## Fri Feb 20 01:38:51 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/WZS3_bin.14.fa -m mmseqs --output WZS3_bin.14 --output_dir /data/result/bins/wyx/eggqs50+/WZS3_bin.14 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WZS3_k127_1024169_1	1007103.AFHW01000094_gene3201	8.306e-74	259.0	COG3172@1|root,COG3172@2|Bacteria,1TQ29@1239|Firmicutes,4HBZT@91061|Bacilli,26SKF@186822|Paenibacillaceae	91061|Bacilli	H	Cytidyltransferase	-	-	2.7.1.22,2.7.7.1	ko:K06211	ko00760,ko01100,map00760,map01100	-	R00137,R02324,R03005	RC00002,RC00017	ko00000,ko00001,ko01000,ko03000	-	-	-	AAA_28,CTP_transf_like
WZS3_k127_1024169_0	1541960.KQ78_01082	5.953e-129	417.0	COG1131@1|root,COG1131@2|Bacteria,3WSYM@544448|Tenericutes	544448|Tenericutes	V	AAA domain, putative AbiEii toxin, Type IV TA system	yxlF_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_tran
WZS3_k127_1024169_2	1117379.BABA_11101	2.499e-07	53.0	COG1277@1|root,COG1277@2|Bacteria,1TRD6@1239|Firmicutes,4HGGV@91061|Bacilli,1ZC8J@1386|Bacillus	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WZS3_k127_1027887_1	340099.Teth39_0975	1.859e-94	315.0	COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,25E7N@186801|Clostridia,42EW4@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM 6-phosphogluconate dehydrogenase	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WZS3_k127_1027887_2	1131462.DCF50_p1176	2.051e-88	300.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,2620H@186807|Peptococcaceae	186801|Clostridia	I	TIGRFAM lipid kinase, YegS Rv2252 BmrU family	dagK	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
WZS3_k127_1027887_8	1307436.PBF_01400	4.949e-11	73.0	COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,4HGNR@91061|Bacilli,1ZEBH@1386|Bacillus	91061|Bacilli	S	GNAT acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_10,Acetyltransf_9,GNAT_acetyltran
WZS3_k127_1027887_3	1196029.ALIM01000002_gene4467	2.913e-86	297.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli,1ZD5Y@1386|Bacillus	91061|Bacilli	L	A G-specific	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
WZS3_k127_1027887_5	158190.SpiGrapes_1536	2.157e-67	239.0	COG2199@1|root,COG3706@2|Bacteria,2J7K5@203691|Spirochaetes	203691|Spirochaetes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WZS3_k127_1027887_6	1321778.HMPREF1982_01897	1.297e-61	219.0	2B66C@1|root,31Z3H@2|Bacteria,1V6U0@1239|Firmicutes,24ICU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1027887_4	1033810.HLPCO_001698	8.445e-84	283.0	COG3634@1|root,COG3634@2|Bacteria,2NPR2@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WZS3_k127_1027887_0	1033810.HLPCO_001697	8.401e-104	347.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384,ko:K03387	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2
WZS3_k127_1027887_7	1410668.JNKC01000001_gene1912	2.274e-14	78.0	COG1943@1|root,COG1943@2|Bacteria,1V553@1239|Firmicutes,2495R@186801|Clostridia,36F6G@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WZS3_k127_1049363_0	1391646.AVSU01000029_gene2631	9.414e-217	675.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,25QE3@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WZS3_k127_1049363_1	1499684.CCNP01000020_gene2532	4.699e-155	499.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,36E77@31979|Clostridiaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WZS3_k127_1049363_2	592015.HMPREF1705_01076	7.143e-16	85.0	COG2385@1|root,COG2385@2|Bacteria,3T9PB@508458|Synergistetes	508458|Synergistetes	D	SpoIID LytB domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
WZS3_k127_1057021_0	293826.Amet_3032	3.26e-94	315.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,36E2C@31979|Clostridiaceae	186801|Clostridia	S	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
WZS3_k127_1057021_2	1128398.Curi_c18150	4.925e-35	139.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,268WT@186813|unclassified Clostridiales	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
WZS3_k127_1057021_1	350688.Clos_1250	6.546e-75	265.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,36FWD@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
WZS3_k127_1057021_3	1122217.KB899572_gene1216	3.058e-25	106.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4H5BU@909932|Negativicutes	909932|Negativicutes	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
WZS3_k127_1116111_0	1449050.JNLE01000003_gene1727	4.746e-113	377.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,36E34@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA1	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WZS3_k127_1116111_1	1511.CLOST_0769	2.802e-28	119.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WZS3_k127_1120037_1	931276.Cspa_c30620	5.05e-57	205.0	COG3584@1|root,COG3584@2|Bacteria,1VW6B@1239|Firmicutes,24MFE@186801|Clostridia,36QRA@31979|Clostridiaceae	186801|Clostridia	S	Butirosin biosynthesis protein H, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WZS3_k127_1120037_0	1121289.JHVL01000050_gene2016	1.069e-87	297.0	COG2362@1|root,COG2362@2|Bacteria,1TSUZ@1239|Firmicutes,24CY1@186801|Clostridia,36EZF@31979|Clostridiaceae	186801|Clostridia	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
WZS3_k127_1151294_0	1443122.Z958_08160	2.551e-221	700.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,36FU3@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
WZS3_k127_1166140_1	293826.Amet_3114	1.062e-68	238.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,36DSA@31979|Clostridiaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WZS3_k127_1166140_0	941824.TCEL_01309	1.015e-145	474.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,36DX8@31979|Clostridiaceae	186801|Clostridia	E	Dipeptidase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_11683_2	386415.NT01CX_0761	4.078e-44	163.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,36GNE@31979|Clostridiaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WZS3_k127_11683_3	941824.TCEL_01285	2.259e-30	123.0	COG4109@1|root,COG4109@2|Bacteria,1VA3T@1239|Firmicutes,24MQM@186801|Clostridia,36KUH@31979|Clostridiaceae	186801|Clostridia	K	DRTGG domain	-	-	-	-	-	-	-	-	-	-	-	-	DRTGG
WZS3_k127_11683_1	1304284.L21TH_2148	1.223e-46	171.0	COG2172@1|root,COG2172@2|Bacteria,1V6YP@1239|Firmicutes,24JJ0@186801|Clostridia,36JQQ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase-like ATPase domain	RsbW	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2
WZS3_k127_11683_0	273068.TTE0887	1.347e-61	216.0	COG2000@1|root,COG2221@1|root,COG4624@1|root,COG2000@2|Bacteria,COG2221@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,24BF5@186801|Clostridia,42F1E@68295|Thermoanaerobacterales	186801|Clostridia	C	Fe-S cluster domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_9
WZS3_k127_1178884_2	509191.AEDB02000093_gene3467	4.833e-22	97.0	COG4591@1|root,COG4591@2|Bacteria,1TQ8J@1239|Firmicutes,24BJ2@186801|Clostridia	186801|Clostridia	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WZS3_k127_1178884_0	1410668.JNKC01000004_gene43	6.456e-104	341.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,36ES4@31979|Clostridiaceae	186801|Clostridia	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WZS3_k127_1178884_3	552398.HMPREF0866_02266	0.0001232	53.0	COG1388@1|root,COG4228@1|root,COG1388@2|Bacteria,COG4228@2|Bacteria,1V4N8@1239|Firmicutes,24I3E@186801|Clostridia,3WQGY@541000|Ruminococcaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_circ_N,LysM
WZS3_k127_1178884_1	1487921.DP68_16735	1.643e-61	224.0	COG1388@1|root,COG1388@2|Bacteria,1V6T1@1239|Firmicutes,24IHB@186801|Clostridia	186801|Clostridia	M	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1193655_2	536232.CLM_0931	5.917e-48	183.0	28IH1@1|root,2Z8IC@2|Bacteria,1TSE5@1239|Firmicutes,249UI@186801|Clostridia,36DYP@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF4003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4003
WZS3_k127_1193655_0	1123009.AUID01000021_gene1302	1.33e-160	511.0	COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,249TX@186801|Clostridia,267QF@186813|unclassified Clostridiales	186801|Clostridia	C	Conserved region in glutamate synthase	lldD	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
WZS3_k127_1193655_1	1007096.BAGW01000018_gene729	4.395e-103	351.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,2N6GK@216572|Oscillospiraceae	186801|Clostridia	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS3_k127_1208102_0	997350.HMPREF9129_1855	3.475e-170	552.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,22GDR@1570339|Peptoniphilaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WZS3_k127_1208102_2	1444306.JFZC01000040_gene435	2.449e-44	168.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli,26PK9@186821|Sporolactobacillaceae	91061|Bacilli	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08510	CoaE
WZS3_k127_1208102_1	293826.Amet_1578	4.474e-46	173.0	COG0730@1|root,COG0730@2|Bacteria,1TT6E@1239|Firmicutes,24MDT@186801|Clostridia,36JQJ@31979|Clostridiaceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WZS3_k127_1232657_0	1128398.Curi_c19100	1.556e-158	522.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,268AV@186813|unclassified Clostridiales	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
WZS3_k127_1237341_1	1226322.HMPREF1545_00530	4.167e-54	195.0	COG1014@1|root,COG1014@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia	186801|Clostridia	C	oxidoreductase gamma subunit	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WZS3_k127_1237341_2	903814.ELI_0278	2.326e-36	139.0	COG1144@1|root,COG1144@2|Bacteria,1VEPH@1239|Firmicutes,24S1F@186801|Clostridia	186801|Clostridia	C	oxidoreductase, delta subunit	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
WZS3_k127_1237341_0	203119.Cthe_2796	1.72e-125	409.0	COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,3WIBC@541000|Ruminococcaceae	186801|Clostridia	C	ferredoxin oxidoreductase	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WZS3_k127_1246650_0	500632.CLONEX_03936	2.349e-88	298.0	COG1131@1|root,COG1131@2|Bacteria,1UHTY@1239|Firmicutes,24JZH@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WZS3_k127_1246650_1	1121335.Clst_1409	3.046e-79	278.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia,3WJS7@541000|Ruminococcaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
WZS3_k127_1246650_2	1121324.CLIT_10c02150	4.86e-58	204.0	COG0477@1|root,COG2814@2|Bacteria,1UY64@1239|Firmicutes,249MW@186801|Clostridia	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS3_k127_1271868_0	349161.Dred_3035	2.155e-159	506.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,26192@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WZS3_k127_1271868_1	768710.DesyoDRAFT_4875	1.837e-145	465.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,263WV@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WZS3_k127_1282857_2	1301100.HG529422_gene4236	5.418e-12	66.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,36E7X@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS3_k127_1282857_1	1391646.AVSU01000017_gene3096	3.848e-87	292.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,25R18@186804|Peptostreptococcaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WZS3_k127_1282857_0	1391647.AVSV01000013_gene2762	7.569e-165	527.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,36DVG@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS3_k127_1296470_0	1408422.JHYF01000002_gene2531	2.337e-125	405.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,36F0J@31979|Clostridiaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WZS3_k127_1296470_3	1408422.JHYF01000002_gene2530	1.374e-33	132.0	COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,24N58@186801|Clostridia,36JGG@31979|Clostridiaceae	186801|Clostridia	S	small basic protein	sbp	-	-	-	-	-	-	-	-	-	-	-	DUF1290
WZS3_k127_1296470_2	1286171.EAL2_c10510	8.809e-37	147.0	COG3879@1|root,COG3879@2|Bacteria,1V0FG@1239|Firmicutes,24DRC@186801|Clostridia,25Z1C@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
WZS3_k127_1296470_1	1304284.L21TH_0618	2.94e-46	176.0	COG3879@1|root,COG3879@2|Bacteria,1V66C@1239|Firmicutes,2492Y@186801|Clostridia,36FXV@31979|Clostridiaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF881)	-	-	-	-	-	-	-	-	-	-	-	-	DUF881
WZS3_k127_1296470_5	350688.Clos_1381	4.783e-12	75.0	COG1589@1|root,COG1589@2|Bacteria,1VEMW@1239|Firmicutes	1239|Firmicutes	D	cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
WZS3_k127_1296470_4	1321814.HMPREF9089_00605	5.865e-33	135.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,25VJ9@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WZS3_k127_1297723_4	545697.HMPREF0216_02249	3.855e-09	59.0	COG1247@1|root,COG1247@2|Bacteria,1UIRW@1239|Firmicutes,25EQT@186801|Clostridia,36NTE@31979|Clostridiaceae	186801|Clostridia	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_1297723_3	1414720.CBYM010000001_gene821	1.544e-12	71.0	COG1247@1|root,COG1247@2|Bacteria,1UIRW@1239|Firmicutes,25EQT@186801|Clostridia,36NTE@31979|Clostridiaceae	186801|Clostridia	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_1297723_0	1408422.JHYF01000007_gene1304	4.155e-223	706.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,36UQE@31979|Clostridiaceae	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind
WZS3_k127_1297723_1	350688.Clos_0389	1.397e-124	419.0	COG4191@1|root,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,249I4@186801|Clostridia,36GPP@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,dCache_1,sCache_2
WZS3_k127_1297723_2	350688.Clos_0388	4.454e-86	291.0	COG0745@1|root,COG0745@2|Bacteria,1V0JV@1239|Firmicutes,24DBU@186801|Clostridia,36IXU@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_1299737_1	903814.ELI_1210	2.019e-80	273.0	COG4662@1|root,COG4662@2|Bacteria,1TRK7@1239|Firmicutes,249VG@186801|Clostridia,25YHP@186806|Eubacteriaceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
WZS3_k127_1299737_0	350688.Clos_2434	3.941e-97	324.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,36ERE@31979|Clostridiaceae	186801|Clostridia	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WZS3_k127_1299737_2	666686.B1NLA3E_11430	4.045e-57	210.0	COG2207@1|root,COG2207@2|Bacteria,1TT76@1239|Firmicutes,4HB3S@91061|Bacilli,1ZB34@1386|Bacillus	91061|Bacilli	K	AraC-type transcriptional regulator N-terminus	lacR	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
WZS3_k127_1306806_1	1286171.EAL2_c09640	4.336e-73	265.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,25WDF@186806|Eubacteriaceae	186801|Clostridia	D	Stage II sporulation protein	lytB	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	PG_binding_1,SpoIID,Y_Y_Y
WZS3_k127_1306806_0	865861.AZSU01000003_gene1560	9.136e-146	469.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,36E7R@31979|Clostridiaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WZS3_k127_1306806_2	720554.Clocl_1225	2.258e-41	159.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WZS3_k127_1310838_4	1123009.AUID01000003_gene1867	0.0002547	45.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,26BIS@186813|unclassified Clostridiales	186801|Clostridia	M	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
WZS3_k127_1310838_0	931626.Awo_c20870	8.507e-230	728.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,25VSZ@186806|Eubacteriaceae	186801|Clostridia	GM	CoA-binding domain	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
WZS3_k127_1310838_2	935837.JAEK01000001_gene2296	7.94e-44	171.0	COG1493@1|root,COG1493@2|Bacteria,1V4IV@1239|Firmicutes,4HGBQ@91061|Bacilli,1ZCAB@1386|Bacillus	91061|Bacilli	T	Serine kinase of the HPr protein, regulates carbohydrate metabolism	hprK3	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Hpr_kinase_C
WZS3_k127_1310838_1	44251.PDUR_05225	1.691e-62	221.0	COG1132@1|root,COG1132@2|Bacteria,1TRJF@1239|Firmicutes,4HVVM@91061|Bacilli,2722N@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WZS3_k127_1322925_1	1195236.CTER_2228	4.62e-83	287.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3WGR3@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
WZS3_k127_1322925_3	1511.CLOST_1199	7.836e-51	184.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia	186801|Clostridia	O	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
WZS3_k127_1322925_2	1211817.CCAT010000045_gene2967	6.824e-80	275.0	COG0566@1|root,COG0566@2|Bacteria,1VRE3@1239|Firmicutes,24FPE@186801|Clostridia,36HQB@31979|Clostridiaceae	186801|Clostridia	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
WZS3_k127_1322925_0	1267580.AF6_2122	0.0	1016.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,21V4C@150247|Anoxybacillus	91061|Bacilli	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WZS3_k127_1322925_4	591001.Acfer_0224	1.758e-10	66.0	COG1512@1|root,COG1512@2|Bacteria,1V5YF@1239|Firmicutes,4H1Z7@909932|Negativicutes	909932|Negativicutes	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
WZS3_k127_1338155_0	1408422.JHYF01000013_gene482	3.345e-81	287.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
WZS3_k127_1338155_1	293826.Amet_3713	5.845e-57	205.0	COG3332@1|root,COG3332@2|Bacteria,1UYHE@1239|Firmicutes,24I1W@186801|Clostridia	186801|Clostridia	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
WZS3_k127_1339359_4	1122143.AUEG01000007_gene1548	1.793e-53	191.0	COG0438@1|root,COG0438@2|Bacteria,1TR2W@1239|Firmicutes,4HCY9@91061|Bacilli,27HDM@186828|Carnobacteriaceae	91061|Bacilli	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
WZS3_k127_1339359_2	1121422.AUMW01000015_gene2568	5.379e-181	572.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,26147@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
WZS3_k127_1339359_3	1121422.AUMW01000015_gene2569	2.04e-99	326.0	COG0110@1|root,COG0110@2|Bacteria,1TT21@1239|Firmicutes,24CCH@186801|Clostridia,2616C@186807|Peptococcaceae	186801|Clostridia	M	PFAM Bacterial transferase hexapeptide (three repeats)	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
WZS3_k127_1339359_1	1123009.AUID01000033_gene1338	4.409e-195	612.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,26A95@186813|unclassified Clostridiales	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WZS3_k127_1339359_0	1160707.AJIK01000040_gene2306	2.231e-243	756.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,26EAZ@186818|Planococcaceae	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	wecC	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
WZS3_k127_1339359_5	1410634.JHVD01000023_gene2029	2.808e-39	153.0	COG0438@1|root,COG0438@2|Bacteria,2HESX@201174|Actinobacteria,4DV9D@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
WZS3_k127_1340194_1	1536772.R70723_22175	8.497e-44	161.0	COG0488@1|root,COG0488@2|Bacteria,1TSB8@1239|Firmicutes,4HV4R@91061|Bacilli,26R3A@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran
WZS3_k127_1340194_0	360911.EAT1b_1425	1.552e-114	379.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,4HAM3@91061|Bacilli	91061|Bacilli	E	Threonine aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
WZS3_k127_1340194_2	221027.JO40_08920	1.523e-21	100.0	COG0454@1|root,COG0456@2|Bacteria,2J8DV@203691|Spirochaetes	203691|Spirochaetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_1346720_1	931626.Awo_c05840	3.276e-43	161.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia,25VWR@186806|Eubacteriaceae	186801|Clostridia	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WZS3_k127_1346720_0	694427.Palpr_2170	4.333e-50	190.0	COG0642@1|root,COG0745@1|root,COG2770@1|root,COG3437@1|root,COG3605@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,4NDXU@976|Bacteroidetes,2FM06@200643|Bacteroidia,22XHH@171551|Porphyromonadaceae	976|Bacteroidetes	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K20971,ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GAF,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12,TPR_8
WZS3_k127_1372472_1	420246.GTNG_0443	2.136e-144	471.0	COG0397@1|root,COG0397@2|Bacteria,1TQXD@1239|Firmicutes,4HBKH@91061|Bacilli,1WG0D@129337|Geobacillus	91061|Bacilli	S	Uncharacterized ACR, YdiU/UPF0061 family	M1-1044	-	-	-	-	-	-	-	-	-	-	-	UPF0061
WZS3_k127_1372472_0	858215.Thexy_0238	5.75e-163	517.0	COG4638@1|root,COG4638@2|Bacteria,1UYZZ@1239|Firmicutes,248NK@186801|Clostridia	186801|Clostridia	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rieske
WZS3_k127_1372472_3	645991.Sgly_1414	4.513e-49	177.0	COG1433@1|root,COG1433@2|Bacteria,1V74Q@1239|Firmicutes,24KWR@186801|Clostridia,265B5@186807|Peptococcaceae	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WZS3_k127_1372472_2	2325.TKV_c01910	5.871e-106	350.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,42FWZ@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5
WZS3_k127_1372472_4	2325.TKV_c01900	1.845e-30	126.0	COG0348@1|root,COG0348@2|Bacteria,1V8RW@1239|Firmicutes,24JXS@186801|Clostridia,42GUZ@68295|Thermoanaerobacterales	186801|Clostridia	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1384277_1	509191.AEDB02000108_gene1608	1.257e-50	181.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_1384277_0	509191.AEDB02000108_gene1609	8.278e-163	530.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,3WHII@541000|Ruminococcaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WZS3_k127_1384277_2	1211817.CCAT010000012_gene2844	1.562e-49	186.0	COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia,36G4J@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
WZS3_k127_13965_1	768704.Desmer_2989	1.078e-49	181.0	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,24973@186801|Clostridia,264ZD@186807|Peptococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_13965_0	1163671.JAGI01000002_gene3766	2.053e-54	208.0	COG0642@1|root,COG2205@2|Bacteria,1UYC9@1239|Firmicutes,24CPQ@186801|Clostridia,36GIS@31979|Clostridiaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_1407801_2	1121289.JHVL01000023_gene77	2.041e-51	185.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,36DMV@31979|Clostridiaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
WZS3_k127_1407801_1	1031288.AXAA01000018_gene22	7.859e-199	646.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,36DF4@31979|Clostridiaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
WZS3_k127_1407801_0	1304284.L21TH_0782	1.213e-318	987.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,36DFR@31979|Clostridiaceae	186801|Clostridia	J	elongation factor G	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WZS3_k127_1424494_2	1347392.CCEZ01000025_gene3226	1.261e-11	65.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,36DCJ@31979|Clostridiaceae	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
WZS3_k127_1424494_1	1410668.JNKC01000006_gene707	8.373e-270	840.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36DEY@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_1424494_0	1410668.JNKC01000006_gene708	4.049e-281	875.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_1425182_0	1286171.EAL2_808p00290	3.66e-189	610.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,25VFA@186806|Eubacteriaceae	186801|Clostridia	S	UPF0182 protein	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
WZS3_k127_1425182_3	189425.PGRAT_22775	9.228e-14	78.0	2BZDM@1|root,2ZVDC@2|Bacteria,1W4H9@1239|Firmicutes,4I8M5@91061|Bacilli,2704I@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1425182_1	573061.Clocel_0901	3.218e-102	338.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,36EMS@31979|Clostridiaceae	186801|Clostridia	T	response regulator	-	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_1425182_2	931626.Awo_c30360	1.601e-28	119.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,25VYA@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K19081	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
WZS3_k127_1430888_3	1408422.JHYF01000016_gene134	1.513e-09	64.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
WZS3_k127_1430888_1	1121289.JHVL01000005_gene927	3.401e-46	174.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,36I39@31979|Clostridiaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WZS3_k127_1430888_0	857293.CAAU_2325	8.17e-49	184.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,36EKU@31979|Clostridiaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WZS3_k127_1430888_2	203119.Cthe_0684	1.378e-24	117.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WZS3_k127_1433511_2	329726.AM1_0697	3.254e-43	166.0	COG0415@1|root,COG0415@2|Bacteria	2|Bacteria	L	Belongs to the DNA photolyase family	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
WZS3_k127_1433511_0	1123009.AUID01000030_gene1359	2.509e-207	659.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,268H8@186813|unclassified Clostridiales	186801|Clostridia	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
WZS3_k127_1433511_1	1128398.Curi_c26570	1.573e-146	474.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,267QC@186813|unclassified Clostridiales	186801|Clostridia	J	Psort location Cytoplasmic, score	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WZS3_k127_1433511_3	332101.JIBU02000075_gene3836	2.979e-24	105.0	COG1942@1|root,COG1942@2|Bacteria,1VA6U@1239|Firmicutes,24MXT@186801|Clostridia,36KV1@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF1904)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1904
WZS3_k127_1448311_0	1487921.DP68_08055	0.0	1471.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,36UMQ@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
WZS3_k127_1448311_1	545693.BMQ_0397	3.397e-31	131.0	COG0300@1|root,COG0300@2|Bacteria,1U5VD@1239|Firmicutes,4HES8@91061|Bacilli,1ZDY5@1386|Bacillus	91061|Bacilli	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
WZS3_k127_1477785_0	195103.CPF_1937	5.353e-70	246.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,36EJJ@31979|Clostridiaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
WZS3_k127_1477785_1	203119.Cthe_0989	2.704e-49	184.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WZS3_k127_1479585_1	760011.Spico_0722	4.437e-115	376.0	COG1175@1|root,COG1175@2|Bacteria,2J6AN@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WZS3_k127_1479585_0	1304866.K413DRAFT_4858	3.594e-118	388.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,36FNN@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
WZS3_k127_148427_4	1501230.ET33_05220	7.239e-32	135.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,4HBY6@91061|Bacilli,26RPU@186822|Paenibacillaceae	91061|Bacilli	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WZS3_k127_148427_0	572544.Ilyop_0441	3.24e-65	231.0	COG1489@1|root,COG1489@2|Bacteria,37918@32066|Fusobacteria	32066|Fusobacteria	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
WZS3_k127_148427_6	1121289.JHVL01000005_gene1003	5.891e-14	75.0	2DPRM@1|root,3333W@2|Bacteria,1UPZN@1239|Firmicutes,24SAT@186801|Clostridia,36NG6@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lys_export
WZS3_k127_148427_1	1511.CLOST_1285	2.088e-62	222.0	COG2431@1|root,COG2431@2|Bacteria,1V44M@1239|Firmicutes,24I3B@186801|Clostridia,25TE7@186804|Peptostreptococcaceae	186801|Clostridia	S	Pfam:DUF340	-	-	-	-	-	-	-	-	-	-	-	-	Lys_export
WZS3_k127_148427_2	596329.HMPREF0631_0667	2.436e-56	203.0	COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,24HUY@186801|Clostridia,25TAJ@186804|Peptostreptococcaceae	186801|Clostridia	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
WZS3_k127_148427_3	1511.CLOST_2402	9.117e-36	141.0	COG3467@1|root,COG3467@2|Bacteria,1V7MR@1239|Firmicutes,25B09@186801|Clostridia,25RSB@186804|Peptostreptococcaceae	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
WZS3_k127_148427_5	1120985.AUMI01000017_gene2643	1.537e-28	119.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes	1239|Firmicutes	G	Belongs to the inositol monophosphatase superfamily	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WZS3_k127_1485199_1	160799.PBOR_04035	2.274e-17	90.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26W24@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_1485199_0	34007.IT40_03315	3.896e-75	262.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2PUG9@265|Paracoccus	28211|Alphaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_1492058_0	1121289.JHVL01000019_gene638	4.409e-157	503.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,249JN@186801|Clostridia,36EXQ@31979|Clostridiaceae	186801|Clostridia	D	TIGRFAM arsenite-activated ATPase ArsA	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
WZS3_k127_1492058_4	610130.Closa_3566	4.064e-38	146.0	COG1146@1|root,COG2906@1|root,COG1146@2|Bacteria,COG2906@2|Bacteria,1UME0@1239|Firmicutes,25GFY@186801|Clostridia	186801|Clostridia	C	Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD,DUF2703
WZS3_k127_1492058_3	545694.TREPR_2385	2.198e-60	221.0	COG1088@1|root,COG1088@2|Bacteria,2J5ND@203691|Spirochaetes	203691|Spirochaetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WZS3_k127_1492058_2	994573.T472_0201360	7.948e-89	306.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,36ENR@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
WZS3_k127_1492058_1	994573.T472_0201355	1.214e-110	368.0	COG2897@1|root,COG2897@2|Bacteria,1TT5T@1239|Firmicutes,24C8N@186801|Clostridia,36H9D@31979|Clostridiaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WZS3_k127_1492058_5	1121129.KB903359_gene1338	1.914e-06	59.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,4PKEU@976|Bacteroidetes,2FKZ0@200643|Bacteroidia,22WZ3@171551|Porphyromonadaceae	976|Bacteroidetes	P	Belongs to the sulfur carrier protein TusA family	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
WZS3_k127_1495745_3	1408422.JHYF01000018_gene1775	3.093e-07	52.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,36K0M@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
WZS3_k127_1495745_0	1304880.JAGB01000001_gene360	7.514e-99	331.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WZS3_k127_1495745_2	1121289.JHVL01000013_gene1626	8.382e-60	216.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,24CMU@186801|Clostridia,36FPE@31979|Clostridiaceae	186801|Clostridia	E	DNA polymerase alpha chain like domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
WZS3_k127_1495745_1	1121289.JHVL01000013_gene1625	2.991e-79	271.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,36DI8@31979|Clostridiaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
WZS3_k127_1498635_1	1499683.CCFF01000015_gene3077	1.27e-85	296.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,36DZZ@31979|Clostridiaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
WZS3_k127_1498635_0	1280692.AUJL01000008_gene2371	2.219e-109	373.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,36DJ1@31979|Clostridiaceae	186801|Clostridia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
WZS3_k127_1498635_2	357809.Cphy_1056	2.52e-69	239.0	COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,248P6@186801|Clostridia,222ZD@1506553|Lachnoclostridium	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WZS3_k127_1499314_1	1321778.HMPREF1982_00784	3.42e-99	334.0	COG3214@1|root,COG3214@2|Bacteria,1TSHT@1239|Firmicutes,24BAH@186801|Clostridia	186801|Clostridia	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
WZS3_k127_1499314_2	871963.Desdi_2022	9.526e-26	110.0	COG2832@1|root,COG2832@2|Bacteria,1V6I1@1239|Firmicutes,24U8T@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
WZS3_k127_1499314_0	293826.Amet_1445	8.236e-107	349.0	COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,24CKX@186801|Clostridia,36GSW@31979|Clostridiaceae	186801|Clostridia	S	Hemerythrin HHE cation binding domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
WZS3_k127_1500292_1	1319815.HMPREF0202_00799	2.589e-21	99.0	COG0697@1|root,COG0697@2|Bacteria,37A9N@32066|Fusobacteria	32066|Fusobacteria	EG	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_1500292_0	509191.AEDB02000109_gene4976	6.973e-155	509.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,3WGD9@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WZS3_k127_1500292_2	158189.SpiBuddy_0167	2.257e-11	68.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Cupin_7,HTH_18
WZS3_k127_1545806_1	1469948.JPNB01000001_gene2154	4.32e-127	418.0	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,24BEP@186801|Clostridia,36E65@31979|Clostridiaceae	186801|Clostridia	I	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
WZS3_k127_1545806_0	1511.CLOST_0751	5.98e-132	437.0	COG2199@1|root,COG4564@1|root,COG2199@2|Bacteria,COG4564@2|Bacteria,1TPJW@1239|Firmicutes,248VA@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_2,sCache_2
WZS3_k127_1547992_3	1391646.AVSU01000057_gene1239	0.0001618	50.0	COG3012@1|root,COG3012@2|Bacteria,1V8NE@1239|Firmicutes,25DYY@186801|Clostridia,25UNI@186804|Peptostreptococcaceae	186801|Clostridia	S	helix-turn-helix, Psq domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_psq,SEC-C
WZS3_k127_1547992_0	1408422.JHYF01000002_gene2402	1.939e-80	283.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,36G1Z@31979|Clostridiaceae	186801|Clostridia	J	Threonyl alanyl tRNA synthetase SAD	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WZS3_k127_1547992_1	1122927.KB895414_gene5369	4.567e-79	274.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,4HA1B@91061|Bacilli,26SFD@186822|Paenibacillaceae	91061|Bacilli	I	Alpha beta hydrolase	yju3	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
WZS3_k127_1547992_2	1304880.JAGB01000001_gene818	3.015e-47	176.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WZS3_k127_155222_2	203119.Cthe_0730	4.241e-40	154.0	COG1285@1|root,COG1285@2|Bacteria,1V1GI@1239|Firmicutes,24G1I@186801|Clostridia,3WIHZ@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
WZS3_k127_155222_0	755731.Clo1100_3154	8.392e-90	302.0	COG5036@1|root,COG5036@2|Bacteria,1V1FZ@1239|Firmicutes,24FRH@186801|Clostridia,36I9C@31979|Clostridiaceae	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
WZS3_k127_155222_1	1209989.TepiRe1_2200	3.237e-81	274.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,42G7G@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM response regulator receiver	mprA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_160179_15	586416.GZ22_03825	4.489e-07	52.0	COG3339@1|root,COG3339@2|Bacteria,1VG4I@1239|Firmicutes,4HPVJ@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
WZS3_k127_160179_5	666686.B1NLA3E_09175	2.172e-77	264.0	COG2364@1|root,COG2364@2|Bacteria,1V47R@1239|Firmicutes,4HGYQ@91061|Bacilli,1ZG36@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	YitT_membrane
WZS3_k127_160179_7	333138.LQ50_16405	6.164e-45	167.0	COG0454@1|root,COG0456@2|Bacteria,1VESJ@1239|Firmicutes,4HQRT@91061|Bacilli,1ZI64@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WZS3_k127_160179_16	309803.CTN_1554	8.735e-06	54.0	COG0840@1|root,COG0840@2|Bacteria,2GC78@200918|Thermotogae	200918|Thermotogae	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
WZS3_k127_160179_12	1410632.JHWW01000004_gene1699	9.318e-17	83.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,27NR8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_160179_9	1511.CLOST_2034	2.286e-41	158.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
WZS3_k127_160179_8	931626.Awo_c15370	1.125e-43	164.0	COG1846@1|root,COG1846@2|Bacteria,1VBBG@1239|Firmicutes,24N9X@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR
WZS3_k127_160179_0	357809.Cphy_1697	7.07e-159	510.0	COG0003@1|root,COG0071@1|root,COG0003@2|Bacteria,COG0071@2|Bacteria,1UKBM@1239|Firmicutes,24AYR@186801|Clostridia	186801|Clostridia	P	Arsenite-activated ATPase (ArsA)	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
WZS3_k127_160179_1	357809.Cphy_1698	7.232e-159	512.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,249JN@186801|Clostridia	186801|Clostridia	P	Arsenite-activated ATPase (ArsA)	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
WZS3_k127_160179_6	1341181.FLJC2902T_15340	4.152e-60	211.0	COG5646@1|root,COG5646@2|Bacteria,4NNPA@976|Bacteroidetes,1I1Y8@117743|Flavobacteriia,2NWCA@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WZS3_k127_160179_4	1511.CLOST_0329	8.784e-78	262.0	COG0693@1|root,COG0693@2|Bacteria,1V1CG@1239|Firmicutes,25CHN@186801|Clostridia	186801|Clostridia	S	TIGRFAM intracellular protease, PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WZS3_k127_160179_10	1033810.HLPCO_001056	1.003e-36	142.0	COG0640@1|root,COG0640@2|Bacteria,2NQ74@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
WZS3_k127_160179_11	1191523.MROS_0788	9.509e-21	93.0	COG1553@1|root,COG1553@2|Bacteria	2|Bacteria	P	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE	ychN	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
WZS3_k127_160179_14	1437824.BN940_06471	2.705e-09	58.0	COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,2VSFK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrE family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
WZS3_k127_160179_3	443143.GM18_1837	2.384e-79	277.0	28I4E@1|root,31924@2|Bacteria,1Q1I3@1224|Proteobacteria,4379Z@68525|delta/epsilon subdivisions,2WUAF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_160179_2	373903.Hore_09280	2.03e-129	427.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WB0F@53433|Halanaerobiales	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	norM	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_160179_13	1235797.C816_03117	4.065e-13	79.0	COG2173@1|root,COG2173@2|Bacteria,1VAFK@1239|Firmicutes,24P72@186801|Clostridia	186801|Clostridia	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	-	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15,YkuD
WZS3_k127_160179_17	879308.HMPREF9130_1661	1.571e-05	57.0	COG0768@1|root,COG0768@2|Bacteria,1V1CI@1239|Firmicutes,24GWI@186801|Clostridia,22G58@1570339|Peptoniphilaceae	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
WZS3_k127_1613872_3	1304880.JAGB01000002_gene1523	1.922e-07	56.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
WZS3_k127_1613872_1	1499684.CCNP01000020_gene2348	4.236e-91	310.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,36DPY@31979|Clostridiaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WZS3_k127_1613872_0	1408422.JHYF01000002_gene2523	1.207e-138	454.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,36DUY@31979|Clostridiaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS3_k127_1613872_2	1120998.AUFC01000005_gene712	1.03e-89	308.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WCI1@538999|Clostridiales incertae sedis	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WZS3_k127_1613872_4	1120978.KB894082_gene1100	2.178e-06	49.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli,27FSJ@186828|Carnobacteriaceae	91061|Bacilli	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WZS3_k127_1638374_0	1449126.JQKL01000002_gene1544	1.186e-76	271.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26A5N@186813|unclassified Clostridiales	186801|Clostridia	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
WZS3_k127_1638374_1	1121324.CLIT_2c01800	2.842e-14	84.0	COG2172@1|root,COG2172@2|Bacteria,1VMMN@1239|Firmicutes	1239|Firmicutes	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
WZS3_k127_1638374_2	1128398.Curi_c17820	1.383e-07	62.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	rsbW	-	2.7.11.1	ko:K04757,ko:K06379,ko:K08282	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
WZS3_k127_169345_1	1195236.CTER_4400	1.543e-95	319.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3WGMI@541000|Ruminococcaceae	186801|Clostridia	L	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,zf-ribbon_3,zinc_ribbon_2
WZS3_k127_169345_3	1341151.ASZU01000004_gene112	7.688e-20	93.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4IEAP@91061|Bacilli,27CAZ@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
WZS3_k127_169345_0	340099.Teth39_1289	2.028e-122	400.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,42F3W@68295|Thermoanaerobacterales	186801|Clostridia	S	enoyl-(acyl-carrier-protein) reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
WZS3_k127_169345_2	351627.Csac_1604	1.882e-20	92.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,42EZH@68295|Thermoanaerobacterales	186801|Clostridia	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WZS3_k127_1731591_1	335541.Swol_2483	2.685e-55	213.0	COG2199@1|root,COG2202@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,42KYY@68298|Syntrophomonadaceae	186801|Clostridia	T	Diguanylate cyclase with PAS PAC sensor	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_3,PAS_4
WZS3_k127_1731591_0	857293.CAAU_1956	3.899e-104	350.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,36EP2@31979|Clostridiaceae	186801|Clostridia	E	TIGRFAM cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WZS3_k127_1749141_1	293826.Amet_4130	2.866e-62	219.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,36EH4@31979|Clostridiaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
WZS3_k127_1749141_0	350688.Clos_2260	1.531e-78	276.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,36FVZ@31979|Clostridiaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
WZS3_k127_1749141_2	1121289.JHVL01000013_gene1653	6.866e-19	90.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,36DGU@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WZS3_k127_1810587_0	1304284.L21TH_1508	0.0	1278.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,36DSJ@31979|Clostridiaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
WZS3_k127_183928_3	1321778.HMPREF1982_02211	1.839e-21	96.0	2CA5H@1|root,33A7N@2|Bacteria,1U8U3@1239|Firmicutes,24WDR@186801|Clostridia	186801|Clostridia	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
WZS3_k127_183928_2	756499.Desde_3792	7.347e-92	323.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,261ZQ@186807|Peptococcaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis protein (MCP) signaling domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
WZS3_k127_183928_0	1321778.HMPREF1982_02812	9.564e-148	479.0	COG2211@1|root,COG2211@2|Bacteria,1UKKD@1239|Firmicutes,25GE3@186801|Clostridia	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS3_k127_183928_1	1414720.CBYM010000006_gene1191	2.762e-135	443.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,36DHG@31979|Clostridiaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB1	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
WZS3_k127_184938_0	293826.Amet_0953	4.839e-40	165.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,36HEA@31979|Clostridiaceae	186801|Clostridia	M	Ami_3	lytC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,CW_binding_2,Cu_amine_oxidN1,SH3_3
WZS3_k127_1851799_1	398512.JQKC01000013_gene1449	1.496e-90	304.0	COG0477@1|root,COG2814@2|Bacteria,1UY64@1239|Firmicutes,249MW@186801|Clostridia,3WPM6@541000|Ruminococcaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS3_k127_1851799_0	96561.Dole_1094	2.459e-168	551.0	COG0471@1|root,COG0490@1|root,COG0569@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,COG0569@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2MMR4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
WZS3_k127_1851799_2	1033734.CAET01000079_gene3606	2.301e-85	287.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli,1ZBMT@1386|Bacillus	91061|Bacilli	K	transcriptional	mta	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
WZS3_k127_1865092_2	1511.CLOST_1024	1.443e-44	163.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,25RCA@186804|Peptostreptococcaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
WZS3_k127_1865092_0	1321778.HMPREF1982_02894	9.651e-87	305.0	COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,248P1@186801|Clostridia	186801|Clostridia	M	Ser Thr phosphatase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WZS3_k127_1865092_1	742765.HMPREF9457_00210	1.138e-64	224.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,27W5E@189330|Dorea	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WZS3_k127_186541_0	1196322.A370_01295	9.034e-175	555.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36E1P@31979|Clostridiaceae	186801|Clostridia	C	glutamate synthase (NADPH), homotetrameric	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
WZS3_k127_186541_3	994573.T472_0217835	3.172e-112	368.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,24B28@186801|Clostridia,36GU4@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WZS3_k127_186541_2	994573.T472_0217840	1.486e-124	403.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,24A3T@186801|Clostridia,36E7Y@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
WZS3_k127_186541_1	994573.T472_0217845	8.325e-164	520.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia,36F1A@31979|Clostridiaceae	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WZS3_k127_186541_5	1297581.H919_03997	1.671e-19	92.0	COG0607@1|root,COG0607@2|Bacteria,1VB3C@1239|Firmicutes,4HKWP@91061|Bacilli,21X0I@150247|Anoxybacillus	91061|Bacilli	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WZS3_k127_186541_4	768706.Desor_4089	3.575e-106	360.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,2641K@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG2	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WZS3_k127_1880675_0	411490.ANACAC_03658	8.226e-163	518.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WZS3_k127_1880675_1	1443125.Z962_00270	1.038e-16	81.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,36ERG@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
WZS3_k127_188440_1	1408254.T458_10050	2.048e-19	93.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,26Q9W@186822|Paenibacillaceae	91061|Bacilli	EP	ABC transporter permease	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WZS3_k127_188440_0	1499683.CCFF01000014_gene3813	8.044e-59	216.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36F10@31979|Clostridiaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WZS3_k127_188440_2	1211817.CCAT010000009_gene888	0.0001527	46.0	COG0406@1|root,COG0406@2|Bacteria,1VCU1@1239|Firmicutes,24Q22@186801|Clostridia,36MB6@31979|Clostridiaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WZS3_k127_1918181_3	332101.JIBU02000048_gene3740	6.871e-69	244.0	COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,24CHQ@186801|Clostridia,36H2Z@31979|Clostridiaceae	186801|Clostridia	S	TIGRFAM RarD protein	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
