroflexi,3773I@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WZS2_k127_4244939_1	311402.Avi_5350	7.834e-132	429.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,4BBR1@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02033,ko:K12369	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WZS2_k127_4244939_2	311402.Avi_5351	3.443e-128	419.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VETJ@28211|Alphaproteobacteria,4B73C@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	dppC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WZS2_k127_4244939_4	351607.Acel_2051	5.834e-05	50.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,Hemerythrin,MCPsignal,dCache_1
WZS2_k127_4270736_3	333138.LQ50_25390	1.491e-14	79.0	COG1309@1|root,COG1309@2|Bacteria,1V7QU@1239|Firmicutes,4HJIT@91061|Bacilli,1ZGD2@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	yxaF	-	-	ko:K18939	-	M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_N
WZS2_k127_4270736_1	930171.Asphe3_21200	2.232e-48	185.0	2FGCJ@1|root,3488S@2|Bacteria,2H97A@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_4270736_0	931276.Cspa_c21210	2.788e-83	284.0	COG4221@1|root,COG4221@2|Bacteria,1TQDY@1239|Firmicutes,24M3R@186801|Clostridia,36WEC@31979|Clostridiaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WZS2_k127_4270736_2	316274.Haur_1699	4.883e-44	166.0	COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi,377J0@32061|Chloroflexia	32061|Chloroflexia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
WZS2_k127_4282665_4	661478.OP10G_0619	2.992e-26	120.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
WZS2_k127_4282665_1	886293.Sinac_7570	4.44e-156	506.0	COG2242@1|root,COG2242@2|Bacteria,2J25Y@203682|Planctomycetes	203682|Planctomycetes	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_4282665_0	926569.ANT_28990	8.994e-182	577.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WZS2_k127_4282665_5	114615.BRADO5974	5.635e-14	84.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,3JT48@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
WZS2_k127_4282665_2	926569.ANT_28850	4.175e-58	203.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
WZS2_k127_4282665_3	1041930.Mtc_1580	4.065e-53	204.0	COG0477@1|root,arCOG00132@2157|Archaea,2XYHV@28890|Euryarchaeota,2NAK2@224756|Methanomicrobia	224756|Methanomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_4282665_6	1120950.KB892754_gene6038	5.042e-13	76.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
WZS2_k127_4471025_3	1120950.KB892757_gene6616	1.669e-48	179.0	COG0637@1|root,COG0637@2|Bacteria,2IQD3@201174|Actinobacteria,4DRPS@85009|Propionibacteriales	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WZS2_k127_4471025_2	1122223.KB890687_gene2436	1.024e-77	264.0	COG0225@1|root,COG0225@2|Bacteria,1WK2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WZS2_k127_4471025_4	748449.Halha_2525	1.776e-40	154.0	COG2731@1|root,COG2731@2|Bacteria,1VCI9@1239|Firmicutes,24QNC@186801|Clostridia	186801|Clostridia	G	YhcH YjgK YiaL family	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
WZS2_k127_4471025_1	1191523.MROS_0728	2.848e-95	322.0	2EY85@1|root,33RGN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_4471025_0	1191523.MROS_0727	0.0	1476.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SusD-like_3,SusD_RagB
WZS2_k127_4486601_14	926569.ANT_23430	3.046e-30	121.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WZS2_k127_4486601_13	926569.ANT_23440	5.524e-39	160.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	6.3.2.4	ko:K01921,ko:K03589	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
WZS2_k127_4486601_2	926569.ANT_23450	1.963e-178	567.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WZS2_k127_4486601_3	926569.ANT_23460	9.923e-168	535.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WZS2_k127_4486601_9	926569.ANT_01450	2.664e-73	249.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
WZS2_k127_4486601_16	1121013.P873_12300	5.465e-07	61.0	arCOG08211@1|root,2ZBM3@2|Bacteria,1RIRV@1224|Proteobacteria,1SFXN@1236|Gammaproteobacteria,1X59H@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_4486601_0	926569.ANT_28860	3.14e-287	907.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi	200795|Chloroflexi	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WZS2_k127_4486601_7	479434.Sthe_1848	1.62e-112	377.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi,27YYU@189775|Thermomicrobia	189775|Thermomicrobia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WZS2_k127_4486601_8	926569.ANT_07440	4.445e-89	301.0	COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
WZS2_k127_4486601_15	502025.Hoch_0529	1.863e-14	74.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
WZS2_k127_4486601_11	926569.ANT_09390	1.259e-55	198.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi	200795|Chloroflexi	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WZS2_k127_4486601_10	926569.ANT_17610	1.916e-65	229.0	COG1611@1|root,COG1611@2|Bacteria,2G6P1@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
WZS2_k127_4486601_6	926569.ANT_25030	6.403e-114	374.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WZS2_k127_4486601_5	1121324.CLIT_11c00880	8.708e-121	399.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25QX8@186804|Peptostreptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WZS2_k127_4486601_1	765420.OSCT_0149	5.068e-270	847.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi,3755N@32061|Chloroflexia	32061|Chloroflexia	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WZS2_k127_4486601_12	926569.ANT_25060	1.641e-43	165.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
WZS2_k127_4486601_4	926569.ANT_25070	1.418e-121	399.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
WZS2_k127_456314_4	926569.ANT_22890	1.571e-36	141.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
WZS2_k127_456314_1	926569.ANT_13990	1.064e-103	346.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WZS2_k127_456314_0	926569.ANT_13980	4.075e-115	376.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WZS2_k127_456314_2	926569.ANT_13970	1.237e-86	295.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WZS2_k127_456314_3	926569.ANT_13960	5.205e-60	215.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS2_k127_4574177_0	1128421.JAGA01000001_gene2449	1.334e-188	610.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2,TOBE_3
WZS2_k127_4574177_2	1128421.JAGA01000001_gene2451	8.123e-95	322.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02046,ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iPC815.YPO3013	BPD_transp_1
WZS2_k127_4574177_3	316274.Haur_0257	7.662e-89	301.0	COG4208@1|root,COG4208@2|Bacteria	2|Bacteria	P	ATPase-coupled sulfate transmembrane transporter activity	cysW	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02046,ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	iPC815.YPO3013	BPD_transp_1
WZS2_k127_4574177_4	1185653.A1A1_07242	1.076e-19	98.0	COG0560@1|root,COG0560@2|Bacteria,1V1P2@1239|Firmicutes,4HGRG@91061|Bacilli,26F08@186818|Planococcaceae	91061|Bacilli	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
WZS2_k127_4574177_1	867845.KI911784_gene770	5.667e-147	477.0	COG1472@1|root,COG1472@2|Bacteria,2G639@200795|Chloroflexi,374XN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
WZS2_k127_4576430_6	1306174.JODP01000002_gene5612	6.384e-18	89.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
WZS2_k127_4576430_4	926550.CLDAP_04820	1.511e-24	109.0	COG1051@1|root,COG1051@2|Bacteria,2G9U6@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS2_k127_4576430_2	525904.Tter_1226	2.59e-105	352.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2
WZS2_k127_4576430_1	765420.OSCT_2981	1.083e-119	392.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,374VR@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
WZS2_k127_4576430_0	639282.DEFDS_0814	3.187e-162	522.0	COG0372@1|root,COG0372@2|Bacteria,2GEZB@200930|Deferribacteres	200930|Deferribacteres	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WZS2_k127_4576430_5	497964.CfE428DRAFT_3727	2.11e-19	95.0	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
WZS2_k127_4576430_3	309801.trd_0274	2.022e-64	235.0	COG5438@1|root,COG5438@2|Bacteria	2|Bacteria	S	YibE/F-like protein	yibE	-	-	-	-	-	-	-	-	-	-	-	YibE_F
WZS2_k127_4576430_7	926569.ANT_17240	7.049e-06	49.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
WZS2_k127_4583884_0	485913.Krac_2812	8.015e-88	298.0	COG1131@1|root,COG1131@2|Bacteria,2G6E6@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG1131 ABC-type multidrug transport system ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WZS2_k127_4583884_2	298653.Franean1_3992	1.169e-12	79.0	COG5662@1|root,COG5662@2|Bacteria,2IQGX@201174|Actinobacteria	201174|Actinobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
WZS2_k127_4583884_1	1394178.AWOO02000005_gene3632	7.845e-29	123.0	COG1595@1|root,COG1595@2|Bacteria,2IJ11@201174|Actinobacteria,4EPIJ@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WZS2_k127_4628033_4	706587.Desti_2993	1.042e-55	197.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
WZS2_k127_4628033_2	1197130.BAFM01000016_gene2564	4.471e-100	337.0	COG0438@1|root,arCOG01407@2157|Archaea,2Y8BB@28890|Euryarchaeota,24180@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WZS2_k127_4628033_3	706587.Desti_2991	6.394e-77	268.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,RrnaAD
WZS2_k127_4628033_5	926569.ANT_09790	2.567e-36	145.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi	200795|Chloroflexi	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WZS2_k127_4628033_1	926569.ANT_09800	1.678e-125	408.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS2_k127_4628033_0	926569.ANT_09810	2.312e-137	445.0	COG2008@1|root,COG2008@2|Bacteria,2G5XG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	gly1	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WZS2_k127_4628033_8	195522.BD01_0961	8.475e-12	77.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y7P0@28890|Euryarchaeota,245AH@183968|Thermococci	183968|Thermococci	Q	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS2_k127_4628033_6	926566.Terro_1883	1.448e-31	139.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83,6.2.1.30	ko:K00721,ko:K01912,ko:K08301	ko00360,ko00510,ko01100,ko01120,ko05111,map00360,map00510,map01100,map01120,map05111	-	R01009,R02539	RC00004,RC00005,RC00014	ko00000,ko00001,ko01000,ko01003,ko03009,ko03019	-	GT2	-	Glycos_transf_2
WZS2_k127_4628033_7	1123508.JH636442_gene4122	1.615e-19	102.0	2EPSC@1|root,33HCV@2|Bacteria,2J2Q4@203682|Planctomycetes	203682|Planctomycetes	S	Pfam:DUF2029	-	-	-	-	-	-	-	-	-	-	-	-	GT87
WZS2_k127_4647351_9	926569.ANT_05350	3.616e-51	190.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
WZS2_k127_4647351_2	926569.ANT_11910	5.518e-84	284.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
WZS2_k127_4647351_5	926569.ANT_11900	5.867e-69	246.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi	200795|Chloroflexi	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
WZS2_k127_4647351_3	926569.ANT_30070	8.146e-84	284.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WZS2_k127_4647351_8	324602.Caur_2528	7.405e-54	194.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
WZS2_k127_4647351_1	926569.ANT_31560	5.011e-142	462.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WZS2_k127_4647351_6	926569.ANT_31550	3.888e-65	226.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WZS2_k127_4647351_7	926569.ANT_30100	2.315e-60	229.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
WZS2_k127_4647351_0	926569.ANT_31260	9.024e-238	743.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WZS2_k127_4647351_4	926569.ANT_00400	1.039e-74	261.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_465213_32	926569.ANT_16910	1.796e-08	60.0	COG1508@1|root,COG1508@2|Bacteria,2G5VM@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WZS2_k127_465213_15	926569.ANT_04210	3.468e-107	357.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
WZS2_k127_465213_17	926569.ANT_23650	5.472e-106	375.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
WZS2_k127_465213_4	926569.ANT_23640	8.405e-188	602.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
WZS2_k127_465213_16	768671.ThimaDRAFT_1778	2.774e-106	354.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1X0CX@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.25	ko:K17950	ko00270,map00270	-	R07634	RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
WZS2_k127_465213_11	926569.ANT_22600	4.515e-134	439.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WZS2_k127_465213_14	926569.ANT_22610	2.356e-117	387.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WZS2_k127_465213_2	926569.ANT_22620	1.792e-227	722.0	COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi	200795|Chloroflexi	GM	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
WZS2_k127_465213_7	926569.ANT_22630	1.607e-148	484.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G6DJ@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WZS2_k127_465213_19	926569.ANT_22650	8.962e-80	285.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS2_k127_465213_21	926569.ANT_22660	4.596e-72	252.0	COG0745@1|root,COG0745@2|Bacteria,2G8CC@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_465213_24	1128398.Curi_c19740	8.042e-41	154.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,269BT@186813|unclassified Clostridiales	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WZS2_k127_465213_18	926569.ANT_10690	2.027e-99	328.0	COG1402@1|root,COG1402@2|Bacteria,2G7B0@200795|Chloroflexi	200795|Chloroflexi	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
WZS2_k127_465213_8	1279009.ADICEAN_00534	2.388e-148	487.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	isp	-	-	ko:K13275	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
WZS2_k127_465213_25	926569.ANT_10410	9.578e-37	141.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WZS2_k127_465213_10	926569.ANT_10420	3.373e-135	442.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WZS2_k127_465213_23	926569.ANT_10430	6.884e-41	159.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WZS2_k127_465213_28	926569.ANT_10440	8.365e-30	121.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
WZS2_k127_465213_1	926569.ANT_10450	3.314e-275	865.0	COG1009@1|root,COG1009@2|Bacteria,2G5XJ@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
WZS2_k127_465213_13	926569.ANT_08410	2.365e-128	427.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WZS2_k127_465213_5	926569.ANT_10470	1.147e-176	567.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
WZS2_k127_465213_12	926569.ANT_10480	4.413e-132	436.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WZS2_k127_465213_22	926569.ANT_10520	1.406e-57	214.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WZS2_k127_465213_31	485913.Krac_8499	3.057e-13	72.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WZS2_k127_465213_20	926569.ANT_10540	2.683e-73	255.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
WZS2_k127_465213_3	926569.ANT_10550	2.944e-194	619.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS2_k127_465213_30	269799.Gmet_0191	3.8e-15	84.0	COG2199@1|root,COG3706@2|Bacteria,1NFQH@1224|Proteobacteria,42S2B@68525|delta/epsilon subdivisions,2WX0B@28221|Deltaproteobacteria,43VG9@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WZS2_k127_465213_29	452652.KSE_25980	6.187e-23	108.0	COG0501@1|root,COG0501@2|Bacteria,2GKJQ@201174|Actinobacteria,2M0BB@2063|Kitasatospora	201174|Actinobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
WZS2_k127_465213_9	316274.Haur_4945	3.49e-142	471.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	2|Bacteria	S	PFAM ABC transporter related	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS2_k127_465213_26	604331.AUHY01000005_gene808	1.035e-36	143.0	COG0589@1|root,COG0589@2|Bacteria,1WJW6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
WZS2_k127_465213_0	926569.ANT_10570	0.0	1010.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WZS2_k127_465213_27	926569.ANT_10580	9.855e-31	125.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WZS2_k127_465213_6	1279009.ADICEAN_03140	1.407e-165	539.0	COG0366@1|root,COG0366@2|Bacteria,4NEXF@976|Bacteroidetes,47MR6@768503|Cytophagia	976|Bacteroidetes	G	PFAM Alpha amylase, catalytic	-	GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070	3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,BACON
WZS2_k127_4712264_0	926569.ANT_03590	7.9e-191	631.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
WZS2_k127_4712264_2	326427.Cagg_2962	1.379e-43	184.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi,375BC@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_8
WZS2_k127_4712264_1	926569.ANT_00530	1.586e-138	453.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
WZS2_k127_4731615_2	1196323.ALKF01000198_gene2404	1.858e-113	383.0	COG1070@1|root,COG1070@2|Bacteria,1W6WP@1239|Firmicutes,4IH6F@91061|Bacilli,26W8K@186822|Paenibacillaceae	91061|Bacilli	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
WZS2_k127_4731615_3	1340434.AXVA01000003_gene1496	1.562e-99	333.0	COG0191@1|root,COG0191@2|Bacteria,1UYHC@1239|Firmicutes,4IN11@91061|Bacilli,1ZMH1@1386|Bacillus	91061|Bacilli	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
WZS2_k127_4731615_0	1131730.BAVI_16847	9.353e-307	960.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HF4F@91061|Bacilli,1ZQWV@1386|Bacillus	91061|Bacilli	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WZS2_k127_4731615_1	937777.Deipe_0063	2.509e-245	784.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WZS2_k127_4731615_4	1131730.BAVI_16842	9.468e-68	236.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,4HH1R@91061|Bacilli,1ZICD@1386|Bacillus	91061|Bacilli	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WZS2_k127_4854257_1	926569.ANT_13410	3.97e-106	359.0	COG0477@1|root,COG2814@2|Bacteria,2GBP2@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_4854257_3	926569.ANT_04430	2.246e-16	82.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi	200795|Chloroflexi	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
WZS2_k127_4854257_4	1484479.DI14_08570	4.617e-09	62.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,3WFN8@539002|Bacillales incertae sedis	91061|Bacilli	S	Cyclic-di-AMP receptor	yaaQ	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
WZS2_k127_4854257_0	357808.RoseRS_4025	1.057e-175	610.0	COG2319@1|root,COG2319@2|Bacteria,2G86V@200795|Chloroflexi,374S2@32061|Chloroflexia	32061|Chloroflexia	KLT	WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
WZS2_k127_4854257_2	926569.ANT_20460	6.609e-105	352.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi	200795|Chloroflexi	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
WZS2_k127_4860038_5	1304875.JAFZ01000002_gene325	1.991e-60	211.0	COG1132@1|root,COG1132@2|Bacteria,3TA8S@508458|Synergistetes	508458|Synergistetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WZS2_k127_4860038_7	383372.Rcas_2253	2.845e-47	189.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,2G6X8@200795|Chloroflexi,3758G@32061|Chloroflexia	32061|Chloroflexia	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc
WZS2_k127_4860038_0	234267.Acid_2679	1.278e-239	762.0	COG1472@1|root,COG1472@2|Bacteria,3Y3QE@57723|Acidobacteria	57723|Acidobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WZS2_k127_4860038_8	926550.CLDAP_11670	5.429e-35	139.0	COG3945@1|root,COG3945@2|Bacteria,2G96X@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WZS2_k127_4860038_3	572477.Alvin_0810	4.375e-109	362.0	COG1143@1|root,COG1143@2|Bacteria,1QVAQ@1224|Proteobacteria,1T4SQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
WZS2_k127_4860038_2	572477.Alvin_0809	8.588e-115	376.0	COG0543@1|root,COG0543@2|Bacteria,1MV72@1224|Proteobacteria,1T4D8@1236|Gammaproteobacteria,1X2TA@135613|Chromatiales	135613|Chromatiales	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
WZS2_k127_4860038_4	572477.Alvin_0808	1.13e-102	340.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria,1WYVW@135613|Chromatiales	135613|Chromatiales	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
WZS2_k127_4860038_1	572477.Alvin_0807	1.129e-181	577.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,1WY2T@135613|Chromatiales	135613|Chromatiales	C	PFAM Nickel-dependent hydrogenase, large subunit	-	-	-	-	-	-	-	-	-	-	-	-	NiFeSe_Hases
WZS2_k127_4860038_10	443144.GM21_0362	5.663e-20	95.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria,43VTP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
WZS2_k127_4860038_9	237368.SCABRO_02485	1.418e-30	125.0	COG0745@1|root,COG0745@2|Bacteria	237368.SCABRO_02485|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_4860038_6	237368.SCABRO_02484	1.137e-53	212.0	COG0642@1|root,COG2205@2|Bacteria	237368.SCABRO_02484|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_4860661_7	555779.Dthio_PD3223	9.664e-39	150.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WIT3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase, DHPS	-	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WZS2_k127_4860661_2	429009.Adeg_0338	2.269e-152	506.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WZS2_k127_4860661_3	555779.Dthio_PD3225	4.263e-114	382.0	COG1456@1|root,COG1456@2|Bacteria,1R4RE@1224|Proteobacteria,42M89@68525|delta/epsilon subdivisions,2WJVQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
WZS2_k127_4860661_4	903818.KI912268_gene1657	4.619e-90	306.0	COG2069@1|root,COG2069@2|Bacteria	2|Bacteria	C	one-carbon metabolic process	acsD	-	1.2.7.4,2.1.1.245	ko:K00194,ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R07157,R08034,R09096,R10219,R10243	RC00004,RC00113,RC00250,RC02800,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
WZS2_k127_4860661_9	272557.APE_2178.1	8.37e-06	55.0	COG0517@1|root,arCOG00600@2157|Archaea,2XQKZ@28889|Crenarchaeota	28889|Crenarchaeota	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WZS2_k127_4860661_0	555779.Dthio_PD3239	5.248e-266	839.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
WZS2_k127_4860661_1	909663.KI867150_gene97	1.633e-218	696.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
WZS2_k127_4860661_6	1125863.JAFN01000001_gene3473	1.628e-39	154.0	COG1247@1|root,COG1247@2|Bacteria,1PBZE@1224|Proteobacteria,42VVQ@68525|delta/epsilon subdivisions,2WR9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_4
WZS2_k127_4860661_8	316067.Geob_2432	4.558e-16	85.0	COG0664@1|root,COG0664@2|Bacteria,1PSVY@1224|Proteobacteria,42XY7@68525|delta/epsilon subdivisions,2WTBB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WZS2_k127_4860661_5	926569.ANT_18070	1.824e-57	203.0	COG0698@1|root,COG0698@2|Bacteria,2G6SM@200795|Chloroflexi	200795|Chloroflexi	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WZS2_k127_4890430_4	926569.ANT_02690	2.686e-54	193.0	COG1884@1|root,COG1884@2|Bacteria,2G5TP@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
WZS2_k127_4890430_5	525904.Tter_0302	2.555e-40	163.0	COG1432@1|root,COG1432@2|Bacteria,2NR68@2323|unclassified Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
WZS2_k127_4890430_0	485913.Krac_11199	0.0	1349.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WZS2_k127_4890430_2	926569.ANT_11950	8.934e-263	823.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
WZS2_k127_4890430_1	1128421.JAGA01000002_gene1344	0.0	1110.0	COG1404@1|root,COG1404@2|Bacteria,2NQYY@2323|unclassified Bacteria	2|Bacteria	O	PA domain	vpr	GO:0005575,GO:0005576	-	ko:K14647	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	FlgD_ig,Inhibitor_I9,PA,Peptidase_S8,SLH,fn3_5
WZS2_k127_4890430_6	180332.JTGN01000009_gene4265	6.553e-06	55.0	COG2306@1|root,COG2306@2|Bacteria,1VD0J@1239|Firmicutes,24MAM@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
WZS2_k127_4890430_3	1541960.KQ78_01705	7.27e-72	259.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1400,PAF-AH_p_II
WZS2_k127_4908769_2	926569.ANT_08920	4.267e-93	312.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS2_k127_4908769_3	926569.ANT_10890	8.345e-85	287.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM metal dependent phophohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS2_k127_4908769_4	926569.ANT_10900	4.113e-73	252.0	COG2949@1|root,COG2949@2|Bacteria,2G6VI@200795|Chloroflexi	200795|Chloroflexi	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
