## Tue Nov 12 13:11:04 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/WX/WZS3_bin.19.fa -m mmseqs --itype genome -o WZS3_bin.19 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/WZS3_bin.19 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
WZS3_k127_1000165_2	428127.EUBDOL_00911	2.09e-22	100.0	COG1475@1|root,COG1475@2|Bacteria,1TP0I@1239|Firmicutes,3VNXN@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WZS3_k127_1000165_0	545696.HOLDEFILI_00900	2.029e-130	420.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,3VPBB@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Sporulation initiation inhibitor protein Soj	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WZS3_k127_1000165_1	545696.HOLDEFILI_00899	1.359e-22	98.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,3VPFM@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	HTH_3,ParBc
WZS3_k127_1005392_3	1211819.CALK01000047_gene1821	1.315e-81	276.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,3VPI4@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
WZS3_k127_1005392_8	1211819.CALK01000047_gene1822	8.199e-37	141.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,3VRDE@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
WZS3_k127_1005392_0	545696.HOLDEFILI_01365	2.934e-149	475.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,3VP5M@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
WZS3_k127_1005392_6	428127.EUBDOL_00561	1.489e-49	177.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,3VQW8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
WZS3_k127_1005392_7	1211819.CALK01000047_gene1825	1.352e-48	175.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,3VQU3@526524|Erysipelotrichia	526524|Erysipelotrichia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
WZS3_k127_1005392_1	1232449.BAHV02000010_gene2452	3.766e-105	347.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,2680N@186813|unclassified Clostridiales	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
WZS3_k127_1005392_4	1211819.CALK01000047_gene1827	1.454e-73	249.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,3VQ9M@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
WZS3_k127_1005392_11	1211819.CALK01000047_gene1828	3.953e-21	94.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,3VRP2@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
WZS3_k127_1005392_9	545696.HOLDEFILI_01371	2.829e-33	130.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,3VR8U@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
WZS3_k127_1005392_5	1121874.KB892378_gene476	4.526e-62	214.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,3VQJP@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
WZS3_k127_1005392_10	658659.HMPREF0983_02739	7.006e-28	115.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,3VRDS@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
WZS3_k127_1005392_2	877415.JNJQ01000007_gene803	3.035e-82	275.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,3VPJT@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
WZS3_k127_1033240_4	713605.ADHG01000002_gene1061	4.934e-05	48.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli,3F505@33958|Lactobacillaceae	91061|Bacilli	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
WZS3_k127_1033240_2	545696.HOLDEFILI_01853	1.632e-53	192.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,3VQR5@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
WZS3_k127_1033240_1	1211819.CALK01000009_gene2773	7.865e-126	411.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,3VPC1@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HTH_DeoR,HrcA,HrcA_DNA-bdg
WZS3_k127_1033240_3	545696.HOLDEFILI_01858	7.061e-45	169.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,3VQK4@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	-	-	-	-	-	-	-	-	-	GrpE
WZS3_k127_1033240_0	552396.HMPREF0863_01680	3.473e-188	592.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,3VPEP@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WZS3_k127_1045043_2	1211844.CBLM010000077_gene2489	1.806e-43	166.0	COG0561@1|root,COG0561@2|Bacteria,1V28T@1239|Firmicutes,3VQD8@526524|Erysipelotrichia	526524|Erysipelotrichia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_1045043_1	655812.HMPREF0061_1467	3.084e-47	178.0	COG5522@1|root,COG5522@2|Bacteria,1UPRP@1239|Firmicutes,4IV9N@91061|Bacilli	91061|Bacilli	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
WZS3_k127_1045043_0	552396.HMPREF0863_01877	2.687e-69	241.0	COG0444@1|root,COG0444@2|Bacteria,1TS8Q@1239|Firmicutes,3VP9N@526524|Erysipelotrichia	526524|Erysipelotrichia	EP	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_108460_2	1121874.KB892377_gene1348	6.005e-32	126.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,3VP9S@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WZS3_k127_108460_0	1232449.BAHV02000012_gene2292	2.321e-204	644.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,2683X@186813|unclassified Clostridiales	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
WZS3_k127_108460_1	552396.HMPREF0863_00929	1.834e-57	207.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,3VQIU@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
WZS3_k127_108460_4	552396.HMPREF0863_00930	6.832e-15	83.0	2ETHW@1|root,33M1S@2|Bacteria,1VETM@1239|Firmicutes,3VRJE@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_108460_3	169963.lmo1945	2e-25	113.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli,26J2T@186820|Listeriaceae	91061|Bacilli	U	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
WZS3_k127_1122120_0	509191.AEDB02000064_gene551	1.229e-320	994.0	COG0004@1|root,COG0347@1|root,COG0004@2|Bacteria,COG0347@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3WH0N@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the P(II) protein family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
WZS3_k127_1122120_2	1504823.CCMM01000010_gene1325	3.492e-58	211.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	focA	-	-	ko:K02598,ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.2,1.A.16.3	-	-	Form_Nir_trans
WZS3_k127_1122120_1	545696.HOLDEFILI_02183	1.371e-134	442.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,3VP75@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Extracellular, score	ponA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	FIVAR,Transgly,Transpeptidase
WZS3_k127_1131706_3	1449335.JQLG01000004_gene1683	7.224e-46	166.0	arCOG06481@1|root,2ZB4E@2|Bacteria,1V0ND@1239|Firmicutes,4HFG5@91061|Bacilli,27FK3@186828|Carnobacteriaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1131706_0	1226325.HMPREF1548_00101	2.505e-102	351.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36EDE@31979|Clostridiaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_1131706_2	445971.ANASTE_01378	3.592e-57	211.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia,25WYW@186806|Eubacteriaceae	186801|Clostridia	EG	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_1131706_1	580327.Tthe_0640	4.694e-70	248.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,42FY5@68295|Thermoanaerobacterales	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	5.1.1.1	ko:K01775,ko:K02529,ko:K05499	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_116963_0	1121428.DESHY_160079___1	6.519e-215	676.0	COG4865@1|root,COG4865@2|Bacteria,1TS6B@1239|Firmicutes,24AYE@186801|Clostridia,2610W@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate)	glmE	-	5.4.99.1	ko:K19268	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R00262	RC01221	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_asp_mut_E
WZS3_k127_116963_1	748449.Halha_1651	3.408e-118	394.0	COG0849@1|root,COG0849@2|Bacteria,1TQC5@1239|Firmicutes,24BFJ@186801|Clostridia,3WAFS@53433|Halanaerobiales	186801|Clostridia	D	TIGRFAM conserved	mutL2	-	-	-	-	-	-	-	-	-	-	-	MutL
WZS3_k127_116963_2	744872.Spica_1656	1.438e-06	50.0	COG2185@1|root,COG2185@2|Bacteria,2J83G@203691|Spirochaetes	203691|Spirochaetes	I	Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate)	mamA	-	5.4.99.1	ko:K01846	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R00262	RC01221	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
WZS3_k127_1170069_2	1211819.CALK01000012_gene312	2.966e-11	64.0	COG0666@1|root,COG0666@2|Bacteria,1V2DE@1239|Firmicutes,3VP39@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Ankyrin repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_5
WZS3_k127_1170069_1	1211819.CALK01000022_gene1661	7.703e-31	134.0	COG5279@1|root,COG5279@2|Bacteria,1VJSX@1239|Firmicutes	1239|Firmicutes	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WZS3_k127_1170069_0	1121024.AUCD01000070_gene256	3.049e-173	555.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,4HAJJ@91061|Bacilli,27HA8@186828|Carnobacteriaceae	91061|Bacilli	E	Oligoendopeptidase F	pepF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
WZS3_k127_117340_1	350688.Clos_2048	9.49e-137	443.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,36E9C@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_117340_12	350688.Clos_2049	8.567e-23	99.0	COG2608@1|root,COG2608@2|Bacteria,1VG8U@1239|Firmicutes,24TEQ@186801|Clostridia,36NJ2@31979|Clostridiaceae	186801|Clostridia	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
WZS3_k127_117340_3	1123075.AUDP01000022_gene3587	3.295e-80	273.0	COG2267@1|root,COG2267@2|Bacteria,1UHTS@1239|Firmicutes,25EGE@186801|Clostridia,3WRPT@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS3_k127_117340_7	1158604.I591_00819	1.047e-45	167.0	COG4898@1|root,COG4898@2|Bacteria,1V6U6@1239|Firmicutes,4HH1D@91061|Bacilli,4B33U@81852|Enterococcaceae	91061|Bacilli	S	Uncharacterized protein conserved in bacteria (DUF2200)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
WZS3_k127_117340_6	1105031.HMPREF1141_2341	2.441e-52	189.0	COG2153@1|root,COG2153@2|Bacteria,1VAJY@1239|Firmicutes,24JG3@186801|Clostridia,36JM2@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
WZS3_k127_117340_4	1235797.C816_03459	5.956e-79	269.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,2N755@216572|Oscillospiraceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WZS3_k127_117340_9	1235797.C816_03459	1.594e-36	139.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,2N755@216572|Oscillospiraceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
WZS3_k127_117340_11	649747.HMPREF0083_04180	1.951e-24	116.0	COG0477@1|root,COG2814@2|Bacteria,1TQHD@1239|Firmicutes,4HBCZ@91061|Bacilli,26QDE@186822|Paenibacillaceae	91061|Bacilli	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS3_k127_117340_0	1278311.AUAL01000038_gene200	1.598e-145	467.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	mhqA	-	3.4.21.26	ko:K01322,ko:K15975	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Glyoxalase
WZS3_k127_117340_10	1278304.JAFR01000007_gene204	3.2e-34	135.0	COG1846@1|root,COG1846@2|Bacteria,3WU7Y@544448|Tenericutes	544448|Tenericutes	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
WZS3_k127_117340_5	1121929.KB898680_gene1685	1.674e-76	260.0	COG0400@1|root,COG0400@2|Bacteria,1TPBY@1239|Firmicutes,4HB45@91061|Bacilli,4717H@74385|Gracilibacillus	91061|Bacilli	S	Carboxylesterase	yahD	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,DLH
WZS3_k127_117340_2	931626.Awo_c32700	4.893e-115	391.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,25WUV@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
WZS3_k127_117340_8	1121930.AQXG01000001_gene1240	3.716e-42	162.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,1ISXP@117747|Sphingobacteriia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
WZS3_k127_1176393_5	926561.KB900618_gene311	2.713e-08	57.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_1176393_3	1123009.AUID01000028_gene332	1.599e-32	136.0	28M3X@1|root,2ZAHZ@2|Bacteria,1VAMQ@1239|Firmicutes,24EZ1@186801|Clostridia,26CDW@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1176393_2	398512.JQKC01000008_gene939	2.302e-70	245.0	COG0745@1|root,COG0745@2|Bacteria,1U3FH@1239|Firmicutes,248BR@186801|Clostridia,3WN5V@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_1176393_1	357809.Cphy_2122	3.712e-100	342.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,21YQ1@1506553|Lachnoclostridium	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_1176393_4	1033810.HLPCO_000744	7.29e-32	131.0	2DBY6@1|root,2ZBTG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1176393_0	573061.Clocel_3854	1.343e-218	686.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,36ER9@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
WZS3_k127_1179517_2	445972.ANACOL_02336	6.602e-52	187.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3WGFP@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
WZS3_k127_1179517_1	469378.Ccur_08270	2.692e-56	204.0	COG2011@1|root,COG2011@2|Bacteria,2GY65@201174|Actinobacteria,4CVF1@84998|Coriobacteriia	84998|Coriobacteriia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
WZS3_k127_1179517_0	1121335.Clst_0044	4.801e-89	301.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3WH0R@541000|Ruminococcaceae	186801|Clostridia	P	nlpA lipoprotein	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
WZS3_k127_1179932_2	1507.HMPREF0262_01238	5.088e-32	128.0	COG0664@1|root,COG0664@2|Bacteria,1TT3C@1239|Firmicutes,25CJZ@186801|Clostridia,36FW6@31979|Clostridiaceae	186801|Clostridia	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
WZS3_k127_1179932_0	910964.GEAM_0552	5.95e-151	482.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,1RQ1V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the IUNH family	rihB	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	3.2.2.1,3.2.2.8	ko:K01239,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_3298,iECSP_1301.ECSP_3040,iECs_1301.ECs3054,iSFV_1184.SFV_2237,iSF_1195.SF2247,iSFxv_1172.SFxv_2480,iS_1188.S2376,iZ_1308.Z3419	IU_nuc_hydro
WZS3_k127_1179932_3	642492.Clole_0255	3.364e-12	66.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
WZS3_k127_1179932_1	203119.Cthe_1592	1.71e-42	158.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3WGR3@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
WZS3_k127_1217808_3	545696.HOLDEFILI_01585	8.635e-14	71.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,3VNPQ@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	-	-	-	-	-	-	-	-	-	Rnf-Nqr
WZS3_k127_1217808_4	1232449.BAHV02000016_gene1856	2.306e-12	68.0	2DTIK@1|root,33KIC@2|Bacteria,1VPM7@1239|Firmicutes,25563@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1217808_2	1211819.CALK01000013_gene235	4.099e-25	107.0	COG2878@1|root,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,3VR83@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Putative Fe-S cluster	rnfB	-	-	-	-	-	-	-	-	-	-	-	FeS
WZS3_k127_1217808_5	509191.AEDB02000063_gene454	3.416e-06	57.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia,3WPJ0@541000|Ruminococcaceae	186801|Clostridia	U	Chaperone for flagella basal body P-ring formation	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,RcpC,SAF
WZS3_k127_1217808_0	1232449.BAHV02000016_gene1850	2.856e-94	321.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
WZS3_k127_124038_7	1504823.CCMM01000011_gene1414	2.501e-06	53.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yvyE	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF1949,UPF0029
WZS3_k127_124038_1	1121874.KB892378_gene594	7.076e-125	411.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,3VPDZ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
WZS3_k127_124038_3	931626.Awo_c18130	6.219e-94	319.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,25V1R@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,HD_5,Response_reg
WZS3_k127_124038_2	931626.Awo_c18120	7.01e-100	351.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1UYQH@1239|Firmicutes,25BE7@186801|Clostridia,25YVN@186806|Eubacteriaceae	186801|Clostridia	T	PAS fold	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_9
WZS3_k127_124038_5	1211819.CALK01000048_gene1422	3.66e-51	191.0	28TVG@1|root,2ZG2C@2|Bacteria,1V2IF@1239|Firmicutes,3VQBY@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_124038_6	526224.Bmur_0417	4.59e-35	145.0	COG0697@1|root,COG0697@2|Bacteria,2J77Z@203691|Spirochaetes	203691|Spirochaetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_124038_4	1211819.CALK01000048_gene1425	8.86e-76	284.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,3VPIS@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Psort location Cytoplasmic, score	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
WZS3_k127_124038_0	1211819.CALK01000048_gene1426	1.693e-138	466.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,3VPAD@526524|Erysipelotrichia	526524|Erysipelotrichia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WZS3_k127_1267135_2	650150.ERH_1051	2.831e-139	445.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,3VPMP@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WZS3_k127_1267135_1	908340.HMPREF9406_0972	2.385e-211	673.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,36E7X@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
WZS3_k127_1267135_5	1211819.CALK01000001_gene331	1.172e-82	290.0	COG0860@1|root,COG0860@2|Bacteria,1V321@1239|Firmicutes,3VQM0@526524|Erysipelotrichia	526524|Erysipelotrichia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
WZS3_k127_1267135_0	1211819.CALK01000001_gene329	8.533e-241	751.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,3VNWD@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
WZS3_k127_1267135_4	518637.EUBIFOR_02038	3.184e-93	309.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,3VP2Z@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
WZS3_k127_1267135_3	1211819.CALK01000001_gene327	1.7e-124	404.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,3VPN2@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WZS3_k127_1278092_2	545696.HOLDEFILI_02365	7.405e-45	166.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,3VNPU@526524|Erysipelotrichia	526524|Erysipelotrichia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WZS3_k127_1278092_0	1211819.CALK01000056_gene1177	7.543e-104	345.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,3VP4B@526524|Erysipelotrichia	526524|Erysipelotrichia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WZS3_k127_1278092_1	1211819.CALK01000056_gene1176	3.674e-102	338.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,3VNXY@526524|Erysipelotrichia	526524|Erysipelotrichia	P	cobalt transport	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
WZS3_k127_1278092_3	1399115.U719_00645	1.783e-44	167.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli,3WER2@539002|Bacillales incertae sedis	91061|Bacilli	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WZS3_k127_1292547_1	1507.HMPREF0262_01311	2.356e-14	79.0	COG0524@1|root,COG0524@2|Bacteria,1V441@1239|Firmicutes,24I7R@186801|Clostridia,36NW8@31979|Clostridiaceae	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WZS3_k127_1292547_0	1121874.KB892379_gene353	2.334e-30	126.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,3VQ2A@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Lactonase, 7-bladed beta-propeller	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
WZS3_k127_1300889_0	931626.Awo_c33740	5.17e-97	324.0	COG1541@1|root,COG1541@2|Bacteria,1UY8F@1239|Firmicutes,25NRK@186801|Clostridia,25Y1D@186806|Eubacteriaceae	186801|Clostridia	H	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
WZS3_k127_1300889_1	1541960.KQ78_00378	8.592e-90	321.0	COG3437@1|root,COG3437@2|Bacteria,3WU98@544448|Tenericutes	2|Bacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,GAF_2,GGDEF,HD,HD_5,HisKA_7TM
WZS3_k127_1317877_6	665956.HMPREF1032_03991	1.088e-12	70.0	COG1670@1|root,COG1670@2|Bacteria,1UI20@1239|Firmicutes,24HRV@186801|Clostridia	186801|Clostridia	J	Acetyltransferase GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
WZS3_k127_1317877_0	428127.EUBDOL_00085	1.867e-126	411.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,3VPBC@526524|Erysipelotrichia	526524|Erysipelotrichia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WZS3_k127_1317877_5	545696.HOLDEFILI_03799	1.193e-25	111.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,3VQSA@526524|Erysipelotrichia	526524|Erysipelotrichia	OU	COG COG1585 Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
WZS3_k127_1317877_3	138119.DSY0347	5.185e-37	141.0	2EG8Z@1|root,32UBD@2|Bacteria,1VBQD@1239|Firmicutes,24NWB@186801|Clostridia,265M4@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1317877_7	504728.K649_01100	1.116e-08	60.0	COG3462@1|root,COG3462@2|Bacteria,1WKI9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
WZS3_k127_1317877_1	1536772.R70723_07720	4.219e-68	252.0	COG0561@1|root,COG0561@2|Bacteria,1V2N1@1239|Firmicutes,4HAFS@91061|Bacilli,26TJ9@186822|Paenibacillaceae	91061|Bacilli	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_1317877_2	1504823.CCMM01000007_gene471	7.128e-50	197.0	COG0561@1|root,COG0561@2|Bacteria,2NQYP@2323|unclassified Bacteria	2|Bacteria	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	4HBT,Hydrolase_3
WZS3_k127_1317877_4	397287.C807_02497	3.381e-33	131.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,27T8N@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_1323569_3	994573.T472_0218970	4.584e-80	272.0	COG0348@1|root,COG0348@2|Bacteria,1V66G@1239|Firmicutes,25IKG@186801|Clostridia,36IJF@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
WZS3_k127_1323569_1	663278.Ethha_0737	3.508e-109	359.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
WZS3_k127_1323569_4	1209989.TepiRe1_0546	8.219e-67	233.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,42FEX@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
WZS3_k127_1323569_0	1158608.I583_02302	1.102e-160	515.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4H9WR@91061|Bacilli,4AZGS@81852|Enterococcaceae	91061|Bacilli	C	Malic enzyme, N-terminal domain	ytsJ	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
WZS3_k127_1323569_2	1123288.SOV_1c05280	2.279e-80	274.0	COG0441@1|root,COG0441@2|Bacteria,1TPW5@1239|Firmicutes,4H2UI@909932|Negativicutes	909932|Negativicutes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1338687_1	1050201.KB913034_gene1716	8.212e-25	109.0	COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,3VPRJ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	HAD hydrolase, family IA, variant 1	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WZS3_k127_1338687_0	1511.CLOST_0057	1.374e-52	191.0	arCOG05193@1|root,2ZZSG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1338687_2	97138.C820_02113	2.752e-14	74.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,36JUD@31979|Clostridiaceae	186801|Clostridia	M	Acetyltransferase GNAT family	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
WZS3_k127_1377505_2	428127.EUBDOL_00085	3.802e-25	106.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,3VPBC@526524|Erysipelotrichia	526524|Erysipelotrichia	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
WZS3_k127_1377505_1	875454.BAEW01000027_gene1794	1.089e-31	130.0	COG1247@1|root,COG1247@2|Bacteria,1VA2F@1239|Firmicutes,25EX6@186801|Clostridia,22I3T@1570339|Peptoniphilaceae	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_4
WZS3_k127_1377505_0	1122173.AXVL01000020_gene2245	2.052e-174	551.0	COG1486@1|root,COG1486@2|Bacteria,379AE@32066|Fusobacteria	32066|Fusobacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WZS3_k127_1383274_5	658659.HMPREF0983_01828	5.053e-24	102.0	COG3763@1|root,COG3763@2|Bacteria,1VEJC@1239|Firmicutes,3VRKH@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Uncharacterised protein family (UPF0154)	-	-	-	ko:K09976	-	-	-	-	ko00000	-	-	-	UPF0154
WZS3_k127_1383274_3	650150.ERH_0938	8.133e-54	195.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,3VPW7@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WZS3_k127_1383274_0	545696.HOLDEFILI_01657	1.094e-305	947.0	COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,3VP4P@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WZS3_k127_1383274_1	545696.HOLDEFILI_01658	4.778e-296	930.0	COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,3VP07@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WZS3_k127_1383274_7	887929.HMP0721_2200	2.431e-06	57.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,25WYY@186806|Eubacteriaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
WZS3_k127_1383274_6	401526.TcarDRAFT_1565	5.956e-20	97.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4H4KC@909932|Negativicutes	909932|Negativicutes	S	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668	-	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	PGP_phosphatase
WZS3_k127_1383274_2	877415.JNJQ01000001_gene2029	5.437e-55	205.0	COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,3VPXS@526524|Erysipelotrichia	526524|Erysipelotrichia	S	ribosome biogenesis GTPase YqeH	yqeH	-	-	ko:K06948	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
WZS3_k127_1383274_4	545696.HOLDEFILI_03683	9.198e-27	112.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,3VRVA@526524|Erysipelotrichia	526524|Erysipelotrichia	J	RNA-binding protein, YhbY family	-	-	-	-	-	-	-	-	-	-	-	-	CRS1_YhbY
WZS3_k127_1384427_3	1211819.CALK01000004_gene2359	8.769e-96	318.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,3VP3Q@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_1384427_0	1232449.BAHV02000012_gene2211	3.124e-320	1009.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,267RX@186813|unclassified Clostridiales	186801|Clostridia	L	Psort location Cytoplasmic, score	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
WZS3_k127_1384427_1	1211819.CALK01000006_gene2586	1.878e-180	580.0	2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,3VNRQ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1384427_4	545696.HOLDEFILI_03581	6.455e-71	250.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,3VP32@526524|Erysipelotrichia	526524|Erysipelotrichia	S	DHHA1 domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WZS3_k127_1384427_2	1232449.BAHV02000012_gene2209	1.58e-162	519.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,267UV@186813|unclassified Clostridiales	186801|Clostridia	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
WZS3_k127_1397976_3	1499683.CCFF01000014_gene3824	3.454e-62	220.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,24AGQ@186801|Clostridia,36DQG@31979|Clostridiaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	phnE_2	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
WZS3_k127_1397976_2	1408422.JHYF01000004_gene1583	6.126e-77	266.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,24A7G@186801|Clostridia,36FB0@31979|Clostridiaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	phnE_1	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
WZS3_k127_1397976_0	1499683.CCFF01000014_gene3826	2.08e-115	376.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,249GS@186801|Clostridia,36GCJ@31979|Clostridiaceae	186801|Clostridia	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
WZS3_k127_1397976_1	1274374.CBLK010000002_gene3580	6.788e-103	345.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBU5@91061|Bacilli,2758Y@186822|Paenibacillaceae	91061|Bacilli	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
WZS3_k127_1397976_4	411465.PEPMIC_01234	0.0003116	44.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,22I4A@1570339|Peptoniphilaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
WZS3_k127_1405756_1	1232449.BAHV02000010_gene2604	9.246e-54	200.0	COG1307@1|root,COG1307@2|Bacteria,1TXFX@1239|Firmicutes	1239|Firmicutes	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_1405756_0	650150.ERH_0027	2.837e-56	207.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,3VPIU@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_1405756_2	698769.JFBD01000041_gene854	1.246e-25	111.0	COG2365@1|root,COG2365@2|Bacteria,1VA24@1239|Firmicutes,4HMSH@91061|Bacilli	91061|Bacilli	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
WZS3_k127_1416103_0	1232449.BAHV02000012_gene2193	1.937e-49	180.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,24971@186801|Clostridia,267N4@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
WZS3_k127_1416103_1	999413.HMPREF1094_03272	5.761e-48	180.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,3VNQN@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS3_k127_1446996_2	1033810.HLPCO_000056	8.73e-110	361.0	COG0444@1|root,COG0444@2|Bacteria,2NQAA@2323|unclassified Bacteria	2|Bacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS3_k127_1446996_1	702450.CUW_2712	2.38e-129	421.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,3VPCC@526524|Erysipelotrichia	526524|Erysipelotrichia	EP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
WZS3_k127_1446996_3	702450.CUW_2711	1.857e-105	350.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,3VPZ3@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
WZS3_k127_1446996_0	702450.CUW_2710	1.719e-142	470.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,3VPT5@526524|Erysipelotrichia	526524|Erysipelotrichia	E	ABC transporter, substrate-binding protein, family 5	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
WZS3_k127_1446996_4	650150.ERH_0188	5.597e-61	218.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,3VP1V@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
WZS3_k127_1446996_5	1232449.BAHV02000016_gene1848	7.332e-41	158.0	2AHXQ@1|root,318AQ@2|Bacteria,1TUDE@1239|Firmicutes,257GD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1449107_5	1511.CLOST_2510	8.581e-43	163.0	COG1246@1|root,COG1246@2|Bacteria,1UHXM@1239|Firmicutes,24TJG@186801|Clostridia	186801|Clostridia	E	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1449107_4	1211844.CBLM010000110_gene3458	2.524e-55	199.0	COG0693@1|root,COG0693@2|Bacteria,1V0FD@1239|Firmicutes,3VQ1W@526524|Erysipelotrichia	526524|Erysipelotrichia	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
WZS3_k127_1449107_3	706437.HMPREF0813_00558	1.08e-57	206.0	COG0693@1|root,COG0693@2|Bacteria,1V3I7@1239|Firmicutes,4HFNG@91061|Bacilli,42D2P@671232|Streptococcus anginosus group	91061|Bacilli	S	DJ-1/PfpI family	thiJ	-	3.5.1.124	ko:K03152,ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
WZS3_k127_1449107_2	1294142.CINTURNW_2600	2.925e-60	217.0	COG1737@1|root,COG1737@2|Bacteria,1V12C@1239|Firmicutes,25C7E@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6
WZS3_k127_1449107_1	545696.HOLDEFILI_00637	2.687e-238	747.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,3VNW3@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
WZS3_k127_1449107_7	1123263.AUKY01000007_gene2301	1.785e-16	82.0	COG2919@1|root,COG2919@2|Bacteria,1VJ3Q@1239|Firmicutes,3VRW8@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Septum formation initiator	-	-	-	ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
WZS3_k127_1449107_6	1232449.BAHV02000002_gene104	5.439e-20	93.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
WZS3_k127_1449107_0	1211819.CALK01000051_gene1539	2.336e-272	850.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,3VNZW@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WZS3_k127_145824_2	1211819.CALK01000054_gene1107	6.425e-26	109.0	COG0438@1|root,COG0438@2|Bacteria,1V09V@1239|Firmicutes,3VUGU@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
WZS3_k127_145824_1	1415775.U729_1138	6.25e-35	140.0	COG5017@1|root,COG5017@2|Bacteria,1VBCS@1239|Firmicutes,24PN8@186801|Clostridia,36I32@31979|Clostridiaceae	186801|Clostridia	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
WZS3_k127_145824_3	1276246.SCULI_v1c00830	4.313e-15	78.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
WZS3_k127_145824_0	1211819.CALK01000033_gene1386	1.003e-49	183.0	COG4866@1|root,COG4866@2|Bacteria,1TR2J@1239|Firmicutes,3VPNV@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,DUF2156
WZS3_k127_1471473_1	1211819.CALK01000005_gene2472	1.143e-08	59.0	COG0494@1|root,COG0494@2|Bacteria,1VIUK@1239|Firmicutes,3VSB9@526524|Erysipelotrichia	526524|Erysipelotrichia	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
WZS3_k127_1471473_0	999413.HMPREF1094_04469	2.823e-57	211.0	COG0738@1|root,COG0738@2|Bacteria,1V50P@1239|Firmicutes,3VSU2@526524|Erysipelotrichia	526524|Erysipelotrichia	G	LacY proton/sugar symporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1_like
WZS3_k127_1476582_0	1211819.CALK01000052_gene1048	1.064e-55	204.0	COG2746@1|root,COG2746@2|Bacteria,1V2QD@1239|Firmicutes,3VPG8@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Aminoglycoside 3-N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Antibiotic_NAT
WZS3_k127_1476582_3	81824.XP_001750150.1	0.0004084	48.0	COG0526@1|root,KOG0910@2759|Eukaryota,3A8MT@33154|Opisthokonta	33154|Opisthokonta	O	glycerol ether metabolic process	TXN2	GO:0000096,GO:0000098,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009605,GO:0009611,GO:0009628,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0015036,GO:0016054,GO:0016491,GO:0016667,GO:0019752,GO:0030425,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0034284,GO:0036293,GO:0036477,GO:0042221,GO:0042493,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044877,GO:0046395,GO:0048678,GO:0050896,GO:0051716,GO:0055114,GO:0070013,GO:0070482,GO:0071496,GO:0071704,GO:0097447,GO:0097458,GO:0120025,GO:0120038,GO:1901564,GO:1901565,GO:1901575,GO:1901700	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WZS3_k127_1476582_1	1232449.BAHV02000009_gene2417	2.255e-55	198.0	COG1267@1|root,COG1267@2|Bacteria,1V3I0@1239|Firmicutes,24H9D@186801|Clostridia	186801|Clostridia	I	PFAM Phosphatidylglycerophosphatase A	-	-	-	-	-	-	-	-	-	-	-	-	PgpA
WZS3_k127_1476582_2	1123263.AUKY01000026_gene865	1.004e-34	141.0	COG0524@1|root,COG0524@2|Bacteria,1TQR4@1239|Firmicutes,3VQ1J@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Kinase, PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
WZS3_k127_1502357_2	445974.CLORAM_00381	1.405e-45	171.0	COG1737@1|root,COG1737@2|Bacteria,1V00A@1239|Firmicutes,3VSP7@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
WZS3_k127_1502357_0	1499684.CCNP01000018_gene842	4.039e-238	743.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,36EXF@31979|Clostridiaceae	186801|Clostridia	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WZS3_k127_1502357_1	1122173.AXVL01000020_gene2245	1.35e-135	437.0	COG1486@1|root,COG1486@2|Bacteria,379AE@32066|Fusobacteria	32066|Fusobacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WZS3_k127_1504983_4	1123313.ATUT01000001_gene1241	3.539e-12	69.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,3VRA8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WZS3_k127_1504983_0	545696.HOLDEFILI_03739	8.239e-101	334.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,3VPPW@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
WZS3_k127_1504983_2	1211819.CALK01000004_gene2196	1.227e-48	177.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,3VQUV@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
WZS3_k127_1504983_1	1121874.KB892377_gene909	1.872e-49	181.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,3VQZN@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
WZS3_k127_1504983_3	1232449.BAHV02000012_gene2188	1.743e-16	78.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,267TW@186813|unclassified Clostridiales	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
WZS3_k127_154760_5	1121874.KB892377_gene1444	6.625e-159	514.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,3VNY1@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
WZS3_k127_154760_19	545696.HOLDEFILI_03665	1.608e-37	145.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,3VQVS@526524|Erysipelotrichia	526524|Erysipelotrichia	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
WZS3_k127_154760_16	999413.HMPREF1094_03941	2.877e-40	151.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,3VQXJ@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
WZS3_k127_154760_25	1211844.CBLM010000017_gene1455	1.493e-11	72.0	COG1390@1|root,COG1390@2|Bacteria,1V8A3@1239|Firmicutes,3VQU6@526524|Erysipelotrichia	526524|Erysipelotrichia	C	ATP synthase (E/31 kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
WZS3_k127_154760_0	1211844.CBLM010000017_gene1454	6.09e-267	833.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,3VPDV@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
WZS3_k127_154760_3	1211819.CALK01000004_gene2132	4.051e-234	732.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,3VNVV@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WZS3_k127_154760_9	545696.HOLDEFILI_03670	1.138e-73	253.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,3VPBR@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
WZS3_k127_154760_13	768706.Desor_0436	2.917e-49	186.0	COG3327@1|root,COG3327@2|Bacteria,1TRBU@1239|Firmicutes,24UFC@186801|Clostridia,265YB@186807|Peptococcaceae	186801|Clostridia	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
WZS3_k127_154760_6	269797.Mbar_A2155	3.319e-97	328.0	COG3173@1|root,arCOG05239@2157|Archaea	269797.Mbar_A2155|-	S	PFAM Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_154760_10	1124982.MSI_13600	1.512e-66	231.0	2DBP0@1|root,2ZA6P@2|Bacteria,2J7V8@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_154760_26	1504823.CCMM01000013_gene2720	1.383e-06	55.0	2ECW9@1|root,336TH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_154760_1	1121874.KB892377_gene1437	2.302e-251	786.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,3VNU4@526524|Erysipelotrichia	526524|Erysipelotrichia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
WZS3_k127_154760_22	476272.RUMHYD_01320	5.37e-20	93.0	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia,3Y1UU@572511|Blautia	186801|Clostridia	E	Branched-chain amino acid transport protein (AzlD)	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
WZS3_k127_154760_12	767817.Desgi_4269	3.036e-56	204.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,248NN@186801|Clostridia,2640U@186807|Peptococcaceae	186801|Clostridia	E	branched-chain amino acid	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
WZS3_k127_154760_18	264462.Bd0465	1.642e-38	154.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2MT40@213481|Bdellovibrionales,2WJW9@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
WZS3_k127_154760_20	203119.Cthe_2523	4.753e-32	132.0	2CH3Z@1|root,32RP9@2|Bacteria,1V9MP@1239|Firmicutes,24K61@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
WZS3_k127_154760_8	1200792.AKYF01000007_gene840	4.811e-81	279.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
WZS3_k127_154760_15	545696.HOLDEFILI_03728	8.903e-45	168.0	COG1335@1|root,COG1335@2|Bacteria,1TSTB@1239|Firmicutes,3VQK5@526524|Erysipelotrichia	526524|Erysipelotrichia	Q	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
WZS3_k127_154760_7	1274374.CBLK010000003_gene3341	1.364e-93	316.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,26TFZ@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran
WZS3_k127_154760_14	1033810.HLPCO_000208	4.35e-48	183.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	cylB	-	-	ko:K11051	ko02010,map02010	M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
WZS3_k127_154760_11	1410668.JNKC01000005_gene2357	9.153e-60	213.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,36IPV@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
WZS3_k127_154760_24	913865.DOT_4785	1.194e-16	85.0	COG1846@1|root,COG1846@2|Bacteria,1V8EW@1239|Firmicutes,24RW7@186801|Clostridia,265Q5@186807|Peptococcaceae	186801|Clostridia	K	PFAM MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
WZS3_k127_154760_4	1169144.KB910967_gene3408	2.134e-232	740.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli,1ZBEE@1386|Bacillus	91061|Bacilli	V	ABC transporter	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_154760_2	457396.CSBG_01647	2.442e-248	781.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E4P@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_154760_21	931276.Cspa_c16140	3.764e-31	127.0	COG0679@1|root,COG0679@2|Bacteria,1V28G@1239|Firmicutes,24H5F@186801|Clostridia,36WSS@31979|Clostridiaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
WZS3_k127_1569009_1	999413.HMPREF1094_03245	3.017e-91	309.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,3VNPB@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Aminotransferase, class V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS3_k127_1569009_0	1211819.CALK01000009_gene2761	5.383e-145	479.0	COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,3VNPW@526524|Erysipelotrichia	526524|Erysipelotrichia	D	septation ring formation regulator EzrA	ezrA	-	-	ko:K06286	-	-	-	-	ko00000,ko03036	-	-	-	EzrA
WZS3_k127_1592134_0	1321778.HMPREF1982_04095	1.195e-127	416.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes	1239|Firmicutes	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
WZS3_k127_1601179_4	518637.EUBIFOR_02423	5.622e-05	48.0	2CM8T@1|root,32SE0@2|Bacteria,1VBP1@1239|Firmicutes,3VTYS@526524|Erysipelotrichia	526524|Erysipelotrichia	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
WZS3_k127_1601179_0	411902.CLOBOL_05640	3.585e-126	412.0	COG3093@1|root,COG3093@2|Bacteria,1V0AU@1239|Firmicutes,24BH5@186801|Clostridia	186801|Clostridia	K	Addiction module antidote protein, HigA	higA	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
WZS3_k127_1601179_2	1321782.HMPREF1986_00219	3.542e-31	125.0	COG3549@1|root,COG3549@2|Bacteria,1VBF5@1239|Firmicutes,24JP6@186801|Clostridia,2PTHT@265975|Oribacterium	186801|Clostridia	S	Plasmid maintenance system killer	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
WZS3_k127_1601179_1	509191.AEDB02000065_gene605	3.206e-87	293.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia,3WI86@541000|Ruminococcaceae	186801|Clostridia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
WZS3_k127_1601179_3	1280001.BAOA01000058_gene4588	1.718e-08	57.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1XW29@135623|Vibrionales	135623|Vibrionales	V	LD-carboxypeptidase	mccF	GO:0008150,GO:0008152,GO:0009404,GO:0009987,GO:0019748,GO:0030153,GO:0044237	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
WZS3_k127_1622564_1	1382305.AZUC01000048_gene1672	1.648e-19	89.0	COG2021@1|root,COG2021@2|Bacteria,1V0J9@1239|Firmicutes,4HCZZ@91061|Bacilli	91061|Bacilli	E	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	estA3	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS3_k127_1622564_0	1087481.AGFX01000041_gene847	5.433e-105	348.0	COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli,26SF1@186822|Paenibacillaceae	91061|Bacilli	GK	fructokinase	gmuE	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
WZS3_k127_1622564_2	649639.Bcell_3106	0.0004509	46.0	COG3156@1|root,COG3156@2|Bacteria,1UYI3@1239|Firmicutes,4HDN1@91061|Bacilli,1ZGI5@1386|Bacillus	91061|Bacilli	U	PilX N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
WZS3_k127_163314_3	476272.RUMHYD_00385	3.784e-20	95.0	COG1905@1|root,COG1905@2|Bacteria,1VAK1@1239|Firmicutes,25CD1@186801|Clostridia	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
WZS3_k127_163314_2	518637.EUBIFOR_00313	1.188e-34	136.0	2D5KY@1|root,32TJC@2|Bacteria,1VD7P@1239|Firmicutes,3VRYY@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_163314_0	994573.T472_0208585	1.603e-65	231.0	COG0491@1|root,COG0491@2|Bacteria,1TSU6@1239|Firmicutes,24DDT@186801|Clostridia,36FFX@31979|Clostridiaceae	186801|Clostridia	S	metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS3_k127_163314_1	86416.Clopa_2106	1.34e-39	152.0	COG1846@1|root,COG1846@2|Bacteria,1V71W@1239|Firmicutes,25CVF@186801|Clostridia	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_163314_4	416591.Tlet_1035	2.007e-07	55.0	COG3976@1|root,COG3976@2|Bacteria,2GDNU@200918|Thermotogae	200918|Thermotogae	S	PFAM FMN-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
WZS3_k127_163371_0	1211819.CALK01000009_gene2768	7.417e-275	860.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,3VPK4@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WZS3_k127_1641679_2	658086.HMPREF0994_00566	5.137e-85	299.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,2498Q@186801|Clostridia,27JUX@186928|unclassified Lachnospiraceae	186801|Clostridia	NU	Secretory protein of YscJ/FliF family	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
WZS3_k127_1641679_1	457421.CBFG_02713	2.04e-113	374.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia,267T2@186813|unclassified Clostridiales	186801|Clostridia	N	FliG C-terminal domain	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
WZS3_k127_1641679_0	742733.HMPREF9469_03848	4.667e-128	415.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,21Y0I@1506553|Lachnoclostridium	186801|Clostridia	NU	ATPase FliI YscN family	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WZS3_k127_167351_7	1121874.KB892380_gene1696	7.148e-29	132.0	COG3559@1|root,COG3559@2|Bacteria	2|Bacteria	M	Exporter of polyketide antibiotics	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WZS3_k127_167351_3	1121874.KB892380_gene1695	2.39e-86	296.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,3VQ5J@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_167351_6	1232449.BAHV02000002_gene80	9.996e-34	138.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,268YN@186813|unclassified Clostridiales	186801|Clostridia	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_167351_8	189426.PODO_04560	9.907e-23	104.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,26Z1F@186822|Paenibacillaceae	91061|Bacilli	K	GntR family transcriptional regulator	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
WZS3_k127_167351_4	1321786.HMPREF1992_01700	2.332e-51	186.0	COG1670@1|root,COG1670@2|Bacteria,1UM04@1239|Firmicutes,4H8WJ@909932|Negativicutes	909932|Negativicutes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_167351_1	997884.HMPREF1068_04141	6.712e-134	438.0	COG1373@1|root,COG1373@2|Bacteria,4NG8U@976|Bacteroidetes,2FP3K@200643|Bacteroidia,4APDZ@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WZS3_k127_167351_2	1294142.CINTURNW_3872	2.527e-89	302.0	COG1814@1|root,COG1814@2|Bacteria,1UZVX@1239|Firmicutes,24BSJ@186801|Clostridia,36FHG@31979|Clostridiaceae	186801|Clostridia	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
WZS3_k127_167351_0	428127.EUBDOL_02080	2.816e-236	745.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,3VNSD@526524|Erysipelotrichia	526524|Erysipelotrichia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
WZS3_k127_167351_5	1123263.AUKY01000005_gene2339	7.963e-40	156.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,3VP1P@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	gidB	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
WZS3_k127_169341_0	445974.CLORAM_00381	3.288e-64	229.0	COG1737@1|root,COG1737@2|Bacteria,1V00A@1239|Firmicutes,3VSP7@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
WZS3_k127_169341_3	360106.CFF8240_0360	3.052e-18	91.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,42MSG@68525|delta/epsilon subdivisions,2YMX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ATP-binding protein	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
WZS3_k127_169341_2	879308.HMPREF9130_0973	8.875e-54	196.0	COG4662@1|root,COG4662@2|Bacteria,1TRK7@1239|Firmicutes,249VG@186801|Clostridia,22IGZ@1570339|Peptoniphilaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
WZS3_k127_169341_1	1123009.AUID01000028_gene340	3.006e-58	206.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,26968@186813|unclassified Clostridiales	186801|Clostridia	H	Probable molybdopterin binding domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
WZS3_k127_169341_4	938293.CAJU020000015_gene1875	6.179e-05	45.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,24HBA@186801|Clostridia,22HKE@1570339|Peptoniphilaceae	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
WZS3_k127_172302_0	771875.Ferpe_0668	2.536e-283	890.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,2GCD4@200918|Thermotogae	200918|Thermotogae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_172302_1	562981.HMPREF0428_00610	1.019e-50	182.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HFYU@91061|Bacilli,3WG3G@539002|Bacillales incertae sedis	91061|Bacilli	K	Helix-turn-helix domain	cadC5	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS3_k127_172302_3	883069.HMPREF9238_01270	8.905e-16	78.0	COG2026@1|root,COG2026@2|Bacteria,2IS0Z@201174|Actinobacteria,4D861@85005|Actinomycetales	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
WZS3_k127_172302_4	864565.HMPREF0379_0355	4.167e-05	49.0	2EI1I@1|root,330GC@2|Bacteria,1VF93@1239|Firmicutes,24SDR@186801|Clostridia,25U53@186804|Peptostreptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
WZS3_k127_172302_2	1499968.TCA2_1861	3.083e-22	100.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,4HAUM@91061|Bacilli,26RSH@186822|Paenibacillaceae	91061|Bacilli	G	Major facilitator superfamily	-	-	-	ko:K08174	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
WZS3_k127_1723357_1	650150.ERH_1670	1.834e-54	197.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,3VPBK@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	trmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WZS3_k127_1723357_0	1305836.AXVE01000014_gene1210	1.955e-71	250.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli,26E0K@186818|Planococcaceae	91061|Bacilli	L	TatD related DNase	tatD	GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
WZS3_k127_1723357_2	1033734.CAET01000001_gene3959	3.17e-36	141.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,1ZD7C@1386|Bacillus	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
WZS3_k127_1724389_1	1410668.JNKC01000004_gene53	4.278e-164	526.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,36DTA@31979|Clostridiaceae	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WZS3_k127_1724389_0	1321778.HMPREF1982_04393	7.716e-195	616.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,267QN@186813|unclassified Clostridiales	186801|Clostridia	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
WZS3_k127_1724389_2	1321778.HMPREF1982_04392	1.02e-49	181.0	COG2021@1|root,COG2021@2|Bacteria,1UN4B@1239|Firmicutes	1239|Firmicutes	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
WZS3_k127_176251_0	545696.HOLDEFILI_01902	2.726e-244	761.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,3VP04@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WZS3_k127_176251_1	1211819.CALK01000009_gene2750	2.004e-20	93.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,3VR5G@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
WZS3_k127_1772406_0	1286171.EAL2_c12720	6.418e-228	719.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,25UU8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WZS3_k127_1772406_1	655812.HMPREF0061_1495	2.442e-127	415.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4ISFB@91061|Bacilli,27ET0@186827|Aerococcaceae	91061|Bacilli	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.41,1.1.1.42,1.1.1.85	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00432,M00535,M00740	R00267,R00268,R00709,R00994,R01899,R04426,R10052	RC00001,RC00084,RC00114,RC00417,RC00626,RC02801,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
WZS3_k127_1772406_2	994573.T472_0218945	1.923e-69	240.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,36DHF@31979|Clostridiaceae	186801|Clostridia	C	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WZS3_k127_1782377_2	511051.CSE_02100	5.467e-75	261.0	COG3426@1|root,COG3426@2|Bacteria	2|Bacteria	C	butyrate kinase activity	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase,PTA_PTB
WZS3_k127_1782377_1	350688.Clos_2414	1.597e-84	289.0	COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia,36DC6@31979|Clostridiaceae	186801|Clostridia	C	phosphate butyryltransferase	ptb	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747,GO:0050182	2.3.1.19	ko:K00634	ko00650,ko01100,map00650,map01100	-	R01174	RC00004,RC02816	ko00000,ko00001,ko01000	-	-	-	PTA_PTB
WZS3_k127_1782377_3	665952.HMPREF1015_02660	6.314e-64	229.0	COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli,1ZAQI@1386|Bacillus	91061|Bacilli	S	glyoxalase	catE	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
WZS3_k127_1782377_6	1139996.OMQ_01529	5.23e-14	77.0	COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UMQE@1239|Firmicutes,4IUVX@91061|Bacilli,4B610@81852|Enterococcaceae	91061|Bacilli	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
WZS3_k127_1782377_5	1139996.OMQ_01529	3.517e-14	76.0	COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UMQE@1239|Firmicutes,4IUVX@91061|Bacilli,4B610@81852|Enterococcaceae	91061|Bacilli	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
WZS3_k127_1782377_4	518637.EUBIFOR_02221	4.304e-47	175.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,3VPP0@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Necessary for normal cell division and for the maintenance of normal septation	ysxC	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
WZS3_k127_1782377_0	1123263.AUKY01000010_gene1851	2.514e-221	692.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,3VPIW@526524|Erysipelotrichia	526524|Erysipelotrichia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS3_k127_1798976_1	86416.Clopa_0749	5.164e-122	402.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,36EK3@31979|Clostridiaceae	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
WZS3_k127_1798976_2	1286171.EAL2_c07940	1.266e-43	163.0	COG5609@1|root,COG5609@2|Bacteria,1V6YC@1239|Firmicutes,24QTG@186801|Clostridia	186801|Clostridia	S	Uncharacterized conserved protein (DUF2294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2294
WZS3_k127_1798976_0	994573.T472_0210925	2.221e-212	672.0	COG1892@1|root,COG1892@2|Bacteria,1V0S3@1239|Firmicutes,24B8U@186801|Clostridia,36G04@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppcA	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase_2
WZS3_k127_1798976_3	1321814.HMPREF9089_00032	1.159e-32	128.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,25UU8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
WZS3_k127_1804593_2	1235793.C809_01179	6.073e-40	156.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,27M5Z@186928|unclassified Lachnospiraceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
WZS3_k127_1804593_0	411471.SUBVAR_04799	1.481e-93	321.0	COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,24BMN@186801|Clostridia,3WJP1@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
WZS3_k127_1804593_1	525919.Apre_1582	4.213e-41	158.0	COG0657@1|root,COG0657@2|Bacteria,1V95Z@1239|Firmicutes,25KMZ@186801|Clostridia,22IIZ@1570339|Peptoniphilaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WZS3_k127_1822353_0	1499683.CCFF01000017_gene1523	1.469e-86	301.0	COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,24EV5@186801|Clostridia,36EX5@31979|Clostridiaceae	186801|Clostridia	F	5'-nucleotidase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,Metallophos
WZS3_k127_1822353_1	572544.Ilyop_1566	1.641e-47	172.0	COG1592@1|root,COG1592@2|Bacteria,37A01@32066|Fusobacteria	32066|Fusobacteria	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WZS3_k127_1823006_3	1410674.JNKU01000008_gene1258	4.486e-09	61.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli,3F4CD@33958|Lactobacillaceae	91061|Bacilli	E	Aminotransferase class V	iscS2	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS3_k127_1823006_4	512564.MCRO_0743	3.059e-06	53.0	COG3118@1|root,COG3118@2|Bacteria,3WTYZ@544448|Tenericutes	544448|Tenericutes	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WZS3_k127_1823006_0	880072.Desac_0814	3.894e-68	246.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,43DC6@68525|delta/epsilon subdivisions,2X8I6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1823006_1	1384056.N787_04495	3.786e-35	138.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1X701@135614|Xanthomonadales	135614|Xanthomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