WZS3_k127_1918181_4	1121333.JMLH01000001_gene1907	1.145e-50	194.0	COG1876@1|root,COG1876@2|Bacteria,1VRQ9@1239|Firmicutes,3VUDY@526524|Erysipelotrichia	526524|Erysipelotrichia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
WZS3_k127_1918181_1	565653.EGBG_02920	5.428e-202	644.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HEZY@91061|Bacilli,4B0C4@81852|Enterococcaceae	91061|Bacilli	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_1918181_0	1235793.C809_02571	1.256e-240	757.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,27I9D@186928|unclassified Lachnospiraceae	186801|Clostridia	V	overlaps another CDS with the same product name	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_1918181_2	1123009.AUID01000012_gene1684	3.188e-83	299.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,267IH@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WZS3_k127_1922741_0	1403313.AXBR01000007_gene287	4.722e-114	380.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,4HAPE@91061|Bacilli,1ZB3X@1386|Bacillus	91061|Bacilli	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	ypwA	GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
WZS3_k127_1922741_2	1408422.JHYF01000006_gene1179	1.293e-45	171.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,36I0Z@31979|Clostridiaceae	186801|Clostridia	U	PFAM SEC-C motif	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
WZS3_k127_1922741_1	1122947.FR7_3093	1.026e-52	188.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4H58U@909932|Negativicutes	909932|Negativicutes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
WZS3_k127_1933390_1	1307436.PBF_08023	9.672e-35	149.0	COG1196@1|root,COG1196@2|Bacteria,1UY85@1239|Firmicutes,4IRMN@91061|Bacilli	91061|Bacilli	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1933390_3	1380408.AVGH01000033_gene503	0.000729	44.0	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,4HQ79@91061|Bacilli	91061|Bacilli	N	homolog of the cytoplasmic domain of flagellar protein FhlB	-	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
WZS3_k127_1933390_2	398511.BpOF4_14335	4.443e-24	107.0	COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,4HP8D@91061|Bacilli,1ZFYU@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	yaaR	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
WZS3_k127_1933390_0	1291050.JAGE01000001_gene2049	1.801e-204	657.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WZS3_k127_1950657_9	1511.CLOST_1901	3.682e-06	55.0	COG2919@1|root,COG2919@2|Bacteria,1U4NU@1239|Firmicutes,25K7Z@186801|Clostridia,25U5D@186804|Peptostreptococcaceae	186801|Clostridia	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1950657_1	632245.CLP_1467	1.275e-129	420.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,36E4H@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WZS3_k127_1950657_6	293826.Amet_2888	1.369e-53	192.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,36I1C@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
WZS3_k127_1950657_3	1391646.AVSU01000092_gene404	4.385e-90	302.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,25QZI@186804|Peptostreptococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
WZS3_k127_1950657_4	1118054.CAGW01000002_gene3	1.826e-80	284.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli,26TIB@186822|Paenibacillaceae	91061|Bacilli	S	zinc protease	ymfH	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS3_k127_1950657_2	1151292.QEW_3206	1.029e-93	322.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,248J8@186801|Clostridia,25R2M@186804|Peptostreptococcaceae	186801|Clostridia	S	Peptidase M16 inactive domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
WZS3_k127_1950657_0	1292035.H476_2108	7.45e-167	530.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,25QQJ@186804|Peptostreptococcaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WZS3_k127_1950657_5	748727.CLJU_c14110	4.773e-80	289.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EG9@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_2
WZS3_k127_1950657_8	1132442.KB889752_gene3546	4.134e-19	90.0	COG3695@1|root,COG3695@2|Bacteria,1VC8H@1239|Firmicutes,4HKXS@91061|Bacilli,1ZI3E@1386|Bacillus	91061|Bacilli	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	MGMT	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
WZS3_k127_1950657_7	931276.Cspa_c23010	2.045e-37	145.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia,36DKH@31979|Clostridiaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_1952662_0	1321778.HMPREF1982_01857	1.197e-50	192.0	29D92@1|root,30070@2|Bacteria,1V50X@1239|Firmicutes,24GUJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1952662_1	1122925.KB895383_gene3408	5.806e-12	74.0	COG3064@1|root,COG3064@2|Bacteria,1VB1V@1239|Firmicutes,4HJWH@91061|Bacilli,26UKZ@186822|Paenibacillaceae	91061|Bacilli	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1955167_0	1499689.CCNN01000007_gene1947	2.248e-243	765.0	COG0143@1|root,COG0143@2|Bacteria,1V0G4@1239|Firmicutes,249DC@186801|Clostridia,36G9D@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
WZS3_k127_1973273_1	1304284.L21TH_1605	1.872e-119	389.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,36DWA@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WZS3_k127_1973273_0	350688.Clos_0452	4.884e-181	573.0	COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,24C4U@186801|Clostridia,36G9Z@31979|Clostridiaceae	186801|Clostridia	F	TIGRFAM ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC
WZS3_k127_1973465_0	1304284.L21TH_0025	5.452e-164	526.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,36DMU@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WZS3_k127_1973465_1	1304284.L21TH_0687	1.727e-12	72.0	COG2603@1|root,COG2603@2|Bacteria,1TQ8T@1239|Firmicutes,24AM7@186801|Clostridia,36GE2@31979|Clostridiaceae	186801|Clostridia	S	Rhodanese Homology Domain	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
WZS3_k127_1989925_1	1122918.KB907256_gene2223	9.775e-43	164.0	COG0664@1|root,COG0664@2|Bacteria,1V2E0@1239|Firmicutes,4HG8V@91061|Bacilli,26RP4@186822|Paenibacillaceae	91061|Bacilli	T	Cyclic nucleotide-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
WZS3_k127_1989925_0	195103.CPF_0450	3.642e-64	230.0	COG2207@1|root,COG2207@2|Bacteria,1UIRJ@1239|Firmicutes,25EQA@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2058298_0	1408422.JHYF01000001_gene3022	0.0	1034.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,36DEW@31979|Clostridiaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
WZS3_k127_2058298_1	1230342.CTM_12430	9.722e-138	445.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,36DRW@31979|Clostridiaceae	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
WZS3_k127_2067746_2	1347392.CCEZ01000009_gene2310	2.782e-39	152.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36EY7@31979|Clostridiaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
WZS3_k127_2067746_4	598659.NAMH_1485	5.464e-13	78.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,42M6B@68525|delta/epsilon subdivisions,2YN3C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WZS3_k127_2067746_5	857293.CAAU_0878	5.194e-08	60.0	COG4506@1|root,COG4506@2|Bacteria,1VGH0@1239|Firmicutes,25DMW@186801|Clostridia,36UD8@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1934
WZS3_k127_2067746_1	1304284.L21TH_0231	9.592e-64	225.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,36IAW@31979|Clostridiaceae	186801|Clostridia	K	GntR family	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WZS3_k127_2067746_0	293826.Amet_4604	1.131e-82	285.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,36DM7@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
WZS3_k127_2067746_3	1408422.JHYF01000006_gene1048	1.005e-34	139.0	COG1670@1|root,COG1670@2|Bacteria,1V97U@1239|Firmicutes,24KMQ@186801|Clostridia,36K9I@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
WZS3_k127_2080520_1	865861.AZSU01000001_gene158	1.094e-05	48.0	COG1305@1|root,COG1305@2|Bacteria,1TP7G@1239|Firmicutes,24BSB@186801|Clostridia,36EZK@31979|Clostridiaceae	186801|Clostridia	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WZS3_k127_2080520_0	1121324.CLIT_4c00380	1.587e-288	896.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,25QE6@186804|Peptostreptococcaceae	186801|Clostridia	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
WZS3_k127_2083526_0	1123009.AUID01000022_gene1388	1.561e-202	639.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GGDEF,HATPase_c,HTH_3,PAS,PAS_3,PAS_4,PAS_9
WZS3_k127_2083526_1	642492.Clole_3186	5.598e-38	157.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	Abhydrolase_1,GerE
WZS3_k127_2094183_2	1408422.JHYF01000002_gene2227	2.205e-24	104.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,36E3M@31979|Clostridiaceae	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
WZS3_k127_2094183_1	1408823.AXUS01000009_gene1940	8.996e-50	187.0	COG1073@1|root,COG1073@2|Bacteria,1V2C5@1239|Firmicutes,25EB6@186801|Clostridia,25R9V@186804|Peptostreptococcaceae	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5,Rhodanese
WZS3_k127_2094183_0	290402.Cbei_3493	3.814e-84	292.0	COG0789@1|root,COG0789@2|Bacteria,1V12J@1239|Firmicutes,24DI4@186801|Clostridia,36ECP@31979|Clostridiaceae	186801|Clostridia	K	regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_25,Methyltransf_31
WZS3_k127_2095299_1	264462.Bd0885	4.367e-12	69.0	COG1942@1|root,COG1942@2|Bacteria,1N7M2@1224|Proteobacteria,43F1E@68525|delta/epsilon subdivisions,2MUEU@213481|Bdellovibrionales,2X2ZI@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Domain of unknown function (DUF1904)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1904
WZS3_k127_2095299_0	720555.BATR1942_03710	1.148e-61	229.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,1ZC54@1386|Bacillus	91061|Bacilli	G	Polysaccharide deacetylase	yjeA	GO:0005575,GO:0016020	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,DUF4163,Polysacc_deac_1
WZS3_k127_21392_2	1301100.HG529402_gene6756	4.192e-31	127.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,36EVY@31979|Clostridiaceae	186801|Clostridia	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WZS3_k127_21392_3	1230342.CTM_00070	1.351e-05	53.0	COG5416@1|root,COG5416@2|Bacteria,1VK4W@1239|Firmicutes,24RJX@186801|Clostridia,36NC1@31979|Clostridiaceae	186801|Clostridia	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
WZS3_k127_21392_1	1121289.JHVL01000004_gene2049	1.287e-89	304.0	COG0341@1|root,COG0341@2|Bacteria,1TSZE@1239|Firmicutes,249A3@186801|Clostridia,36ETH@31979|Clostridiaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WZS3_k127_21392_0	1347392.CCEZ01000043_gene566	5.458e-122	404.0	COG0342@1|root,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,36DYW@31979|Clostridiaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
WZS3_k127_2153117_1	457396.CSBG_00906	3.503e-64	222.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,36EIV@31979|Clostridiaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_2153117_0	1408422.JHYF01000013_gene512	9.325e-70	250.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,36F4S@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_2154166_3	868595.Desca_0155	5.703e-43	158.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,26265@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
WZS3_k127_2154166_1	1304284.L21TH_1505	1.354e-101	338.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,36E8S@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
WZS3_k127_2154166_0	1408422.JHYF01000018_gene1777	1.425e-119	389.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,36EKX@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
WZS3_k127_2154166_2	1304284.L21TH_1507	1.366e-61	222.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,36FY5@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
WZS3_k127_2154166_4	877424.ATWC01000028_gene2377	1.766e-17	91.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,27IE6@186928|unclassified Lachnospiraceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
WZS3_k127_2154166_5	1504822.CCNO01000008_gene2080	2.563e-06	57.0	COG2333@1|root,COG2333@2|Bacteria,2NP4I@2323|unclassified Bacteria	2|Bacteria	U	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
WZS3_k127_2235683_0	350688.Clos_2028	2.592e-120	397.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,36E3A@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS3_k127_2235683_1	350688.Clos_2038	1.978e-80	274.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,36E1A@31979|Clostridiaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WZS3_k127_2248908_0	1487921.DP68_04595	2.683e-131	422.0	COG1578@1|root,COG1578@2|Bacteria,1UURD@1239|Firmicutes,2492C@186801|Clostridia,36GFY@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
WZS3_k127_2248908_2	994573.T472_0200200	4.586e-22	100.0	COG3976@1|root,COG3976@2|Bacteria,1VFG0@1239|Firmicutes,24RHT@186801|Clostridia,36MVQ@31979|Clostridiaceae	186801|Clostridia	S	PFAM FMN-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
WZS3_k127_2248908_1	293826.Amet_1815	1.502e-33	132.0	2CTED@1|root,32ST9@2|Bacteria,1VD31@1239|Firmicutes,24Q04@186801|Clostridia,36NGU@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2255200_1	720554.Clocl_3491	3.967e-53	195.0	COG4194@1|root,COG4194@2|Bacteria	2|Bacteria	K	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
WZS3_k127_2255200_0	1209989.TepiRe1_2203	3.561e-133	441.0	COG5337@1|root,COG5337@2|Bacteria,1U0PJ@1239|Firmicutes,248HG@186801|Clostridia,42HYV@68295|Thermoanaerobacterales	186801|Clostridia	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Cthe_2159
WZS3_k127_2255200_2	1487921.DP68_10535	6.112e-28	116.0	COG1285@1|root,COG1285@2|Bacteria,1V1GI@1239|Firmicutes,24G1I@186801|Clostridia,36HHF@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
WZS3_k127_2255382_1	350688.Clos_1829	2.195e-35	139.0	COG0457@1|root,COG0457@2|Bacteria,1V96X@1239|Firmicutes,24AK3@186801|Clostridia,36DG6@31979|Clostridiaceae	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
WZS3_k127_2255382_0	350688.Clos_1828	9.293e-112	368.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,36DC6@31979|Clostridiaceae	186801|Clostridia	C	phosphate butyryltransferase	ptb1	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
WZS3_k127_2260135_2	1157490.EL26_20440	2.049e-54	195.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HBVK@91061|Bacilli	91061|Bacilli	L	COG0513 Superfamily II DNA and RNA helicases	deaD3	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
WZS3_k127_2260135_1	82654.Pse7367_0728	1.249e-119	389.0	COG2326@1|root,COG2326@2|Bacteria,1G34U@1117|Cyanobacteria,1H708@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
WZS3_k127_2260135_0	350688.Clos_0139	9.044e-169	539.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,36E70@31979|Clostridiaceae	186801|Clostridia	C	flavodoxin nitric oxide synthase	fprA	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5,Lactamase_B
WZS3_k127_2260135_3	1541960.KQ78_01130	7.747e-47	175.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	yijE	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_2261440_2	1321778.HMPREF1982_02995	2.204e-39	153.0	COG0664@1|root,COG0664@2|Bacteria,1V5MZ@1239|Firmicutes,24AQS@186801|Clostridia,26AIC@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WZS3_k127_2261440_1	1449050.JNLE01000003_gene3369	1.284e-59	230.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,SBP_bac_3
WZS3_k127_2261440_0	1117379.BABA_02192	2.308e-143	462.0	COG1741@1|root,COG1741@2|Bacteria,1TQDV@1239|Firmicutes,4HMYE@91061|Bacilli,1ZM90@1386|Bacillus	91061|Bacilli	S	Belongs to the pirin family	-	-	-	-	-	-	-	-	-	-	-	-	Pirin,Pirin_C
WZS3_k127_2261440_3	649747.HMPREF0083_00907	6.589e-06	54.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,4H9RZ@91061|Bacilli,26W8A@186822|Paenibacillaceae	91061|Bacilli	NT	methyl-accepting chemotaxis protein McpA K03406	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_3_3
WZS3_k127_2267038_0	386415.NT01CX_0970	0.0	1075.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,36E5W@31979|Clostridiaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
WZS3_k127_2267038_1	386415.NT01CX_0968	1.291e-193	616.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,36FU3@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
WZS3_k127_2271314_1	1511.CLOST_1607	9.958e-79	269.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,25REG@186804|Peptostreptococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	artP	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WZS3_k127_2271314_2	1293054.HSACCH_00938	1.257e-75	259.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,3WBEH@53433|Halanaerobiales	186801|Clostridia	E	TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
WZS3_k127_2271314_0	195103.CPF_0583	5.482e-106	348.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
WZS3_k127_2271314_3	332101.JIBU02000012_gene1042	3.584e-48	175.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,24CDY@186801|Clostridia,36EC4@31979|Clostridiaceae	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	ko:K08161	-	-	-	-	ko00000,ko02000	2.A.1.2.20	-	-	MFS_1,Sugar_tr
WZS3_k127_2273473_0	1410668.JNKC01000005_gene2451	5.379e-86	291.0	COG0840@1|root,COG0840@2|Bacteria,1TSP5@1239|Firmicutes,24AUD@186801|Clostridia,36EC7@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HNOB,MCPsignal
WZS3_k127_2273473_1	931626.Awo_c32820	1.344e-42	175.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,25VH8@186806|Eubacteriaceae	186801|Clostridia	T	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c
WZS3_k127_2273473_2	1120998.AUFC01000001_gene1890	9.866e-15	75.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WZS3_k127_23242_0	1408422.JHYF01000006_gene1137	7.161e-222	699.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,36DJ5@31979|Clostridiaceae	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
WZS3_k127_23242_1	641107.CDLVIII_2006	4.128e-68	235.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,36WSB@31979|Clostridiaceae	186801|Clostridia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
WZS3_k127_2329701_1	755731.Clo1100_2019	3.169e-73	252.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,36DH6@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the peptidase M16 family	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS3_k127_2329701_0	1121289.JHVL01000003_gene2172	1.093e-230	728.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,36DDN@31979|Clostridiaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WZS3_k127_2332328_0	1340434.AXVA01000023_gene3358	9.503e-206	648.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,4HAIP@91061|Bacilli,1ZAPW@1386|Bacillus	91061|Bacilli	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
WZS3_k127_2332328_1	945021.TEH_12780	2.54e-114	381.0	COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,4HAB0@91061|Bacilli,4AZWB@81852|Enterococcaceae	91061|Bacilli	S	ATP-grasp domain	yxbA	-	6.3.1.12	ko:K17810	-	-	-	-	ko00000,ko01000	-	-	-	CPSase_L_D2,Dala_Dala_lig_C
WZS3_k127_2332328_2	1123290.AUDQ01000025_gene3124	5.482e-113	374.0	COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,4HC1Z@91061|Bacilli	91061|Bacilli	V	protein involved in methicillin resistance	femX	-	2.3.2.10,2.3.2.16	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	-	R08776,R08779	RC00055,RC00096	ko00000,ko00001,ko01000,ko01011	-	-	-	FemAB
WZS3_k127_2332328_3	1408424.JHYI01000036_gene2529	1.367e-64	235.0	COG4990@1|root,COG4990@2|Bacteria,1V3XE@1239|Firmicutes,4HHPK@91061|Bacilli,1ZRKI@1386|Bacillus	91061|Bacilli	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WZS3_k127_2375029_1	445973.CLOBAR_00073	1.321e-86	292.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,25QG5@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
WZS3_k127_2375029_0	1304284.L21TH_1889	4.237e-103	341.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,36G0P@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
WZS3_k127_2375029_3	1128398.Curi_c22860	8.08e-35	138.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,269S8@186813|unclassified Clostridiales	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
WZS3_k127_2375029_2	608506.COB47_2028	5.076e-48	178.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,42ETH@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WZS3_k127_2380332_3	1321778.HMPREF1982_02211	1.76e-19	88.0	2CA5H@1|root,33A7N@2|Bacteria,1U8U3@1239|Firmicutes,24WDR@186801|Clostridia	186801|Clostridia	S	Cysteine-rich CWC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CWC
WZS3_k127_2380332_2	445975.COLSTE_00497	8.121e-32	129.0	COG0607@1|root,COG0607@2|Bacteria,2HVAM@201174|Actinobacteria,4CWJY@84998|Coriobacteriia	84998|Coriobacteriia	P	Rhodanese Homology Domain	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Rhodanese
WZS3_k127_2380332_1	1408422.JHYF01000009_gene2137	9.565e-33	128.0	COG0695@1|root,COG0695@2|Bacteria,1VK60@1239|Firmicutes	1239|Firmicutes	O	Glutaredoxin	nrdH	-	-	ko:K03676,ko:K06191	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
WZS3_k127_2380332_0	1248760.ANFZ01000014_gene2173	2.642e-76	278.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K0SK@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
WZS3_k127_2384158_2	1321778.HMPREF1982_04396	1.583e-83	280.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,267J7@186813|unclassified Clostridiales	186801|Clostridia	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS3_k127_2384158_1	1321778.HMPREF1982_04395	3.034e-113	371.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,268B5@186813|unclassified Clostridiales	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WZS3_k127_2384158_0	1321778.HMPREF1982_04394	3.478e-189	598.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WZS3_k127_2388633_0	293826.Amet_3643	1.123e-187	601.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,36DT4@31979|Clostridiaceae	186801|Clostridia	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WZS3_k127_2388633_1	1391646.AVSU01000001_gene247	7.651e-12	68.0	arCOG00127@1|root,33TE0@2|Bacteria,1VQPB@1239|Firmicutes,25JM6@186801|Clostridia,25SWS@186804|Peptostreptococcaceae	186801|Clostridia	C	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2397905_1	1304284.L21TH_1288	3.48e-126	414.0	COG0524@1|root,COG1522@1|root,COG0524@2|Bacteria,COG1522@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,36F1Z@31979|Clostridiaceae	186801|Clostridia	G	hmm pf00294	rbsK	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
WZS3_k127_2397905_0	350688.Clos_0652	1.195e-153	489.0	COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,247J8@186801|Clostridia,36F77@31979|Clostridiaceae	186801|Clostridia	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
WZS3_k127_2397905_2	1121344.JHZO01000006_gene1838	9.826e-77	267.0	COG0834@1|root,COG3437@1|root,COG0834@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes	1239|Firmicutes	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,HisKA_7TM,PAS,PAS_3,PAS_4,PAS_9
WZS3_k127_2398144_3	1033810.HLPCO_000682	5.223e-24	105.0	COG0366@1|root,COG0366@2|Bacteria,2NP2D@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	nplT	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_N,DUF3459,Malt_amylase_C
WZS3_k127_2398144_1	1499684.CCNP01000018_gene935	3.065e-70	253.0	COG1396@1|root,COG1396@2|Bacteria,1VBK2@1239|Firmicutes,24N6F@186801|Clostridia,36HF4@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TPR_8
WZS3_k127_2398144_0	536227.CcarbDRAFT_0404	5.495e-206	651.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,36DWR@31979|Clostridiaceae	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
WZS3_k127_2398144_2	1304284.L21TH_1160	3.063e-55	201.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,36EQD@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
WZS3_k127_2418217_2	1033810.HLPCO_001260	1.724e-39	153.0	COG1554@1|root,COG1554@2|Bacteria,2NQBQ@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 65, C-terminal domain	treP	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
WZS3_k127_2418217_1	1033810.HLPCO_001261	1.193e-114	375.0	COG0395@1|root,COG0395@2|Bacteria,2NPBC@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10238	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
WZS3_k127_2418217_0	345219.Bcoa_0679	2.731e-119	396.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,4HBIM@91061|Bacilli,1ZDUQ@1386|Bacillus	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WZS3_k127_2418217_3	1089548.KI783301_gene299	0.000408	43.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,4HA0U@91061|Bacilli	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
WZS3_k127_2428378_2	1304284.L21TH_1561	4.435e-31	127.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,36H10@31979|Clostridiaceae	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
WZS3_k127_2428378_1	903814.ELI_0783	1.231e-56	203.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,25WWS@186806|Eubacteriaceae	186801|Clostridia	H	Adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
WZS3_k127_2428378_0	1304284.L21TH_1193	1.922e-90	304.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,36EEP@31979|Clostridiaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WZS3_k127_2428378_3	1128398.Curi_c24610	7.851e-22	95.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,268QW@186813|unclassified Clostridiales	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WZS3_k127_2462054_3	1304284.L21TH_0866	6.501e-33	137.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,36UHP@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
WZS3_k127_2462054_0	1304284.L21TH_0867	1.023e-114	376.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,36EJN@31979|Clostridiaceae	186801|Clostridia	S	PSP1 domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
WZS3_k127_2462054_1	350688.Clos_2669	2.597e-89	301.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,36F66@31979|Clostridiaceae	186801|Clostridia	S	Methyltransferase	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
WZS3_k127_2462054_2	293826.Amet_0091	3.141e-86	291.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,36E3K@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WZS3_k127_2462092_1	1499689.CCNN01000006_gene371	1.599e-73	253.0	COG2267@1|root,COG2267@2|Bacteria,1TSC4@1239|Firmicutes,24DBP@186801|Clostridia	186801|Clostridia	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS3_k127_2462092_0	1304284.L21TH_1635	6.531e-86	292.0	COG2267@1|root,COG2267@2|Bacteria,1V049@1239|Firmicutes,25F0M@186801|Clostridia,36UU9@31979|Clostridiaceae	186801|Clostridia	I	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS3_k127_2462092_2	445973.CLOBAR_00068	7.516e-33	136.0	COG1191@1|root,COG1191@2|Bacteria,1V5E6@1239|Firmicutes,24I8Q@186801|Clostridia,25TMT@186804|Peptostreptococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigI	GO:0000988,GO:0000990,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03093	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
WZS3_k127_2462092_3	138119.DSY4883	1.745e-10	73.0	COG5183@1|root,COG5183@2|Bacteria,1UIFZ@1239|Firmicutes,25EME@186801|Clostridia,267BQ@186807|Peptococcaceae	186801|Clostridia	A	Anti-sigma factor N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RsgI_N
WZS3_k127_2472920_0	1195236.CTER_1039	8.893e-46	168.0	COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,24A04@186801|Clostridia,3WN1N@541000|Ruminococcaceae	186801|Clostridia	G	PTS system	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
WZS3_k127_2472920_2	411490.ANACAC_00567	6.335e-12	66.0	COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,24A04@186801|Clostridia	186801|Clostridia	G	PTS system mannitol-specific	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
WZS3_k127_2472920_1	1392502.JNIO01000008_gene2812	1.257e-45	174.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H3C0@909932|Negativicutes	909932|Negativicutes	GKT	PRD domain protein	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,PRD,PTS_EIIA_2,PTS_IIB
WZS3_k127_2477952_2	1195236.CTER_2209	1.375e-23	101.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3WGRD@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
WZS3_k127_2477952_1	273068.TTE1376	1.619e-54	196.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,42GR6@68295|Thermoanaerobacterales	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WZS3_k127_2477952_0	500633.CLOHIR_01232	1.348e-94	317.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,25QPV@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
WZS3_k127_2485859_2	1219084.AP014508_gene688	2.143e-74	269.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
WZS3_k127_2485859_1	1195236.CTER_3098	3.72e-131	427.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,249F8@186801|Clostridia,3WHU6@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	Acetyltransf_1,RsgA_GTPase
WZS3_k127_2485859_3	1391647.AVSV01000027_gene2866	5.723e-72	249.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,36WUQ@31979|Clostridiaceae	186801|Clostridia	S	RelA SpoT	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
WZS3_k127_2485859_0	1511.CLOST_0769	9.277e-163	529.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WZS3_k127_2502529_0	1499689.CCNN01000006_gene711	3.024e-154	507.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
WZS3_k127_2502529_1	1033737.CAEV01000091_gene1993	4.428e-99	339.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
WZS3_k127_2522032_1	573061.Clocel_4117	6.648e-97	325.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,36DZN@31979|Clostridiaceae	186801|Clostridia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WZS3_k127_2522032_0	1415774.U728_468	2.792e-113	379.0	COG1457@1|root,COG1457@2|Bacteria,1TTBN@1239|Firmicutes,248EP@186801|Clostridia,36FDK@31979|Clostridiaceae	186801|Clostridia	F	Permease for cytosine/purines, uracil, thiamine, allantoin	cytX	-	-	-	-	-	-	-	-	-	-	-	Transp_cyt_pur
WZS3_k127_2522032_2	1519439.JPJG01000059_gene1984	2.075e-40	153.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,2N6DR@216572|Oscillospiraceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
WZS3_k127_2526011_1	1280689.AUJC01000003_gene1037	7.614e-51	188.0	COG1940@1|root,COG1940@2|Bacteria,1UZ80@1239|Firmicutes,25B8D@186801|Clostridia,36WBA@31979|Clostridiaceae	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WZS3_k127_2526011_0	1410625.JHWK01000002_gene317	7.549e-90	308.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia,27IVK@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_2526011_2	469618.FVAG_00432	6.227e-14	74.0	COG2017@1|root,COG2017@2|Bacteria,379TB@32066|Fusobacteria	32066|Fusobacteria	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
WZS3_k127_2527326_0	1304880.JAGB01000001_gene712	9.763e-101	334.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
WZS3_k127_2527326_1	546269.HMPREF0389_00920	3.144e-59	209.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,247UT@186801|Clostridia,25SWE@186804|Peptostreptococcaceae	186801|Clostridia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
WZS3_k127_2527326_2	946235.CAER01000070_gene2759	3.123e-31	127.0	COG1695@1|root,COG1695@2|Bacteria,1V85H@1239|Firmicutes,4HJMF@91061|Bacilli,23KRB@182709|Oceanobacillus	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WZS3_k127_2527326_3	743719.PaelaDRAFT_1248	6.699e-16	89.0	COG0604@1|root,COG0604@2|Bacteria,1TT5J@1239|Firmicutes,4HCXG@91061|Bacilli,26X69@186822|Paenibacillaceae	91061|Bacilli	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2527326_4	1214101.BN159_5646	6.359e-07	56.0	COG0346@1|root,COG0346@2|Bacteria,2IHXI@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
WZS3_k127_2527326_5	1211817.CCAT010000062_gene4048	0.000601	43.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,2495Q@186801|Clostridia,36FJZ@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
WZS3_k127_2529717_1	1128398.Curi_c18100	6.676e-90	303.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,2680T@186813|unclassified Clostridiales	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WZS3_k127_2529717_0	1121324.CLIT_11c01180	1.633e-147	480.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WZS3_k127_2529717_2	1286171.EAL2_c14240	6.89e-24	111.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,25WGP@186806|Eubacteriaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
WZS3_k127_2530419_2	293826.Amet_2206	1.811e-56	200.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,36DP3@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
WZS3_k127_2530419_0	1304284.L21TH_0439	1.451e-193	644.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,36UN0@31979|Clostridiaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WZS3_k127_2530419_1	1128398.Curi_c10370	5.418e-122	404.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,267UM@186813|unclassified Clostridiales	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WZS3_k127_2536494_1	1304284.L21TH_1509	2.639e-60	213.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,36FNS@31979|Clostridiaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
WZS3_k127_2536494_0	1304284.L21TH_0746	7.96e-209	661.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,2486F@186801|Clostridia,36F8B@31979|Clostridiaceae	186801|Clostridia	O	Negative regulator of genetic competence clpC mecB	-	-	-	ko:K03697	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small
WZS3_k127_2536728_0	1347392.CCEZ01000020_gene935	1.309e-231	730.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,36F91@31979|Clostridiaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WZS3_k127_254751_0	293826.Amet_1004	6.025e-214	684.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,36E3M@31979|Clostridiaceae	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
WZS3_k127_254751_1	1304284.L21TH_0598	3.758e-115	385.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,36FHQ@31979|Clostridiaceae	186801|Clostridia	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
WZS3_k127_2557150_0	877424.ATWC01000002_gene2829	5.983e-132	433.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,27IK5@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Uncharacterized protein family UPF0004	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
WZS3_k127_2557150_1	1280689.AUJC01000003_gene1221	1.484e-27	115.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,36DGZ@31979|Clostridiaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
WZS3_k127_26050_2	1151292.QEW_1849	2.369e-14	74.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,25QXV@186804|Peptostreptococcaceae	186801|Clostridia	EH	Peptidase C26	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17720	GATase
WZS3_k127_26050_1	545243.BAEV01000047_gene3674	4.074e-44	169.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,36DMY@31979|Clostridiaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
WZS3_k127_26050_0	332101.JIBU02000023_gene4748	6.698e-96	318.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,36DMY@31979|Clostridiaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
WZS3_k127_2637273_4	411468.CLOSCI_01653	8.191e-05	48.0	COG1668@1|root,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,21Z3E@1506553|Lachnoclostridium	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
WZS3_k127_2637273_3	1122917.KB899665_gene3946	1.876e-36	145.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,26TQ1@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WZS3_k127_2637273_0	1121324.CLIT_10c05030	6.355e-157	505.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25QZN@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase	aspC	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS3_k127_2637273_1	1121324.CLIT_10c05150	7.909e-79	278.0	COG3290@1|root,COG3290@2|Bacteria,1TQNZ@1239|Firmicutes,249FI@186801|Clostridia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K07717	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
WZS3_k127_2637273_2	1121324.CLIT_10c05140	4.847e-46	174.0	COG4753@1|root,COG4753@2|Bacteria,1TPFP@1239|Firmicutes,24AIA@186801|Clostridia	186801|Clostridia	T	YcbB domain	-	-	-	ko:K07719	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,YcbB
WZS3_k127_264349_0	1511.CLOST_0610	1.214e-77	280.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25SUT@186804|Peptostreptococcaceae	186801|Clostridia	NT	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
WZS3_k127_2674849_2	293826.Amet_1724	4.075e-32	131.0	COG1247@1|root,COG1247@2|Bacteria,1VYW2@1239|Firmicutes,2545A@186801|Clostridia,36SJ1@31979|Clostridiaceae	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_2674849_1	1286171.EAL2_808p05490	9.362e-58	206.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,25VMY@186806|Eubacteriaceae	186801|Clostridia	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
WZS3_k127_2674849_0	1121324.CLIT_2c02640	4.059e-271	845.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
WZS3_k127_2674849_3	1235802.C823_03556	8.25e-22	101.0	COG0494@1|root,COG0494@2|Bacteria,1V27D@1239|Firmicutes,24GB6@186801|Clostridia,25X0B@186806|Eubacteriaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WZS3_k127_2675299_4	1321778.HMPREF1982_04285	1.07e-20	94.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
WZS3_k127_2675299_2	1382315.JPOI01000001_gene930	6.578e-100	330.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli,1WFNQ@129337|Geobacillus	91061|Bacilli	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WZS3_k127_2675299_5	1111134.HMPREF1253_1622	1.114e-20	93.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,22HIT@1570339|Peptoniphilaceae	186801|Clostridia	G	phosphocarrier, HPr family	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
WZS3_k127_2675299_1	742740.HMPREF9474_02016	1.128e-188	599.0	COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,248JR@186801|Clostridia,21ZTC@1506553|Lachnoclostridium	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K19956	ko00051,map00051	-	R03234	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WZS3_k127_2675299_3	610130.Closa_3974	8.656e-78	270.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,220JP@1506553|Lachnoclostridium	186801|Clostridia	H	pfkB family carbohydrate kinase	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WZS3_k127_2675299_0	484770.UFO1_0940	3.427e-199	638.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,4H313@909932|Negativicutes	909932|Negativicutes	G	PTS system mannitol-specific	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
WZS3_k127_2678099_3	545243.BAEV01000067_gene2624	0.0001764	46.0	COG2893@1|root,COG2893@2|Bacteria,1V7TP@1239|Firmicutes,25C62@186801|Clostridia,36WQ4@31979|Clostridiaceae	186801|Clostridia	G	PTS system fructose IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
WZS3_k127_2678099_2	1139219.I569_01844	5.31e-38	147.0	COG3444@1|root,COG3444@2|Bacteria,1V46G@1239|Firmicutes,4HHP4@91061|Bacilli,4B28P@81852|Enterococcaceae	91061|Bacilli	G	PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
WZS3_k127_2678099_1	720555.BATR1942_17255	2.547e-63	241.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli,1ZQ0I@1386|Bacillus	91061|Bacilli	GKT	Mga helix-turn-helix domain	licR	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
WZS3_k127_2678099_0	545243.BAEV01000137_gene34	1.392e-127	420.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
WZS3_k127_2688668_1	1499683.CCFF01000014_gene4005	7.04e-97	320.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,25E61@186801|Clostridia,36UK0@31979|Clostridiaceae	186801|Clostridia	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	-	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS3_k127_2688668_2	941824.TCEL_01712	5.839e-96	317.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,247ZM@186801|Clostridia,36GAR@31979|Clostridiaceae	186801|Clostridia	I	3-oxoacid CoA-transferase, B subunit	ctfB1	-	2.8.3.5,2.8.3.8,2.8.3.9	ko:K01029,ko:K01035	ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS3_k127_2688668_3	509191.AEDB02000108_gene1616	2.063e-45	172.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,24GK6@186801|Clostridia	186801|Clostridia	F	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2,NUDIX,Nudix_N
WZS3_k127_2688668_0	293826.Amet_4248	6.778e-123	403.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
WZS3_k127_2688767_1	1304284.L21TH_1603	3.266e-64	228.0	COG2206@1|root,COG3437@1|root,COG3850@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,COG3850@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia,36USS@31979|Clostridiaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
WZS3_k127_2688767_0	1408823.AXUS01000045_gene1184	5.359e-105	347.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,25QF4@186804|Peptostreptococcaceae	186801|Clostridia	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WZS3_k127_2690610_0	1408823.AXUS01000022_gene2389	2.24e-260	820.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,25QTB@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WZS3_k127_2690610_5	649639.Bcell_1526	2.462e-27	113.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli,1ZHU7@1386|Bacillus	91061|Bacilli	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
WZS3_k127_2690610_2	1128398.Curi_c13380	1.156e-115	380.0	COG0667@1|root,COG1148@1|root,COG0667@2|Bacteria,COG1148@2|Bacteria,1UHXA@1239|Firmicutes,25E68@186801|Clostridia,26897@186813|unclassified Clostridiales	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4
WZS3_k127_2690610_4	1292035.H476_1715	2.068e-44	166.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,25RGT@186804|Peptostreptococcaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WZS3_k127_2690610_6	858215.Thexy_1144	3.441e-10	64.0	COG3906@1|root,COG3906@2|Bacteria,1VF5Z@1239|Firmicutes,24RAZ@186801|Clostridia,42H3M@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0473 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
WZS3_k127_2690610_3	350688.Clos_1661	7.01e-56	198.0	COG0735@1|root,COG0735@2|Bacteria,1V7F0@1239|Firmicutes,24JQE@186801|Clostridia,36I3W@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WZS3_k127_2690610_1	1304284.L21TH_1990	3.925e-231	735.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,36DE5@31979|Clostridiaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WZS3_k127_2694837_1	1499689.CCNN01000007_gene2200	1.051e-108	357.0	COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,25CE1@186801|Clostridia,36FKN@31979|Clostridiaceae	186801|Clostridia	E	Oligoendopeptidase, pepF M3 family	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
WZS3_k127_2694837_0	865861.AZSU01000006_gene1384	3.27e-179	579.0	COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,25CE1@186801|Clostridia,36FKN@31979|Clostridiaceae	186801|Clostridia	E	Oligoendopeptidase, pepF M3 family	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
WZS3_k127_2717915_0	1232443.BAIA02000071_gene559	1.47e-318	989.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,26828@186813|unclassified Clostridiales	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WZS3_k127_2717915_1	1408422.JHYF01000016_gene97	4.85e-66	228.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,36K17@31979|Clostridiaceae	186801|Clostridia	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
WZS3_k127_2733906_1	865861.AZSU01000001_gene212	1.505e-160	523.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,36DMH@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
WZS3_k127_2733906_2	350688.Clos_2252	2.032e-72	247.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,36IZJ@31979|Clostridiaceae	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00334,ko:K18330,ko:K22340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
WZS3_k127_2733906_3	1304284.L21TH_2537	5.991e-51	183.0	COG3411@1|root,COG3411@2|Bacteria,1V6DT@1239|Firmicutes,24M31@186801|Clostridia,36JIG@31979|Clostridiaceae	186801|Clostridia	C	Ferredoxin	-	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx
WZS3_k127_2733906_0	1121324.CLIT_13c01800	8.976e-283	880.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	hymB	-	1.12.1.3,1.17.1.11,1.6.5.3	ko:K00335,ko:K18331,ko:K22339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
WZS3_k127_2743085_3	1298865.H978DRAFT_1340	0.0001744	49.0	2EK66@1|root,33DWJ@2|Bacteria,1NJVK@1224|Proteobacteria,1SID7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2743085_0	293826.Amet_2638	1.857e-223	700.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,36UI3@31979|Clostridiaceae	186801|Clostridia	C	carboxyltransferase	pycB	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
WZS3_k127_2743085_1	1408823.AXUS01000033_gene2813	8.45e-45	166.0	COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,24I1I@186801|Clostridia,25R8I@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
WZS3_k127_2743085_2	580331.Thit_1676	9.533e-21	97.0	COG1237@1|root,COG1237@2|Bacteria,1UWI6@1239|Firmicutes,247K3@186801|Clostridia,42FV7@68295|Thermoanaerobacterales	186801|Clostridia	S	beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WZS3_k127_2747234_1	941824.TCEL_02096	7.923e-85	283.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,36DIE@31979|Clostridiaceae	186801|Clostridia	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
WZS3_k127_2747234_0	469618.FVAG_01473	5.267e-160	511.0	COG1129@1|root,COG1129@2|Bacteria,37997@32066|Fusobacteria	32066|Fusobacteria	G	Part of the ABC transporter complex MglABC involved in galactose methyl galactoside import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
WZS3_k127_2747468_2	1511.CLOST_1474	1.213e-22	99.0	COG4231@1|root,COG4231@2|Bacteria,1UHX9@1239|Firmicutes,24UZM@186801|Clostridia	186801|Clostridia	C	Best Blastp hit gi 7431974 pir F72256 'Fe-hydrogenase, subunit beta - Thermotoga maritima (strain MSB8)' gi 2865516 gb AAC02685.1 (AF044577) Fe-hydrogenase beta subunit Thermotoga maritima gi 4981989 gb AAD36495.1 AE001794_11 '(AE001794) Fe-hydrogenase, subunit beta Thermotoga maritima ', score	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