WZS2_k127_4908769_5	1131269.AQVV01000005_gene388	2.828e-71	255.0	COG3639@1|root,COG3639@2|Bacteria	2|Bacteria	P	organic phosphonate transmembrane transporter activity	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
WZS2_k127_4908769_6	1307761.L21SP2_1484	7.897e-70	254.0	COG3639@1|root,COG3639@2|Bacteria,2J6TW@203691|Spirochaetes	203691|Spirochaetes	U	ABC transporter (Permease)	-	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
WZS2_k127_4908769_1	1307761.L21SP2_1483	1.186e-97	327.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
WZS2_k127_4908769_7	926569.ANT_10910	1.664e-48	187.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
WZS2_k127_4908769_0	926569.ANT_15320	2.234e-127	418.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cytoplasmic peptidoglycan synthetase domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS2_k127_4919200_6	391625.PPSIR1_36492	2.938e-11	72.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,P_proprotein
WZS2_k127_4919200_0	926569.ANT_04370	0.0	1060.0	COG0187@1|root,COG0187@2|Bacteria,2G67C@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WZS2_k127_4919200_2	880073.Calab_0989	8.737e-154	491.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
WZS2_k127_4919200_5	1173028.ANKO01000018_gene1192	9.756e-25	115.0	COG2518@1|root,COG2518@2|Bacteria,1GR78@1117|Cyanobacteria,1HE58@1150|Oscillatoriales	1117|Cyanobacteria	O	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Methyltransf_21
WZS2_k127_4919200_1	926569.ANT_22580	3.385e-169	555.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
WZS2_k127_4919200_4	926569.ANT_02380	7.655e-26	110.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WZS2_k127_492281_0	383372.Rcas_3439	2.317e-274	867.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,374Z8@32061|Chloroflexia	32061|Chloroflexia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS2_k127_492281_1	926550.CLDAP_04430	2.219e-122	408.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi	200795|Chloroflexi	K	PFAM AAA-4 family protein	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_DeoR
WZS2_k127_492281_2	1382356.JQMP01000003_gene1940	0.0002947	52.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,2G99E@200795|Chloroflexi,27XPH@189775|Thermomicrobia	189775|Thermomicrobia	MT	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
WZS2_k127_5030588_6	1123274.KB899410_gene3488	4.148e-25	112.0	COG0204@1|root,COG0204@2|Bacteria,2JAHQ@203691|Spirochaetes	203691|Spirochaetes	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WZS2_k127_5030588_1	1123274.KB899410_gene3489	1.309e-79	276.0	COG1597@1|root,COG1597@2|Bacteria,2J9G6@203691|Spirochaetes	203691|Spirochaetes	I	PFAM Diacylglycerol kinase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WZS2_k127_5030588_2	765914.ThisiDRAFT_2217	9.283e-79	287.0	COG0715@1|root,COG2199@1|root,COG0715@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RZ2Z@1236|Gammaproteobacteria,1X2BY@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS
WZS2_k127_5030588_4	926569.ANT_14640	3.168e-41	160.0	COG2802@1|root,COG2802@2|Bacteria,2G76N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase S16 lon domain protein	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
WZS2_k127_5030588_0	926569.ANT_16070	4.277e-128	420.0	COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Peptidase_M24
WZS2_k127_5030588_3	926569.ANT_23660	4.753e-75	263.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
WZS2_k127_5030588_5	926569.ANT_14030	1.585e-25	107.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WZS2_k127_5153930_1	1128421.JAGA01000001_gene2345	7.13e-122	407.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CARDB,CBM_3,DUF4091,HYR,Kelch_1,MAM,PA14,PKD,Peptidase_M43,Reprolysin_3
WZS2_k127_5153930_3	765420.OSCT_1870	8.02e-78	271.0	COG4149@1|root,COG4149@2|Bacteria,2G6FA@200795|Chloroflexi,376FE@32061|Chloroflexia	32061|Chloroflexia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
WZS2_k127_5153930_2	1128421.JAGA01000002_gene1244	1.179e-79	274.0	COG0725@1|root,COG0725@2|Bacteria,2NQT8@2323|unclassified Bacteria	2|Bacteria	P	Bacterial extracellular solute-binding protein	modA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
WZS2_k127_5153930_0	272563.CD630_05820	3.027e-189	617.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25UNR@186804|Peptostreptococcaceae	186801|Clostridia	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WZS2_k127_5178956_8	485913.Krac_6667	1.11e-06	51.0	COG1290@1|root,COG1290@2|Bacteria,2G8QQ@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
WZS2_k127_5178956_1	671143.DAMO_0766	1.065e-183	597.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	pcmB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9	ko:K03388,ko:K12527	ko00450,ko00680,ko01100,ko01120,ko01200,map00450,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R07229,R11928,R11931,R11943,R11944	RC00011,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,FlpD,Pyr_redox_2,Pyr_redox_3
WZS2_k127_5178956_7	1212548.B381_09226	4.619e-16	82.0	COG2010@1|root,COG3474@1|root,COG2010@2|Bacteria,COG3474@2|Bacteria,1RDSI@1224|Proteobacteria,1S4BC@1236|Gammaproteobacteria,1Z0UZ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
WZS2_k127_5178956_2	1123360.thalar_02888	2.558e-63	244.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2UQID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,FlpD
WZS2_k127_5178956_0	926550.CLDAP_28410	2.553e-201	640.0	COG0843@1|root,COG0843@2|Bacteria,2G628@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit I	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
WZS2_k127_5178956_5	926550.CLDAP_28420	7.747e-47	175.0	COG1622@1|root,COG1622@2|Bacteria,2G8QU@200795|Chloroflexi	200795|Chloroflexi	C	cytochrome c oxidase subunit II	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
WZS2_k127_5178956_6	288000.BBta_4537	2.916e-25	112.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria,3JX1P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
WZS2_k127_5178956_4	479434.Sthe_0241	3.569e-50	185.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,27Z5W@189775|Thermomicrobia	189775|Thermomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
WZS2_k127_5178956_3	479434.Sthe_0242	3.811e-53	195.0	COG1999@1|root,COG1999@2|Bacteria,2G9UW@200795|Chloroflexi,27ZCD@189775|Thermomicrobia	189775|Thermomicrobia	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	-
WZS2_k127_5241751_9	926569.ANT_15180	3.488e-08	55.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
WZS2_k127_5241751_6	926569.ANT_15190	1.08e-20	98.0	2DTJR@1|root,33KPB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_5241751_1	926569.ANT_15200	4.662e-126	413.0	COG0387@1|root,COG0387@2|Bacteria,2G6GE@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
WZS2_k127_5241751_4	1173020.Cha6605_5319	4.245e-39	162.0	COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Diacylglycerol kinase, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WZS2_k127_5241751_2	926569.ANT_15210	3.336e-96	325.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WZS2_k127_5241751_3	926569.ANT_15220	2.253e-70	245.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WZS2_k127_5241751_7	926569.ANT_15230	1.618e-19	90.0	COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi	200795|Chloroflexi	J	ribosomal protein L28	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WZS2_k127_5241751_5	926569.ANT_15240	1.504e-34	135.0	COG1302@1|root,COG1302@2|Bacteria,2G76I@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WZS2_k127_5241751_0	926569.ANT_15250	1.108e-216	686.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
WZS2_k127_5241751_8	1196323.ALKF01000205_gene4095	8.83e-17	85.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,26S8K@186822|Paenibacillaceae	91061|Bacilli	S	DegV family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_5317545_6	926569.ANT_03840	7.426e-60	210.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WZS2_k127_5317545_4	926569.ANT_08620	4.098e-86	292.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi	200795|Chloroflexi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WZS2_k127_5317545_8	926569.ANT_28270	8.91e-21	94.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WZS2_k127_5317545_7	926569.ANT_28280	1.909e-33	130.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WZS2_k127_5317545_1	357808.RoseRS_1785	3.574e-137	444.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi,3766V@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WZS2_k127_5317545_0	926569.ANT_28320	0.0	1830.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
WZS2_k127_5317545_3	472759.Nhal_3067	4.22e-88	303.0	COG0707@1|root,COG0707@2|Bacteria,1QW3F@1224|Proteobacteria,1T2RC@1236|Gammaproteobacteria,1X2NR@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_5317545_5	926569.ANT_03490	1.518e-83	285.0	COG4589@1|root,COG4589@2|Bacteria,2G6QV@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WZS2_k127_5317545_2	926569.ANT_03500	6.46e-104	342.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WZS2_k127_5337085_7	926554.KI912636_gene3086	5.462e-12	74.0	COG0477@1|root,COG2814@2|Bacteria,1WJCM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS2_k127_5337085_0	926569.ANT_08730	0.0	1308.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
WZS2_k127_5337085_6	913865.DOT_1268	6.149e-24	109.0	2DN1Q@1|root,32V01@2|Bacteria,1UM49@1239|Firmicutes,25GAG@186801|Clostridia,267EI@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
WZS2_k127_5337085_3	525904.Tter_0098	1.061e-105	357.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
WZS2_k127_5337085_2	926569.ANT_07770	4.622e-131	423.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WZS2_k127_5337085_5	1260251.SPISAL_03750	3.401e-32	135.0	COG1814@1|root,COG1814@2|Bacteria,1RBDP@1224|Proteobacteria,1T04K@1236|Gammaproteobacteria,1X0M0@135613|Chromatiales	135613|Chromatiales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
WZS2_k127_5337085_1	926569.ANT_18060	1.278e-141	458.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
WZS2_k127_5337085_4	926569.ANT_18080	1.785e-40	152.0	COG0021@1|root,COG0021@2|Bacteria,2G63Z@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WZS2_k127_5385534_0	926569.ANT_11410	8.238e-221	703.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
WZS2_k127_5385534_2	404380.Gbem_1706	1.405e-77	263.0	COG2406@1|root,COG2406@2|Bacteria,1RE25@1224|Proteobacteria,42PJ1@68525|delta/epsilon subdivisions,2WNTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ferritin Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
WZS2_k127_5385534_1	1499967.BAYZ01000089_gene5049	3.302e-89	300.0	COG1080@1|root,COG1080@2|Bacteria,2NNQF@2323|unclassified Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
WZS2_k127_5388279_8	561175.KB894093_gene4029	8.612e-17	89.0	COG2267@1|root,COG2267@2|Bacteria,2GJ78@201174|Actinobacteria,4ER3I@85012|Streptosporangiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS2_k127_5388279_6	926550.CLDAP_24330	4.357e-89	302.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	2.1.1.6	ko:K00545	ko00140,ko00350,ko00965,ko01100,ko04728,map00140,map00350,map00965,map01100,map04728	-	R02534,R02920,R03304,R04301,R04762,R04764,R04881,R04887	RC00003,RC00392	ko00000,ko00001,ko01000,ko04147	-	-	-	Methyltransf_3
WZS2_k127_5388279_2	357808.RoseRS_4108	5.808e-164	521.0	COG4177@1|root,COG4177@2|Bacteria,2G8ZK@200795|Chloroflexi,375J2@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS2_k127_5388279_1	357808.RoseRS_4107	5.308e-207	655.0	COG0559@1|root,COG0559@2|Bacteria,2GBUW@200795|Chloroflexi,376UV@32061|Chloroflexia	32061|Chloroflexia	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS2_k127_5388279_4	357808.RoseRS_4106	1.038e-113	370.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374V9@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WZS2_k127_5388279_3	357808.RoseRS_4105	3.947e-130	418.0	COG0411@1|root,COG0411@2|Bacteria,2GABI@200795|Chloroflexi,376AR@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS2_k127_5388279_0	357808.RoseRS_4104	4.336e-228	715.0	COG0683@1|root,COG0683@2|Bacteria,2G904@200795|Chloroflexi,3754R@32061|Chloroflexia	32061|Chloroflexia	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WZS2_k127_5388279_7	1192034.CAP_8417	2.069e-85	291.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria	1224|Proteobacteria	I	Alpha beta hydrolase	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
WZS2_k127_5388279_5	1120973.AQXL01000102_gene2649	2.568e-113	378.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,278QU@186823|Alicyclobacillaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WZS2_k127_5447422_5	1128421.JAGA01000003_gene3534	1.761e-57	207.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WZS2_k127_5447422_4	926569.ANT_04570	1.23e-72	250.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
WZS2_k127_5447422_2	926569.ANT_27550	4.148e-93	311.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi	200795|Chloroflexi	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
WZS2_k127_5447422_1	926569.ANT_27540	1.694e-125	413.0	COG0460@1|root,COG0460@2|Bacteria,2G6PU@200795|Chloroflexi	200795|Chloroflexi	E	homoserine dehydrogenase	metM	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
WZS2_k127_5447422_3	1519464.HY22_07420	3.404e-82	284.0	COG3380@1|root,COG3380@2|Bacteria	2|Bacteria	S	monoamine oxidase activity	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
WZS2_k127_5447422_6	1128421.JAGA01000002_gene1190	2.183e-57	203.0	COG3059@1|root,COG3059@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
WZS2_k127_5447422_0	316274.Haur_4751	5.355e-202	645.0	COG1164@1|root,COG1164@2|Bacteria,2G5UV@200795|Chloroflexi,376XT@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WZS2_k127_5455517_5	264732.Moth_1339	9.98e-71	249.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,42EQ2@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
WZS2_k127_5455517_1	926569.ANT_05930	1.342e-143	463.0	COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
WZS2_k127_5455517_4	926569.ANT_05940	1.984e-84	285.0	COG0512@1|root,COG0512@2|Bacteria,2G69G@200795|Chloroflexi	200795|Chloroflexi	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
WZS2_k127_5455517_0	926569.ANT_05950	2.235e-173	557.0	COG0147@1|root,COG1169@1|root,COG0147@2|Bacteria,COG1169@2|Bacteria,2G5M7@200795|Chloroflexi	200795|Chloroflexi	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
WZS2_k127_5455517_8	926569.ANT_23670	2.326e-07	55.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
WZS2_k127_5455517_2	1089548.KI783301_gene1376	3.514e-101	338.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,4H9S8@91061|Bacilli,3WF8Q@539002|Bacillales incertae sedis	91061|Bacilli	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
WZS2_k127_5455517_6	765420.OSCT_0762	4.823e-48	183.0	COG1893@1|root,COG1893@2|Bacteria,2G9PB@200795|Chloroflexi,3772C@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
WZS2_k127_5455517_3	1128421.JAGA01000002_gene351	1.868e-93	315.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
WZS2_k127_5455517_7	926569.ANT_11940	7.544e-33	129.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WZS2_k127_5527708_5	1242864.D187_003310	1.97e-85	289.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WZS2_k127_5527708_4	404589.Anae109_1754	2.195e-166	529.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WZS2_k127_5527708_0	404589.Anae109_1753	9.961e-251	783.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
WZS2_k127_5527708_6	926569.ANT_03320	1.051e-81	276.0	COG0066@1|root,COG0066@2|Bacteria,2G6JE@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
WZS2_k127_5527708_2	1267535.KB906767_gene3365	2.115e-227	711.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria,2JI0J@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
WZS2_k127_5527708_1	1254432.SCE1572_22465	1.076e-234	737.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WIUZ@28221|Deltaproteobacteria,2YUCI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
WZS2_k127_5527708_3	439235.Dalk_0563	1.058e-175	556.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,42MRS@68525|delta/epsilon subdivisions,2WJW8@28221|Deltaproteobacteria,2MIRN@213118|Desulfobacterales	28221|Deltaproteobacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
WZS2_k127_5527708_7	926569.ANT_03270	2.802e-60	214.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi	200795|Chloroflexi	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
WZS2_k127_5527708_8	926569.ANT_03260	4.722e-33	128.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi	200795|Chloroflexi	H	Thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WZS2_k127_555578_2	383372.Rcas_0455	6.214e-42	159.0	COG3503@1|root,COG3503@2|Bacteria,2G83W@200795|Chloroflexi,37673@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
WZS2_k127_555578_1	926550.CLDAP_31330	3.522e-101	338.0	COG0110@1|root,COG0110@2|Bacteria,2G7YT@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WZS2_k127_555578_0	926550.CLDAP_27870	8.617e-246	777.0	COG1520@1|root,COG4085@1|root,COG1520@2|Bacteria,COG4085@2|Bacteria,2G86P@200795|Chloroflexi	200795|Chloroflexi	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
WZS2_k127_5619335_7	370438.PTH_2753	6.604e-67	258.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,260C9@186807|Peptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
WZS2_k127_5619335_1	926569.ANT_05570	1.946e-128	419.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
WZS2_k127_5619335_3	926569.ANT_12620	1.743e-96	322.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi	200795|Chloroflexi	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WZS2_k127_5619335_9	926569.ANT_12640	9.3e-57	205.0	COG1670@1|root,COG1670@2|Bacteria,2G73Y@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS2_k127_5619335_2	926569.ANT_12660	6.77e-97	332.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
WZS2_k127_5619335_8	926569.ANT_12670	8.474e-61	212.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WZS2_k127_5619335_12	485913.Krac_9379	6.011e-47	174.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS2_k127_5619335_0	926569.ANT_05200	2.899e-213	676.0	COG0664@1|root,COG0664@2|Bacteria,2G63K@200795|Chloroflexi	200795|Chloroflexi	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_5619335_10	926569.ANT_11330	6.038e-52	187.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WZS2_k127_5619335_4	926569.ANT_20400	1.455e-89	312.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,2GBIC@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS2_k127_5619335_5	926569.ANT_20410	3.068e-88	296.0	COG0745@1|root,COG0745@2|Bacteria,2G6JT@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_5619335_11	926550.CLDAP_28020	1.136e-51	186.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	badR	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
WZS2_k127_5619335_6	926569.ANT_05080	7.237e-72	246.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
WZS2_k127_5621469_0	2002.JOEQ01000016_gene7347	8.01e-214	710.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales	201174|Actinobacteria	M	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,WD40
WZS2_k127_5621469_1	357808.RoseRS_3616	1.173e-192	619.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
WZS2_k127_5621469_2	1536772.R70723_24115	8.39e-168	540.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,4HEKC@91061|Bacilli,26TSJ@186822|Paenibacillaceae	91061|Bacilli	G	Alpha amylase, catalytic domain	-	-	2.4.1.329	ko:K21350	-	-	-	-	ko00000,ko01000	-	GH13	-	Alpha-amylase
WZS2_k127_5621469_8	1033743.CAES01000002_gene1861	8.773e-71	255.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,4HDE3@91061|Bacilli,26RTN@186822|Paenibacillaceae	91061|Bacilli	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
WZS2_k127_5621469_6	211114.JOEF01000025_gene190	1.861e-106	352.0	COG0395@1|root,COG0395@2|Bacteria,2GJNJ@201174|Actinobacteria,4E0YP@85010|Pseudonocardiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WZS2_k127_5621469_5	1150864.MILUP08_45150	4.29e-111	366.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4DBFS@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WZS2_k127_5621469_4	1150864.MILUP08_45151	1.665e-127	425.0	COG1653@1|root,COG1653@2|Bacteria,2GJYT@201174|Actinobacteria,4DA6R@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WZS2_k127_5621469_3	1121382.JQKG01000003_gene4233	6.81e-144	475.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM26
WZS2_k127_5621469_9	316274.Haur_2392	6.976e-41	173.0	COG1874@1|root,COG1874@2|Bacteria,2G8DQ@200795|Chloroflexi,377PY@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 35 family	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
WZS2_k127_5621469_7	211114.JOEF01000025_gene185	1.013e-82	284.0	COG0491@1|root,COG0491@2|Bacteria,2IBAX@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS2_k127_5630754_0	926569.ANT_08450	8.364e-176	558.0	COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
WZS2_k127_5630754_8	926569.ANT_08500	5.69e-61	224.0	COG0508@1|root,COG1043@1|root,COG1086@1|root,COG0508@2|Bacteria,COG1043@2|Bacteria,COG1086@2|Bacteria,2G9FU@200795|Chloroflexi	200795|Chloroflexi	GM	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WZS2_k127_5630754_3	1121406.JAEX01000016_gene1869	2.605e-86	297.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42MBM@68525|delta/epsilon subdivisions,2WJKG@28221|Deltaproteobacteria,2M9IA@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Transketolase, pyrimidine binding domain	pdhB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2753	Transket_pyr,Transketolase_C
WZS2_k127_5630754_4	536019.Mesop_2093	9.936e-80	277.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2UQUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
WZS2_k127_5630754_7	1121920.AUAU01000025_gene2333	1.636e-61	222.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
WZS2_k127_5630754_5	926569.ANT_01070	3.041e-76	261.0	COG2148@1|root,COG2148@2|Bacteria,2G7P3@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
WZS2_k127_5630754_6	926569.ANT_18940	2.084e-67	237.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi	200795|Chloroflexi	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
WZS2_k127_5630754_2	926569.ANT_02410	3.89e-89	304.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pelF	-	-	ko:K21011,ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4,Glycos_transf_1
WZS2_k127_5630754_1	926569.ANT_23150	1.006e-108	365.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WZS2_k127_5785558_16	323261.Noc_0114	5.447e-34	151.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1WX09@135613|Chromatiales	135613|Chromatiales	P	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
WZS2_k127_5785558_11	1125863.JAFN01000001_gene1889	1.244e-72	273.0	COG0457@1|root,COG0457@2|Bacteria,1QXGV@1224|Proteobacteria,42RIF@68525|delta/epsilon subdivisions,2WNC6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
WZS2_k127_5785558_7	926550.CLDAP_04740	1.031e-90	308.0	COG3833@1|root,COG3833@2|Bacteria,2G8IJ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WZS2_k127_5785558_3	309799.DICTH_0549	1.83e-103	355.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	malF	GO:0003674,GO:0003824,GO:0005215,GO:0005363,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009987,GO:0015144,GO:0015154,GO:0015157,GO:0015399,GO:0015405,GO:0015422,GO:0015423,GO:0015766,GO:0015768,GO:0015772,GO:0015774,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033037,GO:0033554,GO:0034219,GO:0042623,GO:0042626,GO:0042956,GO:0043190,GO:0043211,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990060,GO:1990351	-	ko:K02025,ko:K10109,ko:K10118,ko:K15771	ko02010,map02010	M00194,M00196,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.22,3.A.1.1.28	-	iZ_1308.Z5631	BPD_transp_1,MalF_P2,TM_PBP2_N
WZS2_k127_5785558_20	926564.KI911714_gene2687	3.983e-20	105.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4F3GE@85017|Promicromonosporaceae	201174|Actinobacteria	M	Alpha-amylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372
WZS2_k127_5785558_5	926550.CLDAP_04710	6.923e-95	330.0	COG2182@1|root,COG2182@2|Bacteria,2G91A@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