WZS3_k127_1823006_2	1449050.JNLE01000003_gene1580	3.637e-30	123.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,36EER@31979|Clostridiaceae	186801|Clostridia	S	membrane transporter protein	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WZS3_k127_1841132_3	1410668.JNKC01000001_gene1985	1.709e-20	92.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Peripla_BP_3
WZS3_k127_1841132_2	610130.Closa_2821	1.19e-84	293.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia,21YT1@1506553|Lachnoclostridium	186801|Clostridia	S	AI-2E family transporter	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS3_k127_1841132_0	335541.Swol_0984	2.69e-132	433.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WZS3_k127_1841132_1	1123009.AUID01000014_gene1788	4.966e-123	399.0	COG1013@1|root,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,25CAJ@186801|Clostridia,26ACG@186813|unclassified Clostridiales	186801|Clostridia	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
WZS3_k127_1850874_1	1120746.CCNL01000017_gene2425	2.668e-75	258.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
WZS3_k127_1850874_2	1120746.CCNL01000017_gene2424	1.861e-18	89.0	2E455@1|root,32Z17@2|Bacteria	2|Bacteria	S	Late competence development protein ComFB	-	-	-	ko:K02241	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	ComFB
WZS3_k127_1850874_4	877411.JMMA01000002_gene2443	6.575e-11	68.0	2A5J1@1|root,30U9B@2|Bacteria,1US74@1239|Firmicutes,25A60@186801|Clostridia,3WR82@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1850874_0	457421.CBFG_02682	2.556e-93	323.0	COG1256@1|root,COG1256@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia,2695X@186813|unclassified Clostridiales	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WZS3_k127_1850874_5	397278.JOJN01000001_gene2881	1.457e-06	59.0	COG1344@1|root,COG1344@2|Bacteria,2IA40@201174|Actinobacteria,4DNBS@85009|Propionibacteriales	201174|Actinobacteria	N	Bacterial flagellin C-terminal helical region	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WZS3_k127_1857889_2	1499683.CCFF01000016_gene902	4.727e-43	167.0	COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,24M7G@186801|Clostridia,36H0F@31979|Clostridiaceae	186801|Clostridia	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,GNAT_acetyltran
WZS3_k127_1857889_0	545696.HOLDEFILI_01767	1.003e-164	524.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,3VNTG@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
WZS3_k127_1857889_1	1211819.CALK01000009_gene2839	1.235e-48	183.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,3VNTD@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WZS3_k127_1858808_2	1408422.JHYF01000008_gene3573	9.727e-34	138.0	arCOG05203@1|root,32RHJ@2|Bacteria,1VBFD@1239|Firmicutes,24Q1N@186801|Clostridia,36JY2@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1858808_0	1211819.CALK01000015_gene1219	3.231e-134	437.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,3VPMY@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS3_k127_1858808_3	1151292.QEW_1243	1.148e-28	119.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,25TR5@186804|Peptostreptococcaceae	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WZS3_k127_1858808_1	768710.DesyoDRAFT_3676	6.39e-83	282.0	COG2021@1|root,COG2021@2|Bacteria,1V0J9@1239|Firmicutes,25BWV@186801|Clostridia	186801|Clostridia	E	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
WZS3_k127_1863270_0	1410668.JNKC01000005_gene2194	3.063e-60	225.0	COG3307@1|root,COG3307@2|Bacteria,1V6KK@1239|Firmicutes,25BNJ@186801|Clostridia,36WKX@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WZS3_k127_1863270_1	1410668.JNKC01000005_gene2194	4.226e-36	146.0	COG3307@1|root,COG3307@2|Bacteria,1V6KK@1239|Firmicutes,25BNJ@186801|Clostridia,36WKX@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WZS3_k127_1871426_0	658086.HMPREF0994_00042	6.242e-96	323.0	COG2253@1|root,COG2253@2|Bacteria,1TS2W@1239|Firmicutes,24EV3@186801|Clostridia,27K0W@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WZS3_k127_1871426_1	592015.HMPREF1705_00516	2.19e-69	244.0	COG5340@1|root,COG5340@2|Bacteria,3TC8S@508458|Synergistetes	508458|Synergistetes	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1
WZS3_k127_1871426_2	158190.SpiGrapes_0772	3.802e-34	138.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4,Fer4_10,Fer4_5,Fer4_9
WZS3_k127_1906429_5	552396.HMPREF0863_02814	1.014e-75	258.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,3VNPU@526524|Erysipelotrichia	526524|Erysipelotrichia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K16786	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
WZS3_k127_1906429_11	552396.HMPREF0863_02807	9.808e-37	147.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,3VQY7@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
WZS3_k127_1906429_8	545696.HOLDEFILI_01388	2.373e-57	201.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,3VQM7@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
WZS3_k127_1906429_1	545696.HOLDEFILI_01387	1.361e-152	487.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,3VPDD@526524|Erysipelotrichia	526524|Erysipelotrichia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
WZS3_k127_1906429_7	1121874.KB892378_gene462	9.456e-64	220.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,3VQG6@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
WZS3_k127_1906429_9	552396.HMPREF0863_02802	2.88e-56	198.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,3VQQU@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
WZS3_k127_1906429_13	908340.HMPREF9406_2514	1.144e-16	79.0	COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,24UGF@186801|Clostridia,36P0F@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
WZS3_k127_1906429_12	428127.EUBDOL_00544	3.585e-35	134.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,3VR4F@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
WZS3_k127_1906429_2	545696.HOLDEFILI_01383	4.335e-111	364.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,3VPT3@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
WZS3_k127_1906429_4	1211819.CALK01000047_gene1840	6.624e-81	274.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,3VQ10@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
WZS3_k127_1906429_0	1211819.CALK01000047_gene1839	8.761e-197	621.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,3VPJG@526524|Erysipelotrichia	526524|Erysipelotrichia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
WZS3_k127_1906429_6	1211819.CALK01000047_gene1838	4.46e-67	231.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,3VQMC@526524|Erysipelotrichia	526524|Erysipelotrichia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
WZS3_k127_1906429_3	552396.HMPREF0863_02795	5.512e-84	280.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,3VQ7N@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
WZS3_k127_1906429_10	545696.HOLDEFILI_01378	1.107e-50	182.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,3VQGV@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
WZS3_k127_1955430_3	1211844.CBLM010000051_gene519	2.667e-34	132.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,3VPH4@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WZS3_k127_1955430_2	1232449.BAHV02000001_gene431	6.122e-56	203.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
WZS3_k127_1955430_4	650150.ERH_1089	2.519e-33	136.0	COG1670@1|root,COG1670@2|Bacteria,1V2FI@1239|Firmicutes,3VRKK@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_1955430_0	545696.HOLDEFILI_02006	0.0	1185.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,3VP6V@526524|Erysipelotrichia	526524|Erysipelotrichia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
WZS3_k127_1955430_1	545696.HOLDEFILI_02012	5.409e-117	380.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,3VNZB@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WZS3_k127_1967748_4	665571.STHERM_c12880	0.0002543	44.0	COG2003@1|root,COG2003@2|Bacteria,2J7P5@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WZS3_k127_1967748_2	1211819.CALK01000009_gene2798	9.425e-63	226.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,3VPN7@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WZS3_k127_1967748_3	552396.HMPREF0863_01171	1.774e-24	109.0	2CE12@1|root,33KXB@2|Bacteria,1VKFT@1239|Firmicutes,3VS3H@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_1967748_1	908340.HMPREF9406_0518	9.445e-85	291.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes	1239|Firmicutes	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
WZS3_k127_1967748_0	545696.HOLDEFILI_01836	4.082e-138	455.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,3VNWN@526524|Erysipelotrichia	526524|Erysipelotrichia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
WZS3_k127_197554_2	545696.HOLDEFILI_01271	1.301e-06	50.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,3VP96@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Cell cycle protein, FtsW RodA SpoVE family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
WZS3_k127_197554_0	1121874.KB892380_gene1733	2.261e-69	244.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,3VP02@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WZS3_k127_197554_1	1229517.AMFD01000009_gene825	7.197e-18	91.0	COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli,1YBMP@1357|Lactococcus	91061|Bacilli	S	CYTH	yjbK	-	-	-	-	-	-	-	-	-	-	-	CYTH
WZS3_k127_2011190_5	1487921.DP68_15520	1.697e-10	65.0	COG0664@1|root,COG0664@2|Bacteria,1V5MZ@1239|Firmicutes,24AQS@186801|Clostridia,36G37@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, Crp Fnr family(	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WZS3_k127_2011190_4	386415.NT01CX_0892	7.672e-20	94.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,36K5Z@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
WZS3_k127_2011190_2	1211819.CALK01000017_gene473	3.965e-40	156.0	COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,3VQZM@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS3_k127_2011190_3	1121289.JHVL01000017_gene766	5.669e-28	117.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,36KRW@31979|Clostridiaceae	186801|Clostridia	S	protein with conserved CXXC pairs	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
WZS3_k127_2011190_0	877415.JNJQ01000002_gene2334	5.378e-131	430.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,3VPMI@526524|Erysipelotrichia	526524|Erysipelotrichia	C	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
WZS3_k127_2011190_1	877415.JNJQ01000002_gene2333	2.611e-43	164.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,3VPRF@526524|Erysipelotrichia	526524|Erysipelotrichia	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Fer2_BFD
WZS3_k127_2022278_5	545696.HOLDEFILI_03727	6.017e-182	578.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,3VP2X@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
WZS3_k127_2022278_6	1211844.CBLM010000097_gene2395	2.775e-118	388.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,3VP69@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS3_k127_2022278_8	650150.ERH_1003	2.462e-104	349.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,3VPKK@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS3_k127_2022278_2	1469948.JPNB01000001_gene1870	8.201e-234	732.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,36UI0@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	yufO	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WZS3_k127_2022278_7	1123009.AUID01000032_gene1322	2.133e-106	355.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,267P3@186813|unclassified Clostridiales	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	tmpC	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WZS3_k127_2022278_3	545696.HOLDEFILI_03713	6.532e-229	728.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,3VPPT@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Belongs to the FtsK SpoIIIE SftA family	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
WZS3_k127_2022278_0	1211819.CALK01000004_gene2169	3.367e-237	745.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,3VP2V@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
WZS3_k127_2022278_4	658659.HMPREF0983_01213	3.231e-204	645.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,3VPEZ@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,TRAM,UPF0004
WZS3_k127_2022278_11	428127.EUBDOL_01273	5.053e-24	102.0	COG2221@1|root,COG2221@2|Bacteria,1UKD1@1239|Firmicutes,3VRT4@526524|Erysipelotrichia	526524|Erysipelotrichia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
WZS3_k127_2022278_10	1232449.BAHV02000010_gene3190	1.325e-79	273.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,267QK@186813|unclassified Clostridiales	186801|Clostridia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
WZS3_k127_2022278_1	545696.HOLDEFILI_03706	1.146e-234	736.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,3VNR1@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
WZS3_k127_2022278_9	908340.HMPREF9406_1533	1.131e-80	271.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,36DUE@31979|Clostridiaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WZS3_k127_205141_1	706433.HMPREF9430_00777	3.865e-42	159.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,3VQH6@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
WZS3_k127_205141_0	658659.HMPREF0983_01182	1.617e-90	305.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,3VNQX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
WZS3_k127_2086208_0	1232449.BAHV02000010_gene2853	3.974e-233	730.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,267XD@186813|unclassified Clostridiales	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WZS3_k127_2086208_6	545696.HOLDEFILI_03677	5.435e-34	137.0	COG3599@1|root,COG3599@2|Bacteria,1VFQA@1239|Firmicutes,3VRM4@526524|Erysipelotrichia	526524|Erysipelotrichia	D	DivIVA protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
WZS3_k127_2086208_5	1211819.CALK01000004_gene2138	2.023e-50	182.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,3VQMG@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
WZS3_k127_2086208_4	428127.EUBDOL_01970	2.488e-62	220.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,3VQIE@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
WZS3_k127_2086208_1	1211819.CALK01000014_gene453	6.488e-94	317.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,3VPED@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
WZS3_k127_2086208_3	650150.ERH_1072	7.591e-75	262.0	COG0770@1|root,COG0770@2|Bacteria,1TS8M@1239|Firmicutes,3VQB6@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
WZS3_k127_2086208_2	877415.JNJQ01000002_gene2355	7.959e-91	316.0	COG1075@1|root,COG1075@2|Bacteria,1UYGR@1239|Firmicutes,3VNWH@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
WZS3_k127_2093654_2	573413.Spirs_0612	9.48e-06	50.0	COG1014@1|root,COG1014@2|Bacteria,2J8M0@203691|Spirochaetes	203691|Spirochaetes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
WZS3_k127_2093654_0	1443125.Z962_11115	7.282e-219	714.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,36F39@31979|Clostridiaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG2	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
WZS3_k127_2093654_1	1443125.Z962_11120	5.117e-36	153.0	COG0845@1|root,COG0845@2|Bacteria,1V3TH@1239|Firmicutes,24AAF@186801|Clostridia,36FC9@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WZS3_k127_2112128_0	1123288.SOV_6c01820	1.234e-85	293.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,4H3WF@909932|Negativicutes	909932|Negativicutes	T	PFAM metal-dependent phosphohydrolase HD sub	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS3_k127_2112128_3	754331.AEME01000001_gene905	5.159e-05	46.0	2DRC0@1|root,33B61@2|Bacteria,1NHS4@1224|Proteobacteria,1SGUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2112128_2	221027.JO40_09540	8.876e-30	126.0	COG3619@1|root,COG3619@2|Bacteria,2J81A@203691|Spirochaetes	203691|Spirochaetes	S	Protein of unknown function (DUF1275)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
WZS3_k127_2112128_1	941824.TCEL_00650	8.808e-69	240.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,36HS7@31979|Clostridiaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
WZS3_k127_2113826_1	1321778.HMPREF1982_04392	1.385e-71	248.0	COG2021@1|root,COG2021@2|Bacteria,1UN4B@1239|Firmicutes	1239|Firmicutes	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
WZS3_k127_2113826_0	1541959.KQ51_01057	9.967e-83	277.0	COG0427@1|root,COG0427@2|Bacteria,3WT7D@544448|Tenericutes	544448|Tenericutes	C	Acetyl-CoA hydrolase/transferase N-terminal domain	ach1	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
WZS3_k127_2131654_3	545696.HOLDEFILI_03866	2.121e-71	250.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,3VPKC@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
WZS3_k127_2131654_1	1121874.KB892379_gene88	7.008e-92	308.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,3VQBE@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WZS3_k127_2131654_6	1121874.KB892377_gene1163	1.161e-36	143.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,3VRFT@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WZS3_k127_2131654_5	717606.PaecuDRAFT_4188	3.566e-42	158.0	COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,4HKQR@91061|Bacilli,26XSN@186822|Paenibacillaceae	91061|Bacilli	K	MarR family transcriptional regulator	sarZ	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_2131654_2	588581.Cpap_2192	9.259e-76	258.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,3WH4S@541000|Ruminococcaceae	186801|Clostridia	O	Glutathione peroxidase	gpxA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WZS3_k127_2131654_7	471875.RUMLAC_02741	6.615e-17	83.0	COG0317@1|root,COG0317@2|Bacteria,1VC5K@1239|Firmicutes,24NB3@186801|Clostridia,3WK1V@541000|Ruminococcaceae	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
WZS3_k127_2131654_8	889204.HMPREF9423_0381	1.01e-10	65.0	COG0317@1|root,COG0317@2|Bacteria,1VC5K@1239|Firmicutes	1239|Firmicutes	KT	COG0317 Guanosine polyphosphate pyrophosphohydrolases synthetases	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
WZS3_k127_2131654_0	1211844.CBLM010000041_gene2756	3.101e-126	408.0	COG2220@1|root,COG2220@2|Bacteria,1TRXD@1239|Firmicutes,3VPSX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WZS3_k127_2131654_9	1514668.JOOA01000002_gene3470	0.0004295	47.0	COG2161@1|root,COG2161@2|Bacteria,1VFNS@1239|Firmicutes,24R8R@186801|Clostridia,3WKPE@541000|Ruminococcaceae	186801|Clostridia	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
WZS3_k127_2131654_4	622312.ROSEINA2194_00212	2.666e-46	172.0	COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,25B3M@186801|Clostridia	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
WZS3_k127_2161864_2	373903.Hore_06020	1.205e-05	55.0	COG3156@1|root,COG3156@2|Bacteria,1U7T3@1239|Firmicutes,24SSX@186801|Clostridia,3WBZY@53433|Halanaerobiales	186801|Clostridia	U	type II secretion system protein K	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2161864_0	931626.Awo_c02030	1.388e-80	282.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,25WG2@186806|Eubacteriaceae	186801|Clostridia	U	Type II secretory pathway, component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WZS3_k127_2161864_1	1232449.BAHV02000018_gene1690	1.228e-14	82.0	COG4972@1|root,COG4972@2|Bacteria	2|Bacteria	NU	Pilus assembly protein	hofM	GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K02461,ko:K02662,ko:K02663,ko:K12288	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	PilM_2,PilN
WZS3_k127_2171833_22	706433.HMPREF9430_01544	7.43e-07	59.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,3VQC4@526524|Erysipelotrichia	526524|Erysipelotrichia	GKT	Mga helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
WZS3_k127_2171833_6	1461580.CCAS010000003_gene461	1.237e-116	382.0	COG1023@1|root,COG1023@2|Bacteria,1UHN4@1239|Firmicutes,4IS44@91061|Bacilli,1ZS1B@1386|Bacillus	91061|Bacilli	G	6-phosphogluconate dehydrogenase	yqeC	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WZS3_k127_2171833_9	994573.T472_0209470	4.444e-98	326.0	COG3715@1|root,COG3715@2|Bacteria,1TSKN@1239|Firmicutes,24B5I@186801|Clostridia,36GXA@31979|Clostridiaceae	186801|Clostridia	G	PTS system sorbose-specific iic component	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
WZS3_k127_2171833_5	994573.T472_0209475	1.914e-117	383.0	COG3716@1|root,COG3716@2|Bacteria,1UXZH@1239|Firmicutes,247IY@186801|Clostridia,36GVV@31979|Clostridiaceae	186801|Clostridia	G	PTS system mannose fructose sorbose family	-	-	-	ko:K02796,ko:K17467	ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060	M00276,M00610	R02630,R10407	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1,4.A.6.1.17	-	-	EII-Sor,EIID-AGA
WZS3_k127_2171833_13	697303.Thewi_1906	5.511e-53	191.0	COG3444@1|root,COG3444@2|Bacteria,1V7VF@1239|Firmicutes,24KII@186801|Clostridia,42GS7@68295|Thermoanaerobacterales	186801|Clostridia	G	system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
WZS3_k127_2171833_7	688269.Theth_1754	6.588e-113	373.0	COG1052@1|root,COG1052@2|Bacteria,2GCMG@200918|Thermotogae	200918|Thermotogae	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS3_k127_2171833_19	1415774.U728_2281	5.474e-28	118.0	COG2893@1|root,COG2893@2|Bacteria,1VB4C@1239|Firmicutes,24MTQ@186801|Clostridia,36VVB@31979|Clostridiaceae	186801|Clostridia	G	PTS system mannose fructose sorbose family	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
WZS3_k127_2171833_8	748727.CLJU_c11620	7.958e-102	340.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,36HUN@31979|Clostridiaceae	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS05700	2-Hacid_dh,2-Hacid_dh_C
WZS3_k127_2171833_10	1410653.JHVC01000013_gene3649	1.41e-85	287.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia,36ETT@31979|Clostridiaceae	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
WZS3_k127_2171833_18	1408438.JADD01000010_gene1852	1.985e-28	123.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,4HJS5@91061|Bacilli,27F18@186827|Aerococcaceae	91061|Bacilli	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WZS3_k127_2171833_11	935837.JAEK01000053_gene1443	2.485e-73	265.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,4H9W6@91061|Bacilli,1ZD0J@1386|Bacillus	91061|Bacilli	G	Belongs to the FGGY kinase family	gntK	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
WZS3_k127_2171833_21	1384484.AEQU_0168	6.545e-09	67.0	COG1396@1|root,COG1396@2|Bacteria,2I6JU@201174|Actinobacteria,4CWK5@84998|Coriobacteriia	84998|Coriobacteriia	K	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
WZS3_k127_2171833_15	1294142.CINTURNW_3996	1.131e-46	176.0	2AKUT@1|root,31BMY@2|Bacteria,1V967@1239|Firmicutes,24DHX@186801|Clostridia,36HU3@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2171833_16	1262449.CP6013_3330	1.598e-46	169.0	COG1695@1|root,COG1695@2|Bacteria,1VA94@1239|Firmicutes,24N33@186801|Clostridia,36JKC@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
WZS3_k127_2171833_3	1541960.KQ78_01154	5.712e-132	428.0	COG1609@1|root,COG1609@2|Bacteria,3WT51@544448|Tenericutes	544448|Tenericutes	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
WZS3_k127_2171833_2	1541960.KQ78_01151	2.876e-139	452.0	COG1175@1|root,COG1175@2|Bacteria,3WTKR@544448|Tenericutes	544448|Tenericutes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
WZS3_k127_2171833_4	1541959.KQ51_01497	8.773e-122	396.0	COG0395@1|root,COG0395@2|Bacteria,3WTKW@544448|Tenericutes	544448|Tenericutes	P	Binding-protein-dependent transport system inner membrane component	araQ_2	-	-	ko:K10119,ko:K10202	ko02010,map02010	M00196,M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18,3.A.1.1.28	-	-	BPD_transp_1
WZS3_k127_2171833_14	1541960.KQ78_01149	7.657e-52	193.0	COG0637@1|root,COG0637@2|Bacteria,3WTE2@544448|Tenericutes	544448|Tenericutes	S	beta-phosphoglucomutase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
WZS3_k127_2171833_1	1541960.KQ78_01148	6.12e-184	600.0	COG1554@1|root,COG1554@2|Bacteria,3WT2U@544448|Tenericutes	544448|Tenericutes	G	Glycosyl hydrolase family 65 central catalytic domain	treP	-	2.4.1.64,2.4.1.8	ko:K00691,ko:K04844,ko:K05342	ko00500,ko01100,map00500,map01100	-	R01555,R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
WZS3_k127_2171833_0	1541959.KQ51_01495	2.185e-188	596.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
WZS3_k127_2171833_12	994573.T472_0218000	9.777e-57	208.0	COG4231@1|root,COG4231@2|Bacteria	2|Bacteria	C	indolepyruvate ferredoxin oxidoreductase activity	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,Pyr_redox_2
WZS3_k127_2171833_20	877415.JNJQ01000023_gene2520	1.416e-16	85.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes	1239|Firmicutes	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WZS3_k127_2171833_17	545696.HOLDEFILI_00300	4.565e-38	149.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,3VP30@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WZS3_k127_2184153_0	1408424.JHYI01000006_gene481	5.377e-83	290.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,1ZPV2@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 3 family	bglB	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
WZS3_k127_2184153_1	657322.FPR_25530	3.56e-26	110.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3WHQA@541000|Ruminococcaceae	186801|Clostridia	H	Carbohydrate kinase, FGGY family protein	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
WZS3_k127_2206235_1	1120746.CCNL01000011_gene1534	6.689e-18	87.0	COG1921@1|root,COG1921@2|Bacteria	2|Bacteria	E	L-seryl-tRNASec selenium transferase activity	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
WZS3_k127_2206235_0	1499684.CCNP01000025_gene3605	1.143e-84	286.0	2DBAP@1|root,2Z844@2|Bacteria,1TQX7@1239|Firmicutes,24BJK@186801|Clostridia,36R85@31979|Clostridiaceae	186801|Clostridia	S	Pfam:DUF1341	-	-	4.1.2.14	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	M00061,M00631	R05605	RC00307,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	KDGP_aldolase
WZS3_k127_2206235_2	326423.RBAM_032970	0.0001167	48.0	COG1316@1|root,COG1316@2|Bacteria,1TQ9C@1239|Firmicutes,4HB29@91061|Bacilli,1ZB6K@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	ywtF_2	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
WZS3_k127_2225011_1	526218.Sterm_3224	2.04e-64	225.0	COG0406@1|root,COG0406@2|Bacteria,37BYT@32066|Fusobacteria	32066|Fusobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WZS3_k127_2225011_0	1232449.BAHV02000014_gene2071	3.057e-89	307.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,267R8@186813|unclassified Clostridiales	186801|Clostridia	C	FAD dependent oxidoreductase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
WZS3_k127_226909_4	1408422.JHYF01000003_gene825	1.787e-27	117.0	COG1863@1|root,COG1863@2|Bacteria,1VEJ0@1239|Firmicutes,24REY@186801|Clostridia,36MMM@31979|Clostridiaceae	186801|Clostridia	P	Na+/H+ ion antiporter subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
WZS3_k127_226909_7	293826.Amet_4158	1.482e-19	91.0	COG2212@1|root,COG2212@2|Bacteria,1VENR@1239|Firmicutes,24N3X@186801|Clostridia,36MD1@31979|Clostridiaceae	186801|Clostridia	P	Multiple resistance and pH regulation protein F (MrpF / PhaF)	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
WZS3_k127_226909_5	1408422.JHYF01000003_gene827	2.813e-27	117.0	COG1320@1|root,COG1320@2|Bacteria,1VHQ3@1239|Firmicutes,24RQT@186801|Clostridia,36KTJ@31979|Clostridiaceae	186801|Clostridia	P	Na+/H+ antiporter subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
WZS3_k127_226909_3	293826.Amet_4156	4.899e-28	114.0	COG1563@1|root,COG1563@2|Bacteria,1VGXY@1239|Firmicutes,24SS2@186801|Clostridia,36MD6@31979|Clostridiaceae	186801|Clostridia	P	Domain of unknown function (DUF4040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040
WZS3_k127_226909_6	293826.Amet_4155	1.944e-22	102.0	COG2111@1|root,COG2111@2|Bacteria,1VGFN@1239|Firmicutes,24SZ8@186801|Clostridia,36MY7@31979|Clostridiaceae	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_226909_1	1408422.JHYF01000003_gene830	3.812e-49	179.0	COG2111@1|root,COG2111@2|Bacteria,1V7V9@1239|Firmicutes,24EFK@186801|Clostridia,36GJN@31979|Clostridiaceae	186801|Clostridia	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	ko:K05566	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MnhB
WZS3_k127_226909_2	1408422.JHYF01000003_gene831	4.102e-43	160.0	COG1006@1|root,COG1006@2|Bacteria,1VBKW@1239|Firmicutes,24IY8@186801|Clostridia,36KEA@31979|Clostridiaceae	186801|Clostridia	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
WZS3_k127_226909_0	1408422.JHYF01000003_gene832	1.056e-174	561.0	COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,24AZH@186801|Clostridia,36E6V@31979|Clostridiaceae	186801|Clostridia	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568,ko:K12141	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
WZS3_k127_231343_0	445335.CBN_1446	2.82e-176	569.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E4P@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_231343_1	428127.EUBDOL_01147	7.468e-130	422.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,3VNWM@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
WZS3_k127_2390314_9	180332.JTGN01000005_gene2998	7.137e-28	117.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
WZS3_k127_2390314_8	1298920.KI911353_gene1835	1.004e-38	147.0	COG2832@1|root,COG2832@2|Bacteria,1V6I1@1239|Firmicutes,24QHU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
WZS3_k127_2390314_4	1122143.AUEG01000033_gene1183	1.659e-127	413.0	COG3752@1|root,COG3752@2|Bacteria,1V0FI@1239|Firmicutes,4HDGV@91061|Bacilli,27FPU@186828|Carnobacteriaceae	91061|Bacilli	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
WZS3_k127_2390314_6	1105031.HMPREF1141_2252	1.446e-119	395.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1UJ0B@1239|Firmicutes,25ESZ@186801|Clostridia	186801|Clostridia	T	SMART Metal-dependent phosphohydrolase, HD region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,PAS_3,PAS_4
WZS3_k127_2390314_5	1499684.CCNP01000018_gene838	1.15e-121	416.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,36G4E@31979|Clostridiaceae	186801|Clostridia	GKT	PRD domain	-	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
WZS3_k127_2390314_10	1122173.AXVL01000020_gene2250	4.863e-27	113.0	COG1447@1|root,COG1447@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIA
WZS3_k127_2390314_11	1196322.A370_04825	1.516e-25	108.0	COG1440@1|root,COG1440@2|Bacteria,1VDI5@1239|Firmicutes,25CRE@186801|Clostridia,36VVM@31979|Clostridiaceae	186801|Clostridia	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
WZS3_k127_2390314_3	1122173.AXVL01000020_gene2246	6.453e-131	431.0	COG1455@1|root,COG1455@2|Bacteria,378QZ@32066|Fusobacteria	2|Bacteria	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	ptcC	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
WZS3_k127_2390314_0	445974.CLORAM_02824	9.986e-209	660.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,3VP82@526524|Erysipelotrichia	1239|Firmicutes	G	COG COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
WZS3_k127_2390314_7	1395587.P364_0109505	3.202e-93	315.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,4HDPG@91061|Bacilli,26U5H@186822|Paenibacillaceae	91061|Bacilli	K	LysR family transcriptional regulator	rlrB	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WZS3_k127_2390314_1	994573.T472_0219380	8.987e-181	577.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_2390314_2	1499684.CCNP01000018_gene1867	6.216e-141	454.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,25B10@186801|Clostridia,36DKV@31979|Clostridiaceae	186801|Clostridia	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_2390314_12	1405.DJ92_83	4e-17	84.0	COG1695@1|root,COG1695@2|Bacteria,1VA1N@1239|Firmicutes,4HMNQ@91061|Bacilli,1ZI3V@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator PadR-like family	XK27_08645	-	-	-	-	-	-	-	-	-	-	-	PadR
WZS3_k127_2395698_3	1123009.AUID01000028_gene338	7.387e-21	94.0	COG1977@1|root,COG1977@2|Bacteria,1VIST@1239|Firmicutes,24QYP@186801|Clostridia,26C3V@186813|unclassified Clostridiales	186801|Clostridia	H	ThiS family	moaD	-	-	-	-	-	-	-	-	-	-	-	ThiS
WZS3_k127_2395698_0	1123009.AUID01000028_gene339	1.941e-298	924.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,26A1J@186813|unclassified Clostridiales	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	aor	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS09915	AFOR_C,AFOR_N
WZS3_k127_2395698_1	536227.CcarbDRAFT_3462	2.097e-81	284.0	COG0535@1|root,COG0535@2|Bacteria,1V0CR@1239|Firmicutes,24BIB@186801|Clostridia,36G4D@31979|Clostridiaceae	186801|Clostridia	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
WZS3_k127_2395698_5	445974.CLORAM_00725	7.705e-05	51.0	COG1714@1|root,COG1714@2|Bacteria,1V8T9@1239|Firmicutes,3VQTI@526524|Erysipelotrichia	526524|Erysipelotrichia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
WZS3_k127_2395698_4	1347392.CCEZ01000014_gene2717	2.581e-15	84.0	COG1714@1|root,COG1714@2|Bacteria,1V8T9@1239|Firmicutes,24MFH@186801|Clostridia,36K1N@31979|Clostridiaceae	186801|Clostridia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
WZS3_k127_2395698_2	1123009.AUID01000028_gene345	2.807e-64	230.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,268PC@186813|unclassified Clostridiales	186801|Clostridia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WZS3_k127_2418889_1	552396.HMPREF0863_01173	1.154e-29	123.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,3VQK7@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WZS3_k127_2418889_0	223926.28807392	3.836e-46	179.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RRV1@1236|Gammaproteobacteria,1Y2I9@135623|Vibrionales	135623|Vibrionales	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
WZS3_k127_2451095_0	1232446.BAIE02000055_gene3053	2.697e-19	92.0	COG1737@1|root,COG1737@2|Bacteria,1V00A@1239|Firmicutes,249MY@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
WZS3_k127_2451095_1	944481.JAFP01000001_gene1338	8.879e-19	93.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42QX2@68525|delta/epsilon subdivisions,2X2Q9@28221|Deltaproteobacteria,2M7MD@213113|Desulfurellales	28221|Deltaproteobacteria	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
WZS3_k127_2451095_2	938278.CAJO01000048_gene396	1.281e-18	87.0	COG4662@1|root,COG4662@2|Bacteria,1TRK7@1239|Firmicutes,249VG@186801|Clostridia,2695K@186813|unclassified Clostridiales	186801|Clostridia	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
WZS3_k127_2453109_0	999413.HMPREF1094_04088	1.615e-168	536.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,3VNZS@526524|Erysipelotrichia	526524|Erysipelotrichia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
WZS3_k127_2453109_1	1211819.CALK01000009_gene2771	2.495e-127	412.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,3VPEP@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
WZS3_k127_2461508_4	1408439.JHXW01000006_gene917	1.855e-61	215.0	COG0136@1|root,COG0136@2|Bacteria,378Y7@32066|Fusobacteria	32066|Fusobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
WZS3_k127_2461508_3	1449342.JQMR01000001_gene320	5.911e-64	228.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,4HBH4@91061|Bacilli	91061|Bacilli	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
WZS3_k127_2461508_0	1230342.CTM_10361	1.158e-140	457.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,36EUA@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
WZS3_k127_2461508_1	935948.KE386494_gene782	2.421e-127	421.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,42EZT@68295|Thermoanaerobacterales	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18870	Orn_Arg_deC_N,Orn_DAP_Arg_deC
WZS3_k127_2461508_5	1536774.H70357_27205	1.902e-36	147.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WZS3_k127_2461508_2	469596.HMPREF9488_00066	7.529e-66	235.0	COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,3VP29@526524|Erysipelotrichia	526524|Erysipelotrichia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WZS3_k127_2461508_6	649639.Bcell_1047	8.555e-31	126.0	COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli,1ZFPW@1386|Bacillus	91061|Bacilli	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
WZS3_k127_2461508_7	936375.HMPREF1152_0945	8.235e-05	46.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia	186801|Clostridia	O	dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
WZS3_k127_2503682_8	1507.HMPREF0262_01873	3.241e-05	48.0	COG1670@1|root,COG1670@2|Bacteria,1UYRS@1239|Firmicutes,249WX@186801|Clostridia,36I38@31979|Clostridiaceae	186801|Clostridia	J	acetyltransferase, gnat	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_2503682_1	908340.HMPREF9406_4022	9.677e-236	737.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,36DX4@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
WZS3_k127_2503682_2	1232449.BAHV02000006_gene926	9.334e-116	381.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,268I6@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
WZS3_k127_2503682_3	1232449.BAHV02000006_gene925	8.66e-98	327.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,268NT@186813|unclassified Clostridiales	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
WZS3_k127_2503682_0	545696.HOLDEFILI_00715	2.857e-269	840.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,3VP12@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	hflB	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
WZS3_k127_2503682_5	545696.HOLDEFILI_00716	3.954e-77	261.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,3VQ8X@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
WZS3_k127_2503682_6	1121874.KB892380_gene1607	8.464e-58	216.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,3VNRT@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
WZS3_k127_2503682_7	428127.EUBDOL_02190	3.767e-34	138.0	293C3@1|root,2ZQUQ@2|Bacteria,1V4DB@1239|Firmicutes,3VQMQ@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
WZS3_k127_2503682_4	1211819.CALK01000029_gene2077	2.302e-91	302.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,3VNYM@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Psort location Cytoplasmic, score 9.98	mbl	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
WZS3_k127_251434_1	656519.Halsa_0817	4.504e-64	229.0	COG1307@1|root,COG1461@1|root,COG1307@2|Bacteria,COG1461@2|Bacteria,1TR6J@1239|Firmicutes,24A8H@186801|Clostridia,3WC9D@53433|Halanaerobiales	186801|Clostridia	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
WZS3_k127_251434_0	1347392.CCEZ01000049_gene1402	3.428e-122	411.0	COG3275@1|root,COG3275@2|Bacteria,1VTXF@1239|Firmicutes,25E5Z@186801|Clostridia,36E2G@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02478,ko:K07704	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	5TM-5TMR_LYT,GAF_3,HATPase_c,His_kinase
WZS3_k127_2595172_3	1211844.CBLM010000078_gene2601	7.297e-49	176.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,3VNQ5@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Psort location Cytoplasmic, score 8.87	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
WZS3_k127_2595172_5	1397696.KK211189_gene1918	2.506e-37	145.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HMKT@91061|Bacilli,3WG0X@539002|Bacillales incertae sedis	91061|Bacilli	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WZS3_k127_2595172_2	246194.CHY_1707	5.152e-63	222.0	COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,24DQZ@186801|Clostridia,42FJH@68295|Thermoanaerobacterales	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
WZS3_k127_2595172_1	476272.RUMHYD_02820	1.166e-74	262.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24IEC@186801|Clostridia,3Y0MH@572511|Blautia	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
WZS3_k127_2595172_4	265729.GS18_0217165	2.657e-40	151.0	COG4269@1|root,COG4269@2|Bacteria,1VA3P@1239|Firmicutes,4HKWF@91061|Bacilli,1ZI0Q@1386|Bacillus	91061|Bacilli	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
WZS3_k127_2595172_0	665956.HMPREF1032_00096	1.286e-125	415.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,3WHCS@541000|Ruminococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
WZS3_k127_2595172_7	936589.HMPREF1521_1370	3.898e-16	85.0	COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes	1239|Firmicutes	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
WZS3_k127_2595172_6	457412.RSAG_03480	1.678e-26	109.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,3WGVR@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_2599188_2	1321784.HMPREF1987_01798	8.204e-09	57.0	COG1695@1|root,COG1695@2|Bacteria,1V9XX@1239|Firmicutes,24RE5@186801|Clostridia,25TXF@186804|Peptostreptococcaceae	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WZS3_k127_2599188_1	1347087.CBYO010000022_gene3437	1.308e-37	145.0	2CHCP@1|root,32S5R@2|Bacteria,1V3HI@1239|Firmicutes,4HGYA@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WZS3_k127_2599188_0	350688.Clos_0643	5.884e-104	349.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,36ECU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WZS3_k127_2604760_1	941639.BCO26_2926	2.114e-06	51.0	COG3457@1|root,COG3457@2|Bacteria,1TNYJ@1239|Firmicutes,4HBIA@91061|Bacilli,1ZF41@1386|Bacillus	91061|Bacilli	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
WZS3_k127_2604760_0	1347392.CCEZ01000004_gene766	5.8e-103	344.0	COG1181@1|root,COG1181@2|Bacteria,1TRW2@1239|Firmicutes,24F2R@186801|Clostridia,36IY4@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WZS3_k127_2605837_2	999413.HMPREF1094_03730	2.082e-99	327.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,3VPPU@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Family 4 glycosyl hydrolase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
WZS3_k127_2605837_0	999413.HMPREF1094_03729	4.139e-103	345.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,3VPNM@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_2605837_1	908340.HMPREF9406_3622	5.353e-100	335.0	COG2971@1|root,COG2971@2|Bacteria,1V0VG@1239|Firmicutes,24BFK@186801|Clostridia,36WXX@31979|Clostridiaceae	186801|Clostridia	G	BadF BadG BcrA BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WZS3_k127_2605837_3	1243664.CAVL020000027_gene804	1.824e-10	64.0	COG4997@1|root,COG4997@2|Bacteria,1VEG6@1239|Firmicutes,4HKMC@91061|Bacilli,1ZHZ3@1386|Bacillus	91061|Bacilli	S	phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
WZS3_k127_2617623_7	518637.EUBIFOR_00963	1.095e-65	229.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,3VNVJ@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
WZS3_k127_2617623_2	552396.HMPREF0863_00605	3.744e-102	341.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,3VPG5@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
WZS3_k127_2617623_1	1449343.JQLQ01000002_gene864	1.574e-109	362.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli,27FC5@186828|Carnobacteriaceae	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS3_k127_2617623_4	562970.Btus_1710	5.492e-80	282.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,27891@186823|Alicyclobacillaceae	91061|Bacilli	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WZS3_k127_2617623_3	1158606.I579_00165	7.437e-81	283.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli,4AZ9I@81852|Enterococcaceae	91061|Bacilli	E	Receptor family ligand binding region	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
WZS3_k127_2617623_0	545696.HOLDEFILI_02329	2.546e-161	520.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,3VQ3H@526524|Erysipelotrichia	526524|Erysipelotrichia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_2617623_13	1461580.CCAS010000118_gene4584	3.413e-07	53.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli,1ZJWT@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2617623_9	1298920.KI911353_gene3829	2.327e-48	178.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,2218F@1506553|Lachnoclostridium	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WZS3_k127_2617623_8	1232449.BAHV02000010_gene2488	1.159e-63	220.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,26924@186813|unclassified Clostridiales	186801|Clostridia	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
WZS3_k127_2617623_5	545696.HOLDEFILI_02357	2.765e-75	254.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,3VQ7B@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
WZS3_k127_2617623_12	1232452.BAIB02000002_gene133	1.171e-09	64.0	2E9W7@1|root,3341X@2|Bacteria,1VG1X@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3887)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887
WZS3_k127_2617623_10	1230342.CTM_18834	5.8e-32	134.0	COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,24JI9@186801|Clostridia,36K76@31979|Clostridiaceae	186801|Clostridia	S	Putative membrane peptidase family (DUF2324)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
WZS3_k127_2617623_6	1232449.BAHV02000010_gene2486	4.029e-71	248.0	COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,24ATG@186801|Clostridia	186801|Clostridia	E	Histidinol phosphate phosphatase, HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
WZS3_k127_2617623_11	1121874.KB892378_gene448	1.18e-18	87.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,3VP7T@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
WZS3_k127_2618796_0	1203606.HMPREF1526_03144	1.169e-151	486.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36F8M@31979|Clostridiaceae	186801|Clostridia	C	formate acetyltransferase	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
WZS3_k127_2646262_1	871968.DESME_05400	4.387e-33	133.0	2AJWE@1|root,31AJA@2|Bacteria,1VATY@1239|Firmicutes,24MXD@186801|Clostridia,265CR@186807|Peptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2646262_0	428125.CLOLEP_00419	5.845e-67	233.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,3WGU2@541000|Ruminococcaceae	186801|Clostridia	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS3_k127_2671880_0	717605.Theco_1633	1.393e-144	463.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,4HC0W@91061|Bacilli,26RUI@186822|Paenibacillaceae	91061|Bacilli	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	yajO	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_2671880_2	29581.BW37_05113	3.181e-12	67.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,2VYEK@28216|Betaproteobacteria,4757D@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2671880_1	138119.DSY1543	1.879e-13	75.0	COG0762@1|root,COG0762@2|Bacteria,1VN1M@1239|Firmicutes,24X1E@186801|Clostridia,265M7@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
WZS3_k127_2675001_0	938293.CAJU020000003_gene813	1.14e-132	434.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,22G34@1570339|Peptoniphilaceae	186801|Clostridia	L	cog cog3328	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
WZS3_k127_2677411_3	545697.HMPREF0216_00589	4.688e-91	301.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,24A0K@186801|Clostridia,36DJ3@31979|Clostridiaceae	186801|Clostridia	G	PTS system mannose fructose sorbose family IID component	agaD	-	-	ko:K02747	ko00052,ko02060,map00052,map02060	M00277	R08366	RC00017	ko00000,ko00001,ko00002,ko02000	4.A.6.1.4	-	-	EIID-AGA
WZS3_k127_2677411_1	883114.HMPREF9709_01476	1.352e-101	336.0	COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,24CSB@186801|Clostridia,22H4P@1570339|Peptoniphilaceae	186801|Clostridia	G	PTS system sorbose-specific iic component	agaC	-	-	ko:K02746	ko00052,ko02060,map00052,map02060	M00277	R08366	RC00017	ko00000,ko00001,ko00002,ko02000	4.A.6.1.4	-	-	EII-Sor
WZS3_k127_2677411_4	1121333.JMLH01000002_gene187	7.964e-73	249.0	COG3444@1|root,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,3VQ9H@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score	-	-	-	ko:K02745	ko00052,ko02060,map00052,map02060	M00277	R08366	RC00017	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4	-	-	PTSIIB_sorb
WZS3_k127_2677411_2	428127.EUBDOL_02279	4.673e-96	327.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,3VPBX@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Transcriptional regulator, AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
WZS3_k127_2677411_0	394503.Ccel_1008	2.298e-143	465.0	COG4573@1|root,COG4573@2|Bacteria,1TQDN@1239|Firmicutes,24A03@186801|Clostridia,36EB9@31979|Clostridiaceae	186801|Clostridia	G	Tagatose 6 phosphate kinase	-	-	-	ko:K16371	ko00052,ko01100,map00052,map01100	-	R01069	RC00438,RC00439	ko00000,ko00001	-	-	-	Tagatose_6_P_K
WZS3_k127_2687198_0	1410668.JNKC01000005_gene2409	7.019e-136	444.0	COG0651@1|root,COG0651@2|Bacteria,1TREH@1239|Firmicutes,248TK@186801|Clostridia,36EZ5@31979|Clostridiaceae	186801|Clostridia	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WZS3_k127_2691276_0	545696.HOLDEFILI_00643	9.624e-65	233.0	COG0449@1|root,COG0449@2|Bacteria,1V20M@1239|Firmicutes,3VQBT@526524|Erysipelotrichia	526524|Erysipelotrichia	M	SIS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SIS
WZS3_k127_2691276_1	1391646.AVSU01000092_gene427	6.779e-12	67.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,24A0K@186801|Clostridia	186801|Clostridia	G	PTS system mannose fructose sorbose family IID component	agaD	-	-	ko:K02747	ko00052,ko02060,map00052,map02060	M00277	R08366	RC00017	ko00000,ko00001,ko00002,ko02000	4.A.6.1.4	-	-	EIID-AGA
WZS3_k127_2692603_2	1408306.JHXX01000001_gene2239	1.621e-22	109.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,4BXUK@830|Butyrivibrio	186801|Clostridia	NU	Type II secretion system (T2SS), protein F	gspF	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
WZS3_k127_2692603_0	999413.HMPREF1094_04305	6.731e-70	248.0	COG1305@1|root,COG1305@2|Bacteria,1TP7G@1239|Firmicutes,3VNTF@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
WZS3_k127_2692603_1	929556.Solca_0050	8.867e-54	209.0	COG1470@1|root,COG3209@1|root,COG4932@1|root,COG1470@2|Bacteria,COG3209@2|Bacteria,COG4932@2|Bacteria,4PKBQ@976|Bacteroidetes,1J0N1@117747|Sphingobacteriia	976|Bacteroidetes	M	conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SprB
WZS3_k127_2705333_1	555088.DealDRAFT_0207	1.383e-89	299.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,SRP54
WZS3_k127_2705333_0	1121346.KB899868_gene3125	1.107e-118	391.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,26QVH@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl transferase family 1	yjcA	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran,ABC_tran_Xtn
WZS3_k127_2720239_2	411463.EUBVEN_02585	1.709e-10	68.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,24B3M@186801|Clostridia,25XGP@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_2720239_0	1033810.HLPCO_002771	5.561e-32	137.0	COG0561@1|root,COG0561@2|Bacteria,2NQYP@2323|unclassified Bacteria	2|Bacteria	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	4HBT,Hydrolase_3
WZS3_k127_2720239_1	158190.SpiGrapes_2320	1.514e-19	96.0	COG2211@1|root,COG2211@2|Bacteria,2J6VC@203691|Spirochaetes	203691|Spirochaetes	G	TIGRFAM sugar (Glycoside-Pentoside-Hexuronide) transporter	-	-	-	ko:K11104,ko:K16209,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
WZS3_k127_2721688_5	545696.HOLDEFILI_02113	2.221e-10	66.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,3VPSN@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location Cytoplasmic, score	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
WZS3_k127_2721688_2	457396.CSBG_03003	5.263e-72	246.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,36HY3@31979|Clostridiaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rotA	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
WZS3_k127_2721688_3	1410674.JNKU01000005_gene1599	2.325e-47	187.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WZS3_k127_2721688_1	632245.CLP_2413	2.359e-78	271.0	COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,24A7U@186801|Clostridia,36F2Z@31979|Clostridiaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
WZS3_k127_2721688_4	1211819.CALK01000004_gene2355	7.954e-32	130.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,3VR8F@526524|Erysipelotrichia	526524|Erysipelotrichia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2721688_0	908340.HMPREF9406_3132	1.77e-233	740.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,36DS9@31979|Clostridiaceae	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
WZS3_k127_2732388_3	1121129.KB903359_gene2542	6.302e-30	121.0	COG0183@1|root,COG0183@2|Bacteria,4NE3Q@976|Bacteroidetes,2FQIE@200643|Bacteroidia,22X92@171551|Porphyromonadaceae	976|Bacteroidetes	I	Thiolase, C-terminal domain	atoB	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS3_k127_2732388_0	1536769.P40081_09050	3.129e-109	364.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,26RRQ@186822|Paenibacillaceae	91061|Bacilli	G	Mannitol-1-phosphate	mtlD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
WZS3_k127_2732388_2	1211844.CBLM010000041_gene2766	9.237e-55	200.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1V77P@1239|Firmicutes,3VQKA@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2,PTS_IIB
WZS3_k127_2732388_1	1235796.C815_01788	1.573e-72	263.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes	1239|Firmicutes	GKT	transcriptional antiterminator	licR	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
WZS3_k127_273618_0	926561.KB900617_gene1603	1.434e-107	362.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WBFC@53433|Halanaerobiales	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,Glyco_hydro_3,Glyco_hydro_3_C
WZS3_k127_2749254_1	1485543.JMME01000002_gene1597	6.592e-34	132.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,4H29V@909932|Negativicutes	909932|Negativicutes	C	Radical SAM domain protein	proB2	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WZS3_k127_2749254_0	1280666.ATVS01000017_gene457	2.315e-117	391.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia,4BXBW@830|Butyrivibrio	186801|Clostridia	S	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
WZS3_k127_2749254_2	1034347.CAHJ01000054_gene128	6.462e-22	99.0	COG3439@1|root,COG3439@2|Bacteria,1VA5R@1239|Firmicutes,4HITT@91061|Bacilli,1ZH19@1386|Bacillus	91061|Bacilli	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
WZS3_k127_2763118_2	755731.Clo1100_0058	1.014e-23	103.0	COG1597@1|root,COG1597@2|Bacteria,1V1DP@1239|Firmicutes,25CN2@186801|Clostridia,36HD9@31979|Clostridiaceae	186801|Clostridia	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WZS3_k127_2763118_1	1123405.AUMM01000011_gene1348	3.026e-78	275.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli,26NCM@186821|Sporolactobacillaceae	91061|Bacilli	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WZS3_k127_2763118_0	658659.HMPREF0983_03160	2.36e-178	569.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,3VNRN@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
WZS3_k127_281257_2	714961.BFZC1_03408	1.03e-15	80.0	COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HQZW@91061|Bacilli,3IXDJ@400634|Lysinibacillus	91061|Bacilli	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
WZS3_k127_281257_0	1122173.AXVL01000005_gene208	2.136e-41	158.0	COG2426@1|root,COG2426@2|Bacteria,37C0J@32066|Fusobacteria	32066|Fusobacteria	S	small multi-drug export	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
WZS3_k127_281257_3	994573.T472_0206470	0.0001686	48.0	COG1933@1|root,COG1933@2|Bacteria,1UM3E@1239|Firmicutes,24KDU@186801|Clostridia,36VE2@31979|Clostridiaceae	186801|Clostridia	L	Double zinc ribbon	-	-	-	-	-	-	-	-	-	-	-	-	DZR
WZS3_k127_281257_1	656519.Halsa_1406	8.583e-23	106.0	COG3307@1|root,COG3307@2|Bacteria,1V6KK@1239|Firmicutes,25BNJ@186801|Clostridia,3WBMH@53433|Halanaerobiales	186801|Clostridia	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WZS3_k127_2817577_3	908340.HMPREF9406_3552	5.479e-98	329.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,36DR2@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WZS3_k127_2817577_2	903814.ELI_1608	1.402e-101	337.0	COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,25E47@186801|Clostridia,25ZKH@186806|Eubacteriaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