WZS3_k127_2747468_0	350688.Clos_1571	5.283e-165	526.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,36GS6@31979|Clostridiaceae	186801|Clostridia	C	Pyruvate:ferredoxin oxidoreductase core domain II	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WZS3_k127_2747468_1	350688.Clos_1570	4.842e-132	424.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,36WSB@31979|Clostridiaceae	186801|Clostridia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WZS3_k127_2754819_1	1121289.JHVL01000002_gene2353	9.827e-91	310.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,36FBU@31979|Clostridiaceae	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
WZS3_k127_2754819_0	272563.CD630_24600	5.737e-123	405.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25QX8@186804|Peptostreptococcaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WZS3_k127_2754819_2	931626.Awo_c26630	2.72e-05	48.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,25VH9@186806|Eubacteriaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WZS3_k127_2764852_0	666686.B1NLA3E_21085	5.71e-86	298.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,4HAQM@91061|Bacilli,1ZBDR@1386|Bacillus	91061|Bacilli	U	COG4962 Flp pilus assembly protein, ATPase CpaF	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WZS3_k127_2764852_4	1449063.JMLS01000030_gene428	6.517e-06	56.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,4HERS@91061|Bacilli,26QW8@186822|Paenibacillaceae	91061|Bacilli	U	pilus assembly protein TadB	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
WZS3_k127_2764852_3	509191.AEDB02000065_gene715	3.064e-09	60.0	2BCE2@1|root,325ZH@2|Bacteria,1URZ3@1239|Firmicutes,259X0@186801|Clostridia,3WQUP@541000|Ruminococcaceae	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
WZS3_k127_2764852_2	697303.Thewi_1941	1.03e-09	69.0	COG1716@1|root,COG1716@2|Bacteria,1VF0E@1239|Firmicutes,24P12@186801|Clostridia,42GKE@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM Forkhead-associated	-	-	-	-	-	-	-	-	-	-	-	-	FHA
WZS3_k127_2764852_1	350688.Clos_1353	5.778e-72	246.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,36HYM@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WZS3_k127_2765311_3	1209989.TepiRe1_1088	6.315e-53	189.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
WZS3_k127_2765311_6	864565.HMPREF0379_1874	1.087e-14	87.0	COG3103@1|root,COG3103@2|Bacteria,1VE1P@1239|Firmicutes,25GV6@186801|Clostridia	186801|Clostridia	T	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
WZS3_k127_2765311_2	645991.Sgly_1501	4.781e-57	217.0	COG2247@1|root,COG2247@2|Bacteria,1V7X5@1239|Firmicutes,24CP5@186801|Clostridia,264Q3@186807|Peptococcaceae	186801|Clostridia	M	cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Peptidase_M15_4,SLH
WZS3_k127_2765311_4	1408422.JHYF01000008_gene3629	1.409e-49	179.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,36JXK@31979|Clostridiaceae	186801|Clostridia	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WZS3_k127_2765311_5	1031288.AXAA01000004_gene1833	2.632e-29	136.0	COG2234@1|root,COG2234@2|Bacteria,1V3CU@1239|Firmicutes,25BEB@186801|Clostridia,36WEQ@31979|Clostridiaceae	186801|Clostridia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
WZS3_k127_2765311_0	1294142.CINTURNW_4553	3.834e-101	357.0	COG1173@1|root,COG1173@2|Bacteria,1V21B@1239|Firmicutes,2498X@186801|Clostridia,36GUS@31979|Clostridiaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,Peptidase_M28
WZS3_k127_2765311_1	1294142.CINTURNW_4554	3.859e-74	258.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS3_k127_2766874_0	1033810.HLPCO_001408	2.224e-97	326.0	COG1190@1|root,COG1190@2|Bacteria,2NNMH@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
WZS3_k127_2766874_1	1121938.AUDY01000009_gene2200	1.076e-40	155.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,3NED6@45667|Halobacillus	91061|Bacilli	G	Glycosyl hydrolase family 36 N-terminal domain	aga	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
WZS3_k127_2784111_1	1408422.JHYF01000009_gene1963	1.677e-157	509.0	COG0534@1|root,COG0534@2|Bacteria,1UZDQ@1239|Firmicutes,24F5D@186801|Clostridia,36VMW@31979|Clostridiaceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_2784111_0	1230342.CTM_19694	1.28e-241	754.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,36FKP@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0371 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
WZS3_k127_280342_0	318464.IO99_08090	1.566e-184	582.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,36DRC@31979|Clostridiaceae	186801|Clostridia	C	FAD linked oxidase domain protein	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
WZS3_k127_280342_4	1280663.ATVR01000020_gene2865	8.042e-23	102.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,4BZDQ@830|Butyrivibrio	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
WZS3_k127_280342_2	1280692.AUJL01000001_gene182	5.168e-123	402.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,36F3X@31979|Clostridiaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WZS3_k127_280342_1	1280692.AUJL01000001_gene183	5.326e-139	462.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,36H7Z@31979|Clostridiaceae	186801|Clostridia	S	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
WZS3_k127_280342_3	318464.IO99_08115	1.519e-35	144.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24SE7@186801|Clostridia	186801|Clostridia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_2819113_1	1301100.HG529303_gene3120	6.545e-71	247.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,36ES8@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WZS3_k127_2819113_0	1408422.JHYF01000014_gene257	3.23e-109	366.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,36DRG@31979|Clostridiaceae	186801|Clostridia	E	amidohydrolase	cpsA	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_2819113_2	1321778.HMPREF1982_01977	2.553e-67	254.0	COG0457@1|root,COG2199@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,26B8I@186813|unclassified Clostridiales	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,TPR_12,TPR_8
WZS3_k127_2819113_4	445335.CBN_3661	3.888e-29	119.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,36N04@31979|Clostridiaceae	186801|Clostridia	K	Iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	NikR_C
WZS3_k127_2819113_3	1033737.CAEV01000092_gene1934	5.677e-32	129.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,36F0H@31979|Clostridiaceae	186801|Clostridia	C	biosynthesis protein ThiH	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
WZS3_k127_2827023_0	1408422.JHYF01000013_gene593	1.916e-143	464.0	COG1232@1|root,COG1232@2|Bacteria,1U3HD@1239|Firmicutes,24DC6@186801|Clostridia,36H0W@31979|Clostridiaceae	186801|Clostridia	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
WZS3_k127_2827023_1	37659.JNLN01000001_gene2163	3.199e-96	317.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,36E69@31979|Clostridiaceae	186801|Clostridia	KO	Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
WZS3_k127_2832560_1	457570.Nther_1555	3.222e-53	190.0	COG3818@1|root,COG3818@2|Bacteria,1VATT@1239|Firmicutes,24Q5J@186801|Clostridia	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K06977	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,Acetyltransf_10
WZS3_k127_2832560_0	1410668.JNKC01000016_gene983	1.194e-64	226.0	COG1670@1|root,COG1670@2|Bacteria,1V6ZA@1239|Firmicutes,24IGT@186801|Clostridia,36VNH@31979|Clostridiaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WZS3_k127_2832560_3	621372.ACIH01000195_gene2559	7.562e-43	161.0	COG1335@1|root,COG1335@2|Bacteria,1V7B8@1239|Firmicutes,4HJEA@91061|Bacilli,26WTP@186822|Paenibacillaceae	91061|Bacilli	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
WZS3_k127_2832560_2	1121090.KB894715_gene2698	2.854e-45	168.0	COG0454@1|root,COG0456@2|Bacteria,1VFTU@1239|Firmicutes,4HQGT@91061|Bacilli	91061|Bacilli	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_2832560_4	1211817.CCAT010000046_gene2635	1.109e-18	90.0	COG2421@1|root,COG2421@2|Bacteria,1TQ67@1239|Firmicutes,24AKC@186801|Clostridia,36IMH@31979|Clostridiaceae	186801|Clostridia	C	Acetamidase/Formamidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	FmdA_AmdA
WZS3_k127_284786_2	68170.KL590470_gene11116	4.183e-22	97.0	COG3794@1|root,COG3794@2|Bacteria,2IQAI@201174|Actinobacteria,4E5B1@85010|Pseudonocardiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
WZS3_k127_284786_0	696281.Desru_1649	2.623e-117	383.0	COG1657@1|root,COG1657@2|Bacteria,1TPY3@1239|Firmicutes,247MQ@186801|Clostridia,2617M@186807|Peptococcaceae	186801|Clostridia	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_284786_1	1123009.AUID01000035_gene1226	6.01e-107	350.0	COG1741@1|root,COG1741@2|Bacteria,1TQDV@1239|Firmicutes,2497R@186801|Clostridia,269T8@186813|unclassified Clostridiales	186801|Clostridia	S	Pirin C-terminal cupin domain	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WZS3_k127_2856737_1	1121289.JHVL01000040_gene3171	5.518e-95	323.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,36F9B@31979|Clostridiaceae	186801|Clostridia	S	Glycosyl hydrolases family 18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
WZS3_k127_2856737_0	1286171.EAL2_c16170	1.166e-157	515.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,25UTR@186806|Eubacteriaceae	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
WZS3_k127_2864172_0	610130.Closa_2760	3.03e-111	372.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,223RM@1506553|Lachnoclostridium	186801|Clostridia	T	Diguanylate cyclase and metal dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_3,PAS_4,PAS_9
WZS3_k127_2864172_1	562743.JH976440_gene233	4.662e-44	166.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran_2
WZS3_k127_2884152_0	1511.CLOST_0831	6.752e-111	368.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25T7D@186804|Peptostreptococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WZS3_k127_2884152_2	1321778.HMPREF1982_00802	4.013e-81	281.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia	186801|Clostridia	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
WZS3_k127_2884152_4	555079.Toce_0455	3.811e-31	129.0	COG1846@1|root,COG1846@2|Bacteria,1V9AQ@1239|Firmicutes,24GW2@186801|Clostridia	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WZS3_k127_2884152_1	994573.T472_0207645	7.555e-87	291.0	COG1309@1|root,COG1309@2|Bacteria,1VCMC@1239|Firmicutes,24ND2@186801|Clostridia,36MGW@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_2884152_3	272558.10176554	1.593e-50	190.0	COG0454@1|root,COG0456@2|Bacteria,1UXXB@1239|Firmicutes,4HEEJ@91061|Bacilli,1ZS91@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
WZS3_k127_2884152_5	138119.DSY0997	7.657e-28	126.0	COG3180@1|root,COG3180@2|Bacteria,1V600@1239|Firmicutes,24GPC@186801|Clostridia,266A1@186807|Peptococcaceae	186801|Clostridia	S	ammonia monooxygenase	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
WZS3_k127_2884152_6	1278304.JAFR01000007_gene93	2.207e-21	96.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	1.1.1.34,2.7.1.89	ko:K00021,ko:K07251	ko00730,ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00730,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082,R02134	RC00002,RC00004,RC00017,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Choline_kinase
WZS3_k127_2901554_2	1423814.HMPREF0549_1102	6.874e-11	63.0	COG4892@1|root,COG4892@2|Bacteria,1V64Y@1239|Firmicutes,4HNUM@91061|Bacilli,3F812@33958|Lactobacillaceae	91061|Bacilli	S	Cytochrome B5	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
WZS3_k127_2901554_3	1460634.JCM19037_1267	1.096e-05	50.0	COG4892@1|root,COG4892@2|Bacteria,1VEGK@1239|Firmicutes,4IRZ3@91061|Bacilli	91061|Bacilli	S	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
WZS3_k127_2901554_0	931626.Awo_c05860	4.211e-167	540.0	COG2199@1|root,COG2206@1|root,COG3437@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes	1239|Firmicutes	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,HisKA_7TM,PAS,PAS_3,PAS_8,Response_reg
WZS3_k127_2901554_1	931626.Awo_c05850	2.295e-45	168.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG2972@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2972@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,25ZV3@186806|Eubacteriaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,Hpt,Response_reg
WZS3_k127_2920339_1	318464.IO99_18200	9.147e-31	124.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,36FPD@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,SRP54
WZS3_k127_2920339_0	485916.Dtox_0536	1.732e-62	221.0	COG1309@1|root,COG1309@2|Bacteria,1V3XC@1239|Firmicutes,24JC2@186801|Clostridia,2663F@186807|Peptococcaceae	186801|Clostridia	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_2920339_2	192952.MM_3157	1.759e-23	107.0	COG1680@1|root,arCOG00771@2157|Archaea	2157|Archaea	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A1202	Beta-lactamase
WZS3_k127_2950517_3	1526927.Plano_0143	2.618e-14	78.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H9VG@91061|Bacilli,26EJB@186818|Planococcaceae	91061|Bacilli	N	SRP54-type protein, GTPase domain	flhF	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
WZS3_k127_2950517_0	293826.Amet_0615	6.872e-203	642.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,36EDM@31979|Clostridiaceae	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
WZS3_k127_2950517_2	1121289.JHVL01000003_gene2208	7.746e-59	208.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,36EDM@31979|Clostridiaceae	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
WZS3_k127_2950517_1	1304284.L21TH_2252	1.288e-92	314.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia,36DIJ@31979|Clostridiaceae	186801|Clostridia	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
WZS3_k127_2958940_2	743719.PaelaDRAFT_0595	1.353e-114	377.0	COG4188@1|root,COG4188@2|Bacteria,1UZMD@1239|Firmicutes,4HEFX@91061|Bacilli,26SNS@186822|Paenibacillaceae	91061|Bacilli	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
WZS3_k127_2958940_3	1449050.JNLE01000003_gene2137	5.709e-51	188.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	csaA	-	-	ko:K06878	-	-	-	-	ko00000	-	-	-	DUF1905,OmdA,tRNA_bind
WZS3_k127_2958940_0	379066.GAU_2742	1.199e-261	829.0	COG0433@1|root,COG0433@2|Bacteria,1ZUJE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
WZS3_k127_2958940_1	398512.JQKC01000011_gene323	2.169e-210	660.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WGNF@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
WZS3_k127_2958940_5	398512.JQKC01000011_gene325	7.337e-19	87.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,HTS
WZS3_k127_2979723_3	189425.PGRAT_11010	7.253e-51	186.0	COG0716@1|root,COG0716@2|Bacteria,1TYNY@1239|Firmicutes,4I7TI@91061|Bacilli,26XF6@186822|Paenibacillaceae	91061|Bacilli	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2979723_1	645991.Sgly_1152	8.368e-83	280.0	COG1309@1|root,COG1309@2|Bacteria,1V9XJ@1239|Firmicutes,24I61@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
WZS3_k127_2979723_0	1121335.Clst_2249	4.222e-116	397.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
WZS3_k127_2979723_2	633697.EubceDRAFT1_1876	1.343e-52	188.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,25X2Z@186806|Eubacteriaceae	186801|Clostridia	T	response regulator	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
WZS3_k127_3002213_2	1499683.CCFF01000016_gene616	6.171e-55	194.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,36EIX@31979|Clostridiaceae	186801|Clostridia	G	Aldolase	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
WZS3_k127_3002213_0	986075.CathTA2_0846	3.735e-110	370.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli	91061|Bacilli	J	NOL1 NOP2 sun family protein	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
WZS3_k127_3002213_1	1444310.JANV01000099_gene1885	8.975e-84	285.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli,1ZCAM@1386|Bacillus	91061|Bacilli	J	Belongs to the pseudouridine synthase RsuA family	rsuA	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_3002213_3	1282887.AUJG01000007_gene2367	8.72e-05	50.0	COG1559@1|root,COG1559@2|Bacteria,1TX6E@1239|Firmicutes,24W6Z@186801|Clostridia	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	-	-	-	-	-	-	-	-	-	-	-	-	YceG
WZS3_k127_3005234_1	1321778.HMPREF1982_02242	1.277e-59	211.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,268KS@186813|unclassified Clostridiales	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WZS3_k127_3005234_2	1121289.JHVL01000004_gene2121	3.266e-52	194.0	COG3601@1|root,COG3601@2|Bacteria,1UJPR@1239|Firmicutes,25F7W@186801|Clostridia,36FP7@31979|Clostridiaceae	186801|Clostridia	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS,ECF_trnsprt
WZS3_k127_3005234_0	293826.Amet_3767	4.94e-127	408.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,36DG9@31979|Clostridiaceae	186801|Clostridia	E	oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WZS3_k127_3026969_1	688269.Theth_0220	3.071e-61	224.0	COG2931@1|root,COG2931@2|Bacteria,2GE36@200918|Thermotogae	200918|Thermotogae	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3026969_0	1408422.JHYF01000004_gene1671	3.82e-152	500.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	ygeV	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_8,PAS_9,Sigma54_activat,SpoVT_C
WZS3_k127_3026969_2	931626.Awo_c20260	2.269e-11	66.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,25YRR@186806|Eubacteriaceae	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
WZS3_k127_3040268_3	1347392.CCEZ01000049_gene1318	1.749e-17	86.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia,36MWG@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
WZS3_k127_3040268_1	1121324.CLIT_10c01800	7.52e-87	292.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
WZS3_k127_3040268_2	1391646.AVSU01000037_gene2058	6.547e-60	214.0	COG1309@1|root,COG1309@2|Bacteria,1VG3M@1239|Firmicutes,25BA9@186801|Clostridia,25UAR@186804|Peptostreptococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
WZS3_k127_3040268_0	189426.PODO_07945	6.676e-110	358.0	28H6R@1|root,2Z7J3@2|Bacteria,1TQ2I@1239|Firmicutes,4HCYQ@91061|Bacilli,26UIN@186822|Paenibacillaceae	91061|Bacilli	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3133740_2	1304284.L21TH_0923	1.343e-98	326.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,36DXB@31979|Clostridiaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA1	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WZS3_k127_3133740_0	1294142.CINTURNW_0084	3.083e-117	384.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,36F0E@31979|Clostridiaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WZS3_k127_3133740_1	1321778.HMPREF1982_00332	1.304e-103	343.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,268B8@186813|unclassified Clostridiales	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16783,ko:K16785	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
WZS3_k127_3133740_3	1286171.EAL2_c01910	3.73e-68	239.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,25US1@186806|Eubacteriaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WZS3_k127_3133740_4	1347392.CCEZ01000013_gene2656	2.511e-61	214.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,36HZ3@31979|Clostridiaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WZS3_k127_3133740_5	1511.CLOST_2161	2.564e-56	199.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,25RE4@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WZS3_k127_3136899_3	1286171.EAL2_808p00650	1.353e-64	229.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,25VHG@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
WZS3_k127_3136899_6	1449126.JQKL01000034_gene1288	9.893e-06	50.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,268D3@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
WZS3_k127_3136899_0	1443125.Z962_04575	1.83e-155	500.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,36F6N@31979|Clostridiaceae	186801|Clostridia	E	PFAM aminotransferase class I and II	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS3_k127_3136899_4	903814.ELI_1691	3.256e-62	234.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,25WC3@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K18940	ko02020,map02020	M00716,M00717	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_3136899_2	913865.DOT_0403	3.278e-70	244.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,2616J@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	ko:K02483,ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_3136899_1	1410668.JNKC01000008_gene2729	3.21e-77	265.0	COG4720@1|root,COG4720@2|Bacteria,1VF2R@1239|Firmicutes,24QR3@186801|Clostridia,36G1D@31979|Clostridiaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
WZS3_k127_3136899_5	1410668.JNKC01000008_gene2730	3.747e-58	209.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,36EK3@31979|Clostridiaceae	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
WZS3_k127_321165_3	469617.FUAG_02053	2.561e-69	246.0	COG0561@1|root,COG0561@2|Bacteria,3799Q@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_321165_2	1294142.CINTURNW_3143	3.419e-80	279.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,36DGK@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
WZS3_k127_321165_0	332101.JIBU02000012_gene924	1.027e-116	389.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,36E1H@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
WZS3_k127_321165_1	1064535.MELS_0280	3.581e-106	355.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4H375@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
WZS3_k127_321165_4	1120998.AUFC01000001_gene1772	1.885e-42	165.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WCM7@538999|Clostridiales incertae sedis	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14365	CM_2,SKI,Shikimate_DH,Shikimate_dh_N
WZS3_k127_323688_1	1304284.L21TH_0593	2.911e-31	128.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia,36HA3@31979|Clostridiaceae	186801|Clostridia	C	ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
WZS3_k127_323688_0	1304284.L21TH_0592	6.816e-155	511.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,36EI6@31979|Clostridiaceae	186801|Clostridia	U	Belongs to the V-ATPase 116 kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
WZS3_k127_323688_2	1511.CLOST_2319	6.486e-30	124.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,25RSX@186804|Peptostreptococcaceae	186801|Clostridia	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
WZS3_k127_3284222_1	584708.Apau_2294	1.272e-70	240.0	COG0618@1|root,COG0618@2|Bacteria,3TBXW@508458|Synergistetes	508458|Synergistetes	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3284222_2	584708.Apau_2294	2.948e-54	192.0	COG0618@1|root,COG0618@2|Bacteria,3TBXW@508458|Synergistetes	508458|Synergistetes	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3284222_0	931626.Awo_c28740	1.985e-111	373.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,25V43@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WZS3_k127_3284222_3	265729.GS18_0207195	4.936e-39	150.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,4IR2I@91061|Bacilli,1ZRQZ@1386|Bacillus	91061|Bacilli	S	WLM domain	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WZS3_k127_3285072_1	37659.JNLN01000001_gene1530	9.329e-36	143.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,36IAW@31979|Clostridiaceae	186801|Clostridia	K	GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
WZS3_k127_3285072_0	865861.AZSU01000002_gene2377	2.332e-169	541.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,36EK3@31979|Clostridiaceae	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
WZS3_k127_3285072_2	743719.PaelaDRAFT_5018	2.309e-21	99.0	COG1051@1|root,COG1051@2|Bacteria,1V4ND@1239|Firmicutes,4HJ5H@91061|Bacilli,26YW0@186822|Paenibacillaceae	91061|Bacilli	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS3_k127_3285072_3	1408303.JNJJ01000008_gene349	1.365e-11	75.0	COG1879@1|root,COG1879@2|Bacteria,1TQZS@1239|Firmicutes,4HCUS@91061|Bacilli,1ZB0G@1386|Bacillus	91061|Bacilli	G	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
WZS3_k127_3285072_4	1408321.JNJD01000007_gene125	2.14e-09	66.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,27IFD@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
WZS3_k127_330090_0	370438.PTH_0541	2.477e-11	70.0	COG0782@1|root,COG0782@2|Bacteria,1VCI7@1239|Firmicutes,24P10@186801|Clostridia,262T8@186807|Peptococcaceae	186801|Clostridia	J	transcription elongation factor, GreA GreB	-	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB
WZS3_k127_330090_1	621372.ACIH01000057_gene1189	3.661e-07	61.0	COG1470@1|root,COG1470@2|Bacteria,1VMQY@1239|Firmicutes,4HSBN@91061|Bacilli,277E2@186822|Paenibacillaceae	91061|Bacilli	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3307843_2	1408422.JHYF01000009_gene2004	1.802e-54	194.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,36DGN@31979|Clostridiaceae	186801|Clostridia	P	Potassium uptake protein	ktrC	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WZS3_k127_3307843_1	596329.HMPREF0631_1453	9.884e-59	213.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,25RAX@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WZS3_k127_3307843_0	1391646.AVSU01000001_gene276	2.006e-153	492.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,25R7N@186804|Peptostreptococcaceae	186801|Clostridia	J	Phenylalanyl-tRNA synthetase alpha subunit	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
WZS3_k127_3307843_3	1033744.CAEL01000016_gene248	8.058e-25	106.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,22GKJ@1570339|Peptoniphilaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
WZS3_k127_3365490_0	1410668.JNKC01000007_gene796	1.473e-180	582.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,36EYT@31979|Clostridiaceae	186801|Clostridia	G	Glycosyltransferase 36 associated	ndvB	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glyco_hydro_36,Glyco_transf_36,Glycoamylase
WZS3_k127_3375105_2	1304284.L21TH_1157	4.468e-40	152.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,36GJ7@31979|Clostridiaceae	186801|Clostridia	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_3375105_3	649747.HMPREF0083_04126	1.778e-34	136.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,4HJ3J@91061|Bacilli,2751S@186822|Paenibacillaceae	91061|Bacilli	S	Metal-sensitive transcriptional repressor	csoR_2	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WZS3_k127_3375105_0	1469948.JPNB01000001_gene1226	1.393e-307	963.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,36DJE@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_3375105_1	350688.Clos_1677	5.363e-56	203.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1V56Q@1239|Firmicutes,25EWJ@186801|Clostridia,36USQ@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WZS3_k127_3380167_4	537007.BLAHAN_04733	9.133e-14	72.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3XYIF@572511|Blautia	186801|Clostridia	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WZS3_k127_3380167_3	702450.CUW_2488	1.313e-56	200.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,3VQGS@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	-	-	-	-	-	-	-	-	-	-	FabA
WZS3_k127_3380167_0	272562.CA_C3573	7.277e-165	529.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,36E5Q@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WZS3_k127_3380167_1	1321778.HMPREF1982_02572	6.849e-94	313.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,26846@186813|unclassified Clostridiales	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS3_k127_3380167_2	37659.JNLN01000001_gene2154	3.235e-91	308.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,36FFG@31979|Clostridiaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WZS3_k127_3385894_3	653733.Selin_0942	6.624e-30	122.0	COG2199@1|root,COG4753@1|root,COG3706@2|Bacteria,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	GGDEF,Guanylate_cyc,HATPase_c,HisKA,Pkinase,Response_reg,SpoIIE
WZS3_k127_3385894_1	572544.Ilyop_0320	3.202e-144	483.0	COG4191@1|root,COG4191@2|Bacteria,37ARF@32066|Fusobacteria	32066|Fusobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg,SBP_bac_3,dCache_1
WZS3_k127_3385894_0	572544.Ilyop_0292	1.217e-236	740.0	COG3333@1|root,COG3333@2|Bacteria,3789P@32066|Fusobacteria	32066|Fusobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
WZS3_k127_3385894_4	1348635.BBJY01000004_gene3070	1.356e-23	106.0	2E96H@1|root,333F3@2|Bacteria,1PIDZ@1224|Proteobacteria,1TI39@1236|Gammaproteobacteria,1XY9Z@135623|Vibrionales	135623|Vibrionales	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
WZS3_k127_3385894_2	572544.Ilyop_0290	4.857e-135	437.0	COG3181@1|root,COG3181@2|Bacteria,379J4@32066|Fusobacteria	32066|Fusobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
WZS3_k127_3385894_5	760154.Sulba_0619	5.063e-15	81.0	COG1767@1|root,COG3697@1|root,COG1767@2|Bacteria,COG3697@2|Bacteria,1N9IK@1224|Proteobacteria,431YF@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase	citG	GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046917,GO:0051186,GO:0051188,GO:0051189,GO:0051191,GO:0071704,GO:1901564,GO:1901576	2.4.2.52,2.7.7.61	ko:K05966,ko:K13927,ko:K13930	ko02020,map02020	-	R09675,R10706	RC00049,RC00063	ko00000,ko00001,ko01000	-	-	-	CitG,CitX
WZS3_k127_3389195_2	1304284.L21TH_0719	4.121e-107	356.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQ94@1239|Firmicutes,248BK@186801|Clostridia,36EBF@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
WZS3_k127_3389195_1	1347392.CCEZ01000043_gene217	9.047e-155	502.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36EY7@31979|Clostridiaceae	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
WZS3_k127_3389195_4	697281.Mahau_0937	1.208e-20	96.0	COG3086@1|root,COG3086@2|Bacteria,1VEYP@1239|Firmicutes,24R8Z@186801|Clostridia	186801|Clostridia	T	PFAM Positive regulator of sigma(E) RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
WZS3_k127_3389195_0	1128398.Curi_c17290	1.037e-263	824.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,267N5@186813|unclassified Clostridiales	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
WZS3_k127_3389195_3	203119.Cthe_1341	5.237e-91	308.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS3_k127_3397221_2	986075.CathTA2_0262	7.394e-36	138.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli	91061|Bacilli	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
WZS3_k127_3397221_0	195103.CPF_1277	1.154e-98	329.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,36ECT@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
WZS3_k127_3397221_1	1286171.EAL2_808p05380	7.167e-81	278.0	COG2230@1|root,COG2230@2|Bacteria,1UMJ8@1239|Firmicutes,25H4D@186801|Clostridia	186801|Clostridia	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
WZS3_k127_3406761_0	931626.Awo_c30520	1.796e-111	376.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,25UZ5@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
WZS3_k127_3406761_1	1304284.L21TH_1561	4.365e-43	166.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,36H10@31979|Clostridiaceae	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
WZS3_k127_341137_1	457570.Nther_1015	1.362e-114	375.0	COG0312@1|root,COG0312@2|Bacteria,1TSQC@1239|Firmicutes,248MD@186801|Clostridia	186801|Clostridia	S	Modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WZS3_k127_341137_0	1009370.ALO_13075	1.291e-159	516.0	COG0154@1|root,COG0154@2|Bacteria,1TRFI@1239|Firmicutes,4H6PR@909932|Negativicutes	909932|Negativicutes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
WZS3_k127_3421077_2	1526927.Plano_0106	0.0005067	45.0	2DR71@1|root,33AGR@2|Bacteria,1VKHI@1239|Firmicutes,4HRPI@91061|Bacilli	91061|Bacilli	S	Putative motility protein	-	-	-	-	-	-	-	-	-	-	-	-	YjfB_motility
WZS3_k127_3421077_0	649747.HMPREF0083_01938	1.034e-31	133.0	COG3861@1|root,COG3861@2|Bacteria,1V71H@1239|Firmicutes,4IRSD@91061|Bacilli,276WN@186822|Paenibacillaceae	91061|Bacilli	S	Heat induced stress protein YflT	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,YflT
WZS3_k127_3421077_1	1395571.TMS3_0108010	1.008e-18	87.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	yjbJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CsbD
WZS3_k127_3421581_1	1128398.Curi_c13070	6.816e-49	179.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,267RF@186813|unclassified Clostridiales	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WZS3_k127_3421581_0	1121289.JHVL01000030_gene420	1.315e-65	227.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,36HY1@31979|Clostridiaceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
WZS3_k127_3421581_2	411489.CLOL250_00250	7.753e-19	93.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,36I6A@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WZS3_k127_3425515_1	1408422.JHYF01000001_gene2918	1.767e-32	136.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia,36FSA@31979|Clostridiaceae	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
WZS3_k127_3425515_0	1286171.EAL2_c11550	1.902e-121	394.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,25VVP@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
WZS3_k127_3425515_2	1321778.HMPREF1982_04034	4.87e-24	103.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,269UT@186813|unclassified Clostridiales	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
WZS3_k127_3425515_3	1286171.EAL2_c11570	8.971e-22	99.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,25VRW@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WZS3_k127_3426317_2	457570.Nther_2811	5.803e-82	285.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia	186801|Clostridia	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
WZS3_k127_3426317_3	272562.CA_C1476	2.539e-78	266.0	COG1174@1|root,COG1174@2|Bacteria,1V24D@1239|Firmicutes,24H6D@186801|Clostridia,36GF5@31979|Clostridiaceae	186801|Clostridia	P	inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
WZS3_k127_3426317_1	272562.CA_C1475	1.1e-114	374.0	COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,248YZ@186801|Clostridia,36EGJ@31979|Clostridiaceae	186801|Clostridia	E	glycine, betaine	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
WZS3_k127_3426317_0	272562.CA_C1474	9.395e-136	438.0	COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,248A1@186801|Clostridia,36DBY@31979|Clostridiaceae	186801|Clostridia	P	glycine, betaine	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
WZS3_k127_3446325_0	702450.CUW_0359	3.788e-69	239.0	COG0494@1|root,COG0494@2|Bacteria,1UK6F@1239|Firmicutes,3VUXX@526524|Erysipelotrichia	526524|Erysipelotrichia	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS3_k127_3446325_1	1121289.JHVL01000037_gene3019	8.56e-61	216.0	COG1357@1|root,COG1357@2|Bacteria,1VAPB@1239|Firmicutes,24J9N@186801|Clostridia,36I04@31979|Clostridiaceae	186801|Clostridia	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
WZS3_k127_346249_1	1121930.AQXG01000016_gene1813	1.357e-51	188.0	COG0668@1|root,COG0668@2|Bacteria,4NFHD@976|Bacteroidetes,1IYJY@117747|Sphingobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
WZS3_k127_346249_0	1449343.JQLQ01000002_gene907	1.107e-146	476.0	COG2133@1|root,COG2133@2|Bacteria,1TR38@1239|Firmicutes,4HBME@91061|Bacilli,27GU9@186828|Carnobacteriaceae	91061|Bacilli	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH,PKD,ThuA
WZS3_k127_346249_2	293826.Amet_3108	8.315e-34	132.0	COG0599@1|root,COG0599@2|Bacteria,1VD58@1239|Firmicutes,24Q09@186801|Clostridia	186801|Clostridia	S	protein, gamma-carboxymuconolactone decarboxylase subunit like protein	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WZS3_k127_346249_3	1243664.CAVL020000047_gene2248	5.329e-27	112.0	COG4912@1|root,COG4912@2|Bacteria,1TSAW@1239|Firmicutes,4HABR@91061|Bacilli,1ZBJS@1386|Bacillus	91061|Bacilli	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WZS3_k127_3486526_4	97138.C820_00499	2.028e-111	372.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DIS@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
WZS3_k127_3486526_0	1511.CLOST_0611	2.687e-150	482.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia	186801|Clostridia	P	phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
WZS3_k127_3486526_2	1511.CLOST_0612	6.891e-133	430.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,25QCJ@186804|Peptostreptococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS3_k127_3486526_3	871963.Desdi_0990	1.033e-131	426.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,2611K@186807|Peptococcaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS3_k127_3486526_1	1511.CLOST_0614	4.685e-140	448.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,25QFV@186804|Peptostreptococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WZS3_k127_3496443_2	293826.Amet_0017	2.251e-37	144.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,36E6G@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
WZS3_k127_3496443_0	935948.KE386495_gene1576	1.568e-110	374.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,42ESA@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
WZS3_k127_3496443_1	1449126.JQKL01000015_gene2942	2.792e-93	313.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,26AT3@186813|unclassified Clostridiales	186801|Clostridia	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
WZS3_k127_3503110_1	1121324.CLIT_23c04370	3.921e-65	233.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,25QN9@186804|Peptostreptococcaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WZS3_k127_3503110_0	350688.Clos_1469	3.309e-98	330.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,36DQN@31979|Clostridiaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
WZS3_k127_3503110_2	931626.Awo_c21130	7.552e-10	59.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25WN4@186806|Eubacteriaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WZS3_k127_3523959_1	1196324.A374_00779	1.283e-123	400.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
WZS3_k127_3523959_2	1292035.H476_1984	5.706e-108	356.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,25QK5@186804|Peptostreptococcaceae	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_3523959_0	1292035.H476_1985	1.757e-175	558.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,25QPX@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
WZS3_k127_3523959_3	1195236.CTER_0745	1.193e-97	327.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS3_k127_3523959_4	926561.KB900617_gene1476	5.573e-29	119.0	COG2199@1|root,COG2199@2|Bacteria,1VAHW@1239|Firmicutes,24MYS@186801|Clostridia,3WBY7@53433|Halanaerobiales	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PAS_9,Peripla_BP_3,dCache_1
WZS3_k127_3532539_1	632245.CLP_4075	1.438e-29	120.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,36GNE@31979|Clostridiaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WZS3_k127_3532539_0	1408422.JHYF01000003_gene893	1.179e-264	826.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,36DJB@31979|Clostridiaceae	186801|Clostridia	C	iron hydrogenase, small subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
WZS3_k127_3599645_1	1415775.U729_2297	1.939e-105	349.0	COG0535@1|root,COG0535@2|Bacteria,1UPAB@1239|Firmicutes,24A1Q@186801|Clostridia,36FP0@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
WZS3_k127_3599645_0	649639.Bcell_1382	4.498e-259	806.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1TQAZ@1239|Firmicutes,4HCQW@91061|Bacilli,1ZB16@1386|Bacillus	91061|Bacilli	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	yhcX	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
WZS3_k127_3604136_3	511051.CSE_08440	5.436e-12	67.0	COG1555@1|root,COG1596@1|root,COG1555@2|Bacteria,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01991,ko:K02237	ko02026,map02026	M00429	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.18,3.A.11.1,3.A.11.2	-	-	HHH_3,Poly_export,SLBB
WZS3_k127_3604136_1	350688.Clos_1738	7.657e-117	384.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,36DGY@31979|Clostridiaceae	186801|Clostridia	E	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
WZS3_k127_3604136_0	941824.TCEL_02011	3.377e-131	434.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia,36DPP@31979|Clostridiaceae	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
WZS3_k127_3604136_2	1408823.AXUS01000003_gene527	1.03e-103	353.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,25QGF@186804|Peptostreptococcaceae	186801|Clostridia	J	Elongation factor SelB, winged helix	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
WZS3_k127_360959_2	445335.CBN_2738	1.434e-39	152.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,36J1Q@31979|Clostridiaceae	186801|Clostridia	S	DJ-1 family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WZS3_k127_360959_1	1511.CLOST_0862	8.594e-85	289.0	COG1305@1|root,COG1305@2|Bacteria,1TP7G@1239|Firmicutes,24BSB@186801|Clostridia,25T87@186804|Peptostreptococcaceae	186801|Clostridia	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WZS3_k127_360959_0	1511.CLOST_0861	5.068e-120	391.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,25SRY@186804|Peptostreptococcaceae	186801|Clostridia	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS3_k127_3630676_0	926692.AZYG01000051_gene1850	2.777e-61	215.0	COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,25E73@186801|Clostridia,3WBUT@53433|Halanaerobiales	186801|Clostridia	CP	ATPases associated with a variety of cellular activities	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
WZS3_k127_3630676_1	1292035.H476_2920	4.289e-23	112.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,25R83@186804|Peptostreptococcaceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
WZS3_k127_3633317_2	568816.Acin_1868	2.229e-27	121.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4H2QM@909932|Negativicutes	909932|Negativicutes	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WZS3_k127_3633317_1	1121289.JHVL01000008_gene1227	1.76e-82	291.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,36DM2@31979|Clostridiaceae	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
WZS3_k127_3633317_3	1230342.CTM_20149	6.187e-23	103.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,36K5Z@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WZS3_k127_3633317_0	1121289.JHVL01000008_gene1225	1.706e-99	338.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia,36UNX@31979|Clostridiaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_3633354_0	1511.CLOST_1597	1.056e-190	601.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,25QYB@186804|Peptostreptococcaceae	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
WZS3_k127_3633354_1	1220589.CD32_17560	5.855e-57	203.0	2DBFK@1|root,2Z8Z7@2|Bacteria,1TQKG@1239|Firmicutes,4HDJX@91061|Bacilli,3IXJ2@400634|Lysinibacillus	91061|Bacilli	S	Protein of unknown function (DUF3298)	rsiV	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
WZS3_k127_3649740_2	1280668.ATVT01000021_gene1714	1.084e-38	149.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,4BX95@830|Butyrivibrio	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_3649740_1	545243.BAEV01000111_gene2816	7.822e-60	225.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia,36DS3@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_3649740_0	2325.TKV_c04700	9.726e-76	274.0	COG4632@1|root,COG4632@2|Bacteria,1TQBV@1239|Firmicutes,24AWX@186801|Clostridia,42EYG@68295|Thermoanaerobacterales	186801|Clostridia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,Metallophos,NAGPA,Pur_ac_phosph_N,SLH
WZS3_k127_3661762_3	350688.Clos_2006	2.995e-54	199.0	COG2227@1|root,COG2227@2|Bacteria,1V218@1239|Firmicutes,25EUC@186801|Clostridia,36UUN@31979|Clostridiaceae	186801|Clostridia	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS3_k127_3661762_1	293826.Amet_1628	5.5e-84	288.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,36DPJ@31979|Clostridiaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
WZS3_k127_3661762_7	1121289.JHVL01000021_gene790	8.893e-35	141.0	28NR9@1|root,2ZBQJ@2|Bacteria,1UZEN@1239|Firmicutes,24G0V@186801|Clostridia,36I0Y@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3661762_4	1304284.L21TH_1019	9.329e-54	198.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,36DNU@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
WZS3_k127_3661762_0	1121324.CLIT_10c02640	2.22e-309	959.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25QSG@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WZS3_k127_3661762_5	195103.CPF_2146	1.863e-53	192.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,36I2Z@31979|Clostridiaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WZS3_k127_3661762_8	1121324.CLIT_10c02620	1.017e-22	98.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WZS3_k127_3661762_6	1354300.AUQY01000002_gene735	1.566e-47	172.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,22HHS@1570339|Peptoniphilaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WZS3_k127_3661762_2	1286171.EAL2_c10050	9.665e-81	275.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,25VDT@186806|Eubacteriaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
WZS3_k127_3661989_1	1321778.HMPREF1982_00032	1.503e-28	123.0	COG3758@1|root,COG3758@2|Bacteria,1VH52@1239|Firmicutes,24P8J@186801|Clostridia	186801|Clostridia	S	HutD	-	-	-	-	-	-	-	-	-	-	-	-	HutD
WZS3_k127_3661989_0	1321779.HMPREF1984_00211	1.224e-53	196.0	COG1011@1|root,COG1011@2|Bacteria,379ZB@32066|Fusobacteria	32066|Fusobacteria	S	Psort location Cytoplasmic, score	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