WZS2_k127_5785558_1	926569.ANT_11020	1.202e-139	456.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2G6IH@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
WZS2_k127_5785558_13	1500301.JQMF01000013_gene4541	6.617e-56	207.0	COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria,2TUAG@28211|Alphaproteobacteria,4BBDG@82115|Rhizobiaceae	28211|Alphaproteobacteria	EM	Belongs to the DapA family	dapAb	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WZS2_k127_5785558_8	926569.ANT_10920	4.779e-88	301.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WZS2_k127_5785558_15	525904.Tter_0583	6.802e-36	145.0	2AZDP@1|root,31RMA@2|Bacteria,2NRKB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
WZS2_k127_5785558_19	926569.ANT_22500	7.696e-25	106.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
WZS2_k127_5785558_14	926569.ANT_13860	2.672e-50	188.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
WZS2_k127_5785558_6	926569.ANT_13890	6.755e-92	307.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_5785558_4	926569.ANT_13900	6.325e-100	340.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_13900|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_5785558_2	926569.ANT_14180	1.853e-126	421.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WZS2_k127_5785558_10	926569.ANT_14170	1.047e-75	259.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WZS2_k127_5785558_9	926569.ANT_14160	1.346e-86	289.0	COG1435@1|root,COG1435@2|Bacteria,2G6DP@200795|Chloroflexi	200795|Chloroflexi	F	PFAM thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WZS2_k127_5785558_12	926569.ANT_25140	1.315e-65	227.0	COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi	200795|Chloroflexi	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WZS2_k127_5785558_17	926569.ANT_25130	1.682e-31	125.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WZS2_k127_5785558_18	479434.Sthe_1805	1.575e-28	117.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi,27YJB@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WZS2_k127_5785558_0	926569.ANT_10870	2.165e-282	899.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WZS2_k127_5785558_22	926569.ANT_12120	3.383e-05	49.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1
WZS2_k127_5789033_2	926569.ANT_29320	5.045e-52	187.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WZS2_k127_5789033_3	608506.COB47_0049	4.406e-51	191.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,42J3Y@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
WZS2_k127_5789033_1	445972.ANACOL_02160	1.625e-80	276.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3WHVP@541000|Ruminococcaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	rfbB	-	-	ko:K01990,ko:K09691	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC_tran
WZS2_k127_5789033_4	869210.Marky_0733	1.184e-26	128.0	COG1216@1|root,COG1216@2|Bacteria,1WKQS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
WZS2_k127_5789033_0	221288.JH992901_gene5375	1.245e-166	557.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gumK	-	2.4.1.264	ko:K13659	-	-	R09732	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT70	-	Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2
WZS2_k127_581689_2	316274.Haur_3072	1.44e-153	498.0	COG2124@1|root,COG2124@2|Bacteria,2G83S@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
WZS2_k127_581689_3	880072.Desac_2390	7.485e-96	330.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MUDN@1224|Proteobacteria,42N3H@68525|delta/epsilon subdivisions,2WJSC@28221|Deltaproteobacteria,2MRMH@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
WZS2_k127_581689_5	1321778.HMPREF1982_01454	1.827e-45	173.0	COG0494@1|root,COG0494@2|Bacteria,1VM6Y@1239|Firmicutes	1239|Firmicutes	L	DNA mismatch repair protein MutT	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS2_k127_581689_4	926569.ANT_16090	9.008e-59	210.0	COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi	200795|Chloroflexi	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS2_k127_581689_0	1174528.JH992892_gene6439	4.582e-201	634.0	COG3033@1|root,COG3033@2|Bacteria,1G33V@1117|Cyanobacteria	1117|Cyanobacteria	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
WZS2_k127_581689_1	794846.AJQU01000075_gene3473	3.866e-176	565.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,2TSN9@28211|Alphaproteobacteria,4B8YD@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
WZS2_k127_5849801_2	1210908.HSB1_13560	2.789e-73	258.0	COG1041@1|root,arCOG00047@2157|Archaea	2157|Archaea	L	RNA methylase	trmG10	GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363	2.1.1.213	ko:K07446	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	THUMP,UPF0020
WZS2_k127_5849801_0	316274.Haur_4586	5.294e-123	404.0	COG0667@1|root,COG0667@2|Bacteria,2G7TU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS2_k127_5849801_1	1128421.JAGA01000001_gene2345	5.97e-121	409.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CARDB,CBM_3,DUF4091,HYR,Kelch_1,MAM,PA14,PKD,Peptidase_M43,Reprolysin_3
WZS2_k127_5853701_2	926569.ANT_11970	5.228e-117	386.0	COG1148@1|root,COG1148@2|Bacteria,2G7GY@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_5853701_0	522306.CAP2UW1_3003	5.263e-237	756.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,2VJYR@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF5110,Glyco_hydro_31
WZS2_k127_5853701_7	749222.Nitsa_1712	4.521e-81	283.0	COG1216@1|root,COG1216@2|Bacteria,1N78N@1224|Proteobacteria	1224|Proteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_5853701_4	671143.DAMO_3032	3.515e-102	338.0	COG0861@1|root,COG0861@2|Bacteria,2NQFQ@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	-	-	-	-	-	-	-	-	-	TerC
WZS2_k127_5853701_9	357808.RoseRS_0012	6.079e-64	229.0	COG0204@1|root,COG0204@2|Bacteria,2G92W@200795|Chloroflexi,3779N@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WZS2_k127_5853701_10	1283300.ATXB01000002_gene3083	4.065e-26	120.0	COG2230@1|root,COG2230@2|Bacteria,1QUR4@1224|Proteobacteria,1RP3C@1236|Gammaproteobacteria,1XF6I@135618|Methylococcales	135618|Methylococcales	M	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS2_k127_5853701_6	926550.CLDAP_20700	5.545e-94	315.0	COG1136@1|root,COG1136@2|Bacteria,2G6K8@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_5853701_3	926550.CLDAP_20690	1.144e-111	373.0	COG0577@1|root,COG0577@2|Bacteria,2G6RX@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
WZS2_k127_5853701_13	765420.OSCT_2140	4.838e-18	97.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8X1@200795|Chloroflexi,376YI@32061|Chloroflexia	32061|Chloroflexia	MV	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
WZS2_k127_5853701_11	1303518.CCALI_00071	4.136e-25	113.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WZS2_k127_5853701_8	383372.Rcas_3770	1.388e-79	283.0	COG1819@1|root,COG1819@2|Bacteria,2G865@200795|Chloroflexi,375NW@32061|Chloroflexia	32061|Chloroflexia	CG	PFAM glycosyl transferase, family 28	-	-	2.4.1.173	ko:K05841	-	-	-	-	ko00000,ko01000,ko01003	-	GT1	-	Glyco_transf_28,UDPGT
WZS2_k127_5853701_5	383372.Rcas_4096	1.325e-100	343.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi,375GE@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_5853701_1	269797.Mbar_A1244	2.015e-170	548.0	COG0520@1|root,arCOG00065@2157|Archaea	2157|Archaea	E	COG0520 Selenocysteine lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WZS2_k127_5853701_14	309801.trd_1275	1.108e-06	58.0	29X1F@1|root,30IPT@2|Bacteria,2GA4G@200795|Chloroflexi,27Z7Q@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_5853701_12	926569.ANT_26560	1.008e-18	87.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi	200795|Chloroflexi	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_5853822_5	926550.CLDAP_26560	1.388e-59	220.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
WZS2_k127_5853822_7	926550.CLDAP_26570	2.684e-43	173.0	COG0845@1|root,COG0845@2|Bacteria,2G8Q8@200795|Chloroflexi	200795|Chloroflexi	M	secretion protein HlyD family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
WZS2_k127_5853822_9	926569.ANT_09420	2.339e-28	123.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.16.1.3,1.5.1.41	ko:K02823,ko:K05368	ko00240,ko00740,ko00860,ko01100,map00240,map00740,map00860,map01100	-	R00097,R05705	RC00126,RC00220	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WZS2_k127_5853822_10	383372.Rcas_4448	1.378e-26	119.0	COG0167@1|root,COG0167@2|Bacteria,2G6RH@200795|Chloroflexi,3760P@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WZS2_k127_5853822_0	706587.Desti_2950	3.042e-285	911.0	COG0067@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0070@2|Bacteria,1NZ4D@1224|Proteobacteria,43B3T@68525|delta/epsilon subdivisions,2X6HR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GXGXG motif	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GXGXG
WZS2_k127_5853822_1	880072.Desac_1036	1e-152	514.0	COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
WZS2_k127_5853822_2	1265505.ATUG01000002_gene1767	9.146e-76	284.0	COG2070@1|root,COG2070@2|Bacteria,1RH4W@1224|Proteobacteria,42T0D@68525|delta/epsilon subdivisions,2WPHF@28221|Deltaproteobacteria,2MN8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
WZS2_k127_5853822_4	357808.RoseRS_0017	9.482e-65	229.0	COG1309@1|root,COG1309@2|Bacteria,2GAFT@200795|Chloroflexi,375ZP@32061|Chloroflexia	32061|Chloroflexia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS2_k127_5853822_12	316274.Haur_3201	6.886e-14	79.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
WZS2_k127_5853822_11	1385519.N801_10215	2.125e-26	114.0	2DRYE@1|root,33DPC@2|Bacteria,2IS24@201174|Actinobacteria,4FHPE@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_5853822_8	1173026.Glo7428_1028	1.872e-42	162.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WZS2_k127_5853822_6	926560.KE387023_gene3760	2.784e-50	184.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,Malectin
WZS2_k127_5853822_3	1499967.BAYZ01000028_gene1280	5.661e-69	242.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WZS2_k127_5876175_4	926569.ANT_13200	1.027e-69	240.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
WZS2_k127_5876175_3	926569.ANT_13820	3.877e-76	262.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WZS2_k127_5876175_1	529884.Rhola_00001990	1.069e-153	499.0	COG0017@1|root,COG0017@2|Bacteria,2I2KQ@201174|Actinobacteria,4FKWR@85023|Microbacteriaceae	201174|Actinobacteria	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
WZS2_k127_5876175_2	926550.CLDAP_05030	1.485e-103	346.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WZS2_k127_5876175_5	926569.ANT_13800	1.014e-45	169.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
WZS2_k127_5876175_0	926569.ANT_13790	1.615e-251	781.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WZS2_k127_5876175_6	926569.ANT_13780	1.1e-27	115.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WZS2_k127_5888745_7	926569.ANT_19400	2.625e-59	208.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
WZS2_k127_5888745_5	926569.ANT_19390	1.638e-85	289.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
WZS2_k127_5888745_2	926569.ANT_30970	2.14e-103	338.0	COG1838@1|root,COG1838@2|Bacteria,2G74D@200795|Chloroflexi	200795|Chloroflexi	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01676,ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
WZS2_k127_5888745_0	926569.ANT_30960	8.14e-135	435.0	COG1951@1|root,COG1951@2|Bacteria,2G6YI@200795|Chloroflexi	200795|Chloroflexi	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01676,ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
WZS2_k127_5888745_6	1173027.Mic7113_1316	3.242e-73	262.0	COG0477@1|root,COG2814@2|Bacteria,1G2WB@1117|Cyanobacteria,1H7X9@1150|Oscillatoriales	1117|Cyanobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
WZS2_k127_5888745_10	1206101.AZXC01000010_gene148	9.874e-15	79.0	2E8H6@1|root,332VD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WZS2_k127_5888745_1	316274.Haur_1430	8.406e-115	392.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
WZS2_k127_5888745_9	264198.Reut_B4834	1.203e-15	92.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
WZS2_k127_5888745_8	1128421.JAGA01000001_gene2038	6.184e-52	210.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2NQ3V@2323|unclassified Bacteria	2|Bacteria	KT	COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,SpoIIE
WZS2_k127_5888745_4	459349.CLOAM1351	9.251e-87	297.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	ko:K14696	-	-	-	-	ko00000,ko02000	2.A.4.6	-	-	Cation_efflux,ZT_dimer
WZS2_k127_5888745_3	479434.Sthe_2033	3.156e-96	329.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_5888745_11	1123023.JIAI01000004_gene8077	6.157e-08	55.0	COG0154@1|root,COG0154@2|Bacteria,2GN7F@201174|Actinobacteria,4DZAM@85010|Pseudonocardiales	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS2_k127_5990275_4	400668.Mmwyl1_3485	7.994e-09	61.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1XJK7@135619|Oceanospirillales	135619|Oceanospirillales	P	Sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WZS2_k127_5990275_1	518766.Rmar_0188	8.423e-54	196.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes	976|Bacteroidetes	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WZS2_k127_5990275_5	526227.Mesil_1688	0.0007951	50.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
WZS2_k127_5990275_2	1521187.JPIM01000068_gene745	1.736e-44	173.0	COG1668@1|root,COG1668@2|Bacteria,2G76A@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
WZS2_k127_5990275_0	351160.LRC208	1.896e-107	358.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N95K@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_5990275_3	1254432.SCE1572_36870	2.219e-42	167.0	COG4377@1|root,COG4377@2|Bacteria,1QACG@1224|Proteobacteria,43DZN@68525|delta/epsilon subdivisions,2WZAB@28221|Deltaproteobacteria,2Z1PM@29|Myxococcales	28221|Deltaproteobacteria	S	Putative membrane peptidase family (DUF2324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
WZS2_k127_6003733_3	926569.ANT_16600	2.954e-83	295.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WZS2_k127_6003733_2	926569.ANT_16610	1.946e-86	290.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WZS2_k127_6003733_4	926569.ANT_16620	4.845e-70	245.0	COG0647@1|root,COG0647@2|Bacteria,2G6G5@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
WZS2_k127_6003733_6	926569.ANT_11660	1.321e-45	169.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WZS2_k127_6003733_0	926569.ANT_11670	5.63e-166	528.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WZS2_k127_6003733_1	926569.ANT_11680	3.075e-152	498.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
WZS2_k127_6003733_5	926569.ANT_11700	1.177e-57	206.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WZS2_k127_6003733_7	1298865.H978DRAFT_2664	6.057e-08	65.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,1RR88@1236|Gammaproteobacteria,465SN@72275|Alteromonadaceae	1236|Gammaproteobacteria	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DPPIV_N,PD40,Peptidase_S9
WZS2_k127_6028010_4	521460.Athe_0657	1.221e-68	246.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,24ACU@186801|Clostridia,42F5H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
WZS2_k127_6028010_5	867845.KI911784_gene3077	2.751e-64	228.0	COG5522@1|root,COG5522@2|Bacteria	2|Bacteria	S	Integral membrane protein (intg_mem_TP0381)	ywaF	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
WZS2_k127_6028010_6	1429916.X566_14925	2.628e-23	112.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,3JSZR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
WZS2_k127_6028010_0	926569.ANT_15490	4.473e-297	921.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WZS2_k127_6028010_1	207559.Dde_0341	2.373e-166	537.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2M8AC@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WZS2_k127_6028010_2	383372.Rcas_3272	3.094e-130	429.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
WZS2_k127_6028010_3	1173028.ANKO01000120_gene2770	1.113e-118	389.0	COG1052@1|root,COG1052@2|Bacteria,1G1BP@1117|Cyanobacteria,1HED5@1150|Oscillatoriales	1117|Cyanobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.26,1.20.1.1	ko:K00015,ko:K18916	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS2_k127_6155372_7	1131730.BAVI_16842	4.693e-10	61.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,4HH1R@91061|Bacilli,1ZICD@1386|Bacillus	91061|Bacilli	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
WZS2_k127_6155372_1	926569.ANT_05060	1.115e-216	679.0	COG2115@1|root,COG2115@2|Bacteria,2G688@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Xylose isomerase domain protein TIM barrel	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
WZS2_k127_6155372_0	926569.ANT_24910	3.435e-223	700.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WZS2_k127_6155372_6	485913.Krac_8904	1.069e-19	97.0	COG5433@1|root,COG5433@2|Bacteria,2G91G@200795|Chloroflexi	200795|Chloroflexi	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_assoc
WZS2_k127_6155372_5	671143.DAMO_2492	4.092e-21	100.0	COG5485@1|root,COG5485@2|Bacteria,2NRTW@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
WZS2_k127_6155372_4	1173024.KI912149_gene6381	1.728e-24	108.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
WZS2_k127_6155372_2	926569.ANT_02760	5.831e-47	182.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
WZS2_k127_6155372_8	1521187.JPIM01000023_gene764	0.0001766	53.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi,3768H@32061|Chloroflexia	32061|Chloroflexia	M	SH3, type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
WZS2_k127_6155372_3	1254432.SCE1572_05510	1.295e-32	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS2_k127_6175544_1	926569.ANT_19290	6.274e-66	239.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_6175544_0	926569.ANT_19280	2.955e-114	373.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WZS2_k127_6175544_2	383372.Rcas_1525	2.931e-46	177.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,375NK@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
WZS2_k127_6175544_3	1268072.PSAB_11170	8.912e-42	164.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,26S8K@186822|Paenibacillaceae	91061|Bacilli	S	DegV family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_6175544_4	1443122.Z958_01730	1.081e-24	108.0	COG1051@1|root,COG1051@2|Bacteria,1V5NQ@1239|Firmicutes,24PPQ@186801|Clostridia,36K3B@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS2_k127_6196807_8	292563.Cyast_0546	3.911e-33	145.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	WD40
WZS2_k127_6196807_2	113355.CM001775_gene2184	1.102e-230	724.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
WZS2_k127_6196807_3	926569.ANT_23780	1.358e-161	523.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi	200795|Chloroflexi	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
WZS2_k127_6196807_4	1128421.JAGA01000002_gene375	2.213e-83	285.0	COG2003@1|root,COG2003@2|Bacteria,2NPI9@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WZS2_k127_6196807_6	926569.ANT_14000	1.263e-57	206.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
WZS2_k127_6196807_1	926569.ANT_25420	3.986e-242	752.0	COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WZS2_k127_6196807_0	926569.ANT_25410	2.822e-294	910.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
WZS2_k127_6196807_5	316274.Haur_2262	6.302e-77	263.0	COG0745@1|root,COG0745@2|Bacteria,2G81R@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_620829_8	926569.ANT_23330	8.298e-19	87.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
WZS2_k127_620829_0	926569.ANT_23340	1.415e-179	575.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS2_k127_620829_2	926569.ANT_23350	5.65e-142	458.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WZS2_k127_620829_1	926569.ANT_23360	1.148e-168	542.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS2_k127_620829_6	357808.RoseRS_3785	1.992e-61	228.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi,374RW@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM cell division protein FtsW	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WZS2_k127_620829_4	926569.ANT_23380	5.12e-125	412.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WZS2_k127_620829_3	926569.ANT_23400	2.536e-129	432.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS2_k127_620829_5	926569.ANT_23420	4.982e-77	266.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WZS2_k127_6280385_0	926569.ANT_08350	3.224e-303	947.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WZS2_k127_6280385_1	926569.ANT_08340	1.312e-209	657.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
WZS2_k127_6280385_5	926569.ANT_08330	1.103e-66	231.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WZS2_k127_6280385_2	926569.ANT_08320	1.345e-197	622.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
WZS2_k127_6280385_6	926569.ANT_08310	1.42e-54	196.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
WZS2_k127_6280385_4	926569.ANT_08300	2.84e-92	305.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
WZS2_k127_6280385_7	575540.Isop_0670	2.549e-16	83.0	COG0838@1|root,COG0838@2|Bacteria,2J09T@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
WZS2_k127_6280385_3	926569.ANT_09200	9.229e-175	562.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS2_k127_6290255_8	926569.ANT_15290	2.546e-53	195.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_6290255_7	926569.ANT_15280	3.844e-68	237.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi	200795|Chloroflexi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WZS2_k127_6290255_0	926569.ANT_15270	6.817e-282	895.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi	200795|Chloroflexi	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WZS2_k127_6290255_9	1123252.ATZF01000016_gene1702	2.083e-43	170.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,27BEX@186824|Thermoactinomycetaceae	91061|Bacilli	S	Dihydroxyacetone kinase family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_6290255_11	926569.ANT_15260	2.797e-41	163.0	COG1307@1|root,COG1307@2|Bacteria,2G6P2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_6290255_1	926569.ANT_15250	4.173e-222	701.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
WZS2_k127_6290255_13	926569.ANT_15240	2.071e-37	146.0	COG1302@1|root,COG1302@2|Bacteria,2G76I@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WZS2_k127_6290255_17	926569.ANT_15230	1.799e-18	85.0	COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi	200795|Chloroflexi	J	ribosomal protein L28	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WZS2_k127_6290255_6	926569.ANT_15220	3.002e-75	259.0	COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WZS2_k127_6290255_4	926569.ANT_15210	4.977e-108	362.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WZS2_k127_6290255_14	867845.KI911784_gene2158	2.989e-34	144.0	COG1597@1|root,COG1597@2|Bacteria,2G70R@200795|Chloroflexi,375F4@32061|Chloroflexia	32061|Chloroflexia	I	diacylglycerol kinase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WZS2_k127_6290255_18	926569.ANT_15190	1.553e-15	83.0	2DTJR@1|root,33KPB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_6290255_12	926569.ANT_15180	2.369e-38	147.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
WZS2_k127_6290255_5	926569.ANT_14300	4.525e-105	344.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_6290255_2	926569.ANT_15110	1.515e-115	377.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_6290255_16	926569.ANT_15120	5.942e-22	98.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_6290255_10	926569.ANT_15130	2.646e-43	164.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
WZS2_k127_6290255_3	926569.ANT_15140	5.665e-115	387.0	COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
WZS2_k127_6290255_15	926569.ANT_15150	4.825e-25	106.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
WZS2_k127_6290426_3	926569.ANT_24820	2.929e-37	144.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WZS2_k127_6290426_1	926550.CLDAP_34690	3.816e-117	387.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WZS2_k127_6290426_5	926569.ANT_14090	7.361e-27	119.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