WZS3_k127_2817577_4	999411.HMPREF1092_00854	2.324e-89	302.0	COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,36DEI@31979|Clostridiaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
WZS3_k127_2817577_0	445971.ANASTE_02103	4.506e-185	589.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,25V5Q@186806|Eubacteriaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, biotin carboxylase subunit	accC	-	6.3.4.14,6.3.4.6,6.4.1.2	ko:K01941,ko:K01961	ko00061,ko00220,ko00620,ko00640,ko00720,ko00791,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00220,map00620,map00640,map00720,map00791,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R00774,R04385	RC00040,RC00253,RC00367,RC00378	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
WZS3_k127_2817577_5	411465.PEPMIC_00889	1.99e-32	130.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,22J1X@1570339|Peptoniphilaceae	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
WZS3_k127_2817577_7	445971.ANASTE_02101	7.341e-24	103.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
WZS3_k127_2817577_6	580327.Tthe_0632	1.346e-24	113.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,42F0N@68295|Thermoanaerobacterales	186801|Clostridia	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
WZS3_k127_2817577_1	1232449.BAHV02000010_gene3133	1.66e-129	420.0	COG1142@1|root,COG4624@1|root,COG1142@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,2688B@186813|unclassified Clostridiales	186801|Clostridia	C	Iron only hydrogenase large subunit, C-terminal domain	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4
WZS3_k127_2825622_0	545696.HOLDEFILI_01836	2.348e-131	427.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,3VNWN@526524|Erysipelotrichia	526524|Erysipelotrichia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A
WZS3_k127_2825622_1	1232449.BAHV02000011_gene2147	5.34e-66	234.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WZS3_k127_2825622_2	908340.HMPREF9406_0515	5.382e-29	124.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,36J0Z@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WZS3_k127_282899_0	1487921.DP68_16560	7.019e-47	173.0	COG0491@1|root,COG0491@2|Bacteria,1TSU6@1239|Firmicutes,24DDT@186801|Clostridia,36FFX@31979|Clostridiaceae	186801|Clostridia	S	metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS3_k127_282899_1	86416.Clopa_2106	5.888e-38	147.0	COG1846@1|root,COG1846@2|Bacteria,1V71W@1239|Firmicutes,25CVF@186801|Clostridia	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_282899_3	1321778.HMPREF1982_01375	5.918e-26	111.0	COG3976@1|root,COG3976@2|Bacteria,1VNC5@1239|Firmicutes	1239|Firmicutes	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
WZS3_k127_282899_2	931626.Awo_c04310	2.578e-27	115.0	COG4635@1|root,COG4635@2|Bacteria,1U0AY@1239|Firmicutes,25P9E@186801|Clostridia,25Z7J@186806|Eubacteriaceae	186801|Clostridia	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
WZS3_k127_2840567_1	552396.HMPREF0863_00733	3.615e-119	385.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,3VNW9@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WZS3_k127_2840567_0	545696.HOLDEFILI_03524	1.33e-141	456.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,3VPSK@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Psort location Cytoplasmic, score	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
WZS3_k127_2840567_2	469616.FMAG_02254	5.539e-06	52.0	COG0531@1|root,COG0531@2|Bacteria,379SQ@32066|Fusobacteria	32066|Fusobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WZS3_k127_2844079_0	887327.HMPREF0476_0188	4.939e-21	96.0	COG4487@1|root,COG4487@2|Bacteria,1R5G1@1224|Proteobacteria,2VJ5S@28216|Betaproteobacteria,2KQHQ@206351|Neisseriales	206351|Neisseriales	S	Uncharacterized protein conserved in bacteria (DUF2130)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2130
WZS3_k127_2844079_1	908340.HMPREF9406_3614	1.49e-16	79.0	COG2159@1|root,COG2159@2|Bacteria,1VX3V@1239|Firmicutes,24XSC@186801|Clostridia	186801|Clostridia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WZS3_k127_2855982_0	857293.CAAU_0628	4.275e-194	614.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS3_k127_2855982_1	574375.BAGA_09980	4.249e-114	378.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli,1ZB9N@1386|Bacillus	91061|Bacilli	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
WZS3_k127_2855982_2	1410612.JNKO01000001_gene2661	9.173e-73	251.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,2PR4S@265975|Oribacterium	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS3_k127_2856397_1	1246.JMEA01000003_gene986	4.619e-09	57.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,4AXI7@81850|Leuconostocaceae	91061|Bacilli	G	3-carboxymuconate cyclase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
WZS3_k127_2856397_0	518637.EUBIFOR_02550	6.972e-78	275.0	COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,3VNUD@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Transposase, IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
WZS3_k127_2861682_0	428127.EUBDOL_01072	7.414e-127	419.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,3VP48@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS3_k127_2861682_3	908340.HMPREF9406_1607	3.45e-12	75.0	2ENNP@1|root,33GA1@2|Bacteria,1VQ27@1239|Firmicutes,252XP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2861682_4	1232449.BAHV02000011_gene2134	2.604e-09	67.0	2EC4G@1|root,3363C@2|Bacteria,1VJSG@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_2861682_1	1121874.KB892377_gene952	4.042e-114	379.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,3VPC3@526524|Erysipelotrichia	526524|Erysipelotrichia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WZS3_k127_2861682_2	1211819.CALK01000004_gene2291	2.047e-53	192.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,3VQFH@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
WZS3_k127_286263_2	650150.ERH_1098	7.642e-19	90.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,3VQAE@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WZS3_k127_286263_1	1211819.CALK01000008_gene2677	2.365e-180	582.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,3VNS5@526524|Erysipelotrichia	526524|Erysipelotrichia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
WZS3_k127_286263_0	1211819.CALK01000008_gene2678	8.311e-193	626.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,3VNRS@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
WZS3_k127_286263_3	545696.HOLDEFILI_01987	8.678e-18	93.0	COG1286@1|root,COG1286@2|Bacteria,1VHHC@1239|Firmicutes,3VRUH@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Colicin V production protein	cvpA	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
WZS3_k127_2868396_1	697281.Mahau_1367	4.64e-26	112.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,42EJU@68295|Thermoanaerobacterales	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
WZS3_k127_2868396_0	871963.Desdi_0136	4.3e-190	607.0	COG0433@1|root,COG0433@2|Bacteria,1TR1F@1239|Firmicutes,24BT8@186801|Clostridia	186801|Clostridia	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
WZS3_k127_2868396_2	502558.EGYY_12310	2.689e-23	103.0	COG1971@1|root,COG1971@2|Bacteria,2GNBU@201174|Actinobacteria,4CVMV@84998|Coriobacteriia	84998|Coriobacteriia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
WZS3_k127_289238_2	552396.HMPREF0863_00809	8.353e-72	251.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,3VNQN@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS3_k127_289238_1	1123299.AUKZ01000010_gene1574	1.418e-159	515.0	COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli	91061|Bacilli	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
WZS3_k127_289238_0	1232449.BAHV02000012_gene2192	3.96e-264	831.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,267TJ@186813|unclassified Clostridiales	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
WZS3_k127_289238_3	243274.THEMA_03475	1.365e-45	169.0	COG0758@1|root,COG0758@2|Bacteria,2GCZR@200918|Thermotogae	200918|Thermotogae	L	DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,TrmB
WZS3_k127_2912327_2	891968.Anamo_1213	1.141e-19	89.0	COG2148@1|root,COG2148@2|Bacteria,3TB41@508458|Synergistetes	508458|Synergistetes	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
WZS3_k127_2912327_1	742723.HMPREF9477_00064	5.461e-32	134.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,27K11@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
WZS3_k127_2912327_0	293826.Amet_1622	7.546e-96	323.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,36DRG@31979|Clostridiaceae	186801|Clostridia	E	amidohydrolase	dapL	-	3.5.1.47	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R02733	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_2913533_1	545696.HOLDEFILI_03683	3.176e-24	103.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,3VRVA@526524|Erysipelotrichia	526524|Erysipelotrichia	J	RNA-binding protein, YhbY family	-	-	-	-	-	-	-	-	-	-	-	-	CRS1_YhbY
WZS3_k127_2913533_0	908340.HMPREF9406_1518	6.027e-84	289.0	COG1057@1|root,COG1713@1|root,COG1057@2|Bacteria,COG1713@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,36I7Z@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
WZS3_k127_2913533_3	1232428.CAVO010000016_gene893	2.097e-18	88.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4H585@909932|Negativicutes	909932|Negativicutes	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
WZS3_k127_2913533_2	428127.EUBDOL_01290	1.266e-22	107.0	COG0500@1|root,COG2226@2|Bacteria,1TQUF@1239|Firmicutes,3VQGE@526524|Erysipelotrichia	526524|Erysipelotrichia	Q	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
WZS3_k127_2913533_4	1319815.HMPREF0202_00508	1.034e-07	55.0	COG0775@1|root,COG0775@2|Bacteria,3784Q@32066|Fusobacteria	32066|Fusobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_2924766_1	656519.Halsa_0316	1.62e-98	344.0	COG2203@1|root,COG3835@1|root,COG2203@2|Bacteria,COG3835@2|Bacteria,1V6N6@1239|Firmicutes,24Q7R@186801|Clostridia	186801|Clostridia	KT	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_30
WZS3_k127_2924766_2	101510.RHA1_ro03501	1.976e-56	209.0	COG4932@1|root,COG4932@2|Bacteria,2GJ4T@201174|Actinobacteria	201174|Actinobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Collagen,DUF3494
WZS3_k127_2924766_3	545693.BMQ_3150	1.517e-40	158.0	COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli,1ZFRS@1386|Bacillus	91061|Bacilli	M	COG3764 Sortase (surface protein transpeptidase)	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
WZS3_k127_2924766_4	1139996.OMQ_01172	1.575e-28	117.0	COG2846@1|root,COG2846@2|Bacteria,1VHK9@1239|Firmicutes,4IRYX@91061|Bacilli	91061|Bacilli	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	-
WZS3_k127_2924766_0	994573.T472_0207665	7.451e-180	578.0	COG1233@1|root,COG1233@2|Bacteria,1UU71@1239|Firmicutes	1239|Firmicutes	Q	Phytoene dehydrogenase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
WZS3_k127_2928329_4	1408422.JHYF01000009_gene2083	1.484e-81	274.0	COG1131@1|root,COG1131@2|Bacteria,1TRNT@1239|Firmicutes,24B5J@186801|Clostridia,36FNP@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_2928329_8	1408422.JHYF01000009_gene2084	5.533e-38	150.0	COG1309@1|root,COG1309@2|Bacteria,1V8M2@1239|Firmicutes,24J7T@186801|Clostridia,36K2V@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_2928329_3	1499689.CCNN01000015_gene3374	1.453e-116	388.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,36FFH@31979|Clostridiaceae	186801|Clostridia	E	aminopeptidase	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
WZS3_k127_2928329_1	1211819.CALK01000032_gene3018	1.144e-150	486.0	COG1078@1|root,COG1078@2|Bacteria,1TPVB@1239|Firmicutes,3VNUU@526524|Erysipelotrichia	526524|Erysipelotrichia	S	HD domain protein	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
WZS3_k127_2928329_5	1211819.CALK01000032_gene3070	2.073e-66	231.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,3VQMV@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	-	-	-	-	-	-	-	-	-	-	YgbB
WZS3_k127_2928329_6	158189.SpiBuddy_1163	6.416e-60	209.0	COG0394@1|root,COG0394@2|Bacteria	2|Bacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
WZS3_k127_2928329_2	398512.JQKC01000001_gene2396	1.327e-121	394.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3WH4C@541000|Ruminococcaceae	186801|Clostridia	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
WZS3_k127_2928329_7	1211819.CALK01000047_gene1774	9.851e-46	167.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,3VQZQ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
WZS3_k127_2928329_0	1211819.CALK01000047_gene1770	6.298e-164	522.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,3VNPJ@526524|Erysipelotrichia	526524|Erysipelotrichia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WZS3_k127_2937322_5	457396.CSBG_01150	3.827e-53	195.0	COG0531@1|root,COG0531@2|Bacteria,1TQ48@1239|Firmicutes,248C7@186801|Clostridia,36GTH@31979|Clostridiaceae	186801|Clostridia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WZS3_k127_2937322_4	545696.HOLDEFILI_03525	2.464e-64	224.0	COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,3VQH0@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Belongs to the ArsC family	-	-	-	ko:K16509	-	-	-	-	ko00000	-	-	-	ArsC
WZS3_k127_2937322_1	545696.HOLDEFILI_03526	4.815e-163	522.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,3VNUW@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
WZS3_k127_2937322_6	1504823.CCMM01000013_gene2368	1.066e-23	109.0	COG1266@1|root,COG1266@2|Bacteria,2NRNK@2323|unclassified Bacteria	2|Bacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
WZS3_k127_2937322_0	545696.HOLDEFILI_03528	4.433e-242	768.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,3VPFK@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,UvrD_C_2
WZS3_k127_2937322_2	552396.HMPREF0863_01266	3.09e-108	355.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,3VPWK@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_2937322_3	720554.Clocl_1003	2.167e-74	271.0	28IUJ@1|root,2Z8T8@2|Bacteria,1W5W7@1239|Firmicutes,25E72@186801|Clostridia,3WG7C@541000|Ruminococcaceae	186801|Clostridia	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
WZS3_k127_2937322_8	697284.ERIC2_c07900	9.356e-09	63.0	COG1846@1|root,COG1846@2|Bacteria,1V8EW@1239|Firmicutes,4HMWY@91061|Bacilli,26WXY@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
WZS3_k127_2937322_7	580331.Thit_0217	6.149e-18	97.0	COG0845@1|root,COG0845@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia,42G7A@68295|Thermoanaerobacterales	186801|Clostridia	M	secretion protein HlyD	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
WZS3_k127_2937538_0	545696.HOLDEFILI_00743	4.852e-138	442.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,3VPIA@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
WZS3_k127_2937538_1	999413.HMPREF1094_01236	6.31e-73	255.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,3VP4N@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
WZS3_k127_2937538_2	1211819.CALK01000029_gene2088	3.71e-17	83.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,3VNZ8@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WZS3_k127_297688_1	1211819.CALK01000050_gene1517	9.885e-60	208.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,3VPM6@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WZS3_k127_297688_2	1211819.CALK01000050_gene1516	2.27e-25	106.0	COG2501@1|root,COG2501@2|Bacteria,1VEJ2@1239|Firmicutes,3VRYJ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	S4 domain	yaaA	-	-	-	-	-	-	-	-	-	-	-	S4_2
WZS3_k127_297688_0	1121874.KB892380_gene1722	3.508e-83	287.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,3VPZG@526524|Erysipelotrichia	526524|Erysipelotrichia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WZS3_k127_2978109_1	545696.HOLDEFILI_02625	3.259e-25	115.0	COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,3VQT3@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Peptidase, U32 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
WZS3_k127_2978109_0	562982.HMPREF0432_01090	9.078e-72	253.0	COG0477@1|root,COG2814@2|Bacteria,1TWWZ@1239|Firmicutes,4HEV3@91061|Bacilli,3WE7Q@539002|Bacillales incertae sedis	91061|Bacilli	EGP	Major Facilitator Superfamily	yxlH	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS3_k127_3000612_1	478749.BRYFOR_09003	1.806e-09	60.0	2B9Z2@1|root,323CP@2|Bacteria,1VE7M@1239|Firmicutes,25DYU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ToxN_toxin
WZS3_k127_3000612_0	1163671.JAGI01000002_gene2310	7.56e-64	222.0	COG2267@1|root,COG2267@2|Bacteria,1UZ5S@1239|Firmicutes,25CEG@186801|Clostridia,36WUK@31979|Clostridiaceae	186801|Clostridia	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
WZS3_k127_3004470_1	935948.KE386495_gene2016	2.166e-32	130.0	COG1014@1|root,COG1014@2|Bacteria,1UYYG@1239|Firmicutes,24I53@186801|Clostridia,42GAS@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Pyruvate ketoisovalerate oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,Rubrerythrin
WZS3_k127_3004470_0	1033810.HLPCO_002281	6.383e-89	297.0	COG1013@1|root,COG1013@2|Bacteria,2NNMC@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00175,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
WZS3_k127_3021585_2	1232449.BAHV02000018_gene1721	6.232e-106	347.0	COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,247MD@186801|Clostridia	186801|Clostridia	S	sugar-specific permease SgaT UlaA	ulaA	-	-	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.7.1	-	-	EIIC-GAT
WZS3_k127_3021585_4	1232449.BAHV02000018_gene1720	2.905e-41	154.0	COG3414@1|root,COG3414@2|Bacteria,1VHNP@1239|Firmicutes,24QSA@186801|Clostridia	186801|Clostridia	G	PTS system, Lactose Cellobiose specific IIB subunit	sgaB	-	2.7.1.194	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	PTS_IIB
WZS3_k127_3021585_1	999413.HMPREF1094_01515	7.579e-108	361.0	28IPH@1|root,2Z8PG@2|Bacteria,1TREB@1239|Firmicutes,3VP7D@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3021585_3	994573.T472_0213600	3.716e-102	337.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,36DCJ@31979|Clostridiaceae	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00590	Aldolase_II
WZS3_k127_3021585_0	1232449.BAHV02000019_gene1408	7.806e-111	365.0	COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,247T6@186801|Clostridia	186801|Clostridia	G	hexulose-6-phosphate isomerase	sgbU	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
WZS3_k127_3021585_5	546269.HMPREF0389_01123	1.558e-39	149.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25QJW@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
WZS3_k127_3028621_0	931626.Awo_c05550	8.935e-183	585.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,25WZN@186806|Eubacteriaceae	186801|Clostridia	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WZS3_k127_3028621_3	1487921.DP68_16000	1.861e-29	123.0	2EDRU@1|root,337MD@2|Bacteria,1VIEE@1239|Firmicutes,24P45@186801|Clostridia,36KTK@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3028621_2	1121324.CLIT_10c01430	2.834e-37	143.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
WZS3_k127_3028621_4	1121324.CLIT_10c01440	6.041e-19	87.0	COG1918@1|root,COG1918@2|Bacteria,1VHBI@1239|Firmicutes,24T0C@186801|Clostridia	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
WZS3_k127_3028621_1	1410668.JNKC01000003_gene482	2.763e-108	360.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,36DF0@31979|Clostridiaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WZS3_k127_303657_2	1121947.AUHK01000014_gene672	0.0001545	47.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,22GGQ@1570339|Peptoniphilaceae	186801|Clostridia	G	alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10,3.2.1.70	ko:K01176,ko:K01182,ko:K01215	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
WZS3_k127_303657_1	1158612.I580_02021	7.866e-25	109.0	COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes,4HJXK@91061|Bacilli,4B102@81852|Enterococcaceae	91061|Bacilli	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
WZS3_k127_303657_0	1158609.I586_00634	1.215e-86	293.0	COG1307@1|root,COG1307@2|Bacteria,1TYCV@1239|Firmicutes,4HD8F@91061|Bacilli,4AZQW@81852|Enterococcaceae	91061|Bacilli	K	Uncharacterised protein, DegV family COG1307	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_3041039_7	1121874.KB892380_gene1597	1.68e-09	59.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,3VQH3@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WZS3_k127_3041039_2	1211819.CALK01000023_gene1689	5.25e-31	124.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,3VRFG@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
WZS3_k127_3041039_1	1123263.AUKY01000144_gene655	9.244e-69	242.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,3VQMM@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
WZS3_k127_3041039_6	1211819.CALK01000016_gene620	5.946e-14	79.0	2EA26@1|root,3347D@2|Bacteria,1VIIA@1239|Firmicutes,3VRSP@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
WZS3_k127_3041039_3	1410668.JNKC01000001_gene1164	9.257e-27	115.0	COG4720@1|root,COG4720@2|Bacteria,1UNF7@1239|Firmicutes,25H1P@186801|Clostridia,36V79@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3041039_5	545696.HOLDEFILI_00567	3.244e-21	99.0	COG2096@1|root,COG2096@2|Bacteria	2|Bacteria	S	cob(I)yrinic acid a,c-diamide adenosyltransferase activity	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.2.1.88,1.5.5.2,2.5.1.17	ko:K00798,ko:K13821	ko00250,ko00330,ko00860,ko01100,ko01110,ko01130,map00250,map00330,map00860,map01100,map01110,map01130	M00122	R00245,R00707,R00708,R01253,R01492,R04444,R04445,R05051,R05220,R07268	RC00080,RC00083,RC00216,RC00242,RC00255,RC00533	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Cob_adeno_trans
WZS3_k127_3041039_0	1033810.HLPCO_001396	0.0	1129.0	COG0209@1|root,COG0209@2|Bacteria,2NNVF@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
WZS3_k127_3041039_4	994573.T472_0215670	4.276e-23	106.0	COG1633@1|root,COG1633@2|Bacteria,1VAXV@1239|Firmicutes,24KX7@186801|Clostridia,36MJ6@31979|Clostridiaceae	186801|Clostridia	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
WZS3_k127_3063671_1	1449343.JQLQ01000002_gene1855	3.781e-24	106.0	2DWRV@1|root,341M8@2|Bacteria,1VY75@1239|Firmicutes,4HXPM@91061|Bacilli,27HG5@186828|Carnobacteriaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3063671_3	933115.GPDM_13781	1.574e-05	54.0	COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,4HCBK@91061|Bacilli,26E8H@186818|Planococcaceae	91061|Bacilli	S	UPF0316 protein	yebE	-	-	-	-	-	-	-	-	-	-	-	DUF2179
WZS3_k127_3063671_0	411489.CLOL250_01354	7.684e-29	117.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,36NPA@31979|Clostridiaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
WZS3_k127_3063671_2	877415.JNJQ01000012_gene586	1.9e-10	62.0	COG1670@1|root,COG1670@2|Bacteria,1V5GI@1239|Firmicutes,3VR2C@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_3104184_0	1232443.BAIA02000127_gene1142	3.35e-111	366.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia,26A6Y@186813|unclassified Clostridiales	186801|Clostridia	EG	GntP family permease	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
WZS3_k127_3104184_1	742733.HMPREF9469_03825	9.757e-29	121.0	COG3835@1|root,COG3835@2|Bacteria,1TTCF@1239|Firmicutes,24CMJ@186801|Clostridia,21YIM@1506553|Lachnoclostridium	186801|Clostridia	KT	Putative sugar diacid recognition	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
WZS3_k127_3135492_2	1304866.K413DRAFT_2356	8.302e-37	140.0	COG1670@1|root,COG1670@2|Bacteria,1UYRS@1239|Firmicutes,249WX@186801|Clostridia,36I38@31979|Clostridiaceae	186801|Clostridia	J	acetyltransferase, gnat	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_3135492_1	1185653.A1A1_16605	1.087e-90	313.0	COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,26EJX@186818|Planococcaceae	91061|Bacilli	CP	permease	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS3_k127_3135492_0	1301100.HG529275_gene1564	3.035e-108	358.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,249YC@186801|Clostridia,36VFE@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WZS3_k127_3141659_2	660470.Theba_2261	1.218e-58	205.0	2DH26@1|root,2ZY4Z@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
WZS3_k127_3141659_1	445971.ANASTE_00614	1.368e-73	254.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,25W26@186806|Eubacteriaceae	186801|Clostridia	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
WZS3_k127_3141659_3	1121934.AUDX01000008_gene2493	6.332e-08	60.0	COG1846@1|root,COG1846@2|Bacteria,2GYET@201174|Actinobacteria,4FRVW@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WZS3_k127_3141659_0	1384066.JAGT01000001_gene395	1.942e-265	830.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGRP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_3141659_4	1536772.R70723_24040	0.0001088	45.0	COG1846@1|root,COG1846@2|Bacteria,1VDY5@1239|Firmicutes,4HS5G@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_3142381_0	350688.Clos_2048	1.837e-90	305.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,36E9C@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_3142381_1	350688.Clos_2047	1.411e-70	245.0	COG0664@1|root,COG0664@2|Bacteria,1U9VC@1239|Firmicutes,25CK0@186801|Clostridia,36WXM@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21562	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
WZS3_k127_3142381_3	1195236.CTER_3974	3.244e-20	94.0	COG4679@1|root,COG4679@2|Bacteria,1VBSY@1239|Firmicutes,24PZB@186801|Clostridia	186801|Clostridia	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
WZS3_k127_3142381_4	97138.C820_00604	2.853e-11	67.0	COG3620@1|root,COG3620@2|Bacteria,1VH02@1239|Firmicutes,25CZ4@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WZS3_k127_3142381_2	994573.T472_0218970	5.936e-69	238.0	COG0348@1|root,COG0348@2|Bacteria,1V66G@1239|Firmicutes,25IKG@186801|Clostridia,36IJF@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
WZS3_k127_3144500_3	913865.DOT_3576	4.315e-62	214.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,263H1@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
WZS3_k127_3144500_0	634994.GCWU000323_01849	4.744e-113	371.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	speB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
WZS3_k127_3144500_1	1301100.HG529292_gene5165	2.023e-77	267.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,36EC2@31979|Clostridiaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_3144500_2	742740.HMPREF9474_01851	3.333e-72	248.0	COG2199@1|root,COG2203@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,21Z22@1506553|Lachnoclostridium	186801|Clostridia	T	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
WZS3_k127_3178776_1	1117108.PAALTS15_09279	2.554e-46	172.0	COG1957@1|root,COG1957@2|Bacteria,1TSAR@1239|Firmicutes,4HDCS@91061|Bacilli,26S0I@186822|Paenibacillaceae	91061|Bacilli	F	nucleoside	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
WZS3_k127_3178776_0	994573.T472_0201930	2.474e-108	355.0	COG0622@1|root,COG0622@2|Bacteria,1UIW3@1239|Firmicutes,25EZ0@186801|Clostridia,36UTA@31979|Clostridiaceae	186801|Clostridia	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
WZS3_k127_3210893_1	1232449.BAHV02000002_gene230	5.866e-12	69.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,2688N@186813|unclassified Clostridiales	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
WZS3_k127_3210893_0	1423747.BAMJ01000006_gene605	1.366e-82	283.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,3F3WA@33958|Lactobacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
WZS3_k127_3229561_1	1121874.KB892377_gene1339	8.135e-77	261.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,3VP19@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
WZS3_k127_3229561_0	545696.HOLDEFILI_02596	8.419e-129	427.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,3VP34@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Psort location Cytoplasmic, score	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
WZS3_k127_3237193_1	545696.HOLDEFILI_00967	3.196e-275	854.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,3VNYA@526524|Erysipelotrichia	526524|Erysipelotrichia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WZS3_k127_3237193_0	552396.HMPREF0863_00334	3.976e-316	977.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,3VNQQ@526524|Erysipelotrichia	526524|Erysipelotrichia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
WZS3_k127_3237193_2	904293.HMPREF9176_0939	2.95e-12	69.0	COG1195@1|root,COG1195@2|Bacteria	2|Bacteria	L	single-stranded DNA binding	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
WZS3_k127_3272010_4	552396.HMPREF0863_00733	1.448e-50	186.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,3VNW9@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WZS3_k127_3272010_9	545696.HOLDEFILI_03533	1.063e-33	131.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,3VR86@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF965
WZS3_k127_3272010_8	428127.EUBDOL_01331	5.956e-36	141.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,3VQJ4@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
WZS3_k127_3272010_10	1232449.BAHV02000012_gene2377	5.007e-19	91.0	COG3906@1|root,COG3906@2|Bacteria,1VEZY@1239|Firmicutes,252SY@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
WZS3_k127_3272010_1	545696.HOLDEFILI_03536	1.815e-87	301.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,3VNSC@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
WZS3_k127_3272010_2	552396.HMPREF0863_00738	5.729e-86	289.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,3VNZC@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
WZS3_k127_3272010_6	1211819.CALK01000006_gene2569	1.528e-47	175.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,3VQZY@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
WZS3_k127_3272010_11	908340.HMPREF9406_1861	6.304e-17	86.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia	186801|Clostridia	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
WZS3_k127_3272010_5	552396.HMPREF0863_00741	2.577e-48	195.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,3VQ8T@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
WZS3_k127_3272010_3	1211819.CALK01000006_gene2572	2.08e-68	244.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,3VPY3@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
WZS3_k127_3272010_0	545696.HOLDEFILI_03543	3.989e-139	453.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,3VNYV@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location Cytoplasmic, score	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
WZS3_k127_3272010_7	1295642.H839_05654	1.3e-36	142.0	COG1514@1|root,COG1514@2|Bacteria,1VAR5@1239|Firmicutes,4HMP4@91061|Bacilli	91061|Bacilli	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
WZS3_k127_3274075_6	1121472.AQWN01000006_gene1831	1.408e-08	56.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
WZS3_k127_3274075_0	545696.HOLDEFILI_01895	0.0	1457.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,3VNS4@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_alpha,HHH_6,PHP,RNase_T
WZS3_k127_3274075_3	999413.HMPREF1094_03558	4.883e-28	119.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,3VRDA@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	-	-	-	-	-	-	-	-	-	DUF150,DUF150_C
WZS3_k127_3274075_1	999413.HMPREF1094_03557	4.137e-164	532.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,3VNST@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
WZS3_k127_3274075_4	545696.HOLDEFILI_01900	5.035e-27	112.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,3VRKF@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
WZS3_k127_3274075_5	565655.ECBG_00793	4.012e-11	66.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,4HNY7@91061|Bacilli,4B3DJ@81852|Enterococcaceae	91061|Bacilli	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	ylxQ	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
WZS3_k127_3274075_2	545696.HOLDEFILI_01902	4.606e-87	291.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,3VP04@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
WZS3_k127_3285018_2	1410668.JNKC01000003_gene364	8.806e-92	310.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,24JHK@186801|Clostridia,36VPJ@31979|Clostridiaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WZS3_k127_3285018_0	1286171.EAL2_c10220	2.616e-99	334.0	COG2199@1|root,COG2199@2|Bacteria,1UJV0@1239|Firmicutes	1239|Firmicutes	T	GGDEF domain	-	-	2.7.7.65	ko:K18967	-	-	-	-	ko00000,ko01000,ko02000	9.B.34.1.1	-	-	5TM-5TMR_LYT,GGDEF
WZS3_k127_3285018_4	1131462.DCF50_p1459	9.829e-43	171.0	COG2199@1|root,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,24A8B@186801|Clostridia,265FD@186807|Peptococcaceae	186801|Clostridia	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K02488,ko:K18967,ko:K21022	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022	9.B.34.1.1	-	-	GGDEF,PAS_9
WZS3_k127_3285018_3	545696.HOLDEFILI_01770	9.197e-46	168.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,3VRQG@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
WZS3_k127_3285018_5	545696.HOLDEFILI_01771	5.615e-27	114.0	2E4Y1@1|root,32ZRZ@2|Bacteria,1VGPN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3285018_1	33035.JPJF01000007_gene2067	1.803e-95	317.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,3Y032@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4,Fer4_17
WZS3_k127_3290944_0	552396.HMPREF0863_01522	5.069e-174	558.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,3VPCY@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS3_k127_3290944_1	1050201.KB913034_gene342	1.545e-19	90.0	COG0721@1|root,COG0721@2|Bacteria,1VBM2@1239|Firmicutes,3VRD7@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
WZS3_k127_3301045_2	1123308.KB904538_gene17	4.955e-27	111.0	COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4HBJW@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_3301045_1	702450.CUW_2609	1.653e-56	215.0	COG2815@1|root,COG2815@2|Bacteria,1V00M@1239|Firmicutes,3VTNG@526524|Erysipelotrichia	526524|Erysipelotrichia	S	PASTA	-	-	-	-	-	-	-	-	-	-	-	-	PASTA
WZS3_k127_3301045_0	903814.ELI_4480	9.123e-278	870.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,249CQ@186801|Clostridia,25YC1@186806|Eubacteriaceae	186801|Clostridia	P	E1-E2 ATPase	copB	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
WZS3_k127_3301045_4	1408473.JHXO01000013_gene612	1.773e-06	51.0	COG3462@1|root,COG3462@2|Bacteria,4NZBS@976|Bacteroidetes	976|Bacteroidetes	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
WZS3_k127_3301045_3	926561.KB900618_gene311	1.045e-08	59.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_3314915_3	1078085.HMPREF1210_02270	2.997e-07	55.0	COG2746@1|root,COG2746@2|Bacteria,1V2QD@1239|Firmicutes,4HC3S@91061|Bacilli,26DI1@186818|Planococcaceae	91061|Bacilli	V	Aminoglycoside N3'-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
WZS3_k127_3314915_1	158190.SpiGrapes_0348	3.83e-38	147.0	COG0350@1|root,COG0350@2|Bacteria,2J8CJ@203691|Spirochaetes	203691|Spirochaetes	H	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
WZS3_k127_3314915_0	315750.BPUM_2609	8.277e-52	187.0	COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli,1ZFMG@1386|Bacillus	91061|Bacilli	T	GAF domain-containing protein	ytsP	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
WZS3_k127_3314915_2	1123313.ATUT01000007_gene1972	5.617e-29	120.0	COG3859@1|root,COG3859@2|Bacteria,1TTQI@1239|Firmicutes,3VQWG@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Thiamine transporter protein (Thia_YuaJ)	-	-	-	-	-	-	-	-	-	-	-	-	Thia_YuaJ
WZS3_k127_3346947_1	573061.Clocel_0639	6.056e-101	333.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,36ES4@31979|Clostridiaceae	186801|Clostridia	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
WZS3_k127_3346947_5	1031288.AXAA01000010_gene475	7.935e-35	138.0	COG1762@1|root,COG1762@2|Bacteria,1VA2N@1239|Firmicutes,24M3K@186801|Clostridia,36WK6@31979|Clostridiaceae	186801|Clostridia	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.202	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
WZS3_k127_3346947_4	696281.Desru_3141	1.403e-50	190.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia	186801|Clostridia	K	transcriptional regulator DeoR family	-	-	-	ko:K02081,ko:K02530	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
WZS3_k127_3346947_2	484770.UFO1_0941	1.402e-59	218.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4H2ZP@909932|Negativicutes	909932|Negativicutes	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WZS3_k127_3346947_0	994573.T472_0204420	5.292e-162	522.0	COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,36DXV@31979|Clostridiaceae	186801|Clostridia	G	PTS system, fructose subfamily	fruA	-	2.7.1.202	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIC,PTS_IIB
WZS3_k127_3346947_3	698758.AXY_01670	5.204e-57	207.0	COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HCAX@91061|Bacilli	91061|Bacilli	V	ABC transporter (Permease	yclI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS3_k127_3385036_0	83406.HDN1F_21850	4.119e-33	147.0	2DUIR@1|root,33QVE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
WZS3_k127_3417959_1	1304880.JAGB01000002_gene2355	4.343e-26	108.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes	1239|Firmicutes	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
WZS3_k127_3417959_0	1121335.Clst_1032	5.212e-47	183.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,24E6R@186801|Clostridia,3WRN7@541000|Ruminococcaceae	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
WZS3_k127_3417959_3	994573.T472_0214415	4.397e-18	86.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,36MSQ@31979|Clostridiaceae	186801|Clostridia	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WZS3_k127_3417959_2	1345695.CLSA_c21760	9.304e-23	100.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia,36JJV@31979|Clostridiaceae	186801|Clostridia	K	regulatory protein, arsR	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS3_k127_3421014_2	742733.HMPREF9469_03856	2.104e-26	120.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia,21ZP5@1506553|Lachnoclostridium	186801|Clostridia	NTU	Flagellar motor switch protein FliN	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
WZS3_k127_3421014_1	1078085.HMPREF1210_03037	2.514e-89	303.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,4H9UA@91061|Bacilli,26D5G@186818|Planococcaceae	91061|Bacilli	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WZS3_k127_3421014_0	1078085.HMPREF1210_03037	4.339e-96	321.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,4H9UA@91061|Bacilli,26D5G@186818|Planococcaceae	91061|Bacilli	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
WZS3_k127_3421014_3	1514668.JOOA01000002_gene3221	2.039e-16	89.0	28MVF@1|root,2ZB30@2|Bacteria,1UYGK@1239|Firmicutes,25E10@186801|Clostridia,3WGFZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3437251_3	526218.Sterm_0017	2.167e-43	164.0	COG1473@1|root,COG1473@2|Bacteria,378KM@32066|Fusobacteria	32066|Fusobacteria	S	amidohydrolase	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_3437251_0	545696.HOLDEFILI_00409	2.7e-183	589.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,3VNX9@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
WZS3_k127_3437251_1	697281.Mahau_2863	1.044e-73	266.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
WZS3_k127_3437251_2	1033737.CAEV01000040_gene2024	2.755e-72	250.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,36FG9@31979|Clostridiaceae	186801|Clostridia	KT	transcriptional regulatory protein	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_3437251_4	994573.T472_0207800	2.116e-39	153.0	COG0569@1|root,COG0569@2|Bacteria,1V2ZF@1239|Firmicutes,24GNX@186801|Clostridia,36KV4@31979|Clostridiaceae	186801|Clostridia	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
WZS3_k127_3439296_6	658659.HMPREF0983_00653	1.001e-32	130.0	COG1762@1|root,COG1762@2|Bacteria,1VDJE@1239|Firmicutes	1239|Firmicutes	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.194,2.7.1.197	ko:K02798,ko:K02821	ko00051,ko00053,ko01100,ko01120,ko02060,map00051,map00053,map01100,map01120,map02060	M00274,M00283,M00550	R02704,R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5,4.A.7.1	-	-	PTS_EIIA_2
WZS3_k127_3439296_3	658659.HMPREF0983_00656	1.378e-202	639.0	COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,3VP2E@526524|Erysipelotrichia	526524|Erysipelotrichia	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
WZS3_k127_3439296_2	1121874.KB892377_gene1126	2.547e-228	715.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,3VP6W@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Glycosyl hydrolase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
WZS3_k127_3439296_4	411465.PEPMIC_00604	2.494e-119	394.0	COG3177@1|root,COG3177@2|Bacteria,1TV5J@1239|Firmicutes,24CRC@186801|Clostridia,22JCR@1570339|Peptoniphilaceae	186801|Clostridia	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_24,TrmB
WZS3_k127_3439296_1	1034347.CAHJ01000084_gene1339	1.44e-243	759.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,1ZQ3H@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	bglA	GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008422,GO:0015926,GO:0016787,GO:0016798,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901657	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
WZS3_k127_3439296_0	203119.Cthe_1221	0.0	2834.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3WGK9@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyltransferase family 36	ndvB	-	-	-	-	-	-	-	-	-	-	-	DUF3131,Glyco_hydro_36,Glyco_transf_36,Glycoamylase
WZS3_k127_3439296_5	457396.CSBG_02080	8.678e-65	231.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,24BR4@186801|Clostridia,36ESM@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator, RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
WZS3_k127_3441408_0	1211819.CALK01000029_gene2095	1.77e-99	328.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,3VNZH@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
WZS3_k127_3441408_1	1121874.KB892379_gene320	1.148e-28	119.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,3VQ1H@526524|Erysipelotrichia	526524|Erysipelotrichia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WZS3_k127_3447272_2	1120998.AUFC01000001_gene1960	3.081e-37	146.0	COG1237@1|root,COG1237@2|Bacteria,1UWI6@1239|Firmicutes,247K3@186801|Clostridia	186801|Clostridia	S	beta-lactamase superfamily II	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WZS3_k127_3447272_1	933115.GPDM_07005	3.264e-95	319.0	COG2321@1|root,COG2321@2|Bacteria,1TQKF@1239|Firmicutes,4HB7I@91061|Bacilli,26E8G@186818|Planococcaceae	91061|Bacilli	S	Putative neutral zinc metallopeptidase	XK27_03670	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
WZS3_k127_3447272_0	1158612.I580_02990	1.533e-227	713.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli,4AZXW@81852|Enterococcaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	pbg10	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
WZS3_k127_3452786_0	1121947.AUHK01000018_gene511	2.974e-179	570.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,22GX2@1570339|Peptoniphilaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
WZS3_k127_3452786_1	1121874.KB892380_gene1637	7.039e-59	207.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,3VPC8@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WZS3_k127_3462027_9	1232449.BAHV02000001_gene278	9.505e-19	92.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
WZS3_k127_3462027_11	658659.HMPREF0983_02880	2.031e-12	69.0	COG0267@1|root,COG0267@2|Bacteria,1TU0U@1239|Firmicutes,3VRJS@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Ribosomal protein L33	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L33
WZS3_k127_3462027_10	545696.HOLDEFILI_00137	2.905e-15	77.0	COG0690@1|root,COG0690@2|Bacteria,1VKZG@1239|Firmicutes,3VS6P@526524|Erysipelotrichia	526524|Erysipelotrichia	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
WZS3_k127_3462027_4	1121874.KB892380_gene1534	1.022e-86	289.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,3VP0D@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
WZS3_k127_3462027_12	1122917.KB899659_gene5002	9.244e-05	50.0	COG4430@1|root,COG4430@2|Bacteria,1VXQ9@1239|Firmicutes,4HWZU@91061|Bacilli,26YM9@186822|Paenibacillaceae	91061|Bacilli	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3462027_5	679192.HMPREF9013_1177	1.474e-61	215.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,3VQNI@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
WZS3_k127_3462027_2	428127.EUBDOL_00591	3.961e-105	345.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,3VP51@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
WZS3_k127_3462027_1	1347369.CCAD010000083_gene2765	4.404e-205	655.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,4HFIP@91061|Bacilli,1ZD3I@1386|Bacillus	1239|Firmicutes	C	COG2414 Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WZS3_k127_3462027_6	1232449.BAHV02000001_gene272	1.914e-58	207.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,269HE@186813|unclassified Clostridiales	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
WZS3_k127_3462027_8	545696.HOLDEFILI_00116	2.731e-43	162.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,3VQT6@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
WZS3_k127_3462027_7	552396.HMPREF0863_00003	2.484e-46	174.0	COG2813@1|root,COG2813@2|Bacteria,1V1BG@1239|Firmicutes,3VQBU@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Methyltransferase small domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MTS
WZS3_k127_3462027_0	1050201.KB913034_gene171	0.0	1748.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,3VP93@526524|Erysipelotrichia	526524|Erysipelotrichia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
WZS3_k127_3462027_3	552396.HMPREF0863_00001	9.946e-95	312.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,3VNSP@526524|Erysipelotrichia	526524|Erysipelotrichia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WZS3_k127_3471596_1	1196031.ALEG01000013_gene23	5.356e-41	154.0	COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,4HC28@91061|Bacilli,1ZD6T@1386|Bacillus	91061|Bacilli	EGP	Transmembrane secretion effector	ykuC1	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
WZS3_k127_3471596_0	1203611.KB894547_gene2732	4.626e-53	194.0	COG0266@1|root,COG0266@2|Bacteria,4NIT4@976|Bacteroidetes,2FPIR@200643|Bacteroidia	976|Bacteroidetes	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WZS3_k127_3481507_10	485915.Dret_1877	1.519e-26	109.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2M829@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Heavy metal transport detoxification protein	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_3481507_11	572544.Ilyop_1495	2.071e-25	108.0	COG1937@1|root,COG1937@2|Bacteria,37AWC@32066|Fusobacteria	32066|Fusobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WZS3_k127_3481507_5	1301100.HG529422_gene4228	3.953e-53	202.0	COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,249HC@186801|Clostridia,36DCI@31979|Clostridiaceae	186801|Clostridia	P	Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
WZS3_k127_3481507_8	1232449.BAHV02000018_gene1666	1.563e-36	142.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WZS3_k127_3481507_6	1121874.KB892377_gene888	1.562e-40	161.0	COG0760@1|root,COG0760@2|Bacteria,1V2V1@1239|Firmicutes,3VQ9R@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
WZS3_k127_3481507_3	1211819.CALK01000009_gene2860	1.477e-83	287.0	COG0760@1|root,COG0760@2|Bacteria,1V0SC@1239|Firmicutes,3VNQ2@526524|Erysipelotrichia	526524|Erysipelotrichia	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
WZS3_k127_3481507_9	1122985.HMPREF1991_02615	8.038e-27	112.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
WZS3_k127_3481507_2	658659.HMPREF0983_01262	3.367e-114	374.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,3VP09@526524|Erysipelotrichia	526524|Erysipelotrichia	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
WZS3_k127_3481507_7	1235796.C815_01278	1.108e-37	151.0	COG0719@1|root,COG0719@2|Bacteria,1V4N5@1239|Firmicutes	1239|Firmicutes	O	SufB sufD domain protein	sufD	-	-	-	-	-	-	-	-	-	-	-	UPF0051
WZS3_k127_3481507_1	545696.HOLDEFILI_01745	2.911e-171	546.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,3VNSF@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
WZS3_k127_3481507_4	658659.HMPREF0983_01259	4.101e-58	205.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,3VQN7@526524|Erysipelotrichia	526524|Erysipelotrichia	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
WZS3_k127_3481507_0	1211819.CALK01000009_gene2855	3.718e-234	731.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,3VNPN@526524|Erysipelotrichia	526524|Erysipelotrichia	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
WZS3_k127_3481507_12	877415.JNJQ01000002_gene2404	1.154e-20	97.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,3VR5W@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
WZS3_k127_3493259_3	518637.EUBIFOR_00978	3.601e-10	61.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,3VNZH@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
WZS3_k127_3493259_0	428127.EUBDOL_00801	3.323e-199	628.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,3VPAN@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
WZS3_k127_3493259_2	552396.HMPREF0863_00230	1.871e-52	188.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,3VQXR@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score 8.87	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
WZS3_k127_3493259_1	1211819.CALK01000032_gene2976	2.76e-71	247.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,3VNVG@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
WZS3_k127_3493461_4	768486.EHR_08340	6.589e-08	58.0	COG2188@1|root,COG2188@2|Bacteria,1V338@1239|Firmicutes,4HGUM@91061|Bacilli,4B0UU@81852|Enterococcaceae	91061|Bacilli	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_3493461_0	469596.HMPREF9488_00427	6.84e-143	470.0	COG0405@1|root,COG0405@2|Bacteria,1TR9U@1239|Firmicutes,3VPKN@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Gamma-glutamyltranspeptidase	-	-	-	-	-	-	-	-	-	-	-	-	G_glu_transpept
WZS3_k127_3493461_1	1232449.BAHV02000012_gene2231	2.656e-47	175.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,2699Z@186813|unclassified Clostridiales	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WZS3_k127_3493461_2	1414720.CBYM010000012_gene2605	1.013e-46	179.0	COG2059@1|root,COG2059@2|Bacteria,1V3XK@1239|Firmicutes,25CID@186801|Clostridia,36I35@31979|Clostridiaceae	186801|Clostridia	P	overlaps another CDS with the same product name	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WZS3_k127_3493461_3	13035.Dacsa_3508	1.854e-08	57.0	COG4997@1|root,COG4997@2|Bacteria,1G9IR@1117|Cyanobacteria	1117|Cyanobacteria	I	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PRA-PH
WZS3_k127_3506720_8	428126.CLOSPI_01203	5.48e-38	144.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,3VPCI@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location CytoplasmicMembrane, score 10.00	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
WZS3_k127_3506720_2	1396.DJ87_1110	1.674e-123	406.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,4HBAV@91061|Bacilli,1ZC3I@1386|Bacillus	91061|Bacilli	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
WZS3_k127_3506720_7	1121874.KB892377_gene1003	2.513e-51	191.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,3VR0Q@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
WZS3_k127_3506720_4	545696.HOLDEFILI_02991	2.016e-87	294.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,3VNQ3@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
WZS3_k127_3506720_5	545696.HOLDEFILI_02990	4.761e-62	218.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,3VQ8Q@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
WZS3_k127_3506720_3	1211819.CALK01000004_gene2207	4.904e-103	339.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,3VP3R@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS3_k127_3506720_1	545696.HOLDEFILI_02987	1.069e-123	402.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,3VNR6@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
WZS3_k127_3506720_0	552396.HMPREF0863_00810	1.206e-126	413.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,3VP5F@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
WZS3_k127_3506720_6	552396.HMPREF0863_00809	1.398e-61	217.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,3VNQN@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS3_k127_3515935_1	340099.Teth39_2013	3.376e-66	239.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,42FNY@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS3_k127_3515935_0	1219084.AP014508_gene646	5.611e-80	273.0	COG1136@1|root,COG1136@2|Bacteria,2GCNV@200918|Thermotogae	200918|Thermotogae	P	PFAM ABC transporter	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_3518172_5	265729.GS18_0201485	2.716e-16	81.0	COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,1ZGG6@1386|Bacillus	91061|Bacilli	J	Alanine acetyltransferase	yjcK	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WZS3_k127_3518172_4	1027292.HMPREF9372_2235	8.442e-48	178.0	COG2761@1|root,COG2761@2|Bacteria,1TZ1N@1239|Firmicutes,4HEBF@91061|Bacilli,26EM4@186818|Planococcaceae	91061|Bacilli	Q	dithiol-disulfide isomerase involved in polyketide biosynthesis	frnE	-	5.3.4.1	ko:K01829	-	-	-	-	ko00000,ko01000	-	-	-	DSBA
WZS3_k127_3518172_1	1499683.CCFF01000016_gene785	2.192e-153	494.0	COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia,36W96@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
WZS3_k127_3518172_0	699246.HMPREF0868_0182	1.934e-164	529.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WZS3_k127_3518172_3	1499683.CCFF01000016_gene783	2.39e-133	429.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia,36HET@31979|Clostridiaceae	186801|Clostridia	G	Permease	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
WZS3_k127_3518172_2	1499683.CCFF01000016_gene782	9.087e-146	477.0	COG0366@1|root,COG0366@2|Bacteria,1TSEA@1239|Firmicutes,248HJ@186801|Clostridia,36G5W@31979|Clostridiaceae	186801|Clostridia	G	Alpha-amylase domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
WZS3_k127_3532875_2	293826.Amet_2952	3.505e-81	277.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,36EGF@31979|Clostridiaceae	186801|Clostridia	L	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
WZS3_k127_3532875_4	944546.ABED_0839	4.358e-79	285.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_4,PAS_9
WZS3_k127_3532875_6	1397699.JNIS01000001_gene1222	6.868e-67	254.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4084,EAL,GGDEF,PAS_9
WZS3_k127_3532875_13	1480694.DC28_06910	1.354e-19	95.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	grdR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_3532875_14	666686.B1NLA3E_11880	4.404e-18	90.0	COG0716@1|root,COG0716@2|Bacteria,1VFBM@1239|Firmicutes,4HYKX@91061|Bacilli	91061|Bacilli	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3532875_10	158189.SpiBuddy_1136	1.18e-27	116.0	COG3976@1|root,COG3976@2|Bacteria,2JBC4@203691|Spirochaetes	203691|Spirochaetes	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
WZS3_k127_3532875_5	931626.Awo_c05260	2.028e-70	252.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,25V1R@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,PAS_3,Response_reg
WZS3_k127_3532875_11	1280682.AUKA01000002_gene610	5.224e-23	114.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1TRCK@1239|Firmicutes,24A7A@186801|Clostridia,4BX06@830|Butyrivibrio	186801|Clostridia	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,dCache_1
WZS3_k127_3532875_15	1280.SAXN108_2770	7.73e-15	77.0	COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,4HNR2@91061|Bacilli,4GZJA@90964|Staphylococcaceae	91061|Bacilli	S	GCN5-related N-acetyl-transferase	yjdJ	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
WZS3_k127_3532875_9	1499684.CCNP01000018_gene816	1.503e-33	137.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,36IP3@31979|Clostridiaceae	186801|Clostridia	S	IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