WZS3_k127_3664406_3	720554.Clocl_2720	2.807e-57	205.0	COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,3WIBC@541000|Ruminococcaceae	186801|Clostridia	C	ferredoxin oxidoreductase	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WZS3_k127_3664406_1	203119.Cthe_2797	1.279e-134	434.0	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,3WHQF@541000|Ruminococcaceae	186801|Clostridia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WZS3_k127_3664406_0	97138.C820_01170	3.534e-234	729.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,36DP4@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WZS3_k127_3664406_5	1410668.JNKC01000006_gene610	1.644e-18	86.0	2DEEB@1|root,2ZMM9@2|Bacteria,1W1QH@1239|Firmicutes,255W1@186801|Clostridia,36U3W@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3664406_2	1410668.JNKC01000006_gene609	6.77e-88	301.0	COG1511@1|root,COG1511@2|Bacteria,1UJCA@1239|Firmicutes,25F1R@186801|Clostridia,36G9R@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
WZS3_k127_3664406_4	994573.T472_0215620	1.618e-18	88.0	COG0842@1|root,COG0842@2|Bacteria,1UJSM@1239|Firmicutes,25F8Y@186801|Clostridia,36V7D@31979|Clostridiaceae	186801|Clostridia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS3_k127_3739644_2	1122921.KB898185_gene4183	1.76e-22	103.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,4HM44@91061|Bacilli,26UF3@186822|Paenibacillaceae	91061|Bacilli	S	metal-binding, possibly nucleic acid-binding protein	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
WZS3_k127_3739644_3	864565.HMPREF0379_0746	1.036e-15	78.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
WZS3_k127_3739644_0	1304284.L21TH_1395	1.796e-116	384.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,36E96@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
WZS3_k127_3739644_1	1340434.AXVA01000003_gene2339	1.487e-38	148.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus	91061|Bacilli	S	COG2270 Permeases of the major facilitator superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WZS3_k127_3750994_1	756499.Desde_1469	1.128e-67	232.0	COG1145@1|root,COG1145@2|Bacteria,1TQG5@1239|Firmicutes,248IV@186801|Clostridia,26038@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7
WZS3_k127_3750994_0	338969.Rfer_2355	1.058e-175	559.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,2WGKT@28216|Betaproteobacteria,4AJXR@80864|Comamonadaceae	28216|Betaproteobacteria	NT	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
WZS3_k127_3763438_0	1499689.CCNN01000007_gene927	1.511e-99	338.0	COG1193@1|root,COG1193@2|Bacteria,1TQWB@1239|Firmicutes,24A15@186801|Clostridia,36F5M@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS5	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V
WZS3_k127_3763438_1	1511.CLOST_1631	3.851e-80	271.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,25TWQ@186804|Peptostreptococcaceae	186801|Clostridia	V	Flavin reductase like domain	flr	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WZS3_k127_3763438_2	1121875.KB907547_gene2908	1.381e-34	149.0	COG0834@1|root,COG2172@1|root,COG2208@1|root,COG3829@1|root,COG0834@2|Bacteria,COG2172@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria,4PPGD@976|Bacteroidetes	976|Bacteroidetes	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3765119_3	1410668.JNKC01000001_gene1912	5.581e-26	110.0	COG1943@1|root,COG1943@2|Bacteria,1V553@1239|Firmicutes,2495R@186801|Clostridia,36F6G@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WZS3_k127_3765119_0	1541960.KQ78_00603	3.56e-71	247.0	COG1126@1|root,COG1126@2|Bacteria,3WV3K@544448|Tenericutes	544448|Tenericutes	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
WZS3_k127_3765119_1	1541960.KQ78_00604	2.934e-52	193.0	COG0765@1|root,COG0765@2|Bacteria	2|Bacteria	P	amino acid transport	glnM	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
WZS3_k127_3765119_2	1396141.BATP01000058_gene1998	1.09e-26	113.0	COG0834@1|root,COG0834@2|Bacteria,46TJR@74201|Verrucomicrobia,2IU6P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WZS3_k127_3785332_2	1301100.HG529378_gene4086	3.387e-34	134.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,36F4N@31979|Clostridiaceae	186801|Clostridia	P	Formate nitrite	fdhC	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
WZS3_k127_3785332_0	457396.CSBG_00890	8.15e-123	398.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,36F6F@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
WZS3_k127_3785332_1	1415775.U729_2964	1.131e-91	309.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,36EYP@31979|Clostridiaceae	186801|Clostridia	L	helicase	cshA2	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
WZS3_k127_3803720_1	1304284.L21TH_1199	1.867e-92	310.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,36DT5@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WZS3_k127_3803720_0	642492.Clole_2943	1.854e-265	847.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3372,PUD
WZS3_k127_3803720_2	1410668.JNKC01000001_gene1431	1.149e-48	175.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,36EGD@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS3_k127_3819185_2	933115.GPDM_06770	1.07e-19	92.0	COG2267@1|root,COG2267@2|Bacteria,1V5AW@1239|Firmicutes,4HHD9@91061|Bacilli,26GZR@186818|Planococcaceae	91061|Bacilli	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
WZS3_k127_3819185_0	511680.BUTYVIB_00305	5.172e-84	283.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,4BZWQ@830|Butyrivibrio	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
WZS3_k127_3819185_1	545243.BAEV01000047_gene3673	3.033e-70	242.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,36I54@31979|Clostridiaceae	186801|Clostridia	EH	Glutamine amidotransferase of anthranilate synthase	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17720	GATase
WZS3_k127_3835551_1	641107.CDLVIII_1934	1.997e-125	413.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,36DW1@31979|Clostridiaceae	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
WZS3_k127_3835551_3	350688.Clos_1682	1.614e-76	263.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia,36F3W@31979|Clostridiaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WZS3_k127_3835551_5	1121324.CLIT_10c04000	6.046e-52	196.0	arCOG05878@1|root,2ZC5B@2|Bacteria,1V210@1239|Firmicutes,24GVY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3835551_4	509191.AEDB02000094_gene4229	6.855e-56	200.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,3WIMV@541000|Ruminococcaceae	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.12.1.3,1.6.5.3	ko:K00334,ko:K18330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iHN637.CLJU_RS07215	2Fe-2S_thioredx
WZS3_k127_3835551_6	398512.JQKC01000002_gene1716	5.382e-43	160.0	COG3411@1|root,COG3411@2|Bacteria,1V6DT@1239|Firmicutes,24M31@186801|Clostridia	186801|Clostridia	C	Ferredoxin	-	-	1.12.1.3	ko:K17992	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx
WZS3_k127_3835551_0	857293.CAAU_2434	3.446e-280	871.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,36EMP@31979|Clostridiaceae	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
WZS3_k127_3835551_2	994573.T472_0219125	3.358e-102	335.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,36DJB@31979|Clostridiaceae	186801|Clostridia	C	iron hydrogenase, small subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iHN637.CLJU_RS07205	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,Fer4_9,NADH-G_4Fe-4S_3
WZS3_k127_3857976_2	572544.Ilyop_0300	4.448e-117	385.0	COG1883@1|root,COG1883@2|Bacteria,378FV@32066|Fusobacteria	32066|Fusobacteria	C	Psort location CytoplasmicMembrane, score 10.00	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
WZS3_k127_3857976_6	1120998.AUFC01000003_gene1414	1.227e-34	137.0	COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,25F1E@186801|Clostridia,3WDNN@538999|Clostridiales incertae sedis	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
WZS3_k127_3857976_7	1408422.JHYF01000006_gene1279	1.387e-14	79.0	COG3630@1|root,COG3630@2|Bacteria,1VKW0@1239|Firmicutes,24VA0@186801|Clostridia,36P5Y@31979|Clostridiaceae	186801|Clostridia	C	decarboxylase, gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	OAD_gamma
WZS3_k127_3857976_0	1408422.JHYF01000006_gene1278	7.024e-263	816.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,36E1X@31979|Clostridiaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	yqjD	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
WZS3_k127_3857976_4	1408422.JHYF01000006_gene1277	1.666e-63	220.0	COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,24HPI@186801|Clostridia,36J72@31979|Clostridiaceae	186801|Clostridia	E	Glyoxalase-like domain	mce	-	4.4.1.5,5.1.99.1	ko:K01759,ko:K05606	ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00620,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02530,R02765,R09979	RC00004,RC00740,RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
WZS3_k127_3857976_3	293826.Amet_4540	3.35e-114	374.0	COG1703@1|root,COG1703@2|Bacteria,1TQT4@1239|Firmicutes,24944@186801|Clostridia,36G13@31979|Clostridiaceae	186801|Clostridia	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
WZS3_k127_3857976_5	1292035.H476_1137	7.791e-62	215.0	COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,24HAR@186801|Clostridia,25TDJ@186804|Peptostreptococcaceae	186801|Clostridia	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WZS3_k127_3857976_1	350688.Clos_0436	2.487e-149	477.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,24BDK@186801|Clostridia,36H9W@31979|Clostridiaceae	186801|Clostridia	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847,ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
WZS3_k127_386400_2	1541960.KQ78_01705	6.379e-35	136.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1400,PAF-AH_p_II
WZS3_k127_386400_1	545243.BAEV01000005_gene964	5.104e-83	285.0	28ITW@1|root,2Z8SQ@2|Bacteria,1TSYI@1239|Firmicutes,24CX0@186801|Clostridia,36IV0@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_386400_0	1123009.AUID01000021_gene1290	1.164e-247	793.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,2688X@186813|unclassified Clostridiales	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,EAL,GGDEF,HAMP,PAS_3,dCache_1,sCache_3_2
WZS3_k127_388655_0	1121428.DESHY_110402___1	6.052e-92	310.0	COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,24CUE@186801|Clostridia,264ZR@186807|Peptococcaceae	186801|Clostridia	E	PFAM L-asparaginase II	-	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
WZS3_k127_388655_1	1122915.AUGY01000070_gene4244	3.224e-27	119.0	2DBV7@1|root,2ZB9P@2|Bacteria,1UBN2@1239|Firmicutes,4HEYF@91061|Bacilli,26VBW@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
WZS3_k127_3906259_5	903814.ELI_3457	2.045e-08	55.0	COG1192@1|root,COG1192@2|Bacteria,1UI32@1239|Firmicutes,25EC1@186801|Clostridia	186801|Clostridia	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
WZS3_k127_3906259_1	1304284.L21TH_2281	5.791e-174	551.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,36EGP@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the acetokinase family	buk	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
WZS3_k127_3906259_3	445973.CLOBAR_01190	3.349e-107	355.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,25RBP@186804|Peptostreptococcaceae	186801|Clostridia	C	phosphate butyryltransferase	ptb	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
WZS3_k127_3906259_2	293826.Amet_4310	8.48e-153	490.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,36EWW@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the acetokinase family	buk2	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
WZS3_k127_3906259_0	1304284.L21TH_2285	2.425e-222	702.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
WZS3_k127_3906259_4	1476973.JMMB01000007_gene376	4.797e-30	135.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,24FPH@186801|Clostridia,25RAE@186804|Peptostreptococcaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
WZS3_k127_3906259_6	293826.Amet_4313	0.0009726	42.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,36DSC@31979|Clostridiaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
WZS3_k127_3916889_0	1304880.JAGB01000001_gene107	3.788e-211	672.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
WZS3_k127_3916889_1	1031288.AXAA01000007_gene870	1.456e-105	348.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,36EDU@31979|Clostridiaceae	186801|Clostridia	J	Methyltransferase	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
WZS3_k127_3916889_4	518637.EUBIFOR_02480	3.531e-34	138.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,3VQGG@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Chromate_transp
WZS3_k127_3916889_5	1301100.HG529251_gene6267	1.731e-31	130.0	COG2059@1|root,COG2059@2|Bacteria,1V3XK@1239|Firmicutes,25CID@186801|Clostridia,36I35@31979|Clostridiaceae	186801|Clostridia	P	overlaps another CDS with the same product name	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WZS3_k127_3916889_2	350688.Clos_1605	3.472e-51	186.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,36IRA@31979|Clostridiaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
WZS3_k127_3916889_3	926692.AZYG01000061_gene1378	1.9e-49	184.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WA8X@53433|Halanaerobiales	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
WZS3_k127_392889_2	1120985.AUMI01000014_gene1061	0.0007365	43.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,4H6HB@909932|Negativicutes	909932|Negativicutes	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD_5,PAS_9
WZS3_k127_392889_1	350688.Clos_2715	3.11e-23	101.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
WZS3_k127_392889_0	350688.Clos_2714	2.663e-290	903.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,36DF0@31979|Clostridiaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WZS3_k127_3930719_1	1410668.JNKC01000001_gene1607	7.816e-178	561.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,36EW8@31979|Clostridiaceae	186801|Clostridia	S	basic membrane	tmpC	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WZS3_k127_3930719_0	994573.T472_0208675	2.706e-286	884.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,36UI0@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WZS3_k127_3930719_2	1195236.CTER_5035	3.321e-175	557.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHM5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS3_k127_3930719_3	994573.T472_0208685	6.302e-175	552.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,36EJH@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS3_k127_3930719_4	273068.TTE1764	2.283e-15	78.0	COG1508@1|root,COG1508@2|Bacteria,1TQ0H@1239|Firmicutes,2480F@186801|Clostridia,42EW5@68295|Thermoanaerobacterales	186801|Clostridia	K	RNA polymerase sigma-54 factor	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
WZS3_k127_3941596_3	86416.Clopa_3054	4.012e-11	66.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,36JYR@31979|Clostridiaceae	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
WZS3_k127_3941596_1	479437.Elen_1633	5.756e-51	193.0	COG0272@1|root,COG0847@1|root,COG0272@2|Bacteria,COG0847@2|Bacteria,2IIG4@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T
WZS3_k127_3941596_2	1408422.JHYF01000015_gene370	6.292e-48	181.0	2A4QQ@1|root,30TC0@2|Bacteria,1V4P8@1239|Firmicutes,24ID5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3941596_0	1511.CLOST_0123	3.289e-140	467.0	COG3437@1|root,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes	1239|Firmicutes	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,HisKA_7TM,PAS,PAS_3,PAS_9
WZS3_k127_3949749_1	1408422.JHYF01000003_gene648	1.294e-141	455.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,36DGQ@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
WZS3_k127_3949749_0	293826.Amet_0652	6.005e-165	531.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,36E9J@31979|Clostridiaceae	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
WZS3_k127_3949749_2	663278.Ethha_2245	1.962e-05	50.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3WIYH@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WZS3_k127_3957899_0	1304284.L21TH_0079	4.097e-214	685.0	COG1057@1|root,COG1057@2|Bacteria,1TQVJ@1239|Firmicutes,249M0@186801|Clostridia,36DM4@31979|Clostridiaceae	186801|Clostridia	H	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
WZS3_k127_3957899_1	1304284.L21TH_0080	5.034e-92	316.0	COG0039@1|root,COG0039@2|Bacteria,1TQIV@1239|Firmicutes,248DK@186801|Clostridia,36GJF@31979|Clostridiaceae	186801|Clostridia	C	lactate/malate dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_1_N
WZS3_k127_3957899_2	941824.TCEL_01683	2.77e-45	173.0	COG0431@1|root,COG0431@2|Bacteria,1UYKJ@1239|Firmicutes,2485E@186801|Clostridia,36E7N@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WZS3_k127_3964584_1	1121324.CLIT_24c00070	7.556e-142	456.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,25QGP@186804|Peptostreptococcaceae	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WZS3_k127_3964584_0	324057.Pjdr2_0035	1.156e-149	487.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli,26RIB@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
WZS3_k127_3964584_2	1410624.JNKK01000008_gene1720	1.942e-08	56.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,27NTI@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
WZS3_k127_3966406_1	293826.Amet_4665	2.282e-128	423.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,36EM7@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0597 family	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
WZS3_k127_3966406_0	545243.BAEV01000015_gene1770	1.798e-281	885.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,36EC1@31979|Clostridiaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS3_k127_3976606_0	1121324.CLIT_20c00590	1.12e-265	827.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,25QRD@186804|Peptostreptococcaceae	186801|Clostridia	H	Formyltetrahydrofolate synthetase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WZS3_k127_3976606_2	857293.CAAU_2713	3.296e-73	255.0	COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,24AZ3@186801|Clostridia,36FKD@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
WZS3_k127_3976606_1	1469948.JPNB01000001_gene1681	8.33e-159	506.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,36DY4@31979|Clostridiaceae	186801|Clostridia	S	Permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
WZS3_k127_3978952_3	1410668.JNKC01000008_gene2730	7.773e-118	387.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,36EK3@31979|Clostridiaceae	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
WZS3_k127_3978952_1	1540257.JQMW01000013_gene1030	9.188e-161	516.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,36DN5@31979|Clostridiaceae	186801|Clostridia	F	Permease	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
WZS3_k127_3978952_6	1499689.CCNN01000014_gene3177	4.286e-39	155.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,36EEF@31979|Clostridiaceae	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
WZS3_k127_3978952_2	1408422.JHYF01000007_gene1322	8.723e-129	426.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,36DVM@31979|Clostridiaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_3978952_7	1540257.JQMW01000011_gene2607	1.383e-26	110.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,36MSQ@31979|Clostridiaceae	186801|Clostridia	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WZS3_k127_3978952_0	768706.Desor_2641	3.104e-170	539.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,2614E@186807|Peptococcaceae	186801|Clostridia	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WZS3_k127_3978952_5	871963.Desdi_0974	1.005e-39	151.0	COG0640@1|root,COG0640@2|Bacteria,1VCKP@1239|Firmicutes,24K7R@186801|Clostridia,265ZS@186807|Peptococcaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS3_k127_3978952_4	97138.C820_00501	5.881e-75	258.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,36ESG@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_3978952_8	1304284.L21TH_0630	2.558e-24	111.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DIS@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
WZS3_k127_4007850_1	350688.Clos_2644	1.393e-67	233.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,36G0N@31979|Clostridiaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WZS3_k127_4007850_0	1408422.JHYF01000012_gene3157	1.047e-147	491.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,36F91@31979|Clostridiaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WZS3_k127_4049070_0	1410653.JHVC01000002_gene4375	1.036e-212	670.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,36DHG@31979|Clostridiaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
WZS3_k127_4049160_1	31954.BPSP_0988	1.983e-05	49.0	COG0726@1|root,COG0726@2|Bacteria,2HEQK@201174|Actinobacteria,4D2RD@85004|Bifidobacteriales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
WZS3_k127_4049160_0	929506.CbC4_0126	3.116e-186	600.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,36DXA@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WZS3_k127_4068336_1	479433.Caci_6447	4.609e-09	59.0	COG2252@1|root,COG2252@2|Bacteria,2IC5Y@201174|Actinobacteria	201174|Actinobacteria	S	Xanthine uracil vitamin C permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
WZS3_k127_4068336_0	865861.AZSU01000003_gene2281	2.854e-33	137.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,36DJX@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS3_k127_4068336_2	1294142.CINTURNW_0371	0.0006339	46.0	COG1550@1|root,COG1550@2|Bacteria,1VEHY@1239|Firmicutes,24QJY@186801|Clostridia,36KRZ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
WZS3_k127_4069980_0	1408422.JHYF01000003_gene791	3.508e-210	679.0	COG1057@1|root,COG1057@2|Bacteria,1TQVJ@1239|Firmicutes,249M0@186801|Clostridia,36DM4@31979|Clostridiaceae	186801|Clostridia	H	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
WZS3_k127_4080258_0	1408422.JHYF01000006_gene1045	3.009e-178	575.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,36E60@31979|Clostridiaceae	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
WZS3_k127_4080258_6	536227.CcarbDRAFT_4527	6.608e-09	67.0	COG4241@1|root,COG4241@2|Bacteria,1V045@1239|Firmicutes,24BZJ@186801|Clostridia,36EI8@31979|Clostridiaceae	186801|Clostridia	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
WZS3_k127_4080258_3	1280689.AUJC01000014_gene1706	1.284e-26	109.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WZS3_k127_4080258_1	293826.Amet_2585	5.01e-52	188.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,36IQ6@31979|Clostridiaceae	186801|Clostridia	L	Single-stranded DNA-binding protein	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WZS3_k127_4080258_2	1408422.JHYF01000019_gene1421	9.454e-29	117.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,36JK5@31979|Clostridiaceae	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WZS3_k127_4080258_4	1123009.AUID01000012_gene1639	7.119e-19	88.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,269XP@186813|unclassified Clostridiales	186801|Clostridia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
WZS3_k127_4080258_5	500633.CLOHIR_02121	4.753e-09	60.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
WZS3_k127_4108514_0	1304284.L21TH_1766	1.156e-83	285.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,36FFE@31979|Clostridiaceae	186801|Clostridia	S	domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
WZS3_k127_4108514_1	1463934.JOCF01000038_gene2229	1.107e-20	107.0	COG1680@1|root,COG1680@2|Bacteria,2GNNF@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
WZS3_k127_4110843_0	1408422.JHYF01000003_gene917	3.311e-162	517.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,36DRZ@31979|Clostridiaceae	186801|Clostridia	Q	imidazolonepropionase activity	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
WZS3_k127_4110843_2	1304284.L21TH_1972	3.629e-56	202.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,36JRA@31979|Clostridiaceae	186801|Clostridia	E	cyclohydrolase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
WZS3_k127_4110843_1	1128398.Curi_c06290	1.417e-66	236.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,2680P@186813|unclassified Clostridiales	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_4111202_3	1294142.CINTURNW_3403	7.7e-16	80.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,36F3I@31979|Clostridiaceae	186801|Clostridia	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_4111202_1	1408422.JHYF01000016_gene123	1.742e-181	572.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,36E72@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
WZS3_k127_4111202_2	1414720.CBYM010000010_gene3219	4.962e-116	381.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,36DCU@31979|Clostridiaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS3_k127_4111202_0	1304284.L21TH_0120	2.478e-200	630.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,36DKE@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
WZS3_k127_4134493_2	515635.Dtur_1103	1.478e-08	63.0	COG1555@1|root,COG1596@1|root,COG1555@2|Bacteria,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	comEA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01991,ko:K02237	ko02026,map02026	M00429	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.18,3.A.11.1,3.A.11.2	-	-	HHH_3,Poly_export,SLBB
WZS3_k127_4134493_0	1128398.Curi_c19730	2.414e-84	297.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,2690V@186813|unclassified Clostridiales	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
WZS3_k127_4134493_1	70601.3257265	8.851e-44	162.0	COG0251@1|root,arCOG01630@2157|Archaea,2XXUZ@28890|Euryarchaeota,244C0@183968|Thermococci	183968|Thermococci	J	Endoribonuclease L-PSP	-	GO:0003674,GO:0003824,GO:0016787,GO:0019239	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
WZS3_k127_4139013_0	1298920.KI911353_gene4456	1.326e-61	217.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,21Y4V@1506553|Lachnoclostridium	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_3
WZS3_k127_4139013_1	767817.Desgi_3508	7.565e-45	164.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VWA
WZS3_k127_4139013_2	1321778.HMPREF1982_03451	4.966e-44	162.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia,26AMU@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VWA
WZS3_k127_4139013_3	1286171.EAL2_808p00310	3.012e-34	132.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,25UV0@186806|Eubacteriaceae	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Macro
WZS3_k127_415152_0	1540257.JQMW01000009_gene2836	1.629e-76	269.0	COG2199@1|root,COG2199@2|Bacteria,1V5WD@1239|Firmicutes,249N6@186801|Clostridia,36HFR@31979|Clostridiaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HisKA_7TM,PAS_9
WZS3_k127_415152_1	1410653.JHVC01000003_gene3947	7.375e-10	66.0	COG0457@1|root,COG5263@1|root,COG5513@1|root,COG0457@2|Bacteria,COG5263@2|Bacteria,COG5513@2|Bacteria,1TSIS@1239|Firmicutes,25EBW@186801|Clostridia,36UJT@31979|Clostridiaceae	186801|Clostridia	KLT	Protein of unknown function (DUF3298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,WG_beta_rep
WZS3_k127_4153721_0	1410670.JHXF01000006_gene1153	1.349e-148	503.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia,3WHJ5@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
WZS3_k127_4153721_1	1121289.JHVL01000023_gene95	2.037e-102	342.0	COG1215@1|root,COG1215@2|Bacteria,1UI5W@1239|Firmicutes,25EJ5@186801|Clostridia,36US3@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
WZS3_k127_4153721_2	203119.Cthe_2152	9.298e-27	113.0	2ERG0@1|root,33J1J@2|Bacteria,1VK5G@1239|Firmicutes,24WJ2@186801|Clostridia,3WQQ7@541000|Ruminococcaceae	186801|Clostridia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WZS3_k127_4188349_1	1031288.AXAA01000022_gene1585	1.778e-93	310.0	COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia,36G6C@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the beta-eliminating lyase family	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WZS3_k127_4188349_3	431943.CKL_0615	7.133e-42	162.0	COG2964@1|root,COG2964@2|Bacteria,1V2VD@1239|Firmicutes,24GH7@186801|Clostridia,36GYC@31979|Clostridiaceae	186801|Clostridia	S	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
WZS3_k127_4188349_4	397948.Cmaq_1216	2.441e-38	154.0	COG1506@1|root,arCOG01646@2157|Archaea	2157|Archaea	E	Peptidase S9 prolyl oligopeptidase active site	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
WZS3_k127_4188349_0	1469948.JPNB01000002_gene3370	1.228e-192	607.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,36E70@31979|Clostridiaceae	186801|Clostridia	C	flavodoxin nitric oxide synthase	norV	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
WZS3_k127_4188349_2	573061.Clocel_3592	5.637e-44	164.0	COG2846@1|root,COG2846@2|Bacteria,1UYJV@1239|Firmicutes,24GZI@186801|Clostridia,36FII@31979|Clostridiaceae	186801|Clostridia	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
WZS3_k127_4189571_1	1123489.AUAN01000003_gene1226	1.377e-06	60.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4H52P@909932|Negativicutes	909932|Negativicutes	K	Transcriptional regulator, ArsR family	czrA	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS3_k127_4189571_0	350688.Clos_2223	8.52e-47	175.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,36UJE@31979|Clostridiaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
WZS3_k127_4192861_5	189425.PGRAT_25225	2.132e-07	59.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,26SMZ@186822|Paenibacillaceae	91061|Bacilli	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WZS3_k127_4192861_3	1408823.AXUS01000003_gene498	9.337e-45	175.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,25QPQ@186804|Peptostreptococcaceae	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WZS3_k127_4192861_4	272563.CD630_24730	2.118e-20	93.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,25RNU@186804|Peptostreptococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
WZS3_k127_4192861_0	1408422.JHYF01000002_gene2422	4.604e-295	915.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,36EZX@31979|Clostridiaceae	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WZS3_k127_4192861_1	1128398.Curi_c18310	7.376e-107	358.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,267TN@186813|unclassified Clostridiales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WZS3_k127_4192861_2	1280692.AUJL01000005_gene1678	1.443e-60	218.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,36DW8@31979|Clostridiaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
WZS3_k127_4195053_2	1408422.JHYF01000004_gene1468	4.066e-200	629.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,36ET7@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WZS3_k127_4195053_3	1121289.JHVL01000076_gene566	7.727e-20	91.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,24QMG@186801|Clostridia	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
WZS3_k127_4195053_0	1408422.JHYF01000004_gene1470	1.68e-295	919.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,36G29@31979|Clostridiaceae	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
WZS3_k127_4195053_1	857293.CAAU_0894	5.662e-243	770.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,36E8U@31979|Clostridiaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WZS3_k127_4195053_4	1120970.AUBZ01000002_gene740	3.384e-12	70.0	COG0561@1|root,COG0561@2|Bacteria,1RDYP@1224|Proteobacteria,1S0EU@1236|Gammaproteobacteria,466DU@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_4195373_0	1121335.Clst_0646	0.0	1276.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WMY3@541000|Ruminococcaceae	186801|Clostridia	C	Domain of unknown function	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
WZS3_k127_4195373_1	1121289.JHVL01000089_gene1825	8.084e-27	111.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,36F1U@31979|Clostridiaceae	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
WZS3_k127_4195665_4	1121289.JHVL01000018_gene599	2.046e-28	118.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,36DG7@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WZS3_k127_4195665_1	1094508.Tsac_1943	3.2e-136	446.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,42FGQ@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WZS3_k127_4195665_5	1262449.CP6013_3356	9.761e-10	65.0	COG1846@1|root,COG1846@2|Bacteria,1VN3F@1239|Firmicutes,24N5Q@186801|Clostridia,36KYH@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_4195665_3	1392502.JNIO01000002_gene156	8.92e-70	247.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,4H26X@909932|Negativicutes	909932|Negativicutes	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
WZS3_k127_4195665_0	555079.Toce_1349	9.661e-199	635.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,42F6I@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the UbiD family	-	-	4.1.1.61,4.1.1.98	ko:K03182,ko:K16239	ko00130,ko00627,ko01100,ko01110,ko01120,map00130,map00627,map01100,map01110,map01120	M00117	R01238,R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
WZS3_k127_4195665_2	697281.Mahau_2237	1.893e-96	323.0	COG0382@1|root,COG0382@2|Bacteria,1TQU5@1239|Firmicutes,2486B@186801|Clostridia,42F54@68295|Thermoanaerobacterales	186801|Clostridia	H	COGs COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WZS3_k127_4195665_6	1122217.KB899573_gene2126	0.0003573	48.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,4H44P@909932|Negativicutes	909932|Negativicutes	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
WZS3_k127_4195741_0	1499689.CCNN01000015_gene3418	3.083e-133	440.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,36E9N@31979|Clostridiaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
WZS3_k127_4195741_1	1033744.CAEL01000015_gene45	1.697e-29	118.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,22HPG@1570339|Peptoniphilaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WZS3_k127_4203157_0	1408422.JHYF01000003_gene934	2.813e-54	193.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,36FVM@31979|Clostridiaceae	186801|Clostridia	S	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
WZS3_k127_4203157_5	457396.CSBG_02508	1.31e-15	83.0	COG3238@1|root,COG3238@2|Bacteria,1V7PX@1239|Firmicutes,24MM7@186801|Clostridia,36KFC@31979|Clostridiaceae	186801|Clostridia	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
WZS3_k127_4203157_4	1321778.HMPREF1982_03446	1.707e-16	84.0	COG3238@1|root,COG3238@2|Bacteria,1V6I0@1239|Firmicutes,24MVN@186801|Clostridia,26BHK@186813|unclassified Clostridiales	186801|Clostridia	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
WZS3_k127_4203157_2	1410653.JHVC01000019_gene2145	1.896e-38	153.0	COG0664@1|root,COG0664@2|Bacteria,1V2AH@1239|Firmicutes,24H46@186801|Clostridia,36IIT@31979|Clostridiaceae	186801|Clostridia	K	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
WZS3_k127_4203157_3	293826.Amet_4061	3.798e-26	123.0	COG5401@1|root,COG5401@2|Bacteria,1VWMY@1239|Firmicutes,251X0@186801|Clostridia,36S1V@31979|Clostridiaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
WZS3_k127_4203157_1	350688.Clos_0659	4.621e-44	172.0	COG4942@1|root,COG4942@2|Bacteria,1VR95@1239|Firmicutes,24HB3@186801|Clostridia	186801|Clostridia	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_422640_1	293826.Amet_0483	4.503e-90	316.0	COG4187@1|root,COG4187@2|Bacteria,1TQQ7@1239|Firmicutes,249CV@186801|Clostridia,36EX1@31979|Clostridiaceae	186801|Clostridia	E	Peptidase family M20/M25/M40	rocB	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M20
WZS3_k127_422640_0	1304284.L21TH_2172	2.107e-105	347.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,36DYK@31979|Clostridiaceae	186801|Clostridia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
WZS3_k127_4236642_3	1321778.HMPREF1982_03066	1.026e-21	95.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia,26A5P@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WZS3_k127_4236642_1	509191.AEDB02000109_gene4951	2.22e-78	268.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3WG7D@541000|Ruminococcaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WZS3_k127_4236642_2	580331.Thit_1262	8.833e-76	267.0	COG1243@1|root,COG1243@2|Bacteria,1TS1F@1239|Firmicutes,248YV@186801|Clostridia,42F40@68295|Thermoanaerobacterales	186801|Clostridia	BK	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,Radical_SAM_C
WZS3_k127_4236642_0	1128398.Curi_c16270	6.574e-148	493.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,267UY@186813|unclassified Clostridiales	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
WZS3_k127_4237880_0	1321778.HMPREF1982_02225	3.621e-129	426.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,268EB@186813|unclassified Clostridiales	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
WZS3_k127_4237880_1	344747.PM8797T_27914	7.685e-39	150.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2IXGZ@203682|Planctomycetes	203682|Planctomycetes	M	cyanophycin synthetase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS3_k127_4268129_0	1304284.L21TH_2708	3.139e-187	592.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,36DGG@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WZS3_k127_4313743_2	632292.Calhy_0863	5.342e-26	124.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,42F11@68295|Thermoanaerobacterales	186801|Clostridia	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WZS3_k127_4313743_0	293826.Amet_3064	7.663e-43	165.0	COG0827@1|root,COG0827@2|Bacteria,1UHWQ@1239|Firmicutes,25E5N@186801|Clostridia,36UQ7@31979|Clostridiaceae	186801|Clostridia	LV	TaqI-like C-terminal specificity domain	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,HSDR_N,HTH_17,N6_Mtase,TaqI_C
WZS3_k127_4313743_1	293826.Amet_3064	1.827e-32	140.0	COG0827@1|root,COG0827@2|Bacteria,1UHWQ@1239|Firmicutes,25E5N@186801|Clostridia,36UQ7@31979|Clostridiaceae	186801|Clostridia	LV	TaqI-like C-terminal specificity domain	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,HSDR_N,HTH_17,N6_Mtase,TaqI_C
WZS3_k127_4327786_2	994573.T472_0204460	1.722e-07	53.0	COG1807@1|root,COG1807@2|Bacteria,1V0HR@1239|Firmicutes,24BAC@186801|Clostridia,36NEI@31979|Clostridiaceae	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
WZS3_k127_4327786_0	994573.T472_0202085	1.956e-140	457.0	COG0151@1|root,COG0151@2|Bacteria,1TRZ2@1239|Firmicutes,2497Y@186801|Clostridia,36JR5@31979|Clostridiaceae	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,GARS_A
WZS3_k127_4327786_1	994573.T472_0202080	6.644e-47	173.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,25B01@186801|Clostridia,36JNT@31979|Clostridiaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012,ko:K20534	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8,4.D.2.1.9	GT2	-	Glycos_transf_2
WZS3_k127_4335967_1	1449050.JNLE01000003_gene2544	1.122e-40	151.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,36F1U@31979|Clostridiaceae	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
WZS3_k127_4335967_0	574087.Acear_0516	3.148e-117	386.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
WZS3_k127_4335967_2	1410668.JNKC01000001_gene1433	1.129e-08	57.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
WZS3_k127_4336100_1	754027.HMPREF9554_01706	1.354e-27	118.0	COG3862@1|root,COG3862@2|Bacteria,2J872@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
WZS3_k127_4336100_0	1408422.JHYF01000003_gene664	4.358e-208	654.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,36E6C@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WZS3_k127_4359061_0	1304284.L21TH_1226	1.933e-82	286.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia,36GJU@31979|Clostridiaceae	186801|Clostridia	N	flagellar basal body	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WZS3_k127_4359061_1	350688.Clos_2549	8.56e-79	271.0	COG4786@1|root,COG4786@2|Bacteria,1TT5Z@1239|Firmicutes,248M9@186801|Clostridia,36EXN@31979|Clostridiaceae	186801|Clostridia	N	flagellar basal body	flgG	-	-	ko:K02390,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WZS3_k127_4359061_3	1347392.CCEZ01000007_gene2093	7.092e-12	71.0	COG3951@1|root,COG3951@2|Bacteria,1VFX2@1239|Firmicutes,24RKJ@186801|Clostridia,36NM5@31979|Clostridiaceae	186801|Clostridia	MNO	Rod binding protein	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Rod-binding
WZS3_k127_4359061_2	926561.KB900623_gene808	4.624e-32	132.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,247V3@186801|Clostridia,3WB5U@53433|Halanaerobiales	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WZS3_k127_4374934_1	138119.DSY3068	5.939e-34	135.0	COG0644@1|root,COG0644@2|Bacteria,1UZT1@1239|Firmicutes,25DJ8@186801|Clostridia	186801|Clostridia	C	oxidoreductase	cbrA	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8
WZS3_k127_4374934_3	1174504.AJTN02000184_gene193	7.803e-28	119.0	293T3@1|root,2ZR8H@2|Bacteria,1V593@1239|Firmicutes,4HG8Q@91061|Bacilli,1ZFS5@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
WZS3_k127_4374934_2	1235279.C772_00877	7.927e-30	119.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli,26FRS@186818|Planococcaceae	91061|Bacilli	K	Transcriptional regulator	yozG	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
WZS3_k127_4374934_4	720554.Clocl_1080	6.593e-19	89.0	2CIYP@1|root,33JA9@2|Bacteria,1VN0I@1239|Firmicutes,24WU9@186801|Clostridia,3WMFH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4374934_0	1031288.AXAA01000010_gene458	1.386e-82	276.0	28H6R@1|root,2Z7J3@2|Bacteria,1TQ2I@1239|Firmicutes,247QF@186801|Clostridia,36EPD@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4375474_4	1033810.HLPCO_002325	1.303e-78	274.0	COG2308@1|root,COG2308@2|Bacteria,2NR97@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2,GSP_synth
WZS3_k127_4375474_1	1293054.HSACCH_01724	1.905e-84	295.0	COG3572@1|root,COG3572@2|Bacteria,1U9WJ@1239|Firmicutes,249F7@186801|Clostridia,3WAAD@53433|Halanaerobiales	186801|Clostridia	H	PFAM Glutamate-cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
WZS3_k127_4375474_3	350688.Clos_1404	1.794e-80	290.0	COG1835@1|root,COG1835@2|Bacteria,1V0J2@1239|Firmicutes,247YD@186801|Clostridia,36EK5@31979|Clostridiaceae	186801|Clostridia	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
WZS3_k127_4375474_5	931626.Awo_c01100	3.936e-78	269.0	COG1277@1|root,COG1277@2|Bacteria,1V6DZ@1239|Firmicutes,249IM@186801|Clostridia,25Z71@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WZS3_k127_4375474_0	931626.Awo_c01110	2.754e-94	316.0	COG1277@1|root,COG1277@2|Bacteria,1V6DZ@1239|Firmicutes,249IM@186801|Clostridia,25Z71@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WZS3_k127_4375474_2	931626.Awo_c01120	8.714e-81	273.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,25VYG@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_4377088_0	1121121.KB894284_gene428	4.29e-65	230.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4ISAE@91061|Bacilli,26T5P@186822|Paenibacillaceae	91061|Bacilli	C	Reduces fumarate to succinate in anaerobic bacterial respiration	-	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red,Succ_DH_flav_C
WZS3_k127_4377088_1	1294142.CINTURNW_4028	7.555e-48	180.0	COG4565@1|root,COG4565@2|Bacteria,1V49R@1239|Firmicutes,24BJS@186801|Clostridia,36HG7@31979|Clostridiaceae	186801|Clostridia	KT	transcriptional regulatory protein	-	-	-	ko:K02475,ko:K11615,ko:K11692,ko:K11712	ko02020,map02020	M00489,M00490	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_11,HTH_IclR,Response_reg
WZS3_k127_4377088_2	398511.BpOF4_18125	1.842e-09	60.0	COG3290@1|root,COG3290@2|Bacteria,1TQJR@1239|Firmicutes,4H9Q0@91061|Bacilli,1ZBHV@1386|Bacillus	91061|Bacilli	T	Signal transduction histidine kinase regulating citrate malate metabolism	malK	-	2.7.13.3	ko:K11614,ko:K11637	ko02020,map02020	M00487,M00490	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,PAS,SPOB_a,sCache_3_2
WZS3_k127_4383329_2	1511.CLOST_0831	2.044e-52	201.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25T7D@186804|Peptostreptococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WZS3_k127_4383329_0	357809.Cphy_1245	8.545e-128	419.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,21ZG5@1506553|Lachnoclostridium	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
WZS3_k127_4383329_1	158190.SpiGrapes_0999	6.841e-71	251.0	COG0419@1|root,COG0419@2|Bacteria,2J5P4@203691|Spirochaetes	203691|Spirochaetes	L	Exonuclease SbcC	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
WZS3_k127_4387633_2	457405.FSDG_02083	1.105e-15	77.0	COG0579@1|root,COG1251@1|root,COG0579@2|Bacteria,COG1251@2|Bacteria,378T7@32066|Fusobacteria	32066|Fusobacteria	C	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
WZS3_k127_4387633_0	865861.AZSU01000009_gene629	2.882e-250	779.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,36EMF@31979|Clostridiaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WZS3_k127_4387633_1	1511.CLOST_2060	1.747e-68	246.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
WZS3_k127_4397859_4	1121289.JHVL01000006_gene2875	1.191e-52	192.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,36E34@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WZS3_k127_4397859_1	1304284.L21TH_1510	1.227e-80	274.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24FYY@186801|Clostridia,36F85@31979|Clostridiaceae	186801|Clostridia	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WZS3_k127_4397859_7	1280688.AUJB01000008_gene808	1.092e-19	94.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,3NHAW@46205|Pseudobutyrivibrio	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
WZS3_k127_4397859_6	938278.CAJO01000046_gene360	6.562e-28	119.0	2AFD1@1|root,32SWC@2|Bacteria,1VBNF@1239|Firmicutes,24P3N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4397859_2	1408422.JHYF01000008_gene3731	3.755e-80	273.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,36DUA@31979|Clostridiaceae	186801|Clostridia	S	PFAM Metallophosphoesterase	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
WZS3_k127_4397859_5	1121324.CLIT_10c03930	1.207e-51	191.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia	186801|Clostridia	H	Belongs to the TtcA family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
WZS3_k127_4397859_0	941824.TCEL_01695	1.207e-102	341.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,36DM9@31979|Clostridiaceae	186801|Clostridia	T	RelA SpoT domain protein	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