WZS2_k127_6290426_2	751945.Theos_2091	2.263e-46	176.0	COG0321@1|root,COG0321@2|Bacteria,1WIJ7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
WZS2_k127_6290426_0	926569.ANT_01830	0.0	1568.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WZS2_k127_6290426_4	926569.ANT_23620	3.818e-36	143.0	COG2839@1|root,COG2839@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF456)	yqgC	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
WZS2_k127_63157_4	661478.OP10G_3270	5.453e-73	251.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	neuC	GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016787,GO:0016798,GO:0044238,GO:0071704,GO:1901576	3.2.1.184,5.1.3.14	ko:K01791,ko:K18429	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R10187	RC00005,RC00288,RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
WZS2_k127_63157_2	682795.AciX8_1508	3.28e-122	402.0	COG2089@1|root,COG2089@2|Bacteria,3Y39R@57723|Acidobacteria	57723|Acidobacteria	M	PFAM N-acetylneuraminic acid synthase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NeuB
WZS2_k127_63157_3	1121440.AUMA01000011_gene2489	1.577e-97	324.0	COG1028@1|root,COG1028@2|Bacteria,1Q3GM@1224|Proteobacteria,42SZ6@68525|delta/epsilon subdivisions,2WP46@28221|Deltaproteobacteria,2MA7I@213115|Desulfovibrionales	28221|Deltaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WZS2_k127_63157_5	324925.Ppha_0533	1.156e-71	254.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ptmF	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WZS2_k127_63157_6	398767.Glov_0785	1.436e-64	231.0	COG0451@1|root,COG0451@2|Bacteria,1NUWT@1224|Proteobacteria,42Q7V@68525|delta/epsilon subdivisions	1224|Proteobacteria	GM	NAD dependent epimerase dehydratase family	-	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
WZS2_k127_63157_1	749222.Nitsa_2033	5.18e-152	500.0	COG0028@1|root,COG0028@2|Bacteria,1MYUS@1224|Proteobacteria,42QE8@68525|delta/epsilon subdivisions,2YNKA@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
WZS2_k127_63157_7	459349.CLOAM0646	8.821e-52	191.0	COG1018@1|root,COG1018@2|Bacteria	2|Bacteria	C	nitric oxide dioxygenase activity	-	-	1.14.12.17	ko:K02639,ko:K05916	ko00195,ko05132,map00195,map05132	-	-	-	ko00000,ko00001,ko00194,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
WZS2_k127_63157_0	459349.CLOAM0645	2.874e-181	576.0	COG0399@1|root,COG0399@2|Bacteria,2NQAE@2323|unclassified Bacteria	2|Bacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	rfbH	-	1.17.1.1,4.2.1.164	ko:K12452,ko:K13328	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00802	R03391,R03392,R08930	RC00230,RC00704	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
WZS2_k127_6511992_1	326427.Cagg_0078	4.103e-117	383.0	COG1472@1|root,COG1472@2|Bacteria,2G84T@200795|Chloroflexi,3759W@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WZS2_k127_6511992_2	1128421.JAGA01000002_gene1336	6.659e-72	252.0	COG2514@1|root,COG2514@2|Bacteria,2NRH9@2323|unclassified Bacteria	2|Bacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	CppA_C,Glyoxalase
WZS2_k127_6511992_0	926569.ANT_27120	3.937e-209	674.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
WZS2_k127_6511992_3	485916.Dtox_1611	9.751e-21	93.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
WZS2_k127_6559121_3	926569.ANT_30270	1.97e-30	123.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,2G75J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
WZS2_k127_6559121_1	926569.ANT_01740	2.458e-141	475.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
WZS2_k127_6559121_0	926569.ANT_01770	1.415e-155	500.0	COG0438@1|root,COG0438@2|Bacteria,2G6KX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
WZS2_k127_6559121_2	926569.ANT_16530	3.836e-86	295.0	COG2211@1|root,COG2211@2|Bacteria,2GA8Z@200795|Chloroflexi	200795|Chloroflexi	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_6642209_4	326427.Cagg_1507	3.594e-55	201.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
WZS2_k127_6642209_2	485913.Krac_10314	3.358e-62	227.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
WZS2_k127_6642209_1	926569.ANT_29120	1.555e-121	396.0	COG0348@1|root,COG0348@2|Bacteria,2G8SY@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
WZS2_k127_6642209_3	2325.TKV_c01900	7.519e-60	218.0	COG0348@1|root,COG0348@2|Bacteria,1V8RW@1239|Firmicutes,24JXS@186801|Clostridia,42GUZ@68295|Thermoanaerobacterales	186801|Clostridia	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_6642209_0	479434.Sthe_1490	1.626e-133	445.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS2_k127_6678724_4	926569.ANT_13330	3.194e-100	330.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS2_k127_6678724_6	926569.ANT_13320	2.198e-70	244.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc,RDD,Trans_reg_C,Yop-YscD_cpl
WZS2_k127_6678724_3	926569.ANT_13310	5.024e-112	376.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi	200795|Chloroflexi	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
WZS2_k127_6678724_0	926569.ANT_13300	1.266e-206	655.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
WZS2_k127_6678724_1	926550.CLDAP_19050	2.993e-181	578.0	COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
WZS2_k127_6678724_2	525904.Tter_0931	4.706e-138	449.0	COG0343@1|root,COG0343@2|Bacteria,2NNQS@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	iECW_1372.ECW_m0475,iWFL_1372.ECW_m0475	TGT
WZS2_k127_6678724_5	926569.ANT_13070	3.479e-86	293.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi	200795|Chloroflexi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WZS2_k127_6678826_0	926569.ANT_08410	1.722e-204	646.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
WZS2_k127_6678826_1	926569.ANT_08400	8.123e-199	642.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	200795|Chloroflexi	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
WZS2_k127_6678826_5	926569.ANT_08390	6.061e-34	133.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
WZS2_k127_6678826_4	1128421.JAGA01000002_gene147	3.811e-39	152.0	COG0839@1|root,COG0839@2|Bacteria,2NPUC@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	nuoJ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WZS2_k127_6678826_3	926569.ANT_08370	3.639e-78	265.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
WZS2_k127_6678826_2	926569.ANT_08360	9.618e-135	437.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WZS2_k127_6693212_1	926569.ANT_19940	6.49e-66	239.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
WZS2_k127_6693212_5	1382306.JNIM01000001_gene968	1.738e-16	85.0	COG1254@1|root,COG1254@2|Bacteria,2G728@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
WZS2_k127_6693212_6	314285.KT71_18836	1.611e-09	63.0	COG2963@1|root,COG2963@2|Bacteria,1N28U@1224|Proteobacteria,1S9BK@1236|Gammaproteobacteria,1JBP6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
WZS2_k127_6693212_0	485913.Krac_5551	1.192e-80	280.0	COG2801@1|root,COG2801@2|Bacteria,2G8GQ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
WZS2_k127_6693212_2	926569.ANT_06720	2.829e-33	135.0	COG3877@1|root,COG3877@2|Bacteria,2G734@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
WZS2_k127_6693212_7	1521187.JPIM01000039_gene486	7.732e-07	61.0	COG3595@1|root,COG3595@2|Bacteria,2G7DM@200795|Chloroflexi,375KV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WZS2_k127_6693212_4	926569.ANT_06730	2.207e-21	96.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_6740381_5	926569.ANT_00200	8.044e-43	159.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WZS2_k127_6740381_2	765420.OSCT_3029	1.769e-81	291.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
WZS2_k127_6740381_6	926569.ANT_29070	1.836e-34	137.0	COG0607@1|root,COG0607@2|Bacteria,2G71Z@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WZS2_k127_6740381_0	1499967.BAYZ01000006_gene5474	8.568e-147	471.0	COG0667@1|root,COG0667@2|Bacteria,2NPI2@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS2_k127_6740381_1	926550.CLDAP_37650	1.013e-127	413.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
WZS2_k127_6740381_8	1423724.BAMM01000014_gene1528	1.469e-06	60.0	COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,4HFV8@91061|Bacilli,3F5IH@33958|Lactobacillaceae	91061|Bacilli	V	Beta-lactamase enzyme family	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,zinc_ribbon_2
WZS2_k127_6740381_3	592015.HMPREF1705_01010	2.246e-71	248.0	COG1296@1|root,COG1296@2|Bacteria,3TBT2@508458|Synergistetes	508458|Synergistetes	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
WZS2_k127_6740381_7	485913.Krac_5263	1.234e-25	110.0	COG4392@1|root,COG4392@2|Bacteria,2G7HT@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
WZS2_k127_6740381_4	383372.Rcas_2787	8.262e-53	187.0	COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi,376VV@32061|Chloroflexia	32061|Chloroflexia	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WZS2_k127_6748855_0	926569.ANT_26670	1.7e-279	866.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WZS2_k127_6748855_3	926569.ANT_26660	1.752e-41	154.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WZS2_k127_6748855_1	926569.ANT_00860	1.077e-112	379.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
WZS2_k127_6748855_2	926569.ANT_00870	1.241e-93	321.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
WZS2_k127_6778132_2	566466.NOR53_2155	2.257e-32	129.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,1SANT@1236|Gammaproteobacteria,1J8PD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WZS2_k127_6778132_0	864051.BurJ1DRAFT_2685	1.384e-223	722.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
WZS2_k127_6778132_1	314285.KT71_18426	1.275e-167	539.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
WZS2_k127_6778132_3	926569.ANT_27650	4.102e-29	122.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS2_k127_6790158_4	82654.Pse7367_3029	4.326e-06	61.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria	2|Bacteria	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41
WZS2_k127_6790158_1	926569.ANT_16850	6.459e-126	439.0	29DKV@1|root,300IP@2|Bacteria,2G8H2@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_6790158_0	926569.ANT_12990	9.884e-151	492.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
WZS2_k127_6790158_3	457570.Nther_0811	6.902e-07	57.0	COG4047@1|root,COG4047@2|Bacteria,1VWCX@1239|Firmicutes,25191@186801|Clostridia	186801|Clostridia	L	oxidized base lesion DNA N-glycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_6790158_2	926569.ANT_21170	1.549e-18	88.0	COG4974@1|root,COG4974@2|Bacteria,2G8U5@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
WZS2_k127_680132_8	926569.ANT_18610	4.38e-70	246.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_680132_7	926569.ANT_02710	4.236e-70	246.0	COG1526@1|root,COG1526@2|Bacteria,2G74E@200795|Chloroflexi	200795|Chloroflexi	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
WZS2_k127_680132_4	880072.Desac_1072	1.655e-143	475.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
WZS2_k127_680132_3	926569.ANT_29920	3.784e-162	517.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WZS2_k127_680132_2	926569.ANT_29920	9.154e-260	810.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
WZS2_k127_680132_6	316274.Haur_3936	1.151e-111	374.0	COG0477@1|root,COG2223@1|root,COG2223@2|Bacteria,COG2814@2|Bacteria,2GA7I@200795|Chloroflexi,3780K@32061|Chloroflexia	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_680132_9	666685.R2APBS1_0025	3.056e-38	155.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,1RRSK@1236|Gammaproteobacteria,1X384@135614|Xanthomonadales	135614|Xanthomonadales	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WZS2_k127_680132_1	926569.ANT_14570	4.187e-295	927.0	COG1111@1|root,COG1205@1|root,COG1403@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
WZS2_k127_680132_0	926569.ANT_27410	0.0	1398.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WZS2_k127_680132_5	926569.ANT_04320	1.39e-113	374.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS2_k127_680132_10	926569.ANT_04330	1.307e-08	60.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WZS2_k127_682487_3	926569.ANT_18520	1.803e-65	227.0	COG0170@1|root,COG0170@2|Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_682487_6	1499967.BAYZ01000179_gene4623	4.581e-52	194.0	29FVD@1|root,302T2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_682487_5	926569.ANT_18530	4.329e-59	208.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi	200795|Chloroflexi	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WZS2_k127_682487_7	926569.ANT_12940	7.41e-52	200.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WZS2_k127_682487_4	867845.KI911784_gene2744	1.331e-59	217.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
WZS2_k127_682487_2	926569.ANT_11710	5.25e-100	337.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS2_k127_682487_0	1122223.KB890687_gene2974	1.515e-199	632.0	COG2939@1|root,COG2939@2|Bacteria,1WJMU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
WZS2_k127_682487_1	926569.ANT_14670	2.916e-129	429.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WZS2_k127_6875241_3	326427.Cagg_2198	1.566e-14	86.0	COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
WZS2_k127_6875241_0	37659.JNLN01000001_gene1254	1.93e-97	341.0	COG1131@1|root,COG1131@2|Bacteria,1TQTX@1239|Firmicutes,249W1@186801|Clostridia,36FN8@31979|Clostridiaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_6875241_1	1499689.CCNN01000009_gene2814	7.274e-73	254.0	COG0842@1|root,COG0842@2|Bacteria,1TQ9K@1239|Firmicutes,24C8W@186801|Clostridia,36ID2@31979|Clostridiaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
WZS2_k127_6875241_2	1227454.C446_04245	6.044e-41	161.0	COG1266@1|root,arCOG02768@2157|Archaea,2XZ3X@28890|Euryarchaeota,23WZT@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WZS2_k127_6887909_0	926550.CLDAP_05130	0.0	1067.0	COG3250@1|root,COG3250@2|Bacteria,2G5R6@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
WZS2_k127_6887909_7	1347392.CCEZ01000044_gene630	7.154e-10	66.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia,36HYR@31979|Clostridiaceae	186801|Clostridia	K	PFAM Transcription factor CarD	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
WZS2_k127_6887909_6	1121091.AUMP01000003_gene2690	3.666e-36	143.0	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli	91061|Bacilli	K	Histone acetyltransferase HPA2 and related acetyltransferases	yycN	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_6887909_4	1122169.AREN01000010_gene2539	1.642e-87	295.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria,1JCVM@118969|Legionellales	118969|Legionellales	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
WZS2_k127_6887909_5	42256.RradSPS_2107	2.235e-85	291.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4CU2K@84995|Rubrobacteria	84995|Rubrobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
WZS2_k127_6887909_3	479434.Sthe_0597	1.316e-118	397.0	COG2905@1|root,COG4191@1|root,COG2905@2|Bacteria,COG4191@2|Bacteria,2G807@200795|Chloroflexi	200795|Chloroflexi	H	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
WZS2_k127_6887909_2	926560.KE387023_gene1698	3.92e-186	597.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1WM1W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KOT	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Response_reg
WZS2_k127_6887909_1	926550.CLDAP_31970	0.0	1047.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
WZS2_k127_697354_9	926550.CLDAP_38560	2.206e-43	163.0	COG1764@1|root,COG1764@2|Bacteria,2G6W8@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
WZS2_k127_697354_8	485913.Krac_10657	4.788e-55	199.0	2F1C8@1|root,33UD3@2|Bacteria,2G8D9@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS2_k127_697354_6	485913.Krac_5625	3.832e-67	239.0	COG0400@1|root,COG0400@2|Bacteria,2G8M6@200795|Chloroflexi	200795|Chloroflexi	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
WZS2_k127_697354_11	756499.Desde_2107	9.488e-32	128.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,2670K@186807|Peptococcaceae	186801|Clostridia	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WZS2_k127_697354_2	926550.CLDAP_22390	2.835e-122	404.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WZS2_k127_697354_5	926569.ANT_09940	5.28e-72	247.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi	200795|Chloroflexi	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
WZS2_k127_697354_1	926569.ANT_09930	2.33e-128	425.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
WZS2_k127_697354_3	926569.ANT_09920	8.764e-97	327.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_697354_4	926569.ANT_09910	2.907e-83	284.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WZS2_k127_697354_7	926569.ANT_09900	1.76e-63	225.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi	200795|Chloroflexi	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WZS2_k127_697354_0	926569.ANT_09890	4.281e-224	720.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WZS2_k127_697354_10	926569.ANT_21020	1.56e-42	162.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS2_k127_7037351_0	1501230.ET33_02970	2.822e-289	909.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
WZS2_k127_7037351_3	926569.ANT_28350	6.064e-32	128.0	COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Stage V sporulation protein S	-	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
WZS2_k127_7037351_2	90814.KL370891_gene615	1.912e-34	136.0	2C3VI@1|root,33N3E@2|Bacteria,1NESF@1224|Proteobacteria,1STIY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_7037351_1	326427.Cagg_2222	1.66e-65	225.0	COG1012@1|root,COG1012@2|Bacteria,2G5JE@200795|Chloroflexi,375BH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
WZS2_k127_7049336_3	926569.ANT_06590	2.638e-117	381.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
WZS2_k127_7049336_6	429009.Adeg_1649	1.614e-102	347.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,42EPQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
WZS2_k127_7049336_0	926569.ANT_06750	2.354e-209	657.0	COG1207@1|root,COG1207@2|Bacteria,2G7KV@200795|Chloroflexi	200795|Chloroflexi	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WZS2_k127_7049336_11	926569.ANT_03770	1.875e-55	206.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
WZS2_k127_7049336_5	926569.ANT_06770	6.711e-112	368.0	COG2267@1|root,COG2267@2|Bacteria,2G761@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS2_k127_7049336_8	926569.ANT_06780	1.671e-92	306.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
WZS2_k127_7049336_4	926569.ANT_06790	1.671e-112	369.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
WZS2_k127_7049336_9	926569.ANT_11070	9.33e-88	301.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WZS2_k127_7049336_1	926569.ANT_11080	2.102e-169	545.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WZS2_k127_7049336_10	926550.CLDAP_13320	6.271e-71	257.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS2_k127_7049336_2	926569.ANT_07740	1.29e-134	441.0	COG0577@1|root,COG0577@2|Bacteria,2G6MK@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS2_k127_7049336_7	926569.ANT_07730	2.667e-102	350.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF4114,DUF4157
WZS2_k127_7131139_2	485913.Krac_10552	1.584e-25	109.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WZS2_k127_7131139_0	1128421.JAGA01000002_gene1860	1.569e-136	448.0	COG2124@1|root,COG2124@2|Bacteria	2|Bacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	KR,p450
WZS2_k127_7131139_1	485913.Krac_2634	1.277e-34	149.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS
WZS2_k127_7131139_3	1265313.HRUBRA_01008	5.095e-12	78.0	COG1957@1|root,COG5042@1|root,COG1957@2|Bacteria,COG5042@2|Bacteria,1MUIW@1224|Proteobacteria,1RSCY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the IUNH family	rihA	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0047405,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_0645,iECSE_1348.ECSE_0721,iEcE24377_1341.EcE24377A_0679,iSbBS512_1146.SbBS512_E0598	IU_nuc_hydro
WZS2_k127_7160341_3	926569.ANT_15960	1.519e-26	109.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
WZS2_k127_7160341_2	926569.ANT_15970	1.76e-39	151.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WZS2_k127_7160341_1	926569.ANT_15980	8.06e-82	283.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_7160341_0	926569.ANT_15990	0.0	1078.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WZS2_k127_7179126_7	1035191.HMPREF0185_00567	1.996e-13	74.0	COG2364@1|root,COG2364@2|Bacteria,1QZWW@1224|Proteobacteria,2U6M8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	YitT_membrane
WZS2_k127_7179126_0	926569.ANT_23480	0.0	1281.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
WZS2_k127_7179126_2	926569.ANT_23470	1.425e-65	226.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi	200795|Chloroflexi	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WZS2_k127_7179126_5	502025.Hoch_3589	7.836e-44	166.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,42RY9@68525|delta/epsilon subdivisions,2WW61@28221|Deltaproteobacteria,2Z2RX@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WZS2_k127_7179126_1	349521.HCH_00321	7.309e-80	275.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,1RRC5@1236|Gammaproteobacteria,1XJZQ@135619|Oceanospirillales	135619|Oceanospirillales	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
WZS2_k127_7179126_6	1122165.AUHS01000011_gene2632	2.05e-19	103.0	COG0596@1|root,COG0596@2|Bacteria,1N3G3@1224|Proteobacteria,1S50R@1236|Gammaproteobacteria,1JGJE@118969|Legionellales	118969|Legionellales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS2_k127_7179126_4	1128421.JAGA01000002_gene1425	5.039e-46	188.0	COG0791@1|root,COG0791@2|Bacteria,2NREJ@2323|unclassified Bacteria	2|Bacteria	M	NlpC/P60 family	ykfC	-	3.4.14.13	ko:K20742,ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
WZS2_k127_7179126_3	316274.Haur_3591	5.686e-56	205.0	COG4948@1|root,COG4948@2|Bacteria,2G882@200795|Chloroflexi,3757P@32061|Chloroflexia	2|Bacteria	M	mandelate racemase muconate lactonizing	ycjG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	iEC042_1314.EC042_1441,iECUMN_1333.ECUMN_1620	MR_MLE_C,MR_MLE_N
WZS2_k127_7249865_2	926569.ANT_08380	3.878e-33	131.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
WZS2_k127_7249865_1	926569.ANT_08370	5.569e-77	260.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
WZS2_k127_7249865_0	926569.ANT_08360	2.947e-148	475.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
WZS2_k127_7253709_6	867845.KI911784_gene1365	9.558e-42	166.0	COG0823@1|root,COG3693@1|root,COG0823@2|Bacteria,COG3693@2|Bacteria,2GA75@200795|Chloroflexi,37735@32061|Chloroflexia	32061|Chloroflexia	U	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_7253709_2	357808.RoseRS_4078	1.351e-132	430.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WZS2_k127_7253709_4	56780.SYN_01129	4.831e-101	334.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WJEC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	JM	PFAM Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
WZS2_k127_7253709_1	926569.ANT_09480	2.984e-143	464.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WZS2_k127_7253709_5	926569.ANT_09470	1.285e-96	326.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi	200795|Chloroflexi	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
WZS2_k127_7253709_3	926569.ANT_09460	2.893e-102	346.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