WZS3_k127_3532875_3	1347392.CCEZ01000008_gene2229	3.359e-79	275.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,36EYU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
WZS3_k127_3532875_7	1033810.HLPCO_001986	9.038e-57	206.0	COG1121@1|root,COG1121@2|Bacteria,2NPKC@2323|unclassified Bacteria	2|Bacteria	P	ATPases associated with a variety of cellular activities	znuC	-	-	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	M00242,M00244,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
WZS3_k127_3532875_1	1347392.CCEZ01000008_gene2227	5.107e-83	284.0	COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,24875@186801|Clostridia,36EWA@31979|Clostridiaceae	186801|Clostridia	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
WZS3_k127_3532875_16	879309.HMPREF9199_0243	2.423e-13	76.0	COG0735@1|root,COG0735@2|Bacteria,1VF38@1239|Firmicutes,4H5VV@909932|Negativicutes	909932|Negativicutes	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
WZS3_k127_3532875_0	1499689.CCNN01000006_gene552	5.718e-138	464.0	COG0457@1|root,COG2199@1|root,COG2203@1|root,COG0457@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1TQIK@1239|Firmicutes,249Y6@186801|Clostridia,36UV3@31979|Clostridiaceae	186801|Clostridia	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,TPR_12,TPR_8
WZS3_k127_3532875_8	1211819.CALK01000008_gene2652	2.668e-53	192.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,3VP8T@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Respiratory-chain NADH dehydrogenase 24 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
WZS3_k127_3532875_12	877415.JNJQ01000003_gene1751	5.643e-21	96.0	COG3411@1|root,COG3411@2|Bacteria,1V6DT@1239|Firmicutes,3VQN2@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3533018_6	545696.HOLDEFILI_01692	1.663e-05	48.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,3VPIF@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
WZS3_k127_3533018_0	555079.Toce_1989	1.686e-119	400.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia,42F2V@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
WZS3_k127_3533018_2	293826.Amet_2172	1.709e-90	307.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1VB8N@1239|Firmicutes,25EJ3@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
WZS3_k127_3533018_5	1211814.CAPG01000074_gene3428	1.072e-27	118.0	COG5646@1|root,COG5646@2|Bacteria,1TRQ8@1239|Firmicutes,4IPYN@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WZS3_k127_3533018_1	767817.Desgi_3532	4.943e-110	386.0	COG2199@1|root,COG2200@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2202@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,267EP@186807|Peptococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Peripla_BP_3
WZS3_k127_3533018_3	290402.Cbei_4163	1.851e-44	185.0	COG2206@1|root,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia,36USB@31979|Clostridiaceae	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9
WZS3_k127_3533018_4	720554.Clocl_2908	1.042e-34	139.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,3WK3U@541000|Ruminococcaceae	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WZS3_k127_3534312_1	1121874.KB892378_gene655	2.206e-84	288.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,3VRAG@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WZS3_k127_3534312_3	1223521.BBJX01000019_gene613	4.086e-08	60.0	COG0716@1|root,COG0716@2|Bacteria,1NANK@1224|Proteobacteria,2VW78@28216|Betaproteobacteria,4AHHR@80864|Comamonadaceae	28216|Betaproteobacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
WZS3_k127_3534312_2	552396.HMPREF0863_00608	4.313e-55	199.0	COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,3VUPW@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WZS3_k127_3534312_0	999413.HMPREF1094_01632	9.499e-101	332.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,3VP43@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
WZS3_k127_355882_6	717605.Theco_2704	1.657e-05	55.0	COG4758@1|root,COG4758@2|Bacteria,1VG3U@1239|Firmicutes,4HMA7@91061|Bacilli,26SC0@186822|Paenibacillaceae	91061|Bacilli	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	ko:K11622	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	DUF2154
WZS3_k127_355882_3	518637.EUBIFOR_01770	2.472e-27	121.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,3VQEU@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
WZS3_k127_355882_2	469596.HMPREF9488_00463	8.062e-40	157.0	COG1335@1|root,COG1335@2|Bacteria,1V8NT@1239|Firmicutes	1239|Firmicutes	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
WZS3_k127_355882_5	1234679.BN424_3530	5.265e-06	57.0	COG3631@1|root,COG3631@2|Bacteria,1VC7Y@1239|Firmicutes,4HMVN@91061|Bacilli	91061|Bacilli	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
WZS3_k127_355882_0	1232449.BAHV02000016_gene1892	0.0	1314.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,2687P@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
WZS3_k127_355882_1	1232449.BAHV02000020_gene1322	1.057e-71	248.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,267Q9@186813|unclassified Clostridiales	186801|Clostridia	S	Radical_SAM C-terminal domain	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
WZS3_k127_3561693_2	1232449.BAHV02000008_gene716	8.628e-62	224.0	COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,247S9@186801|Clostridia,26B3G@186813|unclassified Clostridiales	186801|Clostridia	H	Bacterial lipoate protein ligase C-terminus	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,Lip_prot_lig_C
WZS3_k127_3561693_5	545696.HOLDEFILI_04125	6.566e-20	92.0	COG0526@1|root,COG0526@2|Bacteria,1UM1J@1239|Firmicutes,3VRMY@526524|Erysipelotrichia	526524|Erysipelotrichia	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_3
WZS3_k127_3561693_4	1499689.CCNN01000007_gene959	1.716e-36	146.0	COG0170@1|root,COG0170@2|Bacteria,1UJ3I@1239|Firmicutes,24I8C@186801|Clostridia,36RKH@31979|Clostridiaceae	186801|Clostridia	I	dolichyl monophosphate biosynthetic process	-	-	2.7.1.182	ko:K18678	-	-	R10659	RC00002,RC00017	ko00000,ko01000	-	-	-	-
WZS3_k127_3561693_3	428127.EUBDOL_01197	1.83e-55	203.0	COG0500@1|root,COG2226@2|Bacteria,1V1WE@1239|Firmicutes,3VQI7@526524|Erysipelotrichia	526524|Erysipelotrichia	Q	Methyltransferase domain	rrmA	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_31
WZS3_k127_3561693_0	649761.HMPREF0973_02124	4.481e-122	395.0	COG0708@1|root,COG0708@2|Bacteria,4NEY3@976|Bacteroidetes,2FNRH@200643|Bacteroidia	976|Bacteroidetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
WZS3_k127_3561693_1	1071073.KI530553_gene3802	6.576e-88	304.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HCSB@91061|Bacilli,1ZMEP@1386|Bacillus	91061|Bacilli	J	RNA cap guanine-N2 methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
WZS3_k127_3582573_2	552396.HMPREF0863_01172	0.0002372	48.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,3VPN7@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
WZS3_k127_3582573_0	552396.HMPREF0863_01173	5.575e-67	236.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,3VQK7@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
WZS3_k127_3587123_2	1211819.CALK01000051_gene1539	2.878e-137	455.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,3VNZW@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
WZS3_k127_3587123_5	1399115.U719_00130	1.227e-62	220.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli,3WE2K@539002|Bacillales incertae sedis	91061|Bacilli	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
WZS3_k127_3587123_3	545696.HOLDEFILI_01098	6.161e-76	259.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,3VQC9@526524|Erysipelotrichia	526524|Erysipelotrichia	S	R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
WZS3_k127_3587123_4	650150.ERH_1702	2.248e-67	239.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,3VPDR@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Membrane protein insertase, YidC Oxa1 family	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
WZS3_k127_3587123_6	1232446.BAIE02000060_gene3203	2.2e-28	118.0	COG0594@1|root,COG0594@2|Bacteria	2|Bacteria	J	ribonuclease P activity	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
WZS3_k127_3587123_7	650150.ERH_1704	4.315e-17	81.0	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,3VS2T@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
WZS3_k127_3587123_0	545696.HOLDEFILI_01088	1.137e-172	553.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,3VNTZ@526524|Erysipelotrichia	526524|Erysipelotrichia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
WZS3_k127_3587123_1	1211819.CALK01000050_gene1517	4.143e-172	546.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,3VPM6@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
WZS3_k127_3592362_1	1120998.AUFC01000016_gene74	6.363e-41	153.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WDS9@538999|Clostridiales incertae sedis	186801|Clostridia	K	COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_3592362_0	523794.Lebu_2012	4.268e-68	248.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HAMP,HATPase_c,HisKA,PAS_8,PAS_9,Response_reg
WZS3_k127_3606405_8	1121874.KB892379_gene44	6.71e-76	265.0	COG0642@1|root,COG0642@2|Bacteria,1UJ2Z@1239|Firmicutes,3VNSX@526524|Erysipelotrichia	526524|Erysipelotrichia	T	sensor histidine kinase	-	-	2.7.13.3	ko:K07650	ko02020,map02020	M00448	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_3606405_3	1232449.BAHV02000018_gene1605	7.066e-113	366.0	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,24DTS@186801|Clostridia	186801|Clostridia	K	response regulator receiver	cssR	-	-	ko:K07770	ko02020,map02020	M00448	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_3606405_0	545696.HOLDEFILI_03808	1.413e-157	508.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,3VNWX@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WZS3_k127_3606405_2	1211819.CALK01000017_gene521	7.153e-124	411.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,3VPRQ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
WZS3_k127_3606405_4	545696.HOLDEFILI_03810	2.934e-107	363.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,3VPNZ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
WZS3_k127_3606405_6	545696.HOLDEFILI_03813	2.07e-104	351.0	COG1916@1|root,COG1916@2|Bacteria,1TSWJ@1239|Firmicutes,3VSFN@526524|Erysipelotrichia	526524|Erysipelotrichia	S	TraB family	-	-	-	-	-	-	-	-	-	-	-	-	TraB
WZS3_k127_3606405_7	1540257.JQMW01000013_gene1295	1.031e-93	312.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,36EAR@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_3606405_1	1304880.JAGB01000002_gene1654	1.833e-137	447.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
WZS3_k127_3606405_5	545696.HOLDEFILI_03817	7.417e-105	349.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,3VNVE@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
WZS3_k127_3606405_9	469596.HMPREF9488_02123	1.837e-59	210.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,3VPVQ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_3615352_1	1201292.DR75_226	4.276e-26	110.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli,4B02D@81852|Enterococcaceae	91061|Bacilli	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
WZS3_k127_3615352_2	552396.HMPREF0863_01066	5.461e-22	102.0	COG3935@1|root,COG3935@2|Bacteria,1TTUD@1239|Firmicutes,3VR57@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DnaD domain protein	-	-	-	ko:K02086	-	-	-	-	ko00000	-	-	-	DnaB_2
WZS3_k127_3615352_3	545696.HOLDEFILI_03691	3.419e-14	79.0	2ESA9@1|root,33JUZ@2|Bacteria,1VQDP@1239|Firmicutes,3VS9N@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3615352_0	1211819.CALK01000004_gene2148	2.507e-52	192.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,3VQCF@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_3629387_0	994573.T472_0218945	2.155e-137	442.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,36DHF@31979|Clostridiaceae	186801|Clostridia	C	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WZS3_k127_3629387_2	1211819.CALK01000047_gene1819	9.223e-52	184.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,3VQTM@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
WZS3_k127_3629387_1	679192.HMPREF9013_0928	6.728e-91	304.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,3VPRB@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
WZS3_k127_3630845_3	1232449.BAHV02000010_gene3103	1.866e-76	263.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,268S3@186813|unclassified Clostridiales	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WZS3_k127_3630845_6	1123313.ATUT01000015_gene658	1.007e-09	68.0	COG1589@1|root,COG1589@2|Bacteria,1V0PZ@1239|Firmicutes,3VR1K@526524|Erysipelotrichia	526524|Erysipelotrichia	M	POTRA domain, FtsQ-type	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_1
WZS3_k127_3630845_5	1211819.CALK01000005_gene2449	6.421e-53	188.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,3VR17@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WZS3_k127_3630845_0	1211819.CALK01000005_gene2450	1.858e-202	643.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,3VNPV@526524|Erysipelotrichia	526524|Erysipelotrichia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
WZS3_k127_3630845_1	1232449.BAHV02000010_gene3111	1.747e-181	589.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,267P4@186813|unclassified Clostridiales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WZS3_k127_3630845_4	1211819.CALK01000005_gene2455	8.242e-65	229.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,3VNU2@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
WZS3_k127_3630845_2	1123313.ATUT01000001_gene985	1.778e-81	285.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,3VPSC@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score	gltA	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Pyr_redox_2
WZS3_k127_3675793_0	1235835.C814_03260	5.221e-60	217.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,24AGV@186801|Clostridia,3WIQE@541000|Ruminococcaceae	186801|Clostridia	N	flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
WZS3_k127_3675793_1	877411.JMMA01000002_gene2975	4.442e-46	175.0	COG4786@1|root,COG4786@2|Bacteria,1TT5Z@1239|Firmicutes,248M9@186801|Clostridia,3WJ82@541000|Ruminococcaceae	186801|Clostridia	N	Flagellar basal body rod protein	flgG	-	-	ko:K02390,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WZS3_k127_3675793_2	658086.HMPREF0994_00552	2.65e-21	97.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia,27JJZ@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WZS3_k127_3680102_2	632245.CLP_0165	3.38e-88	295.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
WZS3_k127_3680102_0	411902.CLOBOL_00410	7.16e-123	401.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,21YKJ@1506553|Lachnoclostridium	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
WZS3_k127_3680102_1	1499967.BAYZ01000076_gene784	8.393e-103	339.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WZS3_k127_3707515_2	1541960.KQ78_00623	2.936e-54	195.0	COG1879@1|root,COG1879@2|Bacteria,3WUR4@544448|Tenericutes	544448|Tenericutes	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
WZS3_k127_3707515_1	1209989.TepiRe1_0808	3.168e-101	339.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,42I0U@68295|Thermoanaerobacterales	186801|Clostridia	G	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	mglB2	-	-	ko:K10540,ko:K17213	ko02010,ko02030,map02010,map02030	M00214,M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.3	-	-	Peripla_BP_4
WZS3_k127_3707515_0	1123009.AUID01000015_gene2006	4.696e-205	649.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,26882@186813|unclassified Clostridiales	186801|Clostridia	G	Part of the ABC transporter complex MglABC involved in galactose methyl galactoside import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
WZS3_k127_3719439_0	1211819.CALK01000022_gene1636	1.307e-177	577.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,3VP8D@526524|Erysipelotrichia	526524|Erysipelotrichia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
WZS3_k127_3719439_1	545696.HOLDEFILI_00405	3.387e-54	194.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,3VQI2@526524|Erysipelotrichia	526524|Erysipelotrichia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
WZS3_k127_3719439_3	1449335.JQLG01000005_gene2420	2.121e-22	100.0	COG1396@1|root,COG1396@2|Bacteria,1VMY1@1239|Firmicutes,4HRA4@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
WZS3_k127_3719439_2	650150.ERH_0112	1.466e-35	144.0	COG4907@1|root,COG4907@2|Bacteria,1TR4I@1239|Firmicutes,3VPT6@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
WZS3_k127_3727448_1	1123075.AUDP01000062_gene1779	3.926e-128	413.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3WGNI@541000|Ruminococcaceae	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
WZS3_k127_3727448_2	428125.CLOLEP_00762	2.331e-71	245.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24EHP@186801|Clostridia,3WRUR@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
WZS3_k127_3727448_0	1123313.ATUT01000005_gene213	8.066e-225	706.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,3VNRN@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
WZS3_k127_3730579_0	552396.HMPREF0863_00733	4.284e-203	648.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,3VNW9@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
WZS3_k127_3750263_0	1301100.HG529409_gene190	1.086e-72	250.0	COG2391@1|root,COG2391@2|Bacteria,1TS7S@1239|Firmicutes,24CIP@186801|Clostridia,36I97@31979|Clostridiaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
WZS3_k127_3750263_1	1163671.JAGI01000002_gene2292	6.652e-39	153.0	COG0583@1|root,COG0583@2|Bacteria,1V3AK@1239|Firmicutes,25C6T@186801|Clostridia,36WQR@31979|Clostridiaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
WZS3_k127_3756147_1	1454202.PPBDW_130439___1	3.726e-26	112.0	COG1661@1|root,COG1661@2|Bacteria,1RIME@1224|Proteobacteria,1S71M@1236|Gammaproteobacteria,1XXZ3@135623|Vibrionales	135623|Vibrionales	S	DNA-binding protein with PD1-like DNA-binding motif	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
WZS3_k127_3756147_0	555088.DealDRAFT_0206	6.262e-62	223.0	COG1277@1|root,COG1277@2|Bacteria,1V2P1@1239|Firmicutes,24BRH@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
WZS3_k127_3756147_2	555088.DealDRAFT_0207	1.276e-14	76.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,SRP54
WZS3_k127_376103_0	1235835.C814_03251	1.379e-164	529.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,3WHXC@541000|Ruminococcaceae	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
WZS3_k127_376103_1	350688.Clos_1510	5.809e-22	101.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia,36EEW@31979|Clostridiaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS3_k127_3771520_3	1298920.KI911353_gene1962	4.734e-07	52.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,21YAI@1506553|Lachnoclostridium	186801|Clostridia	C	Psort location Cytoplasmic, score	bdhA	GO:0003674,GO:0003824,GO:0004022,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	-	ko:K00100,ko:K19955	ko00650,ko01120,map00650,map01120	-	R03544,R03545	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
WZS3_k127_3771520_2	1122917.KB899659_gene4876	2.727e-45	166.0	COG5646@1|root,COG5646@2|Bacteria,1V6QT@1239|Firmicutes,4HIUI@91061|Bacilli,26XR5@186822|Paenibacillaceae	91061|Bacilli	S	Iron chaperone	frataxin	-	-	ko:K05937	-	-	-	-	ko00000	-	-	-	DUF1801
WZS3_k127_3771520_0	1294142.CINTURNW_2531	3.397e-55	196.0	COG0537@1|root,COG0537@2|Bacteria,1V7FG@1239|Firmicutes,24H6W@186801|Clostridia,36FR5@31979|Clostridiaceae	186801|Clostridia	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WZS3_k127_3771520_1	883114.HMPREF9709_00943	8.271e-47	174.0	COG1670@1|root,COG1670@2|Bacteria,1V1G4@1239|Firmicutes,24G4Y@186801|Clostridia,22HEH@1570339|Peptoniphilaceae	186801|Clostridia	J	Acetyltransferase, GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_3776135_1	1121324.CLIT_2c00270	4.603e-76	263.0	COG2207@1|root,COG2207@2|Bacteria,1TQDS@1239|Firmicutes,24907@186801|Clostridia	186801|Clostridia	K	AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WZS3_k127_3776135_0	411467.BACCAP_04252	9.149e-136	439.0	COG3250@1|root,COG3250@2|Bacteria,1TSMY@1239|Firmicutes,24B54@186801|Clostridia,267NZ@186813|unclassified Clostridiales	186801|Clostridia	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
WZS3_k127_3797675_0	545696.HOLDEFILI_03260	1.714e-246	783.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,3VNSJ@526524|Erysipelotrichia	526524|Erysipelotrichia	F	bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain glutamine amidotransferase domain) K01952	-	-	-	-	-	-	-	-	-	-	-	-	AIRS_C,GATase_5
WZS3_k127_3797675_1	866775.HMPREF9243_0933	1.028e-46	177.0	COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli,27DUX@186827|Aerococcaceae	91061|Bacilli	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp
WZS3_k127_3803600_1	457421.CBFG_03035	3.484e-89	300.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,268XI@186813|unclassified Clostridiales	186801|Clostridia	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WZS3_k127_3803600_0	908340.HMPREF9406_4200	6.867e-91	310.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,36F0A@31979|Clostridiaceae	186801|Clostridia	GKT	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
WZS3_k127_3811014_0	545696.HOLDEFILI_01282	5.209e-285	898.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,3VNVX@526524|Erysipelotrichia	526524|Erysipelotrichia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WZS3_k127_3822178_5	760011.Spico_1396	5.181e-24	102.0	COG4720@1|root,COG4720@2|Bacteria,2J802@203691|Spirochaetes	203691|Spirochaetes	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16924	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.29	-	-	ECF-ribofla_trS
WZS3_k127_3822178_0	760011.Spico_1395	1.95e-205	653.0	COG1122@1|root,COG1122@2|Bacteria,2J5SA@203691|Spirochaetes	203691|Spirochaetes	P	ABC transporter	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,CbiQ,DUF3744
WZS3_k127_3822178_2	760011.Spico_1394	1.411e-99	332.0	COG0619@1|root,COG0619@2|Bacteria,2J6H7@203691|Spirochaetes	203691|Spirochaetes	P	cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
WZS3_k127_3822178_1	760011.Spico_1393	6.568e-106	358.0	COG0624@1|root,COG0624@2|Bacteria,2J8J5@203691|Spirochaetes	203691|Spirochaetes	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Peptidase_M20
WZS3_k127_3822178_4	1449050.JNLE01000003_gene3056	2.983e-89	302.0	COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,24D3T@186801|Clostridia,36F3F@31979|Clostridiaceae	186801|Clostridia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
WZS3_k127_3822178_3	1095737.HMPREF1110_1288	5.247e-96	321.0	COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,4HAW6@91061|Bacilli,2TNZ4@28037|Streptococcus mitis	91061|Bacilli	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	XK27_10120	-	-	-	-	-	-	-	-	-	-	-	SAM_adeno_trans
WZS3_k127_3822178_6	1122915.AUGY01000191_gene5211	4.765e-08	57.0	COG4912@1|root,COG4912@2|Bacteria,1TSAW@1239|Firmicutes,4HABR@91061|Bacilli,26S5C@186822|Paenibacillaceae	91061|Bacilli	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WZS3_k127_3846091_5	2754.EH55_05710	7.161e-19	87.0	COG1167@1|root,COG1167@2|Bacteria,3T9R5@508458|Synergistetes	508458|Synergistetes	EK	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WZS3_k127_3846091_1	1211819.CALK01000047_gene1803	3.887e-226	704.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,3VNVP@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
WZS3_k127_3846091_0	1121874.KB892378_gene490	0.0	1122.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,3VP6G@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WZS3_k127_3846091_3	1232449.BAHV02000010_gene2432	9.188e-84	279.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,268CC@186813|unclassified Clostridiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
WZS3_k127_3846091_4	1232449.BAHV02000010_gene2431	2.028e-73	248.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,268YZ@186813|unclassified Clostridiales	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
WZS3_k127_3846091_2	428127.EUBDOL_00586	1.689e-198	647.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,3VNSP@526524|Erysipelotrichia	526524|Erysipelotrichia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WZS3_k127_38514_1	536227.CcarbDRAFT_4281	3.467e-40	157.0	COG0122@1|root,COG0122@2|Bacteria,1V2ZM@1239|Firmicutes,248KP@186801|Clostridia,36IYP@31979|Clostridiaceae	186801|Clostridia	L	HhH-GPD superfamily base excision DNA repair protein	-	-	2.1.1.63,3.2.2.21	ko:K00567,ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
WZS3_k127_38514_0	469596.HMPREF9488_01875	1.644e-40	154.0	COG0143@1|root,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,3VNSG@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
WZS3_k127_3899185_7	552396.HMPREF0863_02210	1.773e-17	82.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,3VPF1@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Transketolase, pyridine binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
WZS3_k127_3899185_3	666686.B1NLA3E_12465	7.995e-55	205.0	arCOG06802@1|root,2ZBBG@2|Bacteria,1V17K@1239|Firmicutes,4HTUX@91061|Bacilli,1ZG57@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3899185_8	398512.JQKC01000044_gene1248	4.616e-17	83.0	2C4HU@1|root,2ZT28@2|Bacteria,1V5DD@1239|Firmicutes,24TDG@186801|Clostridia,3WM9C@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
WZS3_k127_3899185_4	573061.Clocel_3238	4.241e-33	131.0	2C4HU@1|root,2ZT28@2|Bacteria,1V5DD@1239|Firmicutes,24TDG@186801|Clostridia,36MFV@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
WZS3_k127_3899185_6	138119.DSY1024	3.138e-20	96.0	COG2062@1|root,COG2062@2|Bacteria,1VGUB@1239|Firmicutes,24SGN@186801|Clostridia	186801|Clostridia	T	Histidine phosphatase superfamily (branch 1)	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
WZS3_k127_3899185_9	525898.Sdel_1214	8.935e-07	59.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	sixA-2	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,His_Phos_1
WZS3_k127_3899185_2	445974.CLORAM_03154	7.697e-110	364.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,3VPPS@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WZS3_k127_3899185_5	1158607.UAU_00443	3.336e-24	108.0	COG4702@1|root,COG4702@2|Bacteria,1VBQP@1239|Firmicutes,4HKW7@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0303 family	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
WZS3_k127_3899185_0	469596.HMPREF9488_02477	2.912e-134	435.0	COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes,3VPHV@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WZS3_k127_3899185_1	1235798.C817_04824	1.136e-124	413.0	COG1823@1|root,COG1823@2|Bacteria,1UPUK@1239|Firmicutes,24H65@186801|Clostridia	186801|Clostridia	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	ko:K06956	-	-	-	-	ko00000	-	-	-	SDF
WZS3_k127_39132_1	1232446.BAIE02000027_gene2585	1.056e-244	760.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
WZS3_k127_39132_0	1211819.CALK01000023_gene1703	1.83e-312	968.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,3VNVI@526524|Erysipelotrichia	526524|Erysipelotrichia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WZS3_k127_3915927_0	931626.Awo_c00900	9.416e-146	471.0	COG2211@1|root,COG2211@2|Bacteria,1UJS2@1239|Firmicutes,25F8F@186801|Clostridia,25X2H@186806|Eubacteriaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS3_k127_3915927_1	350688.Clos_0643	9.857e-110	367.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,36ECU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WZS3_k127_3915927_3	1347087.CBYO010000022_gene3437	1.568e-38	148.0	2CHCP@1|root,32S5R@2|Bacteria,1V3HI@1239|Firmicutes,4HGYA@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WZS3_k127_3915927_4	1321784.HMPREF1987_01798	8.709e-36	139.0	COG1695@1|root,COG1695@2|Bacteria,1V9XX@1239|Firmicutes,24RE5@186801|Clostridia,25TXF@186804|Peptostreptococcaceae	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WZS3_k127_3915927_2	350688.Clos_2225	4.057e-49	180.0	2DN4N@1|root,32UIA@2|Bacteria,1VA2T@1239|Firmicutes,24JJM@186801|Clostridia,36KM0@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2812)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
WZS3_k127_3915927_5	1123359.AUIQ01000073_gene506	2.367e-27	113.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,4HBFK@91061|Bacilli,4B0CH@81852|Enterococcaceae	91061|Bacilli	S	ABC transporter	yjcA	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran,ABC_tran_Xtn
WZS3_k127_3925594_1	1507.HMPREF0262_01633	8.854e-74	257.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,36FIQ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WZS3_k127_3925594_2	511051.CSE_14170	4.926e-71	250.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	rihB	GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042454,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045437,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0050263,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	3.2.2.1,3.2.2.8	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	-	R01245,R01273,R01677,R01770,R02137,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	iECH74115_1262.ECH74115_3298,iECSP_1301.ECSP_3040,iECs_1301.ECs3054,iSFV_1184.SFV_2237,iSF_1195.SF2247,iSFxv_1172.SFxv_2480,iS_1188.S2376,iZ_1308.Z3419	IU_nuc_hydro
WZS3_k127_3925594_0	1487921.DP68_05530	4.623e-118	387.0	COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,24A4D@186801|Clostridia,36FHB@31979|Clostridiaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 7.50	rihA	-	-	ko:K01250	-	-	-	-	ko00000,ko01000	-	-	-	IU_nuc_hydro
WZS3_k127_3952884_0	1158609.I586_00634	4.044e-92	310.0	COG1307@1|root,COG1307@2|Bacteria,1TYCV@1239|Firmicutes,4HD8F@91061|Bacilli,4AZQW@81852|Enterococcaceae	91061|Bacilli	K	Uncharacterised protein, DegV family COG1307	degV	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_3952884_1	641524.ADICYQ_5314	1.379e-41	159.0	COG3832@1|root,COG3832@2|Bacteria,4NQ4A@976|Bacteroidetes	976|Bacteroidetes	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
WZS3_k127_3952884_4	658655.HMPREF0988_01410	6.332e-31	130.0	arCOG13338@1|root,2Z9XC@2|Bacteria,1UPRH@1239|Firmicutes,25HMN@186801|Clostridia,27P6T@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF5058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5058
WZS3_k127_3952884_2	658086.HMPREF0994_06252	2.993e-38	151.0	28N4D@1|root,2ZB9V@2|Bacteria,1UPRR@1239|Firmicutes,24MJV@186801|Clostridia,27PAI@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3952884_3	1150399.AQYK01000001_gene1424	4.122e-37	147.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria,4FMF9@85023|Microbacteriaceae	201174|Actinobacteria	E	Peptidase family M20/M25/M40	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS3_k127_3953523_1	655811.HMPREF0078_0190	5.628e-71	245.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,22I4F@1570339|Peptoniphilaceae	186801|Clostridia	P	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WZS3_k127_3953523_4	1158602.I590_03584	9.235e-25	109.0	COG1846@1|root,COG1846@2|Bacteria,1TVJ8@1239|Firmicutes,4HJ00@91061|Bacilli,4B38R@81852|Enterococcaceae	91061|Bacilli	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	MarR
WZS3_k127_3953523_0	1230342.CTM_18934	1.85e-201	636.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,36DJD@31979|Clostridiaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_3953523_3	1294142.CINTURNW_3319	2.22e-57	207.0	COG2364@1|root,COG2364@2|Bacteria,1US09@1239|Firmicutes,24HRG@186801|Clostridia,36K5Q@31979|Clostridiaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3953523_2	1540257.JQMW01000009_gene2836	6.225e-69	250.0	COG2199@1|root,COG2199@2|Bacteria,1V5WD@1239|Firmicutes,249N6@186801|Clostridia,36HFR@31979|Clostridiaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HisKA_7TM,PAS_9
WZS3_k127_3965671_1	1507.HMPREF0262_02181	1.915e-80	274.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,36E6C@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WZS3_k127_3965671_0	1410668.JNKC01000003_gene482	3.282e-172	547.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,36DF0@31979|Clostridiaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
WZS3_k127_3966151_2	545696.HOLDEFILI_00944	6.708e-32	126.0	2CENR@1|root,30Z2M@2|Bacteria,1V520@1239|Firmicutes,3VURN@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_3966151_0	545696.HOLDEFILI_00954	2.022e-215	682.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,3VNVC@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Formyltetrahydrofolate synthetase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
WZS3_k127_3966151_1	1232449.BAHV02000002_gene50	1.768e-78	267.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,268S8@186813|unclassified Clostridiales	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
WZS3_k127_3966151_3	1211819.CALK01000049_gene1509	9.795e-08	59.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,3VPGE@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WZS3_k127_3966410_2	1232449.BAHV02000012_gene2209	6.352e-54	192.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,267UV@186813|unclassified Clostridiales	186801|Clostridia	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
WZS3_k127_3966410_4	877415.JNJQ01000003_gene1721	7.2e-17	84.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,3VRPS@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
WZS3_k127_3966410_1	545696.HOLDEFILI_03578	3.863e-81	281.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,3VP8N@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
WZS3_k127_3966410_0	545696.HOLDEFILI_03576	0.0	1075.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,3VP2U@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
WZS3_k127_3966410_3	1211844.CBLM010000040_gene2872	1.654e-47	175.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,3VQI5@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Antioxidant, AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
WZS3_k127_3966410_5	1229520.ADIAL_0473	2.795e-05	50.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli,27FPK@186828|Carnobacteriaceae	91061|Bacilli	G	Alpha-amylase domain	-	-	3.2.1.10,3.2.1.20,3.2.1.70	ko:K01182,ko:K01187,ko:K01215	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01718,R01791,R06087,R06088,R06199	RC00028,RC00049,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
WZS3_k127_3974222_0	996306.SSUR61_1860	7.714e-170	546.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli,1WSD8@1307|Streptococcus suis	91061|Bacilli	S	Permease family	XK27_07275	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
WZS3_k127_397517_1	545696.HOLDEFILI_02623	1.063e-12	71.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,3VP0B@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Peptidase, U32 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32,Peptidase_U32_C
WZS3_k127_397517_0	1123263.AUKY01000006_gene2255	1.791e-50	188.0	COG0566@1|root,COG0566@2|Bacteria,1V1NM@1239|Firmicutes,3VQ8P@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase,SpoU_sub_bind
WZS3_k127_397681_0	1232449.BAHV02000018_gene1684	7.868e-152	497.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,267JB@186813|unclassified Clostridiales	186801|Clostridia	NU	Type II/IV secretion system protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WZS3_k127_397681_1	1286171.EAL2_808p06220	2.861e-136	441.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
WZS3_k127_3998384_1	1232449.BAHV02000010_gene2756	7.483e-95	332.0	COG4907@1|root,COG4907@2|Bacteria,1TR4I@1239|Firmicutes,2496W@186801|Clostridia,26A41@186813|unclassified Clostridiales	186801|Clostridia	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
WZS3_k127_3998384_2	650150.ERH_0111	1.43e-72	248.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,3VQJK@526524|Erysipelotrichia	526524|Erysipelotrichia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
WZS3_k127_3998384_4	500635.MITSMUL_04025	2.755e-22	99.0	COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,4H5H4@909932|Negativicutes	909932|Negativicutes	G	PTS system, Lactose/Cellobiose specific IIB subunit	chbB	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
WZS3_k127_3998384_3	642492.Clole_3244	1.429e-38	157.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,24A3Q@186801|Clostridia	186801|Clostridia	P	ABC-type phosphate phosphonate transport system periplasmic component	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
WZS3_k127_3998384_0	650150.ERH_0424	1.372e-137	453.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,3VQ00@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
WZS3_k127_4033496_3	1033810.HLPCO_000784	7.694e-12	72.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K15770,ko:K17318	ko02010,map02010	M00491,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2,3.A.1.1.29,3.A.1.1.9	-	-	DUF3502
WZS3_k127_4033496_1	1227352.C173_06962	8.944e-125	428.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,26QWH@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_4,PAS_9,Peripla_BP_3,SBP_bac_3
WZS3_k127_4033496_0	1211819.CALK01000018_gene683	1.668e-256	808.0	COG0366@1|root,COG0366@2|Bacteria,1TSC7@1239|Firmicutes,3VPER@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
WZS3_k127_4033496_2	180332.JTGN01000023_gene1652	3.351e-93	314.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
WZS3_k127_4035895_2	1123263.AUKY01000064_gene1892	5.449e-124	403.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,3VPK4@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
WZS3_k127_4035895_4	999413.HMPREF1094_04038	5.035e-55	206.0	COG0392@1|root,COG0392@2|Bacteria,1TR9T@1239|Firmicutes,3VPDC@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
WZS3_k127_4035895_6	768704.Desmer_1495	2.39e-22	105.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,2626V@186807|Peptococcaceae	186801|Clostridia	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
WZS3_k127_4035895_1	545696.HOLDEFILI_03227	1.417e-160	526.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,3VPBV@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Fibronectin-binding protein A domain protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
WZS3_k127_4035895_3	552396.HMPREF0863_01202	2.154e-81	274.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,3VPP7@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
WZS3_k127_4035895_0	1232449.BAHV02000017_gene1455	8.903e-174	572.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,268ES@186813|unclassified Clostridiales	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
WZS3_k127_4035895_5	545696.HOLDEFILI_01752	1.469e-28	123.0	COG0144@1|root,COG0144@2|Bacteria,1TP3N@1239|Firmicutes,3VNW5@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
WZS3_k127_403861_0	545696.HOLDEFILI_03012	1.429e-37	148.0	COG4193@1|root,COG4193@2|Bacteria,1UT0U@1239|Firmicutes,3VPXP@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glucosaminidase
WZS3_k127_403861_1	706433.HMPREF9430_01772	5.25e-11	73.0	COG4193@1|root,COG5263@1|root,COG4193@2|Bacteria,COG5263@2|Bacteria,1UT0U@1239|Firmicutes,3VPXP@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glucosaminidase
WZS3_k127_4043198_1	865861.AZSU01000005_gene915	7.298e-93	316.0	COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,24CKX@186801|Clostridia,36RB5@31979|Clostridiaceae	186801|Clostridia	S	PAS domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	DUF1858,DUF2249,DUF438,Hemerythrin,PAS_10
WZS3_k127_4043198_2	1410658.JHWI01000005_gene908	1.707e-51	188.0	COG0350@1|root,COG0693@1|root,COG0350@2|Bacteria,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,3VUPK@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
WZS3_k127_4043198_0	1294142.CINTURNW_1160	6.223e-104	349.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_4063726_1	518637.EUBIFOR_02485	3.846e-42	161.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,3VQCC@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
WZS3_k127_4063726_0	1041504.RATSFB_0960	2.343e-163	524.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,36DRK@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
WZS3_k127_4063726_2	439481.Aboo_0280	4.609e-09	59.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,3F34Y@33867|unclassified Euryarchaeota	28890|Euryarchaeota	M	Nucleotidyl transferase	graD2	GO:0003674,GO:0003824,GO:0003977,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0070569	2.3.1.157,2.7.7.13,2.7.7.23	ko:K00966,ko:K04042	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00416,R00885,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WZS3_k127_407845_0	994573.T472_0218945	3.402e-140	452.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,36DHF@31979|Clostridiaceae	186801|Clostridia	C	citrate synthase	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
WZS3_k127_407845_1	1123313.ATUT01000026_gene5	5.713e-07	53.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,3VNR7@526524|Erysipelotrichia	526524|Erysipelotrichia	CE	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
WZS3_k127_4080276_0	1121335.Clst_0015	2.693e-75	258.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia,3WI5Z@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WZS3_k127_4080276_1	1280676.AUJO01000031_gene3678	4.095e-37	146.0	COG1670@1|root,COG1670@2|Bacteria,1V36S@1239|Firmicutes,24FW8@186801|Clostridia,4BYSE@830|Butyrivibrio	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_4080276_2	1007096.BAGW01000031_gene33	8.905e-15	76.0	2A5CZ@1|root,30U2N@2|Bacteria,1UQ4W@1239|Firmicutes,257TM@186801|Clostridia,2N7XB@216572|Oscillospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
WZS3_k127_4080276_4	327277.JHAL01000001_gene1524	2.848e-07	56.0	2E9K0@1|root,333SV@2|Bacteria,2GW70@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4080276_5	1235755.ANAM01000010_gene1882	6.057e-06	49.0	COG2026@1|root,COG2026@2|Bacteria,1VEQK@1239|Firmicutes,4HQ2Q@91061|Bacilli	91061|Bacilli	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
WZS3_k127_4080276_3	634504.Bgr_10020	4.708e-13	69.0	COG2026@1|root,COG2026@2|Bacteria,1N76D@1224|Proteobacteria,2UF77@28211|Alphaproteobacteria,48U7C@772|Bartonellaceae	28211|Alphaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
WZS3_k127_4080276_6	1123230.ARQJ01000015_gene1018	5.418e-05	46.0	2EG8N@1|root,33A0G@2|Bacteria,1UPXN@1239|Firmicutes,4IVCR@91061|Bacilli,4H0YC@90964|Staphylococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4091177_0	1211844.CBLM010000040_gene2867	2.259e-114	376.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,3VPD7@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PHP
WZS3_k127_4092357_0	1507.HMPREF0262_02561	6.002e-108	361.0	COG3613@1|root,COG3613@2|Bacteria,1VFK6@1239|Firmicutes,24RZ5@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
WZS3_k127_4092357_1	1294142.CINTURNW_1852	1.061e-23	103.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,24B1N@186801|Clostridia,36F7Q@31979|Clostridiaceae	186801|Clostridia	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_409277_1	1121947.AUHK01000008_gene323	3.594e-44	164.0	28HBR@1|root,2Z7NQ@2|Bacteria,1TQ2N@1239|Firmicutes,24FA7@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4311
WZS3_k127_409277_4	66692.ABC1410	2.365e-08	59.0	2AJY2@1|root,31AM7@2|Bacteria,1VH0B@1239|Firmicutes,4HP7Y@91061|Bacilli,1ZIKV@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4312)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4312
WZS3_k127_409277_0	469616.FMAG_02481	1.049e-48	176.0	292C3@1|root,2ZPWH@2|Bacteria,37A4E@32066|Fusobacteria	32066|Fusobacteria	S	Glycine-rich SFCGS	-	-	-	-	-	-	-	-	-	-	-	-	Gly_rich_SFCGS
WZS3_k127_409277_3	1121024.AUCD01000008_gene2129	2.838e-10	66.0	299Q4@1|root,2ZWSE@2|Bacteria,1W5DP@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_409277_2	1232449.BAHV02000016_gene1908	2.971e-43	170.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia	186801|Clostridia	GKT	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,Mga,PRD
WZS3_k127_410485_1	679192.HMPREF9013_0792	2.436e-33	134.0	COG0421@1|root,COG0421@2|Bacteria,1TSJ4@1239|Firmicutes,3VRQW@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_410485_0	1158607.UAU_01994	1.974e-94	325.0	COG1455@1|root,COG1455@2|Bacteria,1UYES@1239|Firmicutes,4HGU1@91061|Bacilli,4B2GR@81852|Enterococcaceae	91061|Bacilli	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
WZS3_k127_410512_0	469615.FGAG_01162	5.393e-159	509.0	COG0183@1|root,COG0183@2|Bacteria,378R0@32066|Fusobacteria	32066|Fusobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS3_k127_410512_1	1410668.JNKC01000004_gene59	2.766e-118	383.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia,36DHT@31979|Clostridiaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS3_k127_410512_2	1033810.HLPCO_002057	2.436e-103	344.0	COG2267@1|root,COG2267@2|Bacteria,2NRN8@2323|unclassified Bacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
WZS3_k127_410512_3	1033810.HLPCO_002056	1.149e-96	319.0	COG0332@1|root,COG0332@2|Bacteria,2NQSU@2323|unclassified Bacteria	2|Bacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WZS3_k127_4106604_1	1294142.CINTURNW_2531	1.158e-57	203.0	COG0537@1|root,COG0537@2|Bacteria,1V7FG@1239|Firmicutes,24H6W@186801|Clostridia,36FR5@31979|Clostridiaceae	186801|Clostridia	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
WZS3_k127_4106604_3	1122917.KB899659_gene4876	2.592e-43	160.0	COG5646@1|root,COG5646@2|Bacteria,1V6QT@1239|Firmicutes,4HIUI@91061|Bacilli,26XR5@186822|Paenibacillaceae	91061|Bacilli	S	Iron chaperone	frataxin	-	-	ko:K05937	-	-	-	-	ko00000	-	-	-	DUF1801
WZS3_k127_4106604_0	1294142.CINTURNW_2776	3.284e-173	551.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,36EU1@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase	bdhA	GO:0003674,GO:0003824,GO:0004022,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	-	ko:K00100,ko:K19955	ko00650,ko01120,map00650,map01120	-	R03544,R03545	RC00087	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
WZS3_k127_4106604_4	1163617.SCD_n01147	5.57e-19	100.0	COG2202@1|root,COG3452@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3452@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,2WGSC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
WZS3_k127_4106604_2	931626.Awo_c15590	1.746e-45	182.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25UWR@186806|Eubacteriaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
WZS3_k127_4123867_14	877415.JNJQ01000003_gene1675	2.088e-58	212.0	COG0535@1|root,COG0535@2|Bacteria,1UPAB@1239|Firmicutes	1239|Firmicutes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
WZS3_k127_4123867_4	658659.HMPREF0983_03409	1.347e-99	330.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,3VNW4@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K17076	ko02010,map02010	M00589	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.20	-	-	ABC_tran
WZS3_k127_4123867_7	1121333.JMLH01000003_gene306	6.695e-77	265.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,3VNPM@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K17073,ko:K17074	ko02010,map02010	M00589	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.20	-	-	BPD_transp_1,SBP_bac_3
WZS3_k127_4123867_9	650150.ERH_0895	3.373e-74	259.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,3VNPM@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K17073,ko:K17074	ko02010,map02010	M00589	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.20	-	-	BPD_transp_1,SBP_bac_3
WZS3_k127_4123867_8	545696.HOLDEFILI_01909	8.757e-77	264.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,3VP9V@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Belongs to the TtcA family	-	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
WZS3_k127_4123867_10	545696.HOLDEFILI_01910	7.06e-73	254.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,3VPWE@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
WZS3_k127_4123867_6	658659.HMPREF0983_00973	1.818e-77	269.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,3VNRK@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
WZS3_k127_4123867_13	1121936.AUHI01000019_gene635	8.537e-60	214.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli	91061|Bacilli	P	ABC transporter	artQ	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
WZS3_k127_4123867_5	428127.EUBDOL_00077	7.135e-89	299.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes	1239|Firmicutes	E	'abc transporter, ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
WZS3_k127_4123867_15	1541959.KQ51_01184	3.569e-51	190.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	artP	-	-	ko:K02030,ko:K17073,ko:K17074	ko02010,map02010	M00236,M00589	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.20	-	-	SBP_bac_3
WZS3_k127_4123867_17	658659.HMPREF0983_00976	3.805e-15	79.0	2C7TZ@1|root,3320S@2|Bacteria,1VF4X@1239|Firmicutes	1239|Firmicutes	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
WZS3_k127_4123867_16	552396.HMPREF0863_00900	4.105e-23	103.0	COG0781@1|root,COG0781@2|Bacteria,1TTWT@1239|Firmicutes,3VRA3@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	-	-	-	-	-	-	-	-	-	NusB
WZS3_k127_4123867_3	908340.HMPREF9406_2042	1.986e-101	345.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,36EU5@31979|Clostridiaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
WZS3_k127_4123867_18	552396.HMPREF0863_00902	6.544e-14	74.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,3VS2Q@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
WZS3_k127_4123867_11	1121333.JMLH01000006_gene1277	1.525e-62	225.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,3VPX5@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
WZS3_k127_4123867_0	1211819.CALK01000007_gene2598	5.499e-239	753.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,3VNZI@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
WZS3_k127_4123867_2	1232449.BAHV02000012_gene2263	4.949e-151	495.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,268A1@186813|unclassified Clostridiales	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
WZS3_k127_4123867_12	999413.HMPREF1094_03383	4.179e-62	224.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,3VQA4@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
WZS3_k127_4123867_1	545696.HOLDEFILI_03587	2.066e-185	586.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,3VPGS@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
WZS3_k127_4123867_19	1232449.BAHV02000012_gene2285	6.513e-11	66.0	COG3227@1|root,COG3227@2|Bacteria,1W4FI@1239|Firmicutes	1239|Firmicutes	E	Domain of unknown function (DUF5011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011
WZS3_k127_4132522_2	1408422.JHYF01000004_gene1663	1.253e-19	94.0	COG2020@1|root,COG2020@2|Bacteria,1VC4U@1239|Firmicutes,24PVH@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
WZS3_k127_4132522_0	1121333.JMLH01000058_gene1712	4.597e-86	291.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,3VQ08@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_4132522_1	552396.HMPREF0863_01293	8.184e-27	113.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,3VRRC@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GntR
WZS3_k127_4132522_3	1449050.JNLE01000003_gene567	1.761e-11	68.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,36DZN@31979|Clostridiaceae	186801|Clostridia	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WZS3_k127_4137240_0	545696.HOLDEFILI_01940	6.555e-97	330.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,3VNWK@526524|Erysipelotrichia	526524|Erysipelotrichia	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
WZS3_k127_4137240_1	1232449.BAHV02000018_gene1690	3.771e-21	105.0	COG4972@1|root,COG4972@2|Bacteria	2|Bacteria	NU	Pilus assembly protein	hofM	GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K02461,ko:K02662,ko:K02663,ko:K12288	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15	-	-	PilM_2,PilN
WZS3_k127_4137240_2	552396.HMPREF0863_01137	0.000402	50.0	2DXVE@1|root,346U0@2|Bacteria,1W1WZ@1239|Firmicutes,3VU69@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4139685_6	411902.CLOBOL_04531	3.162e-13	71.0	COG1344@1|root,COG1344@2|Bacteria,1UHCZ@1239|Firmicutes,25Q3G@186801|Clostridia,21ZNK@1506553|Lachnoclostridium	186801|Clostridia	N	Bacterial flagellin N-terminal helical region	-	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_N
WZS3_k127_4139685_9	411902.CLOBOL_04530	0.0007961	48.0	28Q2I@1|root,32SZX@2|Bacteria,1VC9U@1239|Firmicutes,24P4K@186801|Clostridia,22446@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4139685_4	658086.HMPREF0994_00534	3.506e-28	120.0	COG1699@1|root,COG1699@2|Bacteria,1VA6Y@1239|Firmicutes,24QXE@186801|Clostridia,27NC5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
WZS3_k127_4139685_7	1105031.HMPREF1141_2797	3.701e-12	69.0	COG1551@1|root,COG1551@2|Bacteria	2|Bacteria	T	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding	csrA	-	-	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03019	-	-	-	CsrA
WZS3_k127_4139685_3	658086.HMPREF0994_00531	6.522e-112	390.0	COG1345@1|root,COG1345@2|Bacteria,1TQ66@1239|Firmicutes,248Q9@186801|Clostridia,27IEZ@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
WZS3_k127_4139685_5	1286171.EAL2_c03470	8.488e-23	103.0	COG1516@1|root,COG1516@2|Bacteria,1VA8K@1239|Firmicutes,24MRW@186801|Clostridia,25X2K@186806|Eubacteriaceae	186801|Clostridia	N	Flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
WZS3_k127_4139685_2	293826.Amet_2969	5.637e-120	397.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,36ES9@31979|Clostridiaceae	186801|Clostridia	T	PFAM EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
WZS3_k127_4139685_0	1211819.CALK01000033_gene1360	7.122e-224	706.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,3VNUF@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WZS3_k127_4139685_8	1211819.CALK01000033_gene1359	5.351e-09	64.0	COG2508@1|root,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	GAF,GAF_2,HTH_30,PucR
WZS3_k127_4139685_1	1211819.CALK01000033_gene1358	5.475e-188	593.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,3VNPX@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
WZS3_k127_4149795_3	1449337.JQLL01000001_gene1668	2.596e-52	196.0	COG2021@1|root,COG2021@2|Bacteria	2|Bacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	bioH	-	2.1.1.197,3.1.1.85,3.7.1.13,3.7.1.9,4.2.99.20	ko:K02169,ko:K02170,ko:K08680,ko:K10216,ko:K15756,ko:K16264	ko00130,ko00362,ko00621,ko00622,ko00643,ko00780,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map00621,map00622,map00643,map00780,map01100,map01110,map01120,map01220	M00116,M00544,M00569,M00572	R02604,R05362,R05365,R05865,R08166,R09543,R09725	RC00003,RC00272,RC00460,RC00461,RC00753,RC00754,RC00755,RC00757,RC01337,RC01485,RC02148,RC02475	br01602,ko00000,ko00001,ko00002,ko01000,ko02000	2.A.4.1	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
WZS3_k127_4149795_5	929703.KE386491_gene2804	1.216e-11	71.0	arCOG09454@1|root,30G4A@2|Bacteria,4NPSB@976|Bacteroidetes,47Q9D@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4149795_0	658659.HMPREF0983_00074	1.911e-268	844.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,3VNUS@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Tex-like protein N-terminal domain protein	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
WZS3_k127_4149795_1	1476973.JMMB01000007_gene2999	2.428e-215	677.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,25R6A@186804|Peptostreptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
WZS3_k127_4149795_4	665956.HMPREF1032_02825	1.135e-18	92.0	COG1329@1|root,COG1329@2|Bacteria,1VAA0@1239|Firmicutes,24P60@186801|Clostridia,3WK1A@541000|Ruminococcaceae	186801|Clostridia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
WZS3_k127_4149795_2	552396.HMPREF0863_01125	5.882e-61	222.0	COG0673@1|root,COG0673@2|Bacteria,1UF9V@1239|Firmicutes,3VPH1@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