WZS3_k127_4397859_3	1122919.KB905565_gene2664	1.34e-57	207.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli	91061|Bacilli	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,LysM,Metallophos,SLH
WZS3_k127_4411384_0	1321778.HMPREF1982_00244	1.583e-170	541.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,248U7@186801|Clostridia,268C7@186813|unclassified Clostridiales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WZS3_k127_4412898_2	272563.CD630_30640	4.342e-157	499.0	COG2115@1|root,COG2115@2|Bacteria,1TQW2@1239|Firmicutes,24869@186801|Clostridia	186801|Clostridia	G	Belongs to the xylose isomerase family	xylA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08960	AP_endonuc_2
WZS3_k127_4412898_3	293826.Amet_3795	3.575e-90	311.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,25BAH@186801|Clostridia,36FQ6@31979|Clostridiaceae	186801|Clostridia	GK	ROK family	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
WZS3_k127_4412898_1	293826.Amet_3794	3.835e-184	587.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,36F3K@31979|Clostridiaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WZS3_k127_4412898_0	293826.Amet_1445	2.273e-187	595.0	COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,24CKX@186801|Clostridia,36GSW@31979|Clostridiaceae	186801|Clostridia	S	Hemerythrin HHE cation binding domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF438,Hemerythrin,PAS_10
WZS3_k127_4429446_0	1540257.JQMW01000011_gene1876	2.867e-164	526.0	COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,247QD@186801|Clostridia,36EAH@31979|Clostridiaceae	186801|Clostridia	C	Citrate lyase alpha subunit	-	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	CitF
WZS3_k127_4429446_1	666686.B1NLA3E_22075	9.185e-117	382.0	COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,4HD40@91061|Bacilli,1ZFEY@1386|Bacillus	91061|Bacilli	G	HpcH/HpaI aldolase/citrate lyase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
WZS3_k127_4429446_7	1540257.JQMW01000011_gene1878	1.118e-21	97.0	COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,24QMJ@186801|Clostridia,36N6K@31979|Clostridiaceae	186801|Clostridia	C	Covalent carrier of the coenzyme of citrate lyase	citD	-	-	ko:K01646	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001	-	-	-	ACP
WZS3_k127_4429446_3	1408422.JHYF01000004_gene1622	4.613e-78	274.0	COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,248Y4@186801|Clostridia,36EF0@31979|Clostridiaceae	186801|Clostridia	C	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase	citC	-	6.2.1.22	ko:K01910	ko02020,map02020	-	R04449	RC00012,RC00039	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_10,Citrate_ly_lig
WZS3_k127_4429446_6	768706.Desor_4454	4.352e-53	198.0	COG1767@1|root,COG1767@2|Bacteria,1TQGQ@1239|Firmicutes,24BQH@186801|Clostridia	186801|Clostridia	H	synthase	citG	-	2.4.2.52,2.7.7.61	ko:K05966,ko:K13927	ko02020,map02020	-	R09675,R10706	RC00049,RC00063	ko00000,ko00001,ko01000	-	-	-	CitG,CitX
WZS3_k127_4429446_2	645991.Sgly_0898	2.298e-79	270.0	COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,24ACS@186801|Clostridia,2632G@186807|Peptococcaceae	186801|Clostridia	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
WZS3_k127_4429446_4	720554.Clocl_3393	2.931e-73	254.0	COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,248AA@186801|Clostridia,3WHIK@541000|Ruminococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WZS3_k127_4429446_8	1123054.KB907714_gene624	2.493e-05	53.0	COG5018@1|root,COG5018@2|Bacteria,1RE77@1224|Proteobacteria,1S8NC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
WZS3_k127_4429446_5	1298920.KI911353_gene3166	2.542e-60	210.0	COG0288@1|root,COG0288@2|Bacteria,1V1EC@1239|Firmicutes,2495A@186801|Clostridia,21YEY@1506553|Lachnoclostridium	186801|Clostridia	H	Reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
WZS3_k127_4431729_0	350688.Clos_2783	3.192e-145	480.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36DIS@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	yycG	-	2.7.13.3	ko:K07636,ko:K07652	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,PAS_9
WZS3_k127_4431729_1	293826.Amet_4758	3.068e-107	351.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,36W97@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	walR	-	-	ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_4431729_2	350688.Clos_2792	5.013e-86	297.0	COG0739@1|root,COG3583@1|root,COG0739@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia,36HF8@31979|Clostridiaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
WZS3_k127_4440753_1	635013.TherJR_0821	4.857e-67	239.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,261VD@186807|Peptococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WZS3_k127_4440753_0	1321784.HMPREF1987_00343	2.494e-101	336.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,25QUV@186804|Peptostreptococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
WZS3_k127_4444507_0	1121335.Clst_2203	4.19e-213	668.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
WZS3_k127_4446438_2	701347.Entcl_1533	6.911e-27	111.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,1SCG7@1236|Gammaproteobacteria,3X2T9@547|Enterobacter	1236|Gammaproteobacteria	S	Putative zinc- or iron-chelating domain	yeiW	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
WZS3_k127_4446438_1	1499689.CCNN01000015_gene3374	3.445e-133	436.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,36FFH@31979|Clostridiaceae	186801|Clostridia	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WZS3_k127_4446438_0	1286171.EAL2_808p03340	2.235e-186	597.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,25V5B@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS3_k127_4449045_1	498761.HM1_0474	1.216e-159	514.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS3_k127_4449045_0	720554.Clocl_0672	3.815e-194	613.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
WZS3_k127_4449045_4	1304284.L21TH_2374	7.112e-93	308.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,36ED5@31979|Clostridiaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
WZS3_k127_4449045_3	1292035.H476_3093	2.415e-121	402.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,25R85@186804|Peptostreptococcaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WZS3_k127_4449045_2	1128398.Curi_c06300	3.417e-136	456.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,268AA@186813|unclassified Clostridiales	186801|Clostridia	L	AAA domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WZS3_k127_4449045_5	266117.Rxyl_1424	0.0003431	49.0	COG2137@1|root,COG2137@2|Bacteria	2|Bacteria	S	regulation of DNA repair	recX	GO:0003674,GO:0005575,GO:0005623,GO:0005886,GO:0006282,GO:0008150,GO:0016020,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0044464,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
WZS3_k127_445914_2	1304284.L21TH_1732	1.496e-125	414.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,36DQZ@31979|Clostridiaceae	186801|Clostridia	J	metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
WZS3_k127_445914_3	1121324.CLIT_23c04670	4.111e-124	415.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia,25TB7@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
WZS3_k127_445914_4	1280390.CBQR020000010_gene254	2.547e-73	252.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli,26R34@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU15560	Pribosyltran
WZS3_k127_445914_5	482234.SCAZ3_09215	1.448e-70	244.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli	91061|Bacilli	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
WZS3_k127_445914_0	1121289.JHVL01000024_gene125	3.384e-172	554.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,36EA0@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
WZS3_k127_445914_7	350688.Clos_1083	1.035e-30	126.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,36K1I@31979|Clostridiaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WZS3_k127_445914_6	1511.CLOST_0235	2.083e-57	213.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia	186801|Clostridia	K	TIGRFAM cell envelope-related function transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
WZS3_k127_445914_1	865861.AZSU01000007_gene1102	2.691e-134	442.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,36DVH@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS3_k127_4468164_0	350688.Clos_2872	1.226e-155	503.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,36ECR@31979|Clostridiaceae	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WZS3_k127_4468164_1	1321814.HMPREF9089_00751	7.835e-121	394.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,25UR2@186806|Eubacteriaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
WZS3_k127_4473418_1	272563.CD630_29640	3.594e-48	181.0	COG3382@1|root,COG3382@2|Bacteria,1V7YR@1239|Firmicutes,24JVZ@186801|Clostridia,25SD3@186804|Peptostreptococcaceae	186801|Clostridia	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
WZS3_k127_4473418_0	1449050.JNLE01000005_gene5211	2.463e-68	237.0	COG1246@1|root,COG1246@2|Bacteria,1V9D3@1239|Firmicutes,24DYK@186801|Clostridia,36HXT@31979|Clostridiaceae	186801|Clostridia	E	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_4473418_2	1286171.EAL2_c00470	1.18e-37	158.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,25YQ9@186806|Eubacteriaceae	186801|Clostridia	C	Na+/H+ antiporter family	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
WZS3_k127_4489416_2	457570.Nther_2811	4.832e-40	153.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia	186801|Clostridia	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
WZS3_k127_4489416_0	1033734.CAET01000045_gene594	5.416e-211	669.0	COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,4HB23@91061|Bacilli,1ZCVJ@1386|Bacillus	91061|Bacilli	E	gamma-glutamyltransferase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
WZS3_k127_4489416_1	428125.CLOLEP_03786	7.265e-46	170.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
WZS3_k127_4491699_1	1195236.CTER_3096	1.262e-29	123.0	COG2227@1|root,COG2227@2|Bacteria,1UXZZ@1239|Firmicutes,24BIT@186801|Clostridia	186801|Clostridia	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS3_k127_4491699_3	768706.Desor_3850	3.812e-06	51.0	2ESFA@1|root,33K01@2|Bacteria,1VKIX@1239|Firmicutes,24WH7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4491699_2	1230342.CTM_08026	7.797e-19	94.0	COG1309@1|root,COG1309@2|Bacteria,1VDSK@1239|Firmicutes,24MTE@186801|Clostridia,36JUY@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_4491699_0	293826.Amet_2183	1.669e-77	264.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,36RPF@31979|Clostridiaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366,ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
WZS3_k127_449309_4	203119.Cthe_1846	1.502e-88	302.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WN3N@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_449309_6	1195236.CTER_0704	1.665e-81	277.0	COG0745@1|root,COG0745@2|Bacteria,1U3FH@1239|Firmicutes,248BR@186801|Clostridia	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_449309_1	398512.JQKC01000008_gene942	7.315e-153	496.0	COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,249HC@186801|Clostridia,3WNAJ@541000|Ruminococcaceae	186801|Clostridia	P	Cytochrome C biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
WZS3_k127_449309_9	1195236.CTER_3739	2.812e-35	142.0	COG0454@1|root,COG0456@2|Bacteria,1UN03@1239|Firmicutes,24MKD@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
WZS3_k127_449309_10	866895.HBHAL_1516	1.063e-29	123.0	COG4818@1|root,COG4818@2|Bacteria,1VG59@1239|Firmicutes,4HP4V@91061|Bacilli	91061|Bacilli	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_449309_5	1120998.AUFC01000006_gene899	1.5e-84	286.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,3WDCG@538999|Clostridiales incertae sedis	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
WZS3_k127_449309_11	1408422.JHYF01000006_gene1193	2.49e-22	100.0	COG1977@1|root,COG1977@2|Bacteria,1VIST@1239|Firmicutes,24QYP@186801|Clostridia,36NC4@31979|Clostridiaceae	186801|Clostridia	H	ThiS family	moaD	-	-	-	-	-	-	-	-	-	-	-	ThiS
WZS3_k127_449309_3	536227.CcarbDRAFT_3462	9.562e-99	334.0	COG0535@1|root,COG0535@2|Bacteria,1V0CR@1239|Firmicutes,24BIB@186801|Clostridia,36G4D@31979|Clostridiaceae	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WZS3_k127_449309_0	293826.Amet_4643	7.406e-297	919.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,36FZW@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	aor	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS09915	AFOR_C,AFOR_N
WZS3_k127_449309_7	1033737.CAEV01000062_gene3040	1.502e-65	227.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,24HBA@186801|Clostridia,36IV7@31979|Clostridiaceae	186801|Clostridia	H	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
WZS3_k127_449309_8	1128398.Curi_c29230	2.002e-58	207.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,2699T@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
WZS3_k127_449309_2	1128398.Curi_c29240	9.085e-119	389.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,268QR@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
WZS3_k127_4509322_1	1235835.C814_01098	1.631e-52	196.0	COG0739@1|root,COG0739@2|Bacteria,1V7QV@1239|Firmicutes,24M4A@186801|Clostridia,3WPC6@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WZS3_k127_4509322_0	756499.Desde_0514	1.429e-314	982.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1TSAC@1239|Firmicutes,25EIJ@186801|Clostridia,261GW@186807|Peptococcaceae	186801|Clostridia	L	Eukaryotic and archaeal DNA primase small subunit	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
WZS3_k127_4516581_2	536233.CLO_2598	5.813e-75	257.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,36EVE@31979|Clostridiaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WZS3_k127_4516581_1	1304284.L21TH_0661	4.787e-78	271.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,36ED0@31979|Clostridiaceae	186801|Clostridia	S	tigr00255	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
WZS3_k127_4516581_0	1304284.L21TH_0659	2.537e-138	460.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,36DS7@31979|Clostridiaceae	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
WZS3_k127_4527165_0	509191.AEDB02000018_gene226	3.559e-75	266.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3WIEH@541000|Ruminococcaceae	186801|Clostridia	G	Periplasmic binding protein domain	xylF	-	3.6.3.17	ko:K10543,ko:K10820	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
WZS3_k127_4527165_1	1033810.HLPCO_000720	1.973e-24	104.0	COG1609@1|root,COG1609@2|Bacteria,2NQU6@2323|unclassified Bacteria	2|Bacteria	K	Bacterial regulatory proteins, lacI family	msmR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_4532554_0	1511.CLOST_1647	2.824e-199	634.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,25QHI@186804|Peptostreptococcaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
WZS3_k127_4532554_2	1151292.QEW_0821	2.801e-27	113.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,25QP0@186804|Peptostreptococcaceae	186801|Clostridia	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
WZS3_k127_4532554_1	445973.CLOBAR_01324	2.276e-43	162.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,25QP0@186804|Peptostreptococcaceae	186801|Clostridia	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
WZS3_k127_4534338_3	1002367.HMPREF0673_00744	4.794e-12	68.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,2G38B@200643|Bacteroidia	976|Bacteroidetes	S	Psort location Cytoplasmic, score	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WZS3_k127_4534338_4	1121121.KB894304_gene3286	1.034e-06	60.0	28ZZ3@1|root,2ZMPH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4534338_2	350688.Clos_1671	2.343e-52	188.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,36J5P@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WZS3_k127_4534338_0	350688.Clos_1670	1.343e-174	555.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,36DXY@31979|Clostridiaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS3_k127_4534338_1	293826.Amet_2454	1.548e-63	220.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,36I0X@31979|Clostridiaceae	186801|Clostridia	C	FeS cluster assembly scaffold protein NifU	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WZS3_k127_4554838_4	1408422.JHYF01000017_gene1835	2.996e-32	127.0	COG0700@1|root,COG0700@2|Bacteria	2|Bacteria	S	Nucleoside recognition	yjiG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Gate
WZS3_k127_4554838_0	1121324.CLIT_4c01730	1.539e-99	330.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia,25QES@186804|Peptostreptococcaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA_1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WZS3_k127_4554838_3	1131462.DCF50_p2397	1.441e-37	144.0	2EG8Z@1|root,32UBD@2|Bacteria,1VBQD@1239|Firmicutes,24NWB@186801|Clostridia,265M4@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4554838_2	679926.Mpet_1639	3.42e-45	172.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y4MT@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
WZS3_k127_4554838_5	1236976.JCM16418_581	1.203e-09	66.0	2EBE8@1|root,335EW@2|Bacteria,1VI0V@1239|Firmicutes,4HQUP@91061|Bacilli,26ZQD@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4554838_1	1286171.EAL2_808p06840	2.4e-45	168.0	COG0262@1|root,COG0262@2|Bacteria,1VAUA@1239|Firmicutes,24G7Y@186801|Clostridia,25X6D@186806|Eubacteriaceae	186801|Clostridia	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
WZS3_k127_457577_0	1304284.L21TH_0784	5.038e-285	880.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,36DSA@31979|Clostridiaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
WZS3_k127_4587819_5	443254.Marpi_0685	1.333e-154	497.0	COG0426@1|root,COG0426@2|Bacteria,2GCAS@200918|Thermotogae	200918|Thermotogae	C	flavodoxin nitric oxide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
WZS3_k127_4587819_0	1304284.L21TH_1633	3.931e-186	591.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,36FHR@31979|Clostridiaceae	186801|Clostridia	C	acetyl-CoA hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
WZS3_k127_4587819_3	1033810.HLPCO_002056	1.16e-165	526.0	COG0332@1|root,COG0332@2|Bacteria,2NQSU@2323|unclassified Bacteria	2|Bacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WZS3_k127_4587819_1	1304284.L21TH_1621	3.296e-180	575.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
WZS3_k127_4587819_4	1511.CLOST_0928	2.763e-156	498.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,25QD2@186804|Peptostreptococcaceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS3_k127_4587819_2	1307761.L21SP2_1013	8.839e-166	526.0	COG0078@1|root,COG0078@2|Bacteria,2J5RT@203691|Spirochaetes	203691|Spirochaetes	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
WZS3_k127_4587819_6	1511.CLOST_0926	7.739e-71	242.0	COG2235@1|root,COG2235@2|Bacteria,1TQWS@1239|Firmicutes,249V9@186801|Clostridia,25SER@186804|Peptostreptococcaceae	186801|Clostridia	E	Amidinotransferase	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
WZS3_k127_4599090_0	720554.Clocl_1941	1.44e-208	669.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia,3WHSB@541000|Ruminococcaceae	186801|Clostridia	NT	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
WZS3_k127_4599090_1	1121324.CLIT_11c02130	6.651e-54	193.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
WZS3_k127_4611066_0	1121335.Clst_1662	1.217e-92	322.0	COG3858@1|root,COG3858@2|Bacteria,1U6TM@1239|Firmicutes,24B95@186801|Clostridia	186801|Clostridia	L	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,SLH
WZS3_k127_4611066_3	1122915.AUGY01000099_gene3660	8.322e-12	71.0	COG0454@1|root,COG0456@2|Bacteria,1VIPP@1239|Firmicutes,4HP67@91061|Bacilli,26Z38@186822|Paenibacillaceae	91061|Bacilli	K	GNAT family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
WZS3_k127_4611066_1	203119.Cthe_0398	4.214e-45	165.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24NFX@186801|Clostridia,3WK63@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WZS3_k127_4611066_2	1122216.AUHW01000038_gene263	3.067e-26	111.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4H4AN@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WZS3_k127_4632831_0	1121324.CLIT_10c01410	8.78e-72	255.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
WZS3_k127_4632831_1	1511.CLOST_0220	1.06e-26	118.0	COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,24HC0@186801|Clostridia,25T4Y@186804|Peptostreptococcaceae	186801|Clostridia	NOU	Bacterial Peptidase A24 N-terminal domain	hofD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
WZS3_k127_4632831_2	1291050.JAGE01000001_gene693	0.0001126	49.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25Q4H@186801|Clostridia,3WH43@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
WZS3_k127_4643290_0	1304284.L21TH_1736	1.56e-220	699.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E4P@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_4643290_1	1443125.Z962_07670	1.098e-56	219.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EQK@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
WZS3_k127_4646520_1	1128398.Curi_c06410	2.015e-47	188.0	COG2234@1|root,COG2234@2|Bacteria,1V13T@1239|Firmicutes,24A8F@186801|Clostridia	186801|Clostridia	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
WZS3_k127_4646520_0	1122947.FR7_3093	2.696e-110	365.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4H58U@909932|Negativicutes	909932|Negativicutes	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
WZS3_k127_4648149_0	1121396.KB892935_gene3829	3.631e-132	447.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9
WZS3_k127_4648149_1	1007103.AFHW01000164_gene3142	1.964e-24	114.0	COG4632@1|root,COG4632@2|Bacteria,1UIJE@1239|Firmicutes,4ISK3@91061|Bacilli,27757@186822|Paenibacillaceae	91061|Bacilli	G	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
WZS3_k127_4648149_2	649349.Lbys_1338	0.0001125	48.0	COG1961@1|root,COG1961@2|Bacteria,4NFJA@976|Bacteroidetes,47RIT@768503|Cytophagia	976|Bacteroidetes	L	Site-specific recombinase, DNA invertase Pin	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
WZS3_k127_4650827_0	1511.CLOST_1012	6.681e-159	511.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,2494X@186801|Clostridia,25R4W@186804|Peptostreptococcaceae	186801|Clostridia	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
WZS3_k127_4650827_1	1033810.HLPCO_001960	9.998e-32	126.0	2C1XY@1|root,32SVI@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4659473_0	1304284.L21TH_1542	5e-324	1004.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,36E0I@31979|Clostridiaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WZS3_k127_4661385_2	1408422.JHYF01000002_gene2301	1.131e-31	126.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,36H48@31979|Clostridiaceae	186801|Clostridia	K	response regulator, receiver	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS3_k127_4661385_0	1304284.L21TH_2163	2.112e-198	628.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,36F9C@31979|Clostridiaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
WZS3_k127_4661385_1	445972.ANACOL_00461	7.142e-82	278.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WGB8@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_4673248_2	1291050.JAGE01000002_gene3447	1.396e-18	85.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24BUT@186801|Clostridia,3WHTP@541000|Ruminococcaceae	186801|Clostridia	K	TipAS antibiotic-recognition domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
WZS3_k127_4673248_0	1347086.CCBA010000009_gene1405	5.591e-231	729.0	COG1164@1|root,COG1164@2|Bacteria,1TR7D@1239|Firmicutes,4HA0P@91061|Bacilli,1ZBBH@1386|Bacillus	91061|Bacilli	E	oligoendopeptidase F	pepF1_3	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
WZS3_k127_4673248_1	555079.Toce_1159	9.597e-21	92.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia,42G2A@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM MCP methyltransferase, CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
WZS3_k127_4683789_1	1216932.CM240_1587	2.206e-97	330.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,36E0M@31979|Clostridiaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WZS3_k127_4683789_0	386415.NT01CX_0963	1.569e-119	392.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,36DDG@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_4683789_2	1280689.AUJC01000010_gene1844	1.561e-19	93.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,36FU3@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
WZS3_k127_4718163_1	1128398.Curi_c19100	3.895e-63	229.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,268AV@186813|unclassified Clostridiales	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
WZS3_k127_4718163_2	1128398.Curi_c12520	4.792e-20	98.0	COG4478@1|root,COG4478@2|Bacteria,1VA1P@1239|Firmicutes,24N7Q@186801|Clostridia,26BKY@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
WZS3_k127_4718163_0	1304284.L21TH_2742	7.207e-75	263.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1TQX3@1239|Firmicutes,24A3W@186801|Clostridia,36FUZ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
WZS3_k127_4725428_1	1232453.BAIF02000123_gene194	5.719e-91	314.0	COG0027@1|root,COG0027@2|Bacteria,1V1P8@1239|Firmicutes,24Q62@186801|Clostridia	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,Dala_Dala_lig_C
WZS3_k127_4725428_2	517418.Ctha_2134	2.83e-55	205.0	COG0451@1|root,COG2232@1|root,COG0451@2|Bacteria,COG2232@2|Bacteria	2|Bacteria	V	ATP-grasp domain	-	-	1.1.1.271,5.1.3.2,6.3.5.5	ko:K01784,ko:K01955,ko:K02377	ko00051,ko00052,ko00240,ko00250,ko00520,ko01100,map00051,map00052,map00240,map00250,map00520,map01100	M00051,M00361,M00362,M00632	R00256,R00291,R00575,R01395,R02984,R05692,R10948,R10949	RC00002,RC00010,RC00043,RC00289,RC01014,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3,Epimerase
WZS3_k127_4725428_0	1121342.AUCO01000009_gene496	3.71e-132	427.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,36DUG@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
WZS3_k127_4729496_3	913865.DOT_4713	1.264e-58	206.0	COG0251@1|root,COG0251@2|Bacteria,1VVJ9@1239|Firmicutes,24G4V@186801|Clostridia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WZS3_k127_4729496_1	1196322.A370_02203	2.596e-63	223.0	COG2128@1|root,COG2128@2|Bacteria,1V55P@1239|Firmicutes,24HT6@186801|Clostridia,36RNR@31979|Clostridiaceae	186801|Clostridia	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
WZS3_k127_4729496_0	1120746.CCNL01000017_gene2395	6.839e-79	268.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS3_k127_4729496_2	1195236.CTER_4377	1.694e-60	220.0	COG4585@1|root,COG4585@2|Bacteria,1UUZ9@1239|Firmicutes,248T2@186801|Clostridia,3WHW7@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
WZS3_k127_4734849_0	1536773.R70331_21260	2.191e-263	824.0	COG0488@1|root,COG0488@2|Bacteria,1TSB8@1239|Firmicutes,4HV4R@91061|Bacilli,26R3A@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran
WZS3_k127_4748467_2	1236976.JCM16418_4884	1.059e-40	155.0	COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,4ISY0@91061|Bacilli,277PN@186822|Paenibacillaceae	91061|Bacilli	S	bacterial-type flagellum-dependent swarming motility	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4748467_5	509191.AEDB02000108_gene1635	1.161e-25	120.0	COG4585@1|root,COG4585@2|Bacteria,1UUZ9@1239|Firmicutes,248T2@186801|Clostridia,3WHW7@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
WZS3_k127_4748467_1	1304284.L21TH_2392	1.636e-65	230.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,36H48@31979|Clostridiaceae	186801|Clostridia	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
WZS3_k127_4748467_4	1304284.L21TH_2397	1.271e-29	130.0	2EP4I@1|root,33GR9@2|Bacteria,1VN5J@1239|Firmicutes,24VJD@186801|Clostridia,36T53@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4748467_0	1304284.L21TH_2398	4.88e-111	366.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,36DTX@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_4748467_3	1304284.L21TH_2399	2.766e-34	137.0	COG0842@1|root,COG0842@2|Bacteria,1UZ26@1239|Firmicutes,25B9V@186801|Clostridia,36K9Z@31979|Clostridiaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS3_k127_4754234_0	1408422.JHYF01000001_gene2978	3.945e-134	431.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,36FF4@31979|Clostridiaceae	186801|Clostridia	NU	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WZS3_k127_4754234_2	1195236.CTER_2993	9.131e-07	57.0	COG2882@1|root,COG2882@2|Bacteria,1VK96@1239|Firmicutes,24RWK@186801|Clostridia	186801|Clostridia	NOU	flagellar export protein FliJ	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
WZS3_k127_4754234_1	1304284.L21TH_2653	6.328e-46	181.0	28NKB@1|root,2ZBM6@2|Bacteria,1V3FB@1239|Firmicutes,24FZF@186801|Clostridia,36IGH@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4754685_0	1304284.L21TH_1603	3.736e-104	357.0	COG2206@1|root,COG3437@1|root,COG3850@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,COG3850@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia,36USS@31979|Clostridiaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
WZS3_k127_4754685_1	1304284.L21TH_0085	1.77e-42	164.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,36GX1@31979|Clostridiaceae	186801|Clostridia	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WZS3_k127_4754685_2	584708.Apau_2294	2.564e-17	82.0	COG0618@1|root,COG0618@2|Bacteria,3TBXW@508458|Synergistetes	508458|Synergistetes	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4770761_1	1128398.Curi_c20530	1.093e-82	277.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,26804@186813|unclassified Clostridiales	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WZS3_k127_4770761_0	1304284.L21TH_2464	2.483e-112	375.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,36DGU@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
WZS3_k127_4770761_2	632518.Calow_1544	1.192e-30	122.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,42FSF@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM Peptidase M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
WZS3_k127_4771035_1	1408422.JHYF01000010_gene3288	1.694e-137	451.0	COG3735@1|root,COG3735@2|Bacteria,1V7NU@1239|Firmicutes,24IJ8@186801|Clostridia,36GTV@31979|Clostridiaceae	186801|Clostridia	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
WZS3_k127_4771035_2	748727.CLJU_c36310	3.498e-16	84.0	COG2818@1|root,COG2818@2|Bacteria	2|Bacteria	L	DNA-3-methyladenine glycosylase activity	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
WZS3_k127_4771035_0	1304284.L21TH_1150	8.959e-145	469.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,36DNZ@31979|Clostridiaceae	186801|Clostridia	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_4771664_0	562743.JH976440_gene234	4.301e-104	342.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCEU@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_4771664_2	1511.CLOST_1320	3.199e-32	131.0	COG1846@1|root,COG1846@2|Bacteria,1VEFZ@1239|Firmicutes,24MSB@186801|Clostridia,25TFF@186804|Peptostreptococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_4771664_1	1511.CLOST_1319	6.676e-65	226.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	mepA1	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_4791065_1	536227.CcarbDRAFT_1806	1.245e-54	196.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,36EYP@31979|Clostridiaceae	186801|Clostridia	L	helicase	cshA2	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
WZS3_k127_4791065_0	946235.CAER01000074_gene579	4.626e-154	493.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,23K3F@182709|Oceanobacillus	91061|Bacilli	L	Bacterial DNA topoisomeraes I ATP-binding domain	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
WZS3_k127_4807042_1	1121289.JHVL01000002_gene2448	1.158e-44	177.0	COG5662@1|root,COG5662@2|Bacteria,1UHWV@1239|Firmicutes,24JF8@186801|Clostridia,36K4C@31979|Clostridiaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
WZS3_k127_4807042_2	1408422.JHYF01000002_gene2312	1.939e-35	144.0	COG2968@1|root,COG2968@2|Bacteria,1VB7C@1239|Firmicutes,24MYD@186801|Clostridia,36IF7@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
WZS3_k127_4807042_0	1120998.AUFC01000001_gene1998	1.524e-88	301.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WCFG@538999|Clostridiales incertae sedis	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
WZS3_k127_4821603_1	477974.Daud_0963	4.238e-07	58.0	2FGW6@1|root,348RG@2|Bacteria,1UJS6@1239|Firmicutes,25F8I@186801|Clostridia,263BT@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4821603_3	1408422.JHYF01000001_gene2807	1.363e-05	54.0	2E3CE@1|root,32YBQ@2|Bacteria,1VF4G@1239|Firmicutes	1239|Firmicutes	S	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WZS3_k127_4821603_2	477974.Daud_0963	9.259e-07	61.0	2FGW6@1|root,348RG@2|Bacteria,1UJS6@1239|Firmicutes,25F8I@186801|Clostridia,263BT@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4821603_0	452637.Oter_3065	2.209e-12	80.0	COG0823@1|root,COG3210@1|root,COG5276@1|root,COG0823@2|Bacteria,COG3210@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	U	domain, Protein	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3739,Germane,Gmad1,Haemagg_act,LVIVD
WZS3_k127_4821603_4	1280390.CBQR020000153_gene4169	8.631e-05	55.0	COG3867@1|root,COG5492@1|root,COG3867@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,4ITN2@91061|Bacilli	91061|Bacilli	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
WZS3_k127_4824953_4	1301100.HG529306_gene3151	6.561e-18	85.0	COG1670@1|root,COG1670@2|Bacteria,1V485@1239|Firmicutes,251F9@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_4824953_0	1121289.JHVL01000013_gene1673	1.264e-114	379.0	COG3191@1|root,COG3191@2|Bacteria,1TQHA@1239|Firmicutes,24CV6@186801|Clostridia,36F1R@31979|Clostridiaceae	186801|Clostridia	EQ	Peptidase family S58	dmpA	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
WZS3_k127_4824953_1	1195236.CTER_2278	2.475e-66	232.0	COG0491@1|root,COG0491@2|Bacteria,1VHN6@1239|Firmicutes,24AT7@186801|Clostridia	186801|Clostridia	S	Zn-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS3_k127_4824953_2	318464.IO99_03145	3.533e-43	162.0	COG1683@1|root,COG1683@2|Bacteria,1V700@1239|Firmicutes,24JD2@186801|Clostridia,36JUS@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
WZS3_k127_4824953_3	509191.AEDB02000094_gene4169	6.141e-42	157.0	COG1670@1|root,COG5646@1|root,COG1670@2|Bacteria,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,3WKGY@541000|Ruminococcaceae	186801|Clostridia	J	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
WZS3_k127_4824953_5	1408422.JHYF01000008_gene3615	2.679e-06	51.0	COG0226@1|root,COG0226@2|Bacteria,1VT8I@1239|Firmicutes,24IAW@186801|Clostridia	186801|Clostridia	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
WZS3_k127_4825715_5	1151292.QEW_2373	0.0008326	44.0	COG0316@1|root,COG0316@2|Bacteria,1VGGP@1239|Firmicutes,24HQ7@186801|Clostridia,25RV5@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
WZS3_k127_4825715_2	883114.HMPREF9709_00720	1.73e-162	534.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,22FY0@1570339|Peptoniphilaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,Big_2,CBM_20,CBM_48,PUD
WZS3_k127_4825715_0	1121324.CLIT_5c00480	1.684e-312	976.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25QJN@186804|Peptostreptococcaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
WZS3_k127_4825715_1	1304284.L21TH_1358	8.045e-169	543.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,36E5E@31979|Clostridiaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WZS3_k127_4825715_3	1121324.CLIT_5c00460	1.076e-114	381.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,25QUP@186804|Peptostreptococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WZS3_k127_4825715_4	883114.HMPREF9709_00716	2.814e-91	306.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,22H11@1570339|Peptoniphilaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WZS3_k127_483743_1	1449337.JQLL01000001_gene1220	8.335e-42	164.0	COG0477@1|root,COG2814@2|Bacteria,1UZ7N@1239|Firmicutes,4HIBQ@91061|Bacilli	91061|Bacilli	EGP	MFS_1 like family	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
WZS3_k127_483743_0	1286171.EAL2_c15700	1.281e-174	567.0	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,25WEQ@186806|Eubacteriaceae	186801|Clostridia	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
WZS3_k127_4847160_1	1123252.ATZF01000007_gene219	1.871e-40	152.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
WZS3_k127_4847160_2	324602.Caur_2511	1.982e-35	145.0	COG3231@1|root,COG3231@2|Bacteria	2|Bacteria	J	kanamycin kinase activity	ymdC	-	2.7.1.87,2.7.1.95	ko:K00897,ko:K10673,ko:K19272,ko:K19299,ko:K19300	-	M00766	-	-	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH
WZS3_k127_4847160_0	1123274.KB899420_gene4054	4.051e-52	195.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WZS3_k127_4850462_6	1280390.CBQR020000096_gene2156	5.703e-15	79.0	COG4635@1|root,COG4635@2|Bacteria,1VBP3@1239|Firmicutes,4HN76@91061|Bacilli,26X37@186822|Paenibacillaceae	91061|Bacilli	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
WZS3_k127_4850462_3	1122172.KB890260_gene1731	6.363e-46	177.0	COG0657@1|root,COG0657@2|Bacteria,37C7Z@32066|Fusobacteria	32066|Fusobacteria	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WZS3_k127_4850462_1	1408422.JHYF01000006_gene1154	6.762e-70	246.0	COG0778@1|root,COG0778@2|Bacteria,1V0NJ@1239|Firmicutes,24FM7@186801|Clostridia,36EJ6@31979|Clostridiaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase
WZS3_k127_4850462_2	536227.CcarbDRAFT_0107	9.373e-50	185.0	COG3647@1|root,COG3647@2|Bacteria,1V19Q@1239|Firmicutes,249U7@186801|Clostridia,36DSZ@31979|Clostridiaceae	186801|Clostridia	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
WZS3_k127_4850462_0	1449050.JNLE01000003_gene2678	3.104e-98	342.0	COG5263@1|root,COG5513@1|root,COG5263@2|Bacteria,COG5513@2|Bacteria,1TSIS@1239|Firmicutes,25EBW@186801|Clostridia,36UJT@31979|Clostridiaceae	186801|Clostridia	KLT	Protein of unknown function (DUF3298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,WG_beta_rep
WZS3_k127_4850462_4	1321778.HMPREF1982_03737	1.263e-40	153.0	COG0346@1|root,COG0346@2|Bacteria,1VY90@1239|Firmicutes,24Q48@186801|Clostridia	186801|Clostridia	E	Lactoylglutathione lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4850462_5	1121324.CLIT_13c01060	3.655e-37	142.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WZS3_k127_486881_0	1121324.CLIT_2c00460	1.841e-231	722.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25T57@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
WZS3_k127_486881_1	1511.CLOST_2151	2.295e-81	285.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25SUT@186804|Peptostreptococcaceae	186801|Clostridia	NT	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
WZS3_k127_4876275_0	1121289.JHVL01000010_gene1395	1.744e-177	569.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,36DBM@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
WZS3_k127_4876275_1	350688.Clos_2212	3.285e-105	351.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,36ERQ@31979|Clostridiaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
WZS3_k127_4876275_2	1128398.Curi_c05780	1.46e-77	272.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,267WM@186813|unclassified Clostridiales	186801|Clostridia	E	Aminotransferase class I and II	cobD2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15770	Aminotran_1_2
WZS3_k127_4878242_0	1218084.BBJK01000134_gene7205	1.009e-90	312.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,HAMP,PAS_3,PAS_4,PAS_9,Response_reg
WZS3_k127_4878242_2	1280692.AUJL01000031_gene1975	4.884e-53	200.0	COG2309@1|root,COG2309@2|Bacteria,1UMYG@1239|Firmicutes,24DHQ@186801|Clostridia	186801|Clostridia	E	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
WZS3_k127_4878242_1	742765.HMPREF9457_01946	1.419e-77	261.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,27V0U@189330|Dorea	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	bdhA	GO:0003674,GO:0003824,GO:0004022,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	-	ko:K00100,ko:K19955	ko00650,ko01120,map00650,map01120	-	R03544,R03545	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
WZS3_k127_4879925_1	350688.Clos_0071	3.831e-79	268.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,36EAN@31979|Clostridiaceae	186801|Clostridia	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
WZS3_k127_4879925_0	350688.Clos_0070	2.986e-271	845.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,36E27@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
WZS3_k127_4879925_2	1511.CLOST_1155	2.684e-14	73.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,25QX1@186804|Peptostreptococcaceae	186801|Clostridia	C	Phosphate acetyl/butaryl transferase	ptb1	-	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
WZS3_k127_4880325_3	1121422.AUMW01000006_gene684	1.485e-32	127.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,261P1@186807|Peptococcaceae	186801|Clostridia	K	PFAM Response regulator receiver domain	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_4880325_0	666686.B1NLA3E_02745	2.568e-100	343.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HAU7@91061|Bacilli,1ZB6A@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_4880325_1	1511.CLOST_1449	7.75e-99	325.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D,HTH_30
WZS3_k127_4880325_2	1123009.AUID01000003_gene1958	4.643e-92	304.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,26A3N@186813|unclassified Clostridiales	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	hgdB	-	-	-	-	-	-	-	-	-	-	-	HGD-D,HTH_30
WZS3_k127_4880325_4	1511.CLOST_1448	1.206e-25	108.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WZS3_k127_4902822_2	1391646.AVSU01000029_gene2643	3.508e-32	133.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,25QG9@186804|Peptostreptococcaceae	186801|Clostridia	H	coproporphyrinogen III oxidase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS3_k127_4902822_0	1304284.L21TH_1257	1.134e-63	225.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,36I3Z@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS3_k127_4902822_1	1035196.HMPREF9998_00293	9.71e-59	207.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,25TE8@186804|Peptostreptococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WZS3_k127_4902822_3	865861.AZSU01000003_gene1575	7.146e-06	49.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,36EH5@31979|Clostridiaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
WZS3_k127_4917578_3	445973.CLOBAR_02390	3.045e-36	139.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,25RBB@186804|Peptostreptococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WZS3_k127_4917578_2	1511.CLOST_2393	5.703e-79	270.0	COG0664@1|root,COG0664@2|Bacteria,1U9VC@1239|Firmicutes,25CK0@186801|Clostridia	186801|Clostridia	K	cyclic nucleotide-binding	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WZS3_k127_4917578_1	1511.CLOST_2392	4.534e-86	291.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,25QR5@186804|Peptostreptococcaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WZS3_k127_4917578_0	1511.CLOST_2391	2.898e-135	434.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25R2X@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
WZS3_k127_4930132_0	1340434.AXVA01000023_gene3359	1.978e-170	548.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,1ZB77@1386|Bacillus	91061|Bacilli	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	-	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS3_k127_4930132_2	865861.AZSU01000002_gene2501	1.06e-99	332.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,36EV6@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WZS3_k127_4930132_1	1321778.HMPREF1982_04262	1.599e-104	344.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,2688K@186813|unclassified Clostridiales	186801|Clostridia	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WZS3_k127_4942946_0	1519439.JPJG01000066_gene2382	3.248e-41	156.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,2N6GK@216572|Oscillospiraceae	186801|Clostridia	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS3_k127_4942946_2	588581.Cpap_3279	1.518e-24	105.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3WGHX@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS3_k127_4942946_1	871968.DESME_02060	1.295e-30	123.0	arCOG15062@1|root,32Y8D@2|Bacteria,1VEUQ@1239|Firmicutes,24TKJ@186801|Clostridia,262D1@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PQ-loop
WZS3_k127_4948723_0	1321778.HMPREF1982_02225	4.523e-171	551.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,268EB@186813|unclassified Clostridiales	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
WZS3_k127_4948723_1	1121335.Clst_0285	2.331e-71	245.0	COG2129@1|root,COG2129@2|Bacteria,1V0W0@1239|Firmicutes,24A73@186801|Clostridia,3WJ04@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
WZS3_k127_4956528_0	290402.Cbei_2737	1.174e-115	389.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,36F3M@31979|Clostridiaceae	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
WZS3_k127_4956528_1	536232.CLM_0750	3.628e-51	186.0	COG1633@1|root,COG1633@2|Bacteria,1V4P6@1239|Firmicutes,24IYH@186801|Clostridia,36J9Q@31979|Clostridiaceae	186801|Clostridia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WZS3_k127_4961450_0	1121324.CLIT_23c04210	1.601e-111	366.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,25R1C@186804|Peptostreptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WZS3_k127_4961450_2	1121936.AUHI01000004_gene1542	6.367e-23	102.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli	91061|Bacilli	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	ylxM	GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
WZS3_k127_4961450_1	1121289.JHVL01000003_gene2251	1.946e-74	252.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,36E8W@31979|Clostridiaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WZS3_k127_4965431_1	748727.CLJU_c12610	1.456e-44	168.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,36F03@31979|Clostridiaceae	186801|Clostridia	T	Phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