WZS2_k127_7253709_0	903818.KI912268_gene3105	8.45e-158	505.0	COG0787@1|root,COG0787@2|Bacteria,3Y2U3@57723|Acidobacteria	57723|Acidobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WZS2_k127_7255265_8	72019.SARC_01424T0	2.996e-32	127.0	COG0138@1|root,KOG2555@2759|Eukaryota,38H8U@33154|Opisthokonta	33154|Opisthokonta	F	IMP cyclohydrolase activity	ATIC	GO:0000003,GO:0003006,GO:0003360,GO:0003674,GO:0003824,GO:0003937,GO:0004643,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006760,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007049,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0009058,GO:0009060,GO:0009108,GO:0009116,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009235,GO:0009259,GO:0009260,GO:0009396,GO:0009611,GO:0009653,GO:0009987,GO:0010035,GO:0015980,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0019953,GO:0021537,GO:0021543,GO:0021549,GO:0021987,GO:0022037,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0030435,GO:0030437,GO:0030900,GO:0030902,GO:0031099,GO:0031100,GO:0032501,GO:0032502,GO:0032505,GO:0033013,GO:0034293,GO:0034641,GO:0034654,GO:0042060,GO:0042221,GO:0042398,GO:0042558,GO:0042559,GO:0042802,GO:0042803,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043934,GO:0043935,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0045333,GO:0046040,GO:0046390,GO:0046394,GO:0046452,GO:0046483,GO:0046653,GO:0046654,GO:0046983,GO:0048468,GO:0048513,GO:0048646,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051186,GO:0051188,GO:0051321,GO:0051704,GO:0055086,GO:0055114,GO:0060322,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903046	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WZS2_k127_7255265_2	573061.Clocel_3660	1.462e-166	532.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,36DHZ@31979|Clostridiaceae	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
WZS2_k127_7255265_0	1313172.YM304_23650	6.181e-201	636.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
WZS2_k127_7255265_6	926569.ANT_08510	5.822e-63	223.0	COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
WZS2_k127_7255265_5	765420.OSCT_1336	2.643e-98	328.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi,375AJ@32061|Chloroflexia	32061|Chloroflexia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS2_k127_7255265_7	926569.ANT_08490	1.682e-40	155.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WZS2_k127_7255265_9	65093.PCC7418_0145	6.571e-08	61.0	2ETGP@1|root,33M0J@2|Bacteria,1GAIU@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_7255265_1	926550.CLDAP_27540	9.129e-181	581.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WZS2_k127_7255265_3	926569.ANT_09430	4.192e-147	471.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
WZS2_k127_7255265_4	926569.ANT_31030	3.684e-109	363.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WZS2_k127_7270361_1	926569.ANT_30000	1.952e-282	889.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
WZS2_k127_7270361_0	926569.ANT_04080	2.12e-316	978.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi	200795|Chloroflexi	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
WZS2_k127_7270361_2	926550.CLDAP_07480	5.275e-95	316.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS2_k127_7284620_2	765420.OSCT_2960	1.155e-94	325.0	COG2890@1|root,COG2890@2|Bacteria,2G8FJ@200795|Chloroflexi,3768E@32061|Chloroflexia	32061|Chloroflexia	J	RNA cap guanine-N2 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_15
WZS2_k127_7284620_0	926569.ANT_19090	6.36e-176	561.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi	200795|Chloroflexi	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WZS2_k127_7284620_1	926569.ANT_19100	1.343e-137	445.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
WZS2_k127_7284620_6	928724.SacglDRAFT_02257	6.266e-08	65.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,2GMNT@201174|Actinobacteria,4DYP4@85010|Pseudonocardiales	201174|Actinobacteria	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
WZS2_k127_7284620_5	580327.Tthe_0478	1.053e-13	80.0	COG1388@1|root,COG1388@2|Bacteria,1UHZC@1239|Firmicutes,25E80@186801|Clostridia,42FCR@68295|Thermoanaerobacterales	186801|Clostridia	M	Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,PG_binding_1
WZS2_k127_7284620_3	357808.RoseRS_1903	6.174e-55	209.0	COG2211@1|root,COG2211@2|Bacteria,2G6B9@200795|Chloroflexi,3767E@32061|Chloroflexia	32061|Chloroflexia	G	major facilitator superfamily MFS_1	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
WZS2_k127_7284620_4	926550.CLDAP_19150	4.478e-33	132.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
WZS2_k127_7315410_2	880073.Calab_1013	6.025e-170	549.0	COG2132@1|root,COG2132@2|Bacteria,2NP9C@2323|unclassified Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WZS2_k127_7315410_4	292459.STH2407	4.506e-69	239.0	COG2259@1|root,COG2259@2|Bacteria,1V38Q@1239|Firmicutes,25DF1@186801|Clostridia	186801|Clostridia	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
WZS2_k127_7315410_6	153948.NAL212_0227	8.775e-60	213.0	COG0500@1|root,COG2226@2|Bacteria,1PE85@1224|Proteobacteria,2W92M@28216|Betaproteobacteria,373FB@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS2_k127_7315410_9	1121930.AQXG01000048_gene25	3.47e-41	158.0	COG4633@1|root,COG4633@2|Bacteria,4P6N2@976|Bacteroidetes	976|Bacteroidetes	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
WZS2_k127_7315410_0	644966.Tmar_1561	0.0	1028.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3WCCN@538999|Clostridiales incertae sedis	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS2_k127_7315410_1	545243.BAEV01000010_gene1093	1.282e-201	637.0	COG0348@1|root,COG0348@2|Bacteria,1U9JQ@1239|Firmicutes,24ADI@186801|Clostridia,36F22@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
WZS2_k127_7315410_14	545243.BAEV01000010_gene1092	0.0009196	50.0	29PH6@1|root,30AFB@2|Bacteria,1W26W@1239|Firmicutes,249DA@186801|Clostridia,36GEV@31979|Clostridiaceae	186801|Clostridia	S	YtkA-like	-	-	-	-	-	-	-	-	-	-	-	-	YtkA
WZS2_k127_7315410_12	869210.Marky_1036	3.103e-18	85.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
WZS2_k127_7315410_10	926569.ANT_18490	3.755e-36	147.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
WZS2_k127_7315410_11	644966.Tmar_1592	5.63e-26	112.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069,Lactamase_B,Rhodanese
WZS2_k127_7315410_8	1128421.JAGA01000002_gene1307	3.993e-42	176.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8
WZS2_k127_7315410_5	1128421.JAGA01000002_gene1308	8.371e-60	215.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_7315410_7	926550.CLDAP_14450	8.344e-44	168.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
WZS2_k127_7315410_13	404589.Anae109_1223	0.0004608	48.0	COG5456@1|root,COG5456@2|Bacteria,1R398@1224|Proteobacteria,4338A@68525|delta/epsilon subdivisions,2WYHW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
WZS2_k127_7315410_3	643473.KB235932_gene5057	1.414e-107	357.0	COG2132@1|root,COG2132@2|Bacteria,1G3J9@1117|Cyanobacteria,1HT4K@1161|Nostocales	1117|Cyanobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
WZS2_k127_7333111_0	926569.ANT_15910	2.692e-153	490.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
WZS2_k127_7333111_7	768704.Desmer_3607	2.304e-17	96.0	COG3409@1|root,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,24965@186801|Clostridia,261US@186807|Peptococcaceae	186801|Clostridia	M	peptidoglycan-binding domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60,PG_binding_1
WZS2_k127_7333111_3	926569.ANT_15920	1.791e-80	277.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
WZS2_k127_7333111_2	926569.ANT_15930	6.001e-96	322.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
WZS2_k127_7333111_4	926569.ANT_15940	2.399e-75	265.0	COG1577@1|root,COG1577@2|Bacteria,2G6DY@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
WZS2_k127_7333111_6	106370.Francci3_2342	1.676e-34	146.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13,3.6.1.55,3.6.1.67	ko:K01515,ko:K03574,ko:K08310	ko00230,ko00790,map00230,map00790	M00126	R01054,R04638	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	NUDIX
WZS2_k127_7333111_5	926569.ANT_15950	2.631e-66	235.0	COG1608@1|root,COG1608@2|Bacteria,2G6TH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aspartate glutamate uridylate kinase	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS2_k127_7333111_1	926569.ANT_15960	1.289e-151	484.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
WZS2_k127_7355216_1	926569.ANT_22610	4.895e-124	406.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WZS2_k127_7355216_2	926569.ANT_22600	2.764e-76	269.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
WZS2_k127_7355216_5	869209.Tresu_1338	5.404e-16	82.0	COG2348@1|root,COG2348@2|Bacteria,2J58H@203691|Spirochaetes	203691|Spirochaetes	V	Methicillin resistance protein	femA	-	-	-	-	-	-	-	-	-	-	-	FemAB
WZS2_k127_7355216_0	768671.ThimaDRAFT_1778	8.105e-132	428.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,1RMYP@1236|Gammaproteobacteria,1X0CX@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.25	ko:K17950	ko00270,map00270	-	R07634	RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
WZS2_k127_7355216_3	485913.Krac_10749	6.368e-52	196.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
WZS2_k127_7355216_4	485913.Krac_7740	2.032e-30	129.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
WZS2_k127_7359776_7	926569.ANT_01320	4.836e-14	73.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi	200795|Chloroflexi	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
WZS2_k127_7359776_11	383372.Rcas_4147	6.431e-07	60.0	COG1388@1|root,COG1388@2|Bacteria,2G95J@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_C39_2
WZS2_k127_7359776_10	1033806.HTIA_p2886	3.604e-07	61.0	COG2333@1|root,arCOG08231@1|root,arCOG03009@2157|Archaea,arCOG08231@2157|Archaea,2XSXI@28890|Euryarchaeota,23SH8@183963|Halobacteria	183963|Halobacteria	S	hydrolase (metallo-beta-lactamase superfamily)	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	LTD,Lactamase_B
WZS2_k127_7359776_9	161934.XP_010683968.1	4.846e-13	75.0	KOG0568@1|root,KOG0568@2759|Eukaryota,37PDH@33090|Viridiplantae,3GEYN@35493|Streptophyta	35493|Streptophyta	O	DnaJ homolog, subfamily C, member	-	-	-	ko:K19373	-	-	-	-	ko00000,ko03110	-	-	-	DUF1992
WZS2_k127_7359776_8	682795.AciX8_4439	1.388e-13	76.0	COG0537@1|root,COG0537@2|Bacteria,3Y542@57723|Acidobacteria,2JJT8@204432|Acidobacteriia	204432|Acidobacteriia	FG	PFAM Histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
WZS2_k127_7359776_2	357808.RoseRS_3033	1.581e-84	295.0	COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi,3771W@32061|Chloroflexia	32061|Chloroflexia	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
WZS2_k127_7359776_4	926550.CLDAP_22130	7.843e-62	216.0	COG1051@1|root,COG1051@2|Bacteria,2G7HA@200795|Chloroflexi	200795|Chloroflexi	F	PFAM NUDIX hydrolase	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
WZS2_k127_7359776_3	926569.ANT_02760	2.313e-64	229.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
WZS2_k127_7359776_1	1173026.Glo7428_2034	5.465e-100	337.0	COG3268@1|root,COG3268@2|Bacteria,1G3XG@1117|Cyanobacteria	1117|Cyanobacteria	S	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
WZS2_k127_7359776_5	401526.TcarDRAFT_0025	1.756e-49	181.0	COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,4H4CB@909932|Negativicutes	909932|Negativicutes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
WZS2_k127_7359776_0	926569.ANT_00490	6.012e-180	574.0	COG0433@1|root,COG0433@2|Bacteria,2G62A@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87,HAS-barrel
WZS2_k127_7369336_5	1121324.CLIT_10c04120	7.229e-81	280.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,25SV4@186804|Peptostreptococcaceae	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
WZS2_k127_7369336_3	1449126.JQKL01000004_gene567	4.822e-91	310.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,268KP@186813|unclassified Clostridiales	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
WZS2_k127_7369336_4	1444309.JAQG01000100_gene4709	2.526e-86	308.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,26QGU@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	dppE	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WZS2_k127_7369336_0	926550.CLDAP_11110	6.158e-155	494.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS2_k127_7369336_1	926550.CLDAP_11120	1.966e-134	437.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS2_k127_7369336_2	926569.ANT_02800	3.904e-124	404.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
WZS2_k127_7369336_6	926569.ANT_02790	5.28e-56	200.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
WZS2_k127_7411785_1	926569.ANT_23610	5.402e-197	621.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WZS2_k127_7411785_2	926550.CLDAP_36110	3.194e-117	405.0	COG0810@1|root,COG2152@1|root,COG3291@1|root,COG0810@2|Bacteria,COG2152@2|Bacteria,COG3291@2|Bacteria,2G86G@200795|Chloroflexi	200795|Chloroflexi	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WZS2_k127_7411785_4	118161.KB235922_gene2849	3.914e-47	193.0	COG3204@1|root,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_4,Cadherin,Exo_endo_phos,HemolysinCabind,LTD,Laminin_G_3,PA14,SNase,SdiA-regulated
WZS2_k127_7411785_6	926569.ANT_30850	1.712e-27	113.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nfuA	-	-	-	-	-	-	-	-	-	-	-	NifU
WZS2_k127_7411785_7	926569.ANT_30840	2.46e-19	94.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Fer4_7,HTH_Crp_2,cNMP_binding
WZS2_k127_7411785_0	926569.ANT_04140	0.0	1318.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WZS2_k127_7411785_3	926569.ANT_04150	3.882e-57	211.0	COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_7411785_5	926569.ANT_04160	9.699e-29	119.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
WZS2_k127_7476324_4	591159.ACEZ01000196_gene2754	3.581e-40	154.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria	201174|Actinobacteria	E	decarboxylase	-	-	1.14.13.9,4.1.1.105,4.1.1.28	ko:K00486,ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00038,M00042	R00685,R00699,R00736,R01960,R02080,R02701,R04909	RC00046,RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
WZS2_k127_7476324_1	926569.ANT_01810	2.27e-109	367.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WZS2_k127_7476324_0	926569.ANT_14840	2.433e-291	910.0	COG2414@1|root,COG2414@2|Bacteria	2|Bacteria	C	aldehyde ferredoxin oxidoreductase activity	-	-	1.2.7.5,1.2.7.6	ko:K03738,ko:K11389	ko00010,ko00030,ko01100,ko01120,ko01200,ko01230,map00010,map00030,map01100,map01120,map01200,map01230	M00001,M00002,M00309	R07159,R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WZS2_k127_7476324_3	1385513.N780_19690	6.521e-50	205.0	COG2374@1|root,COG2374@2|Bacteria,1VKCH@1239|Firmicutes,4IS68@91061|Bacilli,2Y9FW@289201|Pontibacillus	91061|Bacilli	S	endonuclease exonuclease phosphatase	XK27_02140	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CHB_HEX_C_1,Exo_endo_phos,Fn3_assoc,Gram_pos_anchor,LTD,SLH
WZS2_k127_7476324_6	1121940.AUDZ01000018_gene440	1.974e-05	56.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,1XI3S@135619|Oceanospirillales	135619|Oceanospirillales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
WZS2_k127_7476324_2	215803.DB30_1101	2.071e-57	213.0	2DFQT@1|root,32U5Y@2|Bacteria,1MZ5S@1224|Proteobacteria,42UEJ@68525|delta/epsilon subdivisions,2WQUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_7476324_5	926569.ANT_03400	1.168e-35	140.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_7586554_2	926569.ANT_08710	1.49e-73	254.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WZS2_k127_7586554_4	926569.ANT_16060	5.718e-53	192.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
WZS2_k127_7586554_7	28072.Nos7524_4267	8.339e-29	124.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1G59V@1117|Cyanobacteria,1HMS6@1161|Nostocales	1117|Cyanobacteria	K	protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_20,HTH_5
WZS2_k127_7586554_3	926569.ANT_26460	2.01e-71	249.0	COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WZS2_k127_7586554_5	1150474.JQJI01000002_gene1181	1.2e-41	162.0	COG2110@1|root,COG2110@2|Bacteria,2GD2K@200918|Thermotogae	200918|Thermotogae	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
WZS2_k127_7586554_6	926569.ANT_00590	1.381e-41	156.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WZS2_k127_7586554_8	926569.ANT_00600	3.248e-26	109.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WZS2_k127_7586554_1	926569.ANT_02480	4.717e-76	259.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WZS2_k127_7586554_0	383372.Rcas_0349	2.697e-279	871.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi,374UF@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
WZS2_k127_7635418_3	1232410.KI421424_gene1592	6.065e-61	218.0	COG1215@1|root,COG2344@1|root,COG1215@2|Bacteria,COG2344@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,43S6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WZS2_k127_7635418_9	1379698.RBG1_1C00001G1895	7.149e-11	74.0	COG0438@1|root,COG0438@2|Bacteria,2NQAY@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WZS2_k127_7635418_6	926569.ANT_28020	1.556e-47	182.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_4
WZS2_k127_7635418_0	518766.Rmar_0497	9.389e-167	541.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,1FKD5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
WZS2_k127_7635418_4	1121405.dsmv_3084	3.379e-51	196.0	COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria,2MHNH@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_7635418_8	926569.ANT_00160	3.238e-37	147.0	28U8H@1|root,2ZGE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_7635418_1	926569.ANT_28730	2.969e-112	378.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS2_k127_7635418_2	926569.ANT_28720	5.085e-103	340.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_7635418_5	926569.ANT_18950	2.204e-48	176.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WZS2_k127_7635418_7	926569.ANT_18960	1.677e-47	176.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WZS2_k127_7635418_10	926569.ANT_18970	4.453e-10	61.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WZS2_k127_7641466_3	926569.ANT_20880	8.864e-06	48.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
WZS2_k127_7641466_1	1042163.BRLA_c033410	9.323e-151	487.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,26QJA@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WZS2_k127_7641466_2	926550.CLDAP_06710	1.154e-119	394.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WZS2_k127_7641466_0	926569.ANT_05370	4.148e-183	582.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
WZS2_k127_767473_1	118166.JH976537_gene4691	3.044e-208	652.0	COG0296@1|root,COG0296@2|Bacteria,1G4X2@1117|Cyanobacteria,1H8Y0@1150|Oscillatoriales	1117|Cyanobacteria	G	Alpha amylase, C-terminal all-beta domain	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
WZS2_k127_767473_17	234267.Acid_0752	4.098e-29	121.0	COG0517@1|root,COG0517@2|Bacteria,3Y8IB@57723|Acidobacteria	57723|Acidobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WZS2_k127_767473_15	1499967.BAYZ01000048_gene2701	1.16e-31	129.0	2DMDR@1|root,32QSY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1475)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1475
WZS2_k127_767473_11	1128421.JAGA01000002_gene202	3.816e-57	210.0	COG1307@1|root,COG1307@2|Bacteria,2NQTE@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised protein, DegV family COG1307	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_767473_14	56780.SYN_03642	5.236e-43	159.0	COG1225@1|root,COG1225@2|Bacteria,1P69S@1224|Proteobacteria,432W3@68525|delta/epsilon subdivisions,2WXMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	AhpC/TSA family	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
WZS2_k127_767473_20	1321778.HMPREF1982_02941	0.0004688	46.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
WZS2_k127_767473_7	926550.CLDAP_28300	4.151e-98	340.0	COG2267@1|root,COG2267@2|Bacteria,2G6KF@200795|Chloroflexi	200795|Chloroflexi	I	Alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
WZS2_k127_767473_9	926550.CLDAP_15070	1.464e-64	234.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	M1-693	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
WZS2_k127_767473_0	272134.KB731324_gene5179	1.329e-287	908.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria,1H7PF@1150|Oscillatoriales	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
WZS2_k127_767473_4	1521187.JPIM01000020_gene212	1.159e-141	464.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
WZS2_k127_767473_2	926550.CLDAP_29020	1.653e-194	618.0	COG1233@1|root,COG1233@2|Bacteria,2G5U1@200795|Chloroflexi	200795|Chloroflexi	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WZS2_k127_767473_13	926550.CLDAP_29030	4.838e-53	190.0	COG4276@1|root,COG4276@2|Bacteria,2G9EV@200795|Chloroflexi	200795|Chloroflexi	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_767473_5	290399.Arth_0946	1.689e-129	419.0	COG3752@1|root,COG3752@2|Bacteria,2GNX1@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WZS2_k127_767473_6	926550.CLDAP_29050	1.226e-98	336.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, MerR	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
WZS2_k127_767473_3	589865.DaAHT2_1405	2.074e-171	545.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MM6V@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WZS2_k127_767473_18	1035195.HMPREF9997_01564	1.021e-17	98.0	COG5113@1|root,COG3236@2|Bacteria,2HPWN@201174|Actinobacteria,22QB7@1653|Corynebacteriaceae	201174|Actinobacteria	O	Domain of unknown function (DUF1768)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1768
WZS2_k127_767473_8	1278073.MYSTI_01806	3.381e-72	267.0	2BDMM@1|root,327B4@2|Bacteria,1QNU7@1224|Proteobacteria,43E6R@68525|delta/epsilon subdivisions,2WZVT@28221|Deltaproteobacteria,2Z2UR@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_767473_12	1280390.CBQR020000141_gene3502	2.957e-55	202.0	COG2746@1|root,COG2746@2|Bacteria,1TT5E@1239|Firmicutes,4HI7Z@91061|Bacilli,26SJ7@186822|Paenibacillaceae	91061|Bacilli	V	aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
WZS2_k127_767473_10	926550.CLDAP_06980	2.142e-57	205.0	COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WZS2_k127_767473_16	926550.CLDAP_06970	1.46e-29	119.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
WZS2_k127_7785977_2	880073.Calab_2452	1.444e-28	115.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WZS2_k127_7785977_0	566466.NOR53_798	1.304e-114	382.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1J96D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Rhodanese,Sulf_transp
WZS2_k127_7785977_3	593750.Metfor_2807	8.78e-05	54.0	COG0515@1|root,arCOG03682@2157|Archaea	2157|Archaea	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
WZS2_k127_7785977_1	926569.ANT_17030	2.606e-80	277.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yicL_1	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
WZS2_k127_7962284_3	926569.ANT_12920	4.138e-43	166.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
WZS2_k127_7962284_2	926569.ANT_12910	3.084e-62	222.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi	200795|Chloroflexi	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WZS2_k127_7962284_4	1386089.N865_04180	6.048e-43	172.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
WZS2_k127_7962284_1	502025.Hoch_3943	7.513e-111	368.0	COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,43ASD@68525|delta/epsilon subdivisions,2X66J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
WZS2_k127_7962284_0	926569.ANT_12970	2.885e-125	411.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WZS2_k127_8016615_3	211114.JOEF01000001_gene7240	2.973e-74	254.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4E068@85010|Pseudonocardiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_8016615_0	1380347.JNII01000006_gene1824	1.78e-147	491.0	COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria,4EX5G@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WZS2_k127_8016615_7	1449044.JMLE01000040_gene1826	6.149e-24	109.0	2F92T@1|root,341EE@2|Bacteria,2GPMN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8016615_5	926549.KI421517_gene1458	1.533e-65	234.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,47PEN@768503|Cytophagia	976|Bacteroidetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
WZS2_k127_8016615_4	479434.Sthe_0104	5.062e-72	255.0	COG4447@1|root,COG4447@2|Bacteria,2G8DW@200795|Chloroflexi,27YX3@189775|Thermomicrobia	189775|Thermomicrobia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8016615_1	1380600.AUYN01000001_gene2482	1.631e-80	273.0	28JPN@1|root,2Z9FN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	H2O2_YaaD
WZS2_k127_8016615_6	1266925.JHVX01000007_gene2357	3.655e-50	182.0	COG0343@1|root,COG0343@2|Bacteria,1P27H@1224|Proteobacteria	1224|Proteobacteria	J	queuine tRNA-ribosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8054514_1	357808.RoseRS_4511	1.786e-87	292.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