WZS3_k127_4149795_7	1507.HMPREF0262_00046	2.6e-06	52.0	2EIH8@1|root,33C8K@2|Bacteria,1U4I6@1239|Firmicutes,24UNA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4149795_8	742733.HMPREF9469_00999	3.847e-06	53.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	ycnE	GO:0003674,GO:0003824	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	ABM
WZS3_k127_4149795_6	879308.HMPREF9130_0974	5.619e-07	53.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,22I4F@1570339|Peptoniphilaceae	186801|Clostridia	P	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
WZS3_k127_415402_1	306264.CUP1105	1.651e-72	253.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42NR8@68525|delta/epsilon subdivisions,2YTM9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_415402_5	1292035.H476_2592	2.034e-06	58.0	COG3714@1|root,COG3714@2|Bacteria,1VPPH@1239|Firmicutes,24PND@186801|Clostridia	186801|Clostridia	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
WZS3_k127_415402_3	1499685.CCFJ01000024_gene2216	1.056e-39	154.0	2B66C@1|root,31Z3H@2|Bacteria,1V6U0@1239|Firmicutes,4HJU5@91061|Bacilli,1ZG5C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_415402_2	1123290.AUDQ01000002_gene2405	6.636e-64	233.0	COG1503@1|root,COG1503@2|Bacteria,1UHSE@1239|Firmicutes,4HEGH@91061|Bacilli	91061|Bacilli	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_415402_0	1341151.ASZU01000003_gene2246	3.229e-101	338.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli,27CM7@186824|Thermoactinomycetaceae	91061|Bacilli	K	Bacterial transcription activator, effector binding domain	ydeE	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
WZS3_k127_415402_4	1321815.HMPREF9193_00059	1.145e-06	51.0	2BZA3@1|root,2Z7YV@2|Bacteria,2J5K9@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4162242_1	592026.GCWU0000282_000070	8.839e-43	162.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WZS3_k127_4162242_0	1211819.CALK01000006_gene2542	1.026e-102	354.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,3VPUG@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
WZS3_k127_4166979_2	1232449.BAHV02000010_gene2874	2.056e-52	191.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,267US@186813|unclassified Clostridiales	186801|Clostridia	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WZS3_k127_4166979_1	545696.HOLDEFILI_01968	2.321e-86	290.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,3VPG1@526524|Erysipelotrichia	526524|Erysipelotrichia	P	TrkA N-terminal domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WZS3_k127_4166979_3	469616.FMAG_00906	8.654e-48	182.0	COG0010@1|root,COG1982@1|root,COG0010@2|Bacteria,COG1982@2|Bacteria,379MA@32066|Fusobacteria	32066|Fusobacteria	E	Psort location Cytoplasmic, score	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase,OKR_DC_1,OKR_DC_1_C
WZS3_k127_4166979_0	1232449.BAHV02000014_gene1991	6.326e-154	496.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,268BF@186813|unclassified Clostridiales	186801|Clostridia	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WZS3_k127_4173044_0	360911.EAT1b_0454	3.422e-68	242.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,4HAUM@91061|Bacilli	91061|Bacilli	G	Major facilitator superfamily	-	-	-	ko:K08174	-	-	-	-	ko00000,ko02000	2.A.1.7	-	-	MFS_1
WZS3_k127_4173044_3	247634.GPB2148_2624	1.491e-33	135.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,1RYVB@1236|Gammaproteobacteria,1J71S@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Ferritin-like domain	ftnA	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008199,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033554,GO:0042221,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0097577,GO:0098771	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
WZS3_k127_4173044_1	1449050.JNLE01000003_gene2262	7.187e-60	216.0	COG1018@1|root,COG1018@2|Bacteria,1TREA@1239|Firmicutes,24IQR@186801|Clostridia,36IU7@31979|Clostridiaceae	186801|Clostridia	C	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4173044_2	180332.JTGN01000004_gene2566	6.604e-34	136.0	COG4912@1|root,COG4912@2|Bacteria,1TSAW@1239|Firmicutes,24GX4@186801|Clostridia	186801|Clostridia	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
WZS3_k127_4194896_0	1203606.HMPREF1526_00521	2.731e-137	447.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DUZ@31979|Clostridiaceae	186801|Clostridia	E	Aminotransferase	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS3_k127_4194896_1	935948.KE386494_gene194	6.151e-14	72.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,42G0Y@68295|Thermoanaerobacterales	186801|Clostridia	K	PFAM Transcription regulator	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
WZS3_k127_4201060_0	1235802.C823_00350	3.212e-05	55.0	COG5184@1|root,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,2486M@186801|Clostridia	186801|Clostridia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2
WZS3_k127_4205426_0	1157490.EL26_06585	3.446e-94	322.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,4H9S3@91061|Bacilli,278V4@186823|Alicyclobacillaceae	91061|Bacilli	G	Mannitol dehydrogenase C-terminal domain	mtlD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006059,GO:0006066,GO:0008150,GO:0008152,GO:0008926,GO:0009056,GO:0009987,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019400,GO:0019405,GO:0019407,GO:0019592,GO:0019594,GO:0019751,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:1901575,GO:1901615,GO:1901616	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
WZS3_k127_4205426_1	1408324.JNJK01000036_gene1621	5.555e-73	250.0	COG0794@1|root,COG0794@2|Bacteria,1UYG2@1239|Firmicutes,24DJV@186801|Clostridia,27PP6@186928|unclassified Lachnospiraceae	186801|Clostridia	M	SIS domain	hxlB	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
WZS3_k127_4205426_2	457421.CBFG_03035	2.42e-33	130.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,268XI@186813|unclassified Clostridiales	186801|Clostridia	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WZS3_k127_4207935_1	1123263.AUKY01000103_gene740	1.614e-50	192.0	COG3677@1|root,COG3677@2|Bacteria,1VDCQ@1239|Firmicutes,3VRXY@526524|Erysipelotrichia	526524|Erysipelotrichia	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595
WZS3_k127_4207935_2	1499683.CCFF01000017_gene2009	1.05e-44	168.0	COG0789@1|root,COG0789@2|Bacteria,1V6C0@1239|Firmicutes,24KFZ@186801|Clostridia,36IYF@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
WZS3_k127_4207935_0	484770.UFO1_0743	4.484e-92	308.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H3XD@909932|Negativicutes	909932|Negativicutes	S	reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_4250828_2	658659.HMPREF0983_00072	1.134e-16	80.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,3VPF1@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Transketolase, pyridine binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
WZS3_k127_4250828_1	573061.Clocel_0637	3.916e-37	147.0	COG5012@1|root,COG5012@2|Bacteria,1V5EH@1239|Firmicutes,24HIB@186801|Clostridia,36J2Q@31979|Clostridiaceae	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
WZS3_k127_4250828_0	1033810.HLPCO_001296	1.61e-101	340.0	COG4591@1|root,COG4591@2|Bacteria,2NP18@2323|unclassified Bacteria	2|Bacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
WZS3_k127_42625_5	1396.DJ87_2925	6.957e-46	170.0	2CA5R@1|root,2Z81H@2|Bacteria,1UYYB@1239|Firmicutes,4HA7J@91061|Bacilli,1ZC1G@1386|Bacillus	91061|Bacilli	S	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
WZS3_k127_42625_2	756499.Desde_0904	3.256e-57	202.0	COG0314@1|root,COG0314@2|Bacteria,1V1JC@1239|Firmicutes,24I6X@186801|Clostridia,264ZU@186807|Peptococcaceae	186801|Clostridia	H	Molybdopterin converting factor, large subunit	moaE	-	-	-	-	-	-	-	-	-	-	-	MoaE
WZS3_k127_42625_0	457396.CSBG_02333	5.038e-78	269.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,36I51@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	DUF1294,Metallophos
WZS3_k127_42625_1	1105031.HMPREF1141_0403	5.94e-65	233.0	COG2199@1|root,COG3852@1|root,COG3706@2|Bacteria,COG3852@2|Bacteria,1VADD@1239|Firmicutes,25E7Q@186801|Clostridia,36UW7@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K21022	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2,GAF_3,GGDEF,PAS_9
WZS3_k127_42625_6	1304866.K413DRAFT_1644	6.486e-20	98.0	2C9A0@1|root,32RNW@2|Bacteria,1VCQ2@1239|Firmicutes,25E1A@186801|Clostridia,36UGR@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_42625_3	1121121.KB894289_gene2665	1.862e-47	179.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,26QZP@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS3_k127_42625_7	907931.AEIZ01000002_gene587	5.434e-12	70.0	COG1416@1|root,COG1416@2|Bacteria,1VEYT@1239|Firmicutes,4HQQN@91061|Bacilli,4AY3B@81850|Leuconostocaceae	91061|Bacilli	S	DsrE/DsrF-like family	-	-	-	ko:K09004	-	-	-	-	ko00000	-	-	-	DrsE
WZS3_k127_42625_4	1511.CLOST_1822	6.432e-47	173.0	COG4290@1|root,COG4290@2|Bacteria,1V7IV@1239|Firmicutes,24JGG@186801|Clostridia,25U27@186804|Peptostreptococcaceae	186801|Clostridia	F	ribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
WZS3_k127_42625_8	553219.CAMSH0001_0712	0.0004873	46.0	COG2732@1|root,COG2732@2|Bacteria,1Q3CV@1224|Proteobacteria,42X44@68525|delta/epsilon subdivisions,2YR12@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
WZS3_k127_4263466_5	706433.HMPREF9430_01223	4.31e-59	209.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,3VQ7V@526524|Erysipelotrichia	526524|Erysipelotrichia	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
WZS3_k127_4263466_2	908340.HMPREF9406_0212	2.354e-131	424.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,36W22@31979|Clostridiaceae	186801|Clostridia	H	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
WZS3_k127_4263466_6	865861.AZSU01000001_gene331	8.682e-22	98.0	2DXUN@1|root,346QB@2|Bacteria,1W0UW@1239|Firmicutes,2523T@186801|Clostridia,36SBT@31979|Clostridiaceae	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
WZS3_k127_4263466_8	525254.HMPREF0072_2222	1.481e-09	60.0	COG0783@1|root,COG0783@2|Bacteria,1VA3K@1239|Firmicutes,24MZQ@186801|Clostridia,22H93@1570339|Peptoniphilaceae	186801|Clostridia	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
WZS3_k127_4263466_7	1408422.JHYF01000026_gene3535	1.782e-18	88.0	COG0783@1|root,COG0783@2|Bacteria,1VA3K@1239|Firmicutes,24MZQ@186801|Clostridia,36M7D@31979|Clostridiaceae	186801|Clostridia	P	Ferritin-like domain	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
WZS3_k127_4263466_3	697303.Thewi_0235	2.589e-108	358.0	COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,24DS0@186801|Clostridia	186801|Clostridia	S	Peptidoglycan binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
WZS3_k127_4263466_1	552396.HMPREF0863_01534	4.198e-220	691.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,3VNRE@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	-	-	-	-	-	-	-	-	-	-	tRNA-synt_1c
WZS3_k127_4263466_0	706433.HMPREF9430_01221	2.554e-265	835.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,3VPIN@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
WZS3_k127_4263466_4	545696.HOLDEFILI_04100	4.399e-93	313.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,3VNVR@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WZS3_k127_4274234_5	1246.JMEA01000003_gene986	9.374e-10	59.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,4AXI7@81850|Leuconostocaceae	91061|Bacilli	G	3-carboxymuconate cyclase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
WZS3_k127_4274234_4	111780.Sta7437_1396	6.344e-25	104.0	COG1773@1|root,COG1773@2|Bacteria,1GQR1@1117|Cyanobacteria	1117|Cyanobacteria	C	Rubredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
WZS3_k127_4274234_2	537013.CLOSTMETH_00904	1.973e-49	184.0	COG3738@1|root,COG3738@2|Bacteria,1V2SQ@1239|Firmicutes,24F5T@186801|Clostridia,3WNEN@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
WZS3_k127_4274234_1	693746.OBV_45320	7.038e-99	335.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,2N71P@216572|Oscillospiraceae	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	ko:K00841,ko:K10907	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00525	R04467	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS3_k127_4274234_3	428127.EUBDOL_00745	5.168e-47	176.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,3VPVD@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
WZS3_k127_4274234_0	1211819.CALK01000016_gene596	1.733e-181	580.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,3VNUF@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WZS3_k127_4295820_0	650150.ERH_1401	4.014e-147	480.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,3VNXB@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Psort location CytoplasmicMembrane, score	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
WZS3_k127_4309417_6	1511.CLOST_2510	2.53e-36	143.0	COG1246@1|root,COG1246@2|Bacteria,1UHXM@1239|Firmicutes,24TJG@186801|Clostridia	186801|Clostridia	E	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4309417_5	1211819.CALK01000044_gene934	3.184e-45	171.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,3VQJC@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Hydrolase, NUDIX family	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WZS3_k127_4309417_2	552396.HMPREF0863_00260	1.571e-82	279.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,3VQE4@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
WZS3_k127_4309417_3	1211819.CALK01000045_gene954	6.482e-67	239.0	COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,3VQHT@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA polymerase III, delta	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
WZS3_k127_4309417_0	1211819.CALK01000045_gene955	2.531e-108	357.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,3VPDE@526524|Erysipelotrichia	526524|Erysipelotrichia	S	PSP1 C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
WZS3_k127_4309417_1	545696.HOLDEFILI_02810	7.1e-108	356.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,3VP7R@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
WZS3_k127_4309417_4	1139996.OMQ_00521	1.313e-52	202.0	COG1541@1|root,COG1541@2|Bacteria,1TUIK@1239|Firmicutes,4I5QG@91061|Bacilli,4B5T0@81852|Enterococcaceae	91061|Bacilli	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4309417_7	1410668.JNKC01000001_gene1972	3.651e-30	124.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,36ICK@31979|Clostridiaceae	186801|Clostridia	P	Chromate	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WZS3_k127_4309982_1	586416.GZ22_12945	9.241e-91	302.0	COG0655@1|root,COG0655@2|Bacteria,1TSY9@1239|Firmicutes,4H9MQ@91061|Bacilli	91061|Bacilli	S	Belongs to the WrbA family	wrbA	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
WZS3_k127_4309982_0	1410668.JNKC01000003_gene496	6.092e-133	451.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
WZS3_k127_4309982_2	1262449.CP6013_2128	6.884e-06	49.0	COG0628@1|root,COG0628@2|Bacteria,1TSI9@1239|Firmicutes,25CG6@186801|Clostridia,36WVJ@31979|Clostridiaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS3_k127_4326246_0	994573.T472_0200885	1.467e-75	259.0	29VYD@1|root,30HGI@2|Bacteria,1V82C@1239|Firmicutes,24P63@186801|Clostridia,36T8X@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
WZS3_k127_4326246_2	754027.HMPREF9554_02569	1.379e-34	134.0	COG2820@1|root,COG2820@2|Bacteria,2J5TI@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_4326246_1	1095747.HMPREF1049_1803	1.619e-50	181.0	COG2820@1|root,COG2820@2|Bacteria,379GP@32066|Fusobacteria	32066|Fusobacteria	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_4331729_0	706433.HMPREF9430_00803	7.487e-100	334.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,3VPGR@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	mraW	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
WZS3_k127_4331729_1	706433.HMPREF9430_00802	3.17e-10	64.0	2EJFC@1|root,33D6B@2|Bacteria,1VQN6@1239|Firmicutes,3VSBM@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4344427_0	1469948.JPNB01000002_gene3337	4.108e-71	246.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,36F2U@31979|Clostridiaceae	186801|Clostridia	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_4344427_1	552396.HMPREF0863_02125	1.057e-30	128.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,3VQ3V@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Cof-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_4346717_0	1211819.CALK01000001_gene327	3.267e-98	323.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,3VPN2@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
WZS3_k127_4346717_2	1211844.CBLM010000105_gene1083	4.495e-46	170.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,3VR6K@526524|Erysipelotrichia	526524|Erysipelotrichia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_4346717_1	679192.HMPREF9013_0002	1.972e-52	191.0	COG1214@1|root,COG1214@2|Bacteria,1V2Y1@1239|Firmicutes,3VQIW@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Universal bacterial protein YeaZ	yeaZ	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M22
WZS3_k127_4346717_3	1121333.JMLH01000024_gene2131	2.783e-39	151.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,3VR2M@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Hydrolase, P-loop family	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
WZS3_k127_4346870_1	1158609.I586_03070	1.757e-50	185.0	COG0074@1|root,COG0074@2|Bacteria,1UHQ6@1239|Firmicutes,4H9VN@91061|Bacilli,4B0BH@81852|Enterococcaceae	91061|Bacilli	C	CoA-ligase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Ligase_CoA
WZS3_k127_4346870_3	994573.T472_0207055	6.416e-32	134.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_4346870_2	994573.T472_0207060	3.939e-46	173.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	yhgD	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K03577,ko:K09017	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_N
WZS3_k127_4346870_0	1123263.AUKY01000074_gene2047	2.394e-65	230.0	COG0421@1|root,COG0421@2|Bacteria,1TSJ4@1239|Firmicutes,3VRQW@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4354148_1	469596.HMPREF9488_00256	6.421e-77	265.0	COG1387@1|root,COG1387@2|Bacteria,1V1GR@1239|Firmicutes,3VQDT@526524|Erysipelotrichia	526524|Erysipelotrichia	E	PHP domain	-	-	-	-	-	-	-	-	-	-	-	-	PHP
WZS3_k127_4354148_0	650150.ERH_0333	3.454e-149	487.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,3VNWV@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
WZS3_k127_4354148_2	545696.HOLDEFILI_04115	6.545e-70	247.0	COG4667@1|root,COG4667@2|Bacteria,1UYZD@1239|Firmicutes,3VPBJ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
WZS3_k127_4354148_3	1385513.N780_04350	1.224e-46	171.0	COG0346@1|root,COG0346@2|Bacteria,1V6KX@1239|Firmicutes,4HJMS@91061|Bacilli,2YANX@289201|Pontibacillus	91061|Bacilli	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	yqjT	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
WZS3_k127_4354148_4	1211819.CALK01000015_gene1238	2.153e-34	134.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,3VQ7V@526524|Erysipelotrichia	526524|Erysipelotrichia	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
WZS3_k127_4359184_2	411463.EUBVEN_01937	5.345e-49	185.0	COG0449@1|root,COG0449@2|Bacteria,1V5WI@1239|Firmicutes,24IV7@186801|Clostridia	186801|Clostridia	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
WZS3_k127_4359184_3	349161.Dred_0027	5.618e-15	82.0	COG1846@1|root,COG1846@2|Bacteria,1TSQ4@1239|Firmicutes,2498J@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4359184_1	1160721.RBI_II00433	2.219e-51	191.0	28JTN@1|root,2Z9IV@2|Bacteria,1V2P2@1239|Firmicutes,24GDH@186801|Clostridia,3WHP2@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4359184_0	697303.Thewi_1529	5.59e-74	258.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,42GCS@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM class II aldolase adducin family protein	fucA	-	4.1.2.17,5.1.3.4	ko:K01628,ko:K03077	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
WZS3_k127_4359184_4	1236902.ANAS01000036_gene2021	3.248e-07	60.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria	201174|Actinobacteria	K	UbiC transcription regulator-associated domain protein	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_4374365_0	428126.CLOSPI_02028	8.927e-228	717.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,3VPGW@526524|Erysipelotrichia	526524|Erysipelotrichia	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
WZS3_k127_4374365_1	1121423.JONT01000009_gene1424	6.721e-30	123.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,260PG@186807|Peptococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
WZS3_k127_4381981_0	580327.Tthe_1857	3.417e-175	564.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,42FSS@68295|Thermoanaerobacterales	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
WZS3_k127_4384580_5	86416.Clopa_0162	2.643e-11	64.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,36EN2@31979|Clostridiaceae	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
WZS3_k127_4384580_1	1122931.AUAE01000012_gene2258	5.517e-91	305.0	COG4422@1|root,COG4422@2|Bacteria,4NJKJ@976|Bacteroidetes,2FNM4@200643|Bacteroidia,22WMA@171551|Porphyromonadaceae	976|Bacteroidetes	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
WZS3_k127_4384580_2	1410668.JNKC01000005_gene2312	1.075e-60	213.0	29D92@1|root,30070@2|Bacteria,1V50X@1239|Firmicutes,24GUJ@186801|Clostridia,36J6X@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4384580_6	1410668.JNKC01000005_gene2312	1.929e-06	56.0	29D92@1|root,30070@2|Bacteria,1V50X@1239|Firmicutes,24GUJ@186801|Clostridia,36J6X@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4384580_3	1499684.CCNP01000018_gene954	1.938e-47	183.0	COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,24GFT@186801|Clostridia,36G3K@31979|Clostridiaceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
WZS3_k127_4384580_0	877415.JNJQ01000027_gene20	2.218e-93	330.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,3VQND@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WZS3_k127_4384580_4	1267211.KI669560_gene113	2.011e-14	75.0	COG1983@1|root,COG1983@2|Bacteria,4NG3T@976|Bacteroidetes,1IPE9@117747|Sphingobacteriia	976|Bacteroidetes	KT	PFAM PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	DUF2807,PspC
WZS3_k127_4399579_4	1216362.B437_03141	9.61e-77	262.0	COG1272@1|root,COG1272@2|Bacteria,37A0Z@32066|Fusobacteria	32066|Fusobacteria	S	channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
WZS3_k127_4399579_3	1278311.AUAL01000008_gene1136	8.44e-83	279.0	COG0605@1|root,COG0605@2|Bacteria,3WTME@544448|Tenericutes	544448|Tenericutes	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
WZS3_k127_4399579_5	655812.HMPREF0061_0668	6.507e-25	111.0	COG4684@1|root,COG4684@2|Bacteria,1VB4T@1239|Firmicutes,4HMUC@91061|Bacilli,27E4R@186827|Aerococcaceae	91061|Bacilli	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
WZS3_k127_4399579_1	1410632.JHWW01000001_gene1379	6.787e-135	436.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,27IVZ@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
WZS3_k127_4399579_6	1123511.KB905839_gene345	1.676e-16	85.0	COG1959@1|root,COG1959@2|Bacteria,1V6RP@1239|Firmicutes,4H4XX@909932|Negativicutes	909932|Negativicutes	K	Transcriptional regulator	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
WZS3_k127_4399579_2	931276.Cspa_c22750	2.653e-99	334.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,36EGZ@31979|Clostridiaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	namA	-	1.6.99.1	ko:K00354	-	-	R00282	RC00001	ko00000,ko01000	-	-	-	Oxidored_FMN
WZS3_k127_4399579_0	720554.Clocl_0971	3.637e-143	466.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WGJP@541000|Ruminococcaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
WZS3_k127_4399579_7	1160721.RBI_II00374	4.287e-07	53.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WZS3_k127_4402840_1	1123304.AQYA01000031_gene2254	4.521e-81	276.0	COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4HBJW@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_4402840_2	279010.BL01849	3.285e-53	206.0	COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HCAX@91061|Bacilli,1ZBS7@1386|Bacillus	91061|Bacilli	V	ABC transporter (permease) YclI	yclI	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS3_k127_4402840_0	1347392.CCEZ01000004_gene766	5.229e-102	341.0	COG1181@1|root,COG1181@2|Bacteria,1TRW2@1239|Firmicutes,24F2R@186801|Clostridia,36IY4@31979|Clostridiaceae	186801|Clostridia	M	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
WZS3_k127_4402840_3	1123252.ATZF01000026_gene4143	2.956e-38	149.0	COG3457@1|root,COG3457@2|Bacteria,1TNYJ@1239|Firmicutes,4HBIA@91061|Bacilli	91061|Bacilli	E	Racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
WZS3_k127_4405883_1	1384066.JAGT01000001_gene666	6.13e-184	584.0	2BZA3@1|root,2Z7YV@2|Bacteria,1TSER@1239|Firmicutes,24AF5@186801|Clostridia,3WI1E@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4405883_2	877411.JMMA01000002_gene2257	1.937e-149	491.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,24NSC@186801|Clostridia,3WIB3@541000|Ruminococcaceae	186801|Clostridia	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
WZS3_k127_4405883_0	857293.CAAU_0055	1.352e-200	633.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,36HPG@31979|Clostridiaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WZS3_k127_4405883_4	1122927.KB895420_gene4144	8.655e-24	109.0	COG1309@1|root,COG1309@2|Bacteria,1TYNZ@1239|Firmicutes,4HHUA@91061|Bacilli,276CX@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_4405883_3	398512.JQKC01000001_gene2326	1.314e-34	134.0	COG2207@1|root,COG2207@2|Bacteria,1TQDS@1239|Firmicutes,24907@186801|Clostridia,3WGSU@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WZS3_k127_4405897_4	1227352.C173_27180	2.458e-92	312.0	COG1079@1|root,COG1079@2|Bacteria,1UY4K@1239|Firmicutes,4HVQN@91061|Bacilli,26S6E@186822|Paenibacillaceae	91061|Bacilli	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
WZS3_k127_4405897_1	1487921.DP68_05520	1.756e-119	394.0	COG4603@1|root,COG4603@2|Bacteria,1UNT4@1239|Firmicutes,24CQN@186801|Clostridia,36G0D@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
WZS3_k127_4405897_0	1321784.HMPREF1987_01971	1.173e-184	591.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,25QC2@186804|Peptostreptococcaceae	186801|Clostridia	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
WZS3_k127_4405897_3	1219084.AP014508_gene898	2.171e-94	321.0	COG1744@1|root,COG1744@2|Bacteria,2GCUG@200918|Thermotogae	200918|Thermotogae	S	PFAM Basic membrane	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
WZS3_k127_4405897_5	1391646.AVSU01000109_gene678	2.25e-44	168.0	COG2249@1|root,COG2249@2|Bacteria,1VB36@1239|Firmicutes,25CB0@186801|Clostridia	186801|Clostridia	S	NADPH-quinone reductase (modulator of drug activity B)	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
WZS3_k127_4405897_2	1232449.BAHV02000002_gene126	2.199e-108	364.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,247ZP@186801|Clostridia	186801|Clostridia	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_4405897_6	933262.AXAM01000028_gene3306	8.507e-13	78.0	COG2188@1|root,COG2188@2|Bacteria,1Q856@1224|Proteobacteria,42X73@68525|delta/epsilon subdivisions,2WYE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	UTRA domain	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_4428688_1	877415.JNJQ01000006_gene898	1.354e-97	337.0	COG1263@1|root,COG1263@2|Bacteria,1UYEQ@1239|Firmicutes,3VPH7@526524|Erysipelotrichia	526524|Erysipelotrichia	G	PTS System	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIB,PTS_EIIC
WZS3_k127_4428688_0	545696.HOLDEFILI_01271	3.915e-109	366.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,3VP96@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Cell cycle protein, FtsW RodA SpoVE family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
WZS3_k127_4428688_2	1211819.CALK01000046_gene1715	8.742e-37	142.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,3VP02@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
WZS3_k127_4435429_2	650150.ERH_1001	8.872e-68	234.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,3VP2X@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
WZS3_k127_4435429_3	545696.HOLDEFILI_03729	8.046e-57	214.0	COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,3VNXA@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Peptidase M16 inactive domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16_C
WZS3_k127_4435429_1	545696.HOLDEFILI_03730	5.644e-99	337.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,3VP3P@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
WZS3_k127_4435429_5	471223.GWCH70_3137	3.545e-27	114.0	COG0629@1|root,COG0629@2|Bacteria,1V797@1239|Firmicutes,4HJFJ@91061|Bacilli,1WHSR@129337|Geobacillus	91061|Bacilli	L	Single-strand binding protein family	ssbB	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WZS3_k127_4435429_0	1121874.KB892377_gene1393	2.126e-130	422.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,3VPGH@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
WZS3_k127_4435429_4	1129368.SMIPMB4A_v3c8370	1.034e-35	141.0	COG0262@1|root,COG0262@2|Bacteria,3WTRF@544448|Tenericutes	544448|Tenericutes	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
WZS3_k127_4446743_3	318464.IO99_01390	7.992e-29	119.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,36KP1@31979|Clostridiaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
WZS3_k127_4446743_1	595494.Tola_1326	7.567e-80	276.0	COG0657@1|root,COG0657@2|Bacteria,1R41U@1224|Proteobacteria,1RW6M@1236|Gammaproteobacteria,1Y5RR@135624|Aeromonadales	135624|Aeromonadales	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
WZS3_k127_4446743_2	1121430.JMLG01000004_gene815	2.577e-31	126.0	COG1592@1|root,COG1592@2|Bacteria,1VB12@1239|Firmicutes,24JQ6@186801|Clostridia,262FT@186807|Peptococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4446743_0	445974.CLORAM_01491	2.906e-237	741.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,3VPAF@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Belongs to the glycosyl hydrolase 1 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_1
WZS3_k127_4446743_5	1280954.HPO_18425	7.64e-16	81.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2UAVD@28211|Alphaproteobacteria,43ZVQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4446743_4	1541959.KQ51_00707	7.692e-26	109.0	COG1695@1|root,COG1695@2|Bacteria,3WUTE@544448|Tenericutes	544448|Tenericutes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WZS3_k127_4446743_6	431943.CKL_2541	2.134e-15	87.0	COG0604@1|root,COG0604@2|Bacteria,1TT5J@1239|Firmicutes,24IEA@186801|Clostridia,36KEU@31979|Clostridiaceae	186801|Clostridia	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4446743_7	1298598.JCM21714_55	9.189e-07	52.0	COG1266@1|root,COG1266@2|Bacteria,1V47I@1239|Firmicutes,4IC6Y@91061|Bacilli,471F8@74385|Gracilibacillus	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WZS3_k127_446678_1	1385513.N780_17840	6.288e-93	316.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,2YA4D@289201|Pontibacillus	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rlmCD	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WZS3_k127_446678_3	650150.ERH_0343	5.05e-25	112.0	29TY8@1|root,30F75@2|Bacteria,1V48Z@1239|Firmicutes,3VR2D@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_446678_0	1211819.CALK01000015_gene1230	3.8e-196	622.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,3VP87@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
WZS3_k127_446678_2	545696.HOLDEFILI_03966	3.863e-31	124.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,3VPCY@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
WZS3_k127_4467206_1	702450.CUW_1693	2.236e-52	193.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,3VQBN@526524|Erysipelotrichia	526524|Erysipelotrichia	J	RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
WZS3_k127_4467206_0	999413.HMPREF1094_03141	1.908e-148	479.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,3VNU5@526524|Erysipelotrichia	526524|Erysipelotrichia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
WZS3_k127_4477475_0	445335.CBN_0159	9.905e-107	356.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,36EVH@31979|Clostridiaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
WZS3_k127_4477475_5	1045856.EcWSU1_03040	3.104e-34	141.0	COG1174@1|root,COG1174@2|Bacteria,1MX8D@1224|Proteobacteria,1RSDR@1236|Gammaproteobacteria,3X1T1@547|Enterobacter	1236|Gammaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	yehW	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0016020,GO:0031460,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0072337	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iEC042_1314.EC042_2361,iECUMN_1333.ECUMN_2462	BPD_transp_1
WZS3_k127_4477475_2	522772.Dacet_2436	8.675e-78	271.0	COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,2GF8A@200930|Deferribacteres	200930|Deferribacteres	E	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
WZS3_k127_4477475_4	1410668.JNKC01000004_gene160	6.148e-53	201.0	COG1174@1|root,COG1174@2|Bacteria,1UHWH@1239|Firmicutes,25E5C@186801|Clostridia,36VQG@31979|Clostridiaceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
WZS3_k127_4477475_1	1410668.JNKC01000004_gene161	5.046e-81	280.0	COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,248A1@186801|Clostridia,36DBY@31979|Clostridiaceae	186801|Clostridia	P	glycine, betaine	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
WZS3_k127_4477475_3	545696.HOLDEFILI_03074	6.323e-73	252.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,3VPSU@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Phosphogluconate dehydrogenase (Decarboxylating), NAD binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
WZS3_k127_4488470_1	658086.HMPREF0994_07062	2.346e-28	119.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,27S0W@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Sulfite exporter TauE/SafE	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
WZS3_k127_4488470_0	545696.HOLDEFILI_04081	1.163e-40	156.0	COG0847@1|root,COG0847@2|Bacteria,1V57H@1239|Firmicutes,3VQWS@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA polymerase III, epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	BRCT,RNase_T
WZS3_k127_4489207_0	1211819.CALK01000004_gene2320	3.513e-182	593.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,3VP38@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Penicillin-binding protein, transpeptidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP_dimer,Transpeptidase
WZS3_k127_4489207_1	1211819.CALK01000004_gene2318	9.748e-149	480.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,3VPBF@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	-	-	-	-	-	-	-	-	-	-	GcpE
WZS3_k127_4489207_3	679192.HMPREF9013_0484	4.596e-102	347.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,3VP7M@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DEAD DEAH box helicase	cshB	-	3.6.4.13	ko:K18692	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	DEAD,Helicase_C
WZS3_k127_4489207_4	518637.EUBIFOR_01169	1.914e-91	309.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,3VP4I@526524|Erysipelotrichia	526524|Erysipelotrichia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	-	-	-	-	-	-	-	-	-	-	LYTB
WZS3_k127_4489207_5	1487921.DP68_08650	5.353e-31	130.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,36FNA@31979|Clostridiaceae	186801|Clostridia	S	SAM-dependent methyltransferase	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
WZS3_k127_4489207_2	658659.HMPREF0983_01033	1.622e-141	451.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,3VP72@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS3_k127_4493591_2	1195236.CTER_2191	2.005e-25	109.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,3WPKE@541000|Ruminococcaceae	186801|Clostridia	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
WZS3_k127_4493591_0	290402.Cbei_4643	1.019e-208	657.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,36DZU@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
WZS3_k127_4493591_3	1280692.AUJL01000002_gene2797	6.98e-06	50.0	COG0454@1|root,COG0456@2|Bacteria,1UHZS@1239|Firmicutes,25E8H@186801|Clostridia,36UWJ@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_4493591_1	1278306.KB906922_gene1757	1.033e-45	167.0	COG0454@1|root,COG0454@2|Bacteria,37ACV@32066|Fusobacteria	32066|Fusobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_4493758_0	903814.ELI_0521	6.395e-126	416.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia,25VXP@186806|Eubacteriaceae	186801|Clostridia	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
WZS3_k127_4493758_1	195103.CPF_2632	1.644e-43	161.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia,36ET0@31979|Clostridiaceae	186801|Clostridia	E	oligoendopeptidase, M3 family	pz-A	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
WZS3_k127_4494976_1	1121947.AUHK01000008_gene322	2.42e-33	130.0	2CHGF@1|root,2Z7QV@2|Bacteria,1TRJJ@1239|Firmicutes,24KRU@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4310)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4310
WZS3_k127_4494976_0	526218.Sterm_0675	1.98e-68	242.0	COG3964@1|root,COG3964@2|Bacteria,379KK@32066|Fusobacteria	32066|Fusobacteria	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
WZS3_k127_4500585_4	760011.Spico_0255	9.31e-37	140.0	COG4430@1|root,COG4430@2|Bacteria,2JAZJ@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
WZS3_k127_4500585_0	714961.BFZC1_10402	5.201e-71	245.0	28H95@1|root,2Z7KY@2|Bacteria,1TQTR@1239|Firmicutes,4HB82@91061|Bacilli,3IW1W@400634|Lysinibacillus	91061|Bacilli	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
WZS3_k127_4500585_2	445974.CLORAM_03058	2.355e-49	181.0	28MX3@1|root,2ZB49@2|Bacteria,1V7PT@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
WZS3_k127_4500585_5	660470.Theba_2260	8.335e-36	141.0	2DKYA@1|root,30VCV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4500585_6	908337.HMPREF9257_1087	2.921e-35	138.0	COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,4HKCB@91061|Bacilli,27ETK@186827|Aerococcaceae	91061|Bacilli	F	NUDIX domain	apfA	-	3.6.1.61	ko:K18445	ko00230,map00230	-	R00184	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
WZS3_k127_4500585_1	1123511.KB905856_gene2099	3.514e-52	191.0	COG1357@1|root,COG1357@2|Bacteria,1VAPB@1239|Firmicutes,4H6DE@909932|Negativicutes	909932|Negativicutes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide_4
WZS3_k127_4500585_3	586416.GZ22_17260	2.46e-37	145.0	293T3@1|root,2ZR8H@2|Bacteria,1V593@1239|Firmicutes,4HG8Q@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF2975)	yoaS	-	-	-	-	-	-	-	-	-	-	-	DUF2975
WZS3_k127_4500585_7	935837.JAEK01000028_gene1833	9.676e-32	124.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,4HKR7@91061|Bacilli,1ZHUY@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
WZS3_k127_4500585_8	717606.PaecuDRAFT_2046	2.466e-16	84.0	2CA5R@1|root,2Z81H@2|Bacteria,1UYYB@1239|Firmicutes,4HA7J@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
WZS3_k127_4502601_1	1410631.JHWZ01000018_gene2234	9.072e-102	338.0	COG3550@1|root,COG3550@2|Bacteria,1TPD4@1239|Firmicutes,24AYN@186801|Clostridia,27KTJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pfam:CtkA_N	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
WZS3_k127_4502601_2	1410631.JHWZ01000018_gene2233	9.078e-41	161.0	2EFK7@1|root,339CG@2|Bacteria,1UDRE@1239|Firmicutes,25IIH@186801|Clostridia,27SAW@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4502601_0	1232449.BAHV02000014_gene2059	3.616e-163	516.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,26837@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
WZS3_k127_4503051_0	1232449.BAHV02000010_gene2871	7.414e-145	464.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,268GY@186813|unclassified Clostridiales	186801|Clostridia	F	Permease family	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
WZS3_k127_4503051_1	1410668.JNKC01000005_gene2194	5.203e-29	122.0	COG3307@1|root,COG3307@2|Bacteria,1V6KK@1239|Firmicutes,25BNJ@186801|Clostridia,36WKX@31979|Clostridiaceae	186801|Clostridia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
WZS3_k127_4515263_1	1211819.CALK01000012_gene312	1.819e-83	282.0	COG0666@1|root,COG0666@2|Bacteria,1V2DE@1239|Firmicutes,3VP39@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Ankyrin repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_5
WZS3_k127_4515263_0	545696.HOLDEFILI_01605	5.155e-319	989.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,3VNX3@526524|Erysipelotrichia	526524|Erysipelotrichia	J	translation elongation and release factors (GTPases) K02355	-	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
WZS3_k127_4515263_2	857293.CAAU_0414	1.81e-16	81.0	COG0524@1|root,COG1522@1|root,COG0524@2|Bacteria,COG1522@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,36F1Z@31979|Clostridiaceae	186801|Clostridia	G	hmm pf00294	rbsK	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
WZS3_k127_4529566_1	1121874.KB892379_gene320	2.73e-58	208.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,3VQ1H@526524|Erysipelotrichia	526524|Erysipelotrichia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
WZS3_k127_4529566_2	545696.HOLDEFILI_00748	2.086e-28	115.0	COG0636@1|root,COG0636@2|Bacteria,1VEHP@1239|Firmicutes,3VRWB@526524|Erysipelotrichia	526524|Erysipelotrichia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
WZS3_k127_4529566_3	1211844.CBLM010000046_gene572	5.485e-28	119.0	COG0711@1|root,COG0711@2|Bacteria,1TTQY@1239|Firmicutes,3VQYH@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_B
WZS3_k127_4529566_4	935837.JAEK01000003_gene4088	4.483e-24	108.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKFW@91061|Bacilli,1ZG65@1386|Bacillus	91061|Bacilli	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
WZS3_k127_4529566_0	1232449.BAHV02000006_gene899	1.101e-235	737.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,2684Y@186813|unclassified Clostridiales	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
WZS3_k127_4531187_0	1511.CLOST_0728	4.378e-71	244.0	COG2203@1|root,COG3437@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
WZS3_k127_4531187_1	526218.Sterm_3224	2.866e-61	216.0	COG0406@1|root,COG0406@2|Bacteria,37BYT@32066|Fusobacteria	32066|Fusobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
WZS3_k127_4533308_0	908340.HMPREF9406_3618	9.263e-128	413.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,36HHS@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
WZS3_k127_4533308_1	908340.HMPREF9406_3619	2.169e-75	256.0	COG1653@1|root,COG1653@2|Bacteria,1V1GE@1239|Firmicutes,24B62@186801|Clostridia	186801|Clostridia	G	ABC transporter periplasmic binding protein YcjN precursor	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
WZS3_k127_4533661_1	1235835.C814_00577	8.532e-106	360.0	COG3458@1|root,COG3458@2|Bacteria,1TS02@1239|Firmicutes,24A6N@186801|Clostridia,3WJK8@541000|Ruminococcaceae	186801|Clostridia	Q	PFAM Acetyl xylan esterase	axe1	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
WZS3_k127_4533661_0	883114.HMPREF9709_01435	2.146e-119	391.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia,22G6B@1570339|Peptoniphilaceae	186801|Clostridia	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
WZS3_k127_4533661_3	393480.FNP_0427	2.71e-81	277.0	COG3010@1|root,COG3010@2|Bacteria,3799P@32066|Fusobacteria	32066|Fusobacteria	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
WZS3_k127_4533661_4	1123308.KB904541_gene1833	1.121e-19	94.0	COG2731@1|root,COG2731@2|Bacteria,1VIQH@1239|Firmicutes,4I03Z@91061|Bacilli	91061|Bacilli	G	YhcH YjgK YiaL family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
WZS3_k127_4533661_2	718252.FP2_10520	7.616e-98	331.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WZS3_k127_4538404_0	1232449.BAHV02000018_gene1684	1.562e-112	372.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,267JB@186813|unclassified Clostridiales	186801|Clostridia	NU	Type II/IV secretion system protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
WZS3_k127_4538404_1	1341157.RF007C_13855	2.766e-107	356.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,3WGU2@541000|Ruminococcaceae	186801|Clostridia	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
WZS3_k127_4543254_1	931626.Awo_c03810	3.524e-24	113.0	COG2755@1|root,COG2755@2|Bacteria,1VIQE@1239|Firmicutes,24R5V@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
WZS3_k127_4543254_0	622312.ROSEINA2194_00212	4.435e-48	177.0	COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,25B3M@186801|Clostridia	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
WZS3_k127_4563076_2	279010.BL03844	1.289e-85	287.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9Z4@91061|Bacilli,1ZC6U@1386|Bacillus	91061|Bacilli	G	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases	licH	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WZS3_k127_4563076_5	1145276.T479_04120	1.409e-36	149.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli,3IWYI@400634|Lysinibacillus	91061|Bacilli	S	Hydrolase Cof	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_4563076_3	469596.HMPREF9488_00131	5.07e-56	204.0	COG3394@1|root,COG3394@2|Bacteria,1V3MB@1239|Firmicutes,3VPTA@526524|Erysipelotrichia	526524|Erysipelotrichia	G	YdjC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
WZS3_k127_4563076_8	1415775.U729_1988	3.344e-07	55.0	2BRUK@1|root,32KUT@2|Bacteria,1UQHJ@1239|Firmicutes,24U0M@186801|Clostridia,36M9M@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	-
WZS3_k127_4563076_1	1408437.JNJN01000025_gene650	1.765e-114	385.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,25WRR@186806|Eubacteriaceae	186801|Clostridia	G	Phosphotransferase system, EIIC	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	EAL,PTS_EIIC
WZS3_k127_4563076_4	585394.RHOM_14745	6.874e-46	180.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS3_k127_4563076_0	1005058.UMN179_00806	5.644e-190	606.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	asparagine synthase, glutamine-hydrolyzing	asnB	GO:0000166,GO:0003674,GO:0003824,GO:0004066,GO:0004071,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006541,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016054,GO:0016211,GO:0016597,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0017076,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	iB21_1397.B21_00622,iECBD_1354.ECBD_2988,iECB_1328.ECB_00631,iECD_1391.ECD_00631,iEcHS_1320.EcHS_A0717,iEcolC_1368.EcolC_2982,iSF_1195.SF0619	Asn_synthase,GATase_7
WZS3_k127_4563076_7	545696.HOLDEFILI_04124	3.954e-28	118.0	COG1670@1|root,COG1670@2|Bacteria,1UM1I@1239|Firmicutes,3VRAY@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
WZS3_k127_4563076_6	526218.Sterm_3942	1.775e-31	134.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	ywpJ_2	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_4564533_2	1408422.JHYF01000003_gene832	3.76e-158	508.0	COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,24AZH@186801|Clostridia,36E6V@31979|Clostridiaceae	186801|Clostridia	CP	Proton-conducting membrane transporter	-	-	-	ko:K05568,ko:K12141	-	-	-	-	ko00000,ko01000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
WZS3_k127_4564533_1	1408422.JHYF01000003_gene833	5.511e-173	566.0	COG0651@1|root,COG0651@2|Bacteria,1TREH@1239|Firmicutes,248TK@186801|Clostridia,36EZ5@31979|Clostridiaceae	186801|Clostridia	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
WZS3_k127_4564533_0	272626.lin2292	2.228e-185	587.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli,26JZR@186820|Listeriaceae	91061|Bacilli	E	Oligopeptidase F	pepF	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
WZS3_k127_4570697_1	397287.C807_01570	1.06e-187	594.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,27I7J@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
WZS3_k127_4570697_0	665956.HMPREF1032_01351	3.222e-211	664.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3WGT3@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
WZS3_k127_4570697_3	545696.HOLDEFILI_00187	2.634e-31	127.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	DUF3795,OsmC
WZS3_k127_4570697_2	1232449.BAHV02000010_gene2874	1.618e-124	413.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,267US@186813|unclassified Clostridiales	186801|Clostridia	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
WZS3_k127_4570697_4	1157490.EL26_22520	9.561e-08	53.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli,27APN@186823|Alicyclobacillaceae	91061|Bacilli	P	TrkA-C domain	ktrA	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
WZS3_k127_4571996_0	1280689.AUJC01000001_gene2380	1.069e-62	218.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,24A0K@186801|Clostridia,36DJ3@31979|Clostridiaceae	186801|Clostridia	G	PTS system mannose fructose sorbose family IID component	agaD	-	-	ko:K02747	ko00052,ko02060,map00052,map02060	M00277	R08366	RC00017	ko00000,ko00001,ko00002,ko02000	4.A.6.1.4	-	-	EIID-AGA
WZS3_k127_4571996_1	545696.HOLDEFILI_00630	8.234e-23	106.0	COG3356@1|root,COG3356@2|Bacteria,1V598@1239|Firmicutes,3VQZE@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
WZS3_k127_4576825_0	877411.JMMA01000002_gene2934	5.293e-61	225.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
WZS3_k127_4576825_2	290402.Cbei_4563	6.442e-29	125.0	COG2188@1|root,COG2188@2|Bacteria,1UYYY@1239|Firmicutes,25B8F@186801|Clostridia,36WBC@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_4576825_3	411463.EUBVEN_01938	2.363e-28	123.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,25ZNZ@186806|Eubacteriaceae	186801|Clostridia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_4576825_4	411463.EUBVEN_01938	1.829e-27	121.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,25ZNZ@186806|Eubacteriaceae	186801|Clostridia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_4576825_1	903814.ELI_1941	1.513e-30	131.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,25ZNZ@186806|Eubacteriaceae	186801|Clostridia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_4576825_5	391009.Tmel_1544	3.116e-25	108.0	COG2265@1|root,COG2265@2|Bacteria,2GCAD@200918|Thermotogae	200918|Thermotogae	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
WZS3_k127_457740_0	1329516.JPST01000028_gene3288	9.154e-202	636.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9Z4@91061|Bacilli,27BIV@186824|Thermoactinomycetaceae	91061|Bacilli	G	Family 4 glycosyl hydrolase	licH	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
WZS3_k127_457740_1	1294142.CINTURNW_4297	1.505e-29	120.0	COG1440@1|root,COG1440@2|Bacteria,1VADE@1239|Firmicutes,24R71@186801|Clostridia,36M9S@31979|Clostridiaceae	186801|Clostridia	G	system, Lactose	-	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
WZS3_k127_457740_2	1123009.AUID01000028_gene338	3.19e-12	66.0	COG1977@1|root,COG1977@2|Bacteria,1VIST@1239|Firmicutes,24QYP@186801|Clostridia,26C3V@186813|unclassified Clostridiales	186801|Clostridia	H	ThiS family	moaD	-	-	-	-	-	-	-	-	-	-	-	ThiS
WZS3_k127_4599091_0	994573.T472_0207665	4.885e-140	457.0	COG1233@1|root,COG1233@2|Bacteria,1UU71@1239|Firmicutes	1239|Firmicutes	Q	Phytoene dehydrogenase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
WZS3_k127_4600882_7	991.IW20_21245	2.943e-44	163.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	ygcE	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WZS3_k127_4600882_3	1265505.ATUG01000002_gene1419	9.339e-136	435.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,42S4A@68525|delta/epsilon subdivisions,2WNE7@28221|Deltaproteobacteria,2MNNY@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
WZS3_k127_4600882_6	656519.Halsa_0520	3.359e-79	275.0	COG2025@1|root,COG2025@2|Bacteria,1UZWQ@1239|Firmicutes,24FEM@186801|Clostridia	186801|Clostridia	C	Electron transfer flavoprotein FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
WZS3_k127_4600882_4	656519.Halsa_0519	5.538e-93	312.0	COG2086@1|root,COG2086@2|Bacteria,1V4NW@1239|Firmicutes,24IN8@186801|Clostridia	186801|Clostridia	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF
WZS3_k127_4600882_1	1195236.CTER_1474	2.152e-154	498.0	COG2223@1|root,COG2223@2|Bacteria,1VRDN@1239|Firmicutes,24ZF4@186801|Clostridia	186801|Clostridia	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS3_k127_4600882_0	1410668.JNKC01000002_gene2116	6.175e-274	847.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,36DRC@31979|Clostridiaceae	186801|Clostridia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
WZS3_k127_4600882_5	656519.Halsa_0526	6.847e-83	281.0	COG1737@1|root,COG1737@2|Bacteria,1V524@1239|Firmicutes,24IJV@186801|Clostridia	186801|Clostridia	K	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS
WZS3_k127_4600882_2	1410619.SRDD_37930	1.719e-147	478.0	COG2223@1|root,COG2223@2|Bacteria,1QWC7@1224|Proteobacteria,1T2TH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS3_k127_4629210_2	1121121.KB894308_gene196	4.169e-34	136.0	COG2910@1|root,COG2910@2|Bacteria,1TZ3T@1239|Firmicutes,4HAJ4@91061|Bacilli,26TG0@186822|Paenibacillaceae	91061|Bacilli	S	3-beta hydroxysteroid dehydrogenase	ywnB	-	-	ko:K07118	-	-	-	-	ko00000	-	-	-	NAD_binding_10
WZS3_k127_4629210_1	698758.AXY_01690	2.766e-70	255.0	COG2815@1|root,COG2815@2|Bacteria,1V00M@1239|Firmicutes,4HD0Y@91061|Bacilli	91061|Bacilli	S	PASTA	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA
WZS3_k127_4629210_0	1123315.AUIP01000019_gene2208	4.031e-101	333.0	COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4HBJW@91061|Bacilli	91061|Bacilli	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
WZS3_k127_4629210_3	1121929.KB898672_gene4096	2.588e-16	81.0	COG0577@1|root,COG0577@2|Bacteria,1V13I@1239|Firmicutes,4HEAI@91061|Bacilli	91061|Bacilli	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS3_k127_46662_1	545696.HOLDEFILI_03271	8.675e-199	635.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,3VNSY@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
WZS3_k127_46662_3	545696.HOLDEFILI_01567	4.258e-91	313.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,3VPQ2@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
WZS3_k127_46662_0	545696.HOLDEFILI_01568	6.287e-275	862.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,3VP2F@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
WZS3_k127_46662_6	1232449.BAHV02000018_gene1649	2.443e-22	98.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nifU	-	-	ko:K07126,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
WZS3_k127_46662_4	545696.HOLDEFILI_01576	9.029e-62	218.0	COG1963@1|root,COG1963@2|Bacteria,1VAVC@1239|Firmicutes,3VQWC@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
WZS3_k127_46662_5	679192.HMPREF9013_0025	1.185e-29	123.0	COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,3VRDZ@526524|Erysipelotrichia	526524|Erysipelotrichia	J	General stress protein 13	-	-	-	-	-	-	-	-	-	-	-	-	S1
WZS3_k127_46662_2	552396.HMPREF0863_02494	1.159e-176	563.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,3VPFH@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,S1
WZS3_k127_4683704_0	545696.HOLDEFILI_02994	8.356e-32	127.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,3VPCI@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location CytoplasmicMembrane, score 10.00	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
WZS3_k127_4683704_1	877415.JNJQ01000035_gene1195	2.6e-12	79.0	COG2815@1|root,COG2815@2|Bacteria	2|Bacteria	G	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA
WZS3_k127_4730908_0	1196324.A374_13605	1.318e-83	280.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli	91061|Bacilli	S	abc transporter atp-binding protein	yheS_1	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
WZS3_k127_4730908_2	469618.FVAG_02267	2.468e-43	162.0	COG0454@1|root,COG0456@2|Bacteria,37APN@32066|Fusobacteria	32066|Fusobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
WZS3_k127_4730908_1	203119.Cthe_0219	4.021e-47	176.0	COG3467@1|root,COG3467@2|Bacteria,1VB7Q@1239|Firmicutes,24MUQ@186801|Clostridia,3WJXN@541000|Ruminococcaceae	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