WZS3_k127_4965431_0	865861.AZSU01000003_gene1627	9.072e-107	363.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,36DBS@31979|Clostridiaceae	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WZS3_k127_4972367_2	941824.TCEL_00703	2.76e-47	173.0	COG2390@1|root,COG2390@2|Bacteria,1TP62@1239|Firmicutes,24B2X@186801|Clostridia,36DHS@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	cggR	-	-	ko:K05311	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
WZS3_k127_4972367_0	565034.BHWA1_01681	5.385e-176	557.0	COG0057@1|root,COG0057@2|Bacteria,2J5AD@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WZS3_k127_4972367_1	1415775.U729_339	1.166e-117	381.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,36ETN@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WZS3_k127_4979474_2	332101.JIBU02000004_gene146	1.527e-52	205.0	COG0840@1|root,COG0840@2|Bacteria,1U3C3@1239|Firmicutes,25AZR@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
WZS3_k127_4979474_1	580327.Tthe_1545	2.908e-70	242.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,42G0W@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
WZS3_k127_4979474_0	1280692.AUJL01000007_gene1343	2.955e-110	362.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,36EAK@31979|Clostridiaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_5034781_0	1163617.SCD_n01561	6.057e-260	820.0	28HY3@1|root,2Z83I@2|Bacteria,1R5P3@1224|Proteobacteria,2VZ4M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
WZS3_k127_5034781_1	1033743.CAES01000091_gene2796	4.205e-37	142.0	COG3877@1|root,COG3877@2|Bacteria,1VGSH@1239|Firmicutes,4HQ68@91061|Bacilli,27139@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
WZS3_k127_5041844_1	525256.HMPREF0091_10350	5.578e-32	129.0	COG3279@1|root,COG3279@2|Bacteria,2GX1S@201174|Actinobacteria	201174|Actinobacteria	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
WZS3_k127_5041844_0	457421.CBFG_05136	3.455e-49	187.0	COG2357@1|root,COG2357@2|Bacteria,1UFII@1239|Firmicutes,24GAE@186801|Clostridia	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
WZS3_k127_5043888_3	765912.Thimo_0609	2.993e-47	177.0	COG4245@1|root,COG4245@2|Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
WZS3_k127_5043888_4	696747.NIES39_P00090	8.296e-20	104.0	COG0631@1|root,COG0631@2|Bacteria,1G7U4@1117|Cyanobacteria,1HFNN@1150|Oscillatoriales	1117|Cyanobacteria	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
WZS3_k127_5043888_5	748449.Halha_1693	6.076e-17	86.0	COG1846@1|root,COG1846@2|Bacteria,1VFWY@1239|Firmicutes,25CQD@186801|Clostridia	186801|Clostridia	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_5043888_0	1304284.L21TH_0755	7.38e-178	565.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,36E9B@31979|Clostridiaceae	186801|Clostridia	E	aminopeptidase	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WZS3_k127_5043888_2	1408422.JHYF01000008_gene3573	1.241e-52	191.0	arCOG05203@1|root,32RHJ@2|Bacteria,1VBFD@1239|Firmicutes,24Q1N@186801|Clostridia,36JY2@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5043888_1	373903.Hore_05280	3.942e-127	424.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,3WAHI@53433|Halanaerobiales	186801|Clostridia	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WZS3_k127_5055885_1	293826.Amet_1491	1.355e-32	133.0	COG2311@1|root,COG2311@2|Bacteria,1TQNS@1239|Firmicutes,24XMI@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
WZS3_k127_5055885_3	762982.HMPREF9442_00983	4.605e-14	73.0	2EG1V@1|root,339TV@2|Bacteria,4NX9J@976|Bacteroidetes,2FUKH@200643|Bacteroidia	976|Bacteroidetes	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
WZS3_k127_5055885_0	1151292.QEW_1454	1.181e-167	535.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25R7H@186804|Peptostreptococcaceae	186801|Clostridia	I	Belongs to the thiolase family	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS3_k127_5055885_2	1385512.N784_04470	2.629e-31	123.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,2Y9NX@289201|Pontibacillus	91061|Bacilli	IQ	Short-chain dehydrogenase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS3_k127_5057314_1	1121289.JHVL01000008_gene1229	3.287e-37	151.0	COG3290@1|root,COG3290@2|Bacteria,1TQNZ@1239|Firmicutes,249FI@186801|Clostridia,36FVD@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	2.7.13.3	ko:K07717	ko02020,map02020	M00518	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
WZS3_k127_5057314_0	1123288.SOV_5c02730	5.173e-42	164.0	COG5482@1|root,COG5482@2|Bacteria,1V3FI@1239|Firmicutes,4H78S@909932|Negativicutes	909932|Negativicutes	S	Putative PD-(D/E)XK phosphodiesterase (DUF2161)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2161
WZS3_k127_5057314_2	189426.PODO_25500	1.156e-29	124.0	COG1670@1|root,COG1670@2|Bacteria,1V6M5@1239|Firmicutes,4HKBB@91061|Bacilli,26XDW@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_5057314_3	865861.AZSU01000001_gene367	2.856e-09	58.0	COG1633@1|root,COG1633@2|Bacteria,1V4P6@1239|Firmicutes,24IYH@186801|Clostridia,36J9Q@31979|Clostridiaceae	186801|Clostridia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WZS3_k127_5057597_2	1293054.HSACCH_02152	7.63e-63	228.0	COG1307@1|root,COG1461@1|root,COG1307@2|Bacteria,COG1461@2|Bacteria,1TR6J@1239|Firmicutes,24A8H@186801|Clostridia,3WC9D@53433|Halanaerobiales	186801|Clostridia	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
WZS3_k127_5057597_0	1511.CLOST_0666	1.7e-100	334.0	COG3752@1|root,COG3752@2|Bacteria,1V0FI@1239|Firmicutes,24GQX@186801|Clostridia	186801|Clostridia	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WZS3_k127_5057597_1	1121324.CLIT_13c01540	1.032e-69	247.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
WZS3_k127_5068450_1	1410668.JNKC01000022_gene2171	2.158e-121	395.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,36F05@31979|Clostridiaceae	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WZS3_k127_5068450_0	1120998.AUFC01000012_gene467	3.594e-145	468.0	COG0697@1|root,COG0697@2|Bacteria,1TPST@1239|Firmicutes,248K5@186801|Clostridia	186801|Clostridia	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_5068450_2	272562.CA_C0460	3.05e-19	89.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WZS3_k127_5076593_1	350688.Clos_2362	2.898e-82	282.0	COG3829@1|root,COG3829@2|Bacteria,1TP0E@1239|Firmicutes,247MB@186801|Clostridia,36DY7@31979|Clostridiaceae	186801|Clostridia	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PAS_9,Sigma54_activat
WZS3_k127_5076593_0	573061.Clocel_2521	3.3e-139	450.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia,36EBC@31979|Clostridiaceae	186801|Clostridia	V	PFAM peptidase U61, LD-carboxypeptidase A	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
WZS3_k127_5076593_4	138119.DSY1194	5.652e-36	144.0	COG1514@1|root,COG1514@2|Bacteria,1VEU2@1239|Firmicutes,24MTR@186801|Clostridia,262QN@186807|Peptococcaceae	186801|Clostridia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
WZS3_k127_5076593_2	1444309.JAQG01000084_gene3053	2.501e-68	241.0	COG0491@1|root,COG0491@2|Bacteria,1V0KE@1239|Firmicutes,4HEH9@91061|Bacilli,275BM@186822|Paenibacillaceae	91061|Bacilli	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS3_k127_5076593_3	1121472.AQWN01000004_gene672	3.333e-61	214.0	COG2606@1|root,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,24HH2@186801|Clostridia,261Y6@186807|Peptococcaceae	186801|Clostridia	S	PFAM YbaK prolyl-tRNA synthetases associated domain	EbsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
WZS3_k127_5076663_0	756499.Desde_1594	5.62e-131	433.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,26003@186807|Peptococcaceae	186801|Clostridia	L	Helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
WZS3_k127_5076663_2	1246484.D479_19438	1.54e-27	112.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli,3NFK7@45667|Halobacillus	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	XK27_00085	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
WZS3_k127_5076663_3	218284.CCDN010000002_gene2272	9.307e-27	115.0	2F3TG@1|root,33WJV@2|Bacteria,1VWIG@1239|Firmicutes,4HWKU@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5076663_1	1414720.CBYM010000022_gene2199	1.143e-38	145.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,36E7X@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS3_k127_5117085_2	83406.HDN1F_07790	3.611e-38	149.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,1J7E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
WZS3_k127_5117085_0	66692.ABC1715	1.782e-79	269.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,1ZBWK@1386|Bacillus	91061|Bacilli	P	radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WZS3_k127_5117085_1	1232453.BAIF02000033_gene2624	6.618e-62	214.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,26808@186813|unclassified Clostridiales	186801|Clostridia	L	Endonuclease/Exonuclease/phosphatase family	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WZS3_k127_5134809_4	357809.Cphy_0649	1.073e-60	213.0	COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes,24AMP@186801|Clostridia,21ZDF@1506553|Lachnoclostridium	186801|Clostridia	L	PFAM transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
WZS3_k127_5134809_2	1121324.CLIT_23c04440	8.758e-93	312.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,25QEE@186804|Peptostreptococcaceae	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
WZS3_k127_5134809_3	1408422.JHYF01000001_gene2970	1.57e-64	225.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,36DSI@31979|Clostridiaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WZS3_k127_5134809_0	398512.JQKC01000007_gene1153	1.299e-206	653.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WZS3_k127_5134809_5	1121342.AUCO01000001_gene2018	5.504e-56	206.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,36EJZ@31979|Clostridiaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
WZS3_k127_5134809_1	865861.AZSU01000003_gene1672	3.079e-97	332.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,36EFG@31979|Clostridiaceae	186801|Clostridia	O	magnesium chelatase	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
WZS3_k127_5138456_1	1286171.EAL2_c11570	3.092e-76	263.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,25VRW@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
WZS3_k127_5138456_0	1304284.L21TH_2122	8.317e-238	749.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,36DQF@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS3_k127_5138456_2	865861.AZSU01000005_gene878	3.468e-30	128.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,36EY8@31979|Clostridiaceae	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
WZS3_k127_5144241_0	1304284.L21TH_1194	3.899e-101	339.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,36EB1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
WZS3_k127_5144241_1	1304284.L21TH_1195	2.008e-95	327.0	COG0614@1|root,COG0614@2|Bacteria,1UNE3@1239|Firmicutes,24AKE@186801|Clostridia,36E8Z@31979|Clostridiaceae	186801|Clostridia	P	Periplasmic binding protein	yvrC	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
WZS3_k127_5145169_5	1304284.L21TH_1824	5.013e-18	83.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdh	GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS3_k127_5145169_1	865861.AZSU01000003_gene2171	2.614e-165	528.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,36DTC@31979|Clostridiaceae	186801|Clostridia	C	malic enzyme	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
WZS3_k127_5145169_0	1121324.CLIT_11c02810	1.122e-166	534.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,25R6P@186804|Peptostreptococcaceae	186801|Clostridia	P	Aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
WZS3_k127_5145169_2	1216932.CM240_1617	3.471e-125	420.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,36DW2@31979|Clostridiaceae	186801|Clostridia	C	Inorganic pyrophosphatase	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
WZS3_k127_5145169_3	698758.AXY_08500	4.075e-92	308.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli	91061|Bacilli	F	purine nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_5145169_4	1304284.L21TH_1508	1.879e-65	226.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,36DSJ@31979|Clostridiaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
WZS3_k127_5150015_3	702450.CUW_0025	3.625e-08	54.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,3VQSQ@526524|Erysipelotrichia	526524|Erysipelotrichia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_5150015_0	1209989.TepiRe1_2199	6.214e-112	377.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,25EVD@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_5150015_1	1511.CLOST_0978	6.413e-83	278.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,25TFP@186804|Peptostreptococcaceae	186801|Clostridia	O	Belongs to the glutathione peroxidase family	gpo	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WZS3_k127_5150015_2	1031288.AXAA01000009_gene734	2.371e-40	157.0	COG5012@1|root,COG5012@2|Bacteria,1V5EH@1239|Firmicutes,24HIB@186801|Clostridia,36J2Q@31979|Clostridiaceae	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
WZS3_k127_5158497_2	1511.CLOST_2382	1.891e-30	121.0	COG1776@1|root,COG1776@2|Bacteria,1V9D5@1239|Firmicutes,24GE0@186801|Clostridia	186801|Clostridia	NT	Chemotaxis protein CheC, inhibitor of MCP methylation	-	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
WZS3_k127_5158497_1	1511.CLOST_2383	1.079e-89	305.0	COG2199@1|root,COG2199@2|Bacteria,1V2A9@1239|Firmicutes,2489K@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS
WZS3_k127_5158497_3	335541.Swol_1734	1.112e-11	74.0	COG2834@1|root,COG2834@2|Bacteria,1TV4Q@1239|Firmicutes,259FI@186801|Clostridia,42KRH@68298|Syntrophomonadaceae	186801|Clostridia	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5158497_0	1033810.HLPCO_002767	1.101e-246	773.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
WZS3_k127_5163585_0	350688.Clos_0860	9.836e-129	427.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,36DXC@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
WZS3_k127_5163585_1	632245.CLP_3233	4.228e-66	230.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,36FG9@31979|Clostridiaceae	186801|Clostridia	KT	transcriptional regulatory protein	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_517057_0	350688.Clos_1779	2.403e-100	333.0	COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
WZS3_k127_517057_1	1304284.L21TH_1293	1.58e-91	306.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,36E08@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WZS3_k127_517057_2	1235800.C819_03880	1.327e-46	179.0	COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,24GMY@186801|Clostridia,27NX2@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WZS3_k127_517057_3	1414720.CBYM010000012_gene2559	9.649e-42	164.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,36E26@31979|Clostridiaceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	fliB	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
WZS3_k127_5171196_0	350688.Clos_0663	8.443e-193	609.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,36E9B@31979|Clostridiaceae	186801|Clostridia	E	aminopeptidase	pepS	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
WZS3_k127_5171196_1	318464.IO99_08090	1.834e-85	284.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,36DRC@31979|Clostridiaceae	186801|Clostridia	C	FAD linked oxidase domain protein	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
WZS3_k127_5174665_1	350688.Clos_2716	1.818e-23	103.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia	186801|Clostridia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DsbD,Redoxin
WZS3_k127_5174665_0	642492.Clole_3075	2.571e-147	476.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WZS3_k127_5174665_2	1308866.J416_00324	2.28e-06	51.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,470K0@74385|Gracilibacillus	91061|Bacilli	S	Uncharacterised protein, DegV family COG1307	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_5187308_0	1280692.AUJL01000001_gene36	1.982e-37	162.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,24CZV@186801|Clostridia,36G8F@31979|Clostridiaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
WZS3_k127_5187308_1	580327.Tthe_0481	3.577e-20	101.0	COG1721@1|root,COG1721@2|Bacteria,1VA48@1239|Firmicutes,24E5S@186801|Clostridia,42G7S@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
WZS3_k127_5198704_1	1304284.L21TH_2557	7.193e-71	244.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,36E5Z@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WZS3_k127_5198704_0	1226325.HMPREF1548_00021	9.568e-272	849.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,36DYE@31979|Clostridiaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WZS3_k127_5198704_2	1128398.Curi_c00040	1.889e-37	144.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,268Q0@186813|unclassified Clostridiales	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WZS3_k127_5201701_3	1408823.AXUS01000003_gene556	2.103e-27	121.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,25RID@186804|Peptostreptococcaceae	186801|Clostridia	J	RNA-binding protein, YhbY family	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
WZS3_k127_5201701_0	1219626.HMPREF1639_03780	2.466e-167	535.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25QXG@186804|Peptostreptococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
WZS3_k127_5201701_1	1300150.EMQU_0826	5.243e-40	150.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli,4B2XW@81852|Enterococcaceae	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WZS3_k127_5201701_5	864565.HMPREF0379_0936	2.336e-13	74.0	COG2868@1|root,COG2868@2|Bacteria,1UEZU@1239|Firmicutes,25JZZ@186801|Clostridia,25U5K@186804|Peptostreptococcaceae	186801|Clostridia	J	Pfam:Peptidase_C108	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
WZS3_k127_5201701_2	699246.HMPREF0868_0688	4.419e-32	127.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WZS3_k127_5201701_4	1460640.JCM19046_4366	9.383e-20	98.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,4HC3Q@91061|Bacilli,1ZCCF@1386|Bacillus	91061|Bacilli	J	ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
WZS3_k127_5204563_1	1345695.CLSA_c08530	7.538e-123	406.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,36DF7@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WZS3_k127_5204563_0	858215.Thexy_0567	9.061e-130	433.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,42HSX@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Galactose-1-phosphate uridyl transferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
WZS3_k127_5212038_1	1120746.CCNL01000011_gene1768	5.499e-72	244.0	COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WZS3_k127_5212038_0	1304284.L21TH_1543	1.897e-271	846.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,36DSR@31979|Clostridiaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WZS3_k127_5216916_5	314724.BT0239	2.441e-22	101.0	COG1428@1|root,COG1428@2|Bacteria,2JAVV@203691|Spirochaetes	203691|Spirochaetes	F	Deoxynucleoside kinase	dck	-	2.7.1.74	ko:K00893	ko00230,ko00240,ko01100,map00230,map00240,map01100	-	R00185,R01666	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
WZS3_k127_5216916_6	1304284.L21TH_2002	1.861e-09	58.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,36EFA@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WZS3_k127_5216916_3	314724.BT0239	1.793e-43	167.0	COG1428@1|root,COG1428@2|Bacteria,2JAVV@203691|Spirochaetes	203691|Spirochaetes	F	Deoxynucleoside kinase	dck	-	2.7.1.74	ko:K00893	ko00230,ko00240,ko01100,map00230,map00240,map01100	-	R00185,R01666	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	dNK
WZS3_k127_5216916_0	1128398.Curi_c13320	6.894e-142	458.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,2687M@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WZS3_k127_5216916_1	1408422.JHYF01000001_gene2761	1.704e-83	291.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,36DXY@31979|Clostridiaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS3_k127_5216916_4	748727.CLJU_c29670	2.894e-38	158.0	2AM2W@1|root,31BWX@2|Bacteria,1V84G@1239|Firmicutes,24DXG@186801|Clostridia,36EZY@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	Glucosaminidase
WZS3_k127_5216916_2	1408422.JHYF01000002_gene2228	5.922e-83	283.0	COG1284@1|root,COG1284@2|Bacteria,1V5VT@1239|Firmicutes,24B0V@186801|Clostridia,36VMM@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WZS3_k127_5244025_1	1480694.DC28_01460	1.16e-31	129.0	COG0842@1|root,COG0842@2|Bacteria,2J72M@203691|Spirochaetes	203691|Spirochaetes	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS3_k127_5244025_0	1120746.CCNL01000017_gene2393	4.121e-156	496.0	COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WZS3_k127_5247250_5	1200792.AKYF01000003_gene266	6.745e-46	171.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli,26SG9@186822|Paenibacillaceae	91061|Bacilli	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
WZS3_k127_5247250_1	293826.Amet_0111	1.322e-93	313.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,36EDX@31979|Clostridiaceae	186801|Clostridia	L	Hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WZS3_k127_5247250_3	293826.Amet_0137	4.062e-58	207.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,24I8W@186801|Clostridia,36I6Z@31979|Clostridiaceae	186801|Clostridia	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step	rnmV	-	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
WZS3_k127_5247250_0	1121324.CLIT_24c00130	3.793e-95	320.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,25R4Y@186804|Peptostreptococcaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WZS3_k127_5247250_4	935845.JADQ01000007_gene1658	7.858e-56	202.0	COG1670@1|root,COG1670@2|Bacteria,1V1ZC@1239|Firmicutes,4HIDR@91061|Bacilli,274T4@186822|Paenibacillaceae	91061|Bacilli	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WZS3_k127_5247250_2	1304284.L21TH_1389	2.918e-73	263.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia,36ECN@31979|Clostridiaceae	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
WZS3_k127_5247250_6	431943.CKL_0758	5.717e-35	134.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,36DGG@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WZS3_k127_5252959_1	555079.Toce_1528	6.379e-63	229.0	COG0793@1|root,COG3409@1|root,COG0793@2|Bacteria,COG3409@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,42F0U@68295|Thermoanaerobacterales	186801|Clostridia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,PG_binding_1,Peptidase_S41
WZS3_k127_5252959_2	1304284.L21TH_2309	3.841e-20	94.0	COG2172@1|root,COG2172@2|Bacteria,1VFTW@1239|Firmicutes,24RBU@186801|Clostridia,36MVU@31979|Clostridiaceae	186801|Clostridia	T	sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5252959_0	357809.Cphy_1504	2.162e-142	462.0	2DB7K@1|root,2Z7MK@2|Bacteria,1TQ79@1239|Firmicutes,2489P@186801|Clostridia,21YG7@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF1576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1576
WZS3_k127_5254178_2	1280.SAXN108_2770	2.507e-20	94.0	COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,4HNR2@91061|Bacilli,4GZJA@90964|Staphylococcaceae	91061|Bacilli	S	GCN5-related N-acetyl-transferase	yjdJ	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
WZS3_k127_5254178_0	768706.Desor_4090	5.942e-30	130.0	COG0845@1|root,COG0845@2|Bacteria,1V3TH@1239|Firmicutes,24AAF@186801|Clostridia,263XA@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WZS3_k127_5254178_1	646529.Desaci_2841	3.407e-26	111.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,2641K@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG2	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WZS3_k127_5259687_0	459349.CLOAM1530	3.252e-163	523.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12,1.2.1.59,1.4.1.16	ko:K00134,ko:K00150,ko:K03340	ko00010,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00526,M00552	R01061,R01063,R02755	RC00006,RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	DapB_N,Gp_dh_C,Gp_dh_N
WZS3_k127_5259687_1	931626.Awo_c32170	5.66e-28	114.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,25ZUT@186806|Eubacteriaceae	186801|Clostridia	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WZS3_k127_5260894_0	1128398.Curi_c22910	5.903e-216	684.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,268JV@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
WZS3_k127_5260894_1	649639.Bcell_0912	1.213e-73	256.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4HA14@91061|Bacilli,1ZAV9@1386|Bacillus	91061|Bacilli	C	NADH dehydrogenase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DoxX,Pyr_redox_2
WZS3_k127_52830_1	1304284.L21TH_2683	5.439e-161	524.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,36F97@31979|Clostridiaceae	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WZS3_k127_52830_2	1128398.Curi_c12070	1.195e-56	212.0	2DKA9@1|root,32UEQ@2|Bacteria,1VE7Y@1239|Firmicutes,24KB2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_52830_0	1408422.JHYF01000011_gene3499	1.765e-207	651.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,36DDF@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WZS3_k127_5302044_0	1511.CLOST_1138	8.546e-61	232.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25SUT@186804|Peptostreptococcaceae	186801|Clostridia	NT	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,dCache_3
WZS3_k127_5334301_0	1304284.L21TH_0268	1.464e-91	318.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
WZS3_k127_5356819_6	1292035.H476_2516	7.15e-52	186.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,25SZB@186804|Peptostreptococcaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
WZS3_k127_5356819_4	1321778.HMPREF1982_03040	6.095e-85	302.0	28HMX@1|root,2Z7WB@2|Bacteria,1TPJG@1239|Firmicutes,24AWI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5356819_1	1408422.JHYF01000004_gene1666	1.074e-100	334.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia,36DUF@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_5356819_3	1286171.EAL2_c18640	2.344e-87	292.0	COG1584@1|root,COG1584@2|Bacteria,1TSYX@1239|Firmicutes,249E0@186801|Clostridia	186801|Clostridia	S	GPR1 FUN34 yaaH family	yaaH	-	-	ko:K07034	-	-	-	-	ko00000	-	-	-	Grp1_Fun34_YaaH
WZS3_k127_5356819_2	293826.Amet_1228	2.449e-92	311.0	COG0560@1|root,COG0560@2|Bacteria,1UYZ6@1239|Firmicutes,24AC7@186801|Clostridia,36EAG@31979|Clostridiaceae	186801|Clostridia	E	HAD-superfamily subfamily IB hydrolase	serB	-	-	-	-	-	-	-	-	-	-	-	HAD
WZS3_k127_5356819_0	1123009.AUID01000019_gene216	8.632e-109	358.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,269N4@186813|unclassified Clostridiales	186801|Clostridia	S	Carbon-nitrogen hydrolase	nit	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
WZS3_k127_5356819_7	931626.Awo_c35350	2.608e-32	133.0	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes,24IAS@186801|Clostridia,25XZ0@186806|Eubacteriaceae	186801|Clostridia	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WZS3_k127_5356819_5	1349822.NSB1T_05875	1.887e-63	226.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,2FNAK@200643|Bacteroidia,22X9F@171551|Porphyromonadaceae	976|Bacteroidetes	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
WZS3_k127_5377713_1	580331.Thit_1290	7.864e-73	257.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,42FM1@68295|Thermoanaerobacterales	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
WZS3_k127_5377713_0	1408422.JHYF01000001_gene2935	2.596e-176	559.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,36EE0@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
WZS3_k127_5379731_5	997350.HMPREF9129_1984	8.338e-16	83.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,22J70@1570339|Peptoniphilaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5379731_4	642492.Clole_1579	1.587e-21	96.0	COG1905@1|root,COG1905@2|Bacteria,1VFEK@1239|Firmicutes,24QMM@186801|Clostridia	186801|Clostridia	C	NADH ubiquinone oxidoreductase 24 kD subunit	fhmD	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
WZS3_k127_5379731_1	1121289.JHVL01000014_gene1815	3.504e-156	511.0	COG1145@1|root,COG4624@1|root,COG1145@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,24BF5@186801|Clostridia,36E2Y@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_7,PAS
WZS3_k127_5379731_2	1304284.L21TH_0543	4.662e-126	414.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,36FUJ@31979|Clostridiaceae	186801|Clostridia	KT	stage II sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
WZS3_k127_5379731_0	1121289.JHVL01000014_gene1817	3.34e-170	547.0	COG1142@1|root,COG4624@1|root,COG1142@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,36E6A@31979|Clostridiaceae	186801|Clostridia	C	-hydrogenase	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4
WZS3_k127_5379731_3	1196323.ALKF01000147_gene1293	1.197e-89	301.0	COG1351@1|root,COG1351@2|Bacteria,1TRHD@1239|Firmicutes,4HTFB@91061|Bacilli,26S56@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
WZS3_k127_5396981_1	642492.Clole_2678	3.702e-10	67.0	2DN90@1|root,32W6G@2|Bacteria,1VC37@1239|Firmicutes,24KFW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5396981_0	1151292.QEW_3905	0.0	1107.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25QNK@186804|Peptostreptococcaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WZS3_k127_5403030_3	485916.Dtox_1566	8.379e-46	168.0	COG1266@1|root,COG1266@2|Bacteria,1VWV1@1239|Firmicutes	1239|Firmicutes	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WZS3_k127_5403030_4	1408473.JHXO01000004_gene264	9.659e-42	159.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
WZS3_k127_5403030_1	1286093.C266_21514	2.218e-94	315.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,1K088@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
WZS3_k127_5403030_2	332101.JIBU02000079_gene3892	1.192e-88	297.0	COG0765@1|root,COG0765@2|Bacteria,1TPQ8@1239|Firmicutes,24BX1@186801|Clostridia,36FAP@31979|Clostridiaceae	186801|Clostridia	E	acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine	-	-	-	ko:K10009	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
WZS3_k127_5403030_0	1487921.DP68_03385	1.405e-98	330.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,36DVN@31979|Clostridiaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030,ko:K02424	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
WZS3_k127_5403030_5	931626.Awo_c33080	2.917e-17	83.0	COG3588@1|root,COG3588@2|Bacteria,1TPUJ@1239|Firmicutes,24924@186801|Clostridia,25US2@186806|Eubacteriaceae	186801|Clostridia	G	Fructose-bisphosphate aldolase class-I	fda	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
WZS3_k127_5420067_1	1408422.JHYF01000002_gene2293	7.163e-160	511.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,36DCC@31979|Clostridiaceae	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
WZS3_k127_5420067_0	1121289.JHVL01000004_gene2141	1.077e-274	856.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,36DJY@31979|Clostridiaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
WZS3_k127_5420626_0	1121289.JHVL01000005_gene1031	2.78e-207	654.0	COG0849@1|root,COG0849@2|Bacteria,1TQC5@1239|Firmicutes,24BFJ@186801|Clostridia,36ER4@31979|Clostridiaceae	186801|Clostridia	D	MutL protein	-	-	-	-	-	-	-	-	-	-	-	-	MutL
WZS3_k127_5420626_1	941824.TCEL_00353	4.435e-115	380.0	COG3457@1|root,COG3457@2|Bacteria,1TNYJ@1239|Firmicutes,248MC@186801|Clostridia,36ESB@31979|Clostridiaceae	186801|Clostridia	E	Alanine racemase, N-terminal domain	-	-	5.1.1.12	ko:K21898	ko00472,map00472	-	R00672	RC00302	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N
WZS3_k127_5420626_2	632292.Calhy_0652	5.303e-64	230.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1UDQ5@1239|Firmicutes,25AZX@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
WZS3_k127_5467271_0	1347392.CCEZ01000026_gene2997	5.505e-109	369.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,36EQ3@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_5467271_1	1410653.JHVC01000009_gene2804	7.818e-38	154.0	COG3276@1|root,COG3276@2|Bacteria,1TPQS@1239|Firmicutes,2484U@186801|Clostridia,36E0X@31979|Clostridiaceae	186801|Clostridia	J	translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
WZS3_k127_5468393_1	1121324.CLIT_4c01610	1.31e-148	476.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,25QDR@186804|Peptostreptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440,ko:K17214	ko02010,map02010	M00212,M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
WZS3_k127_5468393_0	1121324.CLIT_4c01620	5.274e-230	721.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,25SPP@186804|Peptostreptococcaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K17215	ko02010,map02010	M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2	-	-	ABC_tran
WZS3_k127_5468393_2	1121324.CLIT_4c01650	3.147e-124	416.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
WZS3_k127_5468393_3	318464.IO99_04255	1.83e-21	97.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,36EDH@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
WZS3_k127_5478772_3	1195236.CTER_2238	4.844e-16	79.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
WZS3_k127_5478772_1	293826.Amet_2991	1.326e-35	145.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,36FNA@31979|Clostridiaceae	186801|Clostridia	S	SAM-dependent methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
WZS3_k127_5478772_0	1408422.JHYF01000002_gene2472	1.973e-165	529.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,36E45@31979|Clostridiaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS3_k127_5478772_2	1301100.HG529352_gene4261	1.904e-25	117.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,36FK8@31979|Clostridiaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WZS3_k127_5486007_7	445973.CLOBAR_02179	9.965e-64	222.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,25QRX@186804|Peptostreptococcaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
WZS3_k127_5486007_4	1121289.JHVL01000005_gene1000	1.532e-79	276.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,36FDF@31979|Clostridiaceae	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WZS3_k127_5486007_9	1128398.Curi_c13450	4.322e-59	211.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,269G3@186813|unclassified Clostridiales	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
WZS3_k127_5486007_0	500633.CLOHIR_01161	4.993e-180	571.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,25QJC@186804|Peptostreptococcaceae	186801|Clostridia	O	Peptidase, U32 family	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
WZS3_k127_5486007_2	1121289.JHVL01000005_gene997	4.67e-97	320.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia,36DNP@31979|Clostridiaceae	186801|Clostridia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WZS3_k127_5486007_10	865861.AZSU01000001_gene342	6.181e-58	205.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,36IPD@31979|Clostridiaceae	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	2.7.1.24,4.2.3.3	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	M00120	R00130,R01016	RC00002,RC00078,RC00424	ko00000,ko00001,ko00002,ko01000	-	-	-	MGS
WZS3_k127_5486007_6	580331.Thit_1057	1.47e-71	254.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS3_k127_5486007_12	273068.TTE1275	1.744e-35	140.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,42GWP@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
WZS3_k127_5486007_3	350688.Clos_1624	9.554e-91	301.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,36DS4@31979|Clostridiaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WZS3_k127_5486007_13	1292035.H476_1965	2.177e-31	128.0	2E3FE@1|root,32YE8@2|Bacteria,1VFR0@1239|Firmicutes,24MNV@186801|Clostridia,25UJX@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5486007_15	546269.HMPREF0389_00708	8.114e-26	111.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,25RIH@186804|Peptostreptococcaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
WZS3_k127_5486007_14	1414720.CBYM010000008_gene1030	3.042e-27	115.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,36KIR@31979|Clostridiaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
WZS3_k127_5486007_8	865861.AZSU01000003_gene1821	1.204e-61	224.0	COG0533@1|root,COG0533@2|Bacteria,1TRPY@1239|Firmicutes,24CN4@186801|Clostridia,36IKM@31979|Clostridiaceae	186801|Clostridia	O	Glycoprotease family	gcp1	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WZS3_k127_5486007_1	857293.CAAU_2504	2.735e-105	355.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,36EU5@31979|Clostridiaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WZS3_k127_5486007_16	1297617.JPJD01000009_gene2917	1.042e-08	58.0	COG1722@1|root,COG1722@2|Bacteria,1VFJS@1239|Firmicutes,25IUP@186801|Clostridia,269QV@186813|unclassified Clostridiales	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WZS3_k127_5486007_5	272563.CD630_12050	1.786e-75	264.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,25QKP@186804|Peptostreptococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WZS3_k127_5486007_11	1511.CLOST_1344	1.004e-41	157.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,24MV7@186801|Clostridia,25RHI@186804|Peptostreptococcaceae	186801|Clostridia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
WZS3_k127_5501731_1	1304284.L21TH_1664	2.094e-54	200.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EVU@31979|Clostridiaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_2
WZS3_k127_5501731_2	1304284.L21TH_2069	5.46e-22	102.0	COG1308@1|root,COG1308@2|Bacteria,1V7I9@1239|Firmicutes,24M6Q@186801|Clostridia,36JCP@31979|Clostridiaceae	186801|Clostridia	K	UBA TS-N domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
WZS3_k127_5501731_0	1121324.CLIT_2c02560	8.49e-199	622.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,25T0P@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
WZS3_k127_5506041_8	1120973.AQXL01000033_gene2663	4.235e-08	62.0	COG0103@1|root,COG0103@2|Bacteria,1VAS8@1239|Firmicutes	1239|Firmicutes	J	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
WZS3_k127_5506041_7	868595.Desca_2650	2.904e-27	111.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,262CR@186807|Peptococcaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WZS3_k127_5506041_4	536227.CcarbDRAFT_2765	3.116e-90	300.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,36DU8@31979|Clostridiaceae	186801|Clostridia	F	thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WZS3_k127_5506041_1	1408422.JHYF01000012_gene3232	1.976e-96	324.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,36FM3@31979|Clostridiaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
WZS3_k127_5506041_5	1408422.JHYF01000012_gene3233	1.387e-56	208.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,36EJF@31979|Clostridiaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
WZS3_k127_5506041_0	500633.CLOHIR_01667	1.289e-148	477.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,25QD5@186804|Peptostreptococcaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WZS3_k127_5506041_2	246969.TAM4_157	3.239e-93	318.0	COG0009@1|root,arCOG01952@2157|Archaea,2XVGC@28890|Euryarchaeota,243AA@183968|Thermococci	183968|Thermococci	J	required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WZS3_k127_5506041_6	1035196.HMPREF9998_01498	3.078e-53	190.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,25RC3@186804|Peptostreptococcaceae	186801|Clostridia	G	isomerase B	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WZS3_k127_5506041_3	350688.Clos_2572	3.674e-91	302.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,36DZ9@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
WZS3_k127_5508826_1	37659.JNLN01000001_gene1301	1.151e-39	150.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,36EEA@31979|Clostridiaceae	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	-	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS3_k127_5508826_0	1123009.AUID01000005_gene1586	5.834e-201	638.0	COG1304@1|root,COG1304@2|Bacteria,1TPC5@1239|Firmicutes,247PK@186801|Clostridia,26AHZ@186813|unclassified Clostridiales	186801|Clostridia	C	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
WZS3_k127_5520218_1	1123009.AUID01000025_gene97	6.262e-144	469.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,26A2B@186813|unclassified Clostridiales	186801|Clostridia	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
WZS3_k127_5520218_0	744872.Spica_2337	1.059e-154	524.0	COG2199@1|root,COG3292@1|root,COG3292@2|Bacteria,COG3706@2|Bacteria,2J5A2@203691|Spirochaetes	203691|Spirochaetes	T	Diguanylate cyclase (GGDEF) domain	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,Reg_prop,Y_Y_Y
WZS3_k127_5530078_0	350688.Clos_1480	2.006e-91	304.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia,36E58@31979|Clostridiaceae	186801|Clostridia	N	flagellar motor switch protein FliG	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
WZS3_k127_5530078_1	350688.Clos_1479	9.153e-74	267.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,2498Q@186801|Clostridia,36FDA@31979|Clostridiaceae	186801|Clostridia	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
WZS3_k127_5530078_3	1121335.Clst_0535	2.43e-08	59.0	COG1677@1|root,COG1677@2|Bacteria,1VEEY@1239|Firmicutes,24R4F@186801|Clostridia	186801|Clostridia	N	PFAM flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
WZS3_k127_5530078_2	1291050.JAGE01000001_gene204	5.015e-37	141.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia,3WK29@541000|Ruminococcaceae	186801|Clostridia	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WZS3_k127_5539663_0	1499683.CCFF01000014_gene4046	8.85e-137	446.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,36FC0@31979|Clostridiaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
WZS3_k127_5539663_1	865861.AZSU01000001_gene428	3.569e-39	153.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,36M9G@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
WZS3_k127_5539663_2	986075.CathTA2_0111	1.004e-27	115.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli	91061|Bacilli	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WZS3_k127_5606448_1	350688.Clos_1764	3.054e-60	219.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,36EKP@31979|Clostridiaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WZS3_k127_5606448_2	1128398.Curi_c10090	6.766e-14	78.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,269U7@186813|unclassified Clostridiales	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
WZS3_k127_5606448_0	1286171.EAL2_c11530	6.214e-79	279.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,25VGU@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
WZS3_k127_5622123_1	865861.AZSU01000002_gene2366	1.92e-05	56.0	2BA2F@1|root,323G7@2|Bacteria,1UPZV@1239|Firmicutes,257M9@186801|Clostridia,36NJK@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5622123_0	386415.NT01CX_2091	3.083e-139	452.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,36E5D@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
WZS3_k127_5622123_2	1174504.AJTN02000241_gene4328	0.0004861	48.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,4HBT1@91061|Bacilli,1ZCZQ@1386|Bacillus	91061|Bacilli	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
WZS3_k127_5625968_2	1121289.JHVL01000008_gene1240	2.531e-99	327.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,36DRC@31979|Clostridiaceae	186801|Clostridia	C	FAD linked oxidase domain protein	glcD1	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
WZS3_k127_5625968_0	1304284.L21TH_1081	3.363e-175	556.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfA2	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
WZS3_k127_5625968_1	1410653.JHVC01000001_gene1687	3.532e-116	380.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36FGA@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfB1	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WZS3_k127_5625968_3	1121289.JHVL01000008_gene1234	9.907e-58	208.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,36F6A@31979|Clostridiaceae	186801|Clostridia	K	GntR domain protein	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
WZS3_k127_5628551_2	639282.DEFDS_2033	1.514e-13	75.0	COG3210@1|root,COG3591@1|root,COG5513@1|root,COG3210@2|Bacteria,COG3591@2|Bacteria,COG5513@2|Bacteria	2|Bacteria	G	serine-type aminopeptidase activity	-	-	-	ko:K02030,ko:K14475	ko05143,map05143	M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	Inhibitor_I42
WZS3_k127_5628551_0	1453498.LG45_08415	2.994e-82	280.0	COG1187@1|root,COG1187@2|Bacteria,4NFE1@976|Bacteroidetes,1HY0B@117743|Flavobacteriia,2NSW8@237|Flavobacterium	976|Bacteroidetes	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_5628551_1	1110502.TMO_2866	5.99e-66	232.0	COG0583@1|root,COG0583@2|Bacteria,1PMTG@1224|Proteobacteria,2TV35@28211|Alphaproteobacteria,2JPYD@204441|Rhodospirillales	204441|Rhodospirillales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WZS3_k127_5632139_3	1298920.KI911353_gene2539	9.728e-05	45.0	COG1319@1|root,COG1319@2|Bacteria,1TRPF@1239|Firmicutes,24C3J@186801|Clostridia,2206T@1506553|Lachnoclostridium	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_5
WZS3_k127_5632139_0	796606.BMMGA3_09550	1.709e-241	769.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,4HC1W@91061|Bacilli,1ZC08@1386|Bacillus	91061|Bacilli	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
WZS3_k127_5632139_1	1294142.CINTURNW_2380	1.489e-57	219.0	COG0840@1|root,COG0840@2|Bacteria,1UV9Z@1239|Firmicutes,24DK9@186801|Clostridia,36FEJ@31979|Clostridiaceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
WZS3_k127_5632139_2	1232443.BAIA02000071_gene555	5.46e-06	48.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,2689E@186813|unclassified Clostridiales	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