WZS2_k127_8054514_0	357808.RoseRS_4510	1.591e-186	595.0	COG0370@1|root,COG0370@2|Bacteria,2GBTA@200795|Chloroflexi,37667@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
WZS2_k127_8054514_2	945713.IALB_1132	3.288e-52	189.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
WZS2_k127_8054514_5	1480694.DC28_04730	1.357e-18	87.0	COG2211@1|root,COG2211@2|Bacteria,2J6P4@203691|Spirochaetes	203691|Spirochaetes	G	transporter	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WZS2_k127_8054514_3	1122925.KB895378_gene2633	3.94e-28	124.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,26TNF@186822|Paenibacillaceae	91061|Bacilli	C	NAD(P)H-dependent oxidoreductase	-	-	1.5.1.39	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	-	R05705,R05706,R08014,R08017,R08042	RC00126,RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
WZS2_k127_8054514_4	349520.PPE_02465	5.649e-20	104.0	COG4447@1|root,COG4447@2|Bacteria,1VI42@1239|Firmicutes,4HNYH@91061|Bacilli,26QUW@186822|Paenibacillaceae	91061|Bacilli	S	protein related to plant photosystem II stability assembly factor	sorCs3	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
WZS2_k127_8054514_6	761193.Runsl_5326	4.596e-08	56.0	COG3385@1|root,COG3385@2|Bacteria,4P02Y@976|Bacteroidetes,47TUA@768503|Cytophagia	976|Bacteroidetes	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WZS2_k127_8097895_0	404589.Anae109_3108	2.379e-186	593.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	ompB	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,fn3
WZS2_k127_8097895_6	266834.SM_b21463	3.115e-11	64.0	COG1486@1|root,COG1486@2|Bacteria,1NI6G@1224|Proteobacteria,2TTH4@28211|Alphaproteobacteria,4B7GD@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WZS2_k127_8097895_1	717605.Theco_0926	8.524e-153	507.0	COG5520@1|root,COG5520@2|Bacteria,1URVQ@1239|Firmicutes,4HE4Z@91061|Bacilli,26RD8@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	CBM_6,Glyco_hydro_30,Glyco_hydro_30C
WZS2_k127_8097895_3	867845.KI911784_gene1662	2.678e-127	419.0	COG1940@1|root,COG1940@2|Bacteria,2G7R1@200795|Chloroflexi,375G6@32061|Chloroflexia	32061|Chloroflexia	K	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
WZS2_k127_8097895_2	357808.RoseRS_3074	1.419e-136	444.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi,377XY@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS2_k127_8097895_5	1386089.N865_10080	6.163e-28	124.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4FETQ@85021|Intrasporangiaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WZS2_k127_8097895_4	335541.Swol_2185	1.788e-81	276.0	COG1040@1|root,COG1040@2|Bacteria,1UJJJ@1239|Firmicutes,25F4N@186801|Clostridia	186801|Clostridia	S	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8139731_0	926569.ANT_14270	8.481e-174	548.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
WZS2_k127_8139731_1	1122176.KB903538_gene1508	4.648e-96	329.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1IPXC@117747|Sphingobacteriia	976|Bacteroidetes	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
WZS2_k127_8139731_3	349161.Dred_2295	0.0001203	51.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,24AAU@186801|Clostridia	186801|Clostridia	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WZS2_k127_817284_1	1440774.Y900_018470	4.038e-34	141.0	COG0682@1|root,COG0682@2|Bacteria,2GP8C@201174|Actinobacteria,235FI@1762|Mycobacteriaceae	201174|Actinobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
WZS2_k127_817284_0	485913.Krac_10219	2.85e-158	514.0	COG1964@1|root,COG1964@2|Bacteria	2|Bacteria	Q	Radical SAM superfamily	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
WZS2_k127_8192251_5	926569.ANT_15890	3.491e-66	235.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,Methyltransf_11
WZS2_k127_8192251_3	926569.ANT_15880	1.82e-78	270.0	COG0500@1|root,COG2226@2|Bacteria,2G8SE@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS2_k127_8192251_6	925409.KI911562_gene2260	5.857e-12	75.0	COG2227@1|root,COG2227@2|Bacteria,4NGVF@976|Bacteroidetes,1ISIV@117747|Sphingobacteriia	976|Bacteroidetes	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WZS2_k127_8192251_2	926569.ANT_15870	5.998e-149	498.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
WZS2_k127_8192251_0	926569.ANT_15860	0.0	1456.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
WZS2_k127_8192251_1	926569.ANT_27260	2.489e-222	717.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
WZS2_k127_8192251_7	926569.ANT_15850	1.335e-09	71.0	COG4745@1|root,COG4745@2|Bacteria,2G9RB@200795|Chloroflexi	200795|Chloroflexi	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8192251_4	926569.ANT_10810	6.945e-72	250.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WZS2_k127_8192251_8	1121939.L861_21515	7.835e-06	51.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1XIGR@135619|Oceanospirillales	135619|Oceanospirillales	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
WZS2_k127_8193489_4	857293.CAAU_2340	1.755e-19	93.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,36E5G@31979|Clostridiaceae	186801|Clostridia	U	Type II IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WZS2_k127_8193489_0	926569.ANT_29620	4.979e-168	535.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WZS2_k127_8193489_1	926569.ANT_19370	4.425e-98	332.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
WZS2_k127_8193489_3	926569.ANT_29560	3.968e-43	173.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	CP_0034	-	-	-	-	-	-	-	-	-	-	-	BON,FHA,FTSW_RODA_SPOVE,Yop-YscD_cpl
WZS2_k127_8236_2	497964.CfE428DRAFT_0786	1.062e-105	346.0	COG0524@1|root,COG0524@2|Bacteria,46TGU@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
WZS2_k127_8236_5	1116472.MGMO_126c00390	1.639e-09	58.0	COG3250@1|root,COG3250@2|Bacteria,1MVBN@1224|Proteobacteria,1RMER@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 2 family	uidA	GO:0003674,GO:0003824,GO:0004553,GO:0004566,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016054,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0019389,GO:0019391,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
WZS2_k127_8236_6	485913.Krac_2179	8.864e-06	48.0	COG1904@1|root,COG1904@2|Bacteria,2G7Q1@200795|Chloroflexi	200795|Chloroflexi	G	Glucuronate isomerase	-	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
WZS2_k127_8236_4	1123308.KB904550_gene409	4.537e-23	104.0	COG1028@1|root,COG1028@2|Bacteria,1TQ3V@1239|Firmicutes,4HBSW@91061|Bacilli	91061|Bacilli	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	kduD	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
WZS2_k127_8236_3	1219084.AP014508_gene984	2.144e-47	177.0	COG1028@1|root,COG1028@2|Bacteria,2GDVT@200918|Thermotogae	200918|Thermotogae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WZS2_k127_8236_0	926569.ANT_01430	1.121e-177	567.0	COG0362@1|root,COG0362@2|Bacteria,2GBID@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WZS2_k127_8236_1	926569.ANT_31250	5.939e-137	444.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WZS2_k127_8243755_4	448385.sce5740	2.715e-29	132.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,43823@68525|delta/epsilon subdivisions,2X3C5@28221|Deltaproteobacteria,2YVD0@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WZS2_k127_8243755_3	675635.Psed_1306	1.096e-33	134.0	2E8I5@1|root,332W5@2|Bacteria,2GRF8@201174|Actinobacteria,4E68Z@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8243755_2	314278.NB231_12536	2.093e-58	211.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,1SYT9@1236|Gammaproteobacteria,1X25R@135613|Chromatiales	135613|Chromatiales	G	PFAM glucosamine galactosamine-6-phosphate isomerase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
WZS2_k127_8243755_0	595460.RRSWK_00040	1.528e-157	510.0	COG0364@1|root,COG0364@2|Bacteria,2IXCV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
WZS2_k127_8243755_5	1267535.KB906767_gene2483	8.783e-29	125.0	COG1028@1|root,COG1028@2|Bacteria,3Y822@57723|Acidobacteria	57723|Acidobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WZS2_k127_8243755_1	1254432.SCE1572_28920	1.309e-96	321.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
WZS2_k127_8266347_2	926550.CLDAP_26560	9.937e-105	355.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
WZS2_k127_8266347_3	383372.Rcas_4355	2.996e-98	333.0	COG1136@1|root,COG1136@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WZS2_k127_8266347_4	926550.CLDAP_26540	3.346e-71	248.0	COG1136@1|root,COG1136@2|Bacteria,2G6FP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS2_k127_8266347_1	292564.Cyagr_0256	1.669e-131	448.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,22SQM@167375|Cyanobium	1117|Cyanobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_9,Response_reg
WZS2_k127_8266347_0	926550.CLDAP_14400	1.531e-207	657.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2G65R@200795|Chloroflexi	200795|Chloroflexi	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,malic
WZS2_k127_8414086_3	926569.ANT_11390	1.07e-25	107.0	COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WZS2_k127_8414086_0	926569.ANT_08530	5.903e-142	458.0	COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi	200795|Chloroflexi	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
WZS2_k127_8414086_1	926569.ANT_29650	7.408e-79	293.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WZS2_k127_8414086_2	1198452.Jab_2c09850	2.464e-59	207.0	COG0346@1|root,COG0346@2|Bacteria,1RH8Z@1224|Proteobacteria	1224|Proteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WZS2_k127_8431032_4	1303518.CCALI_02088	3.231e-60	213.0	COG3822@1|root,COG3822@2|Bacteria	2|Bacteria	S	D-lyxose isomerase	Z012_00995	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	Lyx_isomer
WZS2_k127_8431032_3	697281.Mahau_2035	8.518e-62	220.0	COG0796@1|root,COG0796@2|Bacteria	2|Bacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
WZS2_k127_8431032_2	1128421.JAGA01000003_gene3375	5.803e-101	337.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
WZS2_k127_8431032_0	1131730.BAVI_16832	3.148e-221	719.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,4HBWH@91061|Bacilli,1ZDCV@1386|Bacillus	91061|Bacilli	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
WZS2_k127_8431032_1	211114.JOEF01000025_gene185	3.185e-101	340.0	COG0491@1|root,COG0491@2|Bacteria,2IBAX@201174|Actinobacteria	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS2_k127_8443355_5	926569.ANT_07490	3.593e-78	273.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
WZS2_k127_8443355_2	926569.ANT_07480	2.151e-123	405.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
WZS2_k127_8443355_3	926569.ANT_07470	1.422e-85	289.0	COG1116@1|root,COG1116@2|Bacteria,2G8C7@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
WZS2_k127_8443355_1	926569.ANT_05010	8.6e-137	445.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
WZS2_k127_8443355_0	926569.ANT_12840	5.417e-227	730.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WZS2_k127_8443355_4	326427.Cagg_2155	2.532e-80	278.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi,375V8@32061|Chloroflexia	32061|Chloroflexia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
WZS2_k127_8486059_7	765420.OSCT_1484	0.0002311	48.0	COG2345@1|root,COG2345@2|Bacteria,2G8V0@200795|Chloroflexi,375MI@32061|Chloroflexia	32061|Chloroflexia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_DeoR
WZS2_k127_8486059_6	926569.ANT_16750	1.048e-21	98.0	COG0125@1|root,COG0125@2|Bacteria,2GBP3@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8486059_2	926569.ANT_16730	1.247e-84	286.0	COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi	200795|Chloroflexi	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
WZS2_k127_8486059_3	555088.DealDRAFT_2880	2.335e-71	252.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes	1239|Firmicutes	I	Lipid kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WZS2_k127_8486059_0	926569.ANT_18360	1.656e-138	446.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
WZS2_k127_8486059_1	926569.ANT_18350	2.873e-93	320.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WZS2_k127_8486059_5	926569.ANT_22190	8.568e-27	124.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
WZS2_k127_8486059_4	1122221.JHVI01000014_gene1367	1.778e-41	154.0	COG0665@1|root,COG0665@2|Bacteria,1WI96@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
WZS2_k127_8487253_1	981384.AEYW01000001_gene1562	1.19e-112	373.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
WZS2_k127_8487253_4	880072.Desac_0096	7.118e-18	89.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_8,PAS_9,Response_reg,SBP_bac_3
WZS2_k127_8487253_2	395961.Cyan7425_0749	8.732e-48	198.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS_8,PAS_9,Response_reg,SpoIIE
WZS2_k127_8487253_0	526227.Mesil_0256	4.337e-134	467.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
WZS2_k127_8487253_5	189753.AXAS01000078_gene6585	1.137e-05	58.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,3JUCX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
WZS2_k127_8487253_3	485913.Krac_8232	1.176e-34	152.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8512012_10	1121434.AULY01000002_gene2269	4.942e-15	77.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QGX@68525|delta/epsilon subdivisions,2WJPU@28221|Deltaproteobacteria,2M8JN@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WZS2_k127_8512012_6	1238182.C882_2632	2.617e-47	172.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2U9D3@28211|Alphaproteobacteria,2JTF9@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2237
WZS2_k127_8512012_4	926569.ANT_30890	1.981e-59	214.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
WZS2_k127_8512012_1	321327.CYA_2555	6.765e-254	800.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1GZ1F@1129|Synechococcus	1117|Cyanobacteria	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
WZS2_k127_8512012_2	926569.ANT_27700	1.15e-114	374.0	COG2220@1|root,COG2220@2|Bacteria,2G6KN@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
WZS2_k127_8512012_3	926569.ANT_24710	2.018e-113	368.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
WZS2_k127_8512012_7	926569.ANT_26960	4.412e-43	171.0	2EH75@1|root,33AYZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8512012_5	926569.ANT_19490	1.731e-56	201.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
WZS2_k127_8512012_0	926569.ANT_19480	4.816e-304	946.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
WZS2_k127_8512012_9	926569.ANT_19460	6.156e-36	143.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
WZS2_k127_8512012_8	926550.CLDAP_40040	1.926e-38	150.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
WZS2_k127_8547977_1	926569.ANT_12980	2.096e-271	865.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
WZS2_k127_8547977_0	324602.Caur_0869	1.174e-307	959.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi,375FT@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WZS2_k127_8547977_2	439235.Dalk_3862	3.843e-106	358.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2WJB1@28221|Deltaproteobacteria,2MM2E@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WZS2_k127_8547977_4	267747.PPA0149	1.884e-45	179.0	COG0438@1|root,COG0438@2|Bacteria,2GNUU@201174|Actinobacteria,4DTBU@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
WZS2_k127_8547977_3	439235.Dalk_2960	2.192e-60	223.0	COG0438@1|root,COG0438@2|Bacteria,1R4V8@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glycos_transf_1
WZS2_k127_8547977_5	880073.Calab_2309	1.301e-20	96.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WZS2_k127_8609270_4	926561.KB900617_gene1221	2.151e-42	166.0	COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,24ET7@186801|Clostridia	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	ahpF	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Thioredoxin_3
WZS2_k127_8609270_6	1236902.ANAS01000042_gene2248	1.998e-19	102.0	COG0685@1|root,COG0685@2|Bacteria	2|Bacteria	E	methylenetetrahydrofolate reductase (NAD(P)H) activity	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
WZS2_k127_8609270_1	1121468.AUBR01000040_gene1732	1.192e-74	270.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,42FH6@68295|Thermoanaerobacterales	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
WZS2_k127_8609270_9	1089553.Tph_c15480	1.28e-06	54.0	COG1150@1|root,COG1150@2|Bacteria,1V8UM@1239|Firmicutes,24J4U@186801|Clostridia,42GMS@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_9
WZS2_k127_8609270_0	322710.Avin_04470	1.769e-79	274.0	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,1SGMS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	CobQ/CobB/MinD/ParA nucleotide binding domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
WZS2_k127_8609270_2	555779.Dthio_PD3240	2.22e-68	241.0	COG3640@1|root,COG3640@2|Bacteria,1R819@1224|Proteobacteria,42PQR@68525|delta/epsilon subdivisions,2WKE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid ac-diamide synthase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
WZS2_k127_8609270_5	926569.ANT_18570	3.323e-24	111.0	COG0400@1|root,COG0400@2|Bacteria,2G7EK@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
WZS2_k127_8609270_3	926569.ANT_20750	2.61e-59	212.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS2_k127_8635401_0	1380394.JADL01000023_gene54	2.063e-85	293.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,2TSZ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WZS2_k127_8635401_1	1480694.DC28_13025	2.75e-73	254.0	COG0329@1|root,COG0329@2|Bacteria,2J5J6@203691|Spirochaetes	203691|Spirochaetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
WZS2_k127_8660805_3	926550.CLDAP_36120	3.717e-92	305.0	COG0318@1|root,COG0318@2|Bacteria,2G7N1@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
WZS2_k127_8660805_2	926550.CLDAP_36080	1.631e-103	351.0	COG3266@1|root,COG3266@2|Bacteria,2G8B4@200795|Chloroflexi	200795|Chloroflexi	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
WZS2_k127_8660805_0	383372.Rcas_0452	1.408e-153	508.0	2BWCS@1|root,32QZE@2|Bacteria,2G818@200795|Chloroflexi,3763T@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8660805_1	357808.RoseRS_4224	6.858e-118	389.0	COG0421@1|root,COG0421@2|Bacteria,2G80S@200795|Chloroflexi,37634@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8694700_11	926569.ANT_08670	6.424e-50	184.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi	200795|Chloroflexi	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
WZS2_k127_8694700_17	926569.ANT_08660	2.548e-30	128.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WZS2_k127_8694700_10	926569.ANT_13840	1.699e-50	190.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_8694700_18	926569.ANT_07860	2.006e-26	122.0	COG1316@1|root,COG1316@2|Bacteria	2|Bacteria	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WZS2_k127_8694700_13	913865.DOT_3759	2.223e-45	179.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,261IW@186807|Peptococcaceae	186801|Clostridia	M	sugar transferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
WZS2_k127_8694700_14	525904.Tter_1178	3.789e-38	160.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8694700_15	525904.Tter_1733	1.133e-36	148.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
WZS2_k127_8694700_16	1454007.JAUG01000006_gene448	2.895e-36	151.0	COG3547@1|root,COG3547@2|Bacteria,4NKDC@976|Bacteroidetes,1ITMK@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
WZS2_k127_8694700_4	926569.ANT_11270	1.79e-80	274.0	COG1811@1|root,COG1811@2|Bacteria,2G6S2@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
WZS2_k127_8694700_6	926569.ANT_11280	7.528e-65	227.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
WZS2_k127_8694700_19	926569.ANT_31290	2.447e-26	125.0	COG0739@1|root,COG3103@1|root,COG0739@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.2.1.96	ko:K01227,ko:K03642	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glucosaminidase,NLPC_P60,Peptidase_M23,SH3_3,SLH
WZS2_k127_8694700_8	1173027.Mic7113_1369	1.206e-56	214.0	COG0457@1|root,COG0457@2|Bacteria,1G8AT@1117|Cyanobacteria,1HCX3@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
WZS2_k127_8694700_0	118168.MC7420_8279	1.694e-237	757.0	COG0457@1|root,COG0457@2|Bacteria,1G8AT@1117|Cyanobacteria,1HCX3@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
WZS2_k127_8694700_20	1203566.HMPREF1285_01048	8.847e-09	63.0	COG1226@1|root,COG1226@2|Bacteria,2GNPM@201174|Actinobacteria	201174|Actinobacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	-	-	-	-	-	-	-	-	-	-	-	-	RyR
WZS2_k127_8694700_2	926550.CLDAP_10700	1.347e-141	456.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
WZS2_k127_8694700_1	926550.CLDAP_10690	4.664e-147	478.0	COG3552@1|root,COG4372@1|root,COG3552@2|Bacteria,COG4372@2|Bacteria,2G60I@200795|Chloroflexi	200795|Chloroflexi	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
WZS2_k127_8694700_5	926569.ANT_30510	1.19e-71	251.0	COG3118@1|root,COG3118@2|Bacteria,2G90Y@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Thioredoxin domain	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
WZS2_k127_8694700_9	926569.ANT_30300	5.027e-51	184.0	2FH2K@1|root,348XD@2|Bacteria,2G93E@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8694700_12	717606.PaecuDRAFT_0704	1.045e-48	181.0	COG4894@1|root,COG4894@2|Bacteria,1VUCV@1239|Firmicutes,4I6QC@91061|Bacilli,26U9X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8694700_3	926569.ANT_30120	2.428e-84	293.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
WZS2_k127_8694700_7	926569.ANT_30110	6.861e-61	219.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
WZS2_k127_8696762_8	1288826.MSNKSG1_13832	3.441e-07	56.0	COG2963@1|root,COG2963@2|Bacteria,1N28U@1224|Proteobacteria,1S9BK@1236|Gammaproteobacteria,46B8H@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
WZS2_k127_8696762_3	485913.Krac_5551	1.997e-77	273.0	COG2801@1|root,COG2801@2|Bacteria,2G8GQ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
WZS2_k127_8696762_2	526227.Mesil_3521	7.161e-82	283.0	28I7A@1|root,2Z8A6@2|Bacteria,1WM6T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8696762_7	926560.KE387027_gene603	2.23e-36	144.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.85,5.4.2.11,5.4.2.12	ko:K01834,ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WZS2_k127_8696762_6	1123401.JHYQ01000001_gene1788	1.302e-49	189.0	COG1266@1|root,COG1266@2|Bacteria,1QSFU@1224|Proteobacteria	1224|Proteobacteria	S	CAAX amino Terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WZS2_k127_8696762_1	926550.CLDAP_14520	5.977e-94	317.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95,1.17.1.9	ko:K00058,ko:K00122	ko00260,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00519,R01513	RC00031,RC02796	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS2_k127_8696762_9	330214.NIDE0678	2.657e-06	52.0	COG2217@1|root,COG2217@2|Bacteria,3J0CY@40117|Nitrospirae	40117|Nitrospirae	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS2_k127_8696762_5	671143.DAMO_0654	7.339e-52	188.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
WZS2_k127_8696762_0	671143.DAMO_0652	1.636e-219	688.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS2_k127_8696762_4	309801.trd_1313	3.139e-62	230.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WZS2_k127_8732921_7	926569.ANT_19070	3.794e-20	93.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WZS2_k127_8732921_4	926569.ANT_19060	1.457e-67	236.0	COG2518@1|root,COG2518@2|Bacteria,2G6NG@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
WZS2_k127_8732921_0	1521187.JPIM01000021_gene167	3.694e-117	385.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
WZS2_k127_8732921_1	661478.OP10G_1818	6.33e-107	357.0	COG1363@1|root,COG1363@2|Bacteria	2|Bacteria	G	aminopeptidase activity	yhfE	-	3.2.1.4	ko:K01179,ko:K01269	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
WZS2_k127_8732921_6	926569.ANT_07030	4.531e-39	150.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
WZS2_k127_8732921_3	316274.Haur_0049	1.669e-76	263.0	COG0664@1|root,COG0664@2|Bacteria,2GAUQ@200795|Chloroflexi,377NH@32061|Chloroflexia	32061|Chloroflexia	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WZS2_k127_8732921_2	926569.ANT_03890	2.182e-79	278.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03890|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8732921_5	926569.ANT_03880	1.124e-47	176.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