WZS3_k127_4742151_8	315749.Bcer98_3958	8.473e-43	165.0	COG3279@1|root,COG3279@2|Bacteria,1V14X@1239|Firmicutes,4HDIC@91061|Bacilli,1ZC3U@1386|Bacillus	91061|Bacilli	T	COG3279 Response regulator of the LytR AlgR family	lytT	GO:0000156,GO:0000160,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
WZS3_k127_4742151_0	903814.ELI_0465	2.414e-219	689.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,25V2R@186806|Eubacteriaceae	186801|Clostridia	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
WZS3_k127_4742151_2	428127.EUBDOL_01384	1.775e-104	349.0	COG1304@1|root,COG1304@2|Bacteria,1TPC4@1239|Firmicutes,3VPPE@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
WZS3_k127_4742151_3	28377.ENSACAP00000002887	1.435e-96	331.0	COG0415@1|root,KOG0133@2759|Eukaryota,38EHG@33154|Opisthokonta,3BH22@33208|Metazoa,3CX79@33213|Bilateria,485IS@7711|Chordata,49865@7742|Vertebrata	33208|Metazoa	LT	DNA photolyase	phr	GO:0000719,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
WZS3_k127_4742151_9	411483.FAEPRAA2165_01654	3.224e-27	113.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3WKB9@541000|Ruminococcaceae	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
WZS3_k127_4742151_5	1278304.JAFR01000011_gene986	5.609e-68	239.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	aatB	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
WZS3_k127_4742151_7	926561.KB900617_gene1727	3.786e-47	177.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3WBCC@53433|Halanaerobiales	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
WZS3_k127_4742151_6	523794.Lebu_1838	6.431e-52	191.0	COG1126@1|root,COG1126@2|Bacteria,37BNF@32066|Fusobacteria	32066|Fusobacteria	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
WZS3_k127_4742151_1	865861.AZSU01000003_gene1526	8.569e-212	674.0	COG5012@1|root,COG5012@2|Bacteria,1UZP9@1239|Firmicutes,24CTM@186801|Clostridia,36GII@31979|Clostridiaceae	186801|Clostridia	S	Cobalamin B12-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4742151_4	1507.HMPREF0262_01298	4.467e-70	249.0	COG0240@1|root,COG0240@2|Bacteria,1TUSI@1239|Firmicutes,249QW@186801|Clostridia,36HVI@31979|Clostridiaceae	186801|Clostridia	C	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain	odh	-	1.5.1.28	ko:K04940	-	-	-	-	ko00000,ko01000	-	-	-	ApbA,NAD_Gly3P_dh_N,NAD_binding_2,Octopine_DH
WZS3_k127_4761202_0	1029718.SFBM_0709	6.512e-117	398.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,36F0A@31979|Clostridiaceae	186801|Clostridia	GKT	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
WZS3_k127_4761202_1	1229276.DI53_0518	3.303e-25	118.0	COG0561@1|root,COG0561@2|Bacteria,4NEG2@976|Bacteroidetes,1IS5E@117747|Sphingobacteriia	976|Bacteroidetes	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_4765789_3	706433.HMPREF9430_00578	3.364e-12	66.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,3VQE1@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WZS3_k127_4765789_2	941639.BCO26_1088	2.079e-20	98.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli,1ZD4A@1386|Bacillus	91061|Bacilli	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
WZS3_k127_4765789_1	706433.HMPREF9430_00580	5.019e-29	118.0	COG0227@1|root,COG0227@2|Bacteria,1TU2H@1239|Firmicutes,3VRNQ@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
WZS3_k127_4765789_0	545696.HOLDEFILI_01766	3.114e-53	194.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,3VNTD@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
WZS3_k127_4774895_1	1211819.CALK01000004_gene2163	1.369e-169	537.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,3VP90@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
WZS3_k127_4774895_5	469596.HMPREF9488_01731	1.271e-34	139.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,3VR0P@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Competence-damaged protein	-	-	-	-	-	-	-	-	-	-	-	-	CinA
WZS3_k127_4774895_2	1211819.CALK01000004_gene2161	8.026e-68	235.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,3VQDX@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
WZS3_k127_4774895_4	1211819.CALK01000004_gene2160	1.224e-43	170.0	COG1426@1|root,COG1426@2|Bacteria,1TTY2@1239|Firmicutes,3VRCJ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
WZS3_k127_4774895_6	908340.HMPREF9406_1528	3.965e-14	76.0	COG3599@1|root,COG3599@2|Bacteria,1UTHR@1239|Firmicutes,2532I@186801|Clostridia	186801|Clostridia	D	DivIVA protein	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
WZS3_k127_4774895_3	1211819.CALK01000004_gene2158	7.814e-61	217.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,3VQNZ@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
WZS3_k127_4774895_0	1211819.CALK01000004_gene2157	1.598e-266	849.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,3VP75@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Extracellular, score	ponA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	FIVAR,Transgly,Transpeptidase
WZS3_k127_4779200_2	994573.T472_0205165	1.762e-09	58.0	COG2253@1|root,COG2253@2|Bacteria,1TS2W@1239|Firmicutes,24EV3@186801|Clostridia,36RS0@31979|Clostridiaceae	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WZS3_k127_4779200_0	871963.Desdi_0679	7.67e-151	487.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,249X1@186801|Clostridia,2649J@186807|Peptococcaceae	186801|Clostridia	C	Alcohol dehydrogenase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
WZS3_k127_4779200_1	1487923.DP73_13755	1.264e-33	131.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,260S3@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WZS3_k127_4787595_7	903814.ELI_0730	2.842e-42	159.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,25VFK@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS3_k127_4787595_2	1280682.AUKA01000001_gene1514	3.166e-86	300.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,4BWEW@830|Butyrivibrio	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
WZS3_k127_4787595_5	350688.Clos_2306	6.258e-62	226.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,36ED1@31979|Clostridiaceae	186801|Clostridia	C	Dehydrogenase	gldA	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
WZS3_k127_4787595_3	999413.HMPREF1094_01767	1.681e-81	287.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,3VPTR@526524|Erysipelotrichia	526524|Erysipelotrichia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,FtsX
WZS3_k127_4787595_4	999413.HMPREF1094_01767	8.99e-74	273.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,3VPTR@526524|Erysipelotrichia	526524|Erysipelotrichia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,FtsX
WZS3_k127_4787595_6	1237149.C900_04889	7.615e-61	220.0	COG0668@1|root,COG0668@2|Bacteria,4NF28@976|Bacteroidetes,47P8R@768503|Cytophagia	976|Bacteroidetes	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
WZS3_k127_4787595_1	638301.HMPREF0444_1382	5.992e-113	376.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,4HAYA@91061|Bacilli,27FWE@186828|Carnobacteriaceae	91061|Bacilli	H	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
WZS3_k127_4787595_0	536232.CLM_1740	9.259e-146	468.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,36DK2@31979|Clostridiaceae	186801|Clostridia	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
WZS3_k127_4787595_8	546269.HMPREF0389_01123	2.932e-39	148.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25QJW@186804|Peptostreptococcaceae	186801|Clostridia	G	Transketolase	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
WZS3_k127_4794162_1	1211819.CALK01000006_gene2554	6.559e-50	181.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,3VP6Y@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WZS3_k127_4794162_0	650150.ERH_0551	5.874e-139	451.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,3VNZE@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
WZS3_k127_4794162_2	759913.SDSE_0965	5.319e-36	140.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HF9U@91061|Bacilli,1M9E4@119603|Streptococcus dysgalactiae group	1239|Firmicutes	V	ABC-type antimicrobial peptide transport system, permease component	yvrN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
WZS3_k127_4813702_1	1211819.CALK01000028_gene1946	2.162e-143	459.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,3VP7V@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
WZS3_k127_4813702_6	545696.HOLDEFILI_00261	4.936e-24	102.0	COG1278@1|root,COG1278@2|Bacteria,1TU0Y@1239|Firmicutes,3VRJW@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
WZS3_k127_4813702_7	518637.EUBIFOR_01956	3.903e-18	94.0	COG1040@1|root,COG1040@2|Bacteria,1VE65@1239|Firmicutes,3VRS3@526524|Erysipelotrichia	526524|Erysipelotrichia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4813702_2	545696.HOLDEFILI_00258	4.907e-95	323.0	COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,3VNT2@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Helicase C-terminal domain protein	comFA	-	-	ko:K02240	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1	-	-	DEAD,Helicase_C,ResIII
WZS3_k127_4813702_5	1121874.KB892380_gene1569	4.663e-52	190.0	COG0560@1|root,COG0560@2|Bacteria,1V8Y8@1239|Firmicutes,3VQNW@526524|Erysipelotrichia	526524|Erysipelotrichia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
WZS3_k127_4813702_4	1414720.CBYM010000072_gene3357	3.423e-63	230.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,36HCI@31979|Clostridiaceae	186801|Clostridia	T	Signal transduction histidine kinase	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_4813702_3	702450.CUW_2695	3.311e-79	271.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,3VQUZ@526524|Erysipelotrichia	526524|Erysipelotrichia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_4813702_8	105425.BBPL01000054_gene5623	3.449e-07	61.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,2NGQE@228398|Streptacidiphilus	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
WZS3_k127_4813702_0	1232449.BAHV02000010_gene2996	7.437e-217	687.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,2685P@186813|unclassified Clostridiales	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
WZS3_k127_4816116_0	908340.HMPREF9406_0196	1.581e-118	390.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,36EUE@31979|Clostridiaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
WZS3_k127_4816116_1	1121874.KB892379_gene292	1.023e-18	89.0	COG4851@1|root,COG4851@2|Bacteria,1TSYE@1239|Firmicutes,3VPGF@526524|Erysipelotrichia	526524|Erysipelotrichia	S	COG COG4851 Protein involved in sex pheromone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	CamS
WZS3_k127_4831158_4	999413.HMPREF1094_03505	2.219e-74	257.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,3VQ41@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Response regulator receiver domain protein	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_4831158_2	908340.HMPREF9406_1964	9.217e-102	340.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,36UI2@31979|Clostridiaceae	186801|Clostridia	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
WZS3_k127_4831158_7	428127.EUBDOL_01025	4.654e-23	99.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,3VRNC@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
WZS3_k127_4831158_3	1232449.BAHV02000012_gene2340	1.533e-86	291.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,267Y0@186813|unclassified Clostridiales	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
WZS3_k127_4831158_0	545696.HOLDEFILI_03027	9.468e-163	526.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,3VPKH@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS3_k127_4831158_1	552396.HMPREF0863_00981	7.46e-117	389.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,3VNY8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Psort location Cytoplasmic, score 8.87	yqeV	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,UPF0004
WZS3_k127_4831158_6	1121874.KB892377_gene1386	1.884e-30	130.0	2EMKU@1|root,33F98@2|Bacteria,1VPXK@1239|Firmicutes,3VSB4@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4831158_5	428126.CLOSPI_00572	5.793e-51	189.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,3VQY5@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
WZS3_k127_4853689_1	469596.HMPREF9488_03484	2.271e-29	118.0	COG0789@1|root,COG0789@2|Bacteria,1VAAP@1239|Firmicutes,3VR9I@526524|Erysipelotrichia	526524|Erysipelotrichia	K	helix_turn_helix, mercury resistance	adhR	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
WZS3_k127_4853689_2	697303.Thewi_1094	3.571e-16	81.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,42IZ8@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
WZS3_k127_4853689_0	742765.HMPREF9457_01813	9.968e-88	300.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,27WHG@189330|Dorea	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WZS3_k127_4878474_0	1487921.DP68_17840	2.497e-151	489.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,36E39@31979|Clostridiaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WZS3_k127_4878474_2	1232449.BAHV02000021_gene1121	5.223e-100	336.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,267YK@186813|unclassified Clostridiales	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
WZS3_k127_4878474_3	1232449.BAHV02000021_gene1120	1.428e-90	307.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
WZS3_k127_4878474_1	552396.HMPREF0863_02595	1.672e-105	348.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,3VP23@526524|Erysipelotrichia	526524|Erysipelotrichia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
WZS3_k127_4878474_4	1123009.AUID01000011_gene2294	2.153e-24	103.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,26C3U@186813|unclassified Clostridiales	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
WZS3_k127_4897706_0	1211819.CALK01000033_gene1321	5.649e-273	846.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,3VNSP@526524|Erysipelotrichia	526524|Erysipelotrichia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
WZS3_k127_4901739_1	59748.PA0530	9.888e-68	236.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,3WTD9@544448|Tenericutes	544448|Tenericutes	V	Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
WZS3_k127_4901739_0	526218.Sterm_0753	4.377e-80	278.0	COG1957@1|root,COG1957@2|Bacteria,37A7X@32066|Fusobacteria	32066|Fusobacteria	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	-	ko:K01250,ko:K12700	-	-	-	-	ko00000,ko01000	-	-	-	IU_nuc_hydro
WZS3_k127_4901739_2	1123009.AUID01000011_gene2294	2.306e-19	89.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,26C3U@186813|unclassified Clostridiales	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
WZS3_k127_4914812_8	545696.HOLDEFILI_01699	7.864e-10	63.0	2EIBI@1|root,33C2Y@2|Bacteria,1VNGY@1239|Firmicutes,3VS6B@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4914812_2	1211819.CALK01000011_gene2894	9.54e-172	563.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,3VP3S@526524|Erysipelotrichia	526524|Erysipelotrichia	M	penicillin-binding protein	pbpB	-	-	ko:K08724	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PASTA,PBP_dimer,Transpeptidase
WZS3_k127_4914812_4	545696.HOLDEFILI_01704	4.374e-96	323.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,3VNY6@526524|Erysipelotrichia	526524|Erysipelotrichia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
WZS3_k127_4914812_3	1211819.CALK01000011_gene2889	3.639e-135	444.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,3VNZX@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS3_k127_4914812_7	1211819.CALK01000003_gene3093	1.761e-17	85.0	2E9N5@1|root,333UP@2|Bacteria,1VEJZ@1239|Firmicutes,3VRN6@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Post-transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Post_transc_reg
WZS3_k127_4914812_1	1211819.CALK01000003_gene3094	1.471e-279	878.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,3VPUF@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	-	-	-	-	-	-	-	-	-	SecD_SecF,Sec_GG
WZS3_k127_4914812_5	1211819.CALK01000003_gene3095	2.136e-84	299.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,3VP4F@526524|Erysipelotrichia	526524|Erysipelotrichia	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
WZS3_k127_4914812_6	545696.HOLDEFILI_03655	2.843e-82	277.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,3VQAF@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WZS3_k127_4914812_0	1121874.KB892377_gene933	4.498e-312	970.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,3VNQ1@526524|Erysipelotrichia	526524|Erysipelotrichia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
WZS3_k127_4932023_0	37659.JNLN01000001_gene340	1.681e-234	745.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,36DHN@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
WZS3_k127_4932023_4	1541959.KQ51_00617	3.9e-41	159.0	COG2717@1|root,COG2717@2|Bacteria	2|Bacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	yedZ_2	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	FMN_bind,Ferric_reduct,Rieske
WZS3_k127_4932023_5	1121324.CLIT_2c01840	3.047e-19	92.0	COG4892@1|root,COG4892@2|Bacteria,1V64Y@1239|Firmicutes,25DVQ@186801|Clostridia	186801|Clostridia	S	Cytochrome b5-like Heme/Steroid binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cyt-b5
WZS3_k127_4932023_3	994573.T472_0215670	1.386e-41	161.0	COG1633@1|root,COG1633@2|Bacteria,1VAXV@1239|Firmicutes,24KX7@186801|Clostridia,36MJ6@31979|Clostridiaceae	186801|Clostridia	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2202
WZS3_k127_4932023_2	221988.MS0597	1.999e-47	173.0	COG0346@1|root,COG0346@2|Bacteria,1N0VU@1224|Proteobacteria,1S7C0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	bleomycin resistance protein	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
WZS3_k127_4932023_1	931276.Cspa_c29200	3.105e-92	314.0	COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,24MJI@186801|Clostridia,36WRP@31979|Clostridiaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08159,ko:K08164	-	-	-	-	ko00000,ko02000	2.A.1.2,2.A.1.2.15,2.A.1.2.18	-	-	MFS_1,Sugar_tr
WZS3_k127_4932301_1	1286171.EAL2_808p00620	5.376e-42	159.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,25V2C@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	moeB	-	-	-	-	-	-	-	-	-	-	-	ThiF
WZS3_k127_4932301_0	552396.HMPREF0863_00667	1.237e-68	243.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,3VQA5@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_4962827_1	1354300.AUQY01000005_gene315	1.108e-18	86.0	COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24KCI@186801|Clostridia,22HSP@1570339|Peptoniphilaceae	186801|Clostridia	P	Chromate transport protein	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WZS3_k127_4962827_0	1211844.CBLM010000081_gene3371	2.439e-21	101.0	COG1102@1|root,COG1102@2|Bacteria,1VQT0@1239|Firmicutes,3VU6A@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
WZS3_k127_4963121_0	511680.BUTYVIB_00391	1.252e-139	456.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,24A83@186801|Clostridia,4BYZ3@830|Butyrivibrio	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WZS3_k127_4963121_2	552396.HMPREF0863_01372	5.836e-41	161.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,3VQYV@526524|Erysipelotrichia	526524|Erysipelotrichia	P	ABC transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
WZS3_k127_4963121_1	903814.ELI_2275	5.496e-101	336.0	COG1741@1|root,COG1741@2|Bacteria,1TQDV@1239|Firmicutes,2497R@186801|Clostridia,25YAX@186806|Eubacteriaceae	186801|Clostridia	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
WZS3_k127_4981476_1	1211819.CALK01000005_gene2399	3.398e-124	413.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,3VNSJ@526524|Erysipelotrichia	526524|Erysipelotrichia	F	bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain glutamine amidotransferase domain) K01952	-	-	-	-	-	-	-	-	-	-	-	-	AIRS_C,GATase_5
WZS3_k127_4981476_3	702450.CUW_1325	1.638e-101	335.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,3VNVH@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Belongs to the SAICAR synthetase family	purC	-	-	-	-	-	-	-	-	-	-	-	SAICAR_synt
WZS3_k127_4981476_0	702450.CUW_1326	5.635e-189	600.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,3VNQV@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	-	-	-	-	-	-	-	-	-	-	GATase_7,Pribosyltran
WZS3_k127_4981476_2	562982.HMPREF0432_00284	6.111e-120	394.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli,3WEEY@539002|Bacillales incertae sedis	91061|Bacilli	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WZS3_k127_4997831_2	1541960.KQ78_00625	3.669e-28	130.0	COG2207@1|root,COG2207@2|Bacteria,3WURA@544448|Tenericutes	544448|Tenericutes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WZS3_k127_4997831_1	1541960.KQ78_00626	4.798e-85	302.0	COG4753@1|root,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
WZS3_k127_4997831_0	1449338.JQLU01000005_gene1931	1.846e-85	292.0	COG2253@1|root,COG2253@2|Bacteria,1TQ54@1239|Firmicutes,4HJ2Q@91061|Bacilli	91061|Bacilli	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
WZS3_k127_4997831_3	1449338.JQLU01000005_gene1932	1.655e-26	111.0	COG5340@1|root,COG5340@2|Bacteria,1V3P6@1239|Firmicutes,4HW2V@91061|Bacilli	91061|Bacilli	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4998007_4	888064.HMPREF9088_1331	3.934e-22	99.0	COG1733@1|root,COG1733@2|Bacteria,1VBI7@1239|Firmicutes,4HKBR@91061|Bacilli,4B3CX@81852|Enterococcaceae	91061|Bacilli	K	HxlR-like helix-turn-helix	yodB	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	HxlR
WZS3_k127_4998007_1	650150.ERH_0379	1.841e-49	182.0	2E11M@1|root,32WHH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_4998007_5	1499967.BAYZ01000048_gene2701	2.034e-12	71.0	2DMDR@1|root,32QSY@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1475)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1475
WZS3_k127_4998007_2	552398.HMPREF0866_01434	1.078e-43	161.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3WJX0@541000|Ruminococcaceae	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WZS3_k127_4998007_0	469596.HMPREF9488_02174	3.768e-73	255.0	COG1307@1|root,COG1307@2|Bacteria,1TXFX@1239|Firmicutes,3VNS9@526524|Erysipelotrichia	526524|Erysipelotrichia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
WZS3_k127_4998007_3	871968.DESME_05400	1.804e-26	113.0	2AJWE@1|root,31AJA@2|Bacteria,1VATY@1239|Firmicutes,24MXD@186801|Clostridia,265CR@186807|Peptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_501530_5	545696.HOLDEFILI_01710	1.638e-27	115.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,3VPY6@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_501530_0	1232449.BAHV02000010_gene2616	0.0	1695.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
WZS3_k127_501530_3	1232449.BAHV02000010_gene2668	8.35e-135	436.0	COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,249NS@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	2.4.1.208	ko:K13677	ko00561,ko01100,map00561,map01100	-	R05164	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
WZS3_k127_501530_1	545696.HOLDEFILI_01715	6.141e-201	646.0	COG0438@1|root,COG2137@1|root,COG0438@2|Bacteria,COG2137@2|Bacteria,1TPTA@1239|Firmicutes,3VPEK@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Modulates RecA activity	recX	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1,RecX
WZS3_k127_501530_4	1232449.BAHV02000010_gene2671	1.189e-99	334.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia	186801|Clostridia	S	domain protein	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
WZS3_k127_501530_6	573061.Clocel_3457	1.179e-16	81.0	COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,24RMA@186801|Clostridia,36P1S@31979|Clostridiaceae	186801|Clostridia	P	Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
WZS3_k127_501530_2	350688.Clos_0054	4.94e-186	596.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,36DJE@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_5037925_1	999413.HMPREF1094_03735	2.539e-101	336.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
WZS3_k127_5037925_0	908340.HMPREF9406_3617	7.009e-115	375.0	COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,24AZD@186801|Clostridia,36FB4@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
WZS3_k127_5039668_1	545696.HOLDEFILI_01074	4.02e-108	353.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,3VPC8@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
WZS3_k127_5039668_3	428126.CLOSPI_02202	1.377e-32	128.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,3VRD6@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
WZS3_k127_5039668_2	545696.HOLDEFILI_01019	1.58e-97	321.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,3VPB4@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Psort location Cytoplasmic, score 8.87	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
WZS3_k127_5039668_0	545696.HOLDEFILI_01017	1.275e-161	515.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,3VP0P@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WZS3_k127_5039668_4	1410674.JNKU01000010_gene1714	5.264e-21	97.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli,3F460@33958|Lactobacillaceae	91061|Bacilli	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
WZS3_k127_5044804_0	332101.JIBU02000043_gene1519	2.878e-128	414.0	COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,247J8@186801|Clostridia,36F77@31979|Clostridiaceae	186801|Clostridia	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
WZS3_k127_5044804_1	445335.CBN_1239	3.588e-91	308.0	COG0524@1|root,COG1846@1|root,COG0524@2|Bacteria,COG1846@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,36F1Z@31979|Clostridiaceae	186801|Clostridia	G	hmm pf00294	rbsK	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
WZS3_k127_5054877_18	1121874.KB892380_gene1507	4.046e-05	47.0	COG1597@1|root,COG1597@2|Bacteria,1V1DP@1239|Firmicutes,3VQKD@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WZS3_k127_5054877_9	1211819.CALK01000015_gene1216	4.236e-70	246.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,3VPQC@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
WZS3_k127_5054877_6	1410658.JHWI01000015_gene1680	3.045e-83	286.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,3VP5H@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	-	-	-	-	-	-	-	-	-	-	Glucosamine_iso
WZS3_k127_5054877_12	552396.HMPREF0863_02186	3.527e-32	136.0	COG0561@1|root,COG0561@2|Bacteria,1UZF9@1239|Firmicutes,3VQ4X@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_5054877_13	1121874.KB892380_gene1506	5.3e-31	124.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,3VR6N@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
WZS3_k127_5054877_8	1232449.BAHV02000011_gene2169	1.512e-74	254.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia	186801|Clostridia	K	domain protein	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
WZS3_k127_5054877_0	1121874.KB892380_gene1504	2.251e-169	538.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,3VNWE@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
WZS3_k127_5054877_3	1121874.KB892380_gene1503	3.21e-116	381.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,3VNUQ@526524|Erysipelotrichia	526524|Erysipelotrichia	P	ABC transporter, permease protein	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
WZS3_k127_5054877_5	552396.HMPREF0863_01360	8.008e-99	329.0	COG0687@1|root,COG1177@1|root,COG0687@2|Bacteria,COG1177@2|Bacteria,1TPY1@1239|Firmicutes,3VNQU@526524|Erysipelotrichia	526524|Erysipelotrichia	P	ABC transporter, solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
WZS3_k127_5054877_2	1232449.BAHV02000011_gene2173	1.516e-124	407.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,268BB@186813|unclassified Clostridiales	186801|Clostridia	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
WZS3_k127_5054877_4	650150.ERH_1495	1.354e-109	364.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,3VNQU@526524|Erysipelotrichia	526524|Erysipelotrichia	P	ABC transporter, solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
WZS3_k127_5054877_15	1121091.AUMP01000054_gene3367	3.855e-09	59.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5054877_11	445971.ANASTE_01641	2.15e-40	158.0	2EAX3@1|root,32WEX@2|Bacteria,1UPRN@1239|Firmicutes,24Q86@186801|Clostridia	186801|Clostridia	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
WZS3_k127_5054877_10	1121333.JMLH01000030_gene1323	3.475e-49	186.0	COG0613@1|root,COG0613@2|Bacteria,1TP95@1239|Firmicutes,3VP7X@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PHP
WZS3_k127_5054877_1	552396.HMPREF0863_02454	3.803e-150	486.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,3VNYK@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,TRAM,UPF0004
WZS3_k127_5054877_14	1304284.L21TH_2309	9.322e-11	67.0	COG2172@1|root,COG2172@2|Bacteria,1VFTW@1239|Firmicutes,24RBU@186801|Clostridia,36MVU@31979|Clostridiaceae	186801|Clostridia	T	sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5054877_7	357809.Cphy_1504	1.349e-77	275.0	2DB7K@1|root,2Z7MK@2|Bacteria,1TQ79@1239|Firmicutes,2489P@186801|Clostridia,21YG7@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function (DUF1576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1576
WZS3_k127_5061705_0	293826.Amet_4520	2.101e-221	692.0	COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes,24C4U@186801|Clostridia,36G9Z@31979|Clostridiaceae	186801|Clostridia	F	TIGRFAM ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC
WZS3_k127_5104831_2	877415.JNJQ01000001_gene1941	1.17e-14	75.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,3VPQC@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Aldose 1-epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
WZS3_k127_5104831_0	755731.Clo1100_0058	1.273e-69	246.0	COG1597@1|root,COG1597@2|Bacteria,1V1DP@1239|Firmicutes,25CN2@186801|Clostridia,36HD9@31979|Clostridiaceae	186801|Clostridia	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
WZS3_k127_5104831_1	1211819.CALK01000015_gene1219	5.845e-39	149.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,3VPMY@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
WZS3_k127_5109787_3	1211819.CALK01000032_gene3005	1.825e-67	233.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,3VQ89@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
WZS3_k127_5109787_1	1211819.CALK01000025_gene3167	2.687e-107	352.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,3VNQD@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Psort location CytoplasmicMembrane, score 9.49	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
WZS3_k127_5109787_2	545696.HOLDEFILI_00305	2.807e-89	311.0	COG4942@1|root,COG4942@2|Bacteria,1V5F4@1239|Firmicutes,3VQ4N@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WZS3_k127_5109787_0	1123263.AUKY01000047_gene26	1.472e-115	389.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,3VPKZ@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,PG_binding_1,Peptidase_S41
WZS3_k127_5109787_4	1410674.JNKU01000035_gene415	2.356e-07	53.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli,3F3XM@33958|Lactobacillaceae	91061|Bacilli	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
WZS3_k127_5113102_2	1123313.ATUT01000010_gene1593	4.422e-39	147.0	COG0745@1|root,COG0745@2|Bacteria,1TR8K@1239|Firmicutes,3VNRV@526524|Erysipelotrichia	526524|Erysipelotrichia	T	Response regulator receiver domain protein	cssR	-	-	ko:K07770	ko02020,map02020	M00448	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_5113102_0	1121874.KB892379_gene44	1.478e-120	401.0	COG0642@1|root,COG0642@2|Bacteria,1UJ2Z@1239|Firmicutes,3VNSX@526524|Erysipelotrichia	526524|Erysipelotrichia	T	sensor histidine kinase	-	-	2.7.13.3	ko:K07650	ko02020,map02020	M00448	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
WZS3_k127_5113102_1	1123263.AUKY01000020_gene1117	5.397e-72	250.0	COG0596@1|root,COG0596@2|Bacteria,1VRHA@1239|Firmicutes,3VPR3@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
WZS3_k127_5113102_3	545696.HOLDEFILI_03796	2.53e-32	134.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,3VNW7@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Mur ligase family, glutamate ligase domain	murF	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS3_k127_5143762_3	1462526.BN990_03836	0.0002496	43.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,4C5SX@84406|Virgibacillus	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WZS3_k127_5143762_2	720554.Clocl_3981	1.524e-67	233.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3WHD9@541000|Ruminococcaceae	186801|Clostridia	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
WZS3_k127_5143762_0	221027.JO40_01045	4.453e-80	275.0	COG0489@1|root,COG0489@2|Bacteria,2J573@203691|Spirochaetes	203691|Spirochaetes	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	-	-	-	-	-	-	-	-	-	ParA
WZS3_k127_5143762_1	1211844.CBLM010000028_gene1907	1.384e-77	262.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,3VPFG@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Psort location CytoplasmicMembrane, score 10.00	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
WZS3_k127_5149468_1	1089546.AQUI01000002_gene3205	3.354e-05	53.0	COG0207@1|root,COG0207@2|Bacteria,2GKY0@201174|Actinobacteria,409YI@622450|Actinopolysporales	201174|Actinobacteria	F	Thymidylate synthase	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
WZS3_k127_5149468_0	1121289.JHVL01000033_gene2679	1.044e-11	67.0	COG2199@1|root,COG3706@2|Bacteria,1V2AM@1239|Firmicutes,25EYJ@186801|Clostridia,36USX@31979|Clostridiaceae	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HisKA_7TM,PAS_9
WZS3_k127_515426_0	650150.ERH_1334	6.459e-231	719.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,3VNTC@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
WZS3_k127_515426_5	1121874.KB892378_gene676	6.26e-112	365.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,3VPAP@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
WZS3_k127_515426_1	545696.HOLDEFILI_00397	1.687e-183	581.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,3VNTX@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Psort location Cytoplasmic, score	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
WZS3_k127_515426_2	1123309.AQYB01000033_gene1107	3.148e-152	495.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli	91061|Bacilli	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
WZS3_k127_515426_4	545696.HOLDEFILI_00395	1.816e-126	414.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,3VP1A@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	-	-	-	-	-	-	-	-	-	-	Hexapep,NTP_transferase
WZS3_k127_515426_3	1123309.AQYB01000033_gene1109	1.681e-151	487.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli	91061|Bacilli	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
WZS3_k127_515426_9	445974.CLORAM_01295	5.473e-36	147.0	296F1@1|root,2ZTQN@2|Bacteria,1V2X0@1239|Firmicutes,3VQF4@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_515426_6	1232449.BAHV02000008_gene578	2.019e-109	368.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,267KT@186813|unclassified Clostridiales	186801|Clostridia	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS3_k127_515426_8	658088.HMPREF0987_02424	1.463e-84	285.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,27IMS@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
WZS3_k127_515426_7	1211819.CALK01000022_gene1658	6.674e-106	357.0	COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes	1239|Firmicutes	EGP	Major facilitator superfamily	yqgE	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
WZS3_k127_515426_10	1121874.KB892380_gene1529	5.533e-28	124.0	COG1653@1|root,COG1653@2|Bacteria,1VNZ7@1239|Firmicutes,3VSA1@526524|Erysipelotrichia	526524|Erysipelotrichia	G	transport	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	-
WZS3_k127_5160559_2	406124.ACPC01000022_gene4115	3.038e-131	428.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,1ZC6M@1386|Bacillus	91061|Bacilli	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WZS3_k127_5160559_3	646529.Desaci_1686	1.023e-49	183.0	COG0778@1|root,COG0778@2|Bacteria,1V49Q@1239|Firmicutes,24IH8@186801|Clostridia	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WZS3_k127_5160559_0	1121289.JHVL01000062_gene258	3.282e-187	592.0	COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,2491D@186801|Clostridia,36DZ7@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	kbl	GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS3_k127_5160559_1	986075.CathTA2_2562	7.867e-136	440.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HD08@91061|Bacilli	91061|Bacilli	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
WZS3_k127_5160559_5	1117379.BABA_02442	3.898e-13	74.0	2CTED@1|root,32ST9@2|Bacteria,1VD31@1239|Firmicutes,4IIME@91061|Bacilli,1ZGY7@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5160559_4	1286171.EAL2_808p00620	5.169e-48	178.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,25V2C@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	moeB	-	-	-	-	-	-	-	-	-	-	-	ThiF
WZS3_k127_5169995_1	1031288.AXAA01000030_gene245	1.143e-51	192.0	COG0366@1|root,COG0366@2|Bacteria,1U7JS@1239|Firmicutes,24ATB@186801|Clostridia,36HBW@31979|Clostridiaceae	186801|Clostridia	G	Glycogen debranching enzyme, glucanotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
WZS3_k127_5169995_0	794903.OPIT5_11470	6.683e-62	218.0	COG2865@1|root,COG2865@2|Bacteria,46W8I@74201|Verrucomicrobia,3K9Y3@414999|Opitutae	414999|Opitutae	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
WZS3_k127_5171570_1	545696.HOLDEFILI_01984	4.39e-62	215.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,3VQ7U@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
WZS3_k127_5171570_0	1211819.CALK01000008_gene2682	3.137e-63	232.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,3VRDY@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
WZS3_k127_5171570_2	1235796.C815_01267	1.203e-08	56.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes	1239|Firmicutes	J	Responsible for synthesis of pseudouridine from uracil	rluD	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_5216732_0	545696.HOLDEFILI_03145	8.078e-111	364.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,3VP9S@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
WZS3_k127_5216732_2	552396.HMPREF0863_00923	6.384e-30	121.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,3VRR0@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
WZS3_k127_5216732_1	1211819.CALK01000007_gene2588	1.781e-65	230.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,3VPV2@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
WZS3_k127_5216732_3	1232449.BAHV02000012_gene2285	9.839e-06	52.0	COG3227@1|root,COG3227@2|Bacteria,1W4FI@1239|Firmicutes	1239|Firmicutes	E	Domain of unknown function (DUF5011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011
WZS3_k127_5222000_5	411490.ANACAC_00564	2.679e-48	184.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia	186801|Clostridia	GKT	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
WZS3_k127_5222000_7	1120746.CCNL01000017_gene3160	2.771e-30	121.0	COG2213@1|root,COG2213@2|Bacteria,2NQ97@2323|unclassified Bacteria	2|Bacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
WZS3_k127_5222000_2	1118054.CAGW01000025_gene537	8.901e-144	464.0	COG2213@1|root,COG2213@2|Bacteria,1TPE3@1239|Firmicutes,4HAVV@91061|Bacilli,26UDH@186822|Paenibacillaceae	91061|Bacilli	G	CmtA with CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli	mtlA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
WZS3_k127_5222000_8	762211.BSTEL_1237	5.358e-07	58.0	COG4715@1|root,COG4715@2|Bacteria	2|Bacteria	S	zinc ion binding	CP_1020	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
WZS3_k127_5222000_4	827.JFJK01000008_gene1641	1.002e-58	206.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2YTJ1@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
WZS3_k127_5222000_0	1209989.TepiRe1_0283	0.0	1034.0	COG0425@1|root,COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0425@2|Bacteria,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,42EW6@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
WZS3_k127_5222000_9	469596.HMPREF9488_02708	0.0004651	51.0	COG0758@1|root,COG0758@2|Bacteria,1UZAS@1239|Firmicutes,3VPM9@526524|Erysipelotrichia	526524|Erysipelotrichia	LU	DNA recombination-mediator protein A	-	-	-	-	-	-	-	-	-	-	-	-	DNA_processg_A
WZS3_k127_5222000_3	1410668.JNKC01000001_gene1178	6.287e-79	274.0	COG2378@1|root,COG2378@2|Bacteria,1TSA2@1239|Firmicutes,247S2@186801|Clostridia,36HK4@31979|Clostridiaceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
WZS3_k127_5222000_6	1294142.CINTURNW_2598	1.273e-30	129.0	COG2364@1|root,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,24AJQ@186801|Clostridia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5222000_1	1449336.JQLO01000001_gene974	2.387e-155	501.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli,27FN5@186828|Carnobacteriaceae	91061|Bacilli	E	Cleaves the N-terminal amino acid of tripeptides	pepT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
WZS3_k127_5237315_0	545696.HOLDEFILI_02623	5.252e-129	423.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,3VP0B@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Peptidase, U32 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32,Peptidase_U32_C
WZS3_k127_5237315_1	518637.EUBIFOR_01412	1.134e-33	135.0	COG0566@1|root,COG0566@2|Bacteria,1V1NM@1239|Firmicutes,3VQ8P@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase,SpoU_sub_bind
WZS3_k127_5251607_0	518637.EUBIFOR_02550	3.73e-80	284.0	COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,3VNUD@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Transposase, IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
WZS3_k127_5251607_1	469616.FMAG_02254	5.111e-09	62.0	COG0531@1|root,COG0531@2|Bacteria,379SQ@32066|Fusobacteria	32066|Fusobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
WZS3_k127_5255261_5	523791.Kkor_0119	1.333e-16	83.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,1RR6R@1236|Gammaproteobacteria,1XKBN@135619|Oceanospirillales	135619|Oceanospirillales	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
WZS3_k127_5255261_4	1196323.ALKF01000203_gene3820	2.18e-27	115.0	COG2764@1|root,COG2764@2|Bacteria,1V3WE@1239|Firmicutes,4HHHS@91061|Bacilli,26XJK@186822|Paenibacillaceae	91061|Bacilli	S	Glyoxalase	phnB7	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
WZS3_k127_5255261_1	1507.HMPREF0262_03551	1.343e-101	339.0	COG1957@1|root,COG1957@2|Bacteria,1TQUN@1239|Firmicutes,25C8X@186801|Clostridia,36WRS@31979|Clostridiaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 7.50	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
WZS3_k127_5255261_2	1163671.JAGI01000002_gene3386	3.724e-62	227.0	COG1957@1|root,COG1957@2|Bacteria,1TQUN@1239|Firmicutes,25C8X@186801|Clostridia,36WRS@31979|Clostridiaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 7.50	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
WZS3_k127_5255261_0	994573.T472_0201930	1.345e-129	419.0	COG0622@1|root,COG0622@2|Bacteria,1UIW3@1239|Firmicutes,25EZ0@186801|Clostridia,36UTA@31979|Clostridiaceae	186801|Clostridia	S	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
WZS3_k127_5255261_3	1120998.AUFC01000001_gene1960	8.364e-39	150.0	COG1237@1|root,COG1237@2|Bacteria,1UWI6@1239|Firmicutes,247K3@186801|Clostridia	186801|Clostridia	S	beta-lactamase superfamily II	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
WZS3_k127_5256983_1	1033810.HLPCO_003133	8.627e-28	117.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	yjhB	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX,Nudix_N
WZS3_k127_5256983_0	1211819.CALK01000017_gene509	6.689e-69	239.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,3VNW7@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Mur ligase family, glutamate ligase domain	murF	-	-	-	-	-	-	-	-	-	-	-	Mur_ligase_C,Mur_ligase_M
WZS3_k127_5267231_4	1050201.KB913034_gene838	1.822e-18	85.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,3VQE1@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
WZS3_k127_5267231_2	658659.HMPREF0983_02089	5.37e-89	302.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,3VPRA@526524|Erysipelotrichia	526524|Erysipelotrichia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
WZS3_k127_5267231_0	1211819.CALK01000009_gene2847	4.356e-163	529.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,3VP78@526524|Erysipelotrichia	526524|Erysipelotrichia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
WZS3_k127_5267231_3	1123405.AUMM01000002_gene352	1.648e-47	179.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,26NS3@186821|Sporolactobacillaceae	91061|Bacilli	T	Protein phosphatase 2C	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
WZS3_k127_5267231_1	1232449.BAHV02000010_gene2856	7.391e-151	483.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,267KN@186813|unclassified Clostridiales	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192,2.1.1.224	ko:K06941,ko:K15632	-	-	-	-	ko00000,ko01000,ko01504,ko03009	-	-	-	Fer4_14,Radical_SAM
WZS3_k127_5323157_1	1541960.KQ78_00623	1.611e-54	198.0	COG1879@1|root,COG1879@2|Bacteria,3WUR4@544448|Tenericutes	544448|Tenericutes	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
WZS3_k127_5323157_0	1541960.KQ78_00624	6.801e-136	454.0	COG2972@1|root,COG2972@2|Bacteria,3WUD4@544448|Tenericutes	544448|Tenericutes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase,dCache_1
WZS3_k127_5323157_2	1541960.KQ78_00625	1.271e-14	74.0	COG2207@1|root,COG2207@2|Bacteria,3WURA@544448|Tenericutes	544448|Tenericutes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
WZS3_k127_5337538_10	866775.HMPREF9243_1991	9.899e-13	68.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli,27DIF@186827|Aerococcaceae	91061|Bacilli	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
WZS3_k127_5337538_9	545696.HOLDEFILI_01306	8.906e-30	118.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,3VRMZ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
WZS3_k127_5337538_2	1236973.JCM9157_3505	2.964e-97	325.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli,1ZC9G@1386|Bacillus	91061|Bacilli	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
WZS3_k127_5337538_7	1235796.C815_00305	4.093e-43	161.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes	1239|Firmicutes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
WZS3_k127_5337538_1	908340.HMPREF9406_4219	2.091e-132	435.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,36EXD@31979|Clostridiaceae	186801|Clostridia	L	AAA ATPase	yrvN	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
WZS3_k127_5337538_6	1211819.CALK01000047_gene1771	5.881e-45	177.0	28JX7@1|root,2Z9MQ@2|Bacteria,1UZRY@1239|Firmicutes,3VQGJ@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5337538_8	1232449.BAHV02000002_gene173	1.823e-35	149.0	COG1668@1|root,COG1668@2|Bacteria,1VVHB@1239|Firmicutes	1239|Firmicutes	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
WZS3_k127_5337538_5	1232449.BAHV02000002_gene172	7.414e-51	191.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,249YC@186801|Clostridia	186801|Clostridia	S	Abc transporter	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
WZS3_k127_5337538_4	1111732.AZOD01000017_gene359	1.422e-62	218.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,1S228@1236|Gammaproteobacteria,1X4NN@135614|Xanthomonadales	135614|Xanthomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
WZS3_k127_5337538_3	1235796.C815_01722	2.323e-88	300.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes	1239|Firmicutes	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
WZS3_k127_5337538_0	1211819.CALK01000046_gene1746	1.507e-150	495.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,3VNQG@526524|Erysipelotrichia	526524|Erysipelotrichia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
WZS3_k127_5339422_0	1211819.CALK01000020_gene874	1.055e-71	249.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,3VPQY@526524|Erysipelotrichia	526524|Erysipelotrichia	NU	type II secretion pathway protein E K01509	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
WZS3_k127_5382477_4	545693.BMQ_4441	4.722e-07	51.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,4H9QV@91061|Bacilli,1ZC7E@1386|Bacillus	91061|Bacilli	C	Belongs to the acetokinase family	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
WZS3_k127_5382477_0	1033810.HLPCO_002285	5.2e-135	439.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
WZS3_k127_5382477_2	469618.FVAG_01648	3.031e-28	122.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	traL	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	CbiA
WZS3_k127_5382477_3	1301100.HG529419_gene3059	1.617e-25	107.0	COG1143@1|root,COG1143@2|Bacteria,1UHZA@1239|Firmicutes,24QVY@186801|Clostridia,36UN5@31979|Clostridiaceae	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
WZS3_k127_5382477_1	1499967.BAYZ01000147_gene703	9.236e-106	351.0	COG0674@1|root,COG0674@2|Bacteria,2NNWT@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	porA6	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
WZS3_k127_5392184_1	572544.Ilyop_1566	2.468e-73	250.0	COG1592@1|root,COG1592@2|Bacteria,37A01@32066|Fusobacteria	32066|Fusobacteria	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
WZS3_k127_5392184_0	445974.CLORAM_00612	5.154e-77	263.0	COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,3VPPY@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
WZS3_k127_5393601_10	1541959.KQ51_00511	8.801e-10	60.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
WZS3_k127_5393601_7	562743.JH976434_gene1834	1.357e-35	142.0	2EGE1@1|root,33A5Y@2|Bacteria,1VV4C@1239|Firmicutes,4HVGE@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5393601_5	545696.HOLDEFILI_00861	2.33e-53	198.0	COG3584@1|root,COG3584@2|Bacteria,1VB9X@1239|Firmicutes,3VRGX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
WZS3_k127_5393601_8	315749.Bcer98_0035	1.1e-33	136.0	COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli,1ZFNN@1386|Bacillus	91061|Bacilli	J	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step	rnmV	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.8	ko:K05985	-	-	-	-	ko00000,ko01000	-	-	-	DUF4093,Toprim,Toprim_4
WZS3_k127_5393601_3	1121936.AUHI01000012_gene1249	5.367e-57	208.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
WZS3_k127_5393601_2	1504823.CCMM01000012_gene2120	1.185e-78	271.0	COG1947@1|root,COG1947@2|Bacteria,2NPGM@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	2.1.1.182,2.7.1.148	ko:K00919,ko:K02528,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634,R10716	RC00002,RC00003,RC01439,RC03257	ko00000,ko00001,ko00002,ko01000,ko02000,ko03009	3.A.1.29	-	iEC55989_1330.EC55989_1304,iLJ478.TM1383,iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
WZS3_k127_5393601_9	1280679.ATVX01000005_gene975	3.818e-23	99.0	2CDFN@1|root,33CYY@2|Bacteria,1VEJK@1239|Firmicutes,24RI3@186801|Clostridia,4C0BS@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5393601_4	908612.HMPREF9720_2621	1.291e-54	194.0	COG0346@1|root,COG0346@2|Bacteria,4PAXH@976|Bacteroidetes,2FXZN@200643|Bacteroidia	976|Bacteroidetes	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
WZS3_k127_5393601_6	1519439.JPJG01000078_gene912	2.253e-40	152.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,2N7HE@216572|Oscillospiraceae	186801|Clostridia	P	ArsC family	arsC	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
WZS3_k127_5393601_0	545696.HOLDEFILI_00850	2.812e-179	572.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,3VP42@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
WZS3_k127_5393601_1	1121874.KB892380_gene1670	1.542e-118	384.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,3VP98@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WZS3_k127_5402102_2	742733.HMPREF9469_03889	9.718e-17	83.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,24ECW@186801|Clostridia,21ZFE@1506553|Lachnoclostridium	186801|Clostridia	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
WZS3_k127_5402102_1	1235835.C814_03252	1.032e-89	307.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia,3WI89@541000|Ruminococcaceae	186801|Clostridia	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
WZS3_k127_5402102_0	411902.CLOBOL_04546	8.68e-121	394.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia,21Z0F@1506553|Lachnoclostridium	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
WZS3_k127_5404809_1	518637.EUBIFOR_02241	1.907e-24	104.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,3VPD3@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
WZS3_k127_5404809_0	1487923.DP73_13755	3.504e-149	479.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,260S3@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
WZS3_k127_5434075_3	386415.NT01CX_0715	3.764e-44	168.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,36DJS@31979|Clostridiaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
WZS3_k127_5434075_0	1408422.JHYF01000014_gene147	2.318e-129	424.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,36E7D@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
WZS3_k127_5434075_4	552398.HMPREF0866_00654	2.704e-35	140.0	COG2267@1|root,COG2267@2|Bacteria,1V3S1@1239|Firmicutes,24GGH@186801|Clostridia,3WIHR@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
WZS3_k127_5434075_6	1449050.JNLE01000003_gene3254	6.523e-10	62.0	COG2267@1|root,COG2267@2|Bacteria,1V3S1@1239|Firmicutes,24GGH@186801|Clostridia,36V0N@31979|Clostridiaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_5
WZS3_k127_5434075_2	1163671.JAGI01000003_gene770	1.632e-53	192.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,36IXW@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the glutathione peroxidase family	gpxA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
WZS3_k127_5434075_1	1211819.CALK01000021_gene727	5.642e-107	359.0	COG0444@1|root,COG0444@2|Bacteria,1TS8Q@1239|Firmicutes,3VP9N@526524|Erysipelotrichia	526524|Erysipelotrichia	EP	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5480547_1	537013.CLOSTMETH_02228	7.868e-102	337.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3WGUC@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
WZS3_k127_5480547_4	58344.JOEL01000044_gene886	2.095e-06	50.0	COG2267@1|root,COG2267@2|Bacteria,2GPA8@201174|Actinobacteria	201174|Actinobacteria	I	hydrolase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
WZS3_k127_5480547_5	1396.DJ87_3626	0.0006055	49.0	29S0X@1|root,30D59@2|Bacteria,1UAV8@1239|Firmicutes,4IM82@91061|Bacilli,1ZJFX@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5480547_0	642492.Clole_0470	3.612e-119	394.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia	186801|Clostridia	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
WZS3_k127_5480547_2	1502852.FG94_00472	5.326e-39	149.0	COG3607@1|root,COG3607@2|Bacteria,1RH1T@1224|Proteobacteria,2VSCM@28216|Betaproteobacteria,477NV@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
WZS3_k127_5480547_3	632245.CLP_1265	9.772e-22	97.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_5488387_2	1123313.ATUT01000008_gene1768	6.298e-46	171.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,3VNS5@526524|Erysipelotrichia	526524|Erysipelotrichia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
WZS3_k127_5488387_5	650150.ERH_1098	1.766e-37	151.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,3VQAE@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
WZS3_k127_5488387_3	1211819.CALK01000008_gene2672	1.18e-42	161.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,3VR64@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
WZS3_k127_5488387_4	1410668.JNKC01000001_gene2017	3.411e-42	158.0	2E12M@1|root,32WIA@2|Bacteria,1VD2B@1239|Firmicutes,24NKB@186801|Clostridia,36M1W@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5488387_6	428126.CLOSPI_00901	8.559e-12	74.0	COG0457@1|root,COG0457@2|Bacteria	428126.CLOSPI_00901|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5488387_0	1211819.CALK01000008_gene2670	7.598e-138	450.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,3VNR3@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
WZS3_k127_5488387_1	545696.HOLDEFILI_02001	9.46e-66	229.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,3VPIW@526524|Erysipelotrichia	526524|Erysipelotrichia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