WZS3_k127_5636588_0	1408422.JHYF01000003_gene927	0.0	1202.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,36DHP@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WZS3_k127_5636588_1	1121914.AUDW01000003_gene1121	1.231e-39	157.0	COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,4HAW1@91061|Bacilli,3WF75@539002|Bacillales incertae sedis	91061|Bacilli	S	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
WZS3_k127_5641495_2	1121289.JHVL01000041_gene3048	4.167e-16	84.0	COG3418@1|root,COG3418@2|Bacteria,1VF67@1239|Firmicutes,24SF3@186801|Clostridia,36NW1@31979|Clostridiaceae	186801|Clostridia	NOU	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
WZS3_k127_5641495_0	1408422.JHYF01000011_gene3493	1.068e-120	406.0	COG1256@1|root,COG1256@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia,36DE8@31979|Clostridiaceae	186801|Clostridia	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WZS3_k127_5641495_1	1304284.L21TH_2572	2.142e-30	122.0	COG1344@1|root,COG1344@2|Bacteria,1TPDT@1239|Firmicutes,248FN@186801|Clostridia,36FHE@31979|Clostridiaceae	186801|Clostridia	N	Belongs to the bacterial flagellin family	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WZS3_k127_5648399_1	641112.ACOK01000099_gene320	1.475e-88	298.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
WZS3_k127_5648399_0	1384066.JAGT01000001_gene892	5.403e-295	919.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WGZR@541000|Ruminococcaceae	186801|Clostridia	G	Hydrolase Family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WZS3_k127_5648399_2	265729.GS18_0207260	5.939e-42	164.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,1ZB1T@1386|Bacillus	91061|Bacilli	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
WZS3_k127_5658876_0	138119.DSY1742	3.661e-97	327.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,247S9@186801|Clostridia,260HQ@186807|Peptococcaceae	186801|Clostridia	H	biotin lipoate A B protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
WZS3_k127_5658876_3	903814.ELI_2272	2.367e-12	70.0	COG2732@1|root,COG2732@2|Bacteria,1U5YG@1239|Firmicutes,25PYJ@186801|Clostridia,25XX9@186806|Eubacteriaceae	186801|Clostridia	K	Barstar (barnase inhibitor)	-	-	-	ko:K03623	-	-	-	-	ko00000	-	-	-	Barstar
WZS3_k127_5658876_1	994573.T472_0209530	7.681e-51	185.0	COG4290@1|root,COG4290@2|Bacteria,1V7IV@1239|Firmicutes,24JGG@186801|Clostridia,36E4I@31979|Clostridiaceae	186801|Clostridia	F	PFAM Guanine-specific ribonuclease N1	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
WZS3_k127_5658876_2	411467.BACCAP_00623	6.908e-14	72.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,2695U@186813|unclassified Clostridiales	186801|Clostridia	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
WZS3_k127_5672487_1	1033737.CAEV01000111_gene3396	1.113e-60	214.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,36FD9@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K19081	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
WZS3_k127_5672487_0	1089548.KI783301_gene1078	9.133e-127	409.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli,3WE9R@539002|Bacillales incertae sedis	91061|Bacilli	V	ABC transporter	XK27_05695	-	-	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	M00258,M00731,M00737	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.134	-	-	ABC_tran
WZS3_k127_5672487_2	318464.IO99_05030	0.0002798	43.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,36EQ4@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
WZS3_k127_5678092_0	1540257.JQMW01000009_gene2853	9.546e-199	628.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,36EMB@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_5678092_1	536227.CcarbDRAFT_0878	5.807e-155	498.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E4P@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_5681353_0	1304284.L21TH_1664	1.601e-107	370.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EVU@31979|Clostridiaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,sCache_2
WZS3_k127_5689153_4	1408422.JHYF01000002_gene2351	5.722e-33	132.0	COG2208@1|root,COG2208@2|Bacteria,1TQY5@1239|Firmicutes,249WB@186801|Clostridia,36EX3@31979|Clostridiaceae	186801|Clostridia	KT	Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,MASE3,PAS_4,PAS_9,SpoIIE
WZS3_k127_5689153_2	1408422.JHYF01000015_gene391	9.207e-46	171.0	COG4189@1|root,COG4189@2|Bacteria,1UHX2@1239|Firmicutes,25E60@186801|Clostridia,36P7F@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
WZS3_k127_5689153_1	293826.Amet_2915	1.409e-71	262.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,36EUU@31979|Clostridiaceae	186801|Clostridia	E	family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
WZS3_k127_5689153_3	1304284.L21TH_2050	2.172e-38	157.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,248M5@186801|Clostridia,36FFZ@31979|Clostridiaceae	186801|Clostridia	C	iron-sulfur cluster-binding protein	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
WZS3_k127_5689153_0	1304284.L21TH_2051	1.717e-179	567.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,36DZ7@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS3_k127_5697608_0	1511.CLOST_0858	1.436e-21	100.0	29URH@1|root,30G3H@2|Bacteria,1UF4K@1239|Firmicutes,25K5C@186801|Clostridia,25UEK@186804|Peptostreptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4860)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4860
WZS3_k127_5697608_3	796940.HMPREF9628_01435	5.411e-09	63.0	2BAJ8@1|root,323ZZ@2|Bacteria,1UF1R@1239|Firmicutes,25K2F@186801|Clostridia,25U7Q@186804|Peptostreptococcaceae	186801|Clostridia	S	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WZS3_k127_5697608_2	1511.CLOST_0860	9.921e-14	79.0	2C7ZS@1|root,300B5@2|Bacteria,1UF8Z@1239|Firmicutes,25K9P@186801|Clostridia,25UBE@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5697608_1	796940.HMPREF9628_01437	3.926e-15	77.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,25SRY@186804|Peptostreptococcaceae	186801|Clostridia	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS3_k127_5720833_0	1511.CLOST_2429	0.0	1307.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,25QUT@186804|Peptostreptococcaceae	186801|Clostridia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
WZS3_k127_5720833_1	946077.W5A_01065	1.058e-42	159.0	COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,1I33I@117743|Flavobacteriia	976|Bacteroidetes	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WZS3_k127_5720833_2	1280390.CBQR020000097_gene2192	3.607e-21	95.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HGB5@91061|Bacilli,26RSX@186822|Paenibacillaceae	91061|Bacilli	T	Heme response regulator HssR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_5730178_0	221027.JO40_04365	2.436e-124	402.0	COG3842@1|root,COG3842@2|Bacteria,2J5T3@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
WZS3_k127_5730178_1	1304284.L21TH_1157	1.303e-87	294.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,36GJ7@31979|Clostridiaceae	186801|Clostridia	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_5732334_2	639282.DEFDS_1487	1.011e-24	104.0	COG0358@1|root,COG0358@2|Bacteria,2GEUD@200930|Deferribacteres	200930|Deferribacteres	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Toprim_4,Toprim_N,zf-CHC2
WZS3_k127_5732334_0	1121289.JHVL01000002_gene2328	3.96e-121	398.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,36E9Q@31979|Clostridiaceae	186801|Clostridia	F	Deoxyguanosinetriphosphate triphosphohydrolase	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
WZS3_k127_5732334_1	1453505.JASY01000010_gene3956	2.258e-38	145.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,1HY80@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WZS3_k127_5741471_4	748727.CLJU_c12610	2.718e-26	112.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,36F03@31979|Clostridiaceae	186801|Clostridia	T	Phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
WZS3_k127_5741471_0	1128398.Curi_c16810	2.314e-123	409.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,26869@186813|unclassified Clostridiales	186801|Clostridia	JK	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
WZS3_k127_5741471_2	1280685.AUKC01000025_gene1054	1.057e-65	231.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,4BXQG@830|Butyrivibrio	186801|Clostridia	S	Putative neutral zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
WZS3_k127_5741471_1	269799.Gmet_3339	3.183e-99	332.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WZS3_k127_5741471_3	941824.TCEL_01800	9.877e-51	184.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,36IPZ@31979|Clostridiaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WZS3_k127_5746800_3	1499498.EV05_0612	1.22e-11	66.0	COG1211@1|root,COG1211@2|Bacteria,1G08E@1117|Cyanobacteria,1MKPE@1212|Prochloraceae	1117|Cyanobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
WZS3_k127_5746800_1	338963.Pcar_0102	5.069e-64	223.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,43UN0@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
WZS3_k127_5746800_2	869213.JCM21142_42031	1.419e-36	139.0	COG2158@1|root,COG2158@2|Bacteria	2|Bacteria	S	Cysteine-rich small domain	cbiA	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
WZS3_k127_5746800_0	1111134.HMPREF1253_0421	1.251e-165	530.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,22FXI@1570339|Peptoniphilaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
WZS3_k127_576329_1	1121324.CLIT_14c00200	5.926e-68	241.0	COG4191@1|root,COG4191@2|Bacteria,1UJ9X@1239|Firmicutes,24GCW@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
WZS3_k127_576329_2	1128398.Curi_c26560	1.936e-65	232.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,26A4G@186813|unclassified Clostridiales	186801|Clostridia	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WZS3_k127_576329_0	340099.Teth39_0875	2.034e-140	458.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,42EXU@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WZS3_k127_576329_3	688269.Theth_0773	3.525e-15	77.0	COG0182@1|root,COG0182@2|Bacteria,2GCAP@200918|Thermotogae	200918|Thermotogae	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
WZS3_k127_5784709_5	994573.T472_0211420	2.734e-11	65.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia,36F05@31979|Clostridiaceae	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WZS3_k127_5784709_4	1237149.C900_03170	4.474e-31	128.0	COG1670@1|root,COG1670@2|Bacteria,4NSIH@976|Bacteroidetes	976|Bacteroidetes	J	acetyltransferase	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WZS3_k127_5784709_1	350688.Clos_1008	5.725e-116	385.0	28HHD@1|root,2Z7T3@2|Bacteria,1TRKJ@1239|Firmicutes,24A0Y@186801|Clostridia,36GI9@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF3810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
WZS3_k127_5784709_2	158189.SpiBuddy_0449	1.44e-52	193.0	29HWC@1|root,304TF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
WZS3_k127_5784709_3	666686.B1NLA3E_11880	2.862e-31	128.0	COG0716@1|root,COG0716@2|Bacteria,1VFBM@1239|Firmicutes,4HYKX@91061|Bacilli	91061|Bacilli	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5784709_6	1540257.JQMW01000011_gene2546	4.103e-11	71.0	COG1309@1|root,COG1309@2|Bacteria,1V7BK@1239|Firmicutes,24HI0@186801|Clostridia,36I31@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	grdR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_5784709_0	888055.HMPREF9015_00246	1.669e-245	773.0	COG1048@1|root,COG1048@2|Bacteria,378WX@32066|Fusobacteria	32066|Fusobacteria	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WZS3_k127_5804329_2	1347392.CCEZ01000012_gene2539	4.511e-32	129.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,36WU0@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WZS3_k127_5804329_1	1121324.CLIT_13c01050	3.63e-205	647.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,25R2A@186804|Peptostreptococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WZS3_k127_5804329_0	1304284.L21TH_0588	1.952e-262	820.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,36DW7@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
WZS3_k127_5804329_3	1230342.CTM_17751	1.661e-12	75.0	COG1390@1|root,COG1390@2|Bacteria,1VFFG@1239|Firmicutes,24PH0@186801|Clostridia,36MAV@31979|Clostridiaceae	186801|Clostridia	C	COG1390 Archaeal vacuolar-type H -ATPase subunit E	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
WZS3_k127_5813623_2	198094.BA_2707	4.132e-09	68.0	COG0454@1|root,COG0456@2|Bacteria,1TQ7M@1239|Firmicutes,4HGSS@91061|Bacilli,1ZGQ3@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_5813623_0	1385511.N783_01170	1.247e-81	284.0	COG0400@1|root,COG0400@2|Bacteria,1V5GR@1239|Firmicutes,4HJG0@91061|Bacilli	91061|Bacilli	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
WZS3_k127_5813623_1	332101.JIBU02000013_gene1373	7.318e-52	185.0	COG2872@1|root,COG2872@2|Bacteria,1V2RR@1239|Firmicutes,25CM7@186801|Clostridia	186801|Clostridia	S	Threonyl and Alanyl tRNA synthetase second additional domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_SAD
WZS3_k127_5839209_1	1274374.CBLK010000059_gene344	3.07e-185	596.0	COG0826@1|root,COG0826@2|Bacteria,1TS0G@1239|Firmicutes,4HE7K@91061|Bacilli,26R6W@186822|Paenibacillaceae	91061|Bacilli	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
WZS3_k127_5839209_0	350688.Clos_2162	7.761e-220	702.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,36DXT@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_5850494_2	1321786.HMPREF1992_01832	4.623e-46	176.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H2C6@909932|Negativicutes	909932|Negativicutes	S	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
WZS3_k127_5850494_4	1123009.AUID01000001_gene1005	9.075e-11	69.0	2DR7G@1|root,33AJA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5850494_1	1304284.L21TH_0600	5.512e-84	297.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,36FHQ@31979|Clostridiaceae	186801|Clostridia	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
WZS3_k127_5850494_3	1158318.ATXC01000001_gene886	1.244e-20	93.0	COG0855@1|root,COG0855@2|Bacteria	2|Bacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	iJN746.PP_5217	PP_kinase,PP_kinase_C,PP_kinase_N
WZS3_k127_5850494_0	1304284.L21TH_0599	1.486e-128	422.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,36EP5@31979|Clostridiaceae	186801|Clostridia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WZS3_k127_5873290_0	1121289.JHVL01000017_gene728	5.435e-181	582.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,36EHU@31979|Clostridiaceae	186801|Clostridia	E	Family 5	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WZS3_k127_5873290_1	760011.Spico_0769	5.785e-50	183.0	COG3345@1|root,COG3345@2|Bacteria,2J68S@203691|Spirochaetes	203691|Spirochaetes	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
WZS3_k127_5885903_2	941824.TCEL_00787	3.272e-51	191.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,24AF9@186801|Clostridia,36JPW@31979|Clostridiaceae	186801|Clostridia	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
WZS3_k127_5885903_1	941824.TCEL_00786	1.947e-53	202.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,36MFI@31979|Clostridiaceae	186801|Clostridia	O	prohibitin homologues	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
WZS3_k127_5885903_0	293826.Amet_2164	1.46e-94	316.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,36FA1@31979|Clostridiaceae	186801|Clostridia	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroF	-	2.5.1.54,5.4.99.5	ko:K01626,ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
WZS3_k127_5885903_3	1541959.KQ51_01229	2.104e-44	166.0	COG4843@1|root,COG4843@2|Bacteria,3WV0G@544448|Tenericutes	544448|Tenericutes	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
WZS3_k127_5891694_0	1511.CLOST_0330	2.337e-88	294.0	COG1247@1|root,COG1247@2|Bacteria,1VRJ4@1239|Firmicutes,24AE5@186801|Clostridia	186801|Clostridia	M	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5891694_1	1121289.JHVL01000056_gene2959	1.029e-63	229.0	COG0644@1|root,COG0644@2|Bacteria,1UZT1@1239|Firmicutes,25DJ8@186801|Clostridia,36HJZ@31979|Clostridiaceae	186801|Clostridia	C	oxidoreductase	cbrA	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8
WZS3_k127_589579_2	457570.Nther_0164	2.48e-10	61.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia	186801|Clostridia	K	PFAM Transcription factor CarD	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
WZS3_k127_589579_0	350688.Clos_0461	2.921e-113	377.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,248F4@186801|Clostridia,36DKW@31979|Clostridiaceae	186801|Clostridia	S	PFAM PilT protein domain protein	yacL	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_4,TRAM
WZS3_k127_589579_1	1121289.JHVL01000023_gene71	9.42e-34	136.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,36EIP@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
WZS3_k127_591856_3	1460634.JCM19037_325	8.062e-06	55.0	2BWFS@1|root,30CNM@2|Bacteria,1V48G@1239|Firmicutes,4HUU0@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_591856_1	350688.Clos_0638	1.902e-133	433.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha
WZS3_k127_591856_2	1123009.AUID01000009_gene441	6.504e-117	381.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,26AP9@186813|unclassified Clostridiales	186801|Clostridia	C	Electron transfer flavoprotein domain	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
WZS3_k127_591856_0	350688.Clos_0636	1.102e-178	568.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,36DR1@31979|Clostridiaceae	186801|Clostridia	I	acyl-CoA dehydrogenase	bcd2	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
WZS3_k127_5921598_2	536232.CLM_1937	1.218e-47	175.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,36EB0@31979|Clostridiaceae	186801|Clostridia	S	S1, RNA binding domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
WZS3_k127_5921598_3	935948.KE386494_gene576	1.278e-09	66.0	COG3027@1|root,COG3027@2|Bacteria,1VIXT@1239|Firmicutes,24RYN@186801|Clostridia,42HJ3@68295|Thermoanaerobacterales	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
WZS3_k127_5921598_0	350688.Clos_1836	3.293e-253	803.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,36EFY@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WZS3_k127_5921598_1	1304880.JAGB01000002_gene1917	1.269e-48	184.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
WZS3_k127_5923907_0	1121324.CLIT_23c01120	2.343e-150	489.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25QKI@186804|Peptostreptococcaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
WZS3_k127_5923907_1	1128398.Curi_c10850	1.619e-62	218.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,2698D@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WZS3_k127_5923907_2	1121324.CLIT_17c00150	5.098e-44	164.0	COG1406@1|root,COG1406@2|Bacteria,1VD18@1239|Firmicutes,24HMR@186801|Clostridia	186801|Clostridia	N	PFAM CheC domain protein	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
WZS3_k127_5999479_2	457396.CSBG_02548	3.961e-24	103.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,36F52@31979|Clostridiaceae	186801|Clostridia	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_5999479_1	1122962.AULH01000001_gene1537	9.62e-43	162.0	COG4702@1|root,COG4702@2|Bacteria,1RHRX@1224|Proteobacteria,2UDVC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the UPF0303 family	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
WZS3_k127_5999479_0	521045.Kole_1235	3.141e-71	255.0	COG2206@1|root,COG2206@2|Bacteria,2GCYD@200918|Thermotogae	200918|Thermotogae	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS3_k127_6000723_2	350688.Clos_1440	5.331e-37	143.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,36E63@31979|Clostridiaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	yloV	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
WZS3_k127_6000723_3	1408422.JHYF01000002_gene2613	2.957e-36	140.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,36JGK@31979|Clostridiaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WZS3_k127_6000723_5	1511.CLOST_1845	2.972e-23	99.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,25RTD@186804|Peptostreptococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WZS3_k127_6000723_4	180332.JTGN01000001_gene5004	1.301e-27	120.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
WZS3_k127_6000723_1	1301100.HG529233_gene7344	5.406e-91	304.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,36EV9@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WZS3_k127_6000723_0	1121324.CLIT_23c03080	2.732e-91	309.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,25QPZ@186804|Peptostreptococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
WZS3_k127_6000723_6	697281.Mahau_0989	3.38e-07	58.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,42EW8@68295|Thermoanaerobacterales	186801|Clostridia	KLT	Serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WZS3_k127_6012971_2	357809.Cphy_2488	3.914e-114	377.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,21XRN@1506553|Lachnoclostridium	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192,2.1.1.224	ko:K06941,ko:K15632	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Fer4_14,Radical_SAM
WZS3_k127_6012971_8	592026.GCWU0000282_001040	1.118e-21	98.0	2CXVJ@1|root,32T2R@2|Bacteria,1VB0Y@1239|Firmicutes,24MMS@186801|Clostridia	186801|Clostridia	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
WZS3_k127_6012971_7	398512.JQKC01000048_gene358	3.585e-34	149.0	COG2133@1|root,COG3291@1|root,COG3979@1|root,COG4733@1|root,COG5184@1|root,COG5297@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3979@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,COG5297@2|Bacteria,1TQ2T@1239|Firmicutes,24EP0@186801|Clostridia,3WI1H@541000|Ruminococcaceae	186801|Clostridia	MU	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Paired_CXXCH_1,fn3
WZS3_k127_6012971_5	926561.KB900623_gene893	5.974e-82	282.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3WB1Y@53433|Halanaerobiales	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WZS3_k127_6012971_1	1121324.CLIT_4c00930	1.172e-142	460.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,25R00@186804|Peptostreptococcaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
WZS3_k127_6012971_3	350688.Clos_2538	4.474e-104	344.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,36UH9@31979|Clostridiaceae	186801|Clostridia	P	spermidine putrescine transport system, permease	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
WZS3_k127_6012971_4	545697.HMPREF0216_02070	1.444e-94	317.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,36EF3@31979|Clostridiaceae	186801|Clostridia	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
WZS3_k127_6012971_0	1128398.Curi_c09520	8.625e-158	503.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,268E5@186813|unclassified Clostridiales	186801|Clostridia	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
WZS3_k127_6012971_6	1304284.L21TH_2034	3.539e-73	250.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,36F4A@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
WZS3_k127_605885_2	1280692.AUJL01000027_gene2135	4.595e-29	121.0	COG3048@1|root,COG3048@2|Bacteria,1TPAH@1239|Firmicutes,249NA@186801|Clostridia,36ED7@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the serine threonine dehydratase family. DsdA subfamily	dsdA	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	PALP
WZS3_k127_605885_0	1511.CLOST_2542	1.917e-31	136.0	COG2378@1|root,COG2378@2|Bacteria,1UY06@1239|Firmicutes,24BIC@186801|Clostridia	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
WZS3_k127_605885_1	545243.BAEV01000034_gene1716	5.073e-30	124.0	COG3708@1|root,COG3708@2|Bacteria,1UUU8@1239|Firmicutes,24IE8@186801|Clostridia,36JBT@31979|Clostridiaceae	186801|Clostridia	K	transcription activator, effector binding	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2
WZS3_k127_606765_2	1408439.JHXW01000002_gene792	1.272e-59	207.0	COG1129@1|root,COG1129@2|Bacteria,37997@32066|Fusobacteria	32066|Fusobacteria	G	Part of the ABC transporter complex MglABC involved in galactose methyl galactoside import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
WZS3_k127_606765_1	941824.TCEL_02098	3.16e-139	450.0	COG4211@1|root,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia,36UND@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	mglC	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
WZS3_k127_606765_3	857293.CAAU_0585	4.02e-13	69.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,36FQ1@31979|Clostridiaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
WZS3_k127_606765_0	1033810.HLPCO_000714	3.832e-219	694.0	COG1874@1|root,COG1874@2|Bacteria,2NP1U@2323|unclassified Bacteria	2|Bacteria	G	Beta-galactosidase trimerisation domain	bgaA	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
WZS3_k127_6099804_0	33035.JPJF01000053_gene1590	2.075e-126	412.0	COG3250@1|root,COG3250@2|Bacteria,1TSMY@1239|Firmicutes,24B54@186801|Clostridia	186801|Clostridia	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
WZS3_k127_6099804_1	1033737.CAEV01000056_gene3724	3.046e-50	180.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,24J9K@186801|Clostridia,36K63@31979|Clostridiaceae	186801|Clostridia	P	Alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
WZS3_k127_6099804_2	580327.Tthe_2595	3.876e-08	55.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,42EMH@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	garK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
WZS3_k127_6112650_1	1347392.CCEZ01000074_gene1904	9.123e-81	279.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,36DX8@31979|Clostridiaceae	186801|Clostridia	E	Dipeptidase	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS3_k127_6112650_0	1280689.AUJC01000001_gene2521	4.308e-118	386.0	COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,25E5A@186801|Clostridia,36EIH@31979|Clostridiaceae	186801|Clostridia	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WZS3_k127_6112650_2	1121864.OMO_00607	0.0006651	43.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,4HD6T@91061|Bacilli,4AZD5@81852|Enterococcaceae	91061|Bacilli	KL	HELICc2	uvrB3	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
WZS3_k127_6129979_0	1511.CLOST_0728	5.689e-72	259.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
WZS3_k127_6129979_1	318464.IO99_15495	1.588e-51	190.0	COG0778@1|root,COG0778@2|Bacteria,1UY72@1239|Firmicutes,248YJ@186801|Clostridia,36FEA@31979|Clostridiaceae	186801|Clostridia	C	nitroreductase	sagB	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WZS3_k127_6152085_2	1292035.H476_0470	2.145e-49	177.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,25QE3@186804|Peptostreptococcaceae	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WZS3_k127_6152085_3	293826.Amet_2343	1.687e-20	94.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,36MPE@31979|Clostridiaceae	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
WZS3_k127_6152085_4	411467.BACCAP_02057	1.76e-19	88.0	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,269UY@186813|unclassified Clostridiales	186801|Clostridia	S	Six-cysteine peptide SCIFF	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
WZS3_k127_6152085_0	350688.Clos_1718	4.496e-203	640.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,36DZR@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
WZS3_k127_6152085_1	1304284.L21TH_1266	1.32e-56	201.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,36IWM@31979|Clostridiaceae	186801|Clostridia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
WZS3_k127_6152822_6	1232443.BAIA02000071_gene553	3.098e-67	244.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia	186801|Clostridia	QT	Psort location Cytoplasmic, score	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
WZS3_k127_6152822_7	350688.Clos_0870	3.919e-33	140.0	2DBAX@1|root,2Z84Q@2|Bacteria,1VHQG@1239|Firmicutes,24KJ8@186801|Clostridia,36PVS@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
WZS3_k127_6152822_2	350688.Clos_0871	1.416e-181	581.0	COG0074@1|root,COG0074@2|Bacteria,1UJ4F@1239|Firmicutes,24AQG@186801|Clostridia,36E6R@31979|Clostridiaceae	186801|Clostridia	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,DUF1116,Ligase_CoA
WZS3_k127_6152822_11	1408422.JHYF01000016_gene93	3.374e-16	79.0	COG0074@1|root,COG0074@2|Bacteria,1VMF5@1239|Firmicutes,25F0R@186801|Clostridia	186801|Clostridia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6152822_0	350688.Clos_0873	1.489e-223	698.0	COG0074@1|root,COG0074@2|Bacteria,1UJ4F@1239|Firmicutes,24AQG@186801|Clostridia,36HIH@31979|Clostridiaceae	186801|Clostridia	C	Protein of unknown function (DUF1116)	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,DUF1116,Ligase_CoA
WZS3_k127_6152822_3	350688.Clos_0874	1.809e-161	509.0	COG1878@1|root,COG1878@2|Bacteria,1V07X@1239|Firmicutes,24EXW@186801|Clostridia,36GI4@31979|Clostridiaceae	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
WZS3_k127_6152822_1	350688.Clos_0876	2.906e-183	580.0	COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,36FMV@31979|Clostridiaceae	186801|Clostridia	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16,2.8.3.19	ko:K07749,ko:K18702	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
WZS3_k127_6152822_4	865861.AZSU01000002_gene2726	3.223e-72	252.0	COG1975@1|root,COG1975@2|Bacteria,1V514@1239|Firmicutes,25D6P@186801|Clostridia,36U7R@31979|Clostridiaceae	186801|Clostridia	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
WZS3_k127_6152822_5	545697.HMPREF0216_02286	4.413e-72	252.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,36E0K@31979|Clostridiaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
WZS3_k127_6152822_9	1449050.JNLE01000003_gene2466	6.308e-30	128.0	COG1192@1|root,COG1192@2|Bacteria,1UI78@1239|Firmicutes,25ECF@186801|Clostridia,36I2D@31979|Clostridiaceae	186801|Clostridia	D	Involved in chromosome partitioning	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6152822_10	767817.Desgi_3969	7.978e-30	127.0	COG2068@1|root,COG2068@2|Bacteria,1UMIC@1239|Firmicutes,24M9Z@186801|Clostridia	186801|Clostridia	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
WZS3_k127_6152822_8	926569.ANT_04230	6.124e-31	128.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi	200795|Chloroflexi	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WZS3_k127_615786_0	1226325.HMPREF1548_04618	1.346e-146	470.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,36VSN@31979|Clostridiaceae	186801|Clostridia	G	MFS/sugar transport protein	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
WZS3_k127_615786_1	931626.Awo_c32170	1.716e-136	448.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,25ZUT@186806|Eubacteriaceae	186801|Clostridia	H	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WZS3_k127_6181921_1	1313301.AUGC01000018_gene786	9.558e-55	195.0	COG0756@1|root,COG0756@2|Bacteria,4NNI4@976|Bacteroidetes	976|Bacteroidetes	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
WZS3_k127_6181921_0	1128398.Curi_c15480	8.536e-64	229.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,267UQ@186813|unclassified Clostridiales	186801|Clostridia	S	Peptidase M16 inactive domain	ymxG	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS3_k127_6197372_0	1121289.JHVL01000013_gene1618	2.988e-83	280.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,36DGA@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WZS3_k127_6197372_1	865861.AZSU01000001_gene227	4.709e-58	213.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,36DHP@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WZS3_k127_6201126_0	1511.CLOST_0712	1.527e-142	465.0	COG0312@1|root,COG0312@2|Bacteria,1TQJ5@1239|Firmicutes,24AGW@186801|Clostridia,25S3A@186804|Peptostreptococcaceae	186801|Clostridia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
WZS3_k127_6201126_1	273068.TTE2395	1.484e-89	311.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,42F58@68295|Thermoanaerobacterales	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
WZS3_k127_6201126_2	697281.Mahau_0618	1.389e-48	181.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,42EN9@68295|Thermoanaerobacterales	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WZS3_k127_6202330_6	1304880.JAGB01000001_gene790	1.857e-05	47.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia	186801|Clostridia	S	permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
WZS3_k127_6202330_3	350688.Clos_2450	2.1e-60	219.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,36DTH@31979|Clostridiaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
WZS3_k127_6202330_1	926692.AZYG01000085_gene758	7.427e-102	345.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,3WBA9@53433|Halanaerobiales	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
WZS3_k127_6202330_5	857293.CAAU_2477	1.733e-25	108.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,36KFP@31979|Clostridiaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WZS3_k127_6202330_0	1304284.L21TH_1820	3.826e-250	782.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,36E1F@31979|Clostridiaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WZS3_k127_6202330_4	1408422.JHYF01000006_gene1080	5.463e-35	141.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_6202330_2	1408422.JHYF01000006_gene1081	7.495e-67	236.0	COG0596@1|root,COG0596@2|Bacteria,1UMWY@1239|Firmicutes,24EAB@186801|Clostridia,36DCV@31979|Clostridiaceae	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
WZS3_k127_6204066_1	309799.DICTH_0379	1.954e-85	300.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Cu_amine_oxidN1,DLH,DUF3887,Hydrolase_4,Peptidase_S9
WZS3_k127_6204066_0	1120998.AUFC01000043_gene1129	3.434e-95	325.0	COG0426@1|root,COG1251@1|root,COG0426@2|Bacteria,COG1251@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WDA4@538999|Clostridiales incertae sedis	186801|Clostridia	C	Flavodoxin	fprA2	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B,Pyr_redox_2
WZS3_k127_6204066_4	350688.Clos_2168	7.475e-27	109.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,36MM3@31979|Clostridiaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rd	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592	-	-	-	-	-	-	-	-	-	-	Rubredoxin
WZS3_k127_6204066_2	1304284.L21TH_0877	8.821e-42	157.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24NZG@186801|Clostridia,36VU4@31979|Clostridiaceae	186801|Clostridia	P	Ferric uptake regulator family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WZS3_k127_6204066_3	573413.Spirs_0603	5.092e-27	111.0	COG2033@1|root,COG2033@2|Bacteria,2J8F0@203691|Spirochaetes	203691|Spirochaetes	C	Desulfoferrodoxin ferrous iron-binding domain	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
WZS3_k127_6206623_1	1499689.CCNN01000014_gene3278	1.193e-54	199.0	COG0454@1|root,COG0456@2|Bacteria,1VAP5@1239|Firmicutes,25DBS@186801|Clostridia,36U9D@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
WZS3_k127_6206623_0	1511.CLOST_1222	5.095e-253	786.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25QPU@186804|Peptostreptococcaceae	186801|Clostridia	E	Aminotransferase	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS10450	Aminotran_1_2
WZS3_k127_6206623_2	588581.Cpap_2838	1.152e-42	157.0	2CET8@1|root,2Z7N2@2|Bacteria,1TT9T@1239|Firmicutes,24AN8@186801|Clostridia,3WIG0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6214411_3	1033734.CAET01000048_gene1722	2.69e-58	207.0	COG4990@1|root,COG4990@2|Bacteria,1V6DF@1239|Firmicutes,4IQE7@91061|Bacilli,1ZRIY@1386|Bacillus	91061|Bacilli	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
WZS3_k127_6214411_1	981383.AEWH01000052_gene794	1.306e-76	263.0	COG1794@1|root,COG1794@2|Bacteria,1TQ6M@1239|Firmicutes,4HEYS@91061|Bacilli	91061|Bacilli	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
WZS3_k127_6214411_0	1408422.JHYF01000013_gene495	9.509e-120	393.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,36E13@31979|Clostridiaceae	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS3_k127_6214411_2	574376.BAMA_18720	4.976e-69	240.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,1ZBGZ@1386|Bacillus	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WZS3_k127_6214487_3	1033810.HLPCO_002325	1.777e-51	190.0	COG2308@1|root,COG2308@2|Bacteria,2NR97@2323|unclassified Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2,GSP_synth
WZS3_k127_6214487_5	555088.DealDRAFT_1272	5.041e-33	133.0	COG0346@1|root,COG0346@2|Bacteria,1VD8Q@1239|Firmicutes,24JY7@186801|Clostridia	186801|Clostridia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
WZS3_k127_6214487_1	1403313.AXBR01000010_gene1057	7.115e-163	522.0	COG0477@1|root,COG0477@2|Bacteria,1UHRM@1239|Firmicutes,4ISTP@91061|Bacilli,1ZSG1@1386|Bacillus	91061|Bacilli	EGP	Transmembrane secretion effector	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1
WZS3_k127_6214487_2	1293054.HSACCH_01952	6.778e-95	318.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia,3WAP8@53433|Halanaerobiales	186801|Clostridia	O	TIGRFAM FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WZS3_k127_6214487_0	1408422.JHYF01000008_gene3589	1.902e-244	760.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,36G21@31979|Clostridiaceae	186801|Clostridia	O	FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WZS3_k127_6214487_4	656519.Halsa_2063	1.867e-35	146.0	COG0719@1|root,COG0719@2|Bacteria,1TRQJ@1239|Firmicutes,24ANC@186801|Clostridia	186801|Clostridia	O	SufB sufD domain protein	sufD	-	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
WZS3_k127_6224122_1	1034769.KB910518_gene3847	1.084e-42	166.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	pqrA	-	-	ko:K05804,ko:K13652,ko:K13653	-	M00647,M00767	-	-	ko00000,ko00002,ko03000,ko03036	-	-	-	BLUF,GyrI-like,HTH_18,HTH_AraC
WZS3_k127_6224122_2	1449050.JNLE01000005_gene4291	1.285e-36	143.0	COG0454@1|root,COG0454@2|Bacteria,1W6JE@1239|Firmicutes,25FE3@186801|Clostridia,36M42@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
WZS3_k127_6224122_0	269797.Mbar_A1202	1.297e-125	408.0	COG1680@1|root,arCOG00771@2157|Archaea	2157|Archaea	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A1202	Beta-lactamase
WZS3_k127_6238875_0	768706.Desor_2832	1.848e-69	255.0	COG2199@1|root,COG2206@1|root,COG3275@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,COG3275@2|Bacteria,1V6WM@1239|Firmicutes,25E5R@186801|Clostridia,2603J@186807|Peptococcaceae	186801|Clostridia	T	diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GGDEF,HD,HD_5,HisKA_7TM,PAS_9
WZS3_k127_6238875_1	858215.Thexy_0244	5.795e-69	245.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24A9J@186801|Clostridia	186801|Clostridia	H	PFAM UbiA prenyltransferase	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
WZS3_k127_6238875_2	318464.IO99_10925	1.129e-08	57.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia,36DT5@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WZS3_k127_6241236_1	411902.CLOBOL_01642	1.252e-47	179.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,21XTZ@1506553|Lachnoclostridium	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase,dCache_1
WZS3_k127_6241236_0	457405.FSDG_02092	2.678e-75	260.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,379GJ@32066|Fusobacteria	32066|Fusobacteria	KT	response regulator	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
WZS3_k127_6244385_2	1321778.HMPREF1982_04396	1.192e-64	224.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,267J7@186813|unclassified Clostridiales	186801|Clostridia	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS3_k127_6244385_0	1410668.JNKC01000004_gene56	2.526e-142	458.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,36DQT@31979|Clostridiaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
WZS3_k127_6244385_1	1321778.HMPREF1982_04398	1.746e-133	430.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes	1239|Firmicutes	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS3_k127_6244385_3	1121335.Clst_1255	2.734e-11	65.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS14365	CM_2,SKI,Shikimate_DH,Shikimate_dh_N
WZS3_k127_6267646_3	1216007.AOPM01000022_gene3164	3.404e-39	149.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,1T03S@1236|Gammaproteobacteria,2Q4MD@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
WZS3_k127_6267646_0	1128398.Curi_c20470	1.1e-109	362.0	COG3173@1|root,COG3173@2|Bacteria,1TUSQ@1239|Firmicutes,25MTM@186801|Clostridia,26C57@186813|unclassified Clostridiales	186801|Clostridia	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6267646_5	768706.Desor_3557	6.892e-21	99.0	2DN8M@1|root,32W40@2|Bacteria,1UPVD@1239|Firmicutes,24NS7@186801|Clostridia,26638@186807|Peptococcaceae	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
WZS3_k127_6267646_2	293826.Amet_2244	1.597e-46	171.0	COG0454@1|root,COG0456@2|Bacteria,1VAQ8@1239|Firmicutes,24KVY@186801|Clostridia,36KAE@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
WZS3_k127_6267646_4	1385513.N780_15730	1.302e-38	151.0	COG1670@1|root,COG1670@2|Bacteria,1V2EM@1239|Firmicutes	1239|Firmicutes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_6267646_1	350688.Clos_2294	6.78e-53	199.0	COG0639@1|root,COG0639@2|Bacteria,1UFKZ@1239|Firmicutes,24HCD@186801|Clostridia,36J8R@31979|Clostridiaceae	186801|Clostridia	T	Protein phosphatase 2A homologues, catalytic domain.	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WZS3_k127_6276262_0	696369.KI912183_gene2577	4.271e-148	477.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,260RR@186807|Peptococcaceae	186801|Clostridia	I	BadF BadG BcrA BcrD	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
WZS3_k127_6276262_2	445335.CBN_0535	5.815e-19	97.0	COG2199@1|root,COG3706@2|Bacteria,1V9S3@1239|Firmicutes,24B6H@186801|Clostridia,36HPD@31979|Clostridiaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WZS3_k127_6276262_1	1304284.L21TH_0556	1.927e-85	287.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,36DTB@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WZS3_k127_6281470_2	1239962.C943_02087	6.863e-51	184.0	COG3832@1|root,COG3865@1|root,COG3832@2|Bacteria,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,47PVI@768503|Cytophagia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
WZS3_k127_6281470_1	1189612.A33Q_1780	1.253e-57	203.0	COG3607@1|root,COG3607@2|Bacteria,4NRTG@976|Bacteroidetes,47XTH@768503|Cytophagia	976|Bacteroidetes	S	Glyoxalase-like domain	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
WZS3_k127_6281470_3	1125700.HMPREF9195_00418	6.166e-44	163.0	COG3597@1|root,COG3597@2|Bacteria,2JBBN@203691|Spirochaetes	203691|Spirochaetes	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6281470_0	1123288.SOV_3c08100	6.089e-77	267.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,4H30J@909932|Negativicutes	909932|Negativicutes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,Hpt,PAS_8,Response_reg
WZS3_k127_6287997_1	1128398.Curi_c20790	2.675e-98	341.0	2DBE5@1|root,2Z8QQ@2|Bacteria,1TPFD@1239|Firmicutes,24E93@186801|Clostridia,269SK@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6287997_2	865861.AZSU01000001_gene168	1.381e-46	170.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,36IPB@31979|Clostridiaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
WZS3_k127_6287997_0	572480.Arnit_0947	1.814e-145	469.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2YMB7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WZS3_k127_6288800_0	742740.HMPREF9474_01920	1.198e-165	530.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,21YDI@1506553|Lachnoclostridium	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_6288800_2	1304284.L21TH_1982	1.799e-47	181.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25930@186801|Clostridia,36DVP@31979|Clostridiaceae	186801|Clostridia	EH	Aminotransferase class IV	ilvE2	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
WZS3_k127_6288800_1	1121324.CLIT_13c00470	2.117e-96	331.0	COG4591@1|root,COG4591@2|Bacteria,1VBN5@1239|Firmicutes,25EBV@186801|Clostridia	186801|Clostridia	M	permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS3_k127_6301994_0	935948.KE386494_gene413	1.052e-112	370.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,42F3H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	msmX	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE,TOBE_2
WZS3_k127_6301994_1	293826.Amet_3324	4.871e-09	67.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,36UIJ@31979|Clostridiaceae	186801|Clostridia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
WZS3_k127_6331031_0	1304284.L21TH_1605	7.086e-150	482.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,36DWA@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
WZS3_k127_6331031_1	941824.TCEL_00110	3.363e-103	344.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,36ESA@31979|Clostridiaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WZS3_k127_6331031_2	293826.Amet_1678	5.137e-26	108.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,36E5W@31979|Clostridiaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
WZS3_k127_6342668_5	1131730.BAVI_24943	1.755e-47	174.0	COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HQZW@91061|Bacilli,1ZJND@1386|Bacillus	91061|Bacilli	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WZS3_k127_6342668_1	935837.JAEK01000027_gene1618	1.215e-121	398.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,4HAHH@91061|Bacilli,1ZF3T@1386|Bacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