WZS2_k127_8796345_0	926569.ANT_11600	1.377e-149	477.0	COG0191@1|root,COG0191@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase activity	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_4960	F_bP_aldolase
WZS2_k127_8796345_1	926569.ANT_11610	1.262e-37	147.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.53,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K13669,ko:K19710	ko00230,map00230	-	R00126,R01054,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT87	-	GT87,NUDIX
WZS2_k127_8796345_5	1449044.JMLE01000012_gene3049	2.525e-19	97.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8796345_4	768671.ThimaDRAFT_1522	2.73e-23	106.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8796345_2	926569.ANT_22250	1.785e-31	138.0	28XMW@1|root,2ZJIW@2|Bacteria,2G9GS@200795|Chloroflexi	926569.ANT_22250|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8796345_3	1123376.AUIU01000016_gene231	9.026e-28	131.0	COG5002@1|root,COG5002@2|Bacteria,3J10G@40117|Nitrospirae	40117|Nitrospirae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS2_k127_8825430_1	926569.ANT_01410	7.319e-104	338.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS2_k127_8825430_2	926569.ANT_01420	9.354e-33	142.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_01420|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8825430_0	926569.ANT_08650	2.179e-182	580.0	COG1207@1|root,COG1207@2|Bacteria,2G5VC@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
WZS2_k127_8854722_2	316274.Haur_1671	1.353e-104	346.0	COG0204@1|root,COG0204@2|Bacteria,2GACB@200795|Chloroflexi,37578@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WZS2_k127_8854722_1	1521187.JPIM01000055_gene3643	1.991e-111	374.0	COG1752@1|root,COG1752@2|Bacteria,2G7GM@200795|Chloroflexi,374ZF@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Patatin	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WZS2_k127_8854722_7	926550.CLDAP_05350	3.099e-22	102.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WZS2_k127_8854722_5	1480694.DC28_07915	3.346e-45	175.0	COG1752@1|root,COG1752@2|Bacteria,2J6JW@203691|Spirochaetes	203691|Spirochaetes	M	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,Patatin
WZS2_k127_8854722_6	479434.Sthe_0747	2.046e-28	118.0	COG1917@1|root,COG1917@2|Bacteria,2G9S4@200795|Chloroflexi,27ZAD@189775|Thermomicrobia	189775|Thermomicrobia	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WZS2_k127_8854722_9	1123320.KB889669_gene3165	1.764e-11	72.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
WZS2_k127_8854722_0	926569.ANT_27870	8.486e-140	448.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WZS2_k127_8854722_4	1128421.JAGA01000002_gene1800	1.538e-47	174.0	COG2166@1|root,COG2166@2|Bacteria	2|Bacteria	S	iron-sulfur cluster assembly	sufE	-	-	ko:K02426,ko:K07125	-	-	-	-	ko00000	-	-	-	SufE
WZS2_k127_8854722_3	368407.Memar_1051	5.984e-51	196.0	COG3187@1|root,arCOG03952@2157|Archaea,2Y55P@28890|Euryarchaeota,2NBFA@224756|Methanomicrobia	224756|Methanomicrobia	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
WZS2_k127_8854722_8	1173023.KE650771_gene4035	4.968e-21	106.0	COG2931@1|root,COG3266@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,1G5GU@1117|Cyanobacteria,1JKDH@1189|Stigonemataceae	1117|Cyanobacteria	Q	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_8989023_0	926569.ANT_21930	3.951e-210	669.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.81,3.2.1.97	ko:K01219,ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	Big_2,CBM_6,Cytochrome_C7,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,WxL
WZS2_k127_8989023_3	138119.DSY4128	6.759e-44	179.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,2644X@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
WZS2_k127_8989023_2	1382306.JNIM01000001_gene1045	6.212e-62	219.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_8989023_5	234267.Acid_6209	1.412e-27	117.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
WZS2_k127_8989023_1	330214.NIDE3889	5.905e-69	240.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
WZS2_k127_8989023_4	237368.SCABRO_01591	8.624e-29	121.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2IX9E@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome b subunit of the bc complex	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B
WZS2_k127_8990390_9	887327.HMPREF0476_2005	6.606e-09	68.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KQ3Y@206351|Neisseriales	206351|Neisseriales	C	Cytochrome c oxidase, subunit	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N,OmpA
WZS2_k127_8990390_7	1123368.AUIS01000005_gene479	1.427e-16	93.0	COG2010@1|root,COG3439@1|root,COG2010@2|Bacteria,COG3439@2|Bacteria,1R6Z0@1224|Proteobacteria,1SFEK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF302
WZS2_k127_8990390_4	370438.PTH_1348	1.503e-51	195.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,26199@186807|Peptococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WZS2_k127_8990390_2	926569.ANT_17490	9.821e-136	438.0	COG1897@1|root,COG1897@2|Bacteria	2|Bacteria	E	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine	metAA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
WZS2_k127_8990390_0	926569.ANT_17480	3.202e-228	711.0	COG2873@1|root,COG2873@2|Bacteria,2G5NS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	CoA_binding_2,Cys_Met_Meta_PP
WZS2_k127_8990390_3	641526.ADIWIN_3096	1.072e-130	428.0	COG0075@1|root,COG0075@2|Bacteria,4NH61@976|Bacteroidetes,1HY2N@117743|Flavobacteriia	976|Bacteroidetes	E	Aminotransferase class-V	phnW	-	2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830,ko:K03430	ko00250,ko00260,ko00440,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00440,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588,R04152	RC00006,RC00008,RC00018,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WZS2_k127_8990390_1	926554.KI912648_gene4944	6.378e-160	523.0	COG1164@1|root,COG1164@2|Bacteria,1WIRX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Oligoendopeptidase, pepF M3 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
WZS2_k127_8990390_8	1521187.JPIM01000046_gene1465	6.04e-11	73.0	294HY@1|root,2ZRXK@2|Bacteria,2GAIJ@200795|Chloroflexi,376D9@32061|Chloroflexia	32061|Chloroflexia	S	YwiC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YwiC
WZS2_k127_8990390_6	926569.ANT_20810	6.229e-27	114.0	COG4818@1|root,COG4818@2|Bacteria,2G9PA@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
WZS2_k127_8990390_5	926569.ANT_09490	5.802e-37	143.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
WZS2_k127_9064797_1	1304874.JAFY01000002_gene575	5.094e-105	353.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	lysDH	-	1.4.1.18	ko:K19064	ko00960,ko01100,ko01110,map00960,map01100,map01110	-	R00446,R02317	RC00062,RC00694	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
WZS2_k127_9064797_6	82654.Pse7367_1552	3.076e-29	123.0	2E363@1|root,32Y5Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9064797_5	1196322.A370_03935	3.712e-50	183.0	COG2128@1|root,COG2128@2|Bacteria,1V55P@1239|Firmicutes,24HT6@186801|Clostridia,36RNR@31979|Clostridiaceae	186801|Clostridia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WZS2_k127_9064797_9	632292.Calhy_1046	5.602e-08	57.0	2BBIP@1|root,32529@2|Bacteria,1UR6J@1239|Firmicutes,24W1J@186801|Clostridia	186801|Clostridia	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
WZS2_k127_9064797_3	255470.cbdbA1715	4.479e-73	256.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi,34CZ8@301297|Dehalococcoidia	301297|Dehalococcoidia	V	Domain of unknown function (DUF4162)	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WZS2_k127_9064797_7	1254432.SCE1572_36870	9.914e-22	110.0	COG4377@1|root,COG4377@2|Bacteria,1QACG@1224|Proteobacteria,43DZN@68525|delta/epsilon subdivisions,2WZAB@28221|Deltaproteobacteria,2Z1PM@29|Myxococcales	28221|Deltaproteobacteria	S	Putative membrane peptidase family (DUF2324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
WZS2_k127_9064797_8	562743.JH976444_gene585	4.366e-11	76.0	COG1668@1|root,COG1668@2|Bacteria,1UIRA@1239|Firmicutes,4ISR6@91061|Bacilli	91061|Bacilli	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
WZS2_k127_9064797_0	1173028.ANKO01000042_gene858	7.293e-281	887.0	COG2366@1|root,COG2366@2|Bacteria,1G4M5@1117|Cyanobacteria	1117|Cyanobacteria	S	penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
WZS2_k127_9064797_2	485913.Krac_2215	2.284e-102	350.0	COG4552@1|root,COG4552@2|Bacteria,2G7MV@200795|Chloroflexi	200795|Chloroflexi	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WZS2_k127_9064797_4	251221.35211789	1.968e-64	224.0	COG0115@1|root,COG0115@2|Bacteria,1G1GM@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WZS2_k127_906881_9	867845.KI911784_gene692	2.416e-20	93.0	COG2197@1|root,COG2197@2|Bacteria,2G7VT@200795|Chloroflexi,376CA@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_906881_3	867845.KI911784_gene695	1.737e-164	544.0	COG4213@1|root,COG4213@2|Bacteria,2G6C4@200795|Chloroflexi,377C5@32061|Chloroflexia	32061|Chloroflexia	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
WZS2_k127_906881_1	926569.ANT_01780	2.395e-217	698.0	COG1653@1|root,COG1653@2|Bacteria,2G5UT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117,ko:K17315	ko02010,map02010	M00196,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.28,3.A.1.1.30	-	-	SBP_bac_1,SBP_bac_8
WZS2_k127_906881_4	926569.ANT_01790	6.892e-142	456.0	COG1175@1|root,COG1175@2|Bacteria,2G5W9@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
WZS2_k127_906881_5	926569.ANT_01800	6.246e-137	442.0	COG0395@1|root,COG0395@2|Bacteria,2G5SY@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
WZS2_k127_906881_0	326427.Cagg_2577	9.602e-249	775.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi,376BP@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
WZS2_k127_906881_2	867845.KI911784_gene693	2.808e-178	567.0	COG4214@1|root,COG4214@2|Bacteria,2G8H9@200795|Chloroflexi,376ZS@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
WZS2_k127_906881_8	1341181.FLJC2902T_14620	1.162e-23	113.0	COG5635@1|root,COG5635@2|Bacteria,4NHE7@976|Bacteroidetes,1ICWF@117743|Flavobacteriia,2NY86@237|Flavobacterium	976|Bacteroidetes	T	Domain of unknown function (DUF4062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062
WZS2_k127_906881_7	67257.JODR01000032_gene2700	1.162e-23	113.0	COG1396@1|root,COG1396@2|Bacteria,2GKX8@201174|Actinobacteria	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_906881_6	994479.GL877878_gene1908	2.927e-101	343.0	COG0624@1|root,COG0624@2|Bacteria,2I9HB@201174|Actinobacteria	201174|Actinobacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
WZS2_k127_9168989_5	292563.Cyast_2134	1.431e-06	57.0	COG0642@1|root,COG2205@2|Bacteria,1G3D2@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c
WZS2_k127_9168989_0	1128421.JAGA01000002_gene1976	1.583e-154	493.0	COG3458@1|root,COG3458@2|Bacteria,2NQIP@2323|unclassified Bacteria	2|Bacteria	Q	Acetyl xylan esterase (AXE1)	cah3	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005975,GO:0005976,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009308,GO:0009987,GO:0010383,GO:0010410,GO:0016787,GO:0016788,GO:0016999,GO:0017144,GO:0019213,GO:0019752,GO:0030653,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043645,GO:0044036,GO:0044106,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0045491,GO:0046483,GO:0046555,GO:0046872,GO:0047739,GO:0052689,GO:0071554,GO:0071704,GO:0072338,GO:1901266,GO:1901360,GO:1901564	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
WZS2_k127_9168989_1	1035308.AQYY01000001_gene2006	4.812e-52	191.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,264ZM@186807|Peptococcaceae	186801|Clostridia	S	conserved protein (DUF2174)	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
WZS2_k127_9168989_4	42256.RradSPS_2809	1.947e-10	72.0	2E64T@1|root,330TJ@2|Bacteria,2H60Q@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9168989_2	324602.Caur_0327	8.015e-24	106.0	COG1917@1|root,COG1917@2|Bacteria,2G7C7@200795|Chloroflexi,377HW@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9168989_3	358396.C445_04253	2.443e-18	87.0	COG2301@1|root,arCOG00760@2157|Archaea,2XUK3@28890|Euryarchaeota,23S1V@183963|Halobacteria	183963|Halobacteria	G	COG2301 Citrate lyase beta subunit	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
WZS2_k127_9234672_0	518766.Rmar_1549	2.766e-174	559.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FIUV@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	dehydrogenase, E1 component	bfmBAB	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
WZS2_k127_9234672_2	926550.CLDAP_34120	5.918e-52	200.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WZS2_k127_9234672_3	1521187.JPIM01000101_gene3500	5.36e-49	200.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,37570@32061|Chloroflexia	32061|Chloroflexia	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
WZS2_k127_9234672_5	1226322.HMPREF1545_01464	5.547e-29	123.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,2N798@216572|Oscillospiraceae	186801|Clostridia	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WZS2_k127_9234672_1	926550.CLDAP_37050	1.391e-114	377.0	COG0667@1|root,COG0667@2|Bacteria,2G631@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS2_k127_9234672_4	485913.Krac_7163	2.829e-34	144.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WZS2_k127_9316724_0	1265313.HRUBRA_02490	6.618e-195	612.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1J57N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WZS2_k127_9316724_3	247634.GPB2148_1087	1.203e-57	205.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WZS2_k127_9316724_4	1122599.AUGR01000024_gene1353	3.239e-37	151.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1S1MF@1236|Gammaproteobacteria,1XJ0P@135619|Oceanospirillales	135619|Oceanospirillales	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
WZS2_k127_9316724_2	1121374.KB891587_gene3083	2.584e-74	253.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
WZS2_k127_9316724_1	45351.EDO26892	9.675e-172	542.0	COG0304@1|root,KOG1394@2759|Eukaryota,3AGBW@33154|Opisthokonta,3BYGE@33208|Metazoa	33208|Metazoa	G	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ketoacyl-synt
WZS2_k127_9319098_2	395494.Galf_2689	2.416e-69	239.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,44UYU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WZS2_k127_9319098_1	313606.M23134_05528	7.32e-103	350.0	2DB74@1|root,2Z7JN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9319098_0	926569.ANT_23260	5.708e-147	485.0	COG1032@1|root,COG1032@2|Bacteria,2G86N@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS2_k127_9377286_2	926569.ANT_12010	6.696e-104	343.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WZS2_k127_9377286_1	926569.ANT_12000	3.927e-136	446.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WZS2_k127_9377286_0	926569.ANT_11990	6.474e-171	548.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
WZS2_k127_9415155_1	383372.Rcas_1202	7.411e-123	397.0	COG2013@1|root,COG2013@2|Bacteria,2G7F5@200795|Chloroflexi,3753I@32061|Chloroflexia	32061|Chloroflexia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,zinc_ribbon_2
WZS2_k127_9415155_0	485913.Krac_2238	7.317e-156	526.0	COG0642@1|root,COG4191@1|root,COG2205@2|Bacteria,COG4191@2|Bacteria,2G7JR@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
WZS2_k127_9415155_2	1195236.CTER_3214	8.034e-120	397.0	COG2334@1|root,COG2334@2|Bacteria,1VRV5@1239|Firmicutes,25EGP@186801|Clostridia,3WHGG@541000|Ruminococcaceae	186801|Clostridia	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
WZS2_k127_9415155_5	1499967.BAYZ01000095_gene4190	1.823e-54	198.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CBM9_2,HATPase_c,HisKA,Response_reg
WZS2_k127_9415155_4	944481.JAFP01000001_gene423	3.105e-98	327.0	COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,42R4B@68525|delta/epsilon subdivisions,2WMZN@28221|Deltaproteobacteria,2M734@213113|Desulfurellales	28221|Deltaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS2_k127_9415155_3	1210884.HG799463_gene10153	2.585e-98	327.0	COG1788@1|root,COG1788@2|Bacteria	2|Bacteria	I	CoA-transferase activity	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS2_k127_9441458_3	926569.ANT_02650	3.358e-113	370.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi	2|Bacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS2_k127_9441458_2	926569.ANT_02640	1.713e-117	390.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS2_k127_9441458_1	926569.ANT_02630	3.025e-118	388.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WZS2_k127_9441458_4	717231.Flexsi_1795	1.75e-100	335.0	COG1117@1|root,COG1117@2|Bacteria,2GF94@200930|Deferribacteres	200930|Deferribacteres	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WZS2_k127_9441458_7	237368.SCABRO_01122	8.692e-49	183.0	COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes	203682|Planctomycetes	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WZS2_k127_9441458_9	324602.Caur_1822	1.168e-20	93.0	COG0695@1|root,COG0695@2|Bacteria,2G75B@200795|Chloroflexi	200795|Chloroflexi	O	Glutathione S-transferase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
WZS2_k127_9441458_5	765420.OSCT_1040	4.839e-98	329.0	COG1612@1|root,COG1612@2|Bacteria,2G75U@200795|Chloroflexi,376ZK@32061|Chloroflexia	32061|Chloroflexia	O	PFAM cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
WZS2_k127_9441458_8	1267535.KB906767_gene980	1.148e-36	141.0	COG1359@1|root,COG1359@2|Bacteria,3Y8I5@57723|Acidobacteria	57723|Acidobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
WZS2_k127_9441458_0	765420.OSCT_1980	9.377e-160	526.0	COG5316@1|root,COG5316@2|Bacteria,2GBUR@200795|Chloroflexi,375C5@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9441458_6	926550.CLDAP_06530	1.834e-54	193.0	COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
WZS2_k127_9469898_6	383372.Rcas_4217	1.34e-59	210.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi,3769A@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
WZS2_k127_9469898_4	357808.RoseRS_0026	1.237e-129	429.0	COG1169@1|root,COG1169@2|Bacteria,2G5RQ@200795|Chloroflexi,375P4@32061|Chloroflexia	32061|Chloroflexia	HQ	TIGRFAM isochorismate synthase	-	-	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
WZS2_k127_9469898_7	357808.RoseRS_0027	3.686e-57	205.0	COG1309@1|root,COG1309@2|Bacteria,2G7DR@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WZS2_k127_9469898_1	525904.Tter_1381	1.035e-258	822.0	COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria	2|Bacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WZS2_k127_9469898_3	926569.ANT_20720	6.826e-169	538.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
WZS2_k127_9469898_5	44689.DDB0231354	9.606e-115	374.0	COG0588@1|root,KOG0235@2759|Eukaryota,3X9BI@554915|Amoebozoa	554915|Amoebozoa	G	Phosphoglycerate mutase	-	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
WZS2_k127_9469898_9	926569.ANT_20710	6.336e-40	157.0	COG4478@1|root,COG4478@2|Bacteria,2G9EA@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
WZS2_k127_9469898_2	926569.ANT_20700	3.767e-172	554.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
WZS2_k127_9469898_10	765420.OSCT_2130	4.329e-21	96.0	COG2127@1|root,COG2127@2|Bacteria,2G9F8@200795|Chloroflexi,375WT@32061|Chloroflexia	32061|Chloroflexia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
WZS2_k127_9469898_8	926569.ANT_06060	5.039e-52	187.0	COG1970@1|root,COG1970@2|Bacteria,2G733@200795|Chloroflexi	200795|Chloroflexi	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WZS2_k127_9469898_0	926569.ANT_16840	0.0	1274.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WZS2_k127_9484076_0	926569.ANT_03940	1.425e-156	496.0	COG0538@1|root,COG0538@2|Bacteria,2G5SM@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
WZS2_k127_9484076_1	926569.ANT_25670	2.909e-133	443.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
WZS2_k127_9484076_2	926569.ANT_25680	4.521e-89	302.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WZS2_k127_9505068_1	926569.ANT_12650	1.438e-138	447.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WZS2_k127_9505068_2	639282.DEFDS_1384	4.481e-82	288.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
WZS2_k127_9505068_0	926569.ANT_21940	1.006e-179	578.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
WZS2_k127_9505068_6	1125863.JAFN01000001_gene1841	1.241e-10	73.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
WZS2_k127_9505068_5	523841.HFX_2210	2.804e-53	198.0	COG0437@1|root,arCOG01500@2157|Archaea,2XU83@28890|Euryarchaeota,23TXG@183963|Halobacteria	183963|Halobacteria	C	COG0437 Fe-S-cluster-containing hydrogenase components 1	hmoA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4,Fer4_11
WZS2_k127_9505068_4	1304872.JAGC01000009_gene663	1.323e-70	254.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42N47@68525|delta/epsilon subdivisions,2WIKZ@28221|Deltaproteobacteria,2M8JX@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	qrcD	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
WZS2_k127_9505068_3	290397.Adeh_2002	2.745e-77	272.0	COG3005@1|root,COG3005@2|Bacteria,1QYG3@1224|Proteobacteria,43CC8@68525|delta/epsilon subdivisions,2X7N4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
WZS2_k127_9524365_6	883110.HMPREF9260_00908	2.917e-18	86.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli,27E41@186827|Aerococcaceae	91061|Bacilli	L	SLBB domain	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
WZS2_k127_9524365_4	926569.ANT_11190	1.098e-108	353.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
WZS2_k127_9524365_0	926569.ANT_11210	1.418e-205	651.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
WZS2_k127_9524365_3	926569.ANT_12110	1.066e-137	456.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	2.7.7.6	ko:K03046,ko:K03641,ko:K08642	ko00230,ko00240,ko01100,ko02024,ko03020,map00230,map00240,map01100,map02024,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021,ko03400	2.C.1.2	-	-	Glyco_hydro_18,LysM,OapA,PD40,Peptidase_M23
WZS2_k127_9524365_2	926569.ANT_12100	2.237e-140	465.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
WZS2_k127_9524365_1	926569.ANT_12080	5.517e-185	591.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
WZS2_k127_9524365_5	926569.ANT_16140	2.145e-90	310.0	COG0524@1|root,COG0524@2|Bacteria,2G9QW@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WZS2_k127_9524365_7	326427.Cagg_1901	3.701e-12	69.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS2_k127_9552285_6	926569.ANT_18500	9.8e-09	58.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
WZS2_k127_9552285_4	926569.ANT_18500	6.947e-31	125.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
WZS2_k127_9552285_2	459495.SPLC1_S203210	1.158e-50	190.0	COG1943@1|root,COG1943@2|Bacteria,1G6DG@1117|Cyanobacteria,1HBDG@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WZS2_k127_9552285_0	926569.ANT_07760	1.593e-133	430.0	COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WZS2_k127_9552285_5	667014.Thein_0724	4.824e-18	86.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
WZS2_k127_9552285_3	323259.Mhun_2151	1.147e-36	142.0	COG1848@1|root,arCOG02222@2157|Archaea,2Y1YE@28890|Euryarchaeota	28890|Euryarchaeota	V	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
WZS2_k127_9552285_1	926569.ANT_07770	4.794e-130	419.0	COG0171@1|root,COG0171@2|Bacteria,2G6X3@200795|Chloroflexi	200795|Chloroflexi	H	NAD synthase	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WZS2_k127_9552285_7	661478.OP10G_1998	1.288e-07	54.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
WZS2_k127_9567485_0	1499967.BAYZ01000164_gene6661	1.78e-130	455.0	COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG5002@2|Bacteria,2NS5N@2323|unclassified Bacteria	2|Bacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,PilJ,Response_reg,dCache_1
WZS2_k127_9567485_1	1148.1653077	1.802e-127	419.0	COG3437@1|root,COG3437@2|Bacteria,1G2ZH@1117|Cyanobacteria	1117|Cyanobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD
WZS2_k127_9567485_2	1278307.KB906986_gene4273	4.398e-19	88.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