WZS3_k127_5492844_2	59748.PA0530	2.087e-12	77.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,3WTD9@544448|Tenericutes	544448|Tenericutes	V	Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
WZS3_k127_5492844_0	908340.HMPREF9406_2498	1.726e-73	272.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,36DXW@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	macB3	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,FtsX,MacB_PCD
WZS3_k127_5492844_1	1051501.AYTL01000027_gene739	9.194e-40	151.0	COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,1ZGG6@1386|Bacillus	91061|Bacilli	J	Alanine acetyltransferase	yjcK	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WZS3_k127_5512852_3	537007.BLAHAN_06460	2.671e-89	301.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XZ6G@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
WZS3_k127_5512852_2	1211819.CALK01000033_gene1391	2.333e-105	349.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,3VP71@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
WZS3_k127_5512852_1	679192.HMPREF9013_1162	4.957e-110	365.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,3VNVF@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
WZS3_k127_5512852_0	1211819.CALK01000033_gene1389	4.478e-111	366.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,3VPI0@526524|Erysipelotrichia	526524|Erysipelotrichia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
WZS3_k127_5530919_5	1211844.CBLM010000083_gene1168	7.412e-09	60.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,3VQ4Q@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Belongs to the sigma-70 factor family	sigF	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS3_k127_5530919_1	428126.CLOSPI_01671	1.215e-67	237.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,3VPEN@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
WZS3_k127_5530919_2	650150.ERH_1532	8.497e-34	134.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,3VQT7@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
WZS3_k127_5530919_0	1232449.BAHV02000001_gene281	1.908e-167	537.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,2684B@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
WZS3_k127_5530919_3	1294142.CINTURNW_4310	8.03e-25	108.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia,36M0N@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5530919_4	1410631.JHWZ01000001_gene932	3.145e-20	91.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,27IJN@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WZS3_k127_5537305_0	1469948.JPNB01000002_gene2896	3.545e-108	360.0	COG4211@1|root,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia,36UND@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	mglC	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
WZS3_k127_5537305_1	1469948.JPNB01000002_gene3337	7.814e-61	217.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,36F2U@31979|Clostridiaceae	186801|Clostridia	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_5551703_0	1121874.KB892377_gene900	1.918e-84	284.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,3VP26@526524|Erysipelotrichia	526524|Erysipelotrichia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
WZS3_k127_5551703_1	1211819.CALK01000004_gene2308	1.806e-38	147.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,3VQEP@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_5567449_0	1347086.CCBA010000015_gene643	3.088e-54	201.0	COG0624@1|root,COG0624@2|Bacteria,1TRHJ@1239|Firmicutes,4I4CJ@91061|Bacilli,1ZEF4@1386|Bacillus	91061|Bacilli	E	Peptidase family M20/M25/M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
WZS3_k127_5567449_1	1034347.CAHJ01000084_gene1343	1.295e-11	77.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli,1ZQ0I@1386|Bacillus	91061|Bacilli	GKT	Mga helix-turn-helix domain	licR	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
WZS3_k127_5582340_5	1499689.CCNN01000007_gene1163	9.313e-59	207.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,36DD8@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
WZS3_k127_5582340_0	572544.Ilyop_1582	3.646e-131	433.0	COG1053@1|root,COG1053@2|Bacteria,379QD@32066|Fusobacteria	32066|Fusobacteria	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
WZS3_k127_5582340_1	1123009.AUID01000021_gene1277	9.359e-89	299.0	COG3279@1|root,COG3279@2|Bacteria,1V9AE@1239|Firmicutes,25KUZ@186801|Clostridia,26BRK@186813|unclassified Clostridiales	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
WZS3_k127_5582340_2	1123009.AUID01000021_gene1276	4.944e-68	248.0	COG3290@1|root,COG3290@2|Bacteria,1VE1S@1239|Firmicutes,24MRT@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
WZS3_k127_5582340_4	656519.Halsa_1177	1.384e-60	216.0	2AVV0@1|root,31215@2|Bacteria,1V4K5@1239|Firmicutes,251D8@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159
WZS3_k127_5582340_3	1348908.KI518642_gene207	7.597e-64	223.0	COG0503@1|root,COG0503@2|Bacteria,1V1XS@1239|Firmicutes,4HG1T@91061|Bacilli,1ZG3Y@1386|Bacillus	91061|Bacilli	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
WZS3_k127_5582340_6	1392491.JIAE01000001_gene234	1.224e-47	175.0	COG1476@1|root,COG1476@2|Bacteria,1V8FS@1239|Firmicutes,24IDH@186801|Clostridia,3WJAF@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
WZS3_k127_5582340_9	1123009.AUID01000011_gene2277	3.467e-13	74.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5582340_7	1487923.DP73_04060	9.784e-30	122.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,265DR@186807|Peptococcaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WZS3_k127_5582340_8	756499.Desde_2820	1.779e-20	101.0	COG0772@1|root,COG0772@2|Bacteria,1V56R@1239|Firmicutes,24I8Y@186801|Clostridia,264DQ@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5588317_6	658086.HMPREF0994_00521	4.737e-10	64.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,24ECW@186801|Clostridia,27IBH@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
WZS3_k127_5588317_3	1408437.JNJN01000002_gene1488	2e-22	100.0	COG1987@1|root,COG1987@2|Bacteria,1U4A9@1239|Firmicutes,25955@186801|Clostridia,25XU9@186806|Eubacteriaceae	186801|Clostridia	NU	Bacterial export proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	Bac_export_3
WZS3_k127_5588317_1	1232443.BAIA02000065_gene1039	4.55e-71	250.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,2487C@186801|Clostridia,268V4@186813|unclassified Clostridiales	186801|Clostridia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
WZS3_k127_5588317_7	742733.HMPREF9469_03886	2.366e-06	53.0	2DRAE@1|root,33AY6@2|Bacteria,1UICR@1239|Firmicutes,25GR5@186801|Clostridia	186801|Clostridia	N	Flagellar biosynthesis protein, FliO	-	-	-	-	-	-	-	-	-	-	-	-	FliO
WZS3_k127_5588317_5	1121334.KB911069_gene1602	1.271e-14	83.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia,3WIVA@541000|Ruminococcaceae	186801|Clostridia	N	Flagellar motor switch protein FliN	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
WZS3_k127_5588317_2	445972.ANACOL_01550	7.973e-47	178.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia,3WKC0@541000|Ruminococcaceae	186801|Clostridia	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
WZS3_k127_5588317_0	1235835.C814_03262	2.02e-86	293.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia,3WIBF@541000|Ruminococcaceae	186801|Clostridia	N	MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
WZS3_k127_5588317_4	1232443.BAIA02000065_gene1032	3.142e-16	79.0	COG1582@1|root,COG1582@2|Bacteria	2|Bacteria	N	Flagellar protein (FlbD)	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
WZS3_k127_5606385_1	272562.CA_C2021	5.238e-06	51.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,36E4B@31979|Clostridiaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
WZS3_k127_5606385_0	1123009.AUID01000028_gene344	1.372e-208	666.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,267IN@186813|unclassified Clostridiales	186801|Clostridia	HP	MoeA C-terminal region (domain IV)	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
WZS3_k127_5614819_3	585501.HMPREF6123_0053	5.632e-25	105.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,2PSBX@265975|Oribacterium	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
WZS3_k127_5614819_0	469596.HMPREF9488_01184	4.795e-182	578.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,3VNZ4@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WZS3_k127_5614819_1	351627.Csac_1605	9.64e-87	293.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,42F9Z@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
WZS3_k127_5614819_2	445971.ANASTE_02109	1.518e-55	202.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,25VUM@186806|Eubacteriaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
WZS3_k127_5654253_0	1121335.Clst_0657	1.178e-143	464.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,2494X@186801|Clostridia,3WIGS@541000|Ruminococcaceae	186801|Clostridia	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
WZS3_k127_5654253_6	1318628.MARLIPOL_02860	1.949e-53	197.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1S48Y@1236|Gammaproteobacteria,467A1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
WZS3_k127_5654253_8	1211819.CALK01000044_gene949	2.459e-43	164.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,3VR14@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	QueT
WZS3_k127_5654253_5	1232447.BAHW02000027_gene2012	3.211e-58	210.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,2680E@186813|unclassified Clostridiales	186801|Clostridia	H	ThiF family	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
WZS3_k127_5654253_1	555088.DealDRAFT_1482	6.366e-108	354.0	COG1432@1|root,COG1432@2|Bacteria,1TTAC@1239|Firmicutes,249NE@186801|Clostridia	186801|Clostridia	NU	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
WZS3_k127_5654253_2	1121874.KB892377_gene920	2.718e-90	306.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,3VPGX@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Cell wall formation	-	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
WZS3_k127_5654253_3	1122925.KB895400_gene114	1.59e-71	258.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli,26QQR@186822|Paenibacillaceae	91061|Bacilli	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
WZS3_k127_5654253_7	536233.CLO_1218	5.289e-47	171.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24NFX@186801|Clostridia,36K0Z@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
WZS3_k127_5654253_4	59374.Fisuc_0446	7.031e-66	235.0	COG1104@1|root,COG1104@2|Bacteria	2|Bacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS2	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS3_k127_5656086_1	545696.HOLDEFILI_02977	2.808e-88	296.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,3VPH4@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
WZS3_k127_5656086_0	469596.HMPREF9488_01812	2.997e-186	587.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,3VNXH@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WZS3_k127_5658698_3	999413.HMPREF1094_01540	9.024e-68	239.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,3VQBF@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
WZS3_k127_5658698_2	545696.HOLDEFILI_00351	8.604e-131	434.0	COG0739@1|root,COG3583@1|root,COG0739@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,3VNTU@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
WZS3_k127_5658698_1	1211819.CALK01000023_gene1683	4.766e-173	553.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,3VNVZ@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
WZS3_k127_5658698_5	469596.HMPREF9488_03555	8.932e-41	155.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,3VQM2@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
WZS3_k127_5658698_0	545696.HOLDEFILI_00348	1.413e-191	617.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,3VPDW@526524|Erysipelotrichia	526524|Erysipelotrichia	T	DHHA1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
WZS3_k127_5658698_6	545696.HOLDEFILI_00347	9.273e-36	148.0	COG4241@1|root,COG4241@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2232)	yybS	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	DUF2232
WZS3_k127_5658698_7	428126.CLOSPI_02451	1.47e-35	136.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,3VRD8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
WZS3_k127_5658698_4	545696.HOLDEFILI_00345	3.244e-42	159.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,3VQH3@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
WZS3_k127_5667963_1	1410668.JNKC01000002_gene2119	2.248e-62	215.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,36E64@31979|Clostridiaceae	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	kduD	-	1.1.1.127,1.1.1.69	ko:K00046,ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
WZS3_k127_5667963_0	991.IW20_21245	3.378e-189	601.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	ygcE	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
WZS3_k127_5667963_2	1304866.K413DRAFT_4457	2.145e-59	215.0	COG0778@1|root,COG0778@2|Bacteria,1V0NJ@1239|Firmicutes,24FM7@186801|Clostridia,36EJ6@31979|Clostridiaceae	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase
WZS3_k127_5667963_3	1121936.AUHI01000021_gene2751	7.131e-47	175.0	COG3457@1|root,COG3457@2|Bacteria,1TNYJ@1239|Firmicutes,4HBIA@91061|Bacilli	91061|Bacilli	E	Racemase	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
WZS3_k127_5668464_4	1286171.EAL2_808p06220	3.038e-111	366.0	COG1306@1|root,COG1306@2|Bacteria,1TQZV@1239|Firmicutes,24ADG@186801|Clostridia	186801|Clostridia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
WZS3_k127_5668464_5	1286171.EAL2_808p06230	1.81e-109	364.0	COG0726@1|root,COG0726@2|Bacteria,1TRUR@1239|Firmicutes,24D1N@186801|Clostridia,25YRX@186806|Eubacteriaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
WZS3_k127_5668464_3	1519439.JPJG01000031_gene1736	5.073e-124	404.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,2N6XI@216572|Oscillospiraceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
WZS3_k127_5668464_7	1196095.GAPWK_1748	7.097e-16	87.0	2DBVD@1|root,2ZBAJ@2|Bacteria,1N0UA@1224|Proteobacteria,1S1HZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2877)	ylbF	-	-	-	-	-	-	-	-	-	-	-	DUF2877
WZS3_k127_5668464_2	994573.T472_0207040	2.604e-150	486.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,36DYZ@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
WZS3_k127_5668464_0	994573.T472_0207045	4.911e-201	632.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,36DYZ@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltT	-	-	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23,2.A.23.1.1,2.A.23.1.2,2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
WZS3_k127_5668464_1	865861.AZSU01000003_gene2282	1.328e-170	548.0	COG0074@1|root,COG0074@2|Bacteria,1UJ4F@1239|Firmicutes,24AQG@186801|Clostridia,36HIH@31979|Clostridiaceae	186801|Clostridia	C	Protein of unknown function (DUF1116)	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,DUF1116,Ligase_CoA
WZS3_k127_5668464_6	1410619.SRDD_01340	3.749e-54	198.0	COG0074@1|root,COG0074@2|Bacteria,1MWWN@1224|Proteobacteria,1RME7@1236|Gammaproteobacteria,402R6@613|Serratia	1224|Proteobacteria	C	CoA-ligase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Ligase_CoA
WZS3_k127_5675691_1	1403313.AXBR01000023_gene2452	5.73e-10	63.0	COG2508@1|root,COG2508@2|Bacteria,1V649@1239|Firmicutes,4HHCD@91061|Bacilli,1ZH98@1386|Bacillus	91061|Bacilli	QT	PucR C-terminal helix-turn-helix domain	lrp	-	-	-	-	-	-	-	-	-	-	-	HTH_30
WZS3_k127_5675691_0	1211819.CALK01000020_gene852	3.269e-133	428.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,3VNPX@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
WZS3_k127_5710283_1	1232447.BAHW02000049_gene3072	6.571e-30	118.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
WZS3_k127_5710283_0	871963.Desdi_0914	5.984e-51	196.0	COG0739@1|root,COG3583@1|root,COG0739@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia,260WV@186807|Peptococcaceae	186801|Clostridia	M	PFAM Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
WZS3_k127_5712394_0	702450.CUW_2695	3.961e-80	273.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,3VQUZ@526524|Erysipelotrichia	526524|Erysipelotrichia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_5720729_0	457405.FSDG_00693	1.576e-126	410.0	COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria	32066|Fusobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
WZS3_k127_5720729_1	706433.HMPREF9430_00893	9.659e-54	200.0	COG4552@1|root,COG4552@2|Bacteria,1UKDA@1239|Firmicutes,3VQ25@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
WZS3_k127_572370_1	207559.Dde_1100	4.181e-18	87.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2M8JZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WZS3_k127_572370_0	1123313.ATUT01000009_gene1689	1.784e-117	390.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,3VNQ4@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
WZS3_k127_572370_2	545697.HMPREF0216_00246	2.433e-14	76.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,36ECQ@31979|Clostridiaceae	186801|Clostridia	E	Cysteine desulfurase	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
WZS3_k127_5723889_0	1211819.CALK01000004_gene2290	1.927e-88	294.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,3VP1H@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WZS3_k127_5723889_4	545696.HOLDEFILI_03075	7.203e-39	146.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,3VR5Y@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
WZS3_k127_5723889_2	1235835.C814_01098	1.104e-47	186.0	COG0739@1|root,COG0739@2|Bacteria,1V7QV@1239|Firmicutes,24M4A@186801|Clostridia,3WPC6@541000|Ruminococcaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
WZS3_k127_5723889_3	1454004.AW11_01069	6.509e-47	172.0	COG3743@1|root,COG3743@2|Bacteria,1RA3K@1224|Proteobacteria,2VVIG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
WZS3_k127_5723889_1	1286171.EAL2_c08000	1.297e-50	186.0	COG5403@1|root,COG5403@2|Bacteria,1VBV8@1239|Firmicutes,24P5S@186801|Clostridia	186801|Clostridia	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
WZS3_k127_5728426_1	428127.EUBDOL_01385	6.489e-47	171.0	COG0221@1|root,COG0221@2|Bacteria,1V8EF@1239|Firmicutes,3VR30@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5728426_0	658659.HMPREF0983_00195	2.359e-108	363.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,3VPVG@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	TRAM,tRNA_U5-meth_tr
WZS3_k127_5735988_2	545696.HOLDEFILI_03465	2.033e-57	209.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,3VQ6Q@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
WZS3_k127_5735988_1	545696.HOLDEFILI_03466	3.889e-59	210.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,3VQRH@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
WZS3_k127_5735988_0	545696.HOLDEFILI_03224	2.051e-95	317.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,3VPWU@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_5757383_5	1160721.RBI_I00372	4.115e-69	248.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
WZS3_k127_5757383_6	410358.Mlab_0394	2.648e-44	172.0	COG0248@1|root,arCOG05138@2157|Archaea,2XZYT@28890|Euryarchaeota	28890|Euryarchaeota	F	PFAM Ppx GppA phosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
WZS3_k127_5757383_0	702450.CUW_0702	3.792e-219	697.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,3VPG7@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Alpha amylase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WZS3_k127_5757383_4	580331.Thit_2103	8.427e-81	279.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,42GEV@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM PfkB domain protein	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WZS3_k127_5757383_3	1123274.KB899414_gene3709	3.531e-106	351.0	COG0395@1|root,COG0395@2|Bacteria,2J786@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
WZS3_k127_5757383_2	744872.Spica_2121	2.676e-112	371.0	COG1175@1|root,COG1175@2|Bacteria,2J5HQ@203691|Spirochaetes	203691|Spirochaetes	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
WZS3_k127_5757383_1	1123274.KB899414_gene3707	1.342e-157	507.0	COG1653@1|root,COG1653@2|Bacteria,2J66N@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Bacterial extracellular solute-binding	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
WZS3_k127_5757383_7	998088.B565_3635	1.506e-05	49.0	COG1609@1|root,COG1609@2|Bacteria,1MU1G@1224|Proteobacteria,1RMSP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	galR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_5777113_3	1294142.CINTURNW_4310	1.362e-22	101.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia,36M0N@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5777113_1	1033734.CAET01000042_gene457	8.759e-145	466.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli,1ZB5V@1386|Bacillus	91061|Bacilli	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
WZS3_k127_5777113_0	350688.Clos_0297	3.5e-151	487.0	COG3919@1|root,COG3919@2|Bacteria,1TQPN@1239|Firmicutes,248Y0@186801|Clostridia,36GDR@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CPSase_L_D2,Dala_Dala_lig_C
WZS3_k127_5777113_2	1511.CLOST_1591	6.783e-66	234.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,24ADY@186801|Clostridia	186801|Clostridia	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
WZS3_k127_5777113_4	411471.SUBVAR_05299	6.587e-06	48.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3WGQ3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
WZS3_k127_5796168_0	552396.HMPREF0863_00828	1.556e-120	390.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,3VNR2@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WZS3_k127_5796168_3	545696.HOLDEFILI_03072	3.285e-15	78.0	COG1694@1|root,COG1694@2|Bacteria,1W4QW@1239|Firmicutes,3VU8R@526524|Erysipelotrichia	526524|Erysipelotrichia	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
WZS3_k127_5796168_1	658659.HMPREF0983_01151	1.04e-93	319.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,3VPXH@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
WZS3_k127_5796168_2	980584.AFPB01000142_gene1148	7.819e-17	85.0	COG5403@1|root,COG5403@2|Bacteria,4NEX0@976|Bacteroidetes,1HYHW@117743|Flavobacteriia,4076J@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
WZS3_k127_5812921_7	1069080.KB913028_gene1384	8.699e-37	139.0	2DVFX@1|root,33VQ8@2|Bacteria,1VW7G@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
WZS3_k127_5812921_8	994573.T472_0216650	1.842e-28	121.0	COG3449@1|root,COG3449@2|Bacteria,1V4SC@1239|Firmicutes,24RPG@186801|Clostridia,36SSX@31979|Clostridiaceae	186801|Clostridia	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
WZS3_k127_5812921_1	1511.CLOST_1564	1.408e-148	473.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,25S8A@186804|Peptostreptococcaceae	186801|Clostridia	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
WZS3_k127_5812921_2	697281.Mahau_1429	3.296e-143	465.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,42FGQ@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
WZS3_k127_5812921_4	457396.CSBG_02979	9.281e-92	308.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,36DG7@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
WZS3_k127_5812921_5	938288.HG326228_gene258	4.715e-60	212.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,268RV@186813|unclassified Clostridiales	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
WZS3_k127_5812921_9	1367847.JCM7686_2781	8.581e-06	51.0	COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria,2UJAV@28211|Alphaproteobacteria,2PXY3@265|Paracoccus	28211|Alphaproteobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
WZS3_k127_5812921_3	1123511.KB905848_gene2945	5.696e-134	450.0	COG3064@1|root,COG3437@1|root,COG3064@2|Bacteria,COG3437@2|Bacteria,1TQ0S@1239|Firmicutes,4H3CB@909932|Negativicutes	909932|Negativicutes	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD,HD_5,PAS_9
WZS3_k127_5812921_0	1298920.KI911353_gene1833	1.093e-316	972.0	COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,247Y1@186801|Clostridia,21Y68@1506553|Lachnoclostridium	186801|Clostridia	C	Catalase	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
WZS3_k127_5812921_6	1298920.KI911353_gene1834	8.249e-51	183.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia,2208T@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
WZS3_k127_5814056_0	545696.HOLDEFILI_01710	9.517e-122	401.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,3VPY6@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_5814056_2	357809.Cphy_3733	1.108e-41	163.0	COG0584@1|root,COG0584@2|Bacteria,1V3Z1@1239|Firmicutes,24C71@186801|Clostridia,220H8@1506553|Lachnoclostridium	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
WZS3_k127_5814056_1	545696.HOLDEFILI_01708	3.124e-59	210.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,3VQVE@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
WZS3_k127_5814056_3	1123230.ARQJ01000015_gene1018	4.587e-05	46.0	2EG8N@1|root,33A0G@2|Bacteria,1UPXN@1239|Firmicutes,4IVCR@91061|Bacilli,4H0YC@90964|Staphylococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5852367_3	877415.JNJQ01000001_gene2078	1.933e-16	83.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,3VRA8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
WZS3_k127_5852367_2	545696.HOLDEFILI_03736	2.276e-27	112.0	COG1837@1|root,COG1837@2|Bacteria,1VE0F@1239|Firmicutes,3VRIX@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
WZS3_k127_5852367_1	1449335.JQLG01000004_gene2078	1.817e-40	151.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,27GK9@186828|Carnobacteriaceae	91061|Bacilli	J	Ribosomal protein S16	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
WZS3_k127_5852367_0	650150.ERH_0510	9.408e-111	366.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,3VNYU@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
WZS3_k127_5886050_0	1121930.AQXG01000001_gene1240	3.704e-34	134.0	COG3865@1|root,COG3865@2|Bacteria,4NE70@976|Bacteroidetes,1ISXP@117747|Sphingobacteriia	976|Bacteroidetes	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
WZS3_k127_5892432_2	1121874.KB892378_gene413	4.883e-10	70.0	COG1286@1|root,COG1286@2|Bacteria,1VHHC@1239|Firmicutes,3VRUH@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Colicin V production protein	cvpA	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
WZS3_k127_5892432_0	1211819.CALK01000029_gene1972	1.274e-231	727.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,3VNQF@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
WZS3_k127_5892432_1	401526.TcarDRAFT_0383	4.825e-28	115.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4H53Y@909932|Negativicutes	909932|Negativicutes	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
WZS3_k127_5908448_7	350688.Clos_0651	2.184e-34	133.0	COG0524@1|root,COG1846@1|root,COG0524@2|Bacteria,COG1846@2|Bacteria,1TQR4@1239|Firmicutes,24AUP@186801|Clostridia,36F1Z@31979|Clostridiaceae	186801|Clostridia	G	hmm pf00294	rbsK	-	2.7.1.15,2.7.1.83	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	-	R01051,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HTH_24,PfkB
WZS3_k127_5908448_1	445974.CLORAM_02171	4.799e-153	499.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,3VP8Z@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
WZS3_k127_5908448_3	1123008.KB905701_gene2171	4.565e-122	404.0	COG2133@1|root,COG2133@2|Bacteria,4NEZC@976|Bacteroidetes,2FSM8@200643|Bacteroidia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,GSDH
WZS3_k127_5908448_6	1121874.KB892379_gene355	5.99e-37	150.0	COG0561@1|root,COG0561@2|Bacteria,1TQFX@1239|Firmicutes,3VUHQ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_5908448_4	658659.HMPREF0983_02366	1.251e-82	281.0	COG1349@1|root,COG1349@2|Bacteria,1UYQX@1239|Firmicutes,3VNQT@526524|Erysipelotrichia	526524|Erysipelotrichia	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
WZS3_k127_5908448_8	1232449.BAHV02000019_gene1365	4.265e-24	112.0	2CBC6@1|root,32RT3@2|Bacteria,1VAHQ@1239|Firmicutes,251AP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_5908448_0	1232449.BAHV02000035_gene3232	7.11e-199	623.0	COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,249MG@186801|Clostridia	186801|Clostridia	S	Beta-lactamase superfamily domain	ulaG	-	-	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactamase_B_2,Lactamase_B_3
WZS3_k127_5908448_5	180332.JTGN01000002_gene5546	1.241e-51	186.0	COG1762@1|root,COG1762@2|Bacteria,1V892@1239|Firmicutes,24QVP@186801|Clostridia	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	PTS_EIIA_2
WZS3_k127_5908448_2	1232449.BAHV02000018_gene1721	6.325e-142	455.0	COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,247MD@186801|Clostridia	186801|Clostridia	S	sugar-specific permease SgaT UlaA	ulaA	-	-	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.7.1	-	-	EIIC-GAT
WZS3_k127_5928063_0	1408416.JNJT01000002_gene171	2.102e-130	419.0	COG0332@1|root,COG0332@2|Bacteria,3WUE2@544448|Tenericutes	544448|Tenericutes	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
WZS3_k127_5928063_1	1410668.JNKC01000004_gene57	7.537e-127	412.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,36DZ6@31979|Clostridiaceae	186801|Clostridia	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
WZS3_k127_5931712_0	908340.HMPREF9406_4200	6.731e-61	224.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,36F0A@31979|Clostridiaceae	186801|Clostridia	GKT	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
WZS3_k127_5931712_1	908340.HMPREF9406_4199	2.222e-25	109.0	COG1762@1|root,COG1762@2|Bacteria,1VDJE@1239|Firmicutes,25BXU@186801|Clostridia	186801|Clostridia	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
WZS3_k127_6052789_2	1235835.C814_00577	1.106e-15	86.0	COG3458@1|root,COG3458@2|Bacteria,1TS02@1239|Firmicutes,24A6N@186801|Clostridia,3WJK8@541000|Ruminococcaceae	186801|Clostridia	Q	PFAM Acetyl xylan esterase	axe1	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
WZS3_k127_6052789_3	1111121.HMPREF1247_1024	0.0002224	51.0	COG3458@1|root,COG3458@2|Bacteria	2|Bacteria	Q	cephalosporin-C deacetylase activity	cah	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
WZS3_k127_6052789_0	411902.CLOBOL_00412	5.425e-147	484.0	COG0747@1|root,COG0747@2|Bacteria,1VUKJ@1239|Firmicutes,24EI4@186801|Clostridia,21ZME@1506553|Lachnoclostridium	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
WZS3_k127_6052789_1	742733.HMPREF9469_04201	1.18e-50	184.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,21ZIG@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
WZS3_k127_6056272_0	702450.CUW_0105	6.634e-88	298.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,3VNUF@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WZS3_k127_6056272_1	545696.HOLDEFILI_00292	9.124e-15	75.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,3VNUF@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Malt_amylase_C
WZS3_k127_6063444_0	1232449.BAHV02000010_gene3111	6.557e-120	397.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,267P4@186813|unclassified Clostridiales	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
WZS3_k127_6070826_1	457421.CBFG_02674	3.069e-25	110.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,2596N@186801|Clostridia,269US@186813|unclassified Clostridiales	186801|Clostridia	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
WZS3_k127_6070826_0	658086.HMPREF0994_00528	1.057e-57	203.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia,27N1Y@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
WZS3_k127_6070826_2	1105031.HMPREF1141_2805	1.189e-14	77.0	COG1677@1|root,COG1677@2|Bacteria,1U4CI@1239|Firmicutes,259BS@186801|Clostridia,36NAY@31979|Clostridiaceae	186801|Clostridia	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	-	-	-	-	-	-	-	-	-	FliE
WZS3_k127_6078385_5	679192.HMPREF9013_0611	2.527e-14	73.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,3VNYX@526524|Erysipelotrichia	526524|Erysipelotrichia	GK	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
WZS3_k127_6078385_0	1211819.CALK01000009_gene2782	6.036e-229	717.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,3VP3W@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Psort location Cytoplasmic, score 8.87	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
WZS3_k127_6078385_1	428127.EUBDOL_00241	5.863e-144	462.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,3VPCB@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
WZS3_k127_6078385_2	1232449.BAHV02000011_gene2150	1.062e-58	214.0	COG1484@1|root,COG1484@2|Bacteria,1V8DQ@1239|Firmicutes,24M56@186801|Clostridia	186801|Clostridia	L	Bacterial dnaA  protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA,IstB_IS21
WZS3_k127_6078385_3	1232449.BAHV02000011_gene2149	3.924e-38	157.0	COG3611@1|root,COG3611@2|Bacteria,1W7BH@1239|Firmicutes,24XW4@186801|Clostridia	186801|Clostridia	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
WZS3_k127_6078385_4	428127.EUBDOL_00238	2.293e-30	127.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,3VRGI@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
WZS3_k127_6081226_0	565664.EFXG_01987	1.992e-33	129.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4H9KU@91061|Bacilli,4AZEB@81852|Enterococcaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 1 family	bglC	-	3.2.1.21,3.2.1.86	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	-	R00026,R00839,R02558,R02887,R02985,R03527,R04949,R04998,R05133,R05134,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
WZS3_k127_6081226_1	665950.HMPREF1025_02575	1.536e-21	96.0	COG2246@1|root,COG2246@2|Bacteria,1VDQH@1239|Firmicutes,24N8P@186801|Clostridia,27TRR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
WZS3_k127_6100539_10	714961.BFZC1_19983	0.0005539	47.0	COG4967@1|root,COG4967@2|Bacteria,1VKH2@1239|Firmicutes,4HR58@91061|Bacilli,3IYUI@400634|Lysinibacillus	91061|Bacilli	NU	type IV pilus modification protein PilV	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WZS3_k127_6100539_3	428126.CLOSPI_01838	1.851e-70	247.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,3VQBE@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
WZS3_k127_6100539_1	994573.T472_0200460	7.195e-115	382.0	COG0025@1|root,COG0025@2|Bacteria,1UHUI@1239|Firmicutes,25E2Y@186801|Clostridia,36UH5@31979|Clostridiaceae	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
WZS3_k127_6100539_4	1123009.AUID01000018_gene323	3.086e-47	175.0	2CK8D@1|root,32SBU@2|Bacteria,1VAQG@1239|Firmicutes,24HSZ@186801|Clostridia,26BR1@186813|unclassified Clostridiales	186801|Clostridia	S	Tryptophan transporter TrpP	trpP	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS14305	TrpP
WZS3_k127_6100539_2	545696.HOLDEFILI_02683	3.112e-103	349.0	COG0477@1|root,COG2814@2|Bacteria,1UZPE@1239|Firmicutes,3VQPQ@526524|Erysipelotrichia	526524|Erysipelotrichia	EGP	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
WZS3_k127_6100539_5	382464.ABSI01000011_gene2544	7.487e-46	171.0	COG0663@1|root,COG0663@2|Bacteria,46V7F@74201|Verrucomicrobia,2IU9X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
WZS3_k127_6100539_9	509191.AEDB02000052_gene1365	9.76e-07	61.0	2E3R1@1|root,32YNU@2|Bacteria,1VEND@1239|Firmicutes,24RRZ@186801|Clostridia,3WKJ8@541000|Ruminococcaceae	186801|Clostridia	S	Anti-sigma factor N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RsgI_N
WZS3_k127_6100539_7	243164.DET0169	9.289e-34	137.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
WZS3_k127_6100539_8	1042876.PPS_3865	4.165e-21	97.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,1SCJZ@1236|Gammaproteobacteria,1YZJH@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
WZS3_k127_6100539_6	1408306.JHXX01000003_gene1166	1.719e-36	153.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia,4BWN2@830|Butyrivibrio	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
WZS3_k127_6100539_0	650150.ERH_1401	1.078e-166	532.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,3VNXB@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Psort location CytoplasmicMembrane, score	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
WZS3_k127_6101336_1	926692.AZYG01000085_gene777	6.867e-46	174.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,249QZ@186801|Clostridia	186801|Clostridia	S	Oxidoreductase NAD-binding domain protein	-	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
WZS3_k127_6101336_2	314607.KB13_1125	6.902e-07	59.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,1KQ0N@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	HL	Thiamine monophosphate synthase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
WZS3_k127_6101336_0	1158606.I579_00711	5.812e-56	200.0	COG0560@1|root,COG0560@2|Bacteria,1TRRS@1239|Firmicutes,4HU51@91061|Bacilli	91061|Bacilli	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HAD
WZS3_k127_613582_1	877411.JMMA01000002_gene2955	1.57e-34	135.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia,3WSIE@541000|Ruminococcaceae	186801|Clostridia	NU	ATPase FliI YscN family	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
WZS3_k127_613582_3	1514668.JOOA01000002_gene3204	8.579e-23	102.0	COG1843@1|root,COG1843@2|Bacteria,1UQ80@1239|Firmicutes,257XT@186801|Clostridia,3WK8J@541000|Ruminococcaceae	186801|Clostridia	N	Required for flagellar hook formation. May act as a scaffolding protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgD
WZS3_k127_613582_2	658086.HMPREF0994_00559	1.03e-32	131.0	2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,24R2S@186801|Clostridia,27NZM@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Putative flagellar	flg	-	-	-	-	-	-	-	-	-	-	-	Flagellar_put
WZS3_k127_613582_0	658086.HMPREF0994_00558	1.244e-130	434.0	COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,247ZT@186801|Clostridia,27I5I@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Flagellar basal body rod FlgEFG protein C-terminal	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
WZS3_k127_613582_4	877411.JMMA01000002_gene2961	3.635e-16	79.0	COG1582@1|root,COG1582@2|Bacteria,1URP0@1239|Firmicutes,259J5@186801|Clostridia,3WMPP@541000|Ruminococcaceae	186801|Clostridia	N	Flagellar protein (FlbD)	-	-	-	-	-	-	-	-	-	-	-	-	FlbD
WZS3_k127_6138871_4	1294142.CINTURNW_1852	4.23e-54	199.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,24B1N@186801|Clostridia,36F7Q@31979|Clostridiaceae	186801|Clostridia	S	hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_6138871_3	1232446.BAIE02000055_gene3053	1.677e-59	216.0	COG1737@1|root,COG1737@2|Bacteria,1V00A@1239|Firmicutes,249MY@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
WZS3_k127_6138871_2	1541960.KQ78_01748	9.532e-64	235.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_17
WZS3_k127_6138871_5	1507.HMPREF0262_03018	2.035e-37	143.0	2CDKX@1|root,32RXZ@2|Bacteria,1VC7P@1239|Firmicutes,24MMR@186801|Clostridia,36KQ1@31979|Clostridiaceae	186801|Clostridia	S	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	DUF4387
WZS3_k127_6138871_0	696281.Desru_1990	2.163e-194	615.0	COG1574@1|root,COG1574@2|Bacteria,1UY5C@1239|Firmicutes,24A2S@186801|Clostridia,263W6@186807|Peptococcaceae	186801|Clostridia	S	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
WZS3_k127_6138871_1	401526.TcarDRAFT_1177	5.86e-136	440.0	COG3799@1|root,COG3799@2|Bacteria,1TQ7T@1239|Firmicutes,4H3WN@909932|Negativicutes	909932|Negativicutes	E	PFAM Methylaspartate ammonia-lyase	-	-	4.3.1.2	ko:K04835	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R03696	RC00979	ko00000,ko00001,ko00002,ko01000	-	-	-	MAAL_C,MAAL_N
WZS3_k127_6150871_2	865861.AZSU01000002_gene3110	1.183e-29	125.0	COG0500@1|root,COG2226@2|Bacteria,1V6G6@1239|Firmicutes,24H8Z@186801|Clostridia	186801|Clostridia	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
WZS3_k127_6150871_1	1282360.ABAC460_13425	4.532e-31	132.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,2TS11@28211|Alphaproteobacteria,2KG6A@204458|Caulobacterales	204458|Caulobacterales	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
WZS3_k127_6150871_0	768706.Desor_4312	4.025e-56	201.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,249X1@186801|Clostridia,2649J@186807|Peptococcaceae	186801|Clostridia	C	Alcohol dehydrogenase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
WZS3_k127_6154566_4	1235803.C825_01932	1.827e-22	99.0	COG0127@1|root,COG0127@2|Bacteria,4NM42@976|Bacteroidetes,2FP46@200643|Bacteroidia,22XN1@171551|Porphyromonadaceae	976|Bacteroidetes	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
WZS3_k127_6154566_2	545696.HOLDEFILI_03504	5.095e-34	147.0	COG4478@1|root,COG4478@2|Bacteria,1VA1P@1239|Firmicutes,3VR59@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
WZS3_k127_6154566_3	1540257.JQMW01000014_gene182	2.892e-23	114.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,36JKA@31979|Clostridiaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
WZS3_k127_6154566_0	1211819.CALK01000006_gene2546	5.27e-72	247.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,3VQCB@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
WZS3_k127_6154566_1	1211819.CALK01000006_gene2551	3.383e-65	227.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,3VQQV@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
WZS3_k127_6154566_5	1385514.N782_13980	6.881e-14	78.0	COG4903@1|root,COG4903@2|Bacteria,1V4S5@1239|Firmicutes,4HHF4@91061|Bacilli,2YAEF@289201|Pontibacillus	91061|Bacilli	K	Competence protein	comK	-	-	ko:K02250	ko02024,map02024	-	-	-	ko00000,ko00001,ko02044,ko03000	-	-	-	ComK
WZS3_k127_6156666_3	1211819.CALK01000004_gene2308	1.005e-59	214.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,3VQEP@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_6156666_2	545696.HOLDEFILI_03111	6.108e-127	424.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,3VPNQ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
WZS3_k127_6156666_5	1211819.CALK01000004_gene2306	1.323e-27	119.0	2ECE7@1|root,336CG@2|Bacteria,1VGIC@1239|Firmicutes,3VR9Z@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6156666_0	706433.HMPREF9430_00619	1.194e-168	540.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,3VP3Z@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
WZS3_k127_6156666_1	1211819.CALK01000004_gene2299	2.115e-146	469.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,3VP13@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Psort location Cytoplasmic, score	ccpA	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_6156666_7	428127.EUBDOL_01073	2.366e-05	51.0	2EA5J@1|root,334AE@2|Bacteria,1VJC1@1239|Firmicutes,3VRYP@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6156666_4	1211819.CALK01000004_gene2294	3.272e-47	172.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,3VP48@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
WZS3_k127_6158427_1	1121947.AUHK01000018_gene511	2.787e-80	269.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,22GX2@1570339|Peptoniphilaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
WZS3_k127_6158427_3	545696.HOLDEFILI_01190	9.514e-23	101.0	COG3343@1|root,COG3343@2|Bacteria,1VHBT@1239|Firmicutes,3VRJJ@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling	rpoE	-	-	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	-	-	-	HARE-HTH
WZS3_k127_6158427_0	545696.HOLDEFILI_01191	6.228e-234	735.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,3VP4K@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
WZS3_k127_6158427_2	1408422.JHYF01000009_gene2081	3.559e-69	243.0	2C3WU@1|root,303AS@2|Bacteria,1V61S@1239|Firmicutes,24HVN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K16905	ko02010,map02010	M00224	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	-
WZS3_k127_6163648_5	1131812.JQMS01000001_gene2831	1.566e-54	194.0	COG3403@1|root,COG3403@2|Bacteria,4PJVB@976|Bacteroidetes,1IE2W@117743|Flavobacteriia,2NZR6@237|Flavobacterium	976|Bacteroidetes	S	YqcI/YcgG family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6163648_10	1131812.JQMS01000001_gene2831	6.705e-09	57.0	COG3403@1|root,COG3403@2|Bacteria,4PJVB@976|Bacteroidetes,1IE2W@117743|Flavobacteriia,2NZR6@237|Flavobacterium	976|Bacteroidetes	S	YqcI/YcgG family	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6163648_3	1121324.CLIT_11c01480	4.364e-116	397.0	COG5492@1|root,COG5492@2|Bacteria,1VUQN@1239|Firmicutes	1239|Firmicutes	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,F5_F8_type_C,Flg_new,SLH
WZS3_k127_6163648_9	632245.CLP_4382	5.228e-09	63.0	2AIX9@1|root,319EX@2|Bacteria,1V7X2@1239|Firmicutes,24J87@186801|Clostridia,36JYE@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6163648_8	545696.HOLDEFILI_03782	3.169e-12	68.0	COG2608@1|root,COG2608@2|Bacteria,1W3F7@1239|Firmicutes,3VUCD@526524|Erysipelotrichia	526524|Erysipelotrichia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
WZS3_k127_6163648_4	1211819.CALK01000017_gene503	7.827e-93	310.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,3VPHM@526524|Erysipelotrichia	526524|Erysipelotrichia	F	purine-nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
WZS3_k127_6163648_0	411465.PEPMIC_01489	1.765e-139	456.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,22G3S@1570339|Peptoniphilaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WZS3_k127_6163648_2	411465.PEPMIC_01489	1.365e-120	402.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,22G3S@1570339|Peptoniphilaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
WZS3_k127_6163648_1	1211819.CALK01000017_gene506	5.624e-127	417.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,3VPCP@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	-	-	-	-	-	-	-	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
WZS3_k127_6163648_6	1033810.HLPCO_003133	9.644e-38	149.0	COG1051@1|root,COG1051@2|Bacteria,2NPZ5@2323|unclassified Bacteria	2|Bacteria	F	NUDIX domain	yjhB	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX,Nudix_N
WZS3_k127_616444_2	1232449.BAHV02000010_gene2893	2.831e-60	210.0	COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,25CCC@186801|Clostridia,268MS@186813|unclassified Clostridiales	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
WZS3_k127_616444_1	428127.EUBDOL_00517	2.166e-145	467.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,3VPR9@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
WZS3_k127_616444_0	1211819.CALK01000028_gene1946	5.27e-317	979.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,3VP7V@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind,SecA_SW
WZS3_k127_6184407_2	1321778.HMPREF1982_04392	7.177e-53	191.0	COG2021@1|root,COG2021@2|Bacteria,1UN4B@1239|Firmicutes	1239|Firmicutes	E	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
WZS3_k127_6184407_0	1321778.HMPREF1982_04391	1.483e-71	246.0	COG1309@1|root,COG1309@2|Bacteria,1V2I9@1239|Firmicutes,24K9G@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_6184407_1	1232449.BAHV02000018_gene1635	3.458e-55	198.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,2691F@186813|unclassified Clostridiales	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
WZS3_k127_6184407_3	1499684.CCNP01000018_gene660	1.078e-49	180.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24BV5@186801|Clostridia,36GUE@31979|Clostridiaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_6185756_1	545696.HOLDEFILI_02183	3.264e-117	392.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,3VP75@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Extracellular, score	ponA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	FIVAR,Transgly,Transpeptidase
WZS3_k127_6185756_3	1304875.JAFZ01000001_gene803	7.383e-08	58.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
WZS3_k127_6185756_0	1033734.CAET01000024_gene1176	3.097e-118	392.0	COG0477@1|root,COG0477@2|Bacteria,1UHRM@1239|Firmicutes,4ISTP@91061|Bacilli,1ZSG1@1386|Bacillus	91061|Bacilli	EGP	Transmembrane secretion effector	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1
WZS3_k127_6185756_2	1203611.KB894547_gene2732	2.219e-55	201.0	COG0266@1|root,COG0266@2|Bacteria,4NIT4@976|Bacteroidetes,2FPIR@200643|Bacteroidia	976|Bacteroidetes	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
WZS3_k127_6206271_1	994573.T472_0200885	2.42e-26	109.0	29VYD@1|root,30HGI@2|Bacteria,1V82C@1239|Firmicutes,24P63@186801|Clostridia,36T8X@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
WZS3_k127_6206271_0	994573.T472_0201645	7.924e-182	580.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,36FFS@31979|Clostridiaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24
WZS3_k127_6236737_4	428127.EUBDOL_01988	1.449e-71	247.0	COG1142@1|root,COG4624@1|root,COG1142@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,3VP8Z@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4
WZS3_k127_6236737_1	1499689.CCNN01000004_gene212	2.069e-100	334.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,36DI6@31979|Clostridiaceae	186801|Clostridia	K	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_6236737_5	1087481.AGFX01000009_gene4701	2.534e-71	251.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,4HDIH@91061|Bacilli,26U5X@186822|Paenibacillaceae	91061|Bacilli	S	hydrolases of the HAD superfamily	hmpP2	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
WZS3_k127_6236737_7	658088.HMPREF0987_01279	5.434e-49	186.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia	186801|Clostridia	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
WZS3_k127_6236737_8	1232449.BAHV02000010_gene2889	3.092e-44	170.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,24JCU@186801|Clostridia	186801|Clostridia	G	peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
WZS3_k127_6236737_10	1511.CLOST_0750	1.799e-23	103.0	COG0526@1|root,COG0526@2|Bacteria,1VFUD@1239|Firmicutes	1239|Firmicutes	CO	Thioredoxin	ydfQ	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
WZS3_k127_6236737_0	650150.ERH_1630	2.588e-134	440.0	COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,3VNZR@526524|Erysipelotrichia	526524|Erysipelotrichia	E	ABC transporter	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran,CBS
WZS3_k127_6236737_3	1121874.KB892380_gene1640	7.402e-78	265.0	COG1174@1|root,COG1174@2|Bacteria,1UHWH@1239|Firmicutes	1239|Firmicutes	P	ABC-type proline glycine betaine transport	opuCB	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
WZS3_k127_6236737_6	1121874.KB892380_gene1639	1.336e-58	209.0	COG1174@1|root,COG1174@2|Bacteria,1UHWH@1239|Firmicutes,3VUWC@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
WZS3_k127_6236737_2	1121874.KB892380_gene1638	1.102e-80	278.0	COG1732@1|root,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,3VPT7@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
WZS3_k127_6236737_9	1121929.KB898666_gene2487	1.712e-36	140.0	COG2910@1|root,COG2910@2|Bacteria,1U326@1239|Firmicutes,4ICUW@91061|Bacilli,4720T@74385|Gracilibacillus	91061|Bacilli	S	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
WZS3_k127_6240843_14	650150.ERH_0968	1.535e-34	145.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,3VP72@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
WZS3_k127_6240843_2	1211819.CALK01000004_gene2255	6.128e-138	459.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,3VP57@526524|Erysipelotrichia	526524|Erysipelotrichia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
WZS3_k127_6240843_0	545696.HOLDEFILI_03053	3.719e-234	730.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,3VP2C@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyS	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
WZS3_k127_6240843_11	545696.HOLDEFILI_03052	1.989e-43	168.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,3VQXQ@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	-	-	-	-	-	-	-	-	-	RecO_C,RecO_N
WZS3_k127_6240843_6	545696.HOLDEFILI_03051	1.483e-93	316.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,3VP7U@526524|Erysipelotrichia	526524|Erysipelotrichia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
WZS3_k127_6240843_9	1123263.AUKY01000001_gene177	3.545e-57	201.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,3VQU9@526524|Erysipelotrichia	526524|Erysipelotrichia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
WZS3_k127_6240843_15	552396.HMPREF0863_00960	8.522e-15	78.0	COG0818@1|root,COG0818@2|Bacteria,1TUC3@1239|Firmicutes,3VS3A@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Prokaryotic diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
WZS3_k127_6240843_12	552396.HMPREF0863_00961	6.084e-43	161.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,3VQV3@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
WZS3_k127_6240843_1	1211819.CALK01000004_gene2248	1.669e-185	596.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,3VNX9@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
WZS3_k127_6240843_10	545696.HOLDEFILI_03044	7.807e-57	205.0	COG0704@1|root,COG0704@2|Bacteria,1V66X@1239|Firmicutes,3VQQJ@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
WZS3_k127_6240843_3	350688.Clos_1119	6.586e-119	386.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,36DJ4@31979|Clostridiaceae	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
WZS3_k127_6240843_7	1286171.EAL2_c16000	4.827e-90	304.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,25W6J@186806|Eubacteriaceae	186801|Clostridia	P	permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
WZS3_k127_6240843_4	350688.Clos_1117	2.016e-113	374.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,36DTN@31979|Clostridiaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
WZS3_k127_6240843_5	1286171.EAL2_c16030	7.632e-102	340.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,25W11@186806|Eubacteriaceae	186801|Clostridia	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
WZS3_k127_6240843_8	545696.HOLDEFILI_03037	1.592e-75	268.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,3VPBG@526524|Erysipelotrichia	526524|Erysipelotrichia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
WZS3_k127_6240843_13	428127.EUBDOL_01029	2.832e-37	143.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,3VQ41@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Response regulator receiver domain protein	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
WZS3_k127_6248364_7	838561.P344_02420	1.974e-08	58.0	COG2868@1|root,COG2868@2|Bacteria	2|Bacteria	J	Cysteine protease Prp	ysxB	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
WZS3_k127_6248364_5	1232449.BAHV02000012_gene2214	5.5e-47	169.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,269C0@186813|unclassified Clostridiales	186801|Clostridia	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
WZS3_k127_6248364_0	545696.HOLDEFILI_03374	5.855e-180	572.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,3VNXZ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	cgtA	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
WZS3_k127_6248364_3	545696.HOLDEFILI_03377	4.165e-58	208.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,3VQJ5@526524|Erysipelotrichia	526524|Erysipelotrichia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
WZS3_k127_6248364_1	1121874.KB892377_gene1310	2.048e-158	505.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,3VPIM@526524|Erysipelotrichia	526524|Erysipelotrichia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
WZS3_k127_6248364_6	521003.COLINT_02626	2.367e-17	85.0	COG0607@1|root,COG0607@2|Bacteria,2HV5N@201174|Actinobacteria,4CWCQ@84998|Coriobacteriia	84998|Coriobacteriia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WZS3_k127_6248364_4	1384049.CD29_08855	1.989e-51	189.0	COG0546@1|root,COG0546@2|Bacteria,1V75Y@1239|Firmicutes,4HPZ9@91061|Bacilli	91061|Bacilli	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
WZS3_k127_6248364_2	545696.HOLDEFILI_03403	3.964e-104	349.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,3VP6U@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
WZS3_k127_6267396_4	1123312.KB904581_gene1143	2.077e-07	52.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli	91061|Bacilli	M	acetyltransferase	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