WZS3_k127_6342668_0	1487921.DP68_01665	8.076e-173	550.0	COG0642@1|root,COG2205@2|Bacteria,1VS9T@1239|Firmicutes,24YTS@186801|Clostridia,36V6B@31979|Clostridiaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_6342668_4	935845.JADQ01000004_gene2074	2.724e-68	240.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,4HB3T@91061|Bacilli,26TWW@186822|Paenibacillaceae	91061|Bacilli	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_6342668_2	1128398.Curi_c11970	2.617e-102	344.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,2687M@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA2	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WZS3_k127_6342668_3	1280692.AUJL01000022_gene529	9.833e-77	268.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,36EZJ@31979|Clostridiaceae	186801|Clostridia	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_6342668_6	350688.Clos_2039	5.103e-40	154.0	COG0558@1|root,COG0558@2|Bacteria,1V35A@1239|Firmicutes,24IIY@186801|Clostridia,36J5D@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA2	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WZS3_k127_6342668_7	572480.Arnit_2840	5.947e-14	74.0	COG0834@1|root,COG0834@2|Bacteria,1RBDN@1224|Proteobacteria,43AG9@68525|delta/epsilon subdivisions,2YNH4@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	ET	glutamine-binding periplasmic protein	glnH	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WZS3_k127_6364036_0	1211814.CAPG01000064_gene3057	5.832e-186	599.0	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,4HAVB@91061|Bacilli,1ZBSM@1386|Bacillus	91061|Bacilli	G	Glycoside hydrolase, family 65	treP	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
WZS3_k127_6364036_1	1347087.CBYO010000005_gene677	2.537e-61	218.0	COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,4HGBH@91061|Bacilli	91061|Bacilli	S	Haloacid dehalogenase-like hydrolase	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
WZS3_k127_6364036_3	349521.HCH_00674	1.32e-52	206.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RSDZ@1236|Gammaproteobacteria,1XJM9@135619|Oceanospirillales	135619|Oceanospirillales	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_9
WZS3_k127_6364036_2	477974.Daud_0677	5.951e-56	207.0	COG3437@1|root,COG3437@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,264DA@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
WZS3_k127_6377691_4	1121324.CLIT_2c00960	5.294e-70	249.0	COG2119@1|root,COG2119@2|Bacteria,1UFX2@1239|Firmicutes,24DHF@186801|Clostridia,25RQZ@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
WZS3_k127_6377691_2	1304284.L21TH_0027	6.615e-82	275.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,36G5Z@31979|Clostridiaceae	186801|Clostridia	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,Rubrerythrin
WZS3_k127_6377691_1	1121324.CLIT_18c00250	6.741e-134	430.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia,25QMV@186804|Peptostreptococcaceae	186801|Clostridia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WZS3_k127_6377691_0	1304284.L21TH_0029	1.077e-172	547.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,36EW0@31979|Clostridiaceae	186801|Clostridia	C	pyruvate flavodoxin ferredoxin oxidoreductase domain protein	vorB	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WZS3_k127_6377691_5	1121289.JHVL01000017_gene740	2.382e-31	123.0	COG1143@1|root,COG1143@2|Bacteria,1UHZA@1239|Firmicutes,24QVY@186801|Clostridia,36UN5@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
WZS3_k127_6377691_3	1408422.JHYF01000003_gene658	8.475e-80	272.0	COG0455@1|root,COG0455@2|Bacteria,1V1FH@1239|Firmicutes,24DP7@186801|Clostridia,36UV9@31979|Clostridiaceae	186801|Clostridia	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	CbiA
WZS3_k127_6384448_1	720554.Clocl_2732	1.733e-45	169.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3WJ45@541000|Ruminococcaceae	186801|Clostridia	K	TIGRFAM transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WZS3_k127_6384448_0	1304880.JAGB01000003_gene1237	1.644e-150	487.0	COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,25E6C@186801|Clostridia	186801|Clostridia	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt1	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
WZS3_k127_640023_6	935948.KE386493_gene2361	7.722e-26	113.0	COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,24MM3@186801|Clostridia,42GDD@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM DivIVA family protein	divIVA	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
WZS3_k127_640023_4	1235279.C772_00605	1.409e-43	169.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli,26E3T@186818|Planococcaceae	91061|Bacilli	S	S4 RNA-binding domain	ylmH	-	-	-	-	-	-	-	-	-	-	-	S4
WZS3_k127_640023_8	639282.DEFDS_0998	3.769e-09	61.0	COG0762@1|root,COG0762@2|Bacteria,2GFIV@200930|Deferribacteres	200930|Deferribacteres	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
WZS3_k127_640023_5	293826.Amet_2803	4.646e-33	133.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,36I3V@31979|Clostridiaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
WZS3_k127_640023_3	509191.AEDB02000109_gene5091	1.227e-64	228.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3WGKD@541000|Ruminococcaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
WZS3_k127_640023_7	865861.AZSU01000003_gene1603	2.057e-24	117.0	COG0845@1|root,COG0845@2|Bacteria,1TRN9@1239|Firmicutes,248G2@186801|Clostridia,36INS@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_640023_2	293826.Amet_2855	2.329e-111	369.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,36EG4@31979|Clostridiaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WZS3_k127_640023_0	1408422.JHYF01000002_gene2547	7.988e-192	608.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,36DFQ@31979|Clostridiaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WZS3_k127_640023_1	445973.CLOBAR_02789	2.718e-144	469.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,25SXA@186804|Peptostreptococcaceae	186801|Clostridia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
WZS3_k127_640023_9	1506994.JNLQ01000002_gene2660	0.0002677	44.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,4BWN6@830|Butyrivibrio	186801|Clostridia	S	Multi-copper polyphenol oxidoreductase laccase	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
WZS3_k127_6417485_0	273068.TTE0745	1.305e-40	158.0	COG1655@1|root,COG1655@2|Bacteria,1UY0V@1239|Firmicutes,247VR@186801|Clostridia,42FER@68295|Thermoanaerobacterales	186801|Clostridia	K	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225,cNMP_binding
WZS3_k127_6417485_1	203119.Cthe_3153	9.888e-39	152.0	COG0406@1|root,COG0406@2|Bacteria,1VEMM@1239|Firmicutes,24GJW@186801|Clostridia	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
WZS3_k127_6417485_2	521460.Athe_2134	2.484e-09	59.0	COG1406@1|root,COG1406@2|Bacteria,1V6JI@1239|Firmicutes,25DXQ@186801|Clostridia,42H88@68295|Thermoanaerobacterales	186801|Clostridia	N	PFAM CheC domain protein	-	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
WZS3_k127_6444167_1	1304880.JAGB01000001_gene577	4.136e-68	237.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
WZS3_k127_6444167_2	445335.CBN_3283	3.637e-49	185.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,36E7E@31979|Clostridiaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	iHN637.CLJU_RS17580	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
WZS3_k127_6444167_0	720554.Clocl_2389	2.673e-121	396.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3WGC5@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
WZS3_k127_646103_4	588581.Cpap_3534	1.752e-32	131.0	COG0823@1|root,COG0823@2|Bacteria,1UI4E@1239|Firmicutes,250JT@186801|Clostridia,3WPAN@541000|Ruminococcaceae	186801|Clostridia	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
WZS3_k127_646103_1	903814.ELI_3000	1.657e-112	370.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,25VPW@186806|Eubacteriaceae	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS3_k127_646103_0	1511.CLOST_0768	2.677e-190	597.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,24958@186801|Clostridia	186801|Clostridia	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WZS3_k127_646103_3	1487921.DP68_05770	5.118e-63	218.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,36IRG@31979|Clostridiaceae	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WZS3_k127_646103_5	720554.Clocl_2974	1.147e-29	121.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,25B8J@186801|Clostridia,3WS4I@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS3_k127_646103_2	768710.DesyoDRAFT_1542	1.328e-103	340.0	COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,249JN@186801|Clostridia,260XR@186807|Peptococcaceae	186801|Clostridia	D	TIGRFAM arsenite-activated ATPase (arsA)	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
WZS3_k127_6476931_0	1117379.BABA_16567	1.81e-144	478.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1ZCBY@1386|Bacillus	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WZS3_k127_6480885_2	941824.TCEL_00515	3.797e-47	175.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,36DSY@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
WZS3_k127_6480885_1	536233.CLO_1488	1.314e-120	401.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
WZS3_k127_6480885_0	1121324.CLIT_23c04850	1.346e-228	716.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,25QU3@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WZS3_k127_6484695_2	697329.Rumal_3204	3.295e-70	243.0	COG0237@1|root,COG0237@2|Bacteria,1VTAH@1239|Firmicutes,25KRU@186801|Clostridia,3WQ98@541000|Ruminococcaceae	186801|Clostridia	H	dephospho-CoA kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6484695_1	44251.PDUR_09640	3.052e-72	248.0	COG0500@1|root,COG0500@2|Bacteria,1V4RN@1239|Firmicutes,4HT14@91061|Bacilli,26V4U@186822|Paenibacillaceae	91061|Bacilli	Q	SAM-dependent methyltransferase	ubiE6	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
WZS3_k127_6484695_4	138119.DSY4106	7.799e-34	134.0	COG2206@1|root,COG2206@2|Bacteria,1UI74@1239|Firmicutes,25EC7@186801|Clostridia,267BE@186807|Peptococcaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS3_k127_6484695_0	1121904.ARBP01000042_gene4922	1.844e-123	400.0	COG1247@1|root,COG1247@2|Bacteria,4NIE9@976|Bacteroidetes	976|Bacteroidetes	M	COG NOG10981 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
WZS3_k127_6484695_3	913865.DOT_5576	1.648e-61	213.0	COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,24JIQ@186801|Clostridia,26391@186807|Peptococcaceae	186801|Clostridia	G	PFAM Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WZS3_k127_6484695_5	768704.Desmer_0704	2.133e-19	92.0	2ASZS@1|root,31IFG@2|Bacteria,1V50D@1239|Firmicutes,24PRN@186801|Clostridia,262PV@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_648535_4	1128398.Curi_c20780	6.464e-36	144.0	COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,2682P@186813|unclassified Clostridiales	186801|Clostridia	M	Polysaccharide pyruvyl transferase	csaB	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans
WZS3_k127_648535_3	293826.Amet_4139	4.032e-78	268.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,24AQ3@186801|Clostridia,36E8D@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid	tagA	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB,PS_pyruv_trans
WZS3_k127_648535_2	748727.CLJU_c28540	1.056e-101	343.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,36DPA@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
WZS3_k127_648535_0	350688.Clos_1728	4.565e-244	779.0	COG1067@1|root,COG1067@2|Bacteria,1TQT5@1239|Firmicutes,248NE@186801|Clostridia,36E00@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
WZS3_k127_648535_5	756499.Desde_1315	8.018e-27	112.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,26269@186807|Peptococcaceae	186801|Clostridia	H	PFAM 5-formyltetrahydrofolate cyclo-ligase	yqgN	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
WZS3_k127_648535_7	138119.DSY3972	6.646e-09	60.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,26269@186807|Peptococcaceae	186801|Clostridia	H	PFAM 5-formyltetrahydrofolate cyclo-ligase	yqgN	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
WZS3_k127_648535_1	1304284.L21TH_2461	8.66e-107	350.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,36DHJ@31979|Clostridiaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WZS3_k127_648535_6	1511.CLOST_2084	6.324e-18	86.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,25TA3@186804|Peptostreptococcaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
WZS3_k127_6488221_0	1347392.CCEZ01000016_gene2909	2.201e-172	547.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,36DMT@31979|Clostridiaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS3_k127_6488221_3	293826.Amet_1073	8.717e-66	231.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,36EDR@31979|Clostridiaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
WZS3_k127_6488221_2	411902.CLOBOL_02487	6.13e-66	229.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,21YBH@1506553|Lachnoclostridium	186801|Clostridia	G	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
WZS3_k127_6488221_1	646529.Desaci_2756	4.846e-108	353.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,260W6@186807|Peptococcaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
WZS3_k127_6519547_5	385682.AFSL01000055_gene405	9.893e-38	147.0	COG1237@1|root,COG1237@2|Bacteria,4NQY7@976|Bacteroidetes,2G363@200643|Bacteroidia,3XK3D@558415|Marinilabiliaceae	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WZS3_k127_6519547_10	562743.JH976436_gene2460	3.407e-15	78.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli	91061|Bacilli	G	phosphocarrier protein Hpr	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
WZS3_k127_6519547_11	756499.Desde_0837	6.35e-14	79.0	2E41I@1|root,32YY5@2|Bacteria,1VVZK@1239|Firmicutes,250RQ@186801|Clostridia,265ER@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6519547_4	1499683.CCFF01000014_gene3812	3.296e-76	265.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
WZS3_k127_6519547_3	318464.IO99_12650	2.419e-85	293.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36F10@31979|Clostridiaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WZS3_k127_6519547_2	1449050.JNLE01000005_gene3971	1.449e-109	359.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,36F3J@31979|Clostridiaceae	186801|Clostridia	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
WZS3_k127_6519547_0	1121289.JHVL01000015_gene2707	1.211e-174	556.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WZS3_k127_6519547_9	1294142.CINTURNW_1114	2.731e-23	101.0	2E34K@1|root,32Y4P@2|Bacteria,1VEWQ@1239|Firmicutes,24QJP@186801|Clostridia,36N03@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6519547_1	871963.Desdi_0931	2.472e-162	520.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,264KY@186807|Peptococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WZS3_k127_6519547_8	1274374.CBLK010000064_gene861	6.552e-29	130.0	COG0584@1|root,COG0584@2|Bacteria,1V6FX@1239|Firmicutes,4HWQD@91061|Bacilli,26TWI@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
WZS3_k127_6519547_12	1511.CLOST_2353	1.192e-11	70.0	2D61I@1|root,32TKA@2|Bacteria,1VB5H@1239|Firmicutes,24NZW@186801|Clostridia,25U2C@186804|Peptostreptococcaceae	186801|Clostridia	N	TIGRFAM flagellar operon protein	yvyF	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6519547_6	880073.Calab_0529	1.444e-31	135.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,2NRCG@2323|unclassified Bacteria	2|Bacteria	E	Peptidase family M28	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	iAF987.Gmet_0348	Cofac_haem_bdg,PA,PDZ_2,Peptidase_M1,Peptidase_M28,Trypsin_2
WZS3_k127_6519547_7	1347087.CBYO010000022_gene3809	3.213e-29	120.0	COG0454@1|root,COG0456@2|Bacteria,1V3K1@1239|Firmicutes,4IUBH@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6537624_1	562982.HMPREF0432_00988	1.161e-11	66.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli,3WDX1@539002|Bacillales incertae sedis	91061|Bacilli	G	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
WZS3_k127_6537624_0	1128398.Curi_c29580	1.546e-118	400.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,269Z9@186813|unclassified Clostridiales	186801|Clostridia	M	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
WZS3_k127_6545197_2	1499684.CCNP01000018_gene960	8.583e-120	391.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,36DIN@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
WZS3_k127_6545197_0	1121324.CLIT_2c00230	2.187e-225	714.0	COG1835@1|root,COG1835@2|Bacteria,1V0J2@1239|Firmicutes	1239|Firmicutes	I	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
WZS3_k127_6545197_3	525255.HMPREF0077_1021	8.106e-64	225.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,22HDZ@1570339|Peptoniphilaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
WZS3_k127_6545197_1	1286171.EAL2_808p02630	2.068e-155	497.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,25VGS@186806|Eubacteriaceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
WZS3_k127_6545979_0	1511.CLOST_2403	7.967e-106	350.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,25TIV@186804|Peptostreptococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_6545979_1	1286171.EAL2_c07770	2.107e-105	357.0	arCOG08054@1|root,2Z8AD@2|Bacteria,1TQ1J@1239|Firmicutes,2485U@186801|Clostridia,25WCK@186806|Eubacteriaceae	186801|Clostridia	S	Carbohydrate-binding domain-containing protein Cthe_2159	-	GO:0001871,GO:0003674,GO:0005488,GO:0005509,GO:0030246,GO:0030247,GO:0030248,GO:0043167,GO:0043169,GO:0046872,GO:0048028,GO:2001062	-	-	-	-	-	-	-	-	-	-	Cthe_2159
WZS3_k127_6556313_1	1230342.CTM_17671	3.168e-67	245.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1TR6V@1239|Firmicutes,24AA2@186801|Clostridia,36DWM@31979|Clostridiaceae	186801|Clostridia	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
WZS3_k127_6556313_0	1033810.HLPCO_000996	4.285e-126	405.0	COG2987@1|root,COG2987@2|Bacteria,2NP09@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_0688	Urocanase,Urocanase_C,Urocanase_N
WZS3_k127_6579474_1	350688.Clos_1523	1.993e-174	555.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,36DEW@31979|Clostridiaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
WZS3_k127_6579474_3	1408422.JHYF01000001_gene3023	3.077e-46	171.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,36JKE@31979|Clostridiaceae	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
WZS3_k127_6579474_2	293826.Amet_2676	2.597e-138	449.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,36DXE@31979|Clostridiaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WZS3_k127_6579474_4	596330.HMPREF0628_0697	2.184e-30	121.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,22HUI@1570339|Peptoniphilaceae	186801|Clostridia	K	Protein of unknown function (DUF448)	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
WZS3_k127_6579474_5	1304284.L21TH_1336	6.419e-14	75.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
WZS3_k127_6579474_0	645991.Sgly_2251	2.633e-220	722.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,260ER@186807|Peptococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WZS3_k127_6593640_0	1410668.JNKC01000003_gene475	2.521e-83	283.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,36ES9@31979|Clostridiaceae	186801|Clostridia	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
WZS3_k127_6593640_3	1469948.JPNB01000002_gene3440	6.314e-52	187.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,36ES9@31979|Clostridiaceae	186801|Clostridia	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
WZS3_k127_6593640_1	1286171.EAL2_808p00740	8.919e-69	237.0	COG3945@1|root,COG3945@2|Bacteria,1V3TS@1239|Firmicutes,24HUR@186801|Clostridia,25X34@186806|Eubacteriaceae	186801|Clostridia	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
WZS3_k127_6593640_2	545243.BAEV01000126_gene3459	4.341e-53	194.0	2B9GQ@1|root,322UQ@2|Bacteria,1V748@1239|Firmicutes,24JPR@186801|Clostridia,36F7P@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6593640_4	1294142.CINTURNW_4164	4.673e-22	96.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,36MJC@31979|Clostridiaceae	186801|Clostridia	D	cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
WZS3_k127_6597866_1	509191.AEDB02000073_gene1921	1.366e-87	293.0	COG0188@1|root,COG0188@2|Bacteria,1TPPU@1239|Firmicutes,24CU3@186801|Clostridia,3WG8X@541000|Ruminococcaceae	186801|Clostridia	L	PFAM DNA gyrase topoisomerase IV, subunit A	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WZS3_k127_6597866_0	509191.AEDB02000073_gene1922	8.822e-304	942.0	COG0187@1|root,COG0187@2|Bacteria,1TQ6U@1239|Firmicutes,249NI@186801|Clostridia,3WH8Y@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase	-	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WZS3_k127_6597866_2	1304284.L21TH_1389	6.437e-63	226.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia,36ECN@31979|Clostridiaceae	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
WZS3_k127_6598791_0	1145276.T479_23435	1.648e-133	441.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,4I2NY@91061|Bacilli,3IZJI@400634|Lysinibacillus	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase,dCache_1
WZS3_k127_6615308_1	1321778.HMPREF1982_01292	2.911e-115	400.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,2688X@186813|unclassified Clostridiales	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
WZS3_k127_6615308_0	580331.Thit_1247	2.006e-119	390.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,42EWC@68295|Thermoanaerobacterales	186801|Clostridia	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WZS3_k127_6630627_1	1121324.CLIT_13c02010	2.898e-48	176.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,25REQ@186804|Peptostreptococcaceae	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS3_k127_6630627_0	293826.Amet_4088	6.731e-102	340.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,36EVX@31979|Clostridiaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
WZS3_k127_6630627_2	1286171.EAL2_808p06880	6.143e-08	59.0	COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,24A5K@186801|Clostridia	186801|Clostridia	S	solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
WZS3_k127_6661543_1	610130.Closa_2821	1.014e-97	326.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia,21YT1@1506553|Lachnoclostridium	186801|Clostridia	S	AI-2E family transporter	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS3_k127_6661543_0	1408823.AXUS01000031_gene1622	1.173e-175	563.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,25R5Z@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
WZS3_k127_6661543_2	742765.HMPREF9457_00177	2.697e-65	228.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,27VF9@189330|Dorea	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WZS3_k127_6662795_0	350688.Clos_2290	1.272e-135	455.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,36E2W@31979|Clostridiaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WZS3_k127_6662795_1	536227.CcarbDRAFT_0522	1.505e-69	244.0	COG1218@1|root,COG1218@2|Bacteria,1UKYG@1239|Firmicutes,25G6R@186801|Clostridia	186801|Clostridia	P	Inositol monophosphatase family	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
WZS3_k127_6662795_2	44251.PDUR_05915	6.347e-12	68.0	COG1011@1|root,COG1011@2|Bacteria,1TRQ6@1239|Firmicutes,4HKAS@91061|Bacilli,26UF1@186822|Paenibacillaceae	91061|Bacilli	S	2-haloalkanoic acid dehalogenase	yfnB	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
WZS3_k127_6671352_0	994573.T472_0208580	2.08e-152	499.0	COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,248P6@186801|Clostridia,36FST@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
WZS3_k127_6681488_4	1304284.L21TH_1400	0.0002103	45.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,36DDX@31979|Clostridiaceae	186801|Clostridia	M	Phosphoglycerol transferase and related proteins,, alkaline phosphatase superfamily	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
WZS3_k127_6681488_3	509191.AEDB02000093_gene3448	6.246e-24	107.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,3WPDC@541000|Ruminococcaceae	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
WZS3_k127_6681488_1	293826.Amet_3152	1.263e-50	192.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,24JM4@186801|Clostridia,36J6T@31979|Clostridiaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WZS3_k127_6681488_2	293826.Amet_3151	4.447e-42	158.0	COG1846@1|root,COG1846@2|Bacteria,1VACT@1239|Firmicutes,24RC1@186801|Clostridia,36M18@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_6681488_0	1408422.JHYF01000002_gene2291	1.693e-71	272.0	COG2199@1|root,COG2203@1|root,COG3899@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,36E8P@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GGDEF,Pkinase,TPR_12,TPR_8
WZS3_k127_6688679_1	483218.BACPEC_00987	1.051e-11	67.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,2686N@186813|unclassified Clostridiales	186801|Clostridia	F	Phosphohydrolase-associated domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
WZS3_k127_6688679_0	935948.KE386493_gene2425	6.713e-163	520.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,42F5B@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WZS3_k127_6712412_4	1408422.JHYF01000016_gene127	3.94e-12	66.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,36WSB@31979|Clostridiaceae	186801|Clostridia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WZS3_k127_6712412_2	1408422.JHYF01000016_gene126	2.027e-57	205.0	COG1014@1|root,COG1014@2|Bacteria,1V3RG@1239|Firmicutes,24I3Y@186801|Clostridia,36IU6@31979|Clostridiaceae	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WZS3_k127_6712412_0	2325.TKV_c12620	4.882e-84	287.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,42ERV@68295|Thermoanaerobacterales	186801|Clostridia	K	transcriptional regulator (RpiR family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
WZS3_k127_6712412_1	469616.FMAG_00128	1.86e-60	215.0	COG0283@1|root,COG0283@2|Bacteria,379G2@32066|Fusobacteria	32066|Fusobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WZS3_k127_6712412_3	293826.Amet_2626	4.617e-32	130.0	COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,25B02@186801|Clostridia,36W9A@31979|Clostridiaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
WZS3_k127_6722987_1	293826.Amet_2318	1.133e-62	218.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,36DCQ@31979|Clostridiaceae	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
WZS3_k127_6722987_0	1294142.CINTURNW_3051	3.253e-67	231.0	COG0225@1|root,COG0225@2|Bacteria,1TQ3E@1239|Firmicutes,247UT@186801|Clostridia,36IWX@31979|Clostridiaceae	186801|Clostridia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
WZS3_k127_6722987_2	1094508.Tsac_1611	3.88e-55	199.0	COG1878@1|root,COG1878@2|Bacteria,1UFUJ@1239|Firmicutes,24HGD@186801|Clostridia,42F34@68295|Thermoanaerobacterales	186801|Clostridia	S	cyclase family	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
WZS3_k127_6722987_3	935948.KE386494_gene353	2.494e-23	102.0	COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,24939@186801|Clostridia,42FRW@68295|Thermoanaerobacterales	186801|Clostridia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
WZS3_k127_6726406_1	1121289.JHVL01000001_gene1877	9.184e-97	319.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,36DBK@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
WZS3_k127_6726406_2	1304284.L21TH_0016	1.141e-68	235.0	COG1607@1|root,COG1607@2|Bacteria,1V3ZQ@1239|Firmicutes,24HF8@186801|Clostridia,36IT9@31979|Clostridiaceae	186801|Clostridia	I	Thioesterase superfamily	kal	-	4.3.1.14	ko:K18014	ko00310,map00310	-	R03030	RC00833	ko00000,ko00001,ko01000	-	-	-	4HBT
WZS3_k127_6726406_0	293826.Amet_0318	1.723e-143	459.0	COG3246@1|root,COG3246@2|Bacteria,1TQNV@1239|Firmicutes,248TX@186801|Clostridia,36DPI@31979|Clostridiaceae	186801|Clostridia	S	beta-keto acid cleavage enzyme	kce	-	2.3.1.247	ko:K18013	ko00310,map00310	-	R10564	RC02728,RC03199	ko00000,ko00001,ko01000	-	-	-	BKACE
WZS3_k127_6726406_3	1321815.HMPREF9193_00998	9.38e-07	57.0	COG1305@1|root,COG1305@2|Bacteria,2J57S@203691|Spirochaetes	203691|Spirochaetes	E	IPT TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
WZS3_k127_6726480_3	1408254.T458_12100	2.568e-33	130.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli,26RW4@186822|Paenibacillaceae	91061|Bacilli	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
WZS3_k127_6726480_2	666686.B1NLA3E_02435	5.598e-45	169.0	COG3797@1|root,COG3797@2|Bacteria,1V426@1239|Firmicutes,4IR4E@91061|Bacilli,1ZRRK@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
WZS3_k127_6726480_1	1196322.A370_03213	2.899e-48	176.0	arCOG06631@1|root,32RY6@2|Bacteria,1V8RP@1239|Firmicutes,24MV5@186801|Clostridia,36KXB@31979|Clostridiaceae	186801|Clostridia	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_6726480_0	1230342.CTM_00720	8.941e-60	210.0	COG3382@1|root,COG3382@2|Bacteria,1TT38@1239|Firmicutes,248VG@186801|Clostridia,36GA1@31979|Clostridiaceae	186801|Clostridia	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
WZS3_k127_6741303_1	224324.aq_1272	1.83e-21	97.0	COG0799@1|root,COG0799@2|Bacteria,2G49D@200783|Aquificae	200783|Aquificae	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WZS3_k127_6741303_0	642492.Clole_2112	7.521e-83	289.0	COG1057@1|root,COG1713@1|root,COG1057@2|Bacteria,COG1713@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WZS3_k127_6748274_1	195103.CPF_2634	5.869e-98	325.0	COG2227@1|root,COG2227@2|Bacteria,1TSTX@1239|Firmicutes,24D4E@186801|Clostridia,36FZJ@31979|Clostridiaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS3_k127_6748274_0	1408422.JHYF01000008_gene3747	3.849e-280	869.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,36DUQ@31979|Clostridiaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
WZS3_k127_6748274_3	293826.Amet_0518	7.279e-58	213.0	COG2177@1|root,COG2177@2|Bacteria,1V9I3@1239|Firmicutes,24GNH@186801|Clostridia,36QEB@31979|Clostridiaceae	186801|Clostridia	D	FtsX-like permease family	-	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
WZS3_k127_6748274_2	293826.Amet_0519	1.898e-71	248.0	COG2884@1|root,COG2884@2|Bacteria,1VT39@1239|Firmicutes,24E18@186801|Clostridia,36RCI@31979|Clostridiaceae	186801|Clostridia	D	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WZS3_k127_6748274_4	293826.Amet_0520	6.387e-26	112.0	COG4942@1|root,COG4942@2|Bacteria,1VR95@1239|Firmicutes,24HB3@186801|Clostridia,36QKV@31979|Clostridiaceae	186801|Clostridia	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6753742_3	1304866.K413DRAFT_0273	8.464e-55	194.0	COG1741@1|root,COG1741@2|Bacteria,1TQDV@1239|Firmicutes,2497R@186801|Clostridia,36G31@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WZS3_k127_6753742_0	1499680.CCFE01000031_gene3734	1.326e-138	445.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli,1ZAUV@1386|Bacillus	91061|Bacilli	K	AraC family transcriptional regulator	ydeE	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
WZS3_k127_6753742_1	1408422.JHYF01000008_gene3690	1.318e-65	228.0	2EF1Q@1|root,338UT@2|Bacteria,1VUCG@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6753742_2	350688.Clos_1299	3.252e-56	199.0	COG0731@1|root,COG0731@2|Bacteria,1V1JJ@1239|Firmicutes,25DKG@186801|Clostridia,36FHY@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
WZS3_k127_6760140_0	1499689.CCNN01000007_gene1995	3.866e-43	171.0	COG3393@1|root,COG3393@2|Bacteria,1VBKV@1239|Firmicutes,24M6Z@186801|Clostridia,36P7D@31979|Clostridiaceae	186801|Clostridia	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
WZS3_k127_6760140_2	1526927.Plano_1530	5.341e-24	113.0	COG3437@1|root,COG3437@2|Bacteria,1UNCG@1239|Firmicutes,4HDU3@91061|Bacilli,26CX3@186818|Planococcaceae	91061|Bacilli	KT	5TMR of 5TMR-LYT	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GGDEF
WZS3_k127_6760140_1	1232449.BAHV02000020_gene1359	3.04e-31	126.0	COG0793@1|root,COG0793@2|Bacteria,1UYV5@1239|Firmicutes,24B0A@186801|Clostridia,26BHR@186813|unclassified Clostridiales	186801|Clostridia	M	Belongs to the peptidase S41A family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
WZS3_k127_6777969_3	1449126.JQKL01000025_gene2410	1.293e-114	390.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,26AF8@186813|unclassified Clostridiales	186801|Clostridia	G	Periplasmic binding protein-like domain	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
WZS3_k127_6777969_2	1511.CLOST_2410	3.829e-128	429.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,25QU7@186804|Peptostreptococcaceae	186801|Clostridia	G	Periplasmic binding protein domain	rbsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
WZS3_k127_6777969_1	1511.CLOST_2411	1.925e-131	426.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,25QDR@186804|Peptostreptococcaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	rbsC	-	-	ko:K10440,ko:K17214	ko02010,map02010	M00212,M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
WZS3_k127_6777969_0	1511.CLOST_2412	1.492e-223	703.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,25QRU@186804|Peptostreptococcaceae	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K02056,ko:K10441,ko:K10542,ko:K10548	ko02010,map02010	M00212,M00214,M00216,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3,3.A.1.2.5	-	-	ABC_tran
WZS3_k127_6777969_5	1511.CLOST_2413	3.147e-45	167.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,24MPJ@186801|Clostridia,25RRD@186804|Peptostreptococcaceae	186801|Clostridia	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
WZS3_k127_6777969_4	1511.CLOST_2414	4.856e-77	263.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,25RF7@186804|Peptostreptococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WZS3_k127_6818214_2	742741.HMPREF9475_01895	1.429e-23	107.0	2EARC@1|root,334TI@2|Bacteria,1VIGN@1239|Firmicutes,24SNE@186801|Clostridia,22369@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
WZS3_k127_6818214_1	857293.CAAU_2168	1.205e-52	197.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,247S9@186801|Clostridia,36FAU@31979|Clostridiaceae	186801|Clostridia	H	Lipoate-protein ligase	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
WZS3_k127_6818214_0	865861.AZSU01000006_gene1325	8.759e-136	439.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia,36E7U@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
WZS3_k127_682149_2	935948.KE386495_gene2231	8.019e-07	51.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,24QIM@186801|Clostridia,42GUT@68295|Thermoanaerobacterales	186801|Clostridia	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
WZS3_k127_682149_0	350688.Clos_1552	9.163e-94	316.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,36DRA@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WZS3_k127_682149_1	1196322.A370_03231	4.916e-47	183.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,36EVN@31979|Clostridiaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WZS3_k127_6825925_5	398512.JQKC01000001_gene2379	1.475e-50	182.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS3_k127_6825925_6	1286171.EAL2_c04320	5.785e-50	183.0	2DRGB@1|root,32UR1@2|Bacteria,1V5TU@1239|Firmicutes,24IXW@186801|Clostridia	186801|Clostridia	-	-	hymD	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
WZS3_k127_6825925_1	1348908.KI518582_gene2389	8.417e-141	470.0	COG0572@1|root,COG5650@1|root,COG0572@2|Bacteria,COG5650@2|Bacteria,1V0KA@1239|Firmicutes,4HXDX@91061|Bacilli	91061|Bacilli	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
WZS3_k127_6825925_4	1121875.KB907551_gene1095	1.803e-53	196.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WZS3_k127_6825925_7	1121875.KB907551_gene1096	3.176e-42	169.0	COG3347@1|root,COG3347@2|Bacteria,4NEM0@976|Bacteroidetes	976|Bacteroidetes	IQ	Rhamnulose-1-phosphate aldolase alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
WZS3_k127_6825925_0	866895.HBHAL_1982	1.824e-195	624.0	COG1208@1|root,COG1208@2|Bacteria,1UKM9@1239|Firmicutes	1239|Firmicutes	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
WZS3_k127_6825925_8	1196322.A370_05531	6.816e-22	100.0	COG2246@1|root,COG2246@2|Bacteria,1VJZ2@1239|Firmicutes	1239|Firmicutes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WZS3_k127_6825925_2	1121875.KB907551_gene1100	1.077e-88	298.0	COG1216@1|root,COG1216@2|Bacteria,4P3QR@976|Bacteroidetes	976|Bacteroidetes	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
WZS3_k127_6825925_3	582402.Hbal_3208	3.87e-55	201.0	COG0584@1|root,COG0584@2|Bacteria,1RKFF@1224|Proteobacteria,2USXH@28211|Alphaproteobacteria,43Z23@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6829424_2	445335.CBN_2235	2.804e-32	129.0	COG0437@1|root,COG0716@1|root,COG0437@2|Bacteria,COG0716@2|Bacteria,1U9MX@1239|Firmicutes,248ES@186801|Clostridia,36F6K@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_18,Fer4_4,Flavodoxin_5
WZS3_k127_6829424_0	1408473.JHXO01000005_gene1726	3.762e-76	259.0	COG2818@1|root,COG2818@2|Bacteria,4NGRC@976|Bacteroidetes,2FN7E@200643|Bacteroidia	976|Bacteroidetes	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
WZS3_k127_751_0	941824.TCEL_01258	8.064e-217	696.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,36ER3@31979|Clostridiaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
WZS3_k127_751_1	1304284.L21TH_2579	1.643e-29	127.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,36IPK@31979|Clostridiaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
WZS3_k127_751_2	697281.Mahau_2352	1.451e-23	105.0	2D61I@1|root,32TKA@2|Bacteria,1VB5H@1239|Firmicutes,24NZW@186801|Clostridia,42GRU@68295|Thermoanaerobacterales	186801|Clostridia	N	TIGRFAM flagellar operon protein	yvyF	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_751_3	1121289.JHVL01000041_gene3049	3.384e-12	70.0	COG2747@1|root,COG2747@2|Bacteria,1VKDG@1239|Firmicutes,24UWF@186801|Clostridia,36NY8@31979|Clostridiaceae	186801|Clostridia	KNU	Anti-sigma-28 factor, FlgM	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
WZS3_k127_75950_2	509191.AEDB02000002_gene1228	1.178e-39	152.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia,3WNGZ@541000|Ruminococcaceae	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS3_k127_75950_0	1304284.L21TH_2042	1.641e-99	338.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,36ECQ@31979|Clostridiaceae	186801|Clostridia	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS3_k127_75950_1	293826.Amet_2206	1.314e-63	225.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,36DP3@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
WZS3_k127_760672_2	463191.SSEG_00725	2.525e-06	49.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria	201174|Actinobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
WZS3_k127_760672_1	1345695.CLSA_c38790	2.564e-117	387.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,36E6Q@31979|Clostridiaceae	186801|Clostridia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WZS3_k127_760672_0	931626.Awo_c07090	6.408e-150	501.0	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes	2|Bacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,HisKA_7TM,PAS,PAS_3,PAS_4,PAS_8,PAS_9
WZS3_k127_793566_1	545695.TREAZ_2097	4.621e-37	143.0	28M3X@1|root,2ZAHZ@2|Bacteria,2JB7I@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_793566_2	315749.Bcer98_2302	2.518e-14	75.0	COG5460@1|root,COG5460@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
WZS3_k127_793566_0	767817.Desgi_0620	4.24e-56	200.0	COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,24JBS@186801|Clostridia,26247@186807|Peptococcaceae	186801|Clostridia	S	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
WZS3_k127_808564_4	1211817.CCAT010000016_gene3795	1.336e-64	230.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,36F3P@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, LysR family	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WZS3_k127_808564_1	457396.CSBG_00634	2.963e-114	376.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,36EJD@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS3_k127_808564_3	1391647.AVSV01000025_gene560	6.173e-68	237.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,36EH9@31979|Clostridiaceae	186801|Clostridia	E	Serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
WZS3_k127_808564_2	536227.CcarbDRAFT_2538	7.971e-82	280.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,36F9G@31979|Clostridiaceae	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
WZS3_k127_808564_5	1211817.CCAT010000067_gene476	9.306e-54	199.0	COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,247ZD@186801|Clostridia,36U61@31979|Clostridiaceae	186801|Clostridia	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
WZS3_k127_808564_6	97138.C820_01252	1.161e-45	171.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,36II2@31979|Clostridiaceae	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
WZS3_k127_808564_9	796940.HMPREF9628_01083	0.0002547	45.0	COG0316@1|root,COG0316@2|Bacteria,1VGGP@1239|Firmicutes,24HQ7@186801|Clostridia,25RV5@186804|Peptostreptococcaceae	186801|Clostridia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
WZS3_k127_808564_7	1511.CLOST_0849	9.721e-26	108.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia,25RSV@186804|Peptostreptococcaceae	186801|Clostridia	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
WZS3_k127_808564_0	580327.Tthe_0249	3.675e-314	982.0	COG0425@1|root,COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0425@2|Bacteria,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,42EW6@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
WZS3_k127_808564_8	935948.KE386494_gene548	2.53e-20	93.0	COG1937@1|root,COG1937@2|Bacteria,1UEIT@1239|Firmicutes,25JGH@186801|Clostridia,42H54@68295|Thermoanaerobacterales	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WZS3_k127_81460_1	272563.CD630_27460	2.188e-133	449.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25QXQ@186804|Peptostreptococcaceae	186801|Clostridia	L	exonuclease	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,ssDNA-exonuc_C
WZS3_k127_81460_2	857293.CAAU_2600	1.909e-67	233.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,36HZI@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WZS3_k127_81460_0	1347392.CCEZ01000043_gene562	1.894e-148	478.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,36EH5@31979|Clostridiaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
WZS3_k127_862639_2	1304880.JAGB01000002_gene2181	1.764e-56	210.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia	186801|Clostridia	T	Histidine kinase- DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_862639_1	1122927.KB895441_gene2184	1.139e-67	237.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,4HAX9@91061|Bacilli,26T4W@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_862639_0	313606.M23134_07181	2.492e-101	340.0	COG1181@1|root,COG1181@2|Bacteria,4NE9P@976|Bacteroidetes,47M8U@768503|Cytophagia	976|Bacteroidetes	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WZS3_k127_872160_0	1280673.AUJJ01000003_gene131	5.275e-173	556.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,4BWZK@830|Butyrivibrio	186801|Clostridia	J	tRNA synthetases class I (C) catalytic domain	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
WZS3_k127_872160_1	871968.DESME_01935	1.086e-92	313.0	COG0697@1|root,COG0697@2|Bacteria,1V009@1239|Firmicutes,24DF1@186801|Clostridia,264VJ@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_890774_0	344747.PM8797T_27914	2.599e-235	747.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2IXGZ@203682|Planctomycetes	203682|Planctomycetes	M	cyanophycin synthetase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS3_k127_890774_1	1089552.KI911559_gene2231	7.85e-67	238.0	COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,2U4I8@28211|Alphaproteobacteria,2JVEW@204441|Rhodospirillales	204441|Rhodospirillales	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
WZS3_k127_890774_4	572479.Hprae_0388	1.325e-19	90.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia	186801|Clostridia	K	Transcriptional	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_890774_2	1487923.DP73_12615	7.929e-65	224.0	COG3832@1|root,COG3832@2|Bacteria,1VW43@1239|Firmicutes,250QB@186801|Clostridia	186801|Clostridia	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_890774_3	1307437.J139_00650	1.173e-37	146.0	COG5001@1|root,COG5001@2|Bacteria,1MUNI@1224|Proteobacteria,1RRUX@1236|Gammaproteobacteria,2Q0PF@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	T	COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,EAL,GGDEF,Response_reg
WZS3_k127_933227_3	1443125.Z962_01445	2.497e-31	124.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,36DXT@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_933227_2	1031288.AXAA01000015_gene282	7.737e-128	413.0	COG1586@1|root,COG1586@2|Bacteria,1TQ7S@1239|Firmicutes,2480M@186801|Clostridia,36ET4@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
WZS3_k127_933227_0	1304284.L21TH_0249	1.145e-177	569.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,36DPH@31979|Clostridiaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
WZS3_k127_933227_1	1033810.HLPCO_001320	1.922e-146	467.0	COG0421@1|root,COG0421@2|Bacteria,2NPMY@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
WZS3_k127_945965_1	1449335.JQLG01000004_gene1683	3.285e-100	327.0	arCOG06481@1|root,2ZB4E@2|Bacteria,1V0ND@1239|Firmicutes,4HFG5@91061|Bacilli,27FK3@186828|Carnobacteriaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_945965_0	1009370.ALO_00705	4.607e-135	437.0	COG0044@1|root,COG0044@2|Bacteria,1TPI6@1239|Firmicutes,4H9F2@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS3_k127_955688_2	1511.CLOST_2035	6.907e-136	440.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia	186801|Clostridia	E	Belongs to the arginase family	hutG	-	3.5.3.8	ko:K01479	ko00340,ko01100,map00340,map01100	M00045	R02285	RC00221,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WZS3_k127_955688_1	428125.CLOLEP_02149	6.391e-168	540.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,3WGCT@541000|Ruminococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WZS3_k127_955688_0	1511.CLOST_0019	5.054e-195	619.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,25QZW@186804|Peptostreptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS3_k127_955688_3	1511.CLOST_0018	1.486e-76	262.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25QPR@186804|Peptostreptococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WZS3_k127_993422_0	1408422.JHYF01000008_gene3632	3.518e-123	403.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,36E7X@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
## 1761 queries scanned
## Total time (seconds): 9.94925570487976
## Rate: 177.00 q/s