WZS2_k127_9574508_1	485913.Krac_0278	1.306e-102	344.0	COG0604@1|root,COG0604@2|Bacteria,2G84Q@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WZS2_k127_9574508_8	1463917.JODC01000007_gene7491	7.578e-33	132.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
WZS2_k127_9574508_4	661478.OP10G_4309	1.819e-60	216.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WZS2_k127_9574508_7	485913.Krac_0885	2.011e-35	144.0	COG4978@1|root,COG4978@2|Bacteria	2|Bacteria	-	-	MA20_43725	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,Polyketide_cyc2
WZS2_k127_9574508_13	717606.PaecuDRAFT_3449	1.869e-16	81.0	COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli,26QCU@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
WZS2_k127_9574508_12	767434.Fraau_0207	1.18e-23	105.0	2DPD4@1|root,331JQ@2|Bacteria,1N9S4@1224|Proteobacteria,1SCY8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3224)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3224
WZS2_k127_9574508_5	1120934.KB894444_gene2480	1.95e-40	155.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria,4E5HN@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
WZS2_k127_9574508_2	875328.JDM601_1645	4.274e-68	236.0	COG2020@1|root,COG2020@2|Bacteria,2IIDW@201174|Actinobacteria	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WZS2_k127_9574508_9	246197.MXAN_1686	1.34e-31	136.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,FR47
WZS2_k127_9574508_3	867845.KI911784_gene2163	6.477e-68	238.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,376HK@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_9574508_10	926554.KI912671_gene390	1.822e-29	131.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1WM3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_4,PAS_8
WZS2_k127_9574508_14	1444309.JAQG01000087_gene2638	2.006e-09	68.0	COG2770@1|root,COG4585@1|root,COG2770@2|Bacteria,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli,26TTZ@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	vraS	-	2.7.13.3	ko:K07681,ko:K11617	ko02020,map02020	M00480,M00481,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
WZS2_k127_9574508_11	479434.Sthe_0243	2.829e-24	108.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS2_k127_9574508_0	1121324.CLIT_10c01870	2.8e-135	447.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS2_k127_9574508_15	211114.JOEF01000019_gene528	2.199e-06	53.0	COG2234@1|root,COG2234@2|Bacteria,2I9BM@201174|Actinobacteria,4E24E@85010|Pseudonocardiales	201174|Actinobacteria	G	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WZS2_k127_967863_0	926569.ANT_10660	1.114e-191	603.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WZS2_k127_967863_5	867845.KI911784_gene3077	4.171e-56	204.0	COG5522@1|root,COG5522@2|Bacteria	2|Bacteria	S	Integral membrane protein (intg_mem_TP0381)	ywaF	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
WZS2_k127_967863_7	111780.Sta7437_4010	5.772e-24	108.0	COG0454@1|root,COG0456@2|Bacteria,1G7ME@1117|Cyanobacteria,3VK6H@52604|Pleurocapsales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03828	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
WZS2_k127_967863_6	562970.Btus_0118	2.347e-36	145.0	COG1309@1|root,COG1309@2|Bacteria,1V3QD@1239|Firmicutes,4IQ6R@91061|Bacilli,27AQ7@186823|Alicyclobacillaceae	91061|Bacilli	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WZS2_k127_967863_4	316274.Haur_3168	2.083e-71	254.0	COG0491@1|root,COG0491@2|Bacteria,2GAIA@200795|Chloroflexi,376BC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS2_k127_967863_3	357808.RoseRS_2972	1.547e-120	397.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS2_k127_967863_2	357808.RoseRS_2971	8.196e-161	516.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi,3763W@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS2_k127_967863_1	383372.Rcas_1887	1.637e-165	538.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
WZS2_k127_9681300_8	218497.CAB704	0.0001288	50.0	COG4974@1|root,COG4974@2|Bacteria,2JFCQ@204428|Chlamydiae	204428|Chlamydiae	D	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS2_k127_9681300_6	529709.PYCH_00910	6.544e-07	61.0	COG0582@1|root,arCOG01241@2157|Archaea,2XV3E@28890|Euryarchaeota,242ZK@183968|Thermococci	183968|Thermococci	J	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerA	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
WZS2_k127_9681300_2	383372.Rcas_0224	3.781e-33	133.0	COG2010@1|root,COG2010@2|Bacteria,2G6R3@200795|Chloroflexi,377DZ@32061|Chloroflexia	32061|Chloroflexia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
WZS2_k127_9681300_1	382245.ASA_2191	1.237e-33	143.0	COG3760@1|root,COG3760@2|Bacteria,1RDIG@1224|Proteobacteria,1S5WN@1236|Gammaproteobacteria,1Y64S@135624|Aeromonadales	135624|Aeromonadales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
WZS2_k127_9681300_0	1127673.GLIP_2427	3.433e-69	246.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RRQE@1236|Gammaproteobacteria,466I8@72275|Alteromonadaceae	1236|Gammaproteobacteria	EH	COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
WZS2_k127_9681300_5	945550.VISI1226_15761	1.521e-12	71.0	COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,1RP9G@1236|Gammaproteobacteria,1XSF1@135623|Vibrionales	135623|Vibrionales	U	COG4962 Flp pilus assembly protein, ATPase CpaF	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WZS2_k127_9681300_4	292415.Tbd_1700	2.03e-16	82.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
WZS2_k127_9681300_3	926569.ANT_29430	1.312e-21	96.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WZS2_k127_975471_8	994573.T472_0205120	3.667e-21	109.0	COG1361@1|root,COG4932@1|root,COG1361@2|Bacteria,COG4932@2|Bacteria,1VIJZ@1239|Firmicutes	1239|Firmicutes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
WZS2_k127_975471_6	1499967.BAYZ01000005_gene5444	7.422e-67	236.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
WZS2_k127_975471_5	1499967.BAYZ01000005_gene5443	4.208e-85	289.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,SBP_bac_1,SBP_bac_8,UTRA
WZS2_k127_975471_4	1499967.BAYZ01000005_gene5442	3.504e-86	291.0	COG0145@1|root,COG0145@2|Bacteria	2|Bacteria	EQ	ligase activity	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	iNJ661.Rv0266c	DUF1638,Hydant_A_N,Hydantoinase_A,Hydantoinase_B
WZS2_k127_975471_1	1499967.BAYZ01000005_gene5440	3.736e-112	368.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WZS2_k127_975471_3	1499967.BAYZ01000005_gene5439	7.905e-87	291.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
WZS2_k127_975471_2	1121430.JMLG01000030_gene1600	2.942e-89	310.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,26492@186807|Peptococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
WZS2_k127_975471_7	709986.Deima_0214	3.386e-60	226.0	COG0477@1|root,COG2814@2|Bacteria,1WNFE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS2_k127_975471_0	264732.Moth_2112	2.836e-156	512.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
WZS2_k127_9760324_5	926569.ANT_14620	3.972e-14	74.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WZS2_k127_9760324_3	926569.ANT_14610	1.139e-52	189.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WZS2_k127_9760324_6	926569.ANT_15060	8.203e-05	51.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
WZS2_k127_9760324_4	926569.ANT_15050	6.317e-46	176.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
WZS2_k127_9760324_1	926569.ANT_18140	4.739e-153	492.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi	200795|Chloroflexi	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
WZS2_k127_9760324_0	926569.ANT_18150	3.135e-194	616.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WZS2_k127_97627_0	1121468.AUBR01000034_gene1374	2.235e-233	734.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
WZS2_k127_97627_1	926569.ANT_20910	5.574e-102	341.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WZS2_k127_97627_4	926569.ANT_20920	5.012e-24	106.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
WZS2_k127_97627_2	926569.ANT_20930	1.321e-78	277.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi	200795|Chloroflexi	M	glycosyl transferase group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WZS2_k127_97627_5	926569.ANT_04340	1.641e-20	96.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	mec	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
WZS2_k127_9781762_11	405948.SACE_4048	1.851e-07	61.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria,4E4KM@85010|Pseudonocardiales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
WZS2_k127_9781762_1	926569.ANT_00620	1.254e-99	337.0	COG0438@1|root,COG0438@2|Bacteria,2G9D7@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
WZS2_k127_9781762_4	926569.ANT_31610	5.785e-81	286.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	wzx	-	-	ko:K16694	-	-	-	-	ko00000,ko02000	2.A.66.2.6	-	-	Polysacc_synt_3
WZS2_k127_9781762_3	926569.ANT_31640	3.728e-82	277.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WZS2_k127_9781762_8	926569.ANT_31650	4.765e-35	140.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi	200795|Chloroflexi	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
WZS2_k127_9781762_5	926569.ANT_31660	3.334e-69	241.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
WZS2_k127_9781762_6	926569.ANT_31670	4.838e-56	200.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi	200795|Chloroflexi	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WZS2_k127_9781762_0	926569.ANT_25570	2.476e-259	820.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi	200795|Chloroflexi	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WZS2_k127_9781762_2	926569.ANT_02540	1.644e-89	306.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WZS2_k127_9781762_7	926569.ANT_06880	2.183e-44	173.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
WZS2_k127_9781762_10	596152.DesU5LDRAFT_1113	1.903e-21	105.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,1PFBF@1224|Proteobacteria,42RAR@68525|delta/epsilon subdivisions,2WN52@28221|Deltaproteobacteria,2M9X4@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,SpoIIE
WZS2_k127_9802074_0	357808.RoseRS_3083	3.13e-125	413.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS2_k127_9802074_1	1173024.KI912150_gene1249	2.115e-64	229.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1JJWX@1189|Stigonemataceae	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
WZS2_k127_9802074_5	926569.ANT_31060	2.932e-37	149.0	COG1011@1|root,COG1011@2|Bacteria,2G787@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
WZS2_k127_9802074_3	479434.Sthe_0226	4.982e-42	164.0	COG3153@1|root,COG3153@2|Bacteria,2G7B4@200795|Chloroflexi	200795|Chloroflexi	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
WZS2_k127_9802074_8	485913.Krac_1782	2.766e-30	132.0	COG0454@1|root,COG0456@2|Bacteria,2G92V@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_9802074_2	926569.ANT_04400	1.313e-60	222.0	COG0454@1|root,COG1247@1|root,COG0456@2|Bacteria,COG1247@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS2_k127_9802074_6	1087481.AGFX01000011_gene3812	8.729e-36	145.0	COG1670@1|root,COG1670@2|Bacteria,1V8EU@1239|Firmicutes,4HJPX@91061|Bacilli,26VDI@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS2_k127_9802074_4	1461580.CCAS010000087_gene4365	5.115e-38	149.0	COG1670@1|root,COG1670@2|Bacteria,1V3Q8@1239|Firmicutes,4HH72@91061|Bacilli,1ZQWD@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS2_k127_9802074_7	1294265.JCM21738_3766	3.829e-33	135.0	COG1670@1|root,COG1670@2|Bacteria,1V3Q8@1239|Firmicutes,4HH72@91061|Bacilli,1ZQWD@1386|Bacillus	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS2_k127_9802074_9	1168059.KB899087_gene1681	6.548e-25	115.0	COG1135@1|root,COG1135@2|Bacteria,1QTTK@1224|Proteobacteria,2TQSF@28211|Alphaproteobacteria,3EZ0U@335928|Xanthobacteraceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
WZS2_k127_9804613_9	926569.ANT_03850	1.221e-79	281.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi	200795|Chloroflexi	T	SMART helix-turn-helix domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
WZS2_k127_9804613_15	1082933.MEA186_23816	1.428e-20	98.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.1.1.137,2.3.1.1	ko:K00537,ko:K00619,ko:K07755	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
WZS2_k127_9804613_10	1499967.BAYZ01000013_gene6463	3.012e-73	258.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
WZS2_k127_9804613_0	765420.OSCT_2101	4.977e-230	723.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
WZS2_k127_9804613_2	1379698.RBG1_1C00001G1459	7.012e-140	455.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS2_k127_9804613_12	272557.APE_0122.1	9.323e-53	191.0	COG0537@1|root,arCOG00419@2157|Archaea,2XQK8@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
WZS2_k127_9804613_4	926569.ANT_26230	1.224e-129	426.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WZS2_k127_9804613_16	926569.ANT_26240	2.465e-09	63.0	COG1722@1|root,COG1722@2|Bacteria,2G7IN@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WZS2_k127_9804613_14	926569.ANT_26250	5.93e-47	173.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
WZS2_k127_9804613_11	1128421.JAGA01000003_gene3490	4.094e-57	205.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
WZS2_k127_9804613_5	479434.Sthe_1638	2.677e-97	331.0	COG0624@1|root,COG0624@2|Bacteria,2G60R@200795|Chloroflexi,27Y02@189775|Thermomicrobia	189775|Thermomicrobia	E	peptidase dimerisation domain protein	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS2_k127_9804613_8	357808.RoseRS_1604	4.538e-88	299.0	COG3570@1|root,COG3570@2|Bacteria,2G7VJ@200795|Chloroflexi	200795|Chloroflexi	H	PFAM aminoglycoside hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
WZS2_k127_9804613_7	452637.Oter_0662	4.544e-91	309.0	COG4975@1|root,COG4975@2|Bacteria	2|Bacteria	G	carbohydrate transmembrane transporter activity	glcU	GO:0003674,GO:0005215,GO:0005355,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0022857,GO:0034219,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1904659	-	ko:K05340,ko:K06216	-	-	-	-	ko00000,ko02000	2.A.7.5	-	-	Sugar_transport,Ureide_permease
WZS2_k127_9804613_17	386456.JQKN01000004_gene177	0.0004025	52.0	arCOG06670@1|root,arCOG06670@2157|Archaea,2Y58G@28890|Euryarchaeota	28890|Euryarchaeota	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
WZS2_k127_9804613_3	926569.ANT_19820	4.264e-131	431.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WZS2_k127_9804613_1	926569.ANT_29800	1.025e-215	679.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WZS2_k127_9804613_13	383372.Rcas_0827	1.22e-50	188.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	yueE	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	Guanylate_cyc,HD
WZS2_k127_9804613_6	1040986.ATYO01000012_gene5293	3.312e-91	338.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TYI3@28211|Alphaproteobacteria,43RTK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,PAS_9,Response_reg
WZS2_k127_9837992_1	1382306.JNIM01000001_gene368	1.273e-65	233.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene368|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9837992_2	867845.KI911784_gene2148	1.238e-57	225.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WZS2_k127_9837992_3	926550.CLDAP_24510	2.547e-46	190.0	COG2273@1|root,COG2273@2|Bacteria,2G7RY@200795|Chloroflexi	200795|Chloroflexi	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
WZS2_k127_9837992_5	1033743.CAES01000049_gene486	8.685e-07	61.0	COG4447@1|root,COG4447@2|Bacteria,1V10R@1239|Firmicutes,4IPNU@91061|Bacilli,27614@186822|Paenibacillaceae	91061|Bacilli	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR,Sortilin-Vps10
WZS2_k127_9837992_0	926569.ANT_28950	2.391e-214	679.0	COG0659@1|root,COG0659@2|Bacteria,2G7JI@200795|Chloroflexi	200795|Chloroflexi	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WZS2_k127_9837992_4	926569.ANT_20480	4.785e-29	121.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9837992_6	1123376.AUIU01000001_gene793	4.433e-06	51.0	COG4980@1|root,COG4980@2|Bacteria,3J1B3@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
WZS2_k127_9856765_2	671143.DAMO_0407	2.498e-137	444.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WZS2_k127_9856765_3	398767.Glov_3227	4.995e-111	377.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
WZS2_k127_9856765_5	926569.ANT_09260	1.942e-87	294.0	COG0745@1|root,COG0745@2|Bacteria,2G6JP@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS2_k127_9856765_1	926569.ANT_01650	1.232e-163	518.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
WZS2_k127_9856765_8	926569.ANT_01660	4.242e-81	274.0	COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
WZS2_k127_9856765_0	926569.ANT_01680	5.047e-219	692.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
WZS2_k127_9856765_9	926569.ANT_01690	4.794e-76	262.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WZS2_k127_9856765_12	926569.ANT_30190	2.403e-47	173.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
WZS2_k127_9856765_10	926550.CLDAP_06860	1.106e-69	243.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WZS2_k127_9856765_11	644966.Tmar_2131	2.329e-67	238.0	COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,24HM8@186801|Clostridia,3WDT7@538999|Clostridiales incertae sedis	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
WZS2_k127_9856765_6	926569.ANT_29790	8.503e-87	294.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
WZS2_k127_9856765_13	160488.PP_1946	8.817e-41	160.0	COG1028@1|root,COG1028@2|Bacteria,1PEA0@1224|Proteobacteria,1RWPS@1236|Gammaproteobacteria,1YZ1T@136845|Pseudomonas putida group	1236|Gammaproteobacteria	C	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K18335	ko00051,ko01120,map00051,map01120	-	R10690	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WZS2_k127_9856765_4	292459.STH212	2.312e-96	321.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
WZS2_k127_9856765_7	926569.ANT_29760	3.591e-82	280.0	COG2746@1|root,COG2746@2|Bacteria	2|Bacteria	V	aminoglycoside 3-N-acetyltransferase activity	yokD	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
WZS2_k127_9856765_16	926569.ANT_29890	9.847e-30	118.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WZS2_k127_9937054_28	204669.Acid345_2204	5.792e-06	49.0	COG0705@1|root,COG0705@2|Bacteria,3Y5A9@57723|Acidobacteria,2JNBE@204432|Acidobacteriia	204432|Acidobacteriia	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WZS2_k127_9937054_19	1463821.JOGR01000001_gene1376	6.57e-61	218.0	COG2227@1|root,COG2227@2|Bacteria,2I8GJ@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS2_k127_9937054_17	926569.ANT_22270	1.361e-89	304.0	COG0153@1|root,COG1210@1|root,COG0153@2|Bacteria,COG1210@2|Bacteria,2G6XV@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WZS2_k127_9937054_21	926569.ANT_22780	2.086e-38	150.0	COG1047@1|root,COG1047@2|Bacteria,2G744@200795|Chloroflexi	200795|Chloroflexi	G	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
WZS2_k127_9937054_18	1128421.JAGA01000002_gene1676	2.049e-68	244.0	COG0265@1|root,COG0265@2|Bacteria,2NQV1@2323|unclassified Bacteria	2|Bacteria	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WZS2_k127_9937054_23	383372.Rcas_1228	9.136e-35	140.0	COG2197@1|root,COG2197@2|Bacteria,2G73R@200795|Chloroflexi,377PI@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
WZS2_k127_9937054_20	1128421.JAGA01000003_gene3504	7.869e-50	193.0	COG3597@1|root,COG3597@2|Bacteria,2NRGV@2323|unclassified Bacteria	2|Bacteria	S	protein domain associated with	ycgC	-	-	ko:K03595,ko:K06883,ko:K06946	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	DUF697,MMR_HSR1
WZS2_k127_9937054_11	926569.ANT_03150	1.68e-128	418.0	COG1208@1|root,COG1208@2|Bacteria,2G5KH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WZS2_k127_9937054_9	357808.RoseRS_3240	3.22e-148	481.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,374TY@32061|Chloroflexia	32061|Chloroflexia	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS2_k127_9937054_5	926569.ANT_24690	1.965e-180	576.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WZS2_k127_9937054_22	926569.ANT_03010	7.857e-35	139.0	COG3118@1|root,COG3118@2|Bacteria,2G70B@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function (DUF2892)	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	DUF2892,Thioredoxin
WZS2_k127_9937054_26	309801.trd_0152	2.034e-17	85.0	2EQM1@1|root,33I6Z@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
WZS2_k127_9937054_4	926569.ANT_12440	9.665e-197	624.0	COG0137@1|root,COG0137@2|Bacteria,2G5ME@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the argininosuccinate synthase family. Type	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
WZS2_k127_9937054_6	926569.ANT_12430	2.106e-166	535.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi	200795|Chloroflexi	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
WZS2_k127_9937054_27	926569.ANT_12420	1.203e-16	82.0	2DRHT@1|root,33BTG@2|Bacteria,2G7I1@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
WZS2_k127_9937054_12	926569.ANT_12410	1.318e-127	414.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi	200795|Chloroflexi	HJ	Belongs to the RimK family	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
WZS2_k127_9937054_7	926569.ANT_12400	5.746e-152	488.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WZS2_k127_9937054_14	383372.Rcas_3466	7.286e-100	332.0	COG0548@1|root,COG0548@2|Bacteria,2G5WV@200795|Chloroflexi,375DI@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the acetylglutamate kinase family. LysZ subfamily	lysZ	-	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
WZS2_k127_9937054_8	926569.ANT_12380	6.653e-151	486.0	COG4992@1|root,COG4992@2|Bacteria,2G5SG@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine	lysJ	-	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Peptidase_M20
WZS2_k127_9937054_13	926569.ANT_12370	1.891e-100	338.0	COG0624@1|root,COG0624@2|Bacteria,2G61X@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
WZS2_k127_9937054_1	926569.ANT_06270	2.73e-225	704.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS2_k127_9937054_10	926569.ANT_27130	3.808e-138	449.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi	200795|Chloroflexi	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WZS2_k127_9937054_0	926569.ANT_27120	3.761e-310	968.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
WZS2_k127_9937054_16	926569.ANT_28360	7.408e-91	303.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
WZS2_k127_9937054_3	926569.ANT_03160	1.309e-202	645.0	COG1164@1|root,COG1164@2|Bacteria,2G5SV@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
WZS2_k127_9937054_29	468059.AUHA01000002_gene632	2.072e-05	49.0	2DGHH@1|root,2ZW0G@2|Bacteria,4P7TH@976|Bacteroidetes,1IZEV@117747|Sphingobacteriia	976|Bacteroidetes	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
WZS2_k127_9937054_2	926569.ANT_03170	3.302e-215	677.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS2_k127_9937054_24	717605.Theco_2917	1.369e-27	114.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WZS2_k127_9937054_25	1173021.ALWA01000021_gene696	8.57e-22	107.0	COG0627@1|root,COG0627@2|Bacteria,1GQCZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
WZS2_k127_9937054_15	926569.ANT_30890	3.184e-94	324.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
WZS2_k127_9988549_2	290315.Clim_0863	5.085e-81	276.0	COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi	1090|Chlorobi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
WZS2_k127_9988549_5	1123368.AUIS01000030_gene1253	3.894e-28	116.0	COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,1SE9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
WZS2_k127_9988549_0	926569.ANT_07890	1.157e-121	406.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS2_k127_9988549_1	926569.ANT_07900	5.712e-93	310.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_07900|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9988549_3	926569.ANT_15670	3.262e-66	248.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS2_k127_9988549_4	1410620.SHLA_46c000250	5.621e-53	199.0	COG0524@1|root,COG0524@2|Bacteria,1Q2F5@1224|Proteobacteria,2V669@28211|Alphaproteobacteria,4BIVF@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WZS2_k127_9988549_6	316274.Haur_0761	8.698e-08	55.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA,PMT_2
## 2028 queries scanned
## Total time (seconds): 290.14879727363586
## Rate: 6.99 q/s