WZS3_k127_6267396_1	552396.HMPREF0863_01391	3.648e-94	314.0	COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,3VPPY@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
WZS3_k127_6267396_0	658086.HMPREF0994_01861	1.116e-158	511.0	COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,247MD@186801|Clostridia,27NQJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	PTS system sugar-specific permease component	-	-	-	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.7.1	-	-	EIIC-GAT
WZS3_k127_6267396_2	1226325.HMPREF1548_06670	2.834e-29	119.0	COG3414@1|root,COG3414@2|Bacteria,1VGDV@1239|Firmicutes,24UX3@186801|Clostridia,36PRU@31979|Clostridiaceae	186801|Clostridia	G	Pts system	-	-	2.7.1.194	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	PTS_IIB
WZS3_k127_6267396_3	1158609.I586_01231	1.391e-20	94.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4H9N4@91061|Bacilli,4AZKI@81852|Enterococcaceae	91061|Bacilli	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
WZS3_k127_6276682_2	357809.Cphy_3379	9.545e-90	305.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_6276682_0	318464.IO99_08010	8.408e-167	542.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,36GFZ@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_6276682_3	1461580.CCAS010000061_gene3879	1.768e-13	75.0	COG1846@1|root,COG1846@2|Bacteria,1VEFZ@1239|Firmicutes,4HP9T@91061|Bacilli,1ZIEU@1386|Bacillus	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	slyA3	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
WZS3_k127_6276682_1	1121874.KB892380_gene1670	1.106e-123	399.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,3VP98@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
WZS3_k127_6278736_2	1211819.CALK01000004_gene2284	3.102e-22	104.0	COG1309@1|root,COG1309@2|Bacteria,1VGTE@1239|Firmicutes,3VUE9@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_6278736_1	1511.CLOST_0668	2.964e-38	147.0	COG4852@1|root,COG4852@2|Bacteria,1VBU5@1239|Firmicutes,24Q4S@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
WZS3_k127_6278736_0	656519.Halsa_0817	1.649e-75	267.0	COG1307@1|root,COG1461@1|root,COG1307@2|Bacteria,COG1461@2|Bacteria,1TR6J@1239|Firmicutes,24A8H@186801|Clostridia,3WC9D@53433|Halanaerobiales	186801|Clostridia	S	Dak2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak2,DegV
WZS3_k127_628791_1	1211819.CALK01000042_gene3113	6.772e-78	267.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,3VPN6@526524|Erysipelotrichia	526524|Erysipelotrichia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
WZS3_k127_628791_0	545696.HOLDEFILI_01964	6.759e-172	556.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,3VP0E@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
WZS3_k127_6288635_9	83406.HDN1F_21850	2.356e-25	121.0	2DUIR@1|root,33QVE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
WZS3_k127_6288635_0	1211844.CBLM010000044_gene406	5.599e-214	674.0	COG3119@1|root,COG3119@2|Bacteria,1TPWD@1239|Firmicutes,3VPJ4@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
WZS3_k127_6288635_3	1232449.BAHV02000020_gene1298	7.582e-139	453.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,26AG8@186813|unclassified Clostridiales	186801|Clostridia	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
WZS3_k127_6288635_8	1280689.AUJC01000005_gene723	4.693e-56	204.0	COG1737@1|root,COG1737@2|Bacteria,1UYXE@1239|Firmicutes,25CEE@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6
WZS3_k127_6288635_4	742742.HMPREF9452_00542	4.311e-134	436.0	COG0641@1|root,COG0641@2|Bacteria,2HVSK@201174|Actinobacteria,4CXDG@84998|Coriobacteriia	84998|Coriobacteriia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
WZS3_k127_6288635_2	758.BBIX01000006_gene746	1.333e-172	552.0	COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,1RNCQ@1236|Gammaproteobacteria,1Y6QJ@135625|Pasteurellales	135625|Pasteurellales	EG	H gluconate symporter and permeases COG2610	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6288635_5	865861.AZSU01000002_gene2341	1.44e-114	374.0	COG1028@1|root,COG1028@2|Bacteria,1TP3G@1239|Firmicutes,24CDN@186801|Clostridia,36HDH@31979|Clostridiaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
WZS3_k127_6288635_6	1347392.CCEZ01000007_gene2114	6.913e-101	332.0	COG2057@1|root,COG2057@2|Bacteria,1TNY5@1239|Firmicutes,247ZM@186801|Clostridia,36GAR@31979|Clostridiaceae	186801|Clostridia	I	3-oxoacid CoA-transferase, B subunit	ctfB	-	2.8.3.5,2.8.3.8,2.8.3.9	ko:K01029,ko:K01035	ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS3_k127_6288635_7	1410668.JNKC01000003_gene363	2.255e-88	296.0	COG1788@1|root,COG1788@2|Bacteria,1V21Q@1239|Firmicutes,25E61@186801|Clostridia,36UK0@31979|Clostridiaceae	186801|Clostridia	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	-	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
WZS3_k127_6288635_1	1347392.CCEZ01000007_gene2116	2.039e-179	569.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,36DVG@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
WZS3_k127_6293326_2	158189.SpiBuddy_0479	8.074e-43	160.0	COG0560@1|root,COG0560@2|Bacteria,2J5Y5@203691|Spirochaetes	203691|Spirochaetes	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
WZS3_k127_6293326_3	1347087.CBYO010000022_gene3599	7.071e-35	144.0	COG0517@1|root,COG0517@2|Bacteria,1VBH9@1239|Firmicutes,4HIBM@91061|Bacilli	91061|Bacilli	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
WZS3_k127_6293326_0	742735.HMPREF9467_02488	6.822e-195	619.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,2480Q@186801|Clostridia,21XKY@1506553|Lachnoclostridium	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
WZS3_k127_6293326_1	1408226.T233_00393	8.392e-85	289.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,4HA7P@91061|Bacilli,4B1IY@81852|Enterococcaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WZS3_k127_6329434_0	1232449.BAHV02000012_gene2245	6.788e-123	399.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,267N5@186813|unclassified Clostridiales	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon
WZS3_k127_6329434_1	658659.HMPREF0983_01084	5.71e-122	400.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,3VP2H@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Psort location Cytoplasmic, score 10.00	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
WZS3_k127_6333314_3	883114.HMPREF9709_00519	2.827e-33	131.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,22GNG@1570339|Peptoniphilaceae	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
WZS3_k127_6333314_2	1034347.CAHJ01000051_gene86	3.676e-53	193.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli,1ZFSE@1386|Bacillus	91061|Bacilli	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
WZS3_k127_6333314_0	471223.GWCH70_0263	2.008e-193	616.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli,1WEF4@129337|Geobacillus	91061|Bacilli	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
WZS3_k127_6333314_1	1160707.AJIK01000018_gene2111	3.661e-117	386.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli,26CUJ@186818|Planococcaceae	91061|Bacilli	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
WZS3_k127_6339158_2	552396.HMPREF0863_00567	5.256e-109	363.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,3VNVB@526524|Erysipelotrichia	526524|Erysipelotrichia	O	typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
WZS3_k127_6339158_4	1211819.CALK01000023_gene1679	2.213e-39	151.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,3VQCY@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
WZS3_k127_6339158_5	1211819.CALK01000023_gene1678	6.225e-39	146.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,3VR4T@526524|Erysipelotrichia	526524|Erysipelotrichia	G	phosphocarrier protein HPr	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
WZS3_k127_6339158_1	1232449.BAHV02000008_gene568	3.348e-221	699.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,267KU@186813|unclassified Clostridiales	186801|Clostridia	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
WZS3_k127_6339158_0	706433.HMPREF9430_01052	5.872e-244	767.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,3VPHN@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48
WZS3_k127_6339158_3	1211819.CALK01000022_gene1667	2.734e-73	248.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,3VNXW@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase
WZS3_k127_6349814_2	1211819.CALK01000006_gene2573	1.401e-54	193.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,3VNYV@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location Cytoplasmic, score	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
WZS3_k127_6349814_3	1211819.CALK01000004_gene2266	2.149e-25	107.0	COG0268@1|root,COG0268@2|Bacteria,1TU7U@1239|Firmicutes,3VRW3@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S20p
WZS3_k127_6349814_1	1276227.SCHRY_v1c06910	1.172e-92	315.0	COG0223@1|root,COG0223@2|Bacteria,3WSZ7@544448|Tenericutes	544448|Tenericutes	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
WZS3_k127_6349814_4	926561.KB900618_gene200	8.694e-20	95.0	COG4720@1|root,COG4720@2|Bacteria,1VF2R@1239|Firmicutes,24QR3@186801|Clostridia,3WC9R@53433|Halanaerobiales	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
WZS3_k127_6349814_0	1232449.BAHV02000011_gene2125	2.1e-124	401.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,2683H@186813|unclassified Clostridiales	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
WZS3_k127_6361500_0	397290.C810_00836	5.272e-97	326.0	COG2856@1|root,COG2856@2|Bacteria,1TQAC@1239|Firmicutes,24AMH@186801|Clostridia,27R4F@186928|unclassified Lachnospiraceae	186801|Clostridia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
WZS3_k127_6361500_2	1321782.HMPREF1986_01841	3.051e-44	167.0	COG1487@1|root,COG1487@2|Bacteria,1V9JF@1239|Firmicutes,24NWC@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
WZS3_k127_6361500_3	994573.T472_0214490	5.793e-22	100.0	2DNPM@1|root,32YFZ@2|Bacteria,1VH6K@1239|Firmicutes,25D4P@186801|Clostridia,36M6W@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4829
WZS3_k127_6361500_1	290402.Cbei_3495	3.441e-69	242.0	COG0491@1|root,COG0491@2|Bacteria,1V0KE@1239|Firmicutes,24D1B@186801|Clostridia,36F5X@31979|Clostridiaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
WZS3_k127_6384059_5	195103.CPF_0440	1.807e-46	172.0	COG1840@1|root,COG1840@2|Bacteria,1TSKP@1239|Firmicutes,24C6N@186801|Clostridia,36FXG@31979|Clostridiaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	futA1	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
WZS3_k127_6384059_1	195103.CPF_0441	5.789e-107	365.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,24A64@186801|Clostridia,36F7C@31979|Clostridiaceae	186801|Clostridia	P	ABC-type Fe3 transport system, permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
WZS3_k127_6384059_4	1078085.HMPREF1210_00191	4.553e-60	215.0	COG3842@1|root,COG3842@2|Bacteria,1TS7K@1239|Firmicutes,4HA0K@91061|Bacilli,26EJV@186818|Planococcaceae	91061|Bacilli	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran
WZS3_k127_6384059_0	575594.ACOH01000004_gene1257	4.65e-122	404.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,4HCSJ@91061|Bacilli,3F51K@33958|Lactobacillaceae	91061|Bacilli	S	cog cog1373	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
WZS3_k127_6384059_2	865861.AZSU01000005_gene845	2.568e-99	332.0	COG2103@1|root,COG2103@2|Bacteria,1TPSF@1239|Firmicutes,247KZ@186801|Clostridia,36FJV@31979|Clostridiaceae	186801|Clostridia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
WZS3_k127_6384059_6	1536774.H70357_12145	2.06e-33	134.0	COG3279@1|root,COG3279@2|Bacteria,1VA36@1239|Firmicutes,4HNQ6@91061|Bacilli,26XMD@186822|Paenibacillaceae	91061|Bacilli	KT	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
WZS3_k127_6384059_7	1410665.JNKR01000006_gene801	2.954e-32	128.0	COG1447@1|root,COG1447@2|Bacteria,1VEPM@1239|Firmicutes,4H59T@909932|Negativicutes	909932|Negativicutes	G	PTS system, Lactose/Cellobiose specific IIA subunit	-	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIA
WZS3_k127_6384059_3	469596.HMPREF9488_03020	1.02e-70	250.0	COG3589@1|root,COG3589@2|Bacteria,1TRIY@1239|Firmicutes,3VPJB@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Bacterial protein of unknown function (DUF871)	-	-	-	-	-	-	-	-	-	-	-	-	DUF871
WZS3_k127_6387613_5	642492.Clole_4203	4.948e-45	168.0	COG1309@1|root,COG1309@2|Bacteria,1V1ZJ@1239|Firmicutes,24FQ3@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, tetr family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_6387613_12	1415774.U728_1589	2.333e-11	70.0	COG1595@1|root,COG1595@2|Bacteria,1URHG@1239|Firmicutes,24M2C@186801|Clostridia,36KCA@31979|Clostridiaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
WZS3_k127_6387613_15	203119.Cthe_1273	1.295e-06	60.0	COG2755@1|root,COG2755@2|Bacteria,1UYMR@1239|Firmicutes,24EU1@186801|Clostridia,3WI5J@541000|Ruminococcaceae	186801|Clostridia	E	Alpha-L-arabinofuranosidase B (ABFB) domain	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,RsgI_N
WZS3_k127_6387613_4	1266845.Q783_10625	6.062e-56	203.0	COG2085@1|root,COG2085@2|Bacteria,1V35D@1239|Firmicutes,4HFSW@91061|Bacilli	91061|Bacilli	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
WZS3_k127_6387613_8	547144.HydHO_1090	1.089e-34	136.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
WZS3_k127_6387613_2	1321778.HMPREF1982_02894	6.791e-87	303.0	COG1409@1|root,COG1409@2|Bacteria,1UQCQ@1239|Firmicutes,248P1@186801|Clostridia	186801|Clostridia	M	Ser Thr phosphatase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
WZS3_k127_6387613_11	272558.10173459	9.427e-32	129.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli,1ZC48@1386|Bacillus	91061|Bacilli	G	phosphotransferase system	ptsG	-	2.7.1.199	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00282,M00809	R02631,R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.6,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
WZS3_k127_6387613_7	1211844.CBLM010000088_gene2881	8.003e-37	142.0	COG0607@1|root,COG0607@2|Bacteria,1TU1Y@1239|Firmicutes,3VRN1@526524|Erysipelotrichia	526524|Erysipelotrichia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
WZS3_k127_6387613_13	1031288.AXAA01000002_gene1431	9.258e-11	70.0	COG1943@1|root,COG1943@2|Bacteria,1V553@1239|Firmicutes,2495R@186801|Clostridia,36F6G@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
WZS3_k127_6387613_0	1410668.JNKC01000001_gene1913	1.451e-113	374.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,36V6P@31979|Clostridiaceae	186801|Clostridia	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384,ko:K03387	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WZS3_k127_6387613_3	994573.T472_0203985	6.391e-81	276.0	COG3634@1|root,COG3634@2|Bacteria,1V40Z@1239|Firmicutes,24JKA@186801|Clostridia,36I22@31979|Clostridiaceae	186801|Clostridia	O	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WZS3_k127_6387613_9	402881.Plav_0020	2.857e-34	133.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,1JQAU@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
WZS3_k127_6387613_10	742722.HMPREF9463_01271	4.406e-33	132.0	COG3093@1|root,COG3093@2|Bacteria,2IR2S@201174|Actinobacteria,4CWBD@84998|Coriobacteriia	84998|Coriobacteriia	K	addiction module antidote protein, HigA	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
WZS3_k127_6387613_1	1469948.JPNB01000002_gene3337	3.343e-95	320.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,36F2U@31979|Clostridiaceae	186801|Clostridia	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_6387613_6	1384066.JAGT01000001_gene2166	3.545e-42	167.0	COG0657@1|root,COG0657@2|Bacteria,1V2AW@1239|Firmicutes,24FQJ@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
WZS3_k127_6387613_16	1403313.AXBR01000014_gene2201	6.251e-06	51.0	2BTFW@1|root,32NN5@2|Bacteria,1UB53@1239|Firmicutes,4IMHN@91061|Bacilli,1ZK6C@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6387613_14	931626.Awo_c00900	8.418e-10	59.0	COG2211@1|root,COG2211@2|Bacteria,1UJS2@1239|Firmicutes,25F8F@186801|Clostridia,25X2H@186806|Eubacteriaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS3_k127_6393730_3	469617.FUAG_00326	1.799e-17	86.0	COG1906@1|root,COG1906@2|Bacteria,37972@32066|Fusobacteria	32066|Fusobacteria	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
WZS3_k127_6393730_1	1541959.KQ51_00641	1.553e-45	169.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
WZS3_k127_6393730_2	697281.Mahau_2793	1.3e-38	149.0	COG1146@1|root,COG1146@2|Bacteria,1UIFT@1239|Firmicutes,25EM9@186801|Clostridia	186801|Clostridia	C	Domain of unknown function (DUF2703)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2703
WZS3_k127_6393730_0	994573.T472_0215535	1.105e-155	495.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,24958@186801|Clostridia,36FGQ@31979|Clostridiaceae	186801|Clostridia	P	TIGRFAM Arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
WZS3_k127_6419219_0	1122143.AUEG01000002_gene842	1.677e-68	236.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HAG6@91061|Bacilli,27FRZ@186828|Carnobacteriaceae	91061|Bacilli	S	Aldo/keto reductase family	morA	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_6419219_1	1265503.KB905169_gene190	1.202e-42	174.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WZS3_k127_6442801_4	994573.T472_0207665	9.836e-10	59.0	COG1233@1|root,COG1233@2|Bacteria,1UU71@1239|Firmicutes	1239|Firmicutes	Q	Phytoene dehydrogenase	-	-	5.2.1.13	ko:K09835	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R07512	RC01960	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,NAD_binding_8
WZS3_k127_6442801_2	994573.T472_0207660	1.699e-64	223.0	COG4308@1|root,COG4308@2|Bacteria	2|Bacteria	Q	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	DUF2358,LEH,SnoaL_2
WZS3_k127_6442801_0	994573.T472_0207655	1.162e-106	353.0	COG1028@1|root,COG1028@2|Bacteria,1TRQB@1239|Firmicutes,24NWD@186801|Clostridia,36H3G@31979|Clostridiaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
WZS3_k127_6442801_1	1122143.AUEG01000002_gene798	3.024e-66	237.0	arCOG12964@1|root,2Z7HP@2|Bacteria,1UZIT@1239|Firmicutes,4HG52@91061|Bacilli,27G60@186828|Carnobacteriaceae	91061|Bacilli	S	Tocopherol cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Tocopherol_cycl
WZS3_k127_6442801_3	293826.Amet_3349	4.279e-25	113.0	COG1266@1|root,COG1266@2|Bacteria,1V47I@1239|Firmicutes,24H0K@186801|Clostridia,36IHA@31979|Clostridiaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
WZS3_k127_6454140_0	1235835.C814_01710	0.0	1058.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
WZS3_k127_6454140_1	742733.HMPREF9469_02318	4.172e-45	168.0	COG1397@1|root,COG1397@2|Bacteria,1U2AQ@1239|Firmicutes,24KT9@186801|Clostridia,223XP@1506553|Lachnoclostridium	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
WZS3_k127_6454722_2	1123308.KB904539_gene554	2.276e-21	97.0	COG2893@1|root,COG2893@2|Bacteria,1VES9@1239|Firmicutes,4HPE3@91061|Bacilli	91061|Bacilli	G	IIa component	agaF	-	2.7.1.191	ko:K02744,ko:K02793	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	M00276,M00277,M00287	R02630,R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
WZS3_k127_6454722_1	1280692.AUJL01000022_gene535	1.87e-111	372.0	COG2222@1|root,COG2222@2|Bacteria,1TQUT@1239|Firmicutes,24BTJ@186801|Clostridia,36FX3@31979|Clostridiaceae	186801|Clostridia	M	isomerase	agaS	-	2.6.1.16	ko:K00820,ko:K02082	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
WZS3_k127_6454722_0	1232449.BAHV02000021_gene1083	1.524e-118	387.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
WZS3_k127_6465107_7	650150.ERH_1051	6.056e-73	249.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,3VPMP@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
WZS3_k127_6465107_2	491915.Aflv_2133	1.205e-102	354.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,21W6G@150247|Anoxybacillus	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
WZS3_k127_6465107_4	702450.CUW_2468	1.903e-93	317.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,3VPZ3@526524|Erysipelotrichia	1239|Firmicutes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
WZS3_k127_6465107_6	1121929.KB898672_gene4039	5.103e-86	298.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HXXQ@91061|Bacilli,47180@74385|Gracilibacillus	91061|Bacilli	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
WZS3_k127_6465107_0	1391646.AVSU01000057_gene1185	2.275e-146	471.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,25SXE@186804|Peptostreptococcaceae	186801|Clostridia	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS3_k127_6465107_1	1301100.HG529378_gene4074	1.077e-135	437.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,36EGD@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS3_k127_6465107_3	545696.HOLDEFILI_03663	3.457e-94	320.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,3VQ79@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_AC39
WZS3_k127_6465107_5	1121874.KB892377_gene1444	1.958e-90	311.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,3VNY1@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Belongs to the V-ATPase 116 kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
WZS3_k127_6506794_2	545696.HOLDEFILI_01582	1.531e-14	74.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,3VNPC@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Belongs to the NqrB RnfD family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,NQR2_RnfD_RnfE
WZS3_k127_6506794_0	545696.HOLDEFILI_01581	4.6e-171	546.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,3VNWW@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_10,Fer4_17,Fer4_4,Fer4_7,RnfC_N,SLBB
WZS3_k127_6506794_1	1211819.CALK01000013_gene242	6.898e-65	233.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,3VPBT@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	ApbE
WZS3_k127_6532917_1	758.BBIX01000008_gene1370	2.232e-128	420.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1Y9RP@135625|Pasteurellales	135625|Pasteurellales	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
WZS3_k127_6532917_0	1410668.JNKC01000001_gene1209	5.784e-152	490.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,36E70@31979|Clostridiaceae	186801|Clostridia	C	flavodoxin nitric oxide synthase	norV	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B
WZS3_k127_6532917_5	411489.CLOL250_01407	2.829e-52	193.0	COG3442@1|root,COG3442@2|Bacteria	2|Bacteria	S	CobB/CobQ-like glutamine amidotransferase domain	cobQ	-	-	ko:K07009	-	-	-	-	ko00000	-	-	iSB619.SA_RS09800	GATase_3
WZS3_k127_6532917_2	1410622.JNKY01000012_gene2222	3.61e-105	357.0	COG0770@1|root,COG3442@1|root,COG0770@2|Bacteria,COG3442@2|Bacteria,1TRG9@1239|Firmicutes,248MX@186801|Clostridia	186801|Clostridia	M	Mur ligase middle domain protein	murE1	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF1727,Mur_ligase_M
WZS3_k127_6532917_6	445972.ANACOL_01312	1.32e-06	56.0	COG4818@1|root,COG4818@2|Bacteria,1UQ1I@1239|Firmicutes,24SH6@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
WZS3_k127_6532917_4	1321778.HMPREF1982_01914	6.784e-72	249.0	COG1011@1|root,COG1011@2|Bacteria,1UIE8@1239|Firmicutes,24I5V@186801|Clostridia,26B6X@186813|unclassified Clostridiales	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
WZS3_k127_6532917_3	871968.DESME_00600	1.107e-77	262.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,260Q6@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
WZS3_k127_6574432_4	642492.Clole_4203	9.049e-19	89.0	COG1309@1|root,COG1309@2|Bacteria,1V1ZJ@1239|Firmicutes,24FQ3@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, tetr family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
WZS3_k127_6574432_2	1235790.C805_01444	8.563e-53	196.0	COG0655@1|root,COG0655@2|Bacteria,1UI36@1239|Firmicutes,247R8@186801|Clostridia,25W5U@186806|Eubacteriaceae	186801|Clostridia	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
WZS3_k127_6574432_1	309798.COPRO5265_1469	4.803e-68	242.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,42G9R@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
WZS3_k127_6574432_0	1487921.DP68_05545	2.603e-157	508.0	COG1397@1|root,COG1397@2|Bacteria,1TSKF@1239|Firmicutes,25DA4@186801|Clostridia,36VE3@31979|Clostridiaceae	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
WZS3_k127_6574432_3	1487921.DP68_05540	1.528e-45	170.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,36FIQ@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
WZS3_k127_6583500_0	1280673.AUJJ01000012_gene1910	2.397e-118	394.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,4BXQU@830|Butyrivibrio	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
WZS3_k127_6589642_3	445971.ANASTE_00865	2.503e-18	85.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,25VUT@186806|Eubacteriaceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	expZ	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
WZS3_k127_6589642_2	1121344.JHZO01000003_gene837	4.393e-21	96.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,3WHIN@541000|Ruminococcaceae	186801|Clostridia	S	ATPases associated with a variety of cellular activities	expZ	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
WZS3_k127_6589642_0	350688.Clos_2225	1.737e-50	184.0	2DN4N@1|root,32UIA@2|Bacteria,1VA2T@1239|Firmicutes,24JJM@186801|Clostridia,36KM0@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF2812)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
WZS3_k127_6589642_1	1321784.HMPREF1987_01798	2.047e-34	136.0	COG1695@1|root,COG1695@2|Bacteria,1V9XX@1239|Firmicutes,24RE5@186801|Clostridia,25TXF@186804|Peptostreptococcaceae	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
WZS3_k127_6589642_4	1347087.CBYO010000022_gene3437	4.696e-18	85.0	2CHCP@1|root,32S5R@2|Bacteria,1V3HI@1239|Firmicutes,4HGYA@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
WZS3_k127_6612867_4	1120973.AQXL01000131_gene2108	3.291e-25	106.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF_1	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
WZS3_k127_6612867_2	521460.Athe_2047	2.421e-48	176.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,42GKU@68295|Thermoanaerobacterales	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
WZS3_k127_6612867_3	1123313.ATUT01000004_gene172	5.579e-40	156.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,3VP45@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
WZS3_k127_6612867_5	1008457.BAEX01000019_gene1778	5.678e-07	57.0	COG2091@1|root,COG2091@2|Bacteria,4NSBI@976|Bacteroidetes,1HYHB@117743|Flavobacteriia,47IDA@76831|Myroides	976|Bacteroidetes	H	4'-phosphopantetheinyl transferase superfamily	sfp	-	-	-	-	-	-	-	-	-	-	-	ACPS
WZS3_k127_6612867_0	1321778.HMPREF1982_03035	5.532e-114	373.0	COG1586@1|root,COG1586@2|Bacteria,1TQ7S@1239|Firmicutes,2480M@186801|Clostridia,26A82@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	-	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
WZS3_k127_6612867_1	318464.IO99_15935	5.388e-72	245.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,36FAN@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
WZS3_k127_6624606_3	994573.T472_0213820	2.447e-56	199.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,36F8C@31979|Clostridiaceae	186801|Clostridia	C	Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_10,RnfC_N,SLBB
WZS3_k127_6624606_0	1410668.JNKC01000008_gene2692	9.53e-134	442.0	COG4658@1|root,COG4659@1|root,COG4658@2|Bacteria,COG4659@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,36FI0@31979|Clostridiaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,NQR2_RnfD_RnfE
WZS3_k127_6624606_4	1211819.CALK01000013_gene239	6.683e-41	156.0	COG4659@1|root,COG4659@2|Bacteria,1V784@1239|Firmicutes,3VQUG@526524|Erysipelotrichia	526524|Erysipelotrichia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
WZS3_k127_6624606_1	1211819.CALK01000013_gene238	4.196e-80	272.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,3VPRR@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	-	-	-	-	-	-	-	-	-	Rnf-Nqr
WZS3_k127_6624606_2	1232449.BAHV02000016_gene1857	9.645e-58	203.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,268RC@186813|unclassified Clostridiales	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
WZS3_k127_6640449_0	665956.HMPREF1032_01474	6.739e-153	496.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_6640449_1	545696.HOLDEFILI_00835	3.038e-56	210.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,3VPAD@526524|Erysipelotrichia	526524|Erysipelotrichia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
WZS3_k127_6645087_2	646529.Desaci_2495	5.235e-20	92.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,260HU@186807|Peptococcaceae	186801|Clostridia	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	HD
WZS3_k127_6645087_0	1121289.JHVL01000033_gene2665	1.771e-194	619.0	COG2978@1|root,COG2978@2|Bacteria,1TPDU@1239|Firmicutes,24BJ1@186801|Clostridia	186801|Clostridia	H	Transporter	-	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
WZS3_k127_6645087_1	1121289.JHVL01000033_gene2664	3.35e-157	505.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,36DRG@31979|Clostridiaceae	186801|Clostridia	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_6654082_3	1123405.AUMM01000015_gene2367	1.576e-33	130.0	2B9Z2@1|root,323CP@2|Bacteria,1VE7M@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ToxN_toxin
WZS3_k127_6654082_0	1211819.CALK01000009_gene2735	3.869e-83	278.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,3VPII@526524|Erysipelotrichia	526524|Erysipelotrichia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
WZS3_k127_6654082_5	545696.HOLDEFILI_01919	1.358e-22	98.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,3VRK2@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
WZS3_k127_6654082_2	1211844.CBLM010000105_gene1055	8.513e-53	188.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,3VQU8@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
WZS3_k127_6654082_4	1232452.BAIB02000013_gene2218	5.802e-24	114.0	COG3012@1|root,COG3012@2|Bacteria,1UK0V@1239|Firmicutes,24DYG@186801|Clostridia	186801|Clostridia	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
WZS3_k127_6654082_1	552396.HMPREF0863_01809	3.719e-67	237.0	COG0510@1|root,COG0510@2|Bacteria,1V8JR@1239|Firmicutes,3VQUR@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
WZS3_k127_6665401_0	1410658.JHWI01000024_gene1505	4.781e-92	317.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,3VPF4@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
WZS3_k127_6665401_1	1410674.JNKU01000034_gene1147	1.293e-53	198.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,4HADZ@91061|Bacilli,3F48R@33958|Lactobacillaceae	91061|Bacilli	G	Catalyzes the interconversion of alpha and beta anomers of maltose	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
WZS3_k127_66664_1	658659.HMPREF0983_01147	3.024e-47	181.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,3VPAJ@526524|Erysipelotrichia	526524|Erysipelotrichia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
WZS3_k127_66664_0	545696.HOLDEFILI_03093	1.205e-236	741.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,3VP1H@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
WZS3_k127_6673560_5	1280689.AUJC01000001_gene2615	8.363e-55	203.0	COG2971@1|root,COG2971@2|Bacteria,1V47Z@1239|Firmicutes,25CM0@186801|Clostridia,36WXW@31979|Clostridiaceae	186801|Clostridia	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
WZS3_k127_6673560_2	1122143.AUEG01000009_gene94	6.855e-81	279.0	COG0673@1|root,COG0673@2|Bacteria,1UZRV@1239|Firmicutes,4HEWB@91061|Bacilli,27H5K@186828|Carnobacteriaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	ysjB	-	-	ko:K03810	-	-	-	-	ko00000	-	-	-	GFO_IDH_MocA
WZS3_k127_6673560_1	1216932.CM240_0431	6.199e-89	301.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,36EFN@31979|Clostridiaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
WZS3_k127_6673560_4	293826.Amet_3690	1.285e-60	221.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia,36DNH@31979|Clostridiaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
WZS3_k127_6673560_6	1232447.BAHW02000039_gene2676	3.388e-32	128.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia	186801|Clostridia	S	MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
WZS3_k127_6673560_7	224308.BSU11890	1.357e-17	89.0	COG1670@1|root,COG1670@2|Bacteria,1V49W@1239|Firmicutes,4HHAP@91061|Bacilli,1ZGG6@1386|Bacillus	91061|Bacilli	J	Alanine acetyltransferase	yjcK	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
WZS3_k127_6673560_0	1121874.KB892377_gene828	1.181e-164	534.0	COG0517@1|root,COG1227@1|root,COG4109@1|root,COG0517@2|Bacteria,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,3VPA0@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Psort location Cytoplasmic, score	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
WZS3_k127_6673560_3	1195236.CTER_3095	2.146e-62	222.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,249QZ@186801|Clostridia,3WNFX@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase NAD-binding domain protein	-	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
WZS3_k127_6676968_9	471223.GWCH70_1268	4.651e-31	125.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,1WFRE@129337|Geobacillus	91061|Bacilli	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
WZS3_k127_6676968_4	658659.HMPREF0983_03715	2.478e-38	147.0	2DSKI@1|root,33GI1@2|Bacteria,1UMN7@1239|Firmicutes,3VUXN@526524|Erysipelotrichia	526524|Erysipelotrichia	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
WZS3_k127_6676968_5	1232449.BAHV02000014_gene1988	3.345e-38	148.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia	186801|Clostridia	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
WZS3_k127_6676968_1	1211819.CALK01000008_gene2693	7.075e-205	653.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,3VNV1@526524|Erysipelotrichia	526524|Erysipelotrichia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_6676968_0	1211819.CALK01000008_gene2692	1.119e-230	729.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,3VPVI@526524|Erysipelotrichia	526524|Erysipelotrichia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
WZS3_k127_6676968_3	268407.PWYN_19155	2.377e-40	151.0	COG2849@1|root,COG2849@2|Bacteria,1VBMK@1239|Firmicutes,4HKZ4@91061|Bacilli,272XN@186822|Paenibacillaceae	91061|Bacilli	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_6676968_8	350688.Clos_0243	2.67e-31	128.0	COG4508@1|root,COG4508@2|Bacteria,1V6PI@1239|Firmicutes,24G28@186801|Clostridia,36IGY@31979|Clostridiaceae	186801|Clostridia	S	PFAM dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
WZS3_k127_6676968_2	650150.ERH_0428	1.782e-146	472.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,3VPWP@526524|Erysipelotrichia	526524|Erysipelotrichia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
WZS3_k127_6676968_7	908340.HMPREF9406_1411	1.486e-36	144.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,36K1I@31979|Clostridiaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
WZS3_k127_6676968_6	1211819.CALK01000008_gene2683	4.853e-38	146.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,3VPI7@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
WZS3_k127_672764_1	1123009.AUID01000014_gene1789	1.85e-87	297.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,26AI3@186813|unclassified Clostridiales	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
WZS3_k127_672764_0	1499683.CCFF01000017_gene1774	1.624e-122	401.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
WZS3_k127_6739011_2	657322.FPR_25530	1.595e-54	199.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3WHQA@541000|Ruminococcaceae	186801|Clostridia	H	Carbohydrate kinase, FGGY family protein	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
WZS3_k127_6739011_0	1226325.HMPREF1548_03669	1.464e-179	570.0	COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,2487G@186801|Clostridia,36HH0@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
WZS3_k127_6739011_1	411467.BACCAP_00214	9.647e-116	378.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,26A0D@186813|unclassified Clostridiales	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
WZS3_k127_6743443_0	565655.ECBG_01315	1.587e-17	86.0	COG2365@1|root,COG2365@2|Bacteria,1VA24@1239|Firmicutes,4HMSH@91061|Bacilli,4B3VE@81852|Enterococcaceae	91061|Bacilli	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
WZS3_k127_674534_1	1121874.KB892377_gene1357	1.247e-26	113.0	COG4537@1|root,COG4537@2|Bacteria,1UKCM@1239|Firmicutes,3VQS5@526524|Erysipelotrichia	526524|Erysipelotrichia	U	Prokaryotic N-terminal methylation motif	comGC	-	-	ko:K02245	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	N_methyl
WZS3_k127_674534_2	706433.HMPREF9430_00638	8.684e-11	67.0	2DS86@1|root,33EYN@2|Bacteria,1VMU6@1239|Firmicutes,3VS52@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Prepilin-type cleavage methylation N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
WZS3_k127_674534_0	1232449.BAHV02000012_gene2296	4.957e-85	285.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,268CB@186813|unclassified Clostridiales	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
WZS3_k127_6745363_0	293826.Amet_3758	3.585e-57	203.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,36DCJ@31979|Clostridiaceae	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
WZS3_k127_6745363_1	1121924.ATWH01000009_gene18	5.857e-07	58.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4FMNS@85023|Microbacteriaceae	201174|Actinobacteria	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
WZS3_k127_6760092_0	1203606.HMPREF1526_03144	2.721e-150	482.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36F8M@31979|Clostridiaceae	186801|Clostridia	C	formate acetyltransferase	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
WZS3_k127_6761143_0	545696.HOLDEFILI_02073	2.285e-146	472.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,3VNZ1@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b,tRNA_edit
WZS3_k127_6762604_1	315730.BcerKBAB4_2814	6.895e-16	81.0	COG1695@1|root,COG1695@2|Bacteria,1VA1N@1239|Firmicutes,4HMNQ@91061|Bacilli,1ZI3V@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator PadR-like family	XK27_08645	-	-	-	-	-	-	-	-	-	-	-	PadR
WZS3_k127_6762604_0	994573.T472_0219380	1.476e-86	291.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
WZS3_k127_6798340_0	665956.HMPREF1032_03033	2.456e-137	443.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia,3WIIP@541000|Ruminococcaceae	186801|Clostridia	V	LD-carboxypeptidase	mccF	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
WZS3_k127_6798340_1	509191.AEDB02000065_gene605	2.834e-56	199.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia,3WI86@541000|Ruminococcaceae	186801|Clostridia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
WZS3_k127_680014_4	650150.ERH_0567	4.959e-21	102.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,3VQ6M@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Cell cycle protein, FtsW RodA SpoVE family	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
WZS3_k127_680014_1	633697.EubceDRAFT1_0764	7.112e-124	418.0	COG0531@1|root,COG0531@2|Bacteria,1UIRN@1239|Firmicutes,25EQE@186801|Clostridia,25WN2@186806|Eubacteriaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
WZS3_k127_680014_2	620914.JH621250_gene2211	3.401e-65	235.0	COG0110@1|root,COG0110@2|Bacteria,4NR4W@976|Bacteroidetes,1IK8T@117743|Flavobacteriia	976|Bacteroidetes	S	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
WZS3_k127_680014_3	658659.HMPREF0983_01271	8.556e-60	213.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,3VPVU@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
WZS3_k127_680014_0	545696.HOLDEFILI_01848	5.933e-202	635.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,3VNVQ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
WZS3_k127_6836070_3	545696.HOLDEFILI_00188	1.313e-09	60.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,3VP9C@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
WZS3_k127_6836070_1	1121874.KB892380_gene1548	1.017e-140	459.0	COG0546@1|root,COG0682@1|root,COG0546@2|Bacteria,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,3VPIK@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	HAD_2,LGT
WZS3_k127_6836070_2	1211819.CALK01000033_gene1396	7.994e-124	404.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,3VP2D@526524|Erysipelotrichia	526524|Erysipelotrichia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
WZS3_k127_6836070_0	1211819.CALK01000033_gene1397	0.0	1308.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,3VNRB@526524|Erysipelotrichia	526524|Erysipelotrichia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
WZS3_k127_704273_0	871963.Desdi_0579	3.544e-42	169.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,266TW@186807|Peptococcaceae	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
WZS3_k127_741346_4	592026.GCWU0000282_002557	4.479e-13	70.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WZS3_k127_741346_2	457412.RSAG_03432	3.271e-19	89.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,24QMD@186801|Clostridia,3WM6E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_741346_1	1449342.JQMR01000001_gene1161	2.735e-24	112.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,27HKF@186828|Carnobacteriaceae	91061|Bacilli	S	SOS response associated peptidase (SRAP)	yoqW	-	-	-	-	-	-	-	-	-	-	-	SRAP
WZS3_k127_741346_0	1139996.OMQ_00302	6.811e-101	336.0	COG0656@1|root,COG0656@2|Bacteria,1TPWT@1239|Firmicutes,4HCQY@91061|Bacilli,4B11D@81852|Enterococcaceae	91061|Bacilli	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
WZS3_k127_741346_3	545696.HOLDEFILI_03011	1.206e-13	78.0	2EPI0@1|root,33H4N@2|Bacteria,1VNNS@1239|Firmicutes,3VS8T@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_753700_0	1321778.HMPREF1982_04395	6.533e-112	365.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,268B5@186813|unclassified Clostridiales	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
WZS3_k127_753700_1	1321778.HMPREF1982_04396	2.534e-63	220.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,267J7@186813|unclassified Clostridiales	186801|Clostridia	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
WZS3_k127_753774_0	158190.SpiGrapes_1805	1.095e-37	158.0	COG3275@1|root,COG3437@1|root,COG3275@2|Bacteria,COG3437@2|Bacteria,2JBG1@203691|Spirochaetes	203691|Spirochaetes	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GGDEF,HD
WZS3_k127_753774_1	431943.CKL_2492	1.071e-16	81.0	COG1309@1|root,COG1309@2|Bacteria,1U9UE@1239|Firmicutes,24F64@186801|Clostridia,36W0I@31979|Clostridiaceae	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
WZS3_k127_754266_1	326297.Sama_3115	5.703e-18	98.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q9VG@267890|Shewanellaceae	1236|Gammaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
WZS3_k127_754266_0	1004149.AFOE01000004_gene2434	1.712e-40	169.0	COG4251@1|root,COG4251@2|Bacteria,4NK4U@976|Bacteroidetes,1I0AQ@117743|Flavobacteriia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9
WZS3_k127_776563_1	1226325.HMPREF1548_04118	2.756e-44	168.0	COG1091@1|root,COG1091@2|Bacteria,1TSX1@1239|Firmicutes,249SC@186801|Clostridia,36R9R@31979|Clostridiaceae	186801|Clostridia	M	dTDP-4-dehydrorhamnose reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RmlD_sub_bind
WZS3_k127_776563_2	37659.JNLN01000001_gene341	1.717e-35	141.0	COG1309@1|root,COG1309@2|Bacteria,1VN91@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K19736	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
WZS3_k127_776563_0	37659.JNLN01000001_gene340	1.734e-78	272.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,36DHN@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
WZS3_k127_793536_0	398512.JQKC01000006_gene746	1.224e-133	435.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WGV5@541000|Ruminococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
WZS3_k127_793536_1	1211819.CALK01000005_gene2436	3.374e-52	191.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,3VRPV@526524|Erysipelotrichia	526524|Erysipelotrichia	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
WZS3_k127_793536_2	397290.C810_04185	1.871e-14	77.0	COG2856@1|root,COG2856@2|Bacteria,1TQAC@1239|Firmicutes,24AMH@186801|Clostridia,27R4F@186928|unclassified Lachnospiraceae	186801|Clostridia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
WZS3_k127_7985_3	1449336.JQLO01000001_gene507	1.756e-59	210.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,4H9NC@91061|Bacilli,27G1Z@186828|Carnobacteriaceae	91061|Bacilli	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
WZS3_k127_7985_6	908340.HMPREF9406_3602	1.766e-19	91.0	COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,24939@186801|Clostridia,36GQ5@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
WZS3_k127_7985_1	546270.GEMHA0001_0751	7.181e-101	340.0	COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,4HA73@91061|Bacilli,3WDXI@539002|Bacillales incertae sedis	91061|Bacilli	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
WZS3_k127_7985_4	1121874.KB892380_gene1785	6.917e-39	156.0	COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes	1239|Firmicutes	T	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
WZS3_k127_7985_2	1232449.BAHV02000010_gene2892	3.229e-71	252.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,267QV@186813|unclassified Clostridiales	186801|Clostridia	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
WZS3_k127_7985_0	1408423.JHYA01000005_gene1871	5.211e-210	670.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4H2IK@909932|Negativicutes	909932|Negativicutes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
WZS3_k127_7985_5	1211819.CALK01000042_gene3164	3.087e-36	138.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,3VNXH@526524|Erysipelotrichia	526524|Erysipelotrichia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
WZS3_k127_807341_4	326423.RBAM_030690	6.405e-11	64.0	COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,4IRA4@91061|Bacilli,1ZRSW@1386|Bacillus	91061|Bacilli	P	Heavy-metal-associated domain	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
WZS3_k127_807341_1	357809.Cphy_2119	6.306e-137	449.0	COG2608@1|root,COG2836@1|root,COG4633@1|root,COG2608@2|Bacteria,COG2836@2|Bacteria,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,249HC@186801|Clostridia,21ZAN@1506553|Lachnoclostridium	186801|Clostridia	P	cytochrome c biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
WZS3_k127_807341_7	373903.Hore_13320	0.0001125	48.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WASA@53433|Halanaerobiales	186801|Clostridia	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
WZS3_k127_807341_0	1469948.JPNB01000001_gene1226	0.0	1049.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,36DJE@31979|Clostridiaceae	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
WZS3_k127_807341_6	158190.SpiGrapes_0733	6.753e-07	60.0	COG3462@1|root,COG3462@2|Bacteria,2JAMV@203691|Spirochaetes	203691|Spirochaetes	S	membrane protein (DUF2078)	-	-	-	-	-	-	-	-	-	-	-	-	-
WZS3_k127_807341_5	504728.K649_01100	2.573e-08	58.0	COG3462@1|root,COG3462@2|Bacteria,1WKI9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
WZS3_k127_807341_3	1410668.JNKC01000001_gene1793	8.794e-41	154.0	COG3339@1|root,COG3339@2|Bacteria,1VB9N@1239|Firmicutes,24NG4@186801|Clostridia,36M3B@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
WZS3_k127_807341_2	1121334.KB911066_gene1002	6.152e-107	353.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3WGR3@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
WZS3_k127_84358_1	1536769.P40081_27555	8.784e-26	116.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,4HHKY@91061|Bacilli,26S6P@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
WZS3_k127_84358_0	1449050.JNLE01000003_gene2007	6.995e-168	535.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,36E3W@31979|Clostridiaceae	186801|Clostridia	G	transporter	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
WZS3_k127_863119_2	509191.AEDB02000018_gene247	1.423e-14	75.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3WGK3@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
WZS3_k127_863119_0	931626.Awo_c00900	1.428e-146	473.0	COG2211@1|root,COG2211@2|Bacteria,1UJS2@1239|Firmicutes,25F8F@186801|Clostridia,25X2H@186806|Eubacteriaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
WZS3_k127_863119_1	1511.CLOST_0398	1.192e-21	95.0	COG5012@1|root,COG5012@2|Bacteria,1V5DK@1239|Firmicutes,25AZT@186801|Clostridia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
WZS3_k127_872596_0	552396.HMPREF0863_00309	2.558e-101	340.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,3VNVX@526524|Erysipelotrichia	526524|Erysipelotrichia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
WZS3_k127_890561_2	580331.Thit_0777	1.26e-24	106.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,42FSY@68295|Thermoanaerobacterales	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02100	DHDPS
WZS3_k127_890561_1	1540257.JQMW01000011_gene1411	3.1e-39	155.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,36DQC@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
WZS3_k127_890561_0	1449342.JQMR01000001_gene321	5.78e-89	299.0	COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli,27G3F@186828|Carnobacteriaceae	91061|Bacilli	E	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate	dapH	-	2.3.1.117,2.3.1.89	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	M00016,M00525	R04364,R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU14180	DapH_N,Hexapep
WZS3_k127_89621_2	999413.HMPREF1094_00986	1.023e-124	406.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,3VNYA@526524|Erysipelotrichia	526524|Erysipelotrichia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
WZS3_k127_89621_4	1069080.KB913028_gene259	4.979e-53	207.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,1V9Y7@1239|Firmicutes,4H568@909932|Negativicutes	909932|Negativicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
WZS3_k127_89621_0	1286171.EAL2_c21780	1.722e-210	661.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,25VBF@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
WZS3_k127_89621_3	545696.HOLDEFILI_00958	3.5e-54	195.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,3VQIB@526524|Erysipelotrichia	526524|Erysipelotrichia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_10,MafB19-deam
WZS3_k127_89621_1	1211819.CALK01000049_gene1509	4.586e-147	476.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,3VPGE@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
WZS3_k127_910202_0	1158609.I586_03327	1.125e-85	292.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,4B20Q@81852|Enterococcaceae	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
WZS3_k127_910202_1	411902.CLOBOL_07317	2.458e-30	123.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,220FR@1506553|Lachnoclostridium	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
WZS3_k127_910202_2	1128398.Curi_c00760	0.0002187	46.0	COG0403@1|root,COG0403@2|Bacteria,1TQGG@1239|Firmicutes,2492A@186801|Clostridia,268QF@186813|unclassified Clostridiales	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
WZS3_k127_924487_1	1158612.I580_03102	5.774e-26	109.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,4HD97@91061|Bacilli,4B05Y@81852|Enterococcaceae	91061|Bacilli	G	1-deoxy-D-xylulose-5-phosphate synthase	tktN	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
WZS3_k127_924487_0	1123313.ATUT01000017_gene558	2.06e-91	310.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,3VQ55@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
WZS3_k127_924519_1	1121929.KB898662_gene423	5.515e-16	83.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,4HFKJ@91061|Bacilli	91061|Bacilli	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
WZS3_k127_924519_0	1121929.KB898662_gene596	9.74e-162	527.0	COG3119@1|root,COG3119@2|Bacteria,1TQD2@1239|Firmicutes,4HEBR@91061|Bacilli	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
WZS3_k127_945687_2	340099.Teth39_1436	1.271e-10	67.0	COG5416@1|root,COG5416@2|Bacteria,1VK4W@1239|Firmicutes,24RJX@186801|Clostridia,42HFD@68295|Thermoanaerobacterales	186801|Clostridia	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
WZS3_k127_945687_0	1235796.C815_02070	6.083e-116	381.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes	1239|Firmicutes	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS3_k127_945687_1	1347086.CCBA010000027_gene3466	5.66e-28	114.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	oppD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
WZS3_k127_947888_2	428127.EUBDOL_01316	2.267e-39	150.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,3VR0K@526524|Erysipelotrichia	526524|Erysipelotrichia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
WZS3_k127_947888_1	642492.Clole_1394	3.653e-56	203.0	COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,24AZ3@186801|Clostridia	186801|Clostridia	S	Na channel or pump	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
WZS3_k127_947888_3	1211819.CALK01000004_gene2361	2.202e-24	111.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,3VQZK@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	MTS,Methyltransf_31
WZS3_k127_947888_0	545696.HOLDEFILI_03183	4.363e-93	316.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,3VPI1@526524|Erysipelotrichia	526524|Erysipelotrichia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
WZS3_k127_982249_1	658659.HMPREF0983_03150	1.125e-58	209.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,3VP46@526524|Erysipelotrichia	526524|Erysipelotrichia	F	Belongs to the GARS family	purD	-	-	-	-	-	-	-	-	-	-	-	GARS_A,GARS_C,GARS_N
WZS3_k127_982249_0	138119.DSY4678	2.061e-144	464.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,2614E@186807|Peptococcaceae	186801|Clostridia	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
WZS3_k127_982249_3	857293.CAAU_0158	4.697e-24	104.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,36MSQ@31979|Clostridiaceae	186801|Clostridia	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
WZS3_k127_982249_2	1511.CLOST_0767	1.294e-28	119.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
WZS3_k127_982249_4	1230342.CTM_00615	1.548e-22	97.0	COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,36EYM@31979|Clostridiaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Fer4,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
WZS3_k127_985914_0	1211819.CALK01000008_gene2656	2.529e-31	128.0	COG0715@1|root,COG0715@2|Bacteria,1TTDY@1239|Firmicutes,3VQG2@526524|Erysipelotrichia	526524|Erysipelotrichia	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	VitK2_biosynth
WZS3_k127_999833_3	946235.CAER01000008_gene479	1.37e-83	288.0	COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HCIG@91061|Bacilli,23IMW@182709|Oceanobacillus	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WZS3_k127_999833_1	1235796.C815_01748	5.731e-111	368.0	COG0673@1|root,COG0673@2|Bacteria,1TR8S@1239|Firmicutes	1239|Firmicutes	G	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
WZS3_k127_999833_4	1227349.C170_15260	2.549e-35	145.0	COG1737@1|root,COG1737@2|Bacteria,1W736@1239|Firmicutes,4I2TP@91061|Bacilli,26Y1S@186822|Paenibacillaceae	91061|Bacilli	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
WZS3_k127_999833_6	877415.JNJQ01000005_gene1365	3.47e-11	73.0	COG0671@1|root,COG0671@2|Bacteria,1VE9B@1239|Firmicutes,3VRVK@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
WZS3_k127_999833_0	994573.T472_0200465	1.257e-118	391.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,36ICK@31979|Clostridiaceae	186801|Clostridia	P	Chromate	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
WZS3_k127_999833_2	742735.HMPREF9467_01807	3.518e-95	325.0	COG1906@1|root,COG1906@2|Bacteria,1V5AX@1239|Firmicutes,24DIQ@186801|Clostridia,21ZT7@1506553|Lachnoclostridium	1239|Firmicutes	S	Protein of unknown function (DUF401)	-	-	-	ko:K09133	-	-	-	-	ko00000	-	-	-	DUF401
WZS3_k127_999833_5	1121324.CLIT_2c00360	4.008e-32	125.0	COG1917@1|root,COG1917@2|Bacteria,1VDBA@1239|Firmicutes,24NXM@186801|Clostridia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
## 2132 queries scanned
## Total time (seconds): 158.3014645576477
## Rate: 13.47 q